CN110269988A - Oxygen output system based on respiratory rate and target blood oxygen levels Collaborative Control - Google Patents
Oxygen output system based on respiratory rate and target blood oxygen levels Collaborative Control Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/20—Valves specially adapted to medical respiratory devices
- A61M16/201—Controlled valves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/502—User interfaces, e.g. screens or keyboards
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M2230/00—Measuring parameters of the user
- A61M2230/20—Blood composition characteristics
- A61M2230/205—Blood composition characteristics partial oxygen pressure (P-O2)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/40—Respiratory characteristics
- A61M2230/42—Rate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/50—Temperature
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Abstract
The oxygen output system based on respiratory rate and target blood oxygen levels Collaborative Control that the invention proposes a kind of, is mainly made of control module, oxygen saturation monitor module, respiratory frequen, flow-control module, flow stop valve, human-computer interaction interface, communication module and control algolithm.The beneficial effects of the present invention are: flow stop valve keeps oxygen output synchronous with patient respiratory movement holding, than the oxygen consumption that the prior art reduces about 50% according to change of respiratory rate real-time response.Meanwhile whether oxygen saturation monitor module real-time monitoring patient blood oxygen levels are stably held in target blood oxygen control range in process of oxygen therapy, and dynamic adjusts oxygen output flow, ensure that the validity and safety of oxygen therapy.
Description
Technical field
The present invention relates to the oxygen output systems based on respiratory rate and target blood oxygen levels Collaborative Control, belong to clinical use
Medical instrument.
Background technique
Medical oxygen output control equipment is the medical instrument of medical institutions' row oxygen therapy (referred to as " oxygen therapy ") Shi Bibei,
There are commonly oxygen inhalation apparatus, ventilators etc..Existing oxygen therapy equipment oxygen output control means are more mechanical and single, in oxygen therapy
When be arranged after output flow, the parameters such as oxygen time by medical staff and realize oxygen output, during which lack and patient vitals accused of
The dynamic monitoring and feedback interaction of variation, variation can not be also accused of according to patient individual difference and life and realizes intelligentized control method.
To overcome disadvantages described above, the present inventor also proposed the technical solutions such as CN108744190A, CN104826204B, though
There are significant progress, but still Shortcomings compared with prior art, is mainly manifested in the above technology and lacks and respiratory rate is moved
State monitoring and feedback interaction.Respiratory rate is an important diagnosis basis in doctor's clinic clinical diagnosis: tachypnea (refers to
Respiratory rate is more than 24 beats/min), see fever, pain, anaemia, hyperthyroidism and heart failure etc.；It breathes too slow
(referring to respiratory rate lower than 12 beats/min) sees anesthetic or sedative excess and increased intracranial pressure etc.；Respiratory rate is deep with breathing
The variation of degree, tachypnea see paralysis of respiratory muscle, serious intestinal tympanites, ascites and obesity etc. and pulmonary disease (such as pneumonia, chest
Film inflammation, pleural effusion and pneumothorax etc.).In addition, also occurring deeply and slow breathing when serious metabolic acid poisoning, being common in sugar
Sick ketoacidosis and ureic acid poisoning etc. are urinated, therefore the respiratory rate of dynamic monitoring oxygen therapy patient is of great significance.
Summary of the invention
The invention proposes the oxygen output systems based on respiratory rate and target blood oxygen levels Collaborative Control, mainly by controlling
Module, oxygen saturation monitor module, respiratory frequen, flow-control module, flow stop valve, human-computer interaction interface, communication mould
Block and control algolithm composition；
The control module be based on control circuit made of programmable logic controller (PLC) or microcomputer development, control module with
Oxygen saturation monitor module, respiratory frequen, flow-control module, flow stop valve, human-computer interaction interface, communication module use
Integrated circuit or conducting wire connection cooperate.
The oxygen saturation monitor module is mainly made of blood oxygen probe, blood oxygen computing module and conducting wire, for dynamic
Monitor blood oxygen saturation, the pulse frequency, perfusion index (PI) of patient.Certainly, probe for detecting temperature can also be embedded in oxygen saturation monitor module
Deng the multi-parameters dynamic monitoring such as realization patient pulse, blood oxygen saturation, body temperature.
The respiratory frequen is the sensing device for identifying patient expiration and aspiratory action and frequency.Respiratory rate
Sensor includes but is not limited to thermal type respiratory frequen, acoustics respiratory frequen, differential respiratory rate sensing
Device, the concrete principle and setting method of several respiratory frequens are:
(1) thermal type respiratory frequen is using the temperature difference at human body mouth and nose when respiratory movement, and perception is exhaled and inhaled
The sensor of pneumatic work and frequency.When human body respiration, when due to exhaled gas and sucking gas there is apparent temperature in nostril periphery
It is poor to spend, therefore response time faster thermistor (most reachable≤10 delicate fastly) is set to the outlet nostril in oxygen face mask
Place, the resistance value that thermistor monitoring obtains change with expiration, air-breathing generating period, are exhaled after signal enhanced processing
Inhale frequency.
(2) acoustics respiratory frequen is different with the acoustic feature of air-breathing according to exhaling, and acoustic sensor is attached
At positions such as neck, nasal cavity, thoracic cavities, the different acoustic features of the human exhaled breath and air-breathing that are obtained according to acoustic sensor pass through
Human body respiration frequency is obtained after signal enhanced processing.
(3) differential respiratory frequen: when human body is deeply breathed, the cavitys position such as thoracic cavity or abdominal cavity can be automatically according to
Pressure sensor is placed in restraining and restraining is fixed on thoracic cavity or abdominal cavity periphery, presses by breath rhythm expansion or shrinkage
Force snesor can be expanded with dynamic sensing splanchnocoel with pressure change when shrinking, pressure increases when air-breathing, and pressure subtracts when expiration
It is few, human body respiration frequency is obtained after signal enhanced processing.It is of course also possible to which directly micropressure sensor is arranged in oxygen uptake
In mask, when oxygen face mask is fixed on patient oral cavity or nasal cavity periphery, dynamic monitoring patient expiration or air-breathing in oxygen face mask
Pressure change, when patient expiration are negative pressure when being positive pressure, air-breathing, and the signal of micropressure sensor monitoring can after enhanced processing
To directly obtain human body respiration frequency.
The flow-control module is usually passed by flow control valve and flow for adjusting and metering oxygen output flow
Sensor composition.Wherein, flow control valve uses electronic flow valve, and electronic flow valve realizes stream according to the instruction that control module provides
The motorized adjustment of size is measured, the work orders such as valve opening, flow adjustment, the valve closing that control module provides are executed；Flow
Sensor is located in the pipeline of electronic flow valve downstream position, the value of dynamic monitoring oxygen flow output.Flow-control module
It can be formed using ejector pin valve and direct current generator, establish the relation table of valve opening, supply gas pressure within the control module, realize oxygen
The control and metering of gas output flow, the technical solution advantage of this flow-control module are to reduce the cost of flow sensor,
The present inventor completely describes in CN104906677A, is not repeated.It is defeated that atomization is also provided in flow-control module
Access and atomizer interface out, oxygen uptake output and atomization output of the oxygen in output channel realize one key switching, meet oxygen therapy
Multi-functional conversion with nebulae inhalation needs.
The flow stop valve is used to control the closure or unlatching of oxygen output passage.Flow stop valve is arranged in flow
It is general using the switch control for carrying out gas circuit in electronic valve access vent line in the oxygen output tube road of control module downstream position
System；The elastic hose of one section of 3-5cm, elastic hose can also be set on the oxygen output tube road of flow-control module downstream position
A solenoid valve is arranged in periphery, closes or decontrols steam hose by solenoid valve folder and carry out gas circuit control.
The human-computer interaction interface is general using liquid crystal display and various for parameter setting of the invention and operation control
Functional key is constituted.Human-computer interaction interface should at least be equipped with oxygen uptake duration set key, flow set key, the setting of target blood oxygen levels
Key etc., function key use button, encoder, the various routine techniques of touch screen.
The communication module is sent remotely to medical attendance terminal for monitoring data, monitoring-information, information warning etc..
The technical approach such as wire transmission, bluetooth, WiFi or RF generally can be used in communication module.
Control algolithm is equipped in the control module, control algolithm is core of the invention control program, control algolithm one
As be arranged in embedded software.Control algolithm establishing element mainly has target blood oxygen levels, target blood oxygen control range, breathing
Frequency, doctor's advice flow value, intervention control time, flow adjustment range, flow regulating gradient, oxygen uptake duration, in which:
The target blood oxygen levels refer to that the blood oxygen levels for it is expected to reach and stablize holding in oxygen therapy, that is, the expection of this oxygen therapy reach
At therapeutic purpose.
The target blood oxygen control range be on the basis of target blood oxygen levels, allow dynamic blood oxygen levels deviation section,
Range between the minimum value and maximum value of the expected blood oxygen saturation for controlling and keeping i.e. in oxygen therapy.
The respiratory rate refers to patient expiration in process of oxygen therapy, the actuation time of air-breathing and the frequency, including each time
The time of expiration start and ending time, each time aspiratory action start and ending；Respiratory rate is generally by " secondary/min " in terms of
Calculate unit.
The oxygen stream magnitude that medical staff sets when the doctor's advice flow value is oxygen therapy, in human-computer interaction circle when oxygen therapy
It is set in face/or upper computer software, generally with " L/min " for unit.
After the intervention control time refers to that patient's dynamic blood oxygen levels deviate target blood oxygen control range, control module is situated between
Enter to adjust the corresponding time of oxygen output flow.Intervention control the time setting value according to clinical requirement target blood oxygen levels it is steady
It fixes time as main foundation, generally with minute (min) for unit, for example clinical requirement target blood oxygen levels are stablized and kept for 98% 3 point
Control module intervention adjustment, reduces oxygen output flow after clock, then intervention control timing definition is " 3min ".
The flow adjustment range refers to control module according to patient's blood oxygen levels dynamic change, intervention adjustment oxygen output
The interval value of flow, i.e., the minimum value and maximum range of oxygen output when intervention flow adjusts generally are with minute (L/min)
Unit.
The flow adjustment gradient refers to the gradient for increasing or reducing flow when control module intervention control each time
Value, for example flow adjustment gradient is 0.2L/min, then every intervention adjustment is primary, oxygen output flow increases or decreases 0.2L/
min.Oxygen flow automatic adjustment range in, flow regulating gradient be usually between 0.1L/min~1L/min, it is preferred that
Flow regulating gradient is set as 0.2L/min~0.5L/min.
The oxygen uptake duration is the time of the oxygen therapy start and ending of medical staff's setting, is generally single with hour (h)
Position.Oxygen uptake duration is set in human-computer interaction interface/or upper computer software, and control module provides pass after reaching oxygen uptake duration
Oxygen output order is closed, flow control valve is closed, this oxygen therapy terminates.
The parameter of each establishing element is in control algolithm:
Target blood oxygen levels setting range is 88%~99%.Within this range, by medical staff according to patient characteristic in human-computer interaction
Autonomous interface setting, such as conventional oxygen therapy patient, target blood oxygen levels are set as 96%.
Target blood oxygen control range is determining according to " target blood oxygen levels ± 1% " or " target blood oxygen levels ± 2% ", target blood oxygen control
In range write-in control algolithm processed.After medical staff sets target blood oxygen levels, target blood oxygen control range is automatically determined.For example it presses
According to " target blood oxygen levels ± 1% " standard, target blood oxygen levels that medical staff sets in human-computer interaction interface is 96%, then control is calculated
Target blood oxygen control range is between 95%~97% in method.
Respiratory rate obtains in real time according to dynamic monitoring, i.e. the holding of real-time monitoring patient breaths, expiration movement and movement
Time.
In intervention control time write-in control algolithm, it can also be set by medical staff in human-computer interaction interface or host computer
It is fixed.Usually, factory default setting intervention, which controls time setting range, is: the increase flow intervention control time is 0.5min, drops
The intervention control time that low discharge is adjusted is 3min.If the intervention control time of factory default setting is not able to satisfy clinical need
Ask, independently set by medical staff in human-computer interaction interface or host computer, intervention control time setting range be 0.5min~
Between 15min.
Flow adjusts in gradient write-in control algolithm, factory-default 0.25L/min.If the flow tune of factory default
Whole gradient is not able to satisfy clinical demand, is independently set by medical staff in human-computer interaction interface or host computer, flow regulating gradient
Setting range is between 0.1L/min~1L/min.
Doctor's advice flow value is independently set according to patient's degree of oxygen deficiency in human-computer interaction interface by medical staff, doctor's advice flow value
Be divided into four adjustment sections: low discharge oxygen uptake is set between 0.5L/min~2L/min, and middle flow oxygen inspiration is in 3L/min~4L/
It is set between min, high flow capacity oxygen uptake is set between 5L/min~8L/min, and ultra high flux oxygen uptake is in 9L/min~10L/min
Between set.
Oxygen flow automatically adjusts in range write-in control algolithm, oxygen flow automatic adjustment range be control algolithm according to
Setting doctor's advice flow value determines the oxygen output minimum value and maximum value for adjusting section and providing automatically.For example, medical staff sets
Fixed doctor's advice flow value is that 2L/min(is between 0.5L/min~2L/min), control algolithm is determined as that low discharge is inhaled automatically
Oxygen；The doctor's advice flow value of medical staff's setting is 3L/min, and control algolithm is determined as middle flow oxygen inspiration automatically；Medical staff's setting
Doctor's advice flow value be 6L/min, control algolithm is determined as high flow capacity oxygen uptake automatically.Oxygen flow automatic adjustment range is specifically:
Low discharge oxygen uptake patient, it is between 0.5L/min~2L/min that oxygen flow, which automatically adjusts range,；Middle flow oxygen inspiration patient, oxygen
It is between 0.5L/min~4L/min that flow, which automatically adjusts range,；High flow capacity oxygen uptake patient oxygen flow automatically adjusts range
Between 0.5L/min~8L/min；It is 0.5L/min~10L/min that ultra high flux oxygen uptake patient oxygen flow, which automatically adjusts range,
Between.
Oxygen uptake duration is independently set according to patient's degree of oxygen deficiency in human-computer interaction interface by medical staff, usually according to hour
It is arranged for unit, for example is set as 2 hours, 6 hours or 10 hours etc..
Further, in control algolithm each establishing element design parameter Preferable scheme is that: target blood oxygen levels set model
Enclose is 90%~96%；Target blood oxygen control range is according in " target blood oxygen levels ± 2% " write-in control algolithm；The intervention control time
Setting range: increasing the intervention control time that the flow intervention control time is 0.5min, reduction flow is adjusted is 3min；Flow tune
Section gradient is 0.2L/min.
The building principle of control algolithm is: after medical staff sets target blood oxygen levels according to patient's degree of oxygen deficiency, target blood
Oxygen control range is automatically determined according to " target blood oxygen levels ± 1% " or " target blood oxygen levels ± 2% "；Medical staff sets doctor's advice flow
Value is with after oxygen uptake duration, and into oxygen therapy mode, oxygen saturation monitor module, respiratory rate monitoring modular are synchronous to carry out blood oxygen levels, pulse frequency
And the dynamic monitoring of respiratory rate, communication module synchronized upload items monitoring-information；If blood oxygen saturation, pulse frequency or breathing frequency
Rate deviates normal value, and man-machine interface provides corresponding prompt information or information warning；Flow stop valve is real-time according to respiratory rate
Response, when patient breaths act, flow stop valve enters "ON" position, guarantees that oxygen output is unobstructed；When patient expiration acts, flow
Shut-off valve enters "Off" position, and flow stop valve blocks oxygen output, thus keep oxygen output synchronous with patient respiratory movement holding,
Oxygen is normally transported to patients with respiratory tract when patient breaths, and when patient expiration blocks oxygen conveying.At the same time, oxygen saturation monitor mould
Whether block real-time monitoring patient blood oxygen levels are stably held in target blood oxygen control range, if patient's blood oxygen levels are lower than target blood
The lower limit value of oxygen control range and reach intervention control the time when, flow-control module according to regulation flow adjustment gradient increase
Oxygen output flow；After increasing a flow adjustment gradient, if patient's dynamic blood oxygen levels are still below target blood oxygen control model
The lower limit value that encloses and when reaching the intervention control time, flow-control module increases oxygen again according to defined flow adjustment gradient
Gas output flow, the maximum value until being adjusted to oxygen flow automatic adjustment range；If oxygen output flow reaches oxygen stream
When the maximum value of amount automatic adjustment range, patient's blood oxygen levels are still below the lower limit value of target blood oxygen control range, and man-machine interface is given
The warning note that blood oxygen levels deviate out., whereas if patient's dynamic blood oxygen levels are higher than the upper limit value, simultaneously of target blood oxygen control range
When reaching the intervention control time, flow-control module reduces oxygen output flow according to the flow adjustment gradient of regulation, reduces by one
After a flow adjustment gradient, if patient's dynamic blood oxygen levels are still higher than the upper limit value of target blood oxygen control range and reach intervention
When controlling the time, flow-control module reduces oxygen output flow again according to defined flow adjustment gradient, until being adjusted to
The minimum value of oxygen flow automatic adjustment range；If oxygen output flow reaches the minimum value of oxygen flow automatic adjustment range
When, patient's blood oxygen levels are still higher than target blood oxygen control range, and man-machine interface provides the suggestiveness information for stopping oxygen uptake.Reach setting
Oxygen time it is long after, flow-control module closes oxygen output, and provides the prompt information that oxygen uptake terminates in man-machine interface.
Control algolithm has learning functionality to patient respiratory frequency, in dynamic monitoring patient respiratory frequency procedure, record
Patient breaths, retention time expiration movement and acted, control algolithm changes according to the patient respiratory frequency carries out deep learning,
And the respiratory rate rule flow stop valve for forming the patient is actively responded according to respiratory rate rule, makes flow-control module
Oxygen output is actively synchronous with patient respiratory movement；Meanwhile flow stop valve according to respiratory rate rule active control export when,
The respiratory rate of the respiratory frequen still dynamic monitoring patient, if the respiratory rate rule of the patient changes, stream
Amount shut-off valve is switched back into according to respiratory rate real-time response mode, and is started new study, formed new respiratory rate rule, such as
This is repeatedly.
The oxygen output system that the present invention is applicable in includes but is not limited to intelligent oxygen inhalation apparatus, ventilator, empty oxygen mixing
Machine oxygen-absorption atomizing double-duty plant.
The beneficial effects of the present invention are: flow stop valve makes oxygen output and suffers from according to change of respiratory rate real-time response
Person's respiratory movement keeps synchronizing, than the oxygen consumption that the prior art reduces about 50%.Meanwhile it can be according to patient's degree of oxygen deficiency
Reasonable target blood oxygen levels are set, whether oxygen saturation monitor module real-time monitoring patient blood oxygen levels are stably held in mesh in process of oxygen therapy
It marks in blood oxygen control range, and dynamic adjusts oxygen output flow, ensure that the validity and safety of oxygen therapy.
Detailed description of the invention
Fig. 1 is working principle block diagram of the present invention.
Specific embodiment
The present invention is illustrated with reference to the accompanying drawings and examples.
Embodiment 1: preparation of the invention
The main component that the present invention uses are as follows: the single-chip microcontroller that control module uses, model STC89C52, STC Corporation's production；Blood oxygen
Probe uses double-colored LED P DFE833, and issuing wavelength is 660nm and 940nm respectively；Respiratory frequen is adopted
With differential pressure pick-up, Freescale differential pressure pressure sensor MPXV3003, range ± 3kPa are specifically used；Flow control mould
Block is made of flow sensor and the combination of electronic flow proportioning valve, and the range of flow sensor is 0-10L, precision 0.1L, meter
It measures error and is no more than 2.5 grades, electronic flow proportioning valve maximum opening output flow 15L/min；Flow stop valve is using miniature normal
Enclosed solenoid valve, supply voltage 3.6V, operating pressure 0.8MPa, most short excitation time 0.05 second；Communication module uses WiFi mould
Block, model QCA9377, Qualcomm's production；Memory module uses Samsung HY27US08561A (64M)；Power supply uses
5V, 1A Medical power adapter；Charging human-computer interaction interface is pressed using 5 cun of liquid crystal displays and three encoders and a power supply
Key composition；Shell uses nontoxic PP material injection.
After each unit check is qualified, according to Fig. 1 prepared by working principle diagram, applying electronic product universal production process
PCB produces circuit board using the processes routine techniques such as patch, welding, assembling, and assembling flow-control module, flow stop valve are each
Component installs shell and control button, burn-in test after instrument is self-contained additional.
Embedded software is produced according to embedded software developing process and the building principle of inventive control algorithm, software is answered
Meet the realization of the functions such as respiratory rate and the output of target blood oxygen levels Collaborative Control oxygen.
The embedded software that production is completed is burnt in the product of self-contained completion, tests full performance, qualification passes through.
Embodiment 2: target blood oxygen levels method is set in human-computer interaction interface
When using oxygen therapy of the present invention, according to conditions of patients feature, the function key of human-computer interaction interface is operated, it is suitable that different patients are set
The target blood oxygen levels of conjunction, specifically:
(1) the target blood oxygen levels of anesthesia recovery patient are set as 96%, and target blood oxygen control range control algolithm is according to " target blood
Oxygen value ± 2% " provides automatically, i.e., the target blood oxygen control range of the patient is between 94%~98%；
(2) the target blood oxygen levels of newborn's routine oxygen uptake patient are set as 93%, target blood oxygen control range control algolithm according to
" target blood oxygen levels ± 2% " provides automatically, i.e., the target blood oxygen control range of the patient is between 90%~95%；
(3) the target blood oxygen levels of Patients with ARDS are set as 92%, and target blood oxygen control range control algolithm is pressed
It is provided automatically according to " target blood oxygen levels ± 2% ", i.e., the target blood oxygen control range of the patient is between 90%~94%；
(4) be set as 90% with the target blood oxygen levels of hypercapnia risk person, target blood oxygen control range control algolithm according to
" target blood oxygen levels ± 2% " provides automatically, i.e., the target blood oxygen control range of the patient is between 88%~92%；
(5) the target blood oxygen levels of conventional oxygen uptake patient are set as 96%, and target blood oxygen control range control algolithm is according to " target blood
Oxygen value ± 2% " provides automatically, i.e., the target blood oxygen control range of the patient is between 94%~98%.
Clinical application citing of the present invention
With the further explanation of conventional oxygen uptake patient applicating example: the target blood oxygen levels of the patient are set in 96%, and oxygen time 4 is small
When, doctor's advice flow 3Lmin.
Target blood oxygen levels are set as after 96%, target blood oxygen control range is automatically locked between 94%~98%；Set doctor's advice
After flow 3Lmin, oxygen flow automatic adjustment range is automatically set between 1~4L/min；Enter oxygen therapy mould after the completion of setting
Formula.
The movement of respiratory frequen real-time monitoring patient respiratory, flow stop valve are rung in real time according to change of respiratory rate
It answers, oxygen is normally transported to patients with respiratory tract when patient breaths, and when patient expiration stops oxygen conveying.
Oxygen saturation monitor module dynamic monitoring patient's blood oxygen saturation, when patient's blood oxygen saturation be stably held in 98% and when
When length is more than 3min, control module, which provides, reduces the instruction of oxygen output flow, and flow-control module automatically turns down oxygen output,
Turning down gradient every time is 0.25L/min；After reducing oxygen output flow, when patient's blood oxygen saturation is still stably held in 98%,
Continued to turn down a gradient at interval of 3 minutes, until the minimum value of oxygen flow automatic adjustment range；If patient's blood oxygen is saturated
When degree drops to the minimum value 94% of target blood oxygen control range, control module, which provides, in 0.5min increases oxygen output flow
Instruction, flow-control module tune up oxygen output automatically, and it is 0.25L/min that gradient is turned up every time, and every 0.5min is turned up one
Gradient, until the maximum value of oxygen flow automatic adjustment range.When by adjusting oxygen output size, but the target blood of patient
Oxygen control range still occurs to deviate and when target blood oxygen control range more than 94%~98%, and control module provides information warning,
Information warning is prompted in information warning in human-computer interaction interface or remote transmission is to nursing terminal, prompts medical staff to carry out artificial
Intervene.After the oxygen uptake duration (4 hours) for reaching setting.Oxygen output is automatically closed in flow-control module, and human-computer interaction interface mentions
Show that this oxygen therapy terminates.
Above-mentioned accompanying drawings and embodiments are only used to illustrate the technical scheme of the present invention and not to limit it.Although referring to preferred embodiment
Describe the invention in detail, those skilled in the art should understand that, can to technical solution of the present invention into
Row modification or equivalent replacement should all cover without departing from the objective and range of technical solution of the present invention in power of the invention
In sharp claimed range, protection scope of the present invention is not limited in any way.
Claims (9)
1. the oxygen output system based on respiratory rate and target blood oxygen levels Collaborative Control, mainly by control module, oxygen saturation monitor
Module, respiratory frequen, flow-control module, flow stop valve, human-computer interaction interface, communication module and control algolithm
Composition, control module and oxygen saturation monitor module, respiratory frequen, flow-control module, flow stop valve, human-computer interaction circle
Face, communication module use integrated circuit or conducting wire connection, cooperate；Control algolithm establishing element mainly has target blood oxygen
Value, target blood oxygen control range, respiratory rate, doctor's advice flow value, intervention control time, flow adjustment range, flow adjust ladder
Degree, oxygen uptake duration；The building principle of control algolithm is: after medical staff sets target blood oxygen levels according to patient's degree of oxygen deficiency, mesh
Mark blood oxygen control range is automatically determined according to " target blood oxygen levels ± 1% " or " target blood oxygen levels ± 2% "；Medical staff sets doctor's advice
After flow value and oxygen uptake duration, into oxygen therapy mode, the synchronous progress blood oxygen levels of oxygen saturation monitor module, respiratory rate monitoring modular,
The dynamic monitoring of pulse frequency and respiratory rate, communication module synchronized upload items monitoring-information；If blood oxygen saturation, pulse frequency are exhaled
Frequency departure normal value is inhaled, man-machine interface provides corresponding prompt information or information warning；Flow stop valve is according to respiratory rate
Real-time response, when patient breaths act, flow stop valve enters "ON" position, guarantees that oxygen output is unobstructed；When patient expiration acts,
Flow stop valve enters "Off" position, and flow stop valve blocks oxygen output, so that oxygen output be made to keep with patient respiratory movement
Synchronous, oxygen is normally transported to patients with respiratory tract when patient breaths, and when patient expiration blocks oxygen conveying；At the same time, blood oxygen
Whether monitoring modular real-time monitoring patient blood oxygen levels are stably held in target blood oxygen control range, if patient's blood oxygen levels are lower than
The lower limit value of target blood oxygen control range and reach intervention control the time when, flow-control module according to regulation flow adjust
Gradient increases oxygen output flow；After increasing a flow adjustment gradient, if patient's dynamic blood oxygen levels are still below target blood oxygen
The lower limit value of control range and reach intervention control the time when, flow-control module again according to defined flow adjust gradient
Increase oxygen output flow, the maximum value until being adjusted to oxygen flow automatic adjustment range；If oxygen output flow reaches
After oxygen flow automatically adjusts the maximum value of range, patient's blood oxygen levels are still below the lower limit value of target blood oxygen control range, man-machine
Interface provides the warning note of blood oxygen levels deviation；, whereas if patient's dynamic blood oxygen levels are higher than the upper of target blood oxygen control range
Limit value and reach intervention control the time when, flow-control module according to regulation flow adjustment gradient reduce oxygen output flow,
After reducing a flow adjustment gradient, if patient's dynamic blood oxygen levels are still higher than the upper limit value of target blood oxygen control range and reach
When controlling the time to intervention, flow-control module reduces oxygen output flow again according to defined flow adjustment gradient, until
It is adjusted to the minimum value of oxygen flow automatic adjustment range；If oxygen output flow reaches oxygen flow automatic adjustment range
After minimum value, patient's blood oxygen levels are still higher than the upper limit value of target blood oxygen control range, and man-machine interface provides the suggestion for stopping oxygen uptake
Property information；After the oxygen time length for reaching setting, flow-control module closes oxygen output, and provides oxygen uptake knot in man-machine interface
The prompt information of beam.
2. the oxygen output system according to claim 1 based on respiratory rate and target blood oxygen levels Collaborative Control, special
Sign also resides in: control algolithm has learning functionality to patient respiratory frequency, in dynamic monitoring patient respiratory frequency procedure, record
Patient breaths, retention time expiration movement and acted, control algolithm changes according to the patient respiratory frequency carries out deep learning,
And the respiratory rate rule of the patient is formed, flow stop valve is actively responded according to respiratory rate rule, makes flow-control module
Oxygen output actively it is synchronous with patient respiratory movement；Meanwhile flow stop valve is exported according to respiratory rate rule active control
When, the respiratory rate of the respiratory frequen still dynamic monitoring patient, if the respiratory rate rule of the patient changes,
Flow stop valve is switched back into according to respiratory rate real-time response mode, and is started new study, formed new respiratory rate rule,
Repeatedly.
3. the oxygen output system according to claim 1 based on respiratory rate and target blood oxygen levels Collaborative Control, special
Sign also resides in: the respiratory frequen is the sensing device for identifying patient expiration and aspiratory action and frequency, breathing frequency
Rate sensor includes but is not limited to thermal type respiratory frequen, acoustics respiratory frequen, differential respiratory rate biography
Sensor.
4. the oxygen output system according to claim 1 based on respiratory rate and target blood oxygen levels Collaborative Control, special
Sign also resides in: the flow stop valve is used to control the closure or unlatching of oxygen output passage, and flow stop valve setting is being flowed
In the oxygen output tube road for measuring control module downstream position.
5. the oxygen output system according to claim 1 based on respiratory rate and target blood oxygen levels Collaborative Control, special
Sign also resides in: target blood oxygen control range is determining according to " target blood oxygen levels ± 1% " or " target blood oxygen levels ± 2% ", target blood oxygen
Control range is written in control algolithm.
6. the oxygen output system according to claim 1 based on respiratory rate and target blood oxygen levels Collaborative Control, special
Sign also resides in: oxygen flow automatically adjusts in range write-in control algolithm, and it is control algolithm root that oxygen flow, which automatically adjusts range,
Determine the oxygen output minimum value and maximum value for adjusting section and providing automatically according to setting doctor's advice flow value.
7. the oxygen output system according to claim 1 based on respiratory rate and target blood oxygen levels Collaborative Control, special
Sign also resides in: the parameter of each establishing element is in control algolithm, and target blood oxygen levels setting range is 88%~99%；Target blood oxygen control
Range processed is determined according to " target blood oxygen levels ± 1% " or " target blood oxygen levels ± 2% "；Respiratory rate obtains in real time according to dynamic monitoring
It takes；Intervention control time setting range is between 0.5min~15min；Flow regulating gradient setting range be 0.1L/min~
Between 1L/min；Doctor's advice flow value is independently set according to patient's degree of oxygen deficiency in human-computer interaction interface by medical staff；Oxygen stream
Amount automatic adjustment range be specifically: low discharge oxygen uptake patient, oxygen flow automatic adjustment range be 0.5L/min~2L/min it
Between；Middle flow oxygen inspiration patient, it is between 0.5L/min~4L/min that oxygen flow, which automatically adjusts range,；High flow capacity oxygen uptake patient's oxygen
It is between 0.5L/min~8L/min that throughput, which automatically adjusts range,；Ultra high flux oxygen uptake patient oxygen flow automatically adjusts range
It is between 0.5L/min~10L/min；Oxygen uptake duration is autonomous in human-computer interaction interface according to patient's degree of oxygen deficiency by medical staff
Setting.
8. the oxygen output system according to claim 1 based on respiratory rate and target blood oxygen levels Collaborative Control, special
Sign also resides in: in control algolithm each establishing element design parameter Preferable scheme is that, target blood oxygen levels setting range is 90%~
96%；Target blood oxygen control range is according in " target blood oxygen levels ± 2% " write-in control algolithm；Intervention control time setting range:
Increasing the intervention control time that the flow intervention control time is 0.5min, reduction flow is adjusted is 3min；Flow regulating gradient is
0.2L/min。
9. the oxygen output system according to claim 1 based on respiratory rate and target blood oxygen levels Collaborative Control, special
Sign also resides in: the oxygen output system that the present invention is applicable in includes but is not limited to intelligent oxygen inhalation apparatus, ventilator, empty oxygen mixing
Machine, oxygen-absorption atomizing double-duty plant.
Priority Applications (3)
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| CN201910715675.7A CN110269988A (en) | 2019-08-05 | 2019-08-05 | Oxygen output system based on respiratory rate and target blood oxygen levels Collaborative Control |
| PCT/CN2020/070907 WO2021022785A1 (en) | 2019-08-05 | 2020-01-08 | Multifunctional oxygen output system based on cooperative control of respiratory rate and target blood oxygen value |
| CN202010445902.1A CN111481779A (en) | 2019-08-05 | 2020-05-25 | Multifunctional oxygen output system based on cooperative control of respiratory frequency and target blood oxygen value |
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| CN201910715675.7A CN110269988A (en) | 2019-08-05 | 2019-08-05 | Oxygen output system based on respiratory rate and target blood oxygen levels Collaborative Control |
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Application publication date: 20190924 |