CN110269675A - Minimally invasive cryoprobe based on phase transformation piezocaloric effect - Google Patents
Minimally invasive cryoprobe based on phase transformation piezocaloric effect Download PDFInfo
- Publication number
- CN110269675A CN110269675A CN201910569626.7A CN201910569626A CN110269675A CN 110269675 A CN110269675 A CN 110269675A CN 201910569626 A CN201910569626 A CN 201910569626A CN 110269675 A CN110269675 A CN 110269675A
- Authority
- CN
- China
- Prior art keywords
- oil
- knife
- pressure
- cutter head
- pipe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
Abstract
Title of the invention is the minimally invasive cryoprobe based on phase transformation piezocaloric effect, belongs to medical instruments field.Pressure oil 1, fuel delivery valve 2, knife bar 3 in knife, (knife bar is metal tube made of stainless steel or titanium alloy or titanium magnesium alloy, either grapheme tube, graphene oxide pipe, carbon nanotube, pipe outside diameter 1mm~10mm, thickness of pipe wall 0.1mm~2mm), oil guide pipe 4, high-voltage oil cavity 5, high pressure oil 6, piston 7, joining beam 8, jack 9 and cutter head pressure hot material 10 form.When jack 9 is pressed by piston 7 to high-voltage oil cavity 5, oil pressure is transmitted to pressure oil 1 in knife to pressurize to cutter head pressure hot material 10 through oil guide pipe 4, cutter head pressure 10 lattice of hot material is promoted to change and exotherm, and hot material lattice reinstatement absorbing and cooling temperature is pressed when pressure oil 1 is depressured in knife, achieve the effect that human canceration is organized to cure cancer due to heating, freezing repeatedly.
Description
Technical field:
The invention belongs to medical instruments fields, and in particular to a kind of minimally invasive cryoprobe based on phase transformation piezocaloric effect.
Background technique:
The minimally invasive cryoprobe applied now is argon helium knife, is Cooling and Heat Source with the argon gas of high pressure and helium, need to freeze body disease
When place, high pressure helium pneumatic transmission to cutter head swell refrigeration needs that high pressure argon gas is sent to cutter head expansion generation high temperature when rewarming.Argon helium knife
Though being widely used in medical profession, because its cost is high, usage charges are expensive, thus it is difficult to promote；The liquid nitrogen cryosurgical system proposed later solves
Problem at high cost, but because knife bar too it is cold be easy to injure normal tissue be also difficult to apply.
Refrigeration Technique based on phase transformation piezocaloric effect is to drive pressure hot material phase transformation by pressure field and generate refrigeration effect
The solid-state Refrigeration Technique answered is recognized as most potential New Refrigerating technology by U.S. Department of Energy.In the art, to pressure heat
Material applies pressure, and pressure hot material is changed into martensite by austenite under pressure, and entropy reduces and external heat release；Removal
When pressure, reverse phase transformation causes entropy to increase, and absorbs heat from the external world, generates refrigeration effect, which is referred to as piezocaloric effect.Pressure heat
The thermodynamic process of effect refrigeration is reversible, and theoretically its thermodynamic efficiency can reach inverse Carnot's cycle efficiency, energy in practice
The efficiency of realization can reach the 70%~80% of inverse Carnot's cycle efficiency, even higher.
Summary of the invention:
Aiming at the above shortcomings existing in the prior art, the present invention is freezed using piezocaloric effect, by pressure oil 1 in knife, defeated
(knife bar is metal tube made of stainless steel or titanium alloy or titanium magnesium alloy or grapheme tube, oxidation stone for oil valve 2, knife bar 3
Black alkene pipe, carbon nanotube, pipe outside diameter 1mm~10mm, thickness of pipe wall 0.1mm~2mm), oil guide pipe 4, high-voltage oil cavity 5, high pressure oil 6,
Piston 7, joining beam 8, jack 9 and cutter head pressure hot material 10 form.The lower end of knife bar 3 is made pointed cutter head, and cutter head presses hot material
10 are mounted on the interior lower end of knife bar 3, and 10 top of cutter head pressure hot material is communicated with pressure oil 1 in knife, and pressure oil 1 is to charge in knife
It is consolidated on 3 top of knife bar, and through oil guide pipe 4, fuel delivery valve 2 and 5 connection of high-voltage oil cavity.High pressure oil 6 charge 7 top of piston and with
The outlet of the entrance connection of oil guide pipe 4, oil guide pipe 4 is consolidated through fuel delivery valve 2 and 3 upper inlet connection of knife bar.
Compared with prior art, the invention has the following beneficial effects:
Minimally invasive cryoprobe provided by the invention based on phase transformation piezocaloric effect, may be implemented first to the cold of cancerous issue
Heat alternately torments, kill cancer cell, and simpler than argon helium cryoprobe in structure, cost is less expensive；Secondly, avoiding the knife of liquid nitrogen cryosurgical system
The too low problem of bar temperature, will not injure the normal skin of patient.Third, cryoprobe diameter of the invention is than argon helium cryoprobe and liquid nitrogen
The diameter of cryoprobe is small, can be as small as 1mm, is more suitable for treating the tumour of minor diameter and injuring normal cell less.
Detailed description of the invention:
Fig. 1 is the minimally invasive cryoprobe system diagram of piezocaloric effect.
Wherein: pressure oil, 2- fuel delivery valve, 3- knife bar, 4- oil guide pipe, 5- high-voltage oil cavity, 6- high pressure oil, 7- are living in 1- knife
Plug, 8- joining beam, 9- jack, 10- cutter head press hot material.
Specific embodiment:
Fig. 1 is also the minimally invasive cryoprobe system diagram of 2mm piezocaloric effect.
When operating to cancer patient, the cutter head on 3 top of knife bar is inserted into carninomatosis position, passes through joining beam 8 with jack 9
It gives piston 7 plus-pressure, high-voltage oil cavity 5 is made to boost to 125MPa, high pressure oil 6 also has 125MPa pressure and by oil guide pipe 4, fuel delivery valve
2 reach in knife bar 3, and pressure oil 1 in knife is made to boost to 125MPa, and cutter head pressure hot material 10 is made to undergo phase transition lattice deformability.Cutter head
Pressure hot material 10 is warming up to 48 DEG C after being pressurized, carninomatosis cell is also heated and heats up and be damaged, and then moves down jack 9 and high pressure oil
6 are depressurized to 0.12MPa rapidly, at this time cutter head pressure hot material 10 reinstatement and absorbing and cooling temperature to subzero 40 DEG C, carninomatosis position
It will be cooled and freeze.4~10 times repeatedly, cancer cell will be killed all, to realize minimally invasive for cancer.
Claims (1)
1. a kind of minimally invasive cryoprobe based on phase transformation piezocaloric effect, which is characterized in that the minimally invasive cryoprobe is by pressure oil in knife
(1), (knife bar is metal tube or graphene made of stainless steel or titanium alloy or titanium magnesium alloy for fuel delivery valve (2), knife bar (3)
Pipe, graphene oxide pipe, carbon nanotube, pipe outside diameter 1mm~10mm, thickness of pipe wall 0.1mm~2mm), oil guide pipe (4), high-voltage oil cavity
(5), high pressure oil (6), piston (7), joining beam (8), jack (9) and cutter head pressure hot material (10) composition；Make the lower end of knife bar (3)
At pointed cutter head, cutter head pressure hot material (10) is mounted on knife bar (3) interior lower end, and cutter head presses hot material (10) top and pressure in knife
Oily (1) communicates and pressure oil (1) is charged on knife bar (3) top and through oil guide pipe (4) fuel delivery valve (2) and high-voltage oil cavity in knife
(5) connection consolidates；High pressure oil (6) charges the entrance connection on piston (7) top and with oil guide pipe (4), the outlet of oil guide pipe (4)
It is consolidated through fuel delivery valve (2) and knife bar (3) upper inlet connection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910569626.7A CN110269675A (en) | 2019-06-27 | 2019-06-27 | Minimally invasive cryoprobe based on phase transformation piezocaloric effect |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910569626.7A CN110269675A (en) | 2019-06-27 | 2019-06-27 | Minimally invasive cryoprobe based on phase transformation piezocaloric effect |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110269675A true CN110269675A (en) | 2019-09-24 |
Family
ID=67963561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910569626.7A Pending CN110269675A (en) | 2019-06-27 | 2019-06-27 | Minimally invasive cryoprobe based on phase transformation piezocaloric effect |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110269675A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5833685A (en) * | 1994-03-15 | 1998-11-10 | Tortal; Proserfina R. | Cryosurgical technique and devices |
| US20030032950A1 (en) * | 1996-12-02 | 2003-02-13 | Altshuler Gregory B. | Cooling system for a photo cosmetic device |
| CN202637046U (en) * | 2012-05-28 | 2013-01-02 | 内蒙古民族大学 | Freezing detacher for wart |
| CN105748144A (en) * | 2016-03-07 | 2016-07-13 | 童师颖 | Liquid medium minimally invasive cold knife system |
| CN109804036A (en) * | 2016-10-14 | 2019-05-24 | 剑桥企业有限公司 | It presses the purposes of hot material and presses hot equipment |
-
2019
- 2019-06-27 CN CN201910569626.7A patent/CN110269675A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5833685A (en) * | 1994-03-15 | 1998-11-10 | Tortal; Proserfina R. | Cryosurgical technique and devices |
| US20030032950A1 (en) * | 1996-12-02 | 2003-02-13 | Altshuler Gregory B. | Cooling system for a photo cosmetic device |
| CN202637046U (en) * | 2012-05-28 | 2013-01-02 | 内蒙古民族大学 | Freezing detacher for wart |
| CN105748144A (en) * | 2016-03-07 | 2016-07-13 | 童师颖 | Liquid medium minimally invasive cold knife system |
| CN109804036A (en) * | 2016-10-14 | 2019-05-24 | 剑桥企业有限公司 | It presses the purposes of hot material and presses hot equipment |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20220205589A1 (en) | Pressurized sub-cooled cryogenic system and method of use | |
| CN1927130A (en) | Filling type beaming controllable explorer | |
| US20130331829A1 (en) | Cryoablation apparatus with enhanced heat exchange area and related method | |
| WO2009131978A3 (en) | Method and system for cryoablation treatment | |
| CN212879546U (en) | Single working medium combined type ablation operation system | |
| BR0315052A (en) | Method and system for cryogenic fibroadenoma ablation | |
| CN107049467B (en) | Adjustable cryoablation catheter | |
| CN107928864A (en) | A kind of low temperature cold therapy system | |
| CN105581838B (en) | A kind of novel tumor cryoablation conduit | |
| CN101292897A (en) | Cold-hot probe therapy system | |
| CN105902310B (en) | Cryosurgery device for adjusting air pressure to realize freezing and rewarming | |
| CN110269675A (en) | Minimally invasive cryoprobe based on phase transformation piezocaloric effect | |
| CN108514445B (en) | A freezing rifle for pricking formula cryotherapy | |
| CN102949235A (en) | Probe for tumor cold-hot hybrid treatment | |
| CN2603663Y (en) | Liquid air cryotherapy machine | |
| JPWO2013160981A1 (en) | Probe outer tube and therapeutic unit for cryosurgical device | |
| US20110015623A1 (en) | Cryotherapy device and probe for cryotherapy | |
| CN203059894U (en) | Cold and hot probe device for curing tumors | |
| CN103006316B (en) | A kind of cold and hot cutter | |
| CN205127017U (en) | Weight pressurization injection gun of shaping and beauty branch of academic or vocational study usefulness | |
| Cai et al. | Design of a new probe for tumor treatment in the alternate thermal system based on numerical simulation | |
| US8298220B2 (en) | Cryoprobe with coaxial chambers | |
| CN206995328U (en) | A kind of minimally invasive cryoprobe system of high pressure gas expansion refrigeration | |
| CN105748144A (en) | Liquid medium minimally invasive cold knife system | |
| CN209360881U (en) | Equipment and its SURGICAL NEEDLE THREADING DEVICE group for minimally invasive combination therapy |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20190924 |