CN110169863A - A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops - Google Patents

A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops Download PDF

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Publication number
CN110169863A
CN110169863A CN201910434547.5A CN201910434547A CN110169863A CN 110169863 A CN110169863 A CN 110169863A CN 201910434547 A CN201910434547 A CN 201910434547A CN 110169863 A CN110169863 A CN 110169863A
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CN
China
Prior art keywords
temperature
cordate houttuynia
drop bottle
eye drop
exclusively used
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910434547.5A
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Chinese (zh)
Inventor
张沛
廖远征
黄筱萍
李涛
熊晓明
程亮
聂飞
胥勤
余建军
杨强
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SICHUAN SUNNYHOPE PHARMACEUTICAL CO Ltd
Original Assignee
SICHUAN SUNNYHOPE PHARMACEUTICAL CO Ltd
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Filing date
Publication date
Application filed by SICHUAN SUNNYHOPE PHARMACEUTICAL CO Ltd filed Critical SICHUAN SUNNYHOPE PHARMACEUTICAL CO Ltd
Priority to CN201910434547.5A priority Critical patent/CN110169863A/en
Publication of CN110169863A publication Critical patent/CN110169863A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

The invention discloses a kind of eye drop bottles for being exclusively used in cordate houttuynia eye drops, are related to drug packages Material Field.The eye drop bottle includes body, internal plug and outer cover;There is opening, the internal plug is set to the open interior, closes the opening with opening cooperation at the top of the body;The outer cover setting is connected to the outside of the opening;The body and the internal plug are made of polyester material.In the eye drop bottle, it is raw material that directly the body of contact medical fluid and internal plug, which are all made of polyester, raw material obtain body and internal plug by different process process injection molding, make the two that there is suitable flexible and hardness, obtained eye drop bottle good airproof performance is combined, the effective component in medical fluid is not absorbed, medical fluid quality is not impacted, the shelf-life of cordate houttuynia eye drops can effectively be extended, improve clinical application safety.

Description

A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops
Technical field
The present invention relates to drug packages Material Fields, in particular to a kind of eye drops for being exclusively used in cordate houttuynia eye drops Bottle.
Background technique
Medical Packing Materials product is divided into I class, II class and III class.Wherein, I class Medical Packing Materials refer to directly contact drug and directly use Key works Drug packing material, container;II class Medical Packing Materials refer to directly contact drug, but convenient for cleaning, in actual use, through clear It is needed after washing and can be with the Key works Drug packing of sterilization and material, container.Important component of the Medical Packing Materials as drug, it is adjoint Pharmaceutical production, circulation and use overall process, quality directly affects drug quality.Medical Packing Materials not only affect drug Storage, circulation and beautiful, and may occur with certain components in drug physics, chemical reaction and influence drug quality, Even certain harmful substances may invade drug, become the hidden danger of clinical application.
Cordate houttuynia eye drops are the drugs prepared using cordate houttuynia as primary raw material, have heat-clearing, are detoxified, the effect of dampness removing, It is mainly used for attacking caused acute conjunctivitis, acute contagious conjunctivitis, epidemic keratoconjunctivitis symptoms include two shouting pains, eye itching, streams on wind-heat epidemic disease poison Tear;Acute catarrhal conjunctivitis, the symptoms such as epidemic keratoconjunctivitis.For cordate houttuynia eye drops, applicant has applied for that product is special Benefit: a kind of cordate houttuynia eye drops and preparation method thereof, Authorization Notice No. CN104983876B.It is carried out further to the product Found in research process: using conventional PE(polyethylene) eye drop bottle packaging cordate houttuynia eye drops, PE can absorb in medical fluid Main component methylnonanone (C11H22O), so as to cause cordate houttuynia eye drops, content sharply declines in normal placement process, Cause medication hidden danger.
Summary of the invention
Goal of the invention of the invention is: in view of the above problems, providing a kind of cordate houttuynia eye drops that are exclusively used in Eye drop bottle, the body and internal plug of the eye drop bottle are all made of polyester (PET) material and are made, do not absorb in cordate houttuynia eye drops at Point, it can effectively extend the shelf-life of cordate houttuynia eye drops.
The technical solution adopted by the invention is as follows:
A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops comprising body, internal plug and outer cover;Have at the top of the body and opens Mouthful, the internal plug is set to the open interior, closes the opening with opening cooperation;The outer cover setting is connected to institute State the outside of opening;The body and the internal plug are made of polyester material.
By adopting the above-described technical solution, the body and internal plug of directly contact medical fluid are all made of polyester material and are made, no The effective component in medical fluid is absorbed, the shelf-life of cordate houttuynia can be effectively extended.
A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops of the invention, the preparation method of the body include the following steps:
Polyester plastics particle is taken to stir 1-5min, then the dry 3-4h at 150 ± 20 DEG C;
Plastic-injection moulding machine is opened, setting nozzle temperature is 280 ± 10 DEG C, and first, second and third section of temperature is 265 ± 10 DEG C, the Four sections of temperature are 260 ± 10 DEG C, and tunnel inlets, right runner, Zuo Liudao temperature are 240 ± 10 DEG C, and cooling temperature is 14-24 DEG C, It is 70-150 that each note, which presses force value,;After temperature reaches setting value and constant temperature 20-40min, by dried material injected plastic Technological parameter base is arranged in injection (mo(u)lding) machine;
Biaxial orientation molding machine is opened, setting heating light tube electric voltage value first segment is 50 ± 10%, and second segment is 28 ± 10%, third Section is 48 ± 10%, and technological parameter is arranged, blank obtained is added, by blank blow molding to obtain the final product.
A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops of the invention, the preparation method of the internal plug include following step It is rapid:
Polyester plastics particle is taken to stir 1-5min, then the dry 3-4h at 150 ± 20 DEG C;
Plastic-injection moulding machine is opened, setting nozzle temperature is 285 ± 10 DEG C, and the first temperature is 295 ± 10 DEG C, second segment temperature It is 290 ± 10 DEG C, third section temperature is 280 ± 10 DEG C, and preceding mould temperature is 14-24 DEG C, and rear mold temperature is 45 ± 10 DEG C;To temperature After reaching setting value and constant temperature 20-40min, by dried material injected plastic injection (mo(u)lding) machine, technological parameter is set and is molded Molding.
A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops of the invention, polyester plastics particle are selected from supplementary material or original The mixture of auxiliary material and leftover pieces, the content of leftover pieces is no more than 50% in mixture.
By adopting the above-described technical solution, the body and internal plug that are prepared have suitable flexible and hardness, it is convenient for The two cooperation sealing, while quality of liquid medicine is not impacted.
A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops of the invention, the outer cover use modified polyethylene material system At the preparation method of the outer cover includes the following steps:
Appropriate low density polyethylene (LDPE), high density polyethylene (HDPE), green color masterbatch are taken, 1-5min is stirred;
Plastic-injection moulding machine is opened, setting nozzle temperature is 210 ± 10 DEG C, and first segment temperature is 200 ± 10 DEG C, second segment temperature Degree is 190 ± 10 DEG C, third and fourth section of temperature is 180 ± 10 DEG C, and cooling temperature is 14-24 DEG C;Reach setting value and perseverance to temperature After warm 20-40min, by agitated material injected plastic injection (mo(u)lding) machine, technological parameter injection molding is set.
A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops of the invention is low density polyethylene (LDPE), high density polyethylene (HDPE), green The mass ratio of color color masterbatch is 3-6:18-25:1.
A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops of the invention, the internal plug include water dropper interconnected and Obturating plug, the obturating plug are set to the open interior;Internal plug is additionally provided with dropping liquid channel, and the water dropper is run through in the dropping liquid channel With the obturating plug, it is connected to the body.
By adopting the above-described technical solution, obturating plug is set to open interior, formed therebetween face-to-face, firmly to hard Sealing, sealing effect are good.
A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops of the invention, the dropping liquid channel are located at the top of the water dropper Place is provided with liquid droping port, and the liquid droping port is truncated cone-shaped, and the lesser bottom surface of area is close to the obturating plug.
A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops of the invention is provided in the inner top wall of the outer cover close The dropping liquid channel is closed in Feng Zhu, the sealing column and liquid droping port cooperation.
In conclusion by adopting the above-described technical solution, the beneficial effects of the present invention are:
The present invention provides a kind of eye drop bottle for being exclusively used in cordate houttuynia eye drops, in the eye drop bottle, direct contact medical fluid It is raw material that body and internal plug, which are all made of polyester, and raw material obtain body and internal plug by different process process injection molding, make There is the two suitable flexible and hardness, the eye drop bottle good airproof performance combined not to absorb the effective component in medical fluid, no Medical fluid quality is impacted, the shelf-life of cordate houttuynia eye drops can be effectively extended, improves clinical application safety.
Detailed description of the invention
Examples of the present invention will be described by way of reference to the accompanying drawings, in which:
Fig. 1 is the structural schematic diagram for the eye drop bottle for being exclusively used in cordate houttuynia eye drops that the embodiment of the present invention 1 provides;
Fig. 2 is the diagrammatic cross-section of the internal plug for the eye drop bottle for being exclusively used in cordate houttuynia eye drops that the embodiment of the present invention 1 provides;
Fig. 3 is the characteristic spectrum for the cordate houttuynia eye drops that the embodiment of the present invention 5 provides.
Specific embodiment
All features disclosed in this specification or disclosed all methods or in the process the step of, in addition to mutually exclusive Feature and/or step other than, can combine in any way.
Any feature disclosed in this specification (including any accessory claim, abstract), unless specifically stated, It is replaced by other equivalent or with similar purpose alternative features.That is, unless specifically stated, each feature is a series of An example in equivalent or similar characteristics.
Embodiment 1
As shown in Figure 1, the present embodiment provides a kind of eye drop bottles for being exclusively used in cordate houttuynia comprising body 1, internal plug 2 and outer cover 3, wherein internal plug 2 is connected in body 1, and outer cover 3 is connected to outside body 1.Body 1 may be configured as being suitable for drop in the prior art The arbitrary shape of eye agent bottle, it is preferably cylindrical.Opening 11 is provided at the top of body 1, internal plug 2 is set to inside opening 11, with The opening 11 is closed in 11 cooperation of opening.
Internal plug 2 includes water dropper 21, obturating plug 22 and dropping liquid channel 23.Water dropper 21 and obturating plug 22 are connected with each other, and obturating plug 22 is set It is placed in inside opening 11, cooperates closing opening 11 with opening 11.Water dropper 21 and obturating plug 22 are run through in dropping liquid channel 23, connect with body 1 It is logical, to ooze medical fluid.The top in dropping liquid channel 23 is liquid droping port 24, and liquid droping port 24 is located at the top of water dropper, and is set as truncated cone-shaped, The lesser bottom surface of truncated cone-shaped area is close to obturating plug 22.
The mode that outer cover 3 is connected through a screw thread is connected to body 1.The inside top of outer cover 3 is provided with sealing column 31, sealing Column 31 and liquid droping port 24 cooperate, to close dropping liquid channel 23.It should be noted that body 1 and internal plug 2 are adopted in the present embodiment It is made of polyester material, outer cover 3 is made of modified polyethylene material.It should be noted that in other embodiments, outer cover 3 Other materials can also be used, (such as ABS) is made.
Embodiment 2
The present embodiment provides a kind of PET eye drop bottle bodies and preparation method thereof, and this method can be used for the drop provided in embodiment 1 The preparation of the body of eye agent bottle, specifically comprises the following steps:
Step 1: weighing suitable polyester plastics particle, puts into clean hybrid storage vat, stirs 1-5min.It has stirred Cheng Hou is transferred in drying machine, the dry 3-4h at 150 ± 20 DEG C.Wherein, polyester plastics particle is selected from supplementary material or former auxiliary Expect the mixture with leftover pieces, the content of leftover pieces is no more than 50% in mixture.
Step 2: plastic-injection moulding machine is opened, setting nozzle temperature is 280 ± 10 DEG C, and first, second and third section of temperature is 265 ± 10 DEG C, the 4th section of temperature is 260 ± 10 DEG C, and tunnel inlets, right runner, Zuo Liudao temperature are 240 ± 10 DEG C, cooling temperature Degree is 14-24 DEG C, and it is 70-150 that each note, which presses force value,.It, will be dried after temperature reaches setting value and constant temperature 20-40min Material injected plastic injection (mo(u)lding) machine opens oil pump motor, adjusts open mold according to mold thickness and projects pressure, speed, position It sets, the technological parameters such as time carry out base.The technological parameter used in the present embodiment is as shown in table 1.
1 blanking mold parameter of table
Step 3: PET biaxial orientation molding machine is opened, setting heating light tube electric voltage value first segment is 50 ± 10%, second segment 28 ± 10%, third section is 48 ± 10%.According to the size of bottle embryo, thickness, height equal-specification, corresponding technological parameter is set.This reality The design parameter applied in example is as shown in table 2.After the operation of heating box exhaust fan, blank obtained is added, blank is blow molded It forms to obtain the final product.
2 blank blow molding parameter of table
Embodiment 3
The present embodiment provides a kind of PET eye drop bottle internal plugs and preparation method thereof, and this method can be used for the drop provided in embodiment 1 The preparation of the internal plug of eye agent bottle, specifically comprises the following steps:
Step 1: weighing suitable polyester plastics particle, puts into clean hybrid storage vat, stirs 1-5min.It has stirred Cheng Hou is transferred in drying machine, the dry 3-4h at 150 ± 20 DEG C.Wherein, polyester plastics particle is selected from supplementary material or former auxiliary Expect the mixture with leftover pieces, the content of leftover pieces is no more than 50% in mixture.
Step 2: opening plastic-injection moulding machine, and setting nozzle temperature is 285 ± 10 DEG C, and the first temperature is 295 ± 10 DEG C, second segment temperature is 290 ± 10 DEG C, and third section temperature is 280 ± 10 DEG C, and preceding mould temperature is 14-24 DEG C, and rear mold temperature is 45 ±10℃;After temperature reaches setting value and constant temperature 20-40min, dried material injected plastic injection (mo(u)lding) machine is opened Oil pump motor, by setting technological parameter, injection molding shown in table 3.It should be noted that the technological parameter in table 3 is according to this Mold used in embodiment it is identified, can be adjusted according to actual needs in other embodiments.
3 internal plug of table prepares die parameters
Embodiment 4
The present embodiment provides a kind of PET eye drop bottle outer covers and preparation method thereof, and this method can be used for the drop provided in embodiment 1 The preparation of the outer cover of eye agent bottle, specifically comprises the following steps:
Step 1: low density polyethylene (LDPE), high density polyethylene (HDPE), green color masterbatch are weighed respectively for 3-6:18-25:1 in mass ratio, is thrown Enter in clean hybrid storage vat, stirs 1-5min.
Step 2: opening plastic-injection moulding machine, and setting nozzle temperature is 210 ± 10 DEG C, and the first temperature is 200 ± 10 DEG C, second segment temperature is 190 ± 10 DEG C, third and fourth section of temperature is 180 ± 10 DEG C, and cooling temperature is 14-24 DEG C.It is reached to temperature To after setting value and constant temperature 20-40min, by agitated material injected plastic injection (mo(u)lding) machine, oil pump motor is opened, by table 4 Shown setting technological parameter, injection molding.It should be noted that the technological parameter in table 4 is according to used in the present embodiment Mold it is identified, can be adjusted according to actual needs in other embodiments.
4 outer cover of table prepares die parameters
Embodiment 5
The present embodiment verifies the performance of the eye drop bottle provided by the invention for being exclusively used in cordate houttuynia eye drops, is it into one Step application provides foundation.
Experimental method: in large-scale production process, the PET eye drop bottle liquid drug that will be produced in embodiment 2, then at random It selects half and adds PE internal plug in the prior art, spiral cover is control group.The other half adds the PET internal plug produced in embodiment 3, rotation Lid is experimental group.In experimentation, two groups take the filling product of half to be inverted respectively, the other half is normal to place, respectively the 1st, 7, 14,21,28 days sample detection contents.
Characteristic spectrum: as shown in figure 3,6 characteristic peaks should be presented in test sample characteristic spectrum, wherein 4 peaks should be respectively at α-pine tar Alcohol reference substance, 4- terpineol reference substance, methylnonanone reference substance, Bronyl acetate reference substance peak retention time are consistent, with first The positive corresponding peak of nonanone reference substance of base is the peak S, calculate each characteristic peak and the peak S relative retention time should specified value ± 5% it It is interior, it is specified that value are as follows: the peak 0.782(1), the peak 0.820(2), the peak 0.878(3), the peak 0.909(4), 1.000(peak S), the peak 1.052( 5).
Testing result is as shown in table 5.
5 sample size testing result of table
As shown in Table 5, with the increase of standing time, in control group, the content of sample is being gradually decreased, and is being placed the 28th day Afterwards, providing lower than standard has occurred in content, and product is unqualified.And the content of sample is without significant change in experimental group.Thus may be used See, the eye drop bottle provided by the invention for being exclusively used in cordate houttuynia eye drops does not absorb the effective component in medical fluid, can effectively extend The shelf-life of cordate houttuynia eye drops.
The invention is not limited to specific embodiments above-mentioned.The present invention, which expands to, any in the present specification to be disclosed New feature or any new combination, and disclose any new method or process the step of or any new combination.

Claims (9)

1. a kind of eye drop bottle for being exclusively used in cordate houttuynia eye drops, which is characterized in that it includes body, internal plug and outer cover;It is described There is opening, the internal plug is set to the open interior, closes the opening with opening cooperation at the top of body;It is described outer Lid setting is connected to the outside of the opening;The body and the internal plug are made of polyester material.
2. the eye drop bottle according to claim 1 for being exclusively used in cordate houttuynia eye drops, which is characterized in that the system of the body Preparation Method includes the following steps:
Polyester plastics particle is taken to stir 1-5min, then the dry 3-4h at 150 ± 20 DEG C;
Plastic-injection moulding machine is opened, setting nozzle temperature is 280 ± 10 DEG C, and first, second and third section of temperature is 265 ± 10 DEG C, the Four sections of temperature are 260 ± 10 DEG C, and tunnel inlets, right runner, Zuo Liudao temperature are 240 ± 10 DEG C, and cooling temperature is 14-24 DEG C, It is 70-150 that each note, which presses force value,;After temperature reaches setting value and constant temperature 20-40min, by dried material injected plastic Technological parameter base is arranged in injection (mo(u)lding) machine;
Biaxial orientation molding machine is opened, setting heating light tube electric voltage value first segment is 50 ± 10%, and second segment is 28 ± 10%, third Section is 48 ± 10%, and technological parameter is arranged, blank obtained is added, by blank blow molding to obtain the final product.
3. the eye drop bottle according to claim 1 for being exclusively used in cordate houttuynia eye drops, which is characterized in that the system of the internal plug Preparation Method includes the following steps:
Polyester plastics particle is taken to stir 1-5min, then the dry 3-4h at 150 ± 20 DEG C;
Plastic-injection moulding machine is opened, setting nozzle temperature is 285 ± 10 DEG C, and first segment temperature is 295 ± 10 DEG C, second segment temperature Degree is 290 ± 10 DEG C, and third section temperature is 280 ± 10 DEG C, and preceding mould temperature is 14-24 DEG C, and rear mold temperature is 45 ± 10 DEG C;To temperature After degree reaches setting value and constant temperature 20-40min, by dried material injected plastic injection (mo(u)lding) machine, technological parameter is set and is infused It is moulded into type.
4. the eye drop bottle according to claim 2 or 3 for being exclusively used in cordate houttuynia eye drops, which is characterized in that polyester plastics Particle is selected from the mixture of supplementary material or supplementary material and leftover pieces, and the content of leftover pieces is no more than 50% in mixture.
5. the eye drop bottle according to claim 1 for being exclusively used in cordate houttuynia eye drops, which is characterized in that the outer cover uses Modified polyethylene material is made;The preparation method of the outer cover includes the following steps:
Appropriate low density polyethylene (LDPE), high density polyethylene (HDPE), green color masterbatch are taken, 1-5min is stirred;
Plastic-injection moulding machine is opened, setting nozzle temperature is 210 ± 10 DEG C, and first segment temperature is 200 ± 10 DEG C, second segment temperature Degree is 190 ± 10 DEG C, third and fourth section of temperature is 180 ± 10 DEG C, and cooling temperature is 14-24 DEG C;Reach setting value and perseverance to temperature After warm 20-40min, by agitated material injected plastic injection (mo(u)lding) machine, technological parameter injection molding is set.
6. the eye drop bottle according to claim 5 for being exclusively used in cordate houttuynia eye drops, which is characterized in that low density polyethylene Alkene, high density polyethylene (HDPE), green color masterbatch mass ratio be 3-6:18-25:1.
7. the eye drop bottle according to claim 1 for being exclusively used in cordate houttuynia eye drops, which is characterized in that the internal plug includes Water dropper and obturating plug interconnected, the obturating plug are set to the open interior;Internal plug is additionally provided with dropping liquid channel, the dropping liquid The water dropper and the obturating plug are run through in channel, are connected to the body.
8. the eye drop bottle according to claim 7 for being exclusively used in cordate houttuynia eye drops, which is characterized in that the dropping liquid channel Liquid droping port is provided at the top of the water dropper, the liquid droping port is truncated cone-shaped, and the lesser bottom surface of area is close to the obturating plug.
9. the eye drop bottle according to claim 8 for being exclusively used in cordate houttuynia eye drops, which is characterized in that the outer cover it is interior Sealing column is provided on portion's roof, the dropping liquid channel is closed in the sealing column and liquid droping port cooperation.
CN201910434547.5A 2019-05-23 2019-05-23 A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops Pending CN110169863A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910434547.5A CN110169863A (en) 2019-05-23 2019-05-23 A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910434547.5A CN110169863A (en) 2019-05-23 2019-05-23 A kind of eye drop bottle being exclusively used in cordate houttuynia eye drops

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Publication Number Publication Date
CN110169863A true CN110169863A (en) 2019-08-27

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2112593U (en) * 1991-12-18 1992-08-12 王谟公 Pug-in/type composite tension seal bottle plug
EP1518525B1 (en) * 2003-09-26 2009-09-02 Shinko Chemical Co., Ltd. A droplet nozzle for use in eye drop container
CN201578573U (en) * 2009-12-13 2010-09-15 程继勇 Combined cap for soft bag or plastic bottle
CN202751591U (en) * 2012-07-05 2013-02-27 何伟 Antibacterial eye drop bottle
CN105233397A (en) * 2015-10-14 2016-01-13 广东三蓝药业股份有限公司 Novel eye drop bottle
CN107151366A (en) * 2017-06-01 2017-09-12 永新股份(黄山)包装有限公司 A kind of high temperature high voltage resistant cracking resistance suction nozzle and its production method
CN209301452U (en) * 2018-07-04 2019-08-27 沈阳何氏眼产业集团有限公司 Embedded bellows eye drop bottle

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2112593U (en) * 1991-12-18 1992-08-12 王谟公 Pug-in/type composite tension seal bottle plug
EP1518525B1 (en) * 2003-09-26 2009-09-02 Shinko Chemical Co., Ltd. A droplet nozzle for use in eye drop container
CN201578573U (en) * 2009-12-13 2010-09-15 程继勇 Combined cap for soft bag or plastic bottle
CN202751591U (en) * 2012-07-05 2013-02-27 何伟 Antibacterial eye drop bottle
CN105233397A (en) * 2015-10-14 2016-01-13 广东三蓝药业股份有限公司 Novel eye drop bottle
CN107151366A (en) * 2017-06-01 2017-09-12 永新股份(黄山)包装有限公司 A kind of high temperature high voltage resistant cracking resistance suction nozzle and its production method
CN209301452U (en) * 2018-07-04 2019-08-27 沈阳何氏眼产业集团有限公司 Embedded bellows eye drop bottle

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