CN110200162A - A kind of groove feed for pigling adjusting intestinal epithelial cell and intestinal growth - Google Patents

A kind of groove feed for pigling adjusting intestinal epithelial cell and intestinal growth Download PDF

Info

Publication number
CN110200162A
CN110200162A CN201910610544.2A CN201910610544A CN110200162A CN 110200162 A CN110200162 A CN 110200162A CN 201910610544 A CN201910610544 A CN 201910610544A CN 110200162 A CN110200162 A CN 110200162A
Authority
CN
China
Prior art keywords
parts
intestinal
epithelial cell
pigling
growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910610544.2A
Other languages
Chinese (zh)
Inventor
杨焕胜
印遇龙
李建中
熊霞
李雅丽
丁雪沁
黄鹏飞
王启业
尹佳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hunan Normal University
Institute of Subtropical Agriculture of CAS
Original Assignee
Hunan Normal University
Institute of Subtropical Agriculture of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hunan Normal University, Institute of Subtropical Agriculture of CAS filed Critical Hunan Normal University
Priority to CN201910610544.2A priority Critical patent/CN110200162A/en
Publication of CN110200162A publication Critical patent/CN110200162A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/163—Sugars; Polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings

Abstract

The present invention discloses the groove feed for pigling of a kind of update of adjusting intestinal epithelial cell and promotion intestinal growth, it is matched in parts by weight by following substance: 35.0-37.0 parts of corn, 20.0-22.0 parts of popcorn, 43% 7.0-9.0 parts of dregs of beans, 4.0-6.0 parts of the concentrated albumen-powder of soybeans, 8.0-12.0 parts of whey powder, 63% 4.0-6.0 parts of fish meal, 4.0-5.0 parts of plasma protein powder, 0.4-0.5 parts of lysine, 0.2-0.24 parts of DL- METHIONINE, 0.07-0.1 parts of threonine, 0.07-0.08 parts of tryptophan, 2.0-3.0 parts of glucose, 1.0-3.0 parts of soya-bean oil, 0.8-1.1 parts of mountain flour, 0.4-0.6 parts of calcium monohydrogen phosphate, zinc oxide 0.12-0 .16 part, 1.0-1.5 parts of concentration of fibre, 0.08-0.1 parts of niacin pre-mixing agent, 0.1-0.15 parts of cell factor pre-mixing agent, 1.0 parts of sucking pig premix, adds up to 100 parts by 1.0-1.5 parts of citric acid.For this creep feed according to the Nutrition and Metabolism feature of intestine of young pigs epithelial cell turnover, science chooses raw material and setting raw material proportioning, can effectively adjust intestine of young pigs epithelial cell turnover, promotes intestine of young pigs development.

Description

A kind of groove feed for pigling adjusting intestinal epithelial cell and intestinal growth
Technical field
The present invention relates to pannage fields more particularly to a kind of piglet for adjusting intestinal epithelial cell and intestinal growth to teach slot Material.
Background technique
China is both Animal husbandry production big country and Consumption of animal by-product big country.China is current pork maximum in the world 50% or more of production and country of consumption, China's live pig amount of delivering for sale and the world pork consumption Jun Zhan.However, China is not growth The problems such as cultivation power, pig-breeding inefficiency, feed resource shortage and environmental pollution, seriously restricts China's pig-breeding The sustainable health development of industry.Bowel problems are to influence the critical issue of our pig-breeding benefits, not only influence survival of piglets Rate and growth and development, while having an effect on the lifelong food utilization efficiency of pig.Intestinal epithelial cell is the main execution of function of intestinal canal Quick update of person, intestinal epithelial cell are the bases for maintaining intestinal health and ensureing intestinal growth.However, intestine of young pigs epithelium The correct update of cell is influenced by factors such as weaning stress, intestinal inflammatory, oxidative damage and nutrition supplies, serious shadow Intestine of young pigs health and development are rung.Although groove feed for pigling technology is ground with the development of China's feed industry and animal husbandry Study carefully and using achieving huge progress, but it is still insufficient for the understanding of intestine of young pigs epithelial cell turnover.The prior art In can not adjust intestine of young pigs epithelial cell turnover and thus promote intestinal growth creep feed.
Summary of the invention
The primary purpose of the present invention is that overcome defect of the existing technology, a kind of adjusting intestinal epithelial cell is provided more Groove feed for pigling that is new and promoting intestinal growth.
In order to achieve the above objectives, solution of the invention is:
A kind of groove feed for pigling for adjusting intestinal epithelial cell and updating and promoting intestinal growth, by weight by following substance Number matches:
Corn 35.0-37.0 parts
Popcorn 20.0-22.0 parts
43% dregs of beans 7.0-9.0 part
The concentrated albumen-powder of soybeans 4.0-6.0 part
Whey powder 8.0-12.0 part
63% fish meal 4.0-6.0 part
Plasma protein powder 4.0-5.0 part
Lysine 0.4-0.5 parts
DL- METHIONINE 0.2-0.3 parts
Threonine 0.07-0.1 parts
Tryptophan 0.06-0.08 parts
Glucose 2.0-3.0 part
Soya-bean oil 1.0-3.0 part
Mountain flour 0.8-1.1 parts
Calcium monohydrogen phosphate 0.4-0.6 parts
Zinc oxide 0.12-0.16 parts
Citric acid 1.0-1.5 part
Concentration of fibre 1.0-1.5 part
Niacin pre-mixing agent 0.08-0.1 parts
Cell factor pre-mixing agent 0.1-0.15 parts
Sucking pig premix 1.0 part
Wherein, lysine in the creep feed: sulfur-containing amino acid: the ratio of tryptophan is 100:63:19；The cigarette Nicotinic Acid Content is 1% in sour pre-mixing agent, sulfur-containing amino acid=methionine+cysteine；The cell factor pre-mixing agent is by table Skin cell growth factor (EGF) and glucagon-like peptide 2 (GLP-2) group, wherein the content of EGF is 400mg/kg, GLP-2's Content is 600mg/kg, and the two weight ratio is 4:6.
Preferably, it is made of following weight fraction proportion:
。
The present invention have the advantage that and the utility model has the advantages that
(1) the Nutrition and Metabolism feature that the present invention is updated according to intestine of young pigs epithelial cell crypt-villus axis, scientific offering ammonia The trophic level such as base acid and vitamin and ratio adjust intestinal epithelial cell and update, and promote intestine of young pigs development；
(2) component in creep feed provided by the invention: cell factor can adjust the Proliferation, Differentiation of intestinal epithelial cell, dense The update of enterocyte after the short chain fatty acids such as the shrinkage fibers butyric acid that rear intestinal fermentation generates again can be adjusted effectively, to adjust Save the epithelial cell turnover and intestinal growth of the entire enteron aisle of piglet；
(3) creep feed provided by the invention can improve the entire growth cycle of pig by the intestinal growth of improvement piglet Nutrient digestion absorption efficiency reduces breeding waste discharge, meets ecologic breeding theory while improving culture efficiency；
(4) raw material components of the present invention are easy to get, at low cost.
Specific embodiment
Embodiment 1
A kind of groove feed for pigling for adjusting intestinal epithelial cell and updating and promoting intestinal growth, material composition and proportion are shown in Table 1.
Each substance of groove feed for pigling matches table in 1 embodiment 1-5 of table
Material name Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4 Embodiment 5
Corn 35.08 parts 35 parts 37 parts 36.33 parts 36.65 parts
Popcorn 22 parts 21.15 parts 20.74 parts 21 parts 20 parts
43% dregs of beans 7 parts 8.1 part 7.9 part 6 parts 9 parts
The concentrated albumen-powder of soybeans 6 parts 5.1 part 4.9 part 5 parts 4 parts
Whey powder 12 parts 10.2 parts 9.8 part 11 parts 8 parts
63% fish meal 4 parts 5.1 part 4.9 part 5.5 part 6 parts
Plasma protein powder 4 parts 4.5 part 4.4 part 4.5 part 5 parts
Lysine 0.5 part 0.45 part 0.44 part 0.45 part 0.4 part
DL- METHIONINE 0.24 part 0.22 part 0.21 part 0.22 part 0.2 part
Threonine 0.1 part 0.09 part 0.08 part 0.09 part 0.07 part
Tryptophan 0.08 part 0.07 part 0.07 part 0.07 part 0.07 part
Glucose 3 parts 2.5 part 2.4 part 2.8 part 2 parts
Soya-bean oil 1 part 2.1 part 1.9 part 1.5 part 3 parts
Mountain flour 0.8 part 0.95 part 0.93 part 0.87 part 1.1 part
Calcium monohydrogen phosphate 0.4 part 0.51 part 0.49 part 0.5 part 0.6 part
Zinc oxide 0.12 part 0.14 part 0.14 part 0.14 part 0.16 part
Citric acid 1.5 part 1.3 part 1.23 part 1.4 part 1 part
Concentration of fibre 1 part 1.3 part 1.26 part 1.4 part 1.5 part
Niacin pre-mixing agent 0.08 part 0.09 part 0.09 part 0.09 part 0.1 part
Cell factor pre-mixing agent 0.1 part 0.13 part 0.12 part 0.14 part 0.15 part
Sucking pig premix 1 part 1 part 1 part 1 part 1 part
It is total 100 parts 100 parts 100 parts 100 parts 100 parts
The niacin pre-mixing agent is mixed by niacin and zeolite powder according to the mass ratio of 1:10；Cell factor pre-mixing agent It is mixed respectively according to 400mg/kg and 600mg/kg ratio with rice bran meal by EGF and GLP-2；Sucking pig premix is by Hunan grain Rich Biotechnology Co., Ltd provides.
Embodiment 2
A kind of groove feed for pigling for adjusting intestinal epithelial cell and updating and promoting intestinal growth, material composition and proportion are shown in Table 1.
Embodiment 3
A kind of groove feed for pigling for adjusting intestinal epithelial cell and updating and promoting intestinal growth, material composition and proportion are shown in Table 1.
Embodiment 4
A kind of groove feed for pigling for adjusting intestinal epithelial cell and updating and promoting intestinal growth, material composition and proportion are shown in Table 1.
Embodiment 5
A kind of groove feed for pigling for adjusting intestinal epithelial cell and updating and promoting intestinal growth, material composition and proportion are shown in Table 1.
Application effect appraisal
24 age in days weanling pigs (Du × length × big) 270 are chosen, assign to group at 3 at random by weight and gender: control Group I and control Group II feeding conventional market sell creep feed；The creep feed of experimental group feeding embodiment 3.Every group of 5 repetitions, often 18 pigs of a repetition, experimental period 14 days.Piglet 1 is randomly selected in the 38 every repetitions of age in days each group, enteron aisle organ is used for after butchering Index, intestinal epithelial cell proliferation and intestinal structure analysis.From table 2 it can be seen that selling creep feed phase containing conventional market Than creep feed of the invention can increase the weight and length of small intestine and large intestine.Creep feed of the present invention can as can be seen from Table 3 Remarkably promote weanling pig jejunum row ileal epithelium proliferation.It can be seen that creep feed of the present invention exists from the test result of table 4 It can be improved the ratio of Jejunum of Piglets villi height and height of naps and Crypt depth to a certain extent.The above result shows that Weanling pig, which feeds creep feed of the present invention, can improve the update of intestine of young pigs epithelial cell proliferation and intestinal structure, promote intestines Road development.
Influence of the different daily rations of table 2 to weanling pig enteron aisle shoot formation
Project Control group I Control Group II Test group
Small intestine weight (g/kg weight) 35.20 34.63 41.37
Small intestinal length (m/kg weight) 1.31 1.20 1.39
Large intestine weight (g/kg weight) 13.23 12.56 15.23
Large intestine length (m/kg weight) 0.16 0.20
Influence of the different daily rations of table 3 to weanling pig Intestinal epitheliual cell proliferation index
Project Control group I Control Group II Test group
Jejunum 295.52 270.58 420.90
Ileum 255.56 241.54 324.69
Influence of the different daily rations of table 4 to weanling pig jejunum intestinal structure
Project Control group I Control Group II Test group
Height of naps (μm) 219.15 201.25 243.16
Crypt depth (μm) 176.74 166.33 184.22
Height of naps: Crypt depth 1.24 1.21 1.32
。

Claims (6)

1. a kind of groove feed for pigling for adjusting intestinal epithelial cell and intestinal growth, which is characterized in that with total amount for 100 parts by weight It calculates, the creep feed includes each component of following parts by weight:
Corn 35.0-37.0 parts Popcorn 20.0-22.0 parts 43% dregs of beans 7.0-9.0 part The concentrated albumen-powder of soybeans 4.0-6.0 part Whey powder 8.0-12.0 part 63% fish meal 4.0-6.0 part Plasma protein powder 4.0-5.0 part Lysine 0.4-0.5 parts DL- METHIONINE 0.2-0.24 parts Threonine 0.07-0.1 parts Tryptophan 0.07-0.08 parts Glucose 2.0-3.0 part Soya-bean oil 1.0-3.0 part Mountain flour 0.8-1.1 parts Calcium monohydrogen phosphate 0.4-0.6 parts Zinc oxide 0.12-0.16 parts Citric acid 1.0-1.5 part Concentration of fibre 1.0-1.5 part Niacin pre-mixing agent 0.08-0.1 parts Cell factor pre-mixing agent 0.1-0.15 parts Sucking pig premix 1.0 part
。
2. adjusting the groove feed for pigling of intestinal epithelial cell and intestinal growth as described in claim 1, which is characterized in that described Creep feed include following parts by weight each component:
。
3. the groove feed for pigling of adjusting intestinal epithelial cell and intestinal growth as described in claims 1 or 2 any claim, It is characterized in that, Nicotinic Acid Content is 1% in the niacin pre-mixing agent.
4. the groove feed for pigling of adjusting intestinal epithelial cell and intestinal growth as described in claims 1 or 2 any claim, It is characterized in that, the cell factor pre-mixing agent includes epithelical cell growth factor and glucagon-like peptide 2.
5. adjusting the groove feed for pigling of intestinal epithelial cell and intestinal growth as claimed in claim 4, which is characterized in that wherein Epithelical cell growth factor pre-mixing agent and glucagon-like peptide 2 are respectively 400mg/kg and 600mg/ in the middle specific gravity of premix kg。
6. the groove feed for pigling of adjusting intestinal epithelial cell and intestinal growth as described in claims 1 or 2 any claim, It is characterized in that, the lysine: sulfur-containing amino acid: the weight ratio of tryptophan is 100:63:19.
CN201910610544.2A 2019-07-04 2019-07-04 A kind of groove feed for pigling adjusting intestinal epithelial cell and intestinal growth Pending CN110200162A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910610544.2A CN110200162A (en) 2019-07-04 2019-07-04 A kind of groove feed for pigling adjusting intestinal epithelial cell and intestinal growth

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910610544.2A CN110200162A (en) 2019-07-04 2019-07-04 A kind of groove feed for pigling adjusting intestinal epithelial cell and intestinal growth

Publications (1)

Publication Number Publication Date
CN110200162A true CN110200162A (en) 2019-09-06

Family

ID=67796631

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910610544.2A Pending CN110200162A (en) 2019-07-04 2019-07-04 A kind of groove feed for pigling adjusting intestinal epithelial cell and intestinal growth

Country Status (1)

Country Link
CN (1) CN110200162A (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011002298A2 (en) * 2009-07-03 2011-01-06 Nutreco Nederland B.V. Animal feed or human food for improving intestinal barrier properties
CN102178115A (en) * 2011-05-13 2011-09-14 成都华西希望农业科学技术研究所有限公司 Compound feed for teaching piglets to eat foods other than breast milk
CN102464642A (en) * 2010-11-18 2012-05-23 谢联金 Compound, preparation method thereof and application thereof as feed additive
CN102870993A (en) * 2012-10-10 2013-01-16 荆州双胞胎饲料有限公司 Compound feed additive for effectively improving intestinal canal health of pigs
CN104489413A (en) * 2015-01-13 2015-04-08 四川省畜牧科学研究院 Weaned piglet formula feed containing fiber resources
CN105614104A (en) * 2016-01-07 2016-06-01 漳州傲农牧业科技有限公司 Piggy creep feed containing composite flavone and preparation method thereof
CN106692948A (en) * 2016-11-16 2017-05-24 南宁学院 Immunopotentiator for piglets
CN106942496A (en) * 2017-04-21 2017-07-14 宁夏大北农科技实业有限公司 Improve grower pigs intestinal health and the accurate nutritious diet of low albumen of immunologic function

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011002298A2 (en) * 2009-07-03 2011-01-06 Nutreco Nederland B.V. Animal feed or human food for improving intestinal barrier properties
CN102464642A (en) * 2010-11-18 2012-05-23 谢联金 Compound, preparation method thereof and application thereof as feed additive
CN102178115A (en) * 2011-05-13 2011-09-14 成都华西希望农业科学技术研究所有限公司 Compound feed for teaching piglets to eat foods other than breast milk
CN102870993A (en) * 2012-10-10 2013-01-16 荆州双胞胎饲料有限公司 Compound feed additive for effectively improving intestinal canal health of pigs
CN104489413A (en) * 2015-01-13 2015-04-08 四川省畜牧科学研究院 Weaned piglet formula feed containing fiber resources
CN105614104A (en) * 2016-01-07 2016-06-01 漳州傲农牧业科技有限公司 Piggy creep feed containing composite flavone and preparation method thereof
CN106692948A (en) * 2016-11-16 2017-05-24 南宁学院 Immunopotentiator for piglets
CN106942496A (en) * 2017-04-21 2017-07-14 宁夏大北农科技实业有限公司 Improve grower pigs intestinal health and the accurate nutritious diet of low albumen of immunologic function

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘伯帅等: "饲粮纤维源对仔猪生长性能、肠道发育及其消化酶活性的影响", 《草业学报》 *
张高娜等: "影响断奶仔猪肠道发育的因素及营养调控措施", 《饲料广角》 *

Similar Documents

Publication Publication Date Title
CN103385379B (en) Laying duck complete feed
CN103689283B (en) Adult giant salamander feed and preparation method thereof
CN101449746B (en) Feedstuff for laying hens and use thereof in producing laying hens
Saki et al. Herbal additives and organic acids as antibiotic alternatives in broiler chickens diet for organic production
CN103141698B (en) Low-protein compound feed for geese
CN111513186B (en) Feed for improving muscle quality of groupers and preparation method thereof
CN108669358B (en) Health-improving and growth-promoting compound feed containing insect powder for raw fish
Costa et al. Studies on feeding peanut meal as a protein source for broiler chickens
Sabry‐Neto et al. Effects of soy protein ratio, lipid content and minimum level of krill meal in plant‐based diets over the growth and digestibility of the white shrimp, Litopenaeus vannamei
CN105876279A (en) Prawn feed with low fish meal content
CN103478414A (en) Feed rich in conjugated linoleic acid and preparation method of feed
Wang et al. Evaluation of the partial replacement of high-protein feedstuff with fermented soybean meal in broiler diets
CN103583462B (en) Cherry valley meat duckbreeding method
CN103549163B (en) Cherry Valley meat duck medium-stage feed
Akhavan-Salamat et al. The effects of Saccharomyces cerevisiae on performance and nutrients digestibility in broilers fed with diet containing different levels of phosphorous
CN104522326A (en) Formula of feed for milking sows and preparing method of the feed
Yamamoto et al. Growth and physiological effects of replacing fishmeal with dry-extruded seafood processing waste blended with plant protein feedstuffs in diets for red drum (Sciaenops ocellatus L.)
CN102228141B (en) Fattening pig feed without bean pulp and calcium hydrophosphate
Fan et al. Evaluation of four novel protein sources as alternatives to soybean meal for two specifications of cage-farmed grass carp (Ctenopharyngodon idellus) deeds: Effect on growth performance, flesh quality, and expressions of muscle-related genes
CN103931956B (en) Composition and the application thereof of pig build in a kind of raising
CN105685520A (en) Overfeeding-free formula feed composition for ducks to be made into roast ducks and application of overfeeding-free formula feed composition
Metwally et al. Effects of supplementing broiler diets with CreAMINO® on broiler performance, carcass traits and the expression of muscle growth related genes.
CN104336380A (en) Nutritive feed for meat ducks
CN110200162A (en) A kind of groove feed for pigling adjusting intestinal epithelial cell and intestinal growth
Varley et al. Effect of phytase concentration in a low phosphorus weaner pig diet and its subsequent effect on bone development in the finished pig

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20190906