CN109966575A - A kind of single saccule counterpulsation formula left ventricular assist device - Google Patents

A kind of single saccule counterpulsation formula left ventricular assist device Download PDF

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Publication number
CN109966575A
CN109966575A CN201910368492.2A CN201910368492A CN109966575A CN 109966575 A CN109966575 A CN 109966575A CN 201910368492 A CN201910368492 A CN 201910368492A CN 109966575 A CN109966575 A CN 109966575A
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CN
China
Prior art keywords
micropump
sacculus
left ventricular
counterpulsation
assist device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910368492.2A
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Chinese (zh)
Inventor
王钊
张乐峰
赵晴
王梓慕
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Beijing Sheng Biotechnology LLC
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Beijing Sheng Biotechnology LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Sheng Biotechnology LLC filed Critical Beijing Sheng Biotechnology LLC
Priority to CN201910368492.2A priority Critical patent/CN109966575A/en
Publication of CN109966575A publication Critical patent/CN109966575A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/122Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/148Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20Type thereof
    • A61M60/247Positive displacement blood pumps
    • A61M60/253Positive displacement blood pumps including a displacement member directly acting on the blood
    • A61M60/268Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/50Details relating to control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/04General characteristics of the apparatus implanted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/04Heartbeat characteristics, e.g. ECG, blood pressure modulation

Abstract

It include sacculus, conduit, micropump 1, micropump 2, control system, EGC sensor and fluid source the present invention provides a kind of single saccule counterpulsation formula left ventricular assist device;Sacculus is placed in left ventricle, sacculus connecting tube one end, and the conduit other end is connected to micropump 1 and micropump 2, and micropump 1 and micropump 2 are connected to fluid source.A kind of single saccule counterpulsation formula left ventricular assist device of the present invention, it is simple with implantation, the characteristics of patient's resume speed is fast and cost economic, it can quickly substitute the left ventricular function of patient, the perfusion for facilitating the organs functions such as improvement brain, heart and tail vein, it is horizontal to improve human metabolism.

Description

A kind of single saccule counterpulsation formula left ventricular assist device
Technical field
The invention belongs to medical instruments fields, more particularly, to a kind of single saccule counterpulsation formula left ventricular assist device.
Background technique
There are about 4,000,000 heart failure patients in the current 35-74 years old adult in China, for endstage cardiac insufficiency patient, The clinical effectiveness of heart transplant is substantially better than simple drug control heart failure.But there is a serious shortage of while facing row to heart donor The problem of different reaction, infection and other secondary diseases, and the development of left ventricular assist device, it is increasingly becoming the weight for solving serious heart failure Want approach.
The main experienced three stages of the development of left ventricular assist device, the first generation is bionical beating pump, by pneumatically or electrically Diaphragm blood pump is driven, pulsation blood flow is generated, is commonly used for transplanting preceding bridging therapy, but its volume is big, noise is big, appeal High, the disadvantages of blood pump inner membrance is tearable and valve is easy to aging, patients ' life quality is seriously affected, it sometimes appear that fatal is concurrent Disease.Second generation left ventricular assist device volume is smaller, and infection rate is lower, and noise is obviously reduced, and can significantly improve life Quality.Third generation left ventricular assist device further reduces the volume of artificial blood pump, using magnetic levitation technology, has preferable Hemodynamic characteristics can reduce bleeding and thrombus complication.But it is multiple to there is implantation in above-mentioned existing left ventricular assist device Problem miscellaneous, cost is high and patient recovery times are long.
Summary of the invention
In view of this, the present invention is directed to propose a kind of single saccule counterpulsation formula left ventricular assist device, has implantation simply, patient The characteristics of resume speed is fast and cost economic, can quickly substitute the left ventricular function of patient, help to improve brain, heart etc. It is horizontal to improve human metabolism for the perfusion of organ function and tail vein.
In order to achieve the above objectives, the technical scheme of the present invention is realized as follows:
A kind of single saccule counterpulsation formula left ventricular assist device, including sacculus, conduit, micropump 1, micropump 2, control system, EGC sensor and fluid source;Sacculus is placed in left ventricle, sacculus connecting tube one end, and the conduit other end is connected to micropump 1 And micropump 2, micropump 1 and micropump 2 are connected to fluid source.
Fluid is driven into sacculus by micropump 1 from fluid source, and micropump 2 returns fluid from sacculus to fluid source It is interior;EGC sensor and the signal receiving end of control system connect, and EGC sensor acquires the Human Physiology telecommunications of human epidermal Number;Control system controls micropump 1 and micropump 2 will be in fluid source according to the collected physiology signal of EGC sensor Fluid extraction or be driven into sacculus.
Further, 1 signal output end of pump of control system is connect with 1 signal input part of pump of micropump 1.
Further, 2 signal input part of pump of 2 signal output end of the pump connection micropump 2 of control system.
Further, fluid source is gaseous fluid source or liquid fluid source.
Further, sacculus is blood compatibility material sacculus, and conduit is blood compatibility material conduit.
Compared with the existing technology, a kind of single saccule counterpulsation formula left ventricular assist device of the present invention, has the advantage that
A kind of single saccule counterpulsation formula left ventricular assist device of the present invention has the advantages that first, this single saccule counterpulsation formula is left Heart auxiliary device can be implanted into through the apex of the heart, atrial septum, aorta petal or coronary sinus vein, have the characteristics that implantation is simple;The Two, this single saccule counterpulsation formula left ventricular assist device has no mechanical damage to blood;Third, this single saccule counterpulsation formula left ventricular assist device It is low using economic cost.
Detailed description of the invention
The attached drawing for constituting a part of the invention is used to provide further understanding of the present invention, schematic reality of the invention It applies example and its explanation is used to explain the present invention, do not constitute improper limitations of the present invention.
In the accompanying drawings:
Fig. 1 is a kind of single saccule counterpulsation formula left ventricular assist device schematic illustration of the present invention;
Fig. 2 is a kind of single saccule counterpulsation formula left ventricular assist device structural schematic diagram of the present invention;
Fig. 3 is a kind of single saccule counterpulsation formula left ventricular assist device explanatory diagram of the embodiment of the present invention.
Specific embodiment
It should be noted that in the absence of conflict, the feature in embodiment and embodiment in the present invention can phase Mutually combination.
In the description of the present invention, it is to be understood that, term " center ", " longitudinal direction ", " transverse direction ", "upper", "lower", The orientation or positional relationship of the instructions such as "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside" is It is based on the orientation or positional relationship shown in the drawings, is merely for convenience of description of the present invention and simplification of the description, rather than instruction or dark Show that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore should not be understood as pair Limitation of the invention.In addition, term " first ", " second " etc. are used for description purposes only, it is not understood to indicate or imply phase To importance or implicitly indicate the quantity of indicated technical characteristic.The feature for defining " first ", " second " etc. as a result, can To explicitly or implicitly include one or more of the features.In the description of the present invention, unless otherwise indicated, " multiple " It is meant that two or more.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected;It can To be mechanical connection, it is also possible to be electrically connected;It can be directly connected, can also can be indirectly connected through an intermediary Connection inside two elements.For the ordinary skill in the art, above-mentioned term can be understood by concrete condition Concrete meaning in the present invention.
The present invention will be described in detail below with reference to the accompanying drawings and embodiments.
As shown in Figs. 1-2, a kind of single saccule counterpulsation formula left ventricular assist device, including sacculus, conduit, micropump 1, micropump 2, control system, EGC sensor and fluid source;Sacculus is placed in left ventricle, sacculus connecting tube one end, the conduit other end It is connected to micropump 1 and micropump 2, micropump 1 and micropump 2 are connected to fluid source.
Fluid is driven into sacculus by micropump 1 from fluid source, and micropump 2 returns fluid from sacculus to fluid source It is interior;EGC sensor and the signal receiving end of control system connect, and EGC sensor acquires the Human Physiology telecommunications of human epidermal Number;Control system controls micropump 1 and micropump 2 will be in fluid source according to the collected physiology signal of EGC sensor Fluid extraction or be driven into sacculus.
As shown in Fig. 2, 1 signal output end of pump of control system is connect with 1 signal input part of pump of micropump 1.
As shown in Fig. 2, 2 signal input part of pump of 2 signal output end of the pump connection micropump 2 of control system.
As shown in Figure 1, fluid source is gaseous fluid source or liquid fluid source.
As shown in Figure 1, sacculus is blood compatibility material sacculus, conduit is blood compatibility material conduit.
The Human Physiology electric signal of EGC sensor acquisition human epidermal;Control system is collected according to EGC sensor Fluid in fluid source is extracted out or is driven into sacculus by physiology signal, control micropump.
Fluid in fluid source can be carbon dioxide gas or physiological saline etc..EGC sensor is placed directly against human body table At Pi Shang, such as hand pulse etc..
In the present embodiment, sacculus can be implanted to left ventricle through the apex of the heart, atrial septum, aorta petal or coronary sinus vein In, as shown in Figure 1, sacculus functions as left ventricle, for squeezing into human vas blood from left ventricle, guarantee blood Liquid stream is to whole body.EGC sensor is arranged on human epidermal, and at hand pulse, obtained electrocardiosignal is transferred to control system System, control system output a control signal to micropump 1 or micropump 2, realize the full or emptying of sacculus, to assist realizing left The function of ventricle.
In the present embodiment:
As shown in figure 3, processor module is STM32F103ZET6 processor.
As shown in figure 3, the ADC123_INx of the signal output end connection STM32F103ZET6 processor of EGC sensor is fixed Adopted pin.
As shown in figure 3, power module 3.3V output end be separately connected STM32F103ZET6 processor VDD pin and VDDA pin.
As shown in figure 3, the TIM2_CH2 of the PWM interface connection STM32F103ZET6 processor of micropump 1 defines pin.
As shown in figure 3, the TIM3_CH2 of the PWM interface connection STM32F103ZET6 processor of micropump 2 defines pin.
As shown in figure 3,1 import of micropump, by conduit communicated air bags, the outlet of micropump 2 passes through conduit communicated air bags.
As shown in figure 3, power module is YS-5D3312H type dual output power supply.
In the present embodiment, in ventricular diastole, STM32F103ZET6 processor receives EGC sensor and acquires signal, leads to It crosses TIM2_CH2 and defines pin transmission pwm control signal to micropump 1,1 import of micropump at this time sucks fluid in air bag, through going out Mouth is drained into fluid source, and air bag empties at this time, and blood flows into left ventricle;In paradoxical expansion, STM32F103ZET6 processor Pin, which is defined, by TIM3_CH2 sends pwm control signal to micropump 2,2 import of micropump at this time sucks fluid in fluid source, It is drained into air bag through outlet, keeps air bag full, the blood stream in left ventricle is entered in aorta, then flows to whole body everywhere. The above is merely preferred embodiments of the present invention, it is not intended to limit the invention, all within the spirits and principles of the present invention, Any modification, equivalent replacement, improvement and so on should all be included in the protection scope of the present invention.

Claims (5)

1. a kind of single saccule counterpulsation formula left ventricular assist device, it is characterised in that: including sacculus, conduit, micropump 1, micropump 2, Control system, EGC sensor and fluid source;The sacculus is placed in left ventricle, and the sacculus is connected to the tube at one end, The conduit other end is connected to the micropump 1 and the micropump 2, the micropump 1 and the micropump 2 are connected to the stream Body source;
Fluid is driven into the sacculus by the micropump 1 from the fluid source, and the micropump 2 is by fluid from the ball It is returned in capsule in the fluid source;The EGC sensor is connect with the signal receiving end of the control system, the electrocardio The Human Physiology electric signal of sensor acquisition human epidermal;The control system is according to the collected human body of the EGC sensor Physiological signal controls the micropump 1 and the micropump 2 for the fluid in the fluid source and extracts or be driven into the sacculus out It is interior.
2. a kind of single saccule counterpulsation formula left ventricular assist device according to claim 1, it is characterised in that: the control system 1 signal output end of pump connect with 1 signal input part of pump of the micropump 1.
3. a kind of single saccule counterpulsation formula left ventricular assist device according to claim 1, it is characterised in that: the control system 2 signal output end of pump connect 2 signal input part of pump of the micropump 2.
4. a kind of single saccule counterpulsation formula left ventricular assist device according to claim 1, it is characterised in that: the fluid source is Gaseous fluid source or liquid fluid source.
5. a kind of single saccule counterpulsation formula left ventricular assist device according to claim 1, it is characterised in that: the sacculus is blood Liquid phase capacitive material sacculus, the conduit are blood compatibility material conduit.
CN201910368492.2A 2019-05-05 2019-05-05 A kind of single saccule counterpulsation formula left ventricular assist device Pending CN109966575A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110559497A (en) * 2019-09-19 2019-12-13 厦门大学附属第一医院 heart auxiliary support balloon system, manufacturing method thereof and heart auxiliary device

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CN106668965A (en) * 2017-01-06 2017-05-17 张乐峰 Balloon counterpulsation driven mechanical auxiliary circulating device with valves
CN107158549A (en) * 2017-06-29 2017-09-15 吴强 For regulating and controlling left ventricle capacity to improve the servicing unit of Cardial pump function
CN109395185A (en) * 2018-11-15 2019-03-01 安徽通灵仿生科技有限公司 A kind of pulsation type conduit device assisting left ventricular function
CN210331245U (en) * 2019-05-05 2020-04-17 北京安生生物技术有限责任公司 Single saccule counterpulsation type left heart auxiliary device

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Publication number Priority date Publication date Assignee Title
WO2003068292A1 (en) * 2002-02-11 2003-08-21 National University Of Singapore Physiologically compatible cardiac assist device and method
CN204766756U (en) * 2015-04-30 2015-11-18 黄志辉 Sacculus heart counterpulsation ware
CN106668965A (en) * 2017-01-06 2017-05-17 张乐峰 Balloon counterpulsation driven mechanical auxiliary circulating device with valves
CN107158549A (en) * 2017-06-29 2017-09-15 吴强 For regulating and controlling left ventricle capacity to improve the servicing unit of Cardial pump function
CN109395185A (en) * 2018-11-15 2019-03-01 安徽通灵仿生科技有限公司 A kind of pulsation type conduit device assisting left ventricular function
CN210331245U (en) * 2019-05-05 2020-04-17 北京安生生物技术有限责任公司 Single saccule counterpulsation type left heart auxiliary device

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110559497A (en) * 2019-09-19 2019-12-13 厦门大学附属第一医院 heart auxiliary support balloon system, manufacturing method thereof and heart auxiliary device
CN110559497B (en) * 2019-09-19 2024-02-09 厦门大学附属第一医院 Heart auxiliary stent balloon system, manufacturing method thereof and heart auxiliary device

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