CN110192950A - A kind of bearing hydrocolloid dressing and preparation method thereof - Google Patents
A kind of bearing hydrocolloid dressing and preparation method thereof Download PDFInfo
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- CN110192950A CN110192950A CN201910577536.2A CN201910577536A CN110192950A CN 110192950 A CN110192950 A CN 110192950A CN 201910577536 A CN201910577536 A CN 201910577536A CN 110192950 A CN110192950 A CN 110192950A
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- hydrocolloid
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- separation net
- line
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- 239000000416 hydrocolloid Substances 0.000 title claims abstract description 145
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 238000000926 separation method Methods 0.000 claims abstract description 53
- 229920000297 Rayon Polymers 0.000 claims abstract description 34
- 229920001971 elastomer Polymers 0.000 claims description 44
- 239000000463 material Substances 0.000 claims description 37
- 239000000806 elastomer Substances 0.000 claims description 22
- 239000005060 rubber Substances 0.000 claims description 22
- 239000002480 mineral oil Substances 0.000 claims description 17
- 235000010446 mineral oil Nutrition 0.000 claims description 17
- 239000004677 Nylon Substances 0.000 claims description 16
- 229920001778 nylon Polymers 0.000 claims description 16
- 239000004902 Softening Agent Substances 0.000 claims description 15
- 239000002250 absorbent Substances 0.000 claims description 11
- 238000002156 mixing Methods 0.000 claims description 11
- 239000001814 pectin Substances 0.000 claims description 11
- 229920001277 pectin Polymers 0.000 claims description 11
- 235000010987 pectin Nutrition 0.000 claims description 11
- 239000011347 resin Substances 0.000 claims description 11
- 229920005989 resin Polymers 0.000 claims description 11
- 150000003505 terpenes Chemical class 0.000 claims description 11
- 235000007586 terpenes Nutrition 0.000 claims description 11
- 108010010803 Gelatin Proteins 0.000 claims description 8
- 230000002745 absorbent Effects 0.000 claims description 8
- 239000008273 gelatin Substances 0.000 claims description 8
- 229920000159 gelatin Polymers 0.000 claims description 8
- 235000019322 gelatine Nutrition 0.000 claims description 8
- 235000011852 gelatine desserts Nutrition 0.000 claims description 8
- 239000003292 glue Substances 0.000 claims description 8
- 239000011248 coating agent Substances 0.000 claims description 7
- 238000000576 coating method Methods 0.000 claims description 7
- 229920000642 polymer Polymers 0.000 claims description 7
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 6
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 6
- 229920001935 styrene-ethylene-butadiene-styrene Polymers 0.000 claims description 5
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 4
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 4
- 238000010521 absorption reaction Methods 0.000 claims description 3
- 229920002521 macromolecule Polymers 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 239000011148 porous material Substances 0.000 claims description 3
- 239000008601 oleoresin Substances 0.000 claims 1
- 239000004575 stone Substances 0.000 claims 1
- 230000010354 integration Effects 0.000 abstract description 13
- 230000006378 damage Effects 0.000 abstract description 8
- 238000001035 drying Methods 0.000 abstract 1
- 238000002474 experimental method Methods 0.000 description 5
- 239000004744 fabric Substances 0.000 description 5
- 238000000748 compression moulding Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 2
- 238000012803 optimization experiment Methods 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 238000004088 simulation Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- AQLLBJAXUCIJSR-UHFFFAOYSA-N OC(=O)C[Na] Chemical compound OC(=O)C[Na] AQLLBJAXUCIJSR-UHFFFAOYSA-N 0.000 description 1
- 239000011358 absorbing material Substances 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000009514 concussion Effects 0.000 description 1
- 238000001804 debridement Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000037311 normal skin Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- KJFMBFZCATUALV-UHFFFAOYSA-N phenolphthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2C(=O)O1 KJFMBFZCATUALV-UHFFFAOYSA-N 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0203—Adhesive bandages or dressings with fluid retention members
- A61F13/0213—Adhesive bandages or dressings with fluid retention members the fluid retention member being a layer of hydrocolloid, gel forming material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
- A61F13/0289—Apparatus or processes for manufacturing adhesive dressings or bandages manufacturing of adhesive dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/24—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00655—Plasters adhesive
- A61F2013/00676—Plasters adhesive hydrogel
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Manufacturing & Machinery (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials For Medical Uses (AREA)
- Adhesives Or Adhesive Processes (AREA)
Abstract
The invention discloses a kind of bearing hydrocolloid dressing and preparation method thereof, dressing includes: backing film, coated on the hydrocolloid glue-line on backing film, is suppressed in the separation net on hydrocolloid glue-line, the release paper being covered on separation net and hydrocolloid glue-line；The present invention cooperates the formula of hydrocolloid blob of viscose to improve the degree of integration of hydrocolloid glue-line again by the way that separation net is arranged, and the setting of separation net can prevent hydrocolloid glue-line to be adhered with the drying surface of a wound, damage of the reduction to the surface of a wound.
Description
Technical field
The present invention relates to field of medical materials, especially a kind of bearing hydrocolloid dressing and preparation method thereof.
Background technique
Bearing hydrocolloid dressing is the dressing that flexible polymeric hydrogel and synthetic rubber and goo are mixed and processed.
Bearing hydrocolloid dressing has the characteristics that absorb wound exudate, after absorbing sepage, closed wet environment can be formed in wound circumference,
It can promote the formation of capillary proliferation and granulation tissue, to accelerate the healing of the surface of a wound；In addition, there are also debridements for bearing hydrocolloid dressing
Function.Degree of integration is an important indicator of bearing hydrocolloid dressing, and the bad bearing hydrocolloid dressing of degree of integration will appear when in use
Glue-line rupture, it is discrete, so that hydrocolloid glue line material may be made to remain on the surface of a wound.Bearing hydrocolloid dressing in some cases
Certain damage may can be caused to the surface of a wound when opening dressing with surface of a wound generation being adhered centainly；Market needs one kind to mention
The bearing hydrocolloid dressing of the degree of integration of high bearing hydrocolloid dressing, the present invention solve such problems.
Summary of the invention
To solve the deficiencies in the prior art, the purpose of the present invention is to provide a kind of bearing hydrocolloid dressing and preparation method thereof,
The formula of hydrocolloid blob of viscose is cooperated to improve the degree of integration of hydrocolloid glue-line again by the way that separation net is arranged, the setting of separation net can prevent
Hydrocolloid glue-line is adhered with the dry surface of a wound, reduces the damage to the surface of a wound.
In order to achieve the above objectives, the present invention adopts the following technical scheme that:
A kind of bearing hydrocolloid dressing, comprising: backing film is suppressed coated on the hydrocolloid glue-line on backing film in hydrocolloid glue
Separation net on layer, the release paper being covered on separation net and hydrocolloid glue-line.
A kind of bearing hydrocolloid dressing above-mentioned, separation net are suppressed in the center of hydrocolloid glue-line.
Distance among a kind of bearing hydrocolloid dressing above-mentioned, the edge of separation net and the edge of hydrocolloid glue-line is more than or equal to
1cm.A kind of bearing hydrocolloid dressing above-mentioned, separation net include: nylon separation net, PET separation net, PES separation net.
A kind of bearing hydrocolloid dressing above-mentioned, the pore diameter range of separation net are 100-500 μm, and thickness range is 50-300 μm,
Percent opening range is 40-80%.
A kind of bearing hydrocolloid dressing above-mentioned, hydrocolloid glue-line composition have: central boss extends central boss periphery
The thin body portion in four sides.
A kind of bearing hydrocolloid dressing above-mentioned, the thickness range of central boss are 0.5-3mm, the thin body portion in four sides with a thickness of
0.1-0.4mm。
A kind of bearing hydrocolloid dressing above-mentioned, the formula of hydrocolloid glue-line include: rubber elastomer 50-55 according to mass fraction
Part, 5-10 parts of tackifier, 12-30 parts of polymer absorbent material, 12-20 parts of softening agent；Rubber elastomer includes: SIS, SEBS,
SBS, EVA；Tackifier include: terpene resin, Petropols；Softening agent is mineral oil, and polymer absorbent material includes: carboxymethyl
Sodium cellulosate, pectin, gelatin.
A kind of bearing hydrocolloid dressing above-mentioned, 53 parts of rubber elastomer SIS, 10 parts of tackifier Petropols, polymeric absorbent
18 parts of material pectin, 19 parts of softening agent mineral oil.
A kind of preparation method of bearing hydrocolloid dressing,
Prepare material according to formula, includes: 50-55 parts of rubber elastomer according to mass fraction formula, 5-10 parts of tackifier,
12-30 parts of polymer absorbent material, 12-20 parts of softening agent, rubber elastomer includes: SIS, SEBS, SBS, EVA；Tackifier packet
It includes: terpene resin, Petropols；Softening agent is mineral oil, and polymer absorbent material includes: sodium carboxymethylcellulose, and pectin is bright
Glue；
Place the material in mixer, in 200 DEG C of mixing 60min, hydrocolloid blob of viscose is obtained；
Hydrocolloid blob of viscose is put into tabletting forming machine, by hydrocolloid coating on PU film, obtains hydrocolloid coiled material；
Hydrocolloid coiled material, separation net, release paper are packed on applicator, separation net is pasted on water under the control of machine
On colloid glue-line, then in covering release paper protection above, obtain bearing hydrocolloid dressing.
The invention has the beneficial effects that:
The present invention cooperates the formula raising of hydrocolloid blob of viscose to improve hydrocolloid glue-line degree of integration again by the way that separation net is arranged,
It thus avoids there is a phenomenon where glue-line breakage, be swollen rupture；
Hydrocolloid glue-line can be prevented by the setting of separation net and dries being adhered for the surface of a wound, thus can be reduced and removed glue
To the damage of the surface of a wound when body dressing.
Detailed description of the invention
Fig. 1 is a kind of sectional view of embodiment of the invention；
Fig. 2 is a kind of top view of embodiment of the invention.
The meaning of appended drawing reference in figure:
1 backing film, 2 hydrocolloid glue-lines, 201 central boss, the thin body portion in 202 4 sides, 3 separation nets, 4 release papers.
Specific embodiment
Specific introduce is made to the present invention below in conjunction with the drawings and specific embodiments.
As shown in Figure 1, a kind of bearing hydrocolloid dressing, comprising: backing film 1, coated on the hydrocolloid glue-line 2 on backing film 1, pressure
The separation net 3 being formed on hydrocolloid glue-line 2, the release paper 4 being covered on separation net 3 and hydrocolloid glue-line 2.As a kind of excellent
Choosing, release paper 4 are Ge Laxin paper.
Separation net 3 is suppressed in the center of hydrocolloid glue-line 2；Such as Fig. 2, separation net 3 is located at 2 centre bit of hydrocolloid glue-line
It sets, 3 position of separation net is contacted with the surface of a wound, and the glue-line and normal skin tissue around without net bond.
Distance among the edge of separation net 3 and the edge of hydrocolloid glue-line 2 is more than or equal to 1cm.
3 material of separation net can be nylon, PET, PES；As a preference, separation net 3 is nylon separation net 3；Isolation
The pore diameter range of net 3 is 100-500 μm, and thickness range is 50-300 μm, and percent opening range is 40-80%；As a preference,
The aperture of separation net 3 is 260 μm, with a thickness of 150 μm, percent opening 50%.
The composition of hydrocolloid glue-line 2 has: central boss 201 extends the thin body portion in four sides on 201 periphery of central boss
202；According to clinical practice demand, the thickness of central boss 201 is in 0.5-3mm, the thickness 0.1- in the thin body portion 202 in four sides
0.4mm；Common specification is as follows:
Example 1: 201 area of central boss is 8cm × 8cm, the thin 202 area 10cm × 10cm of body portion in four sides；
Example 2: 201 area 5cm × 5cm of central boss, the thin 202 area 6cm × 6cm of body portion in four sides；
Example 3: 201 area 10cm × 10cm of central boss, the thin 202 area 12cm × 12cm of body portion in four sides.
The formula of hydrocolloid glue-line 2 includes: 50-55 parts of rubber elastomer according to mass fraction, and 5-10 parts of tackifier, high score
Sub- water-absorbent material 12-30 parts, 12-20 parts of softening agent；Rubber elastomer includes: SIS, SEBS, SBS, EVA；Tackifier include: terpene
Olefine resin, Petropols；Softening agent is mineral oil, and polymer absorbent material includes: sodium carboxymethylcellulose, pectin, gelatin.
A kind of preparation method of bearing hydrocolloid dressing,
Prepare material according to formula；
Place the material in mixer, in 200 DEG C of mixing 60min, hydrocolloid blob of viscose is obtained；
Hydrocolloid blob of viscose is put into tabletting forming machine, by hydrocolloid coating on PU film, obtains hydrocolloid coiled material；
Hydrocolloid coiled material, separation net, release paper 4 are packed on applicator, are pasted on separation net under the control of machine
On hydrocolloid glue-line 2, then in covering release paper 4 protection above, obtain bearing hydrocolloid dressing.
Experiment one can be improved degree of integration with the formula of following experimental verification hydrocolloid blob of viscose cooperation separation net, reduce
Peel strength reduces and tears damage；
Embodiment 1:
By 50 parts of rubber elastomer SIS, 8 parts of terpene resins, 30 parts of sodium carboxymethylcelluloses and 12 parts of mineral oil, it is placed in
In the mixer of 20r/min, in 200 DEG C of mixing 60min, hydrocolloid blob of viscose is obtained.Hydrocolloid blob of viscose is put into chase form
Hydrocolloid coating is obtained the thin hydrocolloid coiled material of center thickness surrounding on PU film at 180 DEG C by the tabletting forming machine of tool, in
The heart thickness 1.2mm, edge thickness 0.2mm.By hydrocolloid coiled material, PES net, (aperture is 300 μm, with a thickness of 100 μm, aperture respectively
49%) rate is, on the loading applicator of release paper 4, PES net is pasted on 2 center of hydrocolloid glue-line under the control of machine, above
Release paper 4 is covered to protect.
The bearing hydrocolloid dressing that center is thick, surrounding is thin, centre contact the surface of a wound, and the relatively thin position of surrounding is pasted on surface of a wound week
Intact skin is enclosed, to fix dressing.According to clinical practice demand, for the thickness of central boss 201 in 0.5-3mm, four sides are thin
The thickness 0.1-0.4mm in body portion 202；Common specification is as follows:
Example 1: 201 area of central boss is 8cm × 8cm, the thin bulk area 10cm × 10cm in four sides；
Example 2: central boss 201 area 5cm × 5cm, the thin bulk area 6cm × 6cm in four sides；
Example 3: central boss 201 area 10cm × 10cm, the thin bulk area 12cm × 12cm in four sides；
Embodiment 2:
By SEBS55 parts of rubber elastomer, 5 parts of terpene resin, 25 parts of gelatin, 15 parts of mineral oil are placed in the close of 20r/min
In mill, in 200 DEG C of mixing 60min, hydrocolloid blob of viscose is obtained.Hydrocolloid blob of viscose is put into the compression molding with pure flat mold
Hydrocolloid coating is obtained the hydrocolloid coiled material with a thickness of 0.2mm on PU film at 80 DEG C by machine.Respectively by hydrocolloid coiled material,
PET net (aperture is 190 μm, with a thickness of 60 μm, percent opening 70%), release paper 4 are packed on applicator, under the control of machine
PET net is pasted on 2 center of hydrocolloid glue-line, is no less than 1 centimetre apart from edge, release paper 4 is covered above and protects.
Embodiment 3:
By SEBS55 parts of rubber elastomer, 5 parts of terpene resin, 25 parts of gelatin, 15 parts of mineral oil are placed in the close of 20r/min
In mill, in 200 DEG C of mixing 60min, hydrocolloid blob of viscose is obtained.Hydrocolloid blob of viscose is put into the compression molding with pure flat mold
Hydrocolloid coating is obtained the hydrocolloid coiled material with a thickness of 0.5mm on PU film at 80 DEG C by machine.Respectively by hydrocolloid coiled material,
Nylon wire (aperture is 190 μm, with a thickness of 100 μm, percent opening 57%), release paper 4 are packed on applicator, in the control of machine
It is lower that nylon wire is pasted on 2 center of hydrocolloid glue-line, it is no less than 1 centimetre apart from edge, release paper 4 is covered above and protects.
Embodiment 4:
By SBS50 parts of rubber elastomer, 10 parts of Petropols, 20 parts of pectin, 20 parts of mineral oil.It is placed in the close of 20r/min
In mill, in 200 DEG C of mixing 60min, hydrocolloid blob of viscose is obtained.Hydrocolloid blob of viscose is put into the compression molding with pure flat mold
Hydrocolloid coating is obtained the hydrocolloid coiled material with a thickness of 1.0mm on PU film at 80 DEG C by machine.Respectively by hydrocolloid coiled material,
Nylon wire (aperture is 260 μm, with a thickness of 150 μm, percent opening 50%), release paper 4 are packed on applicator, in the control of machine
It is lower that nylon wire is pasted on 2 center of hydrocolloid glue-line, it is no less than 1 centimetre apart from edge, release paper 4 is covered above and protects.
1, detection compares glue-line degree of integration, peel strength and holds viscosity after dressing is made.2, simulation uses the damage to skin
Evil.The degree of integration of the bearing hydrocolloid dressing of separation net 3 test product as a comparison is not added.
Experimentation:
Degree of integration test: taking size is the bearing hydrocolloid dressing of 5cm × 5cm, peels release paper 4 off, and it is raw to be soaked in 200ml
It manages in salt water, shakes 24 hours, test its concussion front and back mass change.
Peel strength and viscosity is held referring to " the 4th part of YY/T1293.4-2016 contact Wound dressing: bearing hydrocolloid dressing "
Test.
Simulation uses test: sample being pasted on the intact skin of normal personnel and is tested, is removed after 24 hours.With by
Examination person's test position skin color, skin pain, test position residue glue situation are Appreciation gist when removing.
Experimental result:
Interpretation of result: can generally increase degree of integration using the hydrocolloid blob of viscose cooperation separation net 3 of formula of the invention,
Peel strength by the way that the bearing hydrocolloid dressing of separation net 3 is not added known to sample and the result of contrast sample, which is significantly greater than to have added, is isolated
The bearing hydrocolloid dressing of net 3, the bearing hydrocolloid dressing degree of integration that separation net 3 is in addition not added are poor.
The use of separation net 3, which can reduce the damage to the surface of a wound and reduce hydrocolloid, remains on the surface of a wound due to swelling
On.
Experiment two, hydrocolloid blob of viscose optimization experiment:
Embodiment 1: by 50 parts of rubber elastomer SIS, 8 parts of terpene resins, 30 parts of sodium carboxymethylcelluloses and 12 parts of mineral
Oil is placed in the mixer of 20r/min, in 200 DEG C of mixing 60min, obtains hydrocolloid blob of viscose 1.
Embodiment 2: by SEBS55 parts of rubber elastomer, 5 parts of terpene resin, 25 parts of gelatin, 15 parts of mineral oil are placed in 20r/
In the mixer of min, in 200 DEG C of mixing 60min, hydrocolloid blob of viscose 2 is obtained.
Embodiment 3: by SEBS55 parts of rubber elastomer, 5 parts of terpene resin, 25 parts of gelatin, 15 parts of mineral oil are placed in 20r/
In the mixer of min, in 200 DEG C of mixing 60min, hydrocolloid blob of viscose 3 is obtained.
Embodiment 4: by SIS53 parts of rubber elastomer, 10 parts of tackifier Petropols, macromolecule absorption material pectin 18
Part, it 19 parts of softening agent mineral oil, is placed in the mixer of 20r/min, in 200 DEG C of mixing 60min, obtains hydrocolloid blob of viscose 4.
Above-mentioned blob of viscose is put into tabletting forming machine, it is tabletted under the same conditions and coated on PU film, be made 10 ×
The hydrocolloid film of 10cm size, referring to " the 4th part of YY/T1293.4-2016 contact Wound dressing: bearing hydrocolloid dressing " into
Row test.
| Liquid inhales penetration for 24 hours | Hold stickiness | Peel strength | PH value | |
| Blob of viscose 1 | 3.4g | < 2.5mm | 2.2N | 5.3 |
| Blob of viscose 2 | 4.7g | < 2.5mm | 4.5N | 5.4 |
| Blob of viscose 3 | 4.1g | < 2.5mm | 3.7N | 4.8 |
| Blob of viscose 4 | 5.2g | < 2.5mm | 3.4N | 5.7 |
Interpretation of result: 4 liquid of blob of viscose suction penetration is best, and peel strength is moderate, and pH value is best, excellent in comprehensive performance
In other samples, therefore select the formula of blob of viscose 4 for optimal selection, i.e., by SIS53 parts of rubber elastomer, tackifier Petropols
10 parts, 18 parts of macromolecule absorption material pectin, 19 parts of softening agent mineral oil.
Experiment three, separation net optimization experiment；
Using hydrocolloid film obtained by hydrocolloid blob of viscose optimization formula as substrate, the association of separation net 3 and hydrocolloid is tested
The same sex.
Embodiment 1: by pressure roller by aperture be 260 μm, 150 μm of thickness, percent opening be 50% nylon wire and hydrocolloid
Bonding is integrated.
Embodiment 2: by aperture being 260 μm by pressure roller, 150 μm of thickness, the PET net and hydrocolloid that percent opening is 50% are viscous
It is integrated.
Embodiment 3: by aperture being 260 μm by pressure roller, 150 μm of thickness, the PES net and hydrocolloid that percent opening is 50% are viscous
It is integrated.
Embodiment 4: by aperture being 100 μm by pressure roller, 80 μm of thickness, the nylon wire and hydrocolloid that percent opening is 53% are viscous
It is integrated.
Embodiment 5: by pressure roller by aperture be 500 μm, 280 μm of thickness, percent opening be 43% nylon wire and hydrocolloid
Bonding is integrated.
Interpretation of result: through embodiment 1-3 it is recognised that under conditions of same apertures, percent opening, thickness, nylon every
The pliability of off-network 3 is best.Comparative example 1,4, the nylon wire of 5 three kind of different size are it is found that the too small then screen cloth of mesh and glue
The binding force of layer is poor, screen cloth defective tightness in conjunction with glue-line.If selecting large aperture, thicker screen cloth, it may appear that when bending
The phenomenon that screen cloth and glue-line disengage.To sum up, preferred 3 material of separation net is nylon wire, and screen cloth parameter is 260 μm, 150 μ of thickness
M, percent opening 50%.
Comprehensive Experiment two and experiment three are it is found that according to SIS53 parts of rubber elastomer, and 10 parts of tackifier Petropols, high score
18 parts of sub- absorbing material pectin, 19 parts of the softening agent mineral oil hydrocolloid blob of viscoses prepared and parameter are 260 μm, 150 μm of thickness, are opened
The nylon wire that porosity is 50% has optimal synergistic effect.
The present invention cooperates the formula raising of hydrocolloid blob of viscose to propose 2 degree of integration of hydrocolloid glue-line again by the way that nylon wire is arranged
Height, thus avoid there is a phenomenon where glue-line breakage, be swollen rupture；Hydrocolloid glue-line 2 can be prevented by the setting of separation net 3 and is done
The dry surface of a wound is adhered, and thus can reduce the damage when removing bearing hydrocolloid dressing to the surface of a wound.
The basic principles, main features and advantages of the invention have been shown and described above.The technical staff of the industry should
Understand, the above embodiments do not limit the invention in any form, all obtained by the way of equivalent substitution or equivalent transformation
Technical solution is fallen within the scope of protection of the present invention.
Claims (10)
1. a kind of bearing hydrocolloid dressing characterized by comprising backing film, coated on the hydrocolloid glue-line on the backing film, pressure
The separation net being formed on the hydrocolloid glue-line, the release paper being covered on the separation net and hydrocolloid glue-line.
2. a kind of bearing hydrocolloid dressing according to claim 1, which is characterized in that the separation net compacting is in the hydrocolloid
The center of glue-line.
3. a kind of bearing hydrocolloid dressing according to claim 2, which is characterized in that the edge and hydrocolloid glue of the separation net
Distance among the edge of layer is more than or equal to 1cm.
4. a kind of bearing hydrocolloid dressing according to claim 1, which is characterized in that the separation net includes: nylon separation net,
PET separation net, PES separation net.
5. a kind of bearing hydrocolloid dressing according to claim 1, which is characterized in that the pore diameter range of the separation net is 100-
500 μm, thickness range is 50-300 μm, and percent opening range is 40-80%.
6. a kind of bearing hydrocolloid dressing according to claim 1, which is characterized in that the hydrocolloid glue-line composition has: center
Lug boss extends the thin body portion in four sides on the central boss periphery.
7. a kind of bearing hydrocolloid dressing according to claim 6, which is characterized in that the thickness range of the central boss is
0.5-3mm, the thin body portion in four sides with a thickness of 0.1-0.4mm.
8. a kind of bearing hydrocolloid dressing according to claim 1, which is characterized in that the formula of hydrocolloid glue-line is according to mass parts
Number includes: 50-55 parts of rubber elastomer, 5-10 parts of tackifier, 12-30 parts of polymer absorbent material, 12-20 parts of softening agent；Rubber
Glue elastomer includes: SIS, SEBS, SBS, EVA；Tackifier include: terpene resin, Petropols；Softening agent is mineral oil, high
Molecule water-absorbent material includes: sodium carboxymethylcellulose, pectin, gelatin.
9. a kind of bearing hydrocolloid dressing according to claim 8, which is characterized in that SIS53 parts of rubber elastomer, tackifier stone
10 parts of oleoresin, 18 parts of macromolecule absorption material pectin, 19 parts of softening agent mineral oil.
10. a kind of preparation method of bearing hydrocolloid dressing, which is characterized in that
Prepare material according to formula, includes: 50-55 parts of rubber elastomer according to mass fraction formula, 5-10 parts of tackifier, high score
Sub- water-absorbent material 12-30 parts, 12-20 parts of softening agent, rubber elastomer includes: SIS, SEBS, SBS, EVA；Tackifier include: terpene
Olefine resin, Petropols；Softening agent is mineral oil, and polymer absorbent material includes: sodium carboxymethylcellulose, pectin, gelatin；
Place the material in mixer, in 200 DEG C of mixing 60min, hydrocolloid blob of viscose is obtained；
Hydrocolloid blob of viscose is put into tabletting forming machine, by hydrocolloid coating on PU film, obtains hydrocolloid coiled material；
Hydrocolloid coiled material, separation net, release paper are packed on applicator, separation net is pasted on hydrocolloid under the control of machine
On glue-line, then in covering release paper protection above, obtain bearing hydrocolloid dressing.
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| CN201910577536.2A CN110192950A (en) | 2019-06-28 | 2019-06-28 | A kind of bearing hydrocolloid dressing and preparation method thereof |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101559236A (en) * | 2009-02-12 | 2009-10-21 | 泰州市三易医疗科技有限公司 | Silver-bearing hydrocolloid dressing and preparation method |
| CN101862470A (en) * | 2010-05-28 | 2010-10-20 | 武汉锐尔生物科技有限公司 | Bacteriostatic hydrocolloid dressing and preparation method thereof |
| CN207323620U (en) * | 2016-07-27 | 2018-05-08 | 北京健康广济生物技术有限公司 | A kind of novel hydrogels adhesive bandage |
| CN207575472U (en) * | 2017-05-25 | 2018-07-06 | 河南汇博医疗股份有限公司 | A kind of antibacterial anti hemorrhagic combine dressing |
| CN108904135A (en) * | 2018-09-15 | 2018-11-30 | 深圳市浓华生物电子科技有限公司 | A kind of moisture film is cured the wound patch |
| CN210843806U (en) * | 2019-06-28 | 2020-06-26 | 振德医疗用品股份有限公司 | Hydrocolloid dressing |
-
2019
- 2019-06-28 CN CN201910577536.2A patent/CN110192950A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101559236A (en) * | 2009-02-12 | 2009-10-21 | 泰州市三易医疗科技有限公司 | Silver-bearing hydrocolloid dressing and preparation method |
| CN101862470A (en) * | 2010-05-28 | 2010-10-20 | 武汉锐尔生物科技有限公司 | Bacteriostatic hydrocolloid dressing and preparation method thereof |
| CN207323620U (en) * | 2016-07-27 | 2018-05-08 | 北京健康广济生物技术有限公司 | A kind of novel hydrogels adhesive bandage |
| CN207575472U (en) * | 2017-05-25 | 2018-07-06 | 河南汇博医疗股份有限公司 | A kind of antibacterial anti hemorrhagic combine dressing |
| CN108904135A (en) * | 2018-09-15 | 2018-11-30 | 深圳市浓华生物电子科技有限公司 | A kind of moisture film is cured the wound patch |
| CN210843806U (en) * | 2019-06-28 | 2020-06-26 | 振德医疗用品股份有限公司 | Hydrocolloid dressing |
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