CN110180043A - A kind of sequence ballon pump formula left ventricular assist device - Google Patents

A kind of sequence ballon pump formula left ventricular assist device Download PDF

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Publication number
CN110180043A
CN110180043A CN201910603889.5A CN201910603889A CN110180043A CN 110180043 A CN110180043 A CN 110180043A CN 201910603889 A CN201910603889 A CN 201910603889A CN 110180043 A CN110180043 A CN 110180043A
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CN
China
Prior art keywords
sacculus
sequence
left ventricular
ventricular assist
assist device
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910603889.5A
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Chinese (zh)
Inventor
王钊
张乐峰
赵晴
王梓慕
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Beijing Sheng Biotechnology LLC
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Beijing Sheng Biotechnology LLC
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Publication date
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Priority to CN201910603889.5A priority Critical patent/CN110180043A/en
Publication of CN110180043A publication Critical patent/CN110180043A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/122Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/148Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/122Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/165Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart
    • A61M60/17Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20Type thereof
    • A61M60/247Positive displacement blood pumps
    • A61M60/253Positive displacement blood pumps including a displacement member directly acting on the blood
    • A61M60/268Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/50Details relating to control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/04General characteristics of the apparatus implanted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/04Heartbeat characteristics, e.g. ECG, blood pressure modulation

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

The present invention provides a kind of sequence ballon pump formula left ventricular assist devices, including conduit, control equipment, electrocardiogram acquisition equipment, and A sacculus, B sacculus, C sacculus in conduit are set, each sacculus is correspondingly provided with a pump housing, described pump housing one end is connected to sacculus, the other end is connected to fluid source, and the pump housing all connects control equipment;The conduit both ends conducting, one end are blood inlet end, and the other end is bleeding end;The signal output end connection control equipment of the electrocardiogram acquisition equipment, for sending human body electrocardio data to control equipment;The control equipment controls the contraction or diastole of different sacculus by controlling the operation of the pump housing.Sequence ballon pump formula left ventricular assist device of the present invention is small in size, can pass through percutaneous puncture, be implanted directly into left ventricle through aorta petal mouth, wound is small, easy to operate, implantation speed is fast, Minimally Invasive Surgery, postoperative to be easy to rehabilitation, compare other Left ventricle assist products, and price is lower.

Description

A kind of sequence ballon pump formula left ventricular assist device
Technical field
The invention belongs to the field of medical instrument technology, more particularly, to a kind of sequence ballon pump formula left ventricular assist device.
Background technique
There are about 4,000,000 heart failure patients in the current 35-74 years old adult in China, for endstage cardiac insufficiency patient, The clinical effectiveness of heart transplant is substantially better than simple drug control heart failure.But there is a serious shortage of while facing row to heart donor The problem of different reaction, infection and other secondary diseases, and the development of left ventricular assist device, it is increasingly becoming the weight for solving serious heart failure Want approach.
Left ventricular assist device mainly has long-term auxiliary and short-term two kinds of auxiliary, develops main experienced three stages, and first Generation is bionical beating pump, by pneumatically or electrically driving diaphragm blood pump, generates pulsation blood flow, is commonly used for transition before transplanting and controls It treats, but the disadvantages of its volume is big, noise is big, appeal is high, blood pump inner membrance is tearable, valve is easy to aging, influences minimal invasive treatment's matter Amount, it sometimes appear that fatal complication.Second generation left ventricular assist device volume is smaller, and infection rate is lower, and noise is bright It is aobvious to reduce, quality of life can be obviously improved.Third generation left ventricular assist device further reduces the volume of artificial blood pump, adopts With magnetic levitation technology, there are preferable hemodynamic characteristics, bleeding and thrombus complication can be reduced.Left ventricle assist fills at present It sets, Heartware, the Maquet etc. assisted in short term such as assisted for a long time, it is constant current that international occupation rate is larger at home Pump, and pulsation type heart pump can apish heart, have the systole phase and diastole similar to heart, there are positive phases and negative The pressure phase improves the perfusion of the organs such as brain, heart and tail vein, promotes human metabolism.
Long-term left ventricular assist device needs are implanted into the patient, and are assisted human heart, and operation is complicated, and cost compared with It is high.For short-term left ventricular assist device, what use was most wide at present is ECMO (extracorporeal membrane oxygenation system), mostly in the ward ICU It uses, machinery equipment is very big, performs the operation more complex, costly, 2,000,000-300 ten thousand, patient's single makes general machine expense 70,000 or so are just needed with the expense of consumptive material.Equipment price is high, and operating difficulty Risks are to restrict left ventricular assist device application to push away greatly A wide major reason.In fact, postoperative 6 months survival rates reach 87% for long-term ventricular assist device, survive within 1 year Rate reaches 85%, and 2 years survival rates reach 79%, and survival rate reaches 73% within 3 years.And for some acute onset patients, the short-term heart Room auxiliary device is the unique sharp weapon for saving patient.
Summary of the invention
In view of this, the present invention is directed to propose a kind of sequence ballon pump formula left ventricular assist device, to solve an existing left side The problem that heart auxiliary device equipment volume is big, cost is high, complicated for operation.
In order to achieve the above objectives, the technical scheme of the present invention is realized as follows:
A kind of sequence ballon pump formula left ventricular assist device, including conduit, control equipment, electrocardiogram acquisition equipment, Yi Jishe A sacculus, B sacculus, C sacculus in conduit are set, each sacculus is correspondingly provided with a pump housing, and described pump housing one end is connected to ball Capsule, the other end are connected to fluid source, and the pump housing all connects control equipment;
The conduit both ends conducting, one end are blood inlet end, and the other end is bleeding end;
The signal output end connection control equipment of the electrocardiogram acquisition equipment, for sending human body electrocardio number to control equipment According to;
The control equipment controls the contraction or diastole of different sacculus by controlling the operation of the pump housing.
Further, A sacculus, B sacculus, C sacculus are all hollow resilient bladder.
Further, A sacculus, B sacculus, C sacculus are all blood compatibility material structural member.
Further, the pump housing is connected to sacculus by blood compatibility conduit.
Further, the electrocardiogram acquisition equipment is electrocardiogram acquisition patch, and the electrocardiogram acquisition patch is attached on human body.
Further, the blood inlet end of the conduit is pointed structures or blunt circle structure.
Further, the sacculus A is for simulating bicuspid valve, and sacculus B is for simulating left ventricle, and sacculus C is for simulating master Arterial valve.
Further, the fluid source is gas or liquid.
Compared with the existing technology, sequence ballon pump formula left ventricular assist device of the present invention has the advantage that
Sequence ballon pump formula left ventricular assist device of the present invention is small in size, can pass through percutaneous puncture, through aorta Valve mouth is implanted directly into left ventricle, and wound is small, easy to operate, and implantation speed is fast, and Minimally Invasive Surgery is postoperative to be easy to rehabilitation, compares it His Left ventricle assist product, price are lower.
Detailed description of the invention
The attached drawing for constituting a part of the invention is used to provide further understanding of the present invention, schematic reality of the invention It applies example and its explanation is used to explain the present invention, do not constitute improper limitations of the present invention.In the accompanying drawings:
Fig. 1 is sequence ballon pump formula left ventricular assist device theory structure schematic diagram described in the embodiment of the present invention;
Fig. 2 is simulation ventricular diastole schematic diagram described in the embodiment of the present invention;
Fig. 3 is simulation ventricular systole schematic diagram described in the embodiment of the present invention.
Description of symbols:
1, conduit;2, A sacculus;3, B sacculus;4, C sacculus;5, the pump housing;6, equipment is controlled;7, electrocardiogram acquisition equipment;8, it flows Body source.
Specific embodiment
It should be noted that in the absence of conflict, the feature in embodiment and embodiment in the present invention can phase Mutually combination.
In the description of the present invention, it is to be understood that, term " center ", " longitudinal direction ", " transverse direction ", "upper", "lower", The orientation or positional relationship of the instructions such as "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside" is It is based on the orientation or positional relationship shown in the drawings, is merely for convenience of description of the present invention and simplification of the description, rather than instruction or dark Show that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore should not be understood as pair Limitation of the invention.In addition, term " first ", " second " etc. are used for description purposes only, it is not understood to indicate or imply phase To importance or implicitly indicate the quantity of indicated technical characteristic.The feature for defining " first ", " second " etc. as a result, can To explicitly or implicitly include one or more of the features.In the description of the present invention, unless otherwise indicated, " multiple " It is meant that two or more.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected;It can To be mechanical connection, it is also possible to be electrically connected;It can be directly connected, can also can be indirectly connected through an intermediary Connection inside two elements.For the ordinary skill in the art, above-mentioned term can be understood by concrete condition Concrete meaning in the present invention.
The present invention will be described in detail below with reference to the accompanying drawings and embodiments.
As shown in Figure 1, a kind of sequence ballon pump formula left ventricular assist device, including conduit 1, control equipment 6, electrocardiogram acquisition Equipment 7, and the A sacculus 2, B sacculus 3, the C sacculus 4 that are arranged in conduit 1, each sacculus are correspondingly provided with a pump housing 5, institute 5 one end of pump housing connection sacculus is stated, the other end is connected to fluid source 8, and the pump housing 5 all connects control equipment 6;
1 both ends of the conduit conducting, one end are blood inlet end, and the other end is bleeding end;
The signal output end connection control equipment 6 of the electrocardiogram acquisition equipment 7, is used for control 6 sender body-centered of equipment Electric data;
The control equipment 6 controls the contraction or diastole of different sacculus by the control pump housing 5.
The control equipment 6 includes the master control borad for carrying STM32F103ZET6 processor, the PWM issued by master control borad Pulse signal controls the operation of the pump housing 5, and then realizes inflation and discharge of the fluid source 8 in sacculus, reaches control sacculus diastole Or contraction, simulate left heart work.
A sacculus 2, B sacculus 3, C sacculus 4 are all hollow resilient bladder.A sacculus 2, B sacculus 3, C sacculus 4 are all blood phase Capacitive material structure part.The pump housing 5 is connected to sacculus by blood compatibility conduit.A sacculus 2, B sacculus 3, C sacculus 4 are all logical Cross the pump housing 5 be internally filled with fluid source 8 realize diastole purpose, when being shunk, can by sacculus itself elasticity from Row is shunk, and can also be extracted fluid source 8 out by the pump housing 5 and be shunk, and can reach what simulation sacculus was shunk by diversified forms Purpose can achieve the purpose that control diastole or contraction speed in the course of work by controlling the speed of service of the pump housing 5.
The electrocardiogram acquisition equipment 7 is electrocardiogram acquisition patch, and the electrocardiogram acquisition patch is attached on human body.Control equipment 6 According to the human body electrocardio data that electrocardiogram acquisition patch acquires, each pump housing 5 is individually controlled, more scientific, intelligence.
The blood inlet end of the conduit 1 is pointed structures or blunt circle structure.Sequence ballon pump formula left ventricular assist device can By percutaneous puncture, it is implanted directly into left ventricle through aorta petal mouth, wound is small, and easy to operate, implantation speed is fast, Minimally Invasive Surgery, Postoperative to be easy to rehabilitation, compare other Left ventricle assist products, and price is lower.
Sacculus A is for simulating bicuspid valve, and for controlling the blood in inflow catheter 1, sacculus B simulates left ventricle, analog Left ventricular contraction and diastole, sacculus C simulated aorta valve, for controlling blood outflow conduit 1.As shown in Fig. 2, in ventricular diastole Phase, sacculus A and sacculus B deflate, and conduit 1 is opened into blood side, sacculus C inflation, 1 bleeding side of conduit closure, blood inflow catheter 1 Chamber.As shown in figure 3, sacculus A inflation, conduit 1 is closed into blood side in paradoxical expansion, meanwhile, sacculus C deflates, and sacculus B first fills Gas gradually squeezes out the blood in conduit 1 from into blood side to outlet side, flows into aorta.And then sacculus C is inflated, sacculus A It deflates with sacculus B, blood back flows back among conduit 1.The process repeatedly, i.e. acquisition pulsatile flow, complete its accessory heart Function.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (8)

1. a kind of sequence ballon pump formula left ventricular assist device, it is characterised in that: including conduit (1), control equipment (6), electrocardio It acquires equipment (7), and the A sacculus (2), B sacculus (3), the C sacculus (4) that are arranged in conduit (1), each sacculus correspondence is set There is a pump housing (5), the described pump housing (5) one end is connected to sacculus, and the other end is connected to fluid source (8), and the pump housing (5) all connects control Control equipment (6);
Conduit (1) the both ends conducting, one end are blood inlet end, and the other end is bleeding end;
Signal output end connection control equipment (6) of the electrocardiogram acquisition equipment (7), for sending human body to control equipment (6) Electrocardiogram (ECG) data;
Control equipment (6) controls the contraction or diastole of different sacculus by controlling the operation of the pump housing (5).
2. sequence ballon pump formula left ventricular assist device according to claim 1, it is characterised in that: A sacculus (2), B sacculus (3), C sacculus (4) is all hollow resilient bladder.
3. sequence ballon pump formula left ventricular assist device according to claim 1 or 2, it is characterised in that: A sacculus (2), B Sacculus (3), C sacculus (4) are all blood compatibility material structural member.
4. sequence ballon pump formula left ventricular assist device according to claim 1, it is characterised in that: the pump housing (5) is logical Cross blood compatibility conduit connection sacculus.
5. sequence ballon pump formula left ventricular assist device according to claim 1, it is characterised in that: the electrocardiogram acquisition is set Standby (7) are electrocardiogram acquisition patch, and the electrocardiogram acquisition patch is attached on human body.
6. sequence ballon pump formula left ventricular assist device according to claim 1, it is characterised in that: the conduit (1) Blood inlet end is pointed structures or blunt circle structure.
7. sequence ballon pump formula left ventricular assist device according to claim 1, it is characterised in that: the sacculus A is used for Bicuspid valve is simulated, sacculus B is used for simulated aorta valve for simulating left ventricle, sacculus C.
8. sequence ballon pump formula left ventricular assist device according to claim 1, it is characterised in that: the fluid source (8) For gas or liquid.
CN201910603889.5A 2019-07-05 2019-07-05 A kind of sequence ballon pump formula left ventricular assist device Pending CN110180043A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113018543A (en) * 2021-03-02 2021-06-25 江苏赛腾医疗科技有限公司 Diversion control system

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WO2003068292A1 (en) * 2002-02-11 2003-08-21 National University Of Singapore Physiologically compatible cardiac assist device and method
US20110218382A1 (en) * 2010-03-08 2011-09-08 Wilmo Orejola Auto-regulated R-Wave Synchronized Intraventricular Balloon Pump Heart Assist Device
CN105749407A (en) * 2016-04-20 2016-07-13 周广如 Balloon dilatation catheter for blood vessels or valves
CN105816926A (en) * 2016-05-05 2016-08-03 丁以群 Heart assistant device
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CN210812926U (en) * 2019-07-05 2020-06-23 北京安生生物技术有限责任公司 Sequential balloon counterpulsation type left heart auxiliary device

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CN1253837A (en) * 1999-12-21 2000-05-24 马惠生 Method for making assisted circulation of ventriculus cordis and its device
WO2003068292A1 (en) * 2002-02-11 2003-08-21 National University Of Singapore Physiologically compatible cardiac assist device and method
US20110218382A1 (en) * 2010-03-08 2011-09-08 Wilmo Orejola Auto-regulated R-Wave Synchronized Intraventricular Balloon Pump Heart Assist Device
CN105749407A (en) * 2016-04-20 2016-07-13 周广如 Balloon dilatation catheter for blood vessels or valves
CN105816926A (en) * 2016-05-05 2016-08-03 丁以群 Heart assistant device
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CN108310497A (en) * 2018-02-12 2018-07-24 安徽通灵仿生科技有限公司 Minimally invasive catheter type synchronizes heart-assist device and its application method
CN210812926U (en) * 2019-07-05 2020-06-23 北京安生生物技术有限责任公司 Sequential balloon counterpulsation type left heart auxiliary device

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113018543A (en) * 2021-03-02 2021-06-25 江苏赛腾医疗科技有限公司 Diversion control system
CN113018543B (en) * 2021-03-02 2021-10-08 江苏赛腾医疗科技有限公司 Diversion control system

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