CN110186734A - Muchine for preparing membrane liquid base thin-layer cell smear - Google Patents
Muchine for preparing membrane liquid base thin-layer cell smear Download PDFInfo
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- CN110186734A CN110186734A CN201910553460.XA CN201910553460A CN110186734A CN 110186734 A CN110186734 A CN 110186734A CN 201910553460 A CN201910553460 A CN 201910553460A CN 110186734 A CN110186734 A CN 110186734A
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- 239000007788 liquid Substances 0.000 title claims abstract description 191
- 239000012528 membrane Substances 0.000 title claims abstract description 50
- 239000011521 glass Substances 0.000 claims abstract description 20
- 238000003780 insertion Methods 0.000 claims abstract description 5
- 230000037431 insertion Effects 0.000 claims abstract description 5
- 230000007306 turnover Effects 0.000 claims description 29
- 230000005540 biological transmission Effects 0.000 claims description 10
- 239000007787 solid Substances 0.000 claims description 2
- 239000012530 fluid Substances 0.000 abstract description 16
- 238000010586 diagram Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- External Artificial Organs (AREA)
Abstract
The present invention relates to a kind of muchine for preparing membrane liquid base thin-layer cell smear, including rack and the filter membrane cup being arranged on the rack, filter membrane cup includes the liquid flowing tube and liquid storing tube mutually to socket-connect, the conical pipe being equipped in liquid flowing tube in insertion container, the liquid storage film abutted with the bottom of conical pipe is equipped in liquid storing tube, rack, which is equipped with, takes the fixed device of liquid, is additionally provided with liquid storage driving device in rack；Sliding is equipped with the glass slide that can extend between liquid flowing tube and liquid storing tube in the horizontal direction in rack；The getter device for communicating and generating negative pressure with liquid storing tube when liquid flowing tube is socketed with liquid storing tube is additionally provided in rack.Since filter membrane cup is disposable, after use finishes, it disposes, in this way it is possible to prevente effectively from there is pollution condition when drawing different cell base fluids, simultaneously because filter membrane cup is disposable, it is directly thrown away using finishing, does not need to clear up pelleter repeatedly, operated also very convenient.
Description
Technical field
The present invention relates to the technical fields of pelleter, more particularly, to a kind of muchine for preparing membrane liquid base thin-layer cell smear.
Background technique
An existing muchine for preparing membrane liquid base thin-layer cell smear negative pressure pump multi-purpose greatly filters multiple filter membrane cups simultaneously, will go out
It is uneven now to take out pressure, similarly filters the time, film cup content tends to have Liquid Residue, leads to cross contamination.
Notification number provides a kind of muchine for preparing membrane liquid base thin-layer cell smear for the utility model of CN 208026527U, passes through
Multiple negative pressure pumps are set and filter membrane cup and solenoid valve parallel connection are guaranteed into drawing liquid effect to obtain the suction for stablizing big flow.
When in use, it needs that the cell base fluid in filter membrane cup is sucked out by liquid sucking tube head, then passes through light inductance again
Cell should be transferred on glass slide with pressure sensitive, complete the output of cell, in operation, liquid sucking tube head can repeat to draw thin
Born of the same parents' base fluid, if cleaned not in time to liquid sucking tube head, just will appear when needing to transfer different cells
It is inaccurate to lead to testing result, but often cleans to liquid sucking tube head for the mixing of different sample cells, operates again very
It is inconvenient.
Summary of the invention
The object of the present invention is to provide a kind of muchine for preparing membrane liquid base thin-layer cell smear, frequent clean is not only needed, but also can be with
The phenomenon that avoiding the occurrence of different mixing with cells guarantees testing result accuracy.
Foregoing invention purpose of the invention has the technical scheme that a kind of membrane liquid base thin-layer cell
Pelleter, including rack and the filter membrane cup being arranged on the rack, the filter membrane cup include the liquid flowing tube that mutually socket-connects with
And liquid storing tube, the interior conical pipe being equipped in insertion container of the liquid flowing tube, interior be equipped with of the liquid storing tube are supported with the bottom of conical pipe
The liquid storage film connect, the rack are equipped with for placing the putting hole of liquid flowing tube and for liquid flowing tube to be fixed in putting hole
Take the fixed device of liquid, be additionally provided in the rack for liquid storing tube to be fixed on liquid flowing tube coaxial position and along vertical
The liquid storage driving device of direction sliding；Sliding to be equipped in the horizontal direction in the rack can extend between liquid flowing tube and liquid storing tube
Glass slide；The air-breathing dress for communicating and generating negative pressure with liquid storing tube when liquid flowing tube is socketed with liquid storing tube is additionally provided in the rack
It sets.
By using above-mentioned technical proposal, when work, the fixed device of liquid is taken to fix filter membrane cup, getter device is filtering
Negative pressure is generated in film cup, in the presence of having negative pressure in filter membrane cup, suction the base fluid in container can be sucked out, with cell
Base fluid by being stopped after conical pipe by liquid storage film, kept in onto liquid storage film by cell, when getter device is by the base fluid in container
After quantitative absorption, liquid storage driving device drives liquid storing tube and liquid flowing tube separation, provides space for the immigration of glass slide, carries glass
Piece slides in the horizontal direction to be arranged between liquid storing tube and liquid flowing tube, the cell on liquid storage film can be transferred to glass slide at this time
On, filter membrane cup be it is disposable, after practical finish, dispose, in this way it is possible to prevente effectively from absorption not
With cell base fluid when there is pollution condition, simultaneously because filter membrane cup be it is disposable, directly thrown away using finishing, no
It needs to clear up pelleter repeatedly, operate also very convenient.
The present invention is further arranged to: described to take the fixed device of liquid include sliding the be arranged on the rack in the horizontal direction
One clamping plate, the first clamping plate is two and is symmetricly set on putting hole two sides, and it is opposite that the rack is equipped with driving first clamping plate
Or the first actuator slided opposite to each other.
By using above-mentioned technical proposal, when needing that liquid flowing tube is fixed, first clamping plate protrudes into putting hole
It is interior, it is abutted with the outer wall of liquid flowing tube, liquid flowing tube is clamped, realize fixation of the liquid flowing tube in putting hole, the first actuator ten
It is divided to the sliding for facilitating and realizing two first clamping plates.
The present invention is further arranged to: the liquid storage driving device includes sliding the bottom being arranged on the rack along the vertical direction
Plate, the floor level are arranged and are equipped with the through hole for placing liquid storing tube, and it is symmetrical to be located at through hole two sides on the bottom plate
Equipped with second clamping plate, the bottom plate, which is equipped with, drives two second clamping plates opposite or the second actuator of back movement；It is described
Rack is equipped with the third actuator that driving bottom plate slides along the vertical direction.
By using above-mentioned technical proposal, when needing that liquid storing tube is fixed, second clamping plate protrudes into through hole
It is interior, it is abutted with the outer wall of liquid storing tube, liquid storing tube is clamped, realize fixation of the liquid storing tube in through hole.In order to facilitate realization
The sliding of two second clamping plates is equipped with two second clamping plates of driving the second actuator adjacent to each other on the rack.Third driving
Part can be slided with bottom plate, after absorption finishes, liquid storing tube and liquid flowing tube can be separated, and due to liquid storing tube and be taken at this time
Liquid pipe is fixed on top plate and bottom plate respectively, therefore, when bottom plate is far from top plate, liquid storing tube can be realized and take
The separation of liquid pipe.
The present invention is further arranged to: the first actuator includes being parallel to first clamping plate glide direction and being rotatably arranged on machine
The first double threaded screw on frame, two first clamping plates are threadedly coupled with the first double threaded screw both ends respectively, in the rack
First motor equipped with driving the first double threaded screw rotation.
By using above-mentioned technical proposal, when work, first motor is opened, first motor drives the first double threaded screw to rotate forward
Perhaps the adjacent to each other or separate of two first clamping plates can be realized in reversion, and has self-locking function due to being threadedly coupled,
Therefore it does not need additionally to increase locking structure, when first motor stalling, still can guarantee that two first clamping plates are in solid
Determine state, simplifies structure, it is easy to control.
The present invention is further arranged to: the second actuator includes being parallel to second clamping plate glide direction and being rotatably arranged on bottom
The second double threaded screw on plate, two second clamping plates are threadedly coupled with the second double threaded screw both ends respectively, on the bottom plate
The second motor equipped with driving the second double threaded screw rotation.
By using above-mentioned technical proposal, when work, the second motor is opened, second the second double threaded screw of motor driven rotates forward
Perhaps the adjacent to each other or separate of two second clamping plates can be realized in reversion,
The present invention is further arranged to: third actuator includes being rotatably arranged on third screw rod in rack along the vertical direction, described
Bottom plate is connect with third screw flight.
By using above-mentioned technical proposal, third screw rod is rotated, the driving and fixation of bottom plate, structure letter can be realized
It is single, it is easy to operate.
The present invention is further arranged to: the first motor is arranged along the sliding of the first double threaded screw length direction in rack
On, the third screw rod is equipped with driven wheel of differential far from one end of bottom plate, is rotatably connected in the rack and driven wheel of differential
The drive bevel gear of engagement, the drive bevel gear are set on the output shaft of first motor, and the rack is equipped with driving the
One motor slippage and the switching device of fixation, after output shaft sliding respectively with the transmission connection of the first double threaded screw or actively
Bevel Gear Transmission connection.
By using above-mentioned technical proposal, under the driving of switching device, after the sliding of the output shaft of first motor respectively with
The transmission connection of first double threaded screw or drive bevel gear transmission connection, it is only necessary to which the position for converting first motor can be realized the
The driving of one double threaded screw or drive bevel gear only needs a first motor in this way, can be realized simultaneously the first double end spiral shell
The driving of bar and third screw rod, compact-sized, work efficiency is high.
The present invention is further arranged to: the switching device includes the electromagnet being fixed on the rack, the electromagnetism
Iron is arranged in first motor glide direction, is equipped between the electromagnet and first motor and drives first after electromagnet power-off
The reset spring of reset motor.
By using above-mentioned technical proposal, when electromagnet is powered, electromagnet can adsorb first motor, at this time the first electricity
Machine is in the state being driven with drive bevel gear；After electromagnet power-off, reset spring can drive first motor towards first
Double threaded screw sliding, connecting key is pushed into keyway, realizes the transmission connection of first motor and the first double threaded screw.
The present invention is further arranged to: the getter device includes the turnover panel with bottom plate rotation connection, is set on the bottom plate
There is the third motor being bonded after driving turnover panel rotation with liquid storing tube bottom surface, leads on the turnover panel through equipped with what is communicated with liquid storing tube
Stomata, the venthole are connected with air pump.
By using above-mentioned technical proposal, open air pump, air pump can air-breathing, generate suction in filter membrane cup, will be thin
Born of the same parents' base fluid goes out from container interior suction, and the shaft of the output shaft of third motor and turnover panel connects, through being equipped with and liquid storing tube on turnover panel
The venthole communicated, venthole are connected with air pump.
The present invention is further arranged to: the side that the bottom plate turnover panel is contacted with liquid storing tube is equipped with Gask-O-Seal.
By using above-mentioned technical proposal, gasket can be improved the leakproofness between turnover panel and liquid storing tube, turnover panel with deposit
The side of liquid pipe contact is equipped with Gask-O-Seal, and venthole is located in Gask-O-Seal, when turnover panel turns to horizontal position,
Gask-O-Seal can be abutted with liquid storing tube bottom surface, and then improve the leakproofness between turnover panel and liquid storing tube, guarantee pumping effect.
In conclusion advantageous effects of the invention are as follows:
1. not needing to clean pelleter repeatedly, safeguard and easy to operate；
2. structure is simple, reliable operation.
Detailed description of the invention
Fig. 1 is overall structure diagram of the invention.
Fig. 2 is filter membrane cup sectional arrangement drawing of the invention.
Fig. 3 is of the invention to take the fixed device of liquid and liquid storage driving device structure schematic diagram.
Fig. 4 is setter plate assembling schematic diagram of the invention.
Fig. 5 is first clamping plate and second clamping plate scheme of installation of the invention.
Fig. 6 is vertical direction cross-sectional view in Fig. 3.
Fig. 7 is bottom base plate structural schematic diagram.
In figure, 1, rack；2, top plate；21, putting hole；22, first clamping plate；23, the first double threaded screw；231, axle sleeve；24,
First motor；241, connecting key；242, frictional disk；25, electromagnet；26, reset spring；27, drive bevel gear；28, guide rod；
3, bottom plate；31, through hole；32, second clamping plate；33, the second double threaded screw；34, the second motor；35, turnover panel；351, ring packing
Pad；352, venthole；4, container；5, filter membrane cup；51, liquid flowing tube；511, conical pipe；52, liquid storing tube；521, liquid storage film；6,
Third screw rod；61, driven wheel of differential；7, holding groove；8, setter plate；81, open slot；9, glass slide；10, third motor.
Specific embodiment
Below in conjunction with attached drawing, invention is further described in detail.
Referring to Fig.1 and Fig. 2, be a kind of muchine for preparing membrane liquid base thin-layer cell smear disclosed by the invention, including rack 1 and
Filter membrane cup 5 in rack 1 is set, and filter membrane cup 5 includes the liquid flowing tube 51 and liquid storing tube 52 mutually to socket-connect, liquid flowing tube 51
Be set in outside liquid storing tube 52, the conical pipe 511 being equipped in liquid flowing tube 51 in insertion container 4, the bigger diameter end of conical pipe 511 with take
The inner wall of liquid pipe 51 is fixed, and the top of liquid storing tube 52 is equipped with liquid storage film 521, and liquid storage film 521 has certain air permeability, works as liquid storing tube
When in 52 insertion liquid flowing tubes 51, liquid storage film 521 is abutted with the bottom of conical pipe 511.Be additionally provided in rack 1 liquid flowing tube 51 with
Liquid storing tube 52 communicates with liquid storing tube 52 and generates the getter device of negative pressure when being socketed, getter device can produce suction, work as filtering
In the presence of having negative pressure in film cup 5, suction the base fluid in container 4 can be sucked out, the base fluid with cell by conical pipe 511 it
Stopped afterwards by liquid storage film 521, cell is kept in onto liquid storage film 521, filter membrane cup 5 be it is disposable, finished when practical
Later, it disposes, in this way it is possible to prevente effectively from there is pollution condition when drawing different cell base fluids, simultaneously because mistake
Filter membrane cup 5 is disposably, directly to be thrown away using finishing, do not need to clear up pelleter repeatedly, is operated also very
It is convenient.
Referring to Fig. 3 and Fig. 5, rack 1 includes top plate 2, and top plate 2 is horizontally disposed, offers on top plate 2 and takes for placing
The putting hole 21 of liquid pipe 51, the diameter of putting hole 21 are greater than the outer diameter of liquid flowing tube 51, are additionally provided on top plate 2 and consolidate liquid flowing tube 51
It is scheduled on top plate 2 and takes the fixed device of liquid, rack 1 is equipped with for liquid storing tube 52 to be fixed on and 51 coaxial position of liquid flowing tube
Liquid storage driving device, liquid storage driving device can also drive liquid storing tube 52 to slide along its axis direction, when getter device is by container 4
After interior base fluid is quantitatively drawn, liquid storage driving device drives liquid storing tube 52 and liquid flowing tube 51 to separate, and is the immigration of glass slide 9
Space is provided, glass slide 9 slides in the horizontal direction to be arranged between liquid storing tube 52 and liquid flowing tube 51.
Referring to Fig. 4 and Fig. 5, when starting operation, liquid storing tube 52 connects together with liquid flowing tube 51, at this time glass slide 9
In outside putting hole 21, after cell base fluid is transferred on liquid storage film 521, liquid storage driving device driving liquid storing tube 52 is moved down,
Liquid storing tube 52 is separated with liquid flowing tube 51, at this time slides into glass slide 9 between liquid storing tube 52 and liquid flowing tube 51, and then sliding is deposited again
Liquid pipe 52, driving liquid storage film 521 are contacted with glass slide 9, complete the transfer of cell.In order to facilitate positioning glass slide 9, in rack 1
Upper sliding is equipped with setter plate 8, and setter plate 8 is equipped with the open slot 81 matched with 9 size of glass slide, in use, by glass slide 9
It is placed in open slot 81, then setter plate 8 is pushed between bottom plate 3 and top plate 2, glass slide 9 can be located at liquid storing tube at this time
Right above 52.
Referring to Fig. 5 and Fig. 6, taking the fixed device of liquid includes sliding the first clamping plate being arranged on top plate 2 in the horizontal direction
22, first clamping plate 22 is two and is symmetricly set on the two sides of putting hole 21, is equipped on top plate 2 and slides for first clamping plate 22
First sliding groove, first clamping plate 22 are embedded on top plate 2, and when needing that liquid flowing tube 51 is fixed, first clamping plate 22 is stretched
Enter in putting hole 21, abutted with the outer wall of liquid flowing tube 51, liquid flowing tube 51 is clamped, realizes liquid flowing tube 51 in putting hole 21
It is fixed, the sliding of two first clamping plates 22 is realized for convenience, and it is adjacent to each other that two first clamping plates 22 of driving are equipped in rack 1
The first actuator.
Referring to Fig. 5 and Fig. 6, in the present embodiment, the first actuator includes being parallel to the glide direction of first clamping plate 22 to set
The first double threaded screw 23 set, the both ends thread rotary orientation of the first double threaded screw 23 is on the contrary, the first double threaded screw 23 is rotatably arranged on
On top plate 2, two first clamping plates 22 are threadedly coupled with the both ends of the first double threaded screw 23 respectively, and driving is additionally provided on top plate 2
The first motor 24 of first double threaded screw 23 rotation, the output shaft of first motor 24 and the first double threaded screw 23 are coaxially disposed, work
When making, first motor 24 is opened, first motor 24 drives the first double threaded screw 23 to rotate forward or invert, can be realized two first
Clamping plate 22 it is adjacent to each other or separate, and due to be threadedly coupled have self-locking function, do not need additionally increase locking
Structure still can guarantee that two first clamping plates 22 are to simplify structure, control in stationary state when first motor 24 stalls
System is convenient.
Referring to Fig. 5 and Fig. 6, liquid storage driving device includes sliding the bottom plate 3 being arranged in rack 1, bottom along the vertical direction
Plate 3 is arranged in parallel with top plate 2, and fixed there are two guide rod 28 along the vertical direction in the bottom of top plate 2, the sliding setting of bottom plate 3 exists
On guide rod 28, the through hole 31 for placing liquid storing tube 52 is equipped on bottom plate 3, the outer diameter of through hole 31 is greater than liquid flowing tube 51
And liquid storing tube 52, it is equipped with second clamping plate 32 positioned at the two sides of through hole 31 on bottom plate 3, two second clamping plates 32 are symmetrical arranged
In the two sides of through hole 31, the second sliding slot slid for second clamping plate 32 is equipped on bottom plate 3, second clamping plate 32 is embedded in top plate
On 2, when needing that liquid storing tube 52 is fixed, second clamping plate 32 is protruded into through hole 31, the outer wall with liquid storing tube 52
It abuts, liquid storing tube 52 is clamped, realize fixation of the liquid storing tube 52 in through hole 31.In order to facilitate two second clamping plates of realization
32 sliding is equipped with two second clamping plates 32 of driving the second actuator adjacent to each other in rack 1.Further, since drawing
It after finishing, needs to separate liquid storing tube 52 and liquid flowing tube 51, therefore is additionally provided with driving bottom plate 3 along vertical side on top plate 2
To the third actuator of sliding, third actuator can drive bottom plate 3 to slide, since liquid storing tube 52 and liquid flowing tube 51 are respectively
It is fixed on top plate 2 and bottom plate 3, therefore, when bottom plate 3 is far from top plate 2, liquid storing tube 52 and liquid flowing tube can be realized
51 separation.
Referring to Fig. 5 and Fig. 6, the second actuator includes the second double end for being parallel to the glide direction setting of second clamping plate 32
Screw rod 33, the both ends thread rotary orientation of the second double threaded screw 33 is on the contrary, the second double threaded screw 33 is rotatably arranged on bottom plate 3, and two
Second clamping plate 32 is threadedly coupled with the both ends of the second double threaded screw 33 respectively, and the second double threaded screw of driving is additionally provided on top plate 2
Second motors 34 of 33 rotations, the output shaft of the second motor 34 and the second double threaded screw 33 are coaxially disposed, when work, unlatching second
Motor 34, the second motor 34 drive the second double threaded screw 33 to rotate forward or invert, the mutual of two second clamping plates 32 can be realized
It is close or separate,
Referring to Fig. 5 and Fig. 6, third actuator includes the third screw rod 6 being rotatably arranged on top plate 2 along the vertical direction, third
The top of screw rod 6 and bottom plate 3 are rotatablely connected, and the bottom of third screw rod 6 is threadedly coupled with bottom plate 3, rotate third screw rod 6
Realize the driving and fixation of bottom plate 3, structure is simple, easy to operate.
Referring to Fig. 5 and Fig. 6, for convenience of the driving for realizing third screw rod 6, first motor 24 is along the first double threaded screw 23
Length direction sliding is arranged in rack 1, and the top of third screw rod 6 connects driven wheel of differential 61 after top plate 2, from mantle tooth
Wheel 61 is fixed at the top of third screw rod 6, and the drive bevel gear 27 engaged with driven wheel of differential 61 is rotatably connected on top plate 2,
The convex block for installing drive bevel gear 27 is fixed on top plate 2, drive bevel gear 27 is coaxially set with the first double threaded screw 23
It sets, drive bevel gear 27 is set on the output shaft of first motor 24, respectively with first after the sliding of the output shaft of first motor 24
The transmission connection of double threaded screw 23 or drive bevel gear 27 are sequentially connected, it is only necessary to which the position for converting first motor 24 can be realized
The driving of first double threaded screw 23 or drive bevel gear 27 only needs a first motor 24 in this way, can be realized simultaneously the
The driving of one double threaded screw 23 and third screw rod 6, compact-sized, work efficiency is high.
Referring to Fig. 5 and Fig. 6, it is equipped with and first motor 24 in the first double threaded screw 23 close to one end of first motor 24
The axle sleeve 231 of output shaft cooperation, is equipped with keyway along 231 length direction of axle sleeve in axle sleeve 231, in the output shaft of first motor 24
It is equipped with the connecting key 241 that cooperate with keyway close to one end of the first double threaded screw 23, after the sliding of first motor 24, output shaft can be with
Axle sleeve 231 is protruded into or removes, when output shaft protrudes into axle sleeve 231, connecting key 241 and keyway cooperate, and at this time first
The rotation of the first double threaded screw 23 can be driven in motor 24.Frictional disk 242 is further fixed on the output shaft of first motor 24, when
When one motor 24 and the first double threaded screw 23 are sequentially connected, frictional disk 242 is not contacted with the side of drive bevel gear 27；When
Connecting key 241 be located at axle sleeve 231 it is outer when, frictional disk 242 is abutted with 27 side of drive bevel gear, passes through frictional disk at this time
Frictional force between 242 and drive bevel gear 27 can drive frictional disk 242 to rotate when first motor 24 rotates, only
It needs to slide first motor 24, respectively driving for the first double threaded screw 23 and the second double threaded screw 33 can be realized.
Referring to Fig. 5 and Fig. 6, position of the first motor 24 on top plate 2 is adjusted for convenience, is equipped with and drives on top plate 2
The dynamic sliding of first motor 24 and fixed switching device, when work, switching device drives first motor 24 under two kinds of positions
Switching, both positions respectively correspond first motor 24 and the transmission connection of the first double threaded screw 23 and are driven with drive bevel gear 27
Connection.Switching device includes the electromagnet 25 being fixed on top plate 2, and electromagnet 25 is arranged in 24 glide direction of first motor
On, the reset spring that driving first motor 24 resets after the power-off of electromagnet 25 is equipped between electromagnet 25 and first motor 24
26, when electromagnet 25 is powered, electromagnet 25 can adsorb first motor 24, and first motor 24 is in and drive bevel gear at this time
The state of 27 transmissions；After electromagnet 25 powers off, reset spring 26 can drive first motor 24 towards the first double threaded screw 23
Sliding, even if what original state connecting key 241 and keyway were not in alignment with, after motor rotation, the position of connecting key 241 and keyway
Also it can be adjusted, after connecting key 241 is aligned with keyway, connecting key 241 can be pushed into keyway by reset spring 26, real
The transmission connection of existing first motor 24 and the first double threaded screw 23.
Referring to Fig. 6 and Fig. 7, in order to guarantee the stability of getter device, getter device includes being rotatablely connected with bottom plate 3
Turnover panel 35, for the rotational plane of turnover panel 35 perpendicular to bottom plate 3, the underface of through hole 31 is arranged in turnover panel 35, and bottom plate 3, which is equipped with, to be driven
The third motor 10 that dynamic turnover panel 35 is bonded after rotating with 52 bottom surface of liquid storing tube, the output shaft of third motor 10 and the shaft of turnover panel 35
Connection, through the venthole 352 communicated with liquid storing tube 52 is equipped on turnover panel 35, venthole 352 is connected with air pump and (does not show in figure
Out), tracheae is equipped between air pump and turnover panel 35, tracheae one end is connect with venthole 352, the air entry phase of the other end and air pump
Even, when needing to draw cell base fluid, third motor 10 drives turnover panel 35 to rotate, and turnover panel 35 is abutted with 52 bottom surface of liquid storing tube,
Open air pump, air pump can air-breathing, generate suction in filter membrane cup 5, cell base fluid be sucked out out of container 4.
Referring to Fig. 6, in order to improve the leakproofness between turnover panel 35 and liquid storing tube 52, the side that turnover panel 35 is contacted with liquid storing tube 52
Face is equipped with Gask-O-Seal 351, and venthole 352 is located in Gask-O-Seal 351, when turnover panel 35 turns to horizontal position,
Gask-O-Seal 351 can be abutted with 52 bottom surface of liquid storing tube, and then improve the leakproofness between turnover panel 35 and liquid storing tube 52, be guaranteed
It is evacuated effect.
In addition, the filter membrane cup 5 after use is separated with container 4 for convenience, is located in rack 1 referring to Fig. 5
Holding groove 7 is equipped with below through hole 31, the inclined bottom surface of holding groove 7 is arranged, and after cell transfer finishes, glass slide 9 is removed,
Bottom plate 3 slides again up at this time, and liquid flowing tube 51 and liquid storing tube 52 are connected together, and then extracts container 4 manually, due to
The clamping of first clamping plate 22 and second clamping plate 32, filter membrane cup 5 still can stay in rack 1, finally open first clamping plate 22,
Second clamping plate 32 and turnover panel 35, filter membrane cup 5 can be fallen into holding groove 7, exported out of holding groove 7, be can be completed at this time
Tableting operation.
The implementation principle of the present embodiment are as follows: before film-making, the conical pipe 511 on filter membrane cup 5 is inserted into container 4 first
It is interior, then upward by 5 bottom surface of filter membrane cup, filter membrane cup 5 is inserted into placement hole, first motor 24 drives the first double threaded screw 23
Rotation, the second motor 34 drive the rotation of the second double threaded screw 33, and two first clamping plates 22 and two second clamping plates 32 are leaned on mutually
Closely, filter membrane cup 5 is fixedly clamped, the position abutted with 52 bottom surface of liquid storing tube is turned to end blocking 35, air pump is opened, in mistake
Suction is generated in filter membrane cup 5, cell base fluid is sucked out out of container 4 and in the liquid storage film 521 that is temporarily stored on liquid storing tube 52；
Subsequent electromagnet 25 is opened, and driving first motor 24 is slided, and first motor 24 drives drive bevel gear 27 to rotate, and then is driven
Dynamic third screw rod 6 rotates, and 3 slide downward of bottom plate separates liquid storing tube 52 and liquid flowing tube 51, and glass slide 9 is slid into bottom at this time
Between plate 3 and top plate 2, the cell on liquid storage film 521 is transferred on glass slide 9, film-making can be completed by 3 upward sliding of bottom plate.
The embodiment of present embodiment is presently preferred embodiments of the present invention, not limits protection of the invention according to this
Range, therefore: the equivalence changes that all structures under this invention, shape, principle are done, should all be covered by protection scope of the present invention it
It is interior.
Claims (10)
1. a kind of muchine for preparing membrane liquid base thin-layer cell smear, the filter membrane cup (5) including rack (1) and setting on rack (1),
It is characterized by: the filter membrane cup (5) includes the liquid flowing tube (51) and liquid storing tube (52) mutually to socket-connect, the liquid flowing tube
(51) conical pipe (511) being equipped in insertion container (4), the interior bottom being equipped with conical pipe (511) of the liquid storing tube (52)
The liquid storage film (521) of abutting, the rack (1) are equipped with for placing the putting hole (21) of liquid flowing tube (51) and for that will take
Liquid pipe (51) is fixed in putting hole (21) and takes the fixed device of liquid, is additionally provided on the rack (1) for by liquid storing tube (52)
The liquid storage driving device for being fixed on the position coaxial with liquid flowing tube (51) and sliding along the vertical direction；Edge on the rack (1)
Horizontal direction sliding is equipped with the glass slide (9) that can extend between liquid flowing tube (51) and liquid storing tube (52)；On the rack (1) also
Equipped with being communicated when liquid flowing tube (51) and liquid storing tube (52) are socketed with liquid storing tube (52) and generate the getter device of negative pressure.
2. muchine for preparing membrane liquid base thin-layer cell smear according to claim 1, it is characterised in that: described to take the fixed device packet of liquid
The first clamping plate (22) that sliding is arranged on rack (1) in the horizontal direction is included, the first clamping plate (22) is two and is symmetrical arranged
In putting hole (21) two sides, the rack (1) is equipped with the first driving that driving first clamping plate (22) is opposite or slides opposite to each other
Part.
3. muchine for preparing membrane liquid base thin-layer cell smear according to claim 2, it is characterised in that: the liquid storage driving device packet
The bottom plate (3) that sliding is arranged on rack (1) along the vertical direction is included, the bottom plate (3) is horizontally disposed and deposits equipped with being used to place
The through hole (31) of liquid pipe (52) is located at through hole (31) two sides on the bottom plate (3) and is symmetrically arranged with second clamping plate (32), described
Bottom plate (3), which is equipped with, drives two second clamping plates (32) opposite or the second actuator of back movement；It is set on the rack (1)
The third actuator for thering is driving bottom plate (3) to slide along the vertical direction.
4. muchine for preparing membrane liquid base thin-layer cell smear according to claim 3, it is characterised in that: the first actuator includes parallel
In first clamping plate (22) glide direction and the first double threaded screw (23) for being rotatably arranged on rack (1), two first folders
Plate (22) is threadedly coupled with the first double threaded screw (23) both ends respectively, and the rack (1) is equipped with the first double threaded screw of driving
(23) first motor (24) rotated.
5. muchine for preparing membrane liquid base thin-layer cell smear according to claim 3 or 4, it is characterised in that: the second actuator includes
The second double threaded screw (33) for being parallel to second clamping plate (32) glide direction and being rotatably arranged on bottom plate (3), two described
Second splint (32) is threadedly coupled with the second double threaded screw (33) both ends respectively, and the bottom plate (3) is equipped with the second double end spiral shell of driving
The second motor (34) of bar (33) rotation.
6. muchine for preparing membrane liquid base thin-layer cell smear according to claim 4, it is characterised in that: third actuator includes along perpendicular
Histogram is threadedly coupled to third screw rod (6) on rack (1), the bottom plate (3) is rotatably arranged on third screw rod (6).
7. muchine for preparing membrane liquid base thin-layer cell smear according to claim 6, it is characterised in that: first motor (24) edge
The sliding of first double threaded screw (23) length direction is arranged on rack (1), the one end of the third screw rod (6) far from bottom plate (3)
Equipped with driven wheel of differential (61), the drive bevel gear engaged with driven wheel of differential (61) is rotatably connected on the rack (1)
(27), the drive bevel gear (27) is set on the output shaft of first motor (24), and the rack (1) is equipped with driving first
Motor (24) sliding and fixed switching device are sequentially connected with the first double threaded screw (23) respectively after the output shaft sliding
Or drive bevel gear (27) transmission connection.
8. muchine for preparing membrane liquid base thin-layer cell smear according to claim 7, it is characterised in that: the switching device includes solid
The fixed electromagnet (25) being arranged on rack (1), the electromagnet (25) is arranged in first motor (24) glide direction, described
The reset that driving first motor (24) resets after electromagnet (25) power-off is equipped between electromagnet (25) and first motor (24)
Spring (26).
9. muchine for preparing membrane liquid base thin-layer cell smear according to claim 1, it is characterised in that: the getter device include with
The turnover panel (35) of bottom plate (3) rotation connection, the bottom plate (3) are equipped with after driving turnover panel (35) rotates and liquid storing tube (52) bottom surface
The third motor (10) of fitting is described logical through being equipped with the venthole (352) communicated with liquid storing tube (52) on the turnover panel (35)
Stomata (352) is connected with air pump.
10. muchine for preparing membrane liquid base thin-layer cell smear according to claim 9, it is characterised in that: bottom plate (3) turnover panel
(35) side contacted with liquid storing tube (52) is equipped with Gask-O-Seal (351).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910553460.XA CN110186734A (en) | 2019-06-25 | 2019-06-25 | Muchine for preparing membrane liquid base thin-layer cell smear |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910553460.XA CN110186734A (en) | 2019-06-25 | 2019-06-25 | Muchine for preparing membrane liquid base thin-layer cell smear |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110186734A true CN110186734A (en) | 2019-08-30 |
Family
ID=67723139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910553460.XA Pending CN110186734A (en) | 2019-06-25 | 2019-06-25 | Muchine for preparing membrane liquid base thin-layer cell smear |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110186734A (en) |
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| CN111551417A (en) * | 2020-04-01 | 2020-08-18 | 郑州中普医疗器械有限公司 | Automatic film making device |
| CN111551756A (en) * | 2020-04-01 | 2020-08-18 | 郑州中普医疗器械有限公司 | Full-automatic film-making dyeing scanning system |
| CN114074053A (en) * | 2021-12-20 | 2022-02-22 | 合肥河钢新材料科技有限公司 | Double-coating machine set for zero-time switching coating |
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| CN114074053B (en) * | 2021-12-20 | 2022-10-28 | 合肥河钢新材料科技有限公司 | Double-coating machine set for zero-time switching coating |
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