CN110279436B - Vaginal microecological specimen collector - Google Patents
Vaginal microecological specimen collector Download PDFInfo
- Publication number
- CN110279436B CN110279436B CN201910233034.8A CN201910233034A CN110279436B CN 110279436 B CN110279436 B CN 110279436B CN 201910233034 A CN201910233034 A CN 201910233034A CN 110279436 B CN110279436 B CN 110279436B
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- China
- Prior art keywords
- opening
- sleeve
- sampling
- vaginal
- sliding
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- 238000005070 sampling Methods 0.000 claims abstract description 45
- 230000000149 penetrating effect Effects 0.000 claims 1
- 210000001215 vagina Anatomy 0.000 abstract description 17
- 244000005700 microbiome Species 0.000 abstract description 5
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 description 10
- 229920000742 Cotton Polymers 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 206010046914 Vaginal infection Diseases 0.000 description 3
- 201000008100 Vaginitis Diseases 0.000 description 3
- 230000007547 defect Effects 0.000 description 3
- 208000035475 disorder Diseases 0.000 description 3
- 239000002504 physiological saline solution Substances 0.000 description 3
- 241001391944 Commicarpus scandens Species 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 108020004465 16S ribosomal RNA Proteins 0.000 description 1
- 208000029082 Pelvic Inflammatory Disease Diseases 0.000 description 1
- 208000006399 Premature Obstetric Labor Diseases 0.000 description 1
- 206010036600 Premature labour Diseases 0.000 description 1
- 208000006374 Uterine Cervicitis Diseases 0.000 description 1
- 206010056530 Vulvovaginal pruritus Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 206010008323 cervicitis Diseases 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000012165 high-throughput sequencing Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 208000026440 premature labor Diseases 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000019206 urinary tract infection Diseases 0.000 description 1
- 210000003905 vulva Anatomy 0.000 description 1
- 238000012070 whole genome sequencing analysis Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B2010/0074—Vaginal or cervical secretions
Abstract
The invention discloses a vaginal microecological specimen collector which comprises an outer sleeve, a middle sleeve, an inner sleeve and a sampling rod which are sequentially matched from outside to inside. The device has a simple structure, can be quickly assembled and is convenient to collect. The collector capable of accurately collecting the micro-ecological sample in the middle section of the vagina is formed through the matching connection of the components, the collected sample cannot be polluted by microorganisms at the vaginal orifice and the cervical orifice, and cervical mucosa tissues of patients cannot be damaged.
Description
Technical Field
The invention relates to a sample collection device, in particular to a vaginal microecological sample collector.
Background
Vaginitis is a common gynecological disease of women with a morbidity of about 40-50%. Common symptoms of vaginitis are mainly vaginal itching, pain, increased secretion and malodor. In addition, it increases the chances of developing urinary tract infections, cervicitis, premature labor, pelvic inflammatory disease, and aids in the patient.
With the development of sequencing technology, vaginal micro-ecological disorders have been considered as one of the pathogenesis of vaginitis. The condition for determining whether a patient has a vaginal microecological disorder is that a vaginal microecological specimen of the patient is collected and then defined by a 16S rDNA high throughput or whole genome sequencing technique. Therefore, the precondition for judging whether the patient suffers from the micro-ecological disorder is to collect a specimen truly representing the micro-ecology of the vagina.
At present, the method for clinically collecting the vaginal microecological specimen has the following defects:
the first method is as follows: soaking sterile cotton swab with physiological saline, inserting the cotton swab into the middle of vagina, rotating, taking out the cotton swab, and storing in physiological saline test tube. The method has the following defects: the swab is contaminated by microorganisms at the vaginal orifice, so that the collected specimen cannot fully represent the vaginal microecology.
The second method is as follows: the vaginal dilator is used to extend into vagina, then the secretion of cervical orifice is collected by using a sterile cotton swab, and the cotton swab is put into a physiological saline test tube for preservation. The method has the following defects: the specimens can only represent cervical micro-ecology, but not vaginal micro-ecology. However, there are studies showing that cervical microecology is different from vaginal microecology. Therefore, the vaginal dilator sampling method is not suitable for detecting the vaginal microecology of the patient.
Therefore, in order to collect the specimen truly representing the vaginal microecology, a collecting instrument which can not only avoid the microbial contamination of the vulva mouth, but also collect the mucus in the middle of the vagina needs to be developed.
Disclosure of Invention
In order to solve the problems, the invention provides the vaginal microecological specimen collector which has a simple structure and is convenient to operate, and a microbial specimen in the middle of a vagina can be accurately collected.
In order to achieve the technical purpose and the technical effect, the invention is realized by the following technical scheme: the utility model provides a little ecological sample collector of vagina, includes from outer to interior sleeve pipe, well sleeve pipe, interior sleeve pipe and the sampling rod of matching the cover in proper order, is equipped with well sleeve pipe opening in the left end of outer sleeve pipe and is convenient for well sheathed tube and stretches out, is equipped with resistance sensor in well sleeve pipe left end, right-hand member is equipped with the warning light, resistance sensor and warning light electric connection, the sampling rod includes threaded connection's main part section and sample head, and the inside cavity and the right side opening of sample head are equipped with fore-and-aft sliding port and its bottom wane stretch out the mouth intercommunication in the sample head left end, and the width of wane stretch out the mouth is less than the width of sliding port, is equipped with the spout respectively in the sliding port both sides, is equipped with the slider in the sliding port, the slider can follow the spout reciprocates, connects the sample swab through the connecting rod on the lateral surface of slider, is equipped with a vertical movable groove along the length direction extension of main part in the main part section, is equipped with a perk board in the movable groove middle part, is equipped with a perk perforation of perk of its left and right sides face, and perk, and the perk left end penetrates from the movable groove right side and passes perk and perk stretch out the mouth and stretches out mouthful and is equipped with the perk in the opening in the inside sleeve pipe position of the sleeve pipe position of opening in the corresponding position of the sleeve pipe 48, is located in the sleeve pipe opening of the position of the sleeve pipe is in the opening cm.
Further, an annular stop block is arranged on the right side annular wall of the sampling rod so as to prop against the right end face of the inner sleeve, and the sampling swab is always not contacted with the inner wall of the left end of the inner sleeve.
Further, a first marking groove, a second marking groove and a third marking groove are respectively arranged on the right end surfaces of the sampling rod, the inner sleeve and the middle sleeve, and after the collector is assembled, the first marking groove, the second marking groove and the third marking groove are aligned, and at the moment, the inner sleeve opening, the middle sleeve opening and the sampling swab are corresponding in position.
Further, an annular scale is arranged on the wall of the outer sleeve, and a limiting ring is arranged at the right end of the outer sleeve, and the outer diameter of the limiting ring is larger than the pipe diameter of the outer sleeve so as to keep the limiting ring always positioned outside the vaginal orifice.
Further, be equipped with the stopper at wane right side end, the width of stopper is greater than the width in movable groove and avoids the wane to fully stretch into the movable inslot and influence the hand operation.
Further, be equipped with the rupture that easy department of folding is convenient for the sampling head to be located easy left side part of department in sampling head right side.
The beneficial effects of the invention are as follows:
the vaginal microecological specimen collector disclosed by the invention has a simple structure, is convenient to use, and can accurately collect the microecological specimen in the middle of the vagina; the collected specimens are not polluted by microorganisms at the vaginal orifice and the cervical orifice; and will not damage the cervical mucosal tissue of the patient.
Drawings
FIG. 1 is a schematic front view of a vaginal microecological specimen collector according to the present disclosure;
FIG. 2 is a schematic front view of a sampling wand according to the present disclosure;
FIG. 3 is a schematic left-hand view of a sampling head according to the present disclosure;
fig. 4 is a schematic right view of a vaginal microecological specimen collector according to the present disclosure.
The device comprises a 1-outer sleeve, a 2-middle sleeve, a 3-inner sleeve, a 4-sampling rod, a 5-middle sleeve opening, a 6-resistance sensor, a 7-warning lamp, an 8-main body section, a 9-sampling head, a 10-sliding port, an 11-rocker extending port, a 12-sliding block, a 13-sampling swab, a 14-movable groove, a 15-rocker support plate, a 16-rocker perforation, a 17-rocker, an 18-inner sleeve opening, a 19-middle sleeve opening, a 20-annular stop block, a 21-mark groove I, a 22-mark groove II, a 23-mark groove III, a 24-annular scale, a 25-limiting block and a 26-frangible part.
Detailed Description
The preferred embodiments of the present invention will be described in detail below with reference to fig. 1-4 so that the advantages and features of the present invention can be more readily understood by those skilled in the art, thereby making clear and defining the scope of the present invention.
In order to collect a micro-ecological sample in the middle section of the vagina so as to avoid the sample from being polluted by microorganisms at the vaginal orifice and the cervical orifice, the invention discloses a micro-ecological sample collector for the vagina, which comprises an outer sleeve 1, a middle sleeve 2, an inner sleeve 3 and a sampling rod 4 which are sequentially matched from outside to inside, wherein a middle sleeve opening 5 is arranged at the left end of the outer sleeve 1 so as to facilitate the extension of the middle sleeve 2, a resistance sensor 6 is arranged at the left end of the middle sleeve 2, a warning lamp 7 is arranged at the right end of the middle sleeve 2, and the resistance sensor 6 is electrically connected with the warning lamp 7.
The sampling rod 4 comprises a main body section 8 and a sampling head 9 which are in threaded connection, the inside of the sampling head 9 is hollow and is provided with an opening at the right side, a longitudinal sliding opening 10 is arranged at the left end of the sampling head 9 and is communicated with a rocker extending opening 11 at the bottom of the sampling head, the width of the rocker extending opening 11 is smaller than that of the sliding opening 10, sliding grooves are respectively arranged at two sides of the sliding opening 10, a sliding block 12 is arranged in the sliding opening 10, the sliding block 12 can move up and down along the sliding groove 10, the outer side surface of the sliding block 12 is connected with a sampling swab 13 through a connecting rod, a longitudinal movable groove 14 is arranged in the main body section 8, the movable groove 14 extends along the length direction of the main body section 8, a tilting support plate 15 is arranged in the middle of the movable groove 14, the middle part of the seesaw support plate 15 is provided with a seesaw perforation 16 which penetrates through the left side surface and the right side surface of the seesaw support plate 15, the left end of the seesaw 17 penetrates from the right side of the movable groove 14 and sequentially passes through the seesaw perforation 16 and the seesaw extending opening 11 and then is arranged below the sliding block 12, the wall of the inner sleeve 3 is provided with an inner sleeve opening 18, the wall of the middle sleeve 2 is provided with a middle sleeve opening 19 at a position corresponding to the inner sleeve opening 18, the length of a female vagina is about 9-10 cm, in order to ensure that the outer side end of the middle sleeve 2 is always positioned outside the vaginal opening in the use process, the length of the middle sleeve 2 is set to be 12 cm, the middle sleeve opening 19 is positioned at a position 5cm away from the left end of the middle sleeve 2, and a sampling swab 13 extending from the middle sleeve opening 19 can collect a microecological sample of the middle section of the vagina after the middle sleeve 2 extends into the vagina.
An annular stop block 20 is arranged on the right side annular wall of the sampling rod 4 so as to prop against the right end face of the inner sleeve 3, and the sampling swab 13 is always not contacted with the inner wall of the left end of the inner sleeve 3.
The right end surfaces of the sampling rod 4, the inner sleeve 3 and the middle sleeve 2 are respectively provided with a first marking groove 21, a second marking groove 22 and a third marking groove 23, and after the collector is assembled, the first marking groove 21, the second marking groove 22 and the third marking groove 23 are aligned, and at the moment, the inner sleeve opening 18, the middle sleeve opening 19 and the sampling swab 13 correspond in position.
The outer sleeve 1 is provided with the annular scale 24 on the wall so that operators can clearly know the extending amount of the outer sleeve 1 from all angles, the right end of the outer sleeve 1 is provided with the limiting ring, the outer diameter of the limiting ring is larger than the pipe diameter of the outer sleeve so as to keep the limiting ring always positioned outside the vaginal orifice, the limiting ring is arranged so that the operators can conveniently hold the position of the outer sleeve 1 to stabilize the outer sleeve 1 after the outer sleeve 1 is inserted so as to carry out subsequent operations such as inserting the middle sleeve 2, and in order to facilitate the insertion and extraction of the middle sleeve 2, the right end of the middle sleeve 2 can also be provided with the annular limiting ring.
The right side end of the rocker 17 is provided with a limiting block 25, and the width of the limiting block 25 is larger than that of the movable groove 14, so that the rocker 17 is prevented from extending into the movable groove 14 completely to influence hand operation.
The right side of the sampling head 9 is provided with the easy-to-break part 26 which is convenient for the breaking of the left part of the sampling head 9 positioned at the easy-to-break part 26.
The specific operation method comprises the following steps: the patient lies on the inspection bed, the operator keeps the mark groove upwards after assembling the collector and one finger supports wane 17 makes it to be in sliding tray bottom with movable groove 14 top contact in order to guarantee that sampling swab 13 is in the sliding tray, afterwards insert outer tube 1 patient's vagina, judge the depth of insertion according to annular scale 24 on outer tube 1, stop inserting when inserting 1~1.5 cm, afterwards advance interior sleeve pipe 2 in the vagina, when resistance sensor receives the resistance signal from the cervix, about 0.8N time (the resistance value that reaches the cervical opening comes from 100 women when using the expander to carry out cervical inspection, the average value 0.8N that detects when using the expander to the cervical opening), warning light 7 scintillation, the operator knows that well sleeve pipe 2 front end has been close the cervical opening, stop the continuation of well sleeve pipe 2 at this moment, dial down wane 17, utilize lever principle make sampling swab 13 stretch out interior sleeve pipe sampling opening 18 and well sleeve pipe sampling opening 19 after contacting with the inner wall in the middle section in proper order, keep wane 17 position, the well sleeve pipe 2 three circles accomplish the sample, afterwards withdraw from the slider 17, pull down slider 12 is followed and is pulled out the tip 3 completely, the effect that the sample rod is lost down from the 3 is held down in the groove, the sample rod is pulled out from the tip 3, can be completely, can fall into the test tube 9 completely, can be fallen into the sample rod is completely and sample collector 9 is completely broken down, can be carried out from the test tube 9, sample rod is completely, sample collector's is completely can be completely broken down from the test tube 9. The sample of the vagina middle section specimen finished by the collector can not be polluted by microorganisms at the vagina opening and the cervical orifice, and the reliability of the detection result is higher.
The foregoing description is only illustrative of the present invention and is not intended to limit the scope of the invention, and all equivalent structures or equivalent processes or direct or indirect application in other related technical fields are included in the scope of the present invention.
Claims (6)
1. The vaginal microecological specimen collector is characterized by comprising an outer sleeve (1), a middle sleeve (2), an inner sleeve (3) and a sampling rod (4) which are sequentially matched with one another from outside to inside, wherein a first middle sleeve opening (5) is formed in the left end of the outer sleeve (1), a resistance sensor (6) is formed in the left end of the middle sleeve (2), a warning lamp (7) is arranged in the right end of the middle sleeve, and the resistance sensor (6) is electrically connected with the warning lamp (7); the sampling rod (4) comprises a main body section (8) and a sampling head (9) which are in threaded connection, the inside of the sampling head (9) is hollow and is provided with an opening at the right side, a longitudinal sliding opening (10) is arranged at the left end of the sampling head (9) and is communicated with a rocker extending opening (11) at the bottom of the sampling head, the width of the rocker extending opening (11) is smaller than that of the sliding opening (10), sliding grooves are respectively arranged at two sides of the sliding opening (10), a sliding block (12) is arranged in the sliding opening (10), the sliding block (12) can move up and down along the sliding grooves, a sampling swab (13) is connected on the outer side surface of the sliding block (12) through a connecting rod, a longitudinal movable groove (14) is arranged in the main body section (8), the movable groove (14) extends along the length direction of the main body section (8), the middle part of the movable groove (14) is provided with a tilting support plate (15), the middle part of the tilting support plate (15) is provided with a tilting plate perforation (16) penetrating through the left side surface and the right side surface of the tilting support plate, the left end of the tilting plate (17) penetrates from the right side of the movable groove (14) and sequentially passes through the tilting plate perforation (16) and the tilting plate stretching out opening (11) and then is arranged below the sliding block (12), the inner sleeve wall is provided with an inner sleeve opening (18), the wall of the middle sleeve (2) is provided with a second middle sleeve opening (19) corresponding to the inner sleeve opening (18), the length of the middle sleeve (2) is set to be 12 cm, the second middle sleeve opening (19) is located at a distance from the left end 5cm of the middle sleeve (2).
2. A vaginal microecological specimen collector as claimed in claim 1, wherein an annular stop block (20) is arranged on the right side annular wall of the sampling rod (4) to abut against the right end face of the inner sleeve (3), and the sampling swab (13) is always not contacted with the left end inner wall of the inner sleeve (3).
3. A vaginal microecological specimen collector as claimed in claim 2, wherein the right end surfaces of the sampling rod (4), the inner sleeve (3) and the middle sleeve (2) are respectively provided with a first marking groove (21), a second marking groove (22) and a third marking groove (23), and after the collector is assembled, the first marking groove (21), the second marking groove (22) and the third marking groove (23) are aligned, and the inner sleeve opening (18), the second middle sleeve opening (19) and the sampling swab (13) are in corresponding positions.
4. The vaginal microecological specimen collector as claimed in claim 1, wherein an annular scale (24) is arranged on the wall of the outer sleeve (1), and a limiting ring is arranged at the right end of the outer sleeve (1), and the outer diameter of the limiting ring is larger than the pipe diameter of the outer sleeve so as to keep the limiting ring always positioned outside the vaginal orifice.
5. The vaginal microecological specimen collector as set forth in claim 1, wherein a limiting block (25) is provided at the right side end of the rocker (17), and the width of the limiting block (25) is larger than that of the movable groove (14) to prevent the rocker (17) from extending into the movable groove (14) completely to affect the hand operation.
6. A vaginal microecological specimen collector as claimed in claim 1, characterized in that a frangible portion (26) is provided on the right side of the sampling head (9).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910233034.8A CN110279436B (en) | 2019-03-26 | 2019-03-26 | Vaginal microecological specimen collector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910233034.8A CN110279436B (en) | 2019-03-26 | 2019-03-26 | Vaginal microecological specimen collector |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110279436A CN110279436A (en) | 2019-09-27 |
| CN110279436B true CN110279436B (en) | 2023-12-29 |
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ID=68001217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910233034.8A Active CN110279436B (en) | 2019-03-26 | 2019-03-26 | Vaginal microecological specimen collector |
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| Country | Link |
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| CN (1) | CN110279436B (en) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2275431Y (en) * | 1996-10-11 | 1998-03-04 | 湖南医科大学附属第三医院 | Fast single-hand biopsy gun |
| US6302853B1 (en) * | 2000-02-24 | 2001-10-16 | R & G Medical And Development Corp. | Method and apparatus for sampling cervical tissue |
| CN101879079A (en) * | 2010-06-30 | 2010-11-10 | 中国人民解放军第三军医大学第一附属医院 | Biopsy needle |
| CN103690306A (en) * | 2014-01-07 | 2014-04-02 | 魏永祥 | Specimen sampling swab |
| CN107843587A (en) * | 2017-12-14 | 2018-03-27 | 徐州市永康电子科技有限公司 | A kind of Novel gynecology-department inflammation test bar |
| CN207444962U (en) * | 2017-03-23 | 2018-06-05 | 张永涛 | Gynemetrics's vaginal fluid sampling device |
| CN108283507A (en) * | 2018-01-23 | 2018-07-17 | 孙平 | A kind of vaginal fluid sampling device for gynemetrics's clinic |
| CN210019433U (en) * | 2019-03-26 | 2020-02-07 | 江南大学 | Microecological sample collector for vagina |
-
2019
- 2019-03-26 CN CN201910233034.8A patent/CN110279436B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2275431Y (en) * | 1996-10-11 | 1998-03-04 | 湖南医科大学附属第三医院 | Fast single-hand biopsy gun |
| US6302853B1 (en) * | 2000-02-24 | 2001-10-16 | R & G Medical And Development Corp. | Method and apparatus for sampling cervical tissue |
| CN101879079A (en) * | 2010-06-30 | 2010-11-10 | 中国人民解放军第三军医大学第一附属医院 | Biopsy needle |
| CN103690306A (en) * | 2014-01-07 | 2014-04-02 | 魏永祥 | Specimen sampling swab |
| CN207444962U (en) * | 2017-03-23 | 2018-06-05 | 张永涛 | Gynemetrics's vaginal fluid sampling device |
| CN107843587A (en) * | 2017-12-14 | 2018-03-27 | 徐州市永康电子科技有限公司 | A kind of Novel gynecology-department inflammation test bar |
| CN108283507A (en) * | 2018-01-23 | 2018-07-17 | 孙平 | A kind of vaginal fluid sampling device for gynemetrics's clinic |
| CN210019433U (en) * | 2019-03-26 | 2020-02-07 | 江南大学 | Microecological sample collector for vagina |
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| CN110279436A (en) | 2019-09-27 |
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