CN110279498A - A kind of staggered floor overlapped 3D printing orthopaedics implant and preparation method - Google Patents

A kind of staggered floor overlapped 3D printing orthopaedics implant and preparation method Download PDF

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Publication number
CN110279498A
CN110279498A CN201910665530.0A CN201910665530A CN110279498A CN 110279498 A CN110279498 A CN 110279498A CN 201910665530 A CN201910665530 A CN 201910665530A CN 110279498 A CN110279498 A CN 110279498A
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China
Prior art keywords
printing
layer
basic unit
parallel fibers
orthopaedics implant
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CN201910665530.0A
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Chinese (zh)
Inventor
陈重光
郑炜
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Tongguang (kunshan) Biotechnology Co Ltd
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Tongguang (kunshan) Biotechnology Co Ltd
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Priority to CN201910665530.0A priority Critical patent/CN110279498A/en
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Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10Processes of additive manufacturing
    • B29C64/106Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
    • B29C64/118Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using filamentary material being melted, e.g. fused deposition modelling [FDM]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/30Auxiliary operations or equipment
    • B29C64/386Data acquisition or data processing for additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/30Auxiliary operations or equipment
    • B29C64/386Data acquisition or data processing for additive manufacturing
    • B29C64/393Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00Processes of additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00Data acquisition or data processing for additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00Data acquisition or data processing for additive manufacturing
    • B33Y50/02Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2002/30985Designing or manufacturing processes using three dimensional printing [3DP]

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Prostheses (AREA)

Abstract

The invention discloses a kind of staggered floor overlapped 3D printing orthopaedics implants and preparation method thereof.The shape of staggered floor overlapped 3D printing orthopaedics implant is cylindrical body, is successively stacked by several layers basic unit, and it is nonparallel between the parallel fibers of neighboring unit cells that the basic unit, which is the planar structure that parallel and unbroken fiber is constituted,.It is preferred that the differential seat angle of the parallel fibers of each neighbouring basic unit is 120 ° clockwise or counterclockwise, internal hexagon micropore is formd.It is hexagon micropore inside staggered floor of the present invention overlapped implant structure, is perforation up and down, and there are the micropores of perforation for left and right cavity wall, and the nutriments such as blood vessel is allowed inwardly to convey nutrient by left and right cavity wall, the implant structure bioactivity is higher.

Description

A kind of staggered floor overlapped 3D printing orthopaedics implant and preparation method
Technical field
The invention belongs to medical material tech fields, and in particular to a kind of staggered floor overlapped 3D printing orthopaedics implant and take Connect method.
Background technique
3D printing technique is by Computer Design as a kind of novel one of rapid shaping and Rapid Manufacturing Technology Threedimensional model is blueprint, by RP software hierarchy, in the way of laser beam, hot melt etc. by metal powder, ceramic powders, plastics, Equal special materials are successively accumulated, and final superposition molding manufactures physical model.
Ideal artificial bone structure is looked in design, to repair it is clinical because caused by a variety of causes bone defect be always orthopaedics neck Study very active project in domain.3D printing porous implant is considered having extraordinary therapeutic effect in Orthopedic Clinical, existing Have and has related to specific bone structure, such as hipbone in technology, the big bone structure such as shin bone.But for small orthopaedics filler, also There are development.
Biology 3D printing orthopaedics implant internal structure studied both at home and abroad at present is mainly quadrangle or triangle, to phase It closes technical data to research and analyse, it is found that cellular regular hexagon and bone tissue are the most close, and mechanical property is optimal, but existing The left and right face of technology hexagonal structure cannot achieve perforation, and the nutriments such as blood vessel can not inwardly be conveyed by left and right cavity wall supports Point, cause the structural implants bioactivity lower.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of staggered floor of 3D printing for orthopaedics implant overlap joints to tie Structure, internal formation honeycomb hexahedron improve the life of implantation material to realize that implantation material internal structure all penetrates through up and down Object activity.
A kind of overlapped in order to solve the above technical problems, the present invention provides staggered floor 3D printing orthopaedics implant, shape are Cylindrical body is successively stacked by several layers basic unit, and the basic unit is one that parallel and unbroken fiber is constituted Planar structure, be between the parallel fibers of neighboring unit cells it is nonparallel, that is, have certain angle poor.
Preferably, the planar structure periphery is circle.
Preferably, later layer basic unit parallel fibers is using the differential seat angle with preceding layer basic unit parallel fibers as up time 120 ° of directions of needle are successively stacked;At least every three layers of basic unit stacks to form internal hexagon micropore.
Preferably, later layer basic unit parallel fibers is using the differential seat angle with preceding layer basic unit parallel fibers as the inverse time 120 ° of directions of needle are successively stacked;At least every three layers of basic unit stacks to form internal hexagon micropore.
Preferably, there is the overlapping of 0.06~0.14mm between each neighbouring basic unit.
The present invention also provides the manufacturing methods of staggered floor overlapped 3D printing orthopaedics implant, comprising the following steps:
(1) model is established in layering, and every layer of basic unit is parallel and interconnects the plane that unbroken fiber is constituted, fine Diameter 0.2-0.6mm is tieed up, there is certain angle between the parallel fibers of neighboring unit cells;
(2) model of foundation is summed and exports STL model, be sliced that form printer identifiable by software Gcode formatted file;Wherein slicing parameter is provided that print speed: 1-20mm/s;Rotation speed of the fan: 80%-100%;Path Planning: every layer of continuous printing shaping, 0.2-0.6mm round-corner transition between fiber, and first layer basic unit was removed, it prints At any one layer, spray head is all reference with following one layer of basic unit, is printed with certain angle path movement and continuously;Printable layer It is thick: first layer 0.1-0.3mm, other layer of 0.15-0.4mm;There is 0.06-0.14mm overlapping between neighbouring unit;Printing After the every printing of machine completes one layer, substrate decline 0.3mm simultaneously carries out next layer of printing;
(3) print procedure controls --- printing environment temperature: 0-25 DEG C;Print temperature: 60-100 DEG C;Shaping substrate temperature Degree: 30-45 DEG C;
(4) after the completion of printing, substrate temperature is adjusted downward to 0-15 DEG C, removes model after cooling.
In step (1), the angle between the parallel fibers of neighboring unit cells is 120 °.
In step (2), when printing any one layer, spray head is all reference with following one layer of basic unit, with clockwise or inverse 120 ° of angle paths of clockwise are mobile and continuously print, the internal positive six faces shape micropore of every three layers of formation.
The present invention is researched and analysed according to correlation technique data, it is found that cellular regular hexagon and bone tissue are the most close, And mechanical property is optimal.It is hexagon micropore inside staggered floor of the present invention overlapped implant structure, is perforation up and down, and left and right There are the micropores of perforation for cavity wall, and the nutriments such as blood vessel is allowed inwardly to convey nutrient by left and right cavity wall, the implantation material knot Structure bioactivity is higher.
Detailed description of the invention
The invention will be further described with reference to the accompanying drawings and embodiments:
Fig. 1 is staggered floor of the invention overlapped 3D printing orthopaedics implant.
Fig. 2 is several basic cell structure schematic diagrames and partial enlarged view of 3D printing orthopaedics implant of the invention.
Wherein, 1 is 3D printing orthopaedics implant, and 11 be first layer basic unit, and 12 be second layer basic unit, and 13 be the Three layers of basic unit, 131 be the parallel fibers for constituting third layer basic unit, and 14 be internal hexagon micropore.
Specific embodiment
In order to understand the technical characteristic and practical effect of invention in detail, and can implement according to the content of specification, Further with preferred embodiment as indicated in the drawings.
A kind of staggered floor of the invention as shown in Figure 1 overlapped 3D printing orthopaedics implant 1, shape are cylinder, It is successively stacked by several layers basic unit, the basic unit is the planar structure that parallel fibers is arranged to make up, adjacent Be between the parallel fibers of basic unit it is nonparallel, that is, have certain angle it is poor.
Fig. 2 is that one embodiment schematic diagram of several basic cell structures of 3D printing orthopaedics implant of the invention and part are put Big figure, it can be seen that the 3D printing orthopaedics implant of the present embodiment it include three basic units: 11 be that first layer is substantially single Member, 12 be second layer basic unit, and 13 be third layer basic unit, and each basic unit is what parallel fibers was arranged to make up One planar structure, the planar structure periphery are circle;And parallel fibers is non-disconnection, that is, is connected with each other, and is continuous for one Fiber such as constitutes the parallel fibers 131 of third layer basic unit 13.
And from the preferred embodiment as it can be seen that 12 parallel fibers of second layer basic unit is with parallel with first layer basic unit 11 The differential seat angle of fiber is that 120 ° of directions counterclockwise are stacked, and 13 parallel fibers of third layer basic unit is with substantially single with the second layer The differential seat angle of first 12 parallel fibers is that 120 ° of directions counterclockwise are stacked, and so successively stacks, ultimately forms six internal sides Shape micropore.Certainly, in another embodiment, it can be and successively stack clockwise.The inside of structure of the invention is six side of honeycomb Shape structure is built using the dislocation of multilayer battlement, is dislocatedly distributed between every layer of bracket, and every three layers of basic unit forms one completely Regular hexagon, ensure that the permeability of cavity wall, and be conducive to cell, blood vessel from cavity wall ingrowing, guarantee the implantation material Bioactivity.
In a preferred embodiment of the present invention, there is the weight of 0.06~0.14mm between each neighbouring basic unit It is folded.I.e. in printing, designs each basic unit and connect between each other, form an entirety.And it is preferably each substantially single The height of member is between 0.2-0.6mm.
Embodiment 1
The manufacturing method of 3D printing orthopaedics implant, comprising the following steps:
(1) model is established in layering, and every layer of basic unit is parallel and interconnects the plane that unbroken fiber is constituted, fine Diameter 0.35mm is tieed up, is 120 ° of angles between the parallel fibers of neighboring unit cells;
(2) model of foundation is summed and exports STL model, be sliced that form printer identifiable by software Gcode formatted file;Wherein slicing parameter is provided that print speed: 1-20mm/s;Rotation speed of the fan: 80%-100%;Path Planning: every layer of continuous printing shaping, 0.3mm round-corner transition between fiber, and first layer basic unit was removed, printing is any At one layer, spray head is all reference with following one layer of basic unit, and 120 ° of angle paths are mobile in a clockwise direction and continuously print, The internal positive six faces shape micropore of every three layers of formation;Print thickness: first layer 0.2mm, other layer of 0.25mm;Neighbouring unit it Between have 0.08mm overlapping;After the every printing of printer completes one layer, substrate decline 0.3mm simultaneously carries out next layer of printing, prevents spray head Scratch the model printed;
(3) print procedure controls --- printing environment temperature: 15 DEG C;Print temperature: 75 DEG C;Shaping substrate temperature: 30 DEG C;
(4) after the completion of printing, substrate temperature is adjusted downward to 15 DEG C, waits 5min, when substrate temperature drops to 15 DEG C or less, Model is removed with tweezers.
Embodiment 2
The manufacturing method of 3D printing orthopaedics implant, comprising the following steps:
(1) model is established in layering, and every layer of basic unit is parallel and interconnects the plane that unbroken fiber is constituted, fine Diameter 0.2-0.6mm is tieed up, is 120 ° of angles between the parallel fibers of neighboring unit cells;
(2) model of foundation is summed and exports STL model, be sliced that form printer identifiable by software Gcode formatted file;Wherein slicing parameter is provided that print speed: 1-20mm/s;Rotation speed of the fan: 80%-100%;Path Planning: every layer of continuous printing shaping, 0.2-0.6mm round-corner transition between fiber, and first layer basic unit was removed, it prints At any one layer, spray head is all reference with following one layer of basic unit, and 120 ° of angle paths are mobile and continuous in a counterclockwise direction Primary printing, the internal positive six faces shape micropore of every three layers of formation;Print thickness: first layer 0.3mm, other layer of 0.4mm;It is neighbouring Unit between have 0.13mm overlapping;After the every printing of printer completes one layer, substrate decline 0.3mm simultaneously carries out next layer of printing, Prevent spray head from scratching the model printed;
(3) print procedure controls --- printing environment temperature: 25 DEG C;Print temperature: 85 DEG C;Shaping substrate temperature: 45 DEG C;
(4) after the completion of printing, substrate temperature is adjusted downward to 10 DEG C, waits 06min, substrate temperature drops to 15 DEG C or less When, model is removed with tweezers.
The above is only the preferred embodiment of the present invention, is not intended to limit the present invention in any form, Ren Hesuo Belong in technical field and have usually intellectual, if without departing from the scope of the technical features of the present invention, utilizing institute of the present invention The equivalent embodiment that locally changes or modify made by technology contents is disclosed, in the range of still falling within the technology of the present invention feature.

Claims (10)

1. a kind of staggered floor overlapped 3D printing orthopaedics implant, which is characterized in that its shape is cylindrical body, substantially single by several layers Member successively stacks, and the basic unit is the planar structure that parallel and unbroken fiber is constituted, neighboring unit cells Parallel fibers between be nonparallel.
2. 3D printing orthopaedics implant according to claim 1, which is characterized in that the planar structure periphery is circle.
3. 3D printing orthopaedics implant according to claim 1, which is characterized in that later layer basic unit parallel fibers with Differential seat angle with preceding layer basic unit parallel fibers is that 120 ° of directions clockwise are successively stacked.
4. 3D printing orthopaedics implant according to claim 1, which is characterized in that later layer basic unit parallel fibers with Differential seat angle with preceding layer basic unit parallel fibers is that 120 ° of directions counterclockwise are successively stacked.
5. 3D printing orthopaedics implant according to claim 3 or 4, which is characterized in that at least every three layers of basic unit heap Hexagon micropore inside folded formation.
6. 3D printing orthopaedics implant according to claim 1, which is characterized in that each neighbouring basic unit it Between have the overlapping of 0.06~0.14mm.
7. the manufacturing method of staggered floor described in claim 1 overlapped 3D printing orthopaedics implant, comprising the following steps:
(1) model is established in layering, and every layer of basic unit is parallel and interconnects the plane that unbroken fiber is constituted, and fiber is straight Diameter 0.2-0.6mm has certain angle between the parallel fibers of neighboring unit cells;
(2) model of foundation is summed and exports STL model, be sliced to form the identifiable gcode of printer by software Formatted file;Wherein slicing parameter is provided that print speed: 1-20mm/s;Rotation speed of the fan: 80%-100%;Path planning: Every layer of continuous printing shaping, 0.2-0.6mm round-corner transition between fiber, and first layer basic unit was removed, printing is any At one layer, spray head is all reference with following one layer of basic unit, is printed with certain angle path movement and continuously;Print thickness: First layer 0.1-0.3mm, other layer of 0.15-0.4mm;There is 0.06-0.14mm overlapping between neighbouring unit;Printer is every After printing completes one layer, substrate decline 0.3mm simultaneously carries out next layer of printing;
(3) print procedure controls --- printing environment temperature: 0-25 DEG C;Print temperature: 60-100 DEG C;Shaping substrate temperature: 30- 45℃;
(4) after the completion of printing, substrate temperature is adjusted downward to 0-15 DEG C, removes model after cooling.
8. manufacturing method according to claim 7, which is characterized in that in step (1), the parallel fibers of neighboring unit cells Between angle be 120 °.
9. manufacturing method according to claim 7, which is characterized in that in step (2), when printing any one layer, spray head is all It is reference with following one layer of basic unit, 120 ° of angle paths are mobile in a clockwise direction and continuously print, in every three layers of formation The positive six faces shape micropore in portion.
10. manufacturing method according to claim 7, which is characterized in that in step (2), when printing any one layer, spray head is all It is reference with following one layer of basic unit, 120 ° of angle paths are mobile in a counterclockwise direction and continuously print, in every three layers of formation The positive six faces shape micropore in portion.
CN201910665530.0A 2019-07-23 2019-07-23 A kind of staggered floor overlapped 3D printing orthopaedics implant and preparation method Pending CN110279498A (en)

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CN112008074A (en) * 2020-09-03 2020-12-01 苏州复浩三维科技有限公司 3D printing method and device applied to metal material

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CN112008074B (en) * 2020-09-03 2021-04-30 苏州复浩三维科技有限公司 3D printing method and device applied to metal material

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