CN110289069A - Analysis method, device, computer equipment and the storage medium of clinical data - Google Patents
Analysis method, device, computer equipment and the storage medium of clinical data Download PDFInfo
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Abstract
This application involves a kind of analysis method of clinical data, device, computer equipment and storage mediums, and by obtaining the operational order of clinical data analysis, and operational order includes medicine name, disease type and analysis process；According to medicine name and disease type, corresponding clinical data is obtained from the clinical database prestored；And clinical data analysis model corresponding with analysis process is selected according to analysis process；To carry out drug side-effect analysis to the clinical data got by clinical data analysis model, the result of drug side-effect analysis is obtained.The reasonable utilization to clinical data is realized, solves the technical issues of clinical data is not effectively excavated and utilized in traditional technology.
Description
Technical field
This application involves Analysis of Medical Treatment Data fields, more particularly to a kind of analysis method of clinical data, device, calculating
Machine equipment and storage medium.
Background technique
What traditional mode of drug followed is the mass treatment of drug, has ignored the individual difference of disposition of drug and effect
It is different, it can not accomplish the accurate administration of drug.With the development of pharmaceutical technology, traditional dosage regimen is no longer satisfied people
Expectation to therapeutic effect.In recent years, it in drug treatment, by observing curative effect of medication, monitors in patient's biological fluid
The concentration of drug and active metabolite, and pharmacokinetics and pharmacodynamics basic theories are combined, instruct clinical rational drug use side
The formulation and adjustment of case, to realize optimum therapeuticing effect.
Meanwhile along with the development of medical information process, health examination, public health, disease detection, medical system are produced
Clinical data of magnanimity high value, including electronic health record data, pathological analysis data, Residential soil etc. are given birth to.But
In traditional technology, there is no effectively excavated and utilized these clinical datas.
Summary of the invention
Based on this, it is necessary to effectively not excavated and be utilized for the clinical data of magnanimity high value in traditional technology
The technical issues of, analysis method, device, computer equipment and the storage medium of a kind of clinical data are provided.
A kind of analysis method of clinical data, which comprises
The operational order of clinical data analysis is obtained, the operational order includes medicine name, disease type and analysis stream
Journey；
According to the medicine name and the disease type, corresponding clinical number is obtained from the clinical database prestored
According to；
Clinical data analysis model corresponding with the analysis process is selected according to the analysis process；
By the clinical data analysis model, drug side-effect analysis is carried out to the clinical data got, and obtain
The result of drug side-effect analysis.
The medicine name includes the first medicine name in one of the embodiments, and the analysis process is single medicine
Object side effect analysis process；It is described according to the medicine name and the disease type, obtained from the clinical database prestored
Corresponding clinical data, comprising:
According to first medicine name and the disease type, corresponding first is obtained from the clinical database prestored
Clinical data；
It is described that clinical data analysis model corresponding with the analysis process is selected according to the analysis process, comprising:
It is selected according to the single medicine side effect analysis process corresponding with the single medicine side effect analysis process
Single medicine side effect analysis model；
It is described by the clinical data analysis model, drug side-effect analysis, packet are carried out to the clinical data got
It includes:
By the single medicine side effect analysis model, drug side-effect point is carried out to the first clinical data got
Analysis.
In one of the embodiments, the medicine name include the second medicine name and third medicine name, described point
Analysis process is drug combination side effect analysis process；It is described according to the medicine name and the disease type, face from what is prestored
Corresponding clinical data is obtained in bed database, comprising:
According to second medicine name, the third medicine name and the disease type, from the clinical data prestored
Corresponding second clinical data is obtained in library；
It is described that clinical data analysis model corresponding with the analysis process is selected according to the analysis process, comprising:
It is selected according to the drug combination side effect analysis process corresponding with the drug combination side effect analysis process
Medication combined side effect analysis model；
It is described by the clinical data analysis model, drug side-effect analysis, packet are carried out to the clinical data got
It includes:
By the medication combined side effect analysis model, drug side-effect point is carried out to the second clinical data got
Analysis.
The operational order includes analysis indexes title in one of the embodiments,；It is described according to the medicine name
With the disease type, corresponding clinical data is obtained from the clinical database prestored, comprising:
According to the medicine name, the disease type and the analysis indexes title, from the clinical database prestored
Obtain corresponding clinical data.
The operational order includes patient's grouping in one of the embodiments,；It is described according to the medicine name and institute
Disease type is stated, corresponding clinical data is obtained from the clinical database prestored, comprising:
It is grouped according to the medicine name, the disease type and the patient, is obtained from the clinical database prestored
Corresponding clinical data.
In one of the embodiments, the method also includes:
According to the medicine name and the disease type, corresponding drug pair is obtained from drug side-effect database and is made
Use data；
The drug side-effect data are compared with the result that the drug side-effect is analyzed, and return to the knot compared
Fruit.
In one of the embodiments, described according to the medicine name and the disease type, from the clinic prestored
After obtaining corresponding clinical data in database, the method also includes:
It is for statistical analysis to the clinical data got according to preset rules, and the result of statistical analysis is returned to end
End, so that the terminal shows the result of the statistical analysis.
A kind of analytical equipment of clinical data, described device include:
Operational order obtains module, and for obtaining the operational order of clinical data analysis, the operational order includes drug
Title, disease type and analysis process；
Clinical data obtains module, is used for according to the medicine name and the disease type, from the clinical data prestored
Corresponding clinical data is obtained in library；
Analysis model selecting module, for selecting clinical data corresponding with the analysis process according to the analysis process
Analysis model；
Clinical data analysis module, for being carried out to the clinical data got by the clinical data analysis model
Drug side-effect analysis, and obtain the result of drug side-effect analysis.
A kind of computer equipment can be run on a memory and on a processor including memory, processor and storage
The step of computer program, the processor realizes method described in any of the above-described embodiment when executing the computer program.
A kind of computer readable storage medium, is stored thereon with computer program, and the computer program is held by processor
The step of method described in any of the above-described embodiment is realized when row.
Analysis method, device, computer equipment and the storage medium of above-mentioned clinical data, by obtaining clinical data analysis
Operational order, and operational order includes medicine name, disease type and analysis process；According to medicine name and disease type,
Corresponding clinical data is obtained from the clinical database prestored；And clinic corresponding with analysis process is selected according to analysis process
Data Analysis Model；To carry out drug side-effect analysis to the clinical data got using clinical data analysis model, obtain
The result analyzed to drug side-effect.The reasonable utilization to clinical data is realized, clinical data in traditional technology is solved and does not have
There is the technical issues of effectively being excavated and utilized.
Detailed description of the invention
Fig. 1 is the applied environment figure of the analysis method of clinical data in one embodiment；
Fig. 2 is the flow diagram of the analysis method of clinical data in one embodiment；
Fig. 3 a is the flow diagram of the analysis method of clinical data in one embodiment；
Fig. 3 b to Fig. 3 d is the partial schematic diagram of clinical data analysis software interface in one embodiment；
Fig. 4 a is the flow diagram of the analysis method of clinical data in one embodiment；
Fig. 4 b to Fig. 4 c is the partial schematic diagram of clinical data analysis software interface in one embodiment；
Fig. 5 a is the flow diagram of the analysis method of clinical data in one embodiment；
Fig. 5 b is the partial schematic diagram of clinical data analysis software interface in one embodiment；
Fig. 6 is the partial schematic diagram of clinical data analysis software interface in one embodiment；
Fig. 7 is the flow diagram of the analysis method of clinical data in one embodiment；
Fig. 8 is the flow diagram of the analysis method of clinical data in one embodiment；
Fig. 9 is the structural block diagram of the analytical equipment of clinical data in one embodiment；
Figure 10 is the internal structure chart of computer equipment in one embodiment.
Specific embodiment
It is with reference to the accompanying drawings and embodiments, right in order to which the objects, technical solutions and advantages of the application are more clearly understood
The application is further elaborated.It should be appreciated that specific embodiment described herein is only used to explain the application, and
It is not used in restriction the application.
The application provides a kind of analysis method of clinical data, can be applied in application environment shown in FIG. 1.Wherein,
Terminal 110 carries out data interaction, data interaction side of the application to terminal 110 and server 120 by network and server 120
Formula is not limited.Terminal 110 is displayed for the operation interface of clinical data analysis software, is connect by operation interface terminal
The operational order of Client-initiated clinical data analysis is received, and operational order is sent to server 120 by terminal 110, then is serviced
Device 120 obtains the operational order of clinical data analysis, which carries medicine name, disease type and analysis process etc.
Information.Server 120 prestores clinical database.Hospital information management system of the data from hospital in clinical database
HIS, Laboratory Information Management System LIMS and other operation systems.Server 120 according to medicine name and disease type,
Corresponding clinical data is obtained from the clinical database prestored；And clinic corresponding with analysis process is selected according to analysis process
Data Analysis Model；To carry out drug side-effect analysis to the clinical data got using clinical data analysis model, obtain
The result analyzed to drug side-effect.The result that drug side-effect is analyzed is returned to terminal 110 by server 120, and terminal receives
To drug side-effect analyze result and shown.Wherein, terminal 110 can be, but not limited to be various personal computers, pen
Remember this computer, smart phone, tablet computer and portable wearable device, server 120 can with independent server or
It is the server cluster of multiple server compositions to realize.It is understood that terminal 110 and server 120 can integrate
Together.
In one embodiment, as shown in Fig. 2, providing a kind of analysis method of clinical data, it is applied in this way
It is illustrated in the server of Fig. 1, comprising the following steps:
S210, the operational order for obtaining clinical data analysis.
Wherein, operational order refers to the instruction for the analysis clinical data that terminal to server is sent.Operational order includes medicine
Name claims, disease type and analysis process.Analysis process refers to analyzing clinical data using biometrical method
Several processes.Specifically, when user needs the clinical data to a certain drug to analyze, user can be by terminal
Application program or webpage input medicine name, the selection disease type and analysis process analyzed, and triggering pair
The operational order is sent to server by the operational order answered, terminal, and server gets the operational order, and the operational order
Carry the information such as medicine name, disease type and analysis process.
S220, according to medicine name and disease type, corresponding clinical data is obtained from the clinical database prestored.
Wherein, to hospital information management system HIS, Laboratory Information Management System LIMS and other operation system
Electronic health record data are acquired, arrange, and are stored in server and form clinical database.Specifically, server receives eventually
The operational order sent is held, operational order carries medicine name and disease type, so that server is according to medicine name and disease
Sick type searches from the clinical database prestored and obtains corresponding clinical data.
S230, clinical data analysis model corresponding with analysis process is selected according to analysis process.
Wherein, clinical data analysis model is the calculation for being analyzed the clinical data got according to operational order
Method model.The corresponding relationship of analysis process Yu clinical data analysis model is prestored in server.Specifically, server receives eventually
The operational order sent is held, operational order carries analysis process, so that server is according to analysis process selection for clinical number
According to the algorithm model of analysis, carried out between drug used and drug side-effect using the algorithm model to clinical data is got
Correlation analysis.
S240, drug side-effect analysis is carried out to the clinical data got by clinical data analysis model, and obtained
The result of drug side-effect analysis.
Wherein, drug side-effect refers to that the pharmacology other than the therapeutic purposes occurred after a certain drug of application for the treatment of amount is made
With.Specifically, server receives the operational order of terminal transmission, is searched according to the operational order and obtains corresponding clinical number
According to also selecting corresponding clinical data analysis model.Using the clinical data analysis model of selection to the clinical number got
According to being analyzed, to excavate drug side-effect, the result of drug side-effect analysis is obtained.
In the present embodiment, by obtaining the operational order of clinical data analysis, and operational order includes medicine name, disease
Type and analysis process；According to medicine name and disease type, corresponding clinical data is obtained from the clinical database prestored；
And clinical data analysis model corresponding with analysis process is selected according to analysis process；To utilize clinical data analysis model pair
The clinical data got carries out drug side-effect analysis, obtains the result of drug side-effect analysis.It realizes to clinical data
Reasonable utilization, solve the technical issues of clinical data is not effectively excavated and utilized in traditional technology.Further,
By the analysis to drug side-effect, binding analysis result provides therapeutic regimen for patient, can be promoted medication reasonability and
Accuracy.
In one embodiment, medicine name includes the first medicine name, and analysis process is single medicine side effect analysis
Process.As shown in Figure 3a, according to medicine name and disease type, corresponding clinical number is obtained from the clinical database prestored
According to, comprising:
S310, according to the first medicine name and disease type, corresponding first is obtained from the clinical database prestored and is faced
Bed data；
Clinical data analysis model corresponding with analysis process is selected according to analysis process, comprising:
S320, according to single medicine side effect analysis process select it is corresponding with single medicine side effect analysis process single
Drug side-effect analysis model；
By clinical data analysis model, drug side-effect analysis is carried out to the clinical data got, comprising:
S330, drug side-effect point is carried out to the first clinical data got by single medicine side effect analysis model
Analysis.
Wherein, single medicine side effect analysis is for analyzing whether the use of a certain certain drug can generate certain clinics
Side effect.Single medicine side effect analysis model is corresponding with single medicine side effect analysis process.If user selects single medicine
Side effect analysis process, server determine the analysis that drug side-effect is carried out using single medicine side effect analysis model.
Specifically, as shown in Figure 3b, terminal shows the operation interface of clinical data analysis software, can by the operation interface
To select disease type.As shown in Figure 3c, the first medicine name and the selection of user's input be can receive by the operation interface
Analysis process.Further, the operation interface of clinical data analysis software is equipped with corresponding operation button, clinical data analysis
The operation interface of software is equipped with " analysis " button, and by triggering the button, user initiates corresponding operational order.The operational order
Carry the first medicine name, disease type and single medicine side effect analysis process.To according to the first medicine name and disease
Sick type obtains corresponding first clinical data from the clinical database prestored, and is analyzed and flowed according to single medicine side effect
Journey selects single medicine side effect analysis model corresponding with single medicine side effect analysis process, and then utilizes the single of selection
Drug side-effect analysis model analyzes the first clinical data got, to excavate drug side-effect, obtains drug
The result of side effect analysis.
Illustratively, single medicine side effect analysis model can be using the assessment medication of Ma Xiusi related coefficient and kidney poison
The algorithm model of the correlation of property.Even user's Selection utilization Ma Xiusi related coefficient (Matthews Correlation
Coefficient, MCC) it is analyzed.As shown in Figure 3d, last analysis result is shown as the relevant calculating of Ma Xiusi coefficient
As a result, wherein SE represents susceptibility, and SP represents specificity, and Q represents accuracy, and Pvalue represents assumed value, MCC Ma Xiusi
Related coefficient.
In one embodiment, medicine name includes the second medicine name and third medicine name, and analysis process is drug
It is combined side effect analysis process.As shown in fig. 4 a, it according to medicine name and disease type, is obtained from the clinical database prestored
Corresponding clinical data, comprising:
S410, according to the second medicine name, third medicine name and disease type, obtained from the clinical database prestored
Corresponding second clinical data；
Clinical data analysis model corresponding with analysis process is selected according to analysis process, comprising:
S420, drug corresponding with drug combination side effect analysis process is selected according to drug combination side effect analysis process
Joint side effect analysis model；
By clinical data analysis model, drug side-effect analysis is carried out to the clinical data got, comprising:
S430, by medication combined side effect analysis model, drug side-effect is carried out to the second clinical data got
Analysis.
Wherein, whether can be generated whether the combination for analyzing certain two kinds of certain drug is analyzed in drug combination side effect certain
Clinical side effects.Second medicine name can be Chinese medicine title, be also possible to Western medicine title.Likewise, third medicine name can
To be Chinese medicine title, it is also possible to Western medicine title.As shown in Figure 4 b, when the second medicine name is Chinese medicine title, third medication name
Title is Western medicine title, and it is certain whether drug combination side effect analysis can generate whether analyzing the combination of certain Western medicine and certain class Chinese medicine
Clinical side effects.Drug combination side effect analysis model is corresponding with drug combination side effect analysis process.If user selects drug
It is combined side effect analysis process, server determines the analysis that drug side-effect is carried out using drug combination side effect analysis model.
Specifically, terminal shows that the operation interface of clinical data analysis software as shown in Figure 3b can by the operation interface
It needs to analyze disease type with selection.As shown in Figure 3c, user can trigger " block analysis (two kinds of drugs) " or " component point
Analyse (Chinese and Western medicine combination analysis) " to select drug combination side effect analysis process.It as illustrated in fig. 4 c, can be with by the operation interface
Receive the second medicine name and third medicine name of user's input.Further, user is initiated by triggering " analysis " button
Corresponding operational order.The operational order carries the second medicine name, third medicine name, disease type and drug combination pair
Function analysis process.Thus according to the second medicine name, third medicine name and disease type, from the clinical database prestored
Corresponding second clinical data is obtained, and is flowed according to the selection of drug combination side effect analysis process and drug combination side effect analysis
Journey corresponding medication combined side effect analysis model, and then using the drug combination side effect analysis model of selection to getting
Second clinical data is analyzed, and to excavate drug side-effect, obtains the result of drug side-effect analysis.
It is understood that medication combined side effect analysis model is using mature statistical algorithms assessment drug combination
With the algorithm model of a certain drug side-effect correlation, for example, to get clinical data sample whether meet normal distribution into
Row judgement, can use variance analysis if getting clinical data sample and meeting normal distribution, if getting clinical data sample
Originally the u-test that normal distribution uses non-parametric test is not met, is known in skilled person, details are not described herein.
In one embodiment, operational order includes analysis indexes title.According to medicine name and disease type, from prestoring
Clinical database in obtain corresponding clinical data, comprising: according to medicine name, disease type and analysis indexes title, from
Corresponding clinical data is obtained in the clinical database prestored.
Wherein, as shown in Figure 5 a, terminal shows the operation interface of clinical data analysis software, and analysis indexes include examining to refer to
Mark, nursing index and treatment final result.Specifically, analysis indexes title, analysis indexes can choose by operation interface user
Title can be verification index analysis, is also possible to nursing index analysis, can also be treatment outcome.When server receives
When the operational order that terminal is sent, operational order carries medicine name, disease type and analysis indexes title, thus server
It is searched from the clinical database prestored according to medicine name, disease type and analysis indexes title and obtains corresponding clinical number
According to.
It should be noted that the application can provide 60 detection and analysis indexs and 10 Nursing Analysis indexs.Including normal
The indexs such as albumin, blood platelet, blood pressure, weight.The foundation of clinical database the following steps are included: from the HIS of hospital and
The electronic health record data that LIMS is obtained, handle the electronic health record data of acquisition.The treatment process of data includes missing values
Processing, according to circumstances using two methods of rejecting missing values or filling missing values.Fill the big portion that missing values utilize data with existing
Point information predicts missing information.Missing values processing after, carry out data selection, delete redundant attributes and in clinical data
The little attribute of heart relationship.It is final to be saved using unified format, such as csv format.Clinical database includes Patient
Table, Order information table, Labtest Index for examination information table, Diagnosis table and Vital table.Wherein, Patient table can be with
The information such as patient gender, date of birth, medical record number, admission number, admission date and discharge date are provided.Order information table can be with
Medicining condition including patient during all previous be hospitalized.Labtest Index for examination information table can provide patient during being hospitalized
All information inside checked every time, the time of title, detection including Testing index and the result of detection.Diagnosis table can
To include the relevant information of all previous diagnosis being hospitalized of patient.Vital table may include the information of some nursing indexes.
In one embodiment, operational order includes patient's grouping.According to medicine name and disease type, face from what is prestored
Corresponding clinical data is obtained in bed database, comprising: is grouped according to medicine name, disease type and patient, is faced from what is prestored
Corresponding clinical data is obtained in bed database.
Wherein, terminal shows the operation interface of clinical data analysis software.As shown in Figure 4 b, operation interface shows patient point
Group " Group1 ", " Group2, patient's grouping are also known as patient's grouping, can such as gender (male, female), year according to actual needs
Age section, whether perform the operation etc. is grouped.Specifically, patient's grouping can choose by operation interface user.Work as server
When receiving the operational order that terminal is sent, operational order carries medicine name, disease type and patient's grouping, thus server
It is searched from the clinical database prestored according to medicine name, disease type and patient grouping and obtains corresponding clinical data.
In one embodiment, as shown in Figure 5 b, this method is further comprising the steps of:
S510, according to medicine name and disease type, corresponding drug side-effect is obtained from drug side-effect database
Data.
S520, drug side-effect data are compared with the result that drug side-effect is analyzed, and return to comparison result.
Wherein, from SIDER (Side Effect Resource), FAERS (FDA Adverse Event Reporting
System) databases downloading data and the cleaning treatment such as obtain the information of drug side-effect, generate drug side-effect database.
Illustratively, database sharing uses Node.js+Express+MongoDB frame.Node.js operates in server-side
JavaScript, is the JavaScript running environment based on Chrome V8 engine, and Node.js has used an event
It drives, the model of non-block type I/O, the package manager npm of Node.js is the global maximum open source library ecosystem.Express
It is extremely simple, the flexible web application development framework based on Node.js platform, it provides a series of powerful characteristics, helps
We create various Web and mobile device application.Among the Connect of HTTP quick method and arbitrary arrangement combination abundant
Part, so that creation is healthy and strong, the API of close friend becomes not only quickly but also simple.Express does not carry out two to the existing characteristic of Node.js
It is secondary abstract, Web is only extended on it using required basic function.MongoDB is a kind of non-relational database, no
The table structure for needing to pre-define fixation, eliminates relation property, is very easy to extension, it may be convenient to supplement increased drug
Disease relationship information.Specifically, Node.js is installed, configures Node.js in PATH environmental variance, creates database
Express project uploads in item code to svn Version Control device, and records link, installs MongoDB database, then may be used
To import data.
Specifically, server prestores drug side-effect database.Server receives the medicine name that operational order carries
And disease type obtains corresponding drug side-effect number according to medicine name and disease type from drug side-effect database
According to.The drug side-effect data that will acquire are compared with the result that drug side-effect is analyzed, and compare to terminal return
As a result.In the present embodiment, by being combined to drug side-effect database and clinical data analysis, not only realize to clinic
The monitoring of medication side effect reaction, and it can be found that the new application of drug, realize drug reorientation.
In one embodiment, it according to medicine name and disease type, obtains and corresponds to from the clinical database prestored
Clinical data after, this method further include: for statistical analysis to the clinical data got according to preset rules, and return
The result of statistical analysis is to terminal, so that the result of terminal display statistical analysis.
Specifically, the statistical analysis of clinical data can carry out clinical data according to preset rules, such as Gender, year
Age section, whether surgery situation, treatment final result situation (cure, is invalid, improvement, death etc.).The statistical analysis of clinical data
Can be statistics, patient uses the number and entirety medication duration of certain drug within the scope of certain patient in one section of preset time
Or statistics uses classification of drug situation.The statistical analysis of clinical data is also possible to clinical medicine side effect statistical analysis, mainly
Between analysis group and interior patient is organized after certain drug use, influence of the drug to Testing index and treatment final result variation.Finally, it takes
The result of statistical analysis is back to terminal by device of being engaged in so that terminal display statistical analysis as a result, Chinese and Western medicine as shown in FIG. 6 makes
Use situation.
In one embodiment, the application provides a kind of analysis method of clinical data.As shown in fig. 7, this method includes
Following steps:
S702, the operational order for obtaining clinical data analysis, operational order include the first medicine name, disease type, divide
Analyse process, analysis indexes title and patient's grouping；Wherein, analysis process is single medicine side effect analysis process；
S704, it is grouped according to the first medicine name, disease type, analysis indexes title and patient, from the clinical number prestored
According to obtaining corresponding clinical data in library；
It is S706, for statistical analysis to the clinical data got according to preset rules, and return to the result of statistical analysis
To terminal, so that the result of terminal display statistical analysis；
S708, according to single medicine side effect analysis process select it is corresponding with single medicine side effect analysis process single
Drug side-effect analysis model；
S710, drug side-effect analysis is carried out to the clinical data got by single medicine side effect analysis model,
Obtain the result of drug side-effect analysis；
S712, according to medicine name and disease type, corresponding drug side-effect is obtained from drug side-effect database
Data；
S714, drug side-effect data are compared with the result that drug side-effect is analyzed, and return to comparison result.
In one embodiment, the application provides a kind of analysis method of clinical data.As shown in figure 8, this method includes
Following steps:
S802, the operational order for obtaining clinical data analysis, operational order include the second medicine name, third medication name
Title, disease type, analysis process, analysis indexes title and patient's grouping；Wherein, analysis process is drug combination side effect analysis
Process；
S804, it is grouped according to the second medicine name, third medicine name, disease type, analysis indexes title and patient, from
Corresponding clinical data is obtained in the clinical database prestored；
It is S806, for statistical analysis to the clinical data got according to preset rules, and return to the result of statistical analysis
To terminal, so that the result of terminal display statistical analysis；
S808, drug corresponding with drug combination side effect analysis process is selected according to drug combination side effect analysis process
Joint side effect analysis model；
S810, drug side-effect analysis is carried out to the clinical data got by medication combined side effect analysis model.
S812, according to medicine name and disease type, corresponding drug side-effect is obtained from drug side-effect database
Data；
S814, drug side-effect data are compared with the result that drug side-effect is analyzed, and return to comparison result.
It should be understood that although each step in above-mentioned flow chart is successively shown according to the instruction of arrow, this
A little steps are not that the inevitable sequence according to arrow instruction successively executes.Unless expressly state otherwise herein, these steps
It executes there is no the limitation of stringent sequence, these steps can execute in other order.Moreover, in above-mentioned flow chart at least
A part of step may include that perhaps these sub-steps of multiple stages or stage are not necessarily in same a period of time to multiple sub-steps
Quarter executes completion, but can execute at different times, the execution in these sub-steps or stage be sequentially also not necessarily according to
Secondary progress, but in turn or can replace at least part of the sub-step or stage of other steps or other steps
Ground executes.
In one embodiment, as shown in figure 9, providing a kind of analytical equipment 900 of clinical data.Returning apparatus includes:
Operational order obtains module 910, and for obtaining the operational order of clinical data analysis, operational order includes medication name
Title, disease type and analysis process；
Clinical data obtains module 920, for being obtained from the clinical database prestored according to medicine name and disease type
Take corresponding clinical data；
Analysis model selecting module 930, for selecting clinical data analysis corresponding with analysis process according to analysis process
Model；
Clinical data analysis module 940, for carrying out medicine to the clinical data got by clinical data analysis model
Object side effect analysis, obtains the result of drug side-effect analysis.
The specific of analytical equipment about clinical data limits the analysis method that may refer to above for clinical data
Restriction, details are not described herein.Modules in the analytical equipment of above-mentioned clinical data can be fully or partially through software, hard
Part and combinations thereof is realized.Above-mentioned each module can be embedded in the form of hardware or independently of in the processor in computer equipment,
It can also be stored in a software form in the memory in computer equipment, execute the above modules in order to which processor calls
Corresponding operation.
In one embodiment, a kind of computer equipment is provided, which can be terminal, internal structure
Figure can be as shown in Figure 10.The computer equipment includes the processor connected by system bus, memory, network interface, shows
Display screen and input unit.Wherein, the processor of the computer equipment is for providing calculating and control ability.The computer equipment
Memory includes non-volatile memory medium, built-in storage.The non-volatile memory medium is stored with operating system and computer
Program.The built-in storage provides environment for the operation of operating system and computer program in non-volatile memory medium.The meter
The network interface for calculating machine equipment is used to communicate with external terminal by network connection.When the computer program is executed by processor
To realize a kind of analysis method of clinical data.The display screen of the computer equipment can be liquid crystal display or electric ink
Display screen, the input unit of the computer equipment can be the touch layer covered on display screen, be also possible to outside computer equipment
Key, trace ball or the Trackpad being arranged on shell can also be external keyboard, Trackpad or mouse etc..
It will be understood by those skilled in the art that structure shown in Figure 10, only part relevant to application scheme
The block diagram of structure, does not constitute the restriction for the computer equipment being applied thereon to application scheme, and specific computer is set
Standby may include perhaps combining certain components or with different component layouts than more or fewer components as shown in the figure.
In one embodiment, a kind of computer equipment is provided, including memory, processor and storage are on a memory
And the computer program that can be run on a processor, processor realize the method step in above-described embodiment when executing computer program
Suddenly.
In one embodiment, a kind of computer readable storage medium is provided, computer program is stored thereon with, is calculated
Machine program realizes the method and step in above-described embodiment when being executed by processor.
Those of ordinary skill in the art will appreciate that realizing all or part of the process in above-described embodiment method, being can be with
Relevant hardware is instructed to complete by computer program, the computer program can be stored in a non-volatile computer
In read/write memory medium, the computer program is when being executed, it may include such as the process of the embodiment of above-mentioned each method.Wherein,
To any reference of memory, storage, database or other media used in each embodiment provided herein,
Including non-volatile and/or volatile memory.Nonvolatile memory may include read-only memory (ROM), programming ROM
(PROM), electrically programmable ROM (EPROM), electrically erasable ROM (EEPROM) or flash memory.Volatile memory may include
Random access memory (RAM) or external cache.By way of illustration and not limitation, RAM is available in many forms,
Such as static state RAM (SRAM), dynamic ram (DRAM), synchronous dram (SDRAM), double data rate sdram (DDRSDRAM), enhancing
Type SDRAM (ESDRAM), synchronization link (Synchlink) DRAM (SLDRAM), memory bus (Rambus) direct RAM
(RDRAM), direct memory bus dynamic ram (DRDRAM) and memory bus dynamic ram (RDRAM) etc..
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
The several embodiments of the application above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the concept of this application, various modifications and improvements can be made, these belong to the protection of the application
Range.Therefore, the scope of protection shall be subject to the appended claims for the application patent.
Claims (10)
1. a kind of analysis method of clinical data, which is characterized in that the described method includes:
The operational order of clinical data analysis is obtained, the operational order includes medicine name, disease type and analysis process；
According to the medicine name and the disease type, corresponding clinical data is obtained from the clinical database prestored；
Clinical data analysis model corresponding with the analysis process is selected according to the analysis process；
By the clinical data analysis model, drug side-effect analysis is carried out to the clinical data got, and obtain drug
The result of side effect analysis.
2. the method according to claim 1, wherein the medicine name include the first medicine name, described point
Analysis process is single medicine side effect analysis process；It is described according to the medicine name and the disease type, face from what is prestored
Corresponding clinical data is obtained in bed database, comprising:
According to first medicine name and the disease type, it is clinical that corresponding first is obtained from the clinical database prestored
Data；
It is described that clinical data analysis model corresponding with the analysis process is selected according to the analysis process, comprising:
It is selected according to the single medicine side effect analysis process corresponding single with the single medicine side effect analysis process
Drug side-effect analysis model；
The clinical data progress drug side-effect analysis by the clinical data analysis model, to getting, comprising:
By the single medicine side effect analysis model, drug side-effect analysis is carried out to the first clinical data got.
3. the method according to claim 1, wherein the medicine name includes the second medicine name and third medicine
Name claims, and the analysis process is drug combination side effect analysis process；It is described according to the medicine name and the disease class
Type obtains corresponding clinical data from the clinical database prestored, comprising:
According to second medicine name, the third medicine name and the disease type, from the clinical database prestored
Obtain corresponding second clinical data；
It is described that clinical data analysis model corresponding with the analysis process is selected according to the analysis process, comprising:
Drug corresponding with the drug combination side effect analysis process is selected according to the drug combination side effect analysis process
Joint side effect analysis model；
The clinical data progress drug side-effect analysis by the clinical data analysis model, to getting, comprising:
By the medication combined side effect analysis model, drug side-effect analysis is carried out to the second clinical data got.
4. the method according to claim 1, wherein the operational order includes analysis indexes title；Described
According to the medicine name and the disease type, corresponding clinical data is obtained from the clinical database prestored, comprising:
According to the medicine name, the disease type and the analysis indexes title, obtained from the clinical database prestored
Corresponding clinical data.
5. the method according to claim 1, wherein the operational order includes patient's grouping；It is described according to institute
Medicine name and the disease type are stated, corresponding clinical data is obtained from the clinical database prestored, comprising:
It is grouped according to the medicine name, the disease type and the patient, obtains and correspond to from the clinical database prestored
Clinical data.
6. the method according to claim 1, wherein the method also includes:
According to the medicine name and the disease type, corresponding drug side-effect number is obtained from drug side-effect database
According to；
The drug side-effect data are compared with the result that the drug side-effect is analyzed, and return to comparison result.
7. method according to any one of claims 1 to 6, which is characterized in that described according to the medicine name and institute
Disease type is stated, after obtaining corresponding clinical data in the clinical database prestored, the method also includes:
It is for statistical analysis to the clinical data got according to preset rules, and return to the result of statistical analysis to terminal, with
The terminal is set to show the result of the statistical analysis.
8. a kind of analytical equipment of clinical data, which is characterized in that described device includes:
Operational order obtains module, for obtaining the operational order of clinical data analysis, the operational order include medicine name,
Disease type and analysis process；
Clinical data obtains module, is used for according to the medicine name and the disease type, from the clinical database prestored
Obtain corresponding clinical data；
Analysis model selecting module, for selecting clinical data analysis corresponding with the analysis process according to the analysis process
Model；
Clinical data analysis module, for carrying out drug to the clinical data got by the clinical data analysis model
Side effect analysis, and obtain the result of drug side-effect analysis.
9. a kind of computer equipment including memory, processor and stores the meter that can be run on a memory and on a processor
Calculation machine program, which is characterized in that the processor realizes any one of claims 1 to 7 institute when executing the computer program
The step of stating method.
10. a kind of computer readable storage medium, is stored thereon with computer program, which is characterized in that the computer program
The step of method described in any one of claims 1 to 7 is realized when being executed by processor.
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Application publication date: 20190927 |