CN110201601B - Composition formed by induction of oily components - Google Patents
Composition formed by induction of oily components Download PDFInfo
- Publication number
- CN110201601B CN110201601B CN201910481985.7A CN201910481985A CN110201601B CN 110201601 B CN110201601 B CN 110201601B CN 201910481985 A CN201910481985 A CN 201910481985A CN 110201601 B CN110201601 B CN 110201601B
- Authority
- CN
- China
- Prior art keywords
- composition
- amine oxide
- oily component
- lipophilic
- lipophilic compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Detergent Compositions (AREA)
Abstract
The invention discloses a composition formed by induction of an oily component. The composition formed by the induction of the oily component comprises the following components in percentage by mass: 1.5 to 10 percent of amine oxide surfactant, 0.2 to 15 percent of oily component and water; wherein, the aggregation form of 1.5 to 10 percent of the amine oxide surfactant aqueous solution is a micelle system; the composition induced by the oily component is a vesicular system. The invention discovers that the amine oxide surfactant can form vesicles under the induction of oily components, and does not need to be compounded by various surfactants, so that the preparation method of the composition is simple and easy to operate. The composition obtained by utilizing the amine oxide surfactant and the oily component can realize the mutual transformation of the vesicle system and the oil/water separation system by adjusting the pH value, the operation method for opening and closing the structure of the system is simple, and the amine oxide surfactant is green and environment-friendly in raw material, easy to obtain and wide in application prospect.
Description
Technical Field
The invention belongs to the technical field of daily chemical, and particularly relates to a composition formed by induction of an oily component.
Background
The surfactant can form various ordered structures such as micelles, vesicles, liquid crystals and the like through self-assembly in a solution. The control and change of the aggregation mode of the surfactant in the solution have important significance for the application of the surfactant. The vesicle is a special self-assembly structure, and is a spherical or ellipsoidal structure formed by double molecular layers formed by tail-to-tail of surfactant molecules and curled edges.
The factors determining the ordered aggregate arrangement form include molecular structure (geometric configuration, hydrophilic head group, etc.), temperature, solution environment, etc. In 1976, Israelachvili proposed the use of amphiphilic molecule geometry to describe the spatial arrangement of ordered aggregates and designed models, suggesting the concept of Critical ordered Parameters (P).
In the above formula: vcVolume of hydrophobic moiety, LcLength of hydrophobic part, A0Is the occupied area of the hydrophilic head group. The critical arrangement parameter theory simplifies the intermolecular interaction results, and explains the determinants of the molecular structures of various aggregates formed by the surfactant in the solution by using visual geometric parameters. According to the theory of Israelachvili, the critical arrangement parameter P value of the surfactant molecules for constructing the vesicle is generally between 0.5 and 1, and the P value of a micelle system is generally less than 1/3.
Structurally, the surfactant molecules of the double-tail chain conform to the characteristics of the vesicle configuration. For example, OKUMURA et al, A Study on the Adsorption of dimethyl Ammonium Chloride, disclose that dioctadecyl dimethyl Ammonium Chloride forms vesicle structures within a certain mass concentration range.
An important property of vesicles is the ability to contain multiple solutes. It can contain solutes at different sites according to their polarity. The larger hydrophilic solute is contained in its central portion. The small hydrophilic solute is contained in the region between its central portion and the polar substrate, i.e., in its respective "water chamber". The hydrophobic solute is in the hydrocarbon-based interlayer of each amphiphilic molecule bilayer. Molecules that are amphiphilic in nature, such as cholesterol, lipoproteins, and the like, can insert into the oriented bilayer to form a mixed bilayer. This entrapment is fundamental to many applications of vesicles, for example it gives vesicles the ability to carry both water-soluble and water-insoluble drugs.
Conventional commercial surfactants generally have only one chain length and are difficult to form into a vesicular structure, which limits the application of the vesicular system in industry.
Amine oxide surfactants belong to surfactants commonly used in daily chemical industry, are often used as decontamination aids, foam boosters, solubilizers and the like, are used alone or are compounded with other surfactants, and often form a micelle system.
Disclosure of Invention
The inventor finds that under the induction of an oily component, the amine oxide surfactant aqueous solution can be converted into a vesicle system by a micelle system; and can be realized by adjusting the pH of the system
And the switching is repeatedly realized at the same time.
Therefore, in order to overcome the problem that the use of the prior art vesicle system is limited, the present invention aims to provide a composition for inducing the formation of an oily component and a preparation method thereof.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
the invention provides a composition formed by induction of an oily component, which comprises the following components in percentage by mass: 1.5 to 10 percent of amine oxide surfactant, 0.2 to 15 percent of oily component and water; wherein, the amine oxide surfactant has the following characteristics: the aggregation form of 1.5-10% of the aqueous solution is a micelle system; the composition induced by the oily component is a vesicular system.
Furthermore, a micelle system is formed by 1.5-10% of an aqueous solution of the amine oxide surfactant, and after the micelle system is mixed with the oily component, a vesicle system can be formed under the induction of the oily component.
In the present invention, the meaning of "induction" is explained as follows:
according to Israelachvili's theory, the P value of amine oxide surfactant a is less than 1/3, and the surfactant is a micelle system. The inventor finds that after the oily component is added into the micelle system, the oily component is solubilized to the areas near the hydrophilic area, the palisade area, the hydrophobic area and the like of the micelle system, the transformation of the microstructure of the system is induced, and the P value is transformed from the range of less than 1/3 to the range of 1/2-1, namely the system is transformed from the micelle system to the vesicle system.
Preferably, in the composition formed by the induction of the oily component, the mass percent of the amine oxide surfactant is 2-8%; more preferably, the mass percent of the amine oxide surfactant is 2.5-6%.
Preferably, in the composition formed by the induction of the oily component, the mass percent of the oily component is 0.4-12%; further preferably, the mass percent of the oily component is 1-8%; still more preferably, the mass percentage of the oily component is 1.2% to 6%.
Preferably, in the composition induced by the oily component, the amine oxide surfactant has a general structural formula shown in formula (I):
in the formula (I), R1、R3、R4Each independently represents a substituted or unsubstituted alkyl group, alkenyl group or aryl group having carbon atoms of from C1 to C16; r2Represents a substituted or unsubstituted alkylene group having carbon atoms of C1 to C10; a. the1represents-COO-, -O-, -CONH-, -NHCO-or-OCO-, or A1Is absent; a. the2represents-COO-, -O-, -CONH-, -NHCO-or-OCO-, or A2Is absent; n is selected from 0 to 4.
Further preferably, in the amine oxide surfactant represented by the general formula (I), R is1Represents an alkyl group having carbon atoms of C6 to C16; r2Represents a carbon number of C1～C4An alkylene group of (a); r3、R4Each independently represents an alkyl group or a hydroxyalkyl group having carbon atoms of C1 to C4; a. the1represents-O-, -CONH-or-NHCO-, or A1Is absent; a. the2represents-O-, or A2Is absent; n is taken from 0, 1,2,3 or 4.
Still further preferably, in the composition in which the oily component is induced to form, the amine oxide surfactant includes at least one of octyl dimethyl amine oxide, decyl dimethyl amine oxide, dodecyl dimethyl amine oxide, tetradecyl dimethyl amine oxide, decyl amidopropyl dimethyl amine oxide, dodecyl amidopropyl dimethyl amine oxide, tetradecyl amidopropyl dimethyl amine oxide, hexadecyl amidopropyl dimethyl amine oxide, dodecyl diethoxy amine oxide, tetradecyl diethoxy amine oxide, hexadecyl diethoxy amine oxide, and C8-14 alkoxy ethyl diethoxy amine oxide.
Preferably, such oily components induce the formation of compositions in which the oily component has a ClogP > 0.
Preferably, in the composition induced by the oily component, the oily component includes at least one of hydrocarbon lipophilic compounds, alcohol lipophilic compounds, phenol lipophilic compounds, ether lipophilic compounds, ketone lipophilic compounds, aldehyde lipophilic compounds, ester lipophilic compounds, nitrogen lipophilic compounds and sulfur lipophilic compounds.
Further preferably, in such compositions, the oily component comprises styrol, p-cymene, diphenylmethane, β -myrcene, α -terpinene, β -caryophyllene, limonene, anisyl alcohol, benzyl alcohol, phenethyl alcohol, folyl alcohol, 2-hexenol, cinnamyl alcohol, 3-phenylpropanol, dimethylbenzyl methanol, myrcenol, terpineol, linalool, geraniol, menthol, citronellol, tetrahydrolinalool, α -amylcinnamyl alcohol, lauryl alcohol, maltol, dimethyl hydroquinone, eugenol, isoeugenol, thymol, carvacrol, p-chloro-m-xylenol, 3-methyl-4-isopropylphenol, anisole, p-methylanisole, isoeugenol methyl ether, diphenyl ether, vanillin, benzoil, salicylal, hydrogenated cinnamaldehyde, syringaldehyde, capric aldehyde, geranial aldehyde, cumyl alcohol, p-, At least one of undecanal, laurylaldehyde, myristyl aldehyde, acetophenone, 2-heptanone, p-methylacetophenone, 2-octanone, butyl acetate, methyl phenylacetate, benzyl acetate, phenylethyl propionate, ethyl hexanoate, ethyl laurate, benzyl butyrate, linalyl formate, isobutyl phenylacetate, ethyl heptanoate, amyl butyrate, geranyl formate, linalyl acetate, amyl valerate, ethyl octanoate, geranyl acetate, phenylethyl phenylacetate, lauryl isovalerate, p-tert-butylcyclohexyl acetate, allyl octanoate, benzyl salicylate, linalyl propionate, ethyl nonanoate, lauryl cinnamate, geranyl isovalerate, hexadecanolide, 3-methylthio, benzylmercaptan, hexyloxy acetonitrile, ethyl anthranilate, citronellyl nitrile, citral, linalyl anthranilate.
Preferably, the composition induced by the oily component further comprises an adjuvant, the adjuvant comprising a pH adjusting agent.
Preferably, the adjuvant of the composition further comprises at least one of a viscosity modifier, a preservative, a bactericide, an antioxidant, a colorant, and a whitening agent.
Preferably, in the composition, the mass percent of the auxiliary agent is 0.003-8%; more preferably, the mass percent of the auxiliary agent is 0.005-5%.
The invention also provides a preparation method of the composition formed by the induction of the oily component, and the preparation method comprises the steps of weighing the raw materials according to the components, and mixing to obtain the composition.
Preferably, the composition is prepared by weighing the raw materials according to the above composition, adding the components except water into water, and mixing to obtain the composition.
Preferably, in the preparation of such compositions, the method of mixing may be selected from stirring and/or sonication.
Preferably, in the preparation method of the composition, the temperature of water before mixing is controlled to be 15-70 ℃; further preferably, the temperature of the water is 20 ℃ to 60 ℃; still more preferably, the temperature of the water is 25 ℃ to 50 ℃.
Preferably, the composition is prepared by first adding the amine oxide surfactant to water, and mixing with stirring; adding oily component, stirring, and mixing to obtain the composition.
Preferably, the method for preparing the composition further comprises the step of adding a pH regulator to adjust the pH value of the composition after mixing, and the mutual transformation of the vesicle system and the oil/water separation system is realized by adjusting the pH value of the composition.
Further preferred, is a process for the preparation of such a composition, wherein the composition is an oil/water separation system when the pH of the composition is adjusted to < 3.5; when the pH value of the composition is adjusted to be more than or equal to 3.5, the composition is a vesicle system; still more preferably, the pH value of the composition is adjusted to 3.5-11.5, so that the composition forms a vesicle system; in a further step, the pH value is preferably 5.0-9.5, so that the composition forms a vesicle system.
The invention also provides application of the composition formed by the induction of the oily component in preparing daily chemicals.
Preferably, in application, the daily chemical product comprises but is not limited to a flavoring product, a bacteriostatic product, a bactericidal product, a disinfectant product, a cleaning product, a softening product, an antistatic product and a fabric care product; the treatment objects of the daily chemicals include, but are not limited to, human bodies, fabrics, hard surfaces, air.
Preferably, the composition induced by the oily component is made into a flavored product.
Preferably, the composition formed by inducing the oily component is mixed with a bactericide to prepare a bacteriostatic/bactericidal/disinfectant product.
The invention has the beneficial effects that:
the invention discovers that the amine oxide surfactant can form vesicles under the induction of oily components, and does not need to be compounded by various surfactants, so that the preparation method of the composition is simple and easy to operate.
The composition obtained by utilizing the amine oxide surfactant and the oily component can realize the mutual transformation of the vesicle system and the oil/water separation system by adjusting the pH value, the operation method for opening and closing the structure of the system is simple, and the amine oxide surfactant is green and environment-friendly in raw material, easy to obtain and wide in application prospect.
Drawings
FIG. 1 is a transmission electron micrograph of an aqueous amine oxide solution of comparative example 1;
FIG. 2 is a transmission electron micrograph of the composition of example 1;
FIG. 3 is a transmission electron micrograph of the composition of example 5;
FIG. 4 is a transmission electron micrograph of the composition of example 12;
FIG. 5 is a transmission electron micrograph of the composition of example 13.
Detailed Description
The invention provides a composition for inducing formation of an oily component, which comprises the following components: amine oxide surfactants, oily components and water.
The composition in which the oily component is induced to form may also include adjuvants.
The ingredients of the composition induced by this oily component are further illustrated below:
amine oxide surfactants
In the present invention, the amine oxide surfactant means a surfactant whose aqueous solution forms a micelle system.
The structural formula of the amine oxide surfactant can be seen in formula (I):
in the formula (I), R1、R3、R4Each independently represents a substituted or unsubstituted alkyl group, alkenyl group or aryl group having carbon atoms of from C1 to C16; r2Represents a substituted or unsubstituted alkylene group having carbon atoms of C1 to C10; a. the1represents-COO-, -O-, -CONH-, -NHCO-or-OCO-, or A1Is absent; a. the2represents-COO-, -O-, -CONH-, -NHCO-or-OCO-, or A2Is absent; n is selected from 0 to 4.
Further, the amine oxide surfactant includes, but is not limited to, at least one of octyl dimethyl amine oxide, decyl dimethyl amine oxide, dodecyl dimethyl amine oxide, tetradecyl dimethyl amine oxide, decyl amidopropyl dimethyl amine oxide, dodecyl amidopropyl dimethyl amine oxide, tetradecyl amidopropyl dimethyl amine oxide, hexadecyl amidopropyl dimethyl amine oxide, dodecyl diethyl amine oxide, tetradecyl diethyl amine oxide, hexadecyl diethyl amine oxide, and C8-14 alkoxy ethyl diethyl amine oxide.
The inventor of the invention has found through a great deal of experiments that the aqueous solution (with the concentration of 1.5 wt% to 10 wt%) of the amine oxide surfactant is a micelle system and can form a vesicle system under the induction of an oily component after being mixed with the oily component.
In the composition, the amine oxide surfactant is preferably 1.5 to 10 percent by mass; further preferably 2% to 8%; still more preferably from 2.5% to 6%.
Oil component
The n-octanol/water partition coefficient of an organic compound reflects the ability of a chemical substance to migrate between the aqueous phase and the organism, and is often characterized by a logP value. The logP value refers to the logarithm of the ratio of the partition coefficients of a substance in n-octanol (oil) and water. Reflecting the partitioning of the material in both the oil/water phases. The higher the logP value, the more oleophilic the substance; conversely, the smaller the size, the more hydrophilic, i.e., the better the water solubility. logP can be calculated by the following formula:
logP＝log(Co/Cw)
in the above formula, Co: the equilibrium concentration of a substance in n-octanol; cw: the equilibrium concentration of a substance in water.
The oily component of the present invention, i.e., logP > 0.
The logP value can be obtained by experimental methods, and the method mainly comprises a direct method and an indirect method. The direct method comprises a shake flask method, a two-phase titration method and an extraction method; indirect methods include column generation, chromatography. However, the experimental method is expensive and the test operation is complicated, so that a calculation method is developed. There are two main methods of calculation, one is by the fragment additivity of organic compounds and the other is by the internal relation between other physicochemical parameters of the compounds and their octanol/water partition coefficients. The logP value, namely ClogP, obtained by the calculation method can make up for the defects of the experimental method, so that a great deal of professional software is introduced, such as CLOGP software, ProLogP module of Pallas software, ClogP/CMR module of SYBYL software and the like (Suhua et al: Compound lipid-water distribution coefficient calculation software and comparative research [ J ]. Chinese university of pharmacy, 2008,39(2): 178-. The ClogP value of the oily component can be calculated using software, such as Chemdraw.
The oily component is lipophilic compound, and comprises at least one of hydrocarbon lipophilic compound, alcohol lipophilic compound, phenol lipophilic compound, ether lipophilic compound, ketone lipophilic compound, aldehyde lipophilic compound, ester lipophilic compound, nitrogen-containing lipophilic compound, and sulfur-containing lipophilic compound.
Lipophilic compounds are classified from the point of view of functional groups:
hydrocarbon lipophilic compounds: compounds containing only carbon and hydrogen elements, such as terpenes;
alcoholic lipophilic compounds: a compound containing a hydroxyl group which is not directly bonded to a benzene ring;
phenolic lipophilic compounds: compounds in which the hydroxyl group is directly bonded to the benzene ring;
lipophilic ether compounds: a compound containing an-O-bond;
ketone lipophilic compounds: a compound containing > C ═ O bonds;
aldehyde lipophilic compounds: a compound containing a — CHO functional group;
lipophilic compounds of esters: a compound containing a-COO-functional group;
nitrogen-containing lipophilic compounds: a compound containing a nitrogen element;
sulfur-containing lipophilic compounds: a compound containing elemental sulfur.
Further preferably, the hydrocarbon lipophilic compound includes but is not limited to at least one of styrax, p-cymene, diphenylmethane, beta-myrcene, alpha-terpinene, beta-caryophyllene and limonene; the alcoholic lipophilic compound includes but is not limited to at least one of anisic alcohol, benzyl alcohol, phenethyl alcohol, leaf alcohol, 2-hexenol, cinnamyl alcohol, 3-phenylpropanol, dimethyl benzyl carbinol, myrcenol, terpineol, linalool, geraniol, menthol, citronellol, tetrahydrolinalool, alpha-amyl cinnamyl alcohol and lauryl alcohol; the phenolic and ether lipophilic compounds include but are not limited to at least one of maltol, dimethyl hydroquinone, eugenol, isoeugenol, thymol, carvacrol, parachlorometaxylenol, 3-methyl-4-isopropylphenol, anisole, p-methylanisole, isoeugenol methyl ether and diphenyl ether; the aldehyde lipophilic compound comprises at least one of vanillin, benzoic aldehyde, salicylaldehyde, hydrocinnamaldehyde, syringaldehyde, caprilic aldehyde, undecylenic aldehyde, lauraldehyde and myristylic aldehyde; the ketone lipophilic compound comprises at least one of acetophenone, 2-heptanone, p-methylacetophenone and 2-octanone; lipophilic compounds of the ester type include, but are not limited to, at least one of butyl acetate, methyl phenylacetate, benzyl acetate, phenylethyl propionate, ethyl hexanoate, ethyl laurate, benzyl butyrate, linalyl formate, isobutyl phenylacetate, ethyl heptanoate, amyl butyrate, geranyl formate, linalyl acetate, amyl valerate, ethyl octanoate, geranyl acetate, phenylethyl phenylacetate, lauryl isovalerate, p-tert-butylcyclohexyl acetate, allyl octanoate, benzyl salicylate, linalyl propionate, ethyl nonanoate, lauryl cinnamate, geranyl isovalerate, hexadecanolide; the lipophilic compounds containing nitrogen and sulfur include but are not limited to at least one of 3-methylthiopropanal, benzylthiol, hexyloxy acetonitrile, ethyl anthranilate, citronellyl nitrile, citral, and linalyl anthranilate. Further, the names, structures and ClogP values of these lipophilic compounds can be respectively shown in tables 1-7. The oily component of the present invention may be selected from one or more lipophilic compounds in tables 1 to 7.
TABLE 1 lipophilic compounds of hydrocarbons
TABLE 2 lipophilic compounds of alcohols
TABLE 3 lipophilic compounds of phenols and ethers
TABLE 4 lipophilic compounds of aldehydes
TABLE 5 lipophilic compounds of ketones
TABLE 6 lipophilic compounds of esters
TABLE 7 lipophilic compounds containing nitrogen and sulfur
In the composition, the mass percent of the oily component is preferably 0.2-15%; further preferably 0.4 to 12%; still more preferably 1% to 8%; more preferably 1.2% to 6%.
Third, the auxiliary agent
The composition further comprises an auxiliary agent selected from at least one of pH regulator, viscosity regulator, antiseptic, bactericide, antioxidant, colorant, and whitening agent.
In the composition, the mass percent of the auxiliary agent is preferably 0.001-10%; further preferably 0.003 to 8 percent; still more preferably 0.005% to 5%.
3.1pH adjusting agent
The pH adjusting agent used in the present invention may be any known pH adjusting agent including inorganic and/or organic alkalinity sources and acidifying agents.
Inorganic alkalinity sources include, but are not limited to: water-soluble alkali metal hydroxides, oxides, carbonates, bicarbonates, borates, silicates, metasilicates, or mixtures thereof; water-soluble alkaline earth metal hydroxides, oxides, carbonates, bicarbonates, borates, silicates, metasilicates, or mixtures thereof; water-soluble boron group metal hydroxides, oxides, carbonates, bicarbonates, borates, silicates, metasilicates, or mixtures thereof; and mixtures thereof. Or water soluble phosphates as alkalinity sources including pyrophosphates, orthophosphates, polyphosphates, phosphonates, and mixtures thereof. Preferably, the source of inorganic alkalinity is sodium hydroxide, potassium hydroxide, and mixtures thereof; further preferably, the source of inorganic alkalinity is sodium hydroxide.
Sources of organic alkalinity include, but are not limited to: primary amines, secondary amines, tertiary amines, and mixtures thereof. Other sources of organic alkalinity are alkanolamines, or mixtures of alkanolamines. Suitable alkanolamines may be selected from the group consisting of lower alkanol monoalkanolamines, dialkanolamines and trialkanolamines, such as monoethanolamine, diethanolamine or triethanolamine. Preferably, it is selected from monoalkanolamines, dialkanolamines, and especially monoethanolamine. In certain particular embodiments, additional alkanolamines, such as triethanolamine, may be used as a buffering agent.
Inorganic acidulants include, but are not limited to: HF. HCl, HBr, HI, boric acid, phosphoric acid, phosphonic acid, sulfuric acid, sulfonic acid, and mixtures thereof.
Organic acidulants include, but are not limited to: citric acid, substituted and/or unsubstituted branched, straight chain and/or cyclic C1 to C30 carboxylic acids, and mixtures thereof.
Preferably, the pH value of the composition is 3.5-11.5; further preferably, the pH value of the composition is 5.0-9.5.
3.2 viscosity modifiers
In the invention, the viscosity can be adjusted by changing the proportion of the amine oxide surfactant and the oily component, and the viscosity can be further adjusted by adding a viscosity regulator. Preferably, the viscosity regulator is an inorganic salt regulator, and can be one or more selected from sodium chloride, ammonium chloride, magnesium chloride and calcium chloride.
If a viscosity modifier is used, the preferred mass percentage of the viscosity modifier in the composition is 0.05-2.5%.
3.3 preservatives
In the invention, the preservative is selected from one or more of cason, 2-methyl-4-isothiazolin-3-ketone, 5-chloro-2-methyl-4-isothiazolin-3-ketone, 3-iodo-2-propynyl butyl carbamate, dimethylolhydantoin and bronopol.
If a preservative is used, the preservative is preferably present in the composition in an amount of 0.001% to 0.5% by weight.
3.4 Fungicide
In the invention, the bactericide is selected from one or more of decyl/dodecyl/tetradecyl trimethyl ammonium chloride, dioctyl/didecyl/didodecyl dimethyl ammonium chloride, dodecyl dimethyl benzyl ammonium chloride, polyoxyethylene trimethyl ammonium chloride, organosilicon quaternary ammonium salt, triclosan, dichlorosheng, 1,1' -hexamethylene-bis [5- (4-aminophenyl) ] biguanide hydrochloride, polyhexamethylene biguanide hydrochloride, chlorhexidine acetate, chlorhexidine gluconate, chitosan quaternary ammonium salt, sodium benzoate, potassium sorbate and silver ion bactericide.
If a bactericide is used, the preferable mass percentage of the bactericide in the composition is 0.1-2%.
3.5 antioxidants
In the invention, the antioxidant is selected from one or more of ascorbic acid, 2, 6-di-tert-butyl-4-methylphenol (BHT), Butyl Hydroxy Anisole (BHA), tocopherol and propyl gallate.
If an antioxidant is used, the antioxidant is preferably present in the composition in an amount of 0.1% to 1% by weight.
3.6 coloring Agents
In the present invention, the colorant may be selected from pigments and/or dyes, and may include colorants commonly used in laundry detergents or fabric softeners.
If a colorant is used, the colorant is preferably present in the composition at a level of from 0.0001% to 0.5% by weight; further preferably 0.01 to 0.1% by mass.
3.7 whitening Agents
In the invention, the brightener is a fluorescent brightener and is selected from one or more of stilbene biphenyl type fluorescent brightener, triazinyl amino stilbene type fluorescent brightener, bis (1,2, 3-triazole-2-yl) stilbene type fluorescent brightener, bis (benzofuran-2-yl) biphenyl, 1, 3-diphenyl-2-pyrazoline and coumarin type fluorescent brightener; preferably, the optical brightener is a sulfonated product, in the form of its alkali metal salt, including but not limited to stilbene-based compounds such as one or more of 4, 4' -bis (2-sodium sulfonate styryl) biphenyl, bis-triazinylstilbene derivatives.
If fluorescent whitening agents are used, the fluorescent whitening agents are preferably present in the composition in an amount of 0.001% to 0.5% by weight.
The preparation method of the composition comprises the steps of weighing the raw materials according to the components, and mixing to obtain the composition.
Preferably, the composition is prepared by weighing the raw materials according to the above composition, adding the components except water to water, and mixing to obtain the composition.
Preferably, in the preparation of such compositions, the method of mixing may be selected from stirring and/or sonication.
Preferably, in the preparation method of the composition, the temperature of water before mixing is controlled to be 15-70 ℃; further preferably, the temperature of the water is 20 ℃ to 60 ℃; still more preferably, the temperature of the water is 25 ℃ to 50 ℃.
Preferably, the preparation method of the composition is specifically that the amine oxide surfactant is added into water and stirred and mixed; adding oily component, stirring, and mixing to obtain the composition.
Preferably, the method of preparing such a composition further comprises the step of adjusting the pH after mixing.
Preferably, in the preparation method of the composition, the pH value is adjusted by adding a pH regulator to adjust the pH value, and the vesicle system and the oil/water separation system are mutually converted by adjusting the pH value of the composition. When the pH of the composition is adjusted to <3.5, the composition is an oil/water separation system; when the pH value of the composition is adjusted to be more than or equal to 3.5, the composition is a vesicle system; the pH of the vesicle system composition is more preferably 3.5 to 11.5, and still more preferably 5.0 to 9.5.
In some specific embodiments, the composition is prepared by first adding the amine oxide surfactant to water, and stirring for 5-15 min to dissolve until no significant particles are present; and adding the oily component, stirring for 30-50 min, and uniformly mixing to obtain the composition.
In some specific embodiments, the composition is prepared by first adding the amine oxide surfactant to water, and stirring for 5-15 min to dissolve until no significant particles are present; adding the oily component, stirring for 30-50 min, and mixing uniformly; then adding a pH regulator to regulate the pH, stirring and cooling to obtain the composition.
The composition formed by the induction of the oily component can be used for preparing daily chemicals such as flavoring products, bacteriostatic products, bactericidal products, disinfectant products, cleaning products, softening products, antistatic products, fabric care products and the like.
The present invention will be described in further detail with reference to specific examples. The following examples are merely illustrative and explanatory of the present invention and should not be construed as limiting the scope of the invention. All the technologies realized based on the content of the present invention are covered in the protection scope of the present invention.
The raw materials and reagents used in the examples are, unless otherwise specified, commercially available from conventional sources or can be prepared by known methods.
Examples 1 to 15
C12/14 alkyldimethylamine oxides (mass ratio C)12/C147/3) the aqueous solution is a micellar system when the oily component is absent. When a certain amount of oily component is added to the aqueous solution of amine oxide forming a micelle system, the system forms a vesicle structure under the induction of the oily component.
Compositions of amine oxide surfactants which form vesicles under induction of oily components examples 1 to 14 are shown in tables 8 to 9, while an aqueous solution of C12/14 alkyldimethylamine oxide alone was used as comparative example 1 and is also shown in Table 8. The amine oxide surfactant used in tables 8-9, raw material C12/14 alkyl dimethyl amine oxide, was dodecyl dimethyl amine oxide and tetradecyl dimethyl amine oxide in a mass ratio of 7: 3, and C12 alkyldimethylamine oxide. The amount of water used can be calculated by subtracting the other non-water components of the composition from 100%.
The preparation method of the composition in the table 8-9 comprises the following steps: according to the composition in the table, the amine oxide surfactant is added into water with the temperature of 25 ℃, and stirred for 10min to be dissolved; and adding the oily component, stirring for 40min, and mixing uniformly to obtain the composition with the vesicle structure.
The amine oxide surfactant used in the examples is a commercial raw material, and the amine oxide active ingredient is 10 wt% -40 wt%. The amine oxide surfactant content reported in the table below is its substantial concentration by mass in the composition. TABLE 8 compositions and test results for examples 1-6 and comparative example 1
TABLE 9 compositions and test results for examples 7-14
The transmission electron micrograph of the aqueous amine oxide system of comparative example 1 shows FIG. 1. As can be seen from fig. 1, the system of comparative example 1 is a micelle structure. When a certain amount of lipophilic compound is added to the amine oxide aqueous solution forming the micelle system, the system can form a vesicle system under the induction of an oily component of the lipophilic compound, such as examples 1 to 14. FIG. 2 is a transmission electron micrograph of the composition of example 1. As can be seen from fig. 2, the lipophilic compound added to comparative example 1 can induce the conversion of the aqueous amine oxide solution from the micellar system to the vesicular system. The transmission electron micrographs of the compositions of example 5 and example 12 can be seen in FIG. 3 and FIG. 4, respectively. As can be seen from fig. 2 to 4, the vesicle structure is a multilamellar vesicle with 1-6 layers; the vesicle size has a certain distribution, the minimum size is about 30nm, and the maximum size can reach about 800 nm.
Example 13 parachlorometaxylenol is adopted to induce C12/14 alkyldimethylamine oxide to form a vesicle structure, and a transmission electron micrograph is shown in figure 5, wherein the vesicle structure is small in size, is about tens of nanometers in size, and mainly comprises unilamellar vesicles.
Through repeated experiments, the vesicle system composition prepared by the invention is added with a pH regulator, and the formed composition can realize
May be repeatedly cycled a plurality of times. The test conditions and results are shown in Table 10.
Table 10 a specific method for preparing this example 15 composition is: adding amine oxide surfactant into water of 25 deg.C, stirring for 10min to dissolve; adding the oily components, stirring for 40min, and mixing; then adding pH regulator, and stirring to obtain the composition. The pH regulator can be acidic pH regulator such as citric acid; or with an alkaline pH adjusting agent such as sodium hydroxide. The oily component used in table 10 is selected from the lipophilic compounds mentioned above.
TABLE 10 EXAMPLE 15 composition systems interconversion test
From the test results, the composition obtained by utilizing the amine oxide surfactant and the oily component can realize the mutual transformation of the vesicle system and the oil/water separation system by adjusting the pH value, the operation method of the switch system structure is simple, and the used amine oxide surfactant is green and environment-friendly in raw material, easy to obtain and wide in application prospect.
The invention can lead the oily component which is not dissolved in water to be evenly dispersed in water, and can prepare products of different types by adding different types of oily components, for example, adding perfume can prepare fragrance-enhanced products, thus realizing the lasting fragrance retention of human bodies, fabrics, hard surfaces and air; adding bactericide to prepare bacteriostatic/bactericidal/disinfectant products. Meanwhile, the composition disclosed by the invention has a certain cleaning effect, can realize the effects of cleaning and lasting fragrance of human bodies, fabrics and hard surfaces, and can realize a stronger cleaning effect if other surfactants or components with a decontamination effect are additionally compounded.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.
Claims (3)
1. A composition induced by an oily component, characterized in that: the composite material comprises the following components in percentage by mass: 1.5-10% of amine oxide surfactant, 0.2-15% of oily component and water; also comprises adding a pH regulator to regulate the pH value of the composition;
the amine oxide surfactant has the following characteristics: the aggregation form of 1.5% -10% of the aqueous solution is a micelle system, and after being mixed with the oily component, the micelle system can be formed under the induction of the oily component;
the amine oxide surfactant comprises at least one of octyl dimethyl amine oxide, decyl dimethyl amine oxide, dodecyl dimethyl amine oxide, tetradecyl dimethyl amine oxide, decyl amidopropyl dimethyl amine oxide, dodecyl amidopropyl dimethyl amine oxide, tetradecyl amidopropyl dimethyl amine oxide, hexadecyl amidopropyl dimethyl amine oxide, dodecyl dihydroxyethyl amine oxide, tetradecyl dihydroxyethyl amine oxide, hexadecyl dihydroxyethyl amine oxide and C8-14 alkoxy ethyl dihydroxyethyl amine oxide;
the oily component comprises at least one of hydrocarbon lipophilic compounds, alcohol lipophilic compounds, phenol lipophilic compounds, ether lipophilic compounds, ketone lipophilic compounds, aldehyde lipophilic compounds, ester lipophilic compounds, nitrogen lipophilic compounds and sulfur lipophilic compounds; the hydrocarbon lipophilic compound comprises at least one of styrax, p-cymene, diphenylmethane, beta-myrcene, alpha-terpinene, beta-caryophyllene and limonene; the alcoholic lipophilic compound comprises at least one of anisic alcohol, benzyl alcohol, phenethyl alcohol, leaf alcohol, 2-hexenol, cinnamyl alcohol, 3-phenylpropanol, dimethyl benzyl methanol, myrcenol, terpineol, linalool, geraniol, menthol, citronellol, tetrahydrolinalool, alpha-amyl cinnamyl alcohol and lauryl alcohol; the phenolic lipophilic compounds and ether lipophilic compounds comprise at least one of maltol, dimethyl hydroquinone, eugenol, isoeugenol, thymol, carvacrol, parachlorometaxylenol, 3-methyl-4-isopropylphenol, anisole, p-methylanisole, isoeugenol methyl ether and diphenyl ether; the aldehyde lipophilic compound comprises at least one of vanillin, benzoic aldehyde, salicylaldehyde, hydrocinnamaldehyde, syringaldehyde, capric aldehyde, undecylenic aldehyde, lauraldehyde and myristylal aldehyde; the ketone lipophilic compound comprises at least one of acetophenone, 2-heptanone, p-methylacetophenone and 2-octanone; the ester lipophilic compound comprises at least one of butyl acetate, methyl phenylacetate, benzyl acetate, phenethyl propionate, ethyl caproate, ethyl laurate, benzyl butyrate, linalyl formate, isobutyl phenylacetate, ethyl heptanoate, amyl butyrate, geranyl formate, linalyl acetate, amyl valerate, ethyl caprylate, geranyl acetate, phenethyl phenylacetate, lauryl isovalerate, p-tert-butylcyclohexyl acetate, allyl caprylate, benzyl salicylate, linalyl propionate, ethyl nonanoate, lauryl cinnamate, geranyl isovalerate and hexadecanolide; the nitrogen-containing lipophilic compound and the sulfur-containing lipophilic compound comprise at least one of 3-methylthiopropanal, benzylthiol, hexyloxy acetonitrile, ethyl anthranilate, citronellyl nitrile, citral and linalyl anthranilate;
the pH regulator comprises an alkalinity source of inorganic and/or organic type and an acidifying agent;
the preparation method of the composition formed by the induction of the oily components comprises the steps of weighing the raw materials according to the components, and mixing to obtain the composition; the step of adding a pH regulator to regulate the pH value of the composition after mixing is also included, and mutual transformation of the vesicle system and the oil/water separation system is realized by regulating the pH value of the composition; when the pH of the composition is less than 3.5, the composition is an oil/water separation system; when the pH value of the composition is 3.5-9.5, the composition is a vesicle system.
2. A method for preparing the composition induced by the oily component of claim 1, which is characterized in that: weighing the raw materials according to the components in the composition, and mixing to obtain the composition; the step of adding a pH regulator to regulate the pH value of the composition after mixing is also included, and mutual transformation of the vesicle system and the oil/water separation system is realized by regulating the pH value of the composition; when the pH of the composition is adjusted to <3.5, the composition is an oil/water separation system; when the pH of the composition is adjusted to be 3.5-9.5, the composition is a vesicle system.
3. Use of a composition according to claim 1 for the preparation of a commodity chemical.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910481985.7A CN110201601B (en) | 2019-06-04 | 2019-06-04 | Composition formed by induction of oily components |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910481985.7A CN110201601B (en) | 2019-06-04 | 2019-06-04 | Composition formed by induction of oily components |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110201601A CN110201601A (en) | 2019-09-06 |
| CN110201601B true CN110201601B (en) | 2021-08-03 |
Family
ID=67790713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910481985.7A Active CN110201601B (en) | 2019-06-04 | 2019-06-04 | Composition formed by induction of oily components |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110201601B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1339579A (en) * | 2001-10-10 | 2002-03-13 | 常耀辉 | Water base micro emulsion cleaning agent for heavy oil pollution and its prepn |
| US7262158B1 (en) * | 1999-07-01 | 2007-08-28 | Johnson & Johnson Companies, Inc. | Cleansing compositions comprising a liquid silicone and ester mixture |
| CN104284650A (en) * | 2012-02-10 | 2015-01-14 | 斯蒂潘公司 | Structured surfactant suspending systems |
| CN107929168A (en) * | 2017-12-28 | 2018-04-20 | 江南大学 | A kind of moisturizing betaplex gentle cleansing milk |
| CN109620747A (en) * | 2018-12-28 | 2019-04-16 | 江南大学 | A kind of preparation method of the high viscoelastic surfactant vermiculate glues with pH response |
-
2019
- 2019-06-04 CN CN201910481985.7A patent/CN110201601B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7262158B1 (en) * | 1999-07-01 | 2007-08-28 | Johnson & Johnson Companies, Inc. | Cleansing compositions comprising a liquid silicone and ester mixture |
| CN1339579A (en) * | 2001-10-10 | 2002-03-13 | 常耀辉 | Water base micro emulsion cleaning agent for heavy oil pollution and its prepn |
| CN104284650A (en) * | 2012-02-10 | 2015-01-14 | 斯蒂潘公司 | Structured surfactant suspending systems |
| CN107929168A (en) * | 2017-12-28 | 2018-04-20 | 江南大学 | A kind of moisturizing betaplex gentle cleansing milk |
| CN109620747A (en) * | 2018-12-28 | 2019-04-16 | 江南大学 | A kind of preparation method of the high viscoelastic surfactant vermiculate glues with pH response |
Non-Patent Citations (3)
| Title |
|---|
| "α-羧基氧化胺表面活性剂的pH响应自组装行为研究";张萌;《中国优秀硕士学位论文全文数据库 工程科技Ⅰ辑》;20180215;B014-1155 * |
| "表面活性剂水凝胶形成机理、刺激响应性质与应用研究";宋沙沙;《中国博士学位论文全文数据库 工程科技Ⅰ辑》;20150115;B014-226 * |
| 宋沙沙."表面活性剂水凝胶形成机理、刺激响应性质与应用研究".《中国博士学位论文全文数据库 工程科技Ⅰ辑》.2015,B014-226. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110201601A (en) | 2019-09-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7308247B2 (en) | High alcohol content foamable composition containing a silicone-based surfactant | |
| EP1668105B1 (en) | High alcohol content gel-like and foaming compositions | |
| EP2026650B1 (en) | Anti-microbial compositions | |
| JP2011136995A (en) | Fragrance microemulsion composition | |
| JP2001518943A (en) | Antibacterial, mild rinse-off liquid cleaning composition containing salicylic acid | |
| KR20010034019A (en) | Novel quaternary ammonuim compounds, compositions containing them, and uses thereof | |
| JP2008517051A (en) | Flavor and fragrance solubilization systems | |
| CN110283671B (en) | Aqueous aroma-enhancing composition | |
| CN110201601B (en) | Composition formed by induction of oily components | |
| MXPA02003127A (en) | Acidic light duty liquid cleaning compositions. | |
| JP7254718B2 (en) | Aqueous microemulsion | |
| Al‐Sabagh et al. | Synthesis of ethoxylated alkyl sulfosuccinate surfactants and the investigation of mixed solutions | |
| CN110305741B (en) | Self-thickening composition containing oily components | |
| EP3416612A1 (en) | Fragrant mixtures containing esters and ketones | |
| EP2276453A1 (en) | Solubilizing agent for essential oils and/or fragrances | |
| CN103987360A (en) | Transparent aqueous fragrance microemulsions | |
| KR20030082471A (en) | Sulfuric acid amine salt, sulfonic acid amine salt, production thereof and softener composition | |
| JP2022069782A (en) | Insect pest repellent composition for fiber treatment | |
| JP5921831B2 (en) | Tobacco odor deodorant | |
| JP2003105091A (en) | Manufacturing method of endoplasmic reticulum dispersant, endoplasmic reticulum dispersant and soft finishing agent for clothes | |
| JPH02157035A (en) | Microemulsion | |
| JP2005170854A (en) | Antibacterial agent and antibacterial composition | |
| MXPA06005471A (en) | Blooming natural oil cleaning compositions |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |