CN110236694A - 基于光谱响应特性的同屏近红外双谱荧光成像方法及系统 - Google Patents
基于光谱响应特性的同屏近红外双谱荧光成像方法及系统 Download PDFInfo
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- CN110236694A CN110236694A CN201910482443.1A CN201910482443A CN110236694A CN 110236694 A CN110236694 A CN 110236694A CN 201910482443 A CN201910482443 A CN 201910482443A CN 110236694 A CN110236694 A CN 110236694A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/36—Image-producing devices or illumination devices not otherwise provided for
- A61B90/37—Surgical systems with images on a monitor during operation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B2034/2046—Tracking techniques
- A61B2034/2055—Optical tracking systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/36—Image-producing devices or illumination devices not otherwise provided for
- A61B90/37—Surgical systems with images on a monitor during operation
- A61B2090/371—Surgical systems with images on a monitor during operation with simultaneous use of two cameras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/36—Image-producing devices or illumination devices not otherwise provided for
- A61B90/37—Surgical systems with images on a monitor during operation
- A61B2090/373—Surgical systems with images on a monitor during operation using light, e.g. by using optical scanners
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111589478A (zh) * | 2020-06-05 | 2020-08-28 | 深圳市尚维高科有限公司 | 一种双通道实时荧光定量pcr仪光路系统及检测方法 |
WO2023273014A1 (zh) * | 2021-06-29 | 2023-01-05 | 南京微纳科技研究院有限公司 | 医学成像装置 |
WO2023222119A1 (zh) * | 2022-05-20 | 2023-11-23 | 深圳迈瑞生物医疗电子股份有限公司 | 多通道荧光成像系统、内窥镜成像系统和内窥镜成像方法 |
Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006340855A (ja) * | 2005-06-08 | 2006-12-21 | Olympus Medical Systems Corp | 画像処理装置 |
JP2010068924A (ja) * | 2008-09-17 | 2010-04-02 | Fujinon Corp | 画像取得方法および画像取得装置 |
CN104274156A (zh) * | 2013-07-12 | 2015-01-14 | 韩国电气研究院 | 用于检测前哨淋巴结处的nir荧光的设备和方法 |
WO2016042892A1 (ja) * | 2014-09-18 | 2016-03-24 | 株式会社島津製作所 | イメージング装置 |
CN105453542A (zh) * | 2013-08-21 | 2016-03-30 | 高通股份有限公司 | 用于通过多个图像感测元件俘获图像的系统及方法 |
CN106455979A (zh) * | 2013-12-31 | 2017-02-22 | 纪念斯隆-凯特琳癌症中心 | 用于荧光源实时多通道成像的系统、方法和设备 |
CN106572792A (zh) * | 2014-06-05 | 2017-04-19 | 海德堡大学 | 用于多光谱成像的方法和部件 |
CN106714670A (zh) * | 2014-07-24 | 2017-05-24 | 大学健康网络 | 用于诊断目的的数据的收集和分析 |
CN107003242A (zh) * | 2014-09-16 | 2017-08-01 | 劳伦斯·利弗莫尔国家安全有限责任公司 | 使用荧光剂进行染色之后在紫外激发的情况下使用荧光显微镜控制组织中的成像深度的系统和方法 |
CN107645921A (zh) * | 2015-03-16 | 2018-01-30 | 奇跃公司 | 用于诊断和治疗健康疾病的方法和系统 |
CN108430306A (zh) * | 2015-10-09 | 2018-08-21 | 瓦索普蒂奇医疗公司 | 用于使用激光散斑对比度成像快速检查脉管系统和微粒流的系统和方法 |
CN108577812A (zh) * | 2018-05-16 | 2018-09-28 | 广东欧谱曼迪科技有限公司 | 一种高精度近红外荧光导航成像系统及方法 |
US20190125229A1 (en) * | 2016-07-04 | 2019-05-02 | Hoya Corporation | Analysis device |
-
2019
- 2019-06-04 CN CN201910482443.1A patent/CN110236694B/zh not_active Ceased
Patent Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006340855A (ja) * | 2005-06-08 | 2006-12-21 | Olympus Medical Systems Corp | 画像処理装置 |
JP2010068924A (ja) * | 2008-09-17 | 2010-04-02 | Fujinon Corp | 画像取得方法および画像取得装置 |
CN104274156A (zh) * | 2013-07-12 | 2015-01-14 | 韩国电气研究院 | 用于检测前哨淋巴结处的nir荧光的设备和方法 |
CN105453542A (zh) * | 2013-08-21 | 2016-03-30 | 高通股份有限公司 | 用于通过多个图像感测元件俘获图像的系统及方法 |
CN106455979A (zh) * | 2013-12-31 | 2017-02-22 | 纪念斯隆-凯特琳癌症中心 | 用于荧光源实时多通道成像的系统、方法和设备 |
CN106572792A (zh) * | 2014-06-05 | 2017-04-19 | 海德堡大学 | 用于多光谱成像的方法和部件 |
CN106714670A (zh) * | 2014-07-24 | 2017-05-24 | 大学健康网络 | 用于诊断目的的数据的收集和分析 |
CN107003242A (zh) * | 2014-09-16 | 2017-08-01 | 劳伦斯·利弗莫尔国家安全有限责任公司 | 使用荧光剂进行染色之后在紫外激发的情况下使用荧光显微镜控制组织中的成像深度的系统和方法 |
WO2016042892A1 (ja) * | 2014-09-18 | 2016-03-24 | 株式会社島津製作所 | イメージング装置 |
CN107645921A (zh) * | 2015-03-16 | 2018-01-30 | 奇跃公司 | 用于诊断和治疗健康疾病的方法和系统 |
CN108430306A (zh) * | 2015-10-09 | 2018-08-21 | 瓦索普蒂奇医疗公司 | 用于使用激光散斑对比度成像快速检查脉管系统和微粒流的系统和方法 |
US20190125229A1 (en) * | 2016-07-04 | 2019-05-02 | Hoya Corporation | Analysis device |
CN108577812A (zh) * | 2018-05-16 | 2018-09-28 | 广东欧谱曼迪科技有限公司 | 一种高精度近红外荧光导航成像系统及方法 |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111589478A (zh) * | 2020-06-05 | 2020-08-28 | 深圳市尚维高科有限公司 | 一种双通道实时荧光定量pcr仪光路系统及检测方法 |
WO2023273014A1 (zh) * | 2021-06-29 | 2023-01-05 | 南京微纳科技研究院有限公司 | 医学成像装置 |
WO2023222119A1 (zh) * | 2022-05-20 | 2023-11-23 | 深圳迈瑞生物医疗电子股份有限公司 | 多通道荧光成像系统、内窥镜成像系统和内窥镜成像方法 |
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Address after: 528253 Room 503, Floor 5, Building A, Jingu Zhichuang Industrial Community, No. 2, Yong'an North Road, Dawu Community, Guicheng Street, Nanhai District, Foshan City, Guangdong Province (residence declaration) Patentee after: Guangdong Oupu Mandi Technology Co.,Ltd. Address before: 528251 504, block a, Jingu optoelectronics, No.1, Yong'an North Road, Nanhai District, Foshan City, Guangdong Province Patentee before: GUANGDONG OPTOMEDIC TECHNOLOGY CO.,LTD. |
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