CN110200977A - The anti-infective treatment fluid of medical catheter and its preparation method, processing method, production method and the medical catheter of medical catheter - Google Patents
The anti-infective treatment fluid of medical catheter and its preparation method, processing method, production method and the medical catheter of medical catheter Download PDFInfo
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- CN110200977A CN110200977A CN201910464070.5A CN201910464070A CN110200977A CN 110200977 A CN110200977 A CN 110200977A CN 201910464070 A CN201910464070 A CN 201910464070A CN 110200977 A CN110200977 A CN 110200977A
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- Prior art keywords
- medical catheter
- treatment fluid
- antibacterials
- medical
- catheter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
Abstract
The present invention relates to a kind of anti-infective treatment fluid of medical catheter and its preparation method, a kind of processing method of medical catheter, production method and medical catheters, are related to field of medical technology；The anti-infective treatment fluid includes organic solvent and antibacterials；The organic solvent includes methanol, and the antibacterials are one of rifampin, minocycline hydrochloride or two kinds of combination；The content of the antibacterials are as follows: rifampin: 0~300mg/ml, minocycline hydrochloride: 0~300mg/ml；Treatment fluid of the invention is prepared simply, and content of dispersion is high, and drug effect is long, good anti-bacterial effect.
Description
" technical field "
The present invention relates to field of medical technology, more particularly to a kind of anti-infective treatment fluid of medical catheter and its preparation side
Method, a kind of processing method of medical catheter, production method and medical catheter.
" background technique "
Medical catheter is very extensive in clinical application, especially embedded type conduit, such as catheter, and tracheal catheter or tracheae are made
Mouth conduit and blood vessel interposing catheter.Since there are certain roughness on microcosmic for this kind of catheter surface, in clinical use mistake
Because using the extension of time in journey, be easy to cause each quasi-microorganism in the field planting of catheter surface, and certain catheter surface occur it is micro-
Biology field planting, especially staphylococcus (staphylococcus aureus, staphylococcus epidermis, micrococcus scarlatinae), Escherichia coli, leather
The field planting of the common pathogens such as Lan Shi feminine gender aerobasilus and Pseudomonas aeruginosa will lead to plant pipe patient and conduit source sexuality occurs
Dye, length of patient stay extends and treatment cost is significantly increased, and causes septicemia even dead when serious.
For such conduit source property infection risk, all kinds of medical instrument manufacturers have developed all kinds of medical use anti-infection conduits,
Some manufacturers are using anti-infectives and conduit material coextrusion processes, but this method and process is complicated, and how antibacterials mix
It closes unevenly, may cause regional catheter does not have antibacterial effect, and antibacterial effect is poor；Some manufacturers use catheter surface graft modification
Technique, although antibacterial effect is preferable, complex process, high production cost, therefore will cause clinical application cost height, give patient
Bring financial burden；Manufacturer also uses catheter surface anti-infectives coating process, but be easy to cause smearing uneven, and
And catheter inside surface the problem of can not smearing；This above-mentioned all kinds of anti-infectious catheter technique is realized clinical application and few at present,
In addition the anti-infectious catheter of the also relatively common flamazine process for having arrow company, the U.S., because silver ion exists
Certain security risk, clinical field have gradually decreased the application of this kind of medical use anti-infection conduit of silver ion.It can be seen from the above, working as
The other kinds anti-infectious catheter of preceding clinical application or there are production technology complexity, or ask there are clinical application cost is higher etc.
Topic.
" summary of the invention "
The first object of the present invention is intended to provide a kind of anti-infective treatment fluid of medical catheter of good anti-bacterial effect；The present invention is logical
Cross following technical scheme realization:
A kind of anti-infective treatment fluid of medical catheter, which is characterized in that including organic solvent and antibacterials；It is described organic
Solvent includes methanol, and the antibacterials are one of rifampin, minocycline hydrochloride or two kinds of combination；The antimicrobial
The content of object are as follows:
Rifampin: 0~300mg/ml,
Minocycline hydrochloride: 0~300mg/ml；Wherein the content of rifampin and minocycline hydrochloride is not 0 simultaneously.
Further, the organic solvent further includes component A, and the component A is ethyl acetate or butyl acetate, wherein institute
The volume ratio for stating methanol and the component A is 1: 0~1: 6.
Preferably, the content of the minocycline hydrochloride is 0~100mg/ml.
The second object of the present invention is intended to provide a kind of preparation method of anti-infective treatment fluid of medical catheter, has treatment fluid
Convenient advantage is prepared, the second object of the present invention is implemented with the following technical solutions.
The preparation method of the anti-infective treatment fluid of medical catheter described in a kind of first purpose, which is characterized in that including following
Step:
S1: each component of the treatment fluid is measured by recipe requirements；
S2: organic solvent is poured into sterile liquid mixing bottle；When organic solvent includes two kinds, the sequence of pouring into of each does not have
It is required that；
S3: it is slowly added to load weighted antibacterials in step S1 in the sterile liquid mixing bottle and is stirred, to institute
Antibacterials are stated to be added completely into and dissolve；
S4: the anti-infective treatment fluid of prepared medical catheter is kept in dark place.
Further, step S3 further includes after the antibacterials are added completely into and dissolve, continuing stirring 3~5 minutes,
To ensure that drug is uniformly mixed.
Specifically, step S3 is specifically included: device used in the stirring is magnetic stirring apparatus；The antimicrobial is added
Before object, first the sterile liquid mixing bottle is put on the magnetic stirring apparatus.
The third object of the present invention is intended to provide a kind of processing method of medical catheter, and the processing method process is simple, can
Strong operability, the third object of the present invention are implemented with the following technical solutions.
A kind of processing method of medical catheter, which is characterized in that the treating method comprises following steps:
S1: under dark room conditions, the medical catheter main body is soaked into the processing as described in the first object of the present invention
In liquid, certain time is impregnated, the medical catheter fully enters the treatment fluid, bubble-free in the medical catheter pipe；
S2: taking out the medical catheter and dries in draught cupboard；
S3: the medical catheter is inserted in be protected from light in bag and is kept in dark place.
Specifically, the soaking time of medical catheter described in step S1 is 10min~4h.
The fourth object of the present invention is intended to provide a kind of production method of medical catheter, and the production method process is simple, can
Strong operability, the fourth object of the present invention are implemented with the following technical solutions.
A kind of production method of medical catheter, including extrusion molding process, which is characterized in that in the extrusion molding process
Later include soaking technology, the soaking technology the following steps are included:
S1: treatment fluid described in the first object of the present invention is poured into a drug slot；
S2: the medical catheter of extrusion molding is directly placed in the drug slot, and is immersed in the treatment fluid, is impregnated certain
Time, certain time is impregnated, the medical catheter fully enters the treatment fluid, bubble-free in the medical catheter pipe；
S3: it takes out the medical catheter and dries；
S4: it is kept in dark place after the medical catheter is cut into design length.
Specifically, in step S2, the soaking time of the medical catheter is 10min~4h.
Further, the drug slot is equipped with a shading cover.
Further, on the matching piece of the drug slot installation in the production line, the drug slot and the matching piece are removable
Unload connection.
In the present invention, the drug slot is removable to be unloaded down, when needing to produce the medical catheter containing antibacterials, peace
Projectile filling groove implements soaking technology described above；When needing to produce plain edition medical catheter (no antibacterials), drug slot is torn open
It unloads down, sink is installed, for the conduit of extrusion molding to be impregnated cooling；It can thus be appreciated that same production line can either produce commonly
Type medical catheter, and it is able to produce the medical catheter containing antibacterials, and dismountable drug slot structure can facilitate plain edition to cure
It is produced with conduit with the conversion of the medical catheter containing antibacterials, production cost can be effectively reduced.
The fifth object of the present invention is intended to provide a kind of medical catheter, and the production method process of the application catheter is simple, can
The anti-microbial property of strong operability, the medical catheter is high, and the fifth object of the present invention is implemented with the following technical solutions.
A kind of medical catheter, which is characterized in that the medical catheter is using the third object of the present invention processing method institute
Processed medical catheter；
Or the medical catheter is the fourth object of the present invention production method medical catheter produced.
Advantageous effects of the invention: treatment fluid of the invention prepares simple, content of dispersion height, and drug effect is long；Of the invention
It is simple to handle liquid making method process, it is low in cost；The processing method and production method process letter of medical catheter of the invention
Single, the inner wall outer wall that can be operated by force, and pass through the medical catheter for handling or producing, which loads, antibacterials, antibacterials point
Cloth is uniform, good anti-bacterial effect.
" Detailed description of the invention "
Fig. 1 is the preparation process figure for the anti-infective treatment fluid that the embodiment of the present invention one~tetra- provides.
" specific embodiment "
In order to which technical solution of the present invention is more clearly understood, the present invention is made furtherly with reference to embodiments
Bright, specific embodiment, which is only limitted to facilitate, explains that the solution of the present invention content, the content that the present invention protects are not limited to specific embodiment
The content of announcement.
A kind of anti-infective treatment fluid of medical catheter, the treatment fluid include organic solvent and antibacterials；It is described organic molten
Agent includes methanol, and the antibacterials are one of rifampin, minocycline hydrochloride or two kinds of combination；The organic solvent
It further include ethyl acetate or butyl acetate.
Embodiment one
The formula of the anti-infective treatment fluid of the medical catheter of the present embodiment is as follows:
The volume ratio of MeOH methanol and ethyl acetate is 1: 0,
Rifampin: 10 ㎎/ml,
Minocycline hydrochloride: 0 ㎎/ml；
With reference to Fig. 1, the process for preparation of the treatment fluid the following steps are included:
S1: measuring the methanol of suitable volumes with measuring cup in proportion, weighs suitable rifampin by recipe requirements；
S2: the methanol of measurement is poured into sterile liquid mixing bottle；
S3: will pour into the sterile liquid mixing bottle of methanol, be placed on magnetic stir plate, be put into magnetic stir bar to liquid
In bottle, magnetic stirring apparatus is opened, load weighted antibacterials in step S1 is slowly added to, is added completely into all antibacterials
After organic solvent and dissolution, continue stirring 3~5 minutes, it is ensured that drug is uniformly mixed；
S4: the anti-infective treatment fluid of prepared medical catheter is kept in dark place, spare.
Embodiment two
The formula of the anti-infective treatment fluid of the medical catheter of the present embodiment is as follows:
The volume ratio of methanol and ethyl acetate is 1: 0,
Rifampin: 100 ㎎/ml,
Minocycline hydrochloride: 100 ㎎/ml；
With reference to Fig. 1, the process for preparation of the treatment fluid the following steps are included:
S1: measuring the methanol of suitable volumes with measuring cup in proportion, weighs suitable rifampin and hydrochloric acid rice by recipe requirements
Promise ring element；
S2: the methanol of measurement is poured into sterile liquid mixing bottle；
S3: will pour into the sterile liquid mixing bottle of methanol, be placed on magnetic stir plate, be put into magnetic stir bar to liquid
In bottle, magnetic stirring apparatus is opened, load weighted antibacterials in step S1 is slowly added to, is added completely into all antibacterials
After organic solvent and dissolution, continue stirring 3~5 minutes, it is ensured that drug is uniformly mixed；
S4: the anti-infective treatment fluid of prepared medical catheter is kept in dark place, spare.
Embodiment three
The formula of the anti-infective treatment fluid of the medical catheter of the present embodiment is as follows:
The volume ratio of methanol and ethyl acetate is 1: 6,
Rifampin: 100 ㎎/ml,
Minocycline hydrochloride: 100 ㎎/ml；
In still another embodiment, ethyl acetate can be replaced with butyl acetate.
With reference to Fig. 1, the process for preparation of the treatment fluid the following steps are included:
S1: measuring the methanol and ethyl acetate of suitable volumes with measuring cup in proportion, weighs suitable sharp good fortune by recipe requirements
Gentle minocycline hydrochloride；
S2: the methanol of measurement and ethyl acetate are poured into sterile liquid mixing bottle, and methanol and ethyl acetate pour into sequence without spy
It is different to require；
S3: the sterile liquid mixing bottle of methanol and ethyl acetate will be poured into, is placed on magnetic stir plate, is put into magnetic force and stirs
Son is mixed into liquid mixing bottle, magnetic stirring apparatus is opened, load weighted antibacterials in step S1 is slowly added to, to all antimicrobials
After object is added completely into organic solvent and dissolves, continue stirring 3~5 minutes, it is ensured that drug is uniformly mixed；
S4: the anti-infective treatment fluid of prepared medical catheter is kept in dark place, spare.
Example IV
The formula of the anti-infective treatment fluid of the medical catheter of the present embodiment is as follows:
The volume ratio of methanol and ethyl acetate is 1: 6,
Rifampin: 300 ㎎/ml,
Minocycline hydrochloride: 300 ㎎/ml；
In still another embodiment, ethyl acetate can be replaced with butyl acetate.
With reference to Fig. 1, the process for preparation of the treatment fluid the following steps are included:
S1: measuring the methanol and ethyl acetate of suitable volumes with measuring cup in proportion, weighs suitable sharp good fortune by recipe requirements
Gentle minocycline hydrochloride；
S2: the methanol of measurement and ethyl acetate are poured into sterile liquid mixing bottle, and methanol and ethyl acetate pour into sequence without spy
It is different to require；
S3: the sterile liquid mixing bottle of methanol and ethyl acetate will be poured into, is placed on magnetic stir plate, is put into magnetic force and stirs
Son is mixed into liquid mixing bottle, magnetic stirring apparatus is opened, load weighted antibacterials in step S1 is slowly added to, to all antimicrobials
After object is added completely into organic solvent and dissolves, continue stirring 3~5 minutes, it is ensured that drug is uniformly mixed；
S4: the anti-infective treatment fluid of prepared medical catheter is kept in dark place, spare.
Embodiment five
A kind of medical catheter processing method, comprising the following steps:
S1: under dark room conditions, it is anti-infective that medical catheter main body is soaked into medical catheter described in the various embodiments described above
In treatment fluid, one end time is impregnated；Soaking time is generally 10min~4h；The present embodiment impregnates 4h；
S2: soaked medical catheter is taken out, is dried in draught cupboard.
S3: it will be inserted in be protected from light in bag and save through S2 treated medical catheter.
The processing that the processing method is suitable for finished product medical catheter is impregnated.
Embodiment six
A kind of production method of medical catheter, including extrusion molding process, locating extrusion molding process further include leaching later
Bubble technique, the soaking technology the following steps are included:
S1: treatment fluid of the embodiment one to four described in any one is poured into a drug slot；
S2: the medical catheter of extrusion molding is directly placed in the drug slot, and is immersed in the treatment fluid, described medical
Conduit fully enters the treatment fluid, bubble-free in the medical catheter pipe；Soaking time is generally 10min~4h；The medicine
Slot is equipped with a shading cover, for guaranteeing that soaking technology carries out under shading environment；
S3: it takes out the medical catheter and dries；
S4: it is kept in dark place after the medical catheter is cut into design length.
The production method is suitable for a kind of technique of the medical catheter in process of production, in conduit extrusion molding process
A kind of technique afterwards.
Further, on the matching piece of the drug slot installation in the production line, the drug slot and the matching piece are removable
Unload connection.
In the present invention, the drug slot be it is dismountable, when needing to produce medical catheter containing antibacterials, medicine is installed
Slot implements soaking technology described above；When needing to produce plain edition medical catheter (no antibacterials), drug slot is dismantled down
Come, sink is installed, for the conduit of extrusion molding to be impregnated cooling；It can thus be appreciated that same production line can either produce plain edition doctor
With conduit, and it is able to produce the medical catheter containing antibacterials, and dismountable drug slot structure can facilitate plain edition is medical to lead
The conversion production of pipe and the medical catheter containing antibacterials, can effectively reduce production cost.
The above description is only a preferred embodiment of the present invention, is not intended to restrict the invention, for those skilled in the art
For member, the invention may be variously modified and varied.All within the spirits and principles of the present invention, without made by creativeness
Any modification, equivalent substitution, improvement and etc. should all be included in the protection scope of the present invention.
Claims (13)
1. a kind of anti-infective treatment fluid of medical catheter, which is characterized in that including organic solvent and antibacterials；It is described organic molten
Agent includes methanol, and the antibacterials are one of rifampin, minocycline hydrochloride or two kinds of combination；The antibacterials
Content are as follows:
Rifampin: 0~300mg/ml,
Minocycline hydrochloride: 0~300mg/ml.
2. the anti-infective treatment fluid of medical catheter according to claim 1, which is characterized in that the organic solvent further includes group
Dividing A, the component A is ethyl acetate or butyl acetate, wherein the volume ratio of the methanol and the component A are 1: 0~1: 6.
3. the anti-infective treatment fluid of medical catheter according to claim 1 or 2, which is characterized in that the minocycline hydrochloride
Content be 0~100mg/ml.
4. a kind of preparation method for the treatment of fluid described in claims 1 to 3 any one, which comprises the following steps:
S1: each component of the treatment fluid is measured by recipe requirements；
S2: organic solvent is poured into sterile liquid mixing bottle；The organic solvent each component is put into sequence no requirement (NR)；
S3: being slowly added to load weighted antibacterials in step S1 and be stirred in the sterile liquid mixing bottle, to described anti-
Bacterium drug is added completely into and dissolves；
S4: the anti-infective treatment fluid of prepared medical catheter is kept in dark place.
5. preparation method according to claim 4, which is characterized in that step S3 further includes that the antibacterials add completely
After entering and dissolving, continue stirring 3~5 minutes, it is ensured that drug is uniformly mixed.
6. preparation method according to claim 4 or 5, which is characterized in that step S3 is specifically included: the stirring is used
Device be magnetic stirring apparatus；Before the antibacterials are added, first the sterile liquid mixing bottle is put on the magnetic stirring apparatus.
7. a kind of processing method of medical catheter, which is characterized in that the treating method comprises following steps:
S1: under dark room conditions, the medical catheter main body is soaked into the processing as described in claims 1 to 3 any one
In liquid, certain time is impregnated, the medical catheter fully enters the treatment fluid, bubble-free in the medical catheter pipe；
S2: taking out the medical catheter and dries in draught cupboard；
S3: the medical catheter is inserted in be protected from light in bag and is kept in dark place.
8. the processing method of medical catheter according to claim 7, which is characterized in that medical catheter described in step S1
Soaking time is 10min~4h.
9. a kind of production method of medical catheter, including extrusion molding process, which is characterized in that the extrusion molding process it
Afterwards include soaking technology, the soaking technology the following steps are included:
S1: treatment fluid described in the claims 1 to 3 any one is poured into a drug slot；
S2: the medical catheter of extrusion molding is directly placed in the drug slot, and is immersed in the treatment fluid, and a timing is impregnated
Between, the medical catheter is totally immersed into the treatment fluid, bubble-free in the medical catheter pipe；
S3: it takes out the medical catheter and dries；
S4: it is kept in dark place after the medical catheter is cut into design length.
10. the production method of medical catheter according to claim 9, which is characterized in that in step S2, the medical catheter
Soaking time be 10min~4h.
11. the production method of medical catheter according to claim 8 or claim 9, which is characterized in that the drug slot is equipped with a shading
Lid, the shading are placed on the opening of the drug slot.
12. the production method of medical catheter according to claim 8 or claim 9, which is characterized in that the drug slot is mounted on production
On a matching piece on line, the drug slot is detachably connected with the matching piece.
13. a kind of medical catheter, which is characterized in that the medical catheter is using the institute of processing method described in claim 7 or 8
Processed medical catheter；
Or the medical catheter is medical to lead using production method described in claim 9~12 any one is produced
Pipe.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910464070.5A CN110200977A (en) | 2019-05-30 | 2019-05-30 | The anti-infective treatment fluid of medical catheter and its preparation method, processing method, production method and the medical catheter of medical catheter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910464070.5A CN110200977A (en) | 2019-05-30 | 2019-05-30 | The anti-infective treatment fluid of medical catheter and its preparation method, processing method, production method and the medical catheter of medical catheter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110200977A true CN110200977A (en) | 2019-09-06 |
Family
ID=67789663
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|---|---|---|---|
| CN201910464070.5A Withdrawn CN110200977A (en) | 2019-05-30 | 2019-05-30 | The anti-infective treatment fluid of medical catheter and its preparation method, processing method, production method and the medical catheter of medical catheter |
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| CN (1) | CN110200977A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102365102A (en) * | 2009-02-02 | 2012-02-29 | 麦德托尼克公司 | Antimicrobial accessory for an implantable medical device |
| CN102500033A (en) * | 2011-11-04 | 2012-06-20 | 北京迪玛克医药科技有限公司 | Anti-infection venous catheter and preparation method thereof |
| CN105431178A (en) * | 2013-11-08 | 2016-03-23 | 泰尔克斯公司 | Antimicrobial compositions and methods for preventing infection in surgical incision sites |
-
2019
- 2019-05-30 CN CN201910464070.5A patent/CN110200977A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102365102A (en) * | 2009-02-02 | 2012-02-29 | 麦德托尼克公司 | Antimicrobial accessory for an implantable medical device |
| CN102500033A (en) * | 2011-11-04 | 2012-06-20 | 北京迪玛克医药科技有限公司 | Anti-infection venous catheter and preparation method thereof |
| CN105431178A (en) * | 2013-11-08 | 2016-03-23 | 泰尔克斯公司 | Antimicrobial compositions and methods for preventing infection in surgical incision sites |
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