CN106800729B - A kind of preparation method of high grade of transparency medical PVC stiff sheet - Google Patents
A kind of preparation method of high grade of transparency medical PVC stiff sheet Download PDFInfo
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- CN106800729B CN106800729B CN201611265216.6A CN201611265216A CN106800729B CN 106800729 B CN106800729 B CN 106800729B CN 201611265216 A CN201611265216 A CN 201611265216A CN 106800729 B CN106800729 B CN 106800729B
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L27/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers
- C08L27/02—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L27/04—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment containing chlorine atoms
- C08L27/06—Homopolymers or copolymers of vinyl chloride
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B11/00—Wrapping, e.g. partially or wholly enclosing, articles or quantities of material, in strips, sheets or blanks, of flexible material
- B65B11/50—Enclosing articles, or quantities of material, by disposing contents between two sheets, e.g. pocketed sheets, and securing their opposed free margins
- B65B11/52—Enclosing articles, or quantities of material, by disposing contents between two sheets, e.g. pocketed sheets, and securing their opposed free margins one sheet being rendered plastic, e.g. by heating, and forced by fluid pressure, e.g. vacuum, into engagement with the other sheet and contents, e.g. skin-, blister-, or bubble- packaging
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/011—Nanostructured additives
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2201/00—Properties
- C08L2201/10—Transparent films; Clear coatings; Transparent materials
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/02—Applications for biomedical use
Abstract
The invention discloses a kind of preparation methods of high grade of transparency medical PVC stiff sheet, belong to medical material preparation technical field.The present invention first with after silane coupler modified nano silica with heat stabilizer, plasticizer and polyvinyl chloride mixing, again using dimethicone as lubricant, ultramarine is the yellow agent that disappears, addition self-control modified manometer silicon dioxide mixing, finally formed through extruding pelletization post-calendering, high grade of transparency medical PVC stiff sheet is made, the present invention is using different temperatures gradient and speed of agitator to polyvinyl chloride processing, make the broken refinement of polyvinyl chloride particles, improve transparency after molding, modified manometer silicon dioxide is added again, it penetrates into polyvinyl chloride near defect and remaining unsaturated double-bond, and it has an effect with unsaturated electron cloud, reticular structure is combined into polyvinyl chloride macromolecular, while raising material transparent is spent, achieve the purpose that strengthening and toughening and improves photostability, it is not high to efficiently solve traditional PVC stiff sheet transparency, easily jaundice The problem of.
Description
Technical field
The invention discloses a kind of preparation methods of high grade of transparency medical PVC stiff sheet, belong to medical material technology of preparing neck
Domain.
Background technique
PVC is one of five big thermoplastic synthetic resins, is widely used in building, automobile space flight, electronics, electric appliance, packaging etc.
Field.PVC stiff sheet has the advantage of intensity, the transparency, dielectric properties, anti-flammability etc., is widely used in packaging field.
The blister package of drug is also known as blister, is placed in drug through vacuum suction moulding or cold stamping shaped
In the pit (referred to as bubble-cap or blister) for packing stiff sheet, then it is hot therewith with aluminium foil with the Key works Drug packing for being coated with heat sealable coating
Envelope forms unit package, so that drug be made to obtain safeguard protection.Currently, the packaging of large grained pill in the market, general to use
Cold forming PVC stiff sheet is by medicinal pill package in inside.
With widening for PVC stiff sheet application field, importance of the transparency in terms of product quality becomes increasingly conspicuous.It is existing
Medical PVC stiff sheet during the preparation process, is influenced by polyvinyl chloride raw material and processing and forming technology parameter, causes gained stiff sheet transparent
Degree is not high, easily turns to be yellow in use process, seriously limits the application of PVC stiff sheet and promotes.
In the process of PVC stiff sheet, polyvinyl chloride resin undergo softening, Particle Breakage, melting, fluidity of molten by it is small to
Big and strand rearranges the change procedures such as molding.In order to guarantee the transparency of PVC stiff sheet, it is desirable that PVC resin plasticization process
In uniformity with higher.And the factors such as the molecular vibrational temperature of polyvinyl chloride resin, molecular structure, particle shape and " flake " are determined
Determine the technological parameter of machine-shaping, and then determines the transparency of stiff sheet.Further, since polymer containing double bonds is easy to inhale
It receives visible light and generates the transfer of energy level, cause the reduction of transparency, certain defect sturctures contain double bond in polyvinyl chloride resin, can lead
Identical problem is caused, to make PVC product that there is the excellent transparency, it is necessary to reduce the chemical imperfection structure of PVC.Therefore, PVC tree
The raising of rouge sole mass and the chemical imperfection structure for making up PVC are to guarantee precondition and the people of the PVC stiff sheet transparency
Technical problem urgently to be resolved.
Summary of the invention
Present invention mainly solves the technical issues of: for conventional medical PVC stiff sheet during the preparation process, by polyvinyl chloride original
Material and processing and forming technology parameter influence, and cause gained stiff sheet transparency not high, easily turn to be yellow in use process, limit it using model
The problem of enclosing provides a kind of addition self-control modified manometer silicon dioxide, under the conditions of different temperatures gradient and speed of agitator, system
The standby method for obtaining high grade of transparency medical PVC stiff sheet, the invention firstly uses silane coupler modified nano silicas, then with
Bis(lauroyloxy)dioctyltin is heat stabilizer, and trioctyl trimellitate (TOTM) is plasticizer, with polyvinyl chloride in relative low temperature and low
It is mixed under fast stirring condition, then using dimethicone as lubricant, ultramarine is the yellow agent that disappears, addition self-control modified manometer silicon dioxide
Mixing enters auxiliary agent in polyvinyl chloride particles hole under stirring and heat effect under the conditions of relatively-high temperature and high-speed stirred,
Keep particle more densely cross-linked, surface is more smooth, finally forms through extruding pelletization post-calendering, high grade of transparency medical PVC stiff sheet is made,
The present invention makes full use of different temperatures gradient and speed of agitator to polyvinyl chloride processing, makes the broken refinement of polyvinyl chloride particles, obtains
To partial size and plasticized granule of uniform morphology, transparency after molding is improved, recycles the modified manometer silicon dioxide of addition, is seeped
Enter in polyvinyl chloride near defect and remaining unsaturated double-bond, and have an effect with unsaturated electron cloud, with polyvinyl chloride
Macromolecular is incorporated into reticular structure, while further increasing material transparent and spend, reaches strengthening and toughening and improves light and stablize
Property purpose, it is not high to efficiently solve traditional PVC stiff sheet transparency, easily jaundice the problem of.
In order to solve the above-mentioned technical problem, the technical scheme adopted by the invention is that:
(1) 3~5g Silane coupling reagent KH-570 is weighed, pouring into and filling 200~300mL mass fraction is 85~90% ethyl alcohol
In the beaker of solution, then beaker immigration digital display tested the speed in constant temperature blender with magnetic force, in temperature be 60~65 DEG C, revolving speed 300
Under the conditions of~400r/min, constant temperature is stirred to react 60~90min, and to the end of reacting, material in beaker is transferred in three-necked flask,
And 8~10g nano silica is added, dropwise addition mass fraction is 3~5% hydrochloric acid, adjusts pH to 3.6~4.0, then three mouthfuls are burnt
Bottle is transferred to sonic oscillation instrument, disperses 45~60min with 50~60kHz frequency ultrasound,
(2) to the end of ultrasonic disperse, material in above-mentioned three-necked flask is transferred to centrifuge, is turned with 6000~8000r/min
Speed 10~20min of centrifuge separation collects lower sediment thing, and is that 80% ethanol solution washs 3~5 times, then will wash with mass fraction
Lower sediment thing after washing is transferred in vacuum freezing drying oven, and dry 48~72h obtains modified manometer silicon dioxide；
(3) according to parts by weight, 100~120 parts of polyvinyl chloride, 0.8~1.5 part of tin dilaurate di-n-octyl are successively taken
Tin, 3~5 parts of trioctyl trimellitate (TOTM)s, 2~4 parts of dimethicones, 3~5 parts of above-mentioned gained modified manometer silicon dioxides, 0.1~
0.3 portion of ultramarine, first by the polyvinyl chloride, Bis(lauroyloxy)dioctyltin, trioctyl trimellitate (TOTM) is poured into batch mixer, in
Temperature is 60~80 DEG C, and under the conditions of revolving speed is 200~300r/min, constant temperature is stirred 30~45min, adds described two
Methyl-silicone oil, modified manometer silicon dioxide and ultramarine, continuing at temperature is 90~100 DEG C, and revolving speed is 800~1000r/min item
Under part, constant temperature is stirred to react 45~60min；
(4) to the end of above-mentioned constant temperature is stirred to react, temperature in above-mentioned batch mixer is risen to 110~120 DEG C, is in revolving speed
Under the conditions of 1800~2000r/min, constant temperature 20~30min of high-speed stirred, after naturally cool to 50~60 DEG C, by object in batch mixer
Material is transferred in double screw extruder, is rolled in flakes after extruding pelletization through calender, is removed up to high grade of transparency medical PVC stiff sheet.
Application method of the invention is: capsule being fitted into medicament packing machine hopper first, opening machine makes to fill capsule
Enter in high grade of transparency medical PVC stiff sheet produced by the present invention, it is then that the PVC stiff sheet after the full capsule of filling is compound using heating
PVC stiff sheet adhesive surface is heated to 80~90 DEG C, then coats medicinal adhesive material, control adhesive layer coating in adhesive surface by mode
With a thickness of 1.4~1.6g/m2, coating speed is 60~80m/min, then by medicinal aluminum foil material be fitted on adhesive layer heat-sealing at
Shape, control heat seal strength are 8~14N/15mm, finally that the stiff sheet material left after heat-sealing is cooling.Through detecting, the present invention
High grade of transparency medical PVC stiff sheet transparency obtained is higher, light transmittance up to 90.6~93.4%, longitudinal tensile strength up to 58.6~
60.2MPa, transverse tensile strength is up to 52.7~54.3MPa, and longitudinal stretching rate is up to 99.6~102.3%, and cross directional stretch rate is up to 40.1
~43.6%, notch impact strength is up to 8.7~9.8KJ/m2, and PVC stiff sheet of the present invention has preferable ageing-resistant, yellowing resistance
Can, effectively improve 12~16 months stiff sheet materials'use service life.
The beneficial effects of the present invention are:
(1) high grade of transparency medical PVC stiff sheet transparency produced by the present invention is higher, and stability is preferable, and material self-force
Better performances are learned, drug protection and barrier action can be effectively played, guarantee drug integrality；
(2) high grade of transparency medical PVC stiff sheet produced by the present invention has preferable ageing-resistant, yellowing resistance energy, can be effective
The stiff sheet materials'use service life is improved, to improve the drug pot-life.
Specific embodiment
3~5g Silane coupling reagent KH-570 is weighed first, and pouring into and filling 200~300mL mass fraction is 85~90% ethyl alcohol
In the beaker of solution, then beaker immigration digital display tested the speed in constant temperature blender with magnetic force, in temperature be 60~65 DEG C, revolving speed 300
Under the conditions of~400r/min, constant temperature is stirred to react 60~90min, and to the end of reacting, material in beaker is transferred in three-necked flask,
And 8~10g nano silica is added, dropwise addition mass fraction is 3~5% hydrochloric acid, adjusts pH to 3.6~4.0, then three mouthfuls are burnt
Bottle is transferred to sonic oscillation instrument, disperses 45~60min with 50~60kHz frequency ultrasound, then to the end of ultrasonic disperse, by above-mentioned three
Material is transferred to centrifuge in mouth flask, is centrifugated 10~20min with 6000~8000r/min revolving speed, collects lower sediment thing,
And it is washed 3~5 times with mass fraction for 80% ethanol solution, then the lower sediment thing after washing is transferred to vacuum freezing drying oven
In, dry 48~72h obtains modified manometer silicon dioxide；Again according to parts by weight, 100~120 parts of polyvinyl chloride are successively taken, 0.8
~1.5 parts of Bis(lauroyloxy)dioctyltins, 3~5 parts of trioctyl trimellitate (TOTM)s, 2~4 parts of dimethicones, 3~5 parts of above-mentioned institutes
Obtain modified manometer silicon dioxide, 0.1~0.3 portion of ultramarine, first by the polyvinyl chloride, Bis(lauroyloxy)dioctyltin, inclined benzene
Three sour three monooctyl esters pour into batch mixer, are 60~80 DEG C in temperature, under the conditions of revolving speed is 200~300r/min, constant temperature stirring is mixed
30~45min is closed, the dimethicone, modified manometer silicon dioxide and ultramarine are added, continuing at temperature is 90~100
DEG C, under the conditions of revolving speed is 800~1000r/min, constant temperature is stirred to react 45~60min；Finally knot is stirred to react to above-mentioned constant temperature
Temperature in above-mentioned batch mixer is risen to 110~120 DEG C by beam, under the conditions of revolving speed is 1800~2000r/min, constant temperature high-speed stirring
20~30min is mixed, after naturally cool to 50~60 DEG C, material in batch mixer is transferred in double screw extruder, after extruding pelletization
In flakes through calender calendering, it removes up to high grade of transparency medical PVC stiff sheet.
Example 1
3g Silane coupling reagent KH-570 is weighed first, pours into the beaker for filling that 200mL mass fraction is 85% ethanol solution
In, then beaker immigration digital display tested the speed in constant temperature blender with magnetic force, in temperature be 60 DEG C, it is permanent under the conditions of revolving speed is 300r/min
Temperature is stirred to react 60min, to the end of reacting, material in beaker is transferred in three-necked flask, and 8g nano silica is added, drop
Adding mass fraction is 3% hydrochloric acid, adjusts pH to 3.6, then three-necked flask is transferred to sonic oscillation instrument, with the dispersion of 50kHz frequency ultrasound
Material in above-mentioned three-necked flask is transferred to centrifuge then to the end of ultrasonic disperse by 45min, with the centrifugation point of 6000r/min revolving speed
From 10min, lower sediment thing is collected, and washed 3 times for 80% ethanol solution with mass fraction, then by the lower sediment after washing
Object is transferred in vacuum freezing drying oven, and dry 48h obtains modified manometer silicon dioxide；Again according to parts by weight, 100 parts are successively taken
Polyvinyl chloride, 0.8 part of Bis(lauroyloxy)dioctyltin, 3 parts of trioctyl trimellitate (TOTM)s, 2 parts of dimethicones, 3 parts of above-mentioned gained
Modified manometer silicon dioxide, 0.1 portion of ultramarine, first by the polyvinyl chloride, Bis(lauroyloxy)dioctyltin, tri trimellitate is pungent
Ester pours into batch mixer, is 60 DEG C in temperature, and under the conditions of revolving speed is 200r/min, constant temperature is stirred 30min, adds described
Dimethicone, modified manometer silicon dioxide and ultramarine, continuing at temperature is 90 DEG C, permanent under the conditions of revolving speed is 8000r/min
Temperature is stirred to react 45min；Finally to the end of above-mentioned constant temperature is stirred to react, temperature in above-mentioned batch mixer is risen to 110 DEG C, in revolving speed
Under the conditions of 1800r/min, material in batch mixer is transferred to twin-screw after naturally cool to 50 DEG C by constant temperature high-speed stirred 20min
In extruder, roll in flakes after extruding pelletization through calender, removes up to high grade of transparency medical PVC stiff sheet.
This example operation is easy, in use, capsule is fitted into medicament packing machine hopper first, opening machine makes capsule
It is fitted into high grade of transparency medical PVC stiff sheet produced by the present invention, it is then that the PVC stiff sheet after the full capsule of filling is compound using heating
Mode, PVC stiff sheet adhesive surface is heated to 80 DEG C, then coat medicinal adhesive material in adhesive surface, control adhesive layer coating is thick
Degree is 1.4g/m2, coating speed 60m/min, then medicinal aluminum foil material is fitted in seal on adhesive layer and is shaped, control heat-sealing
Intensity is 8N/15mm, finally that the stiff sheet material left after heat-sealing is cooling.Through detecting, the high grade of transparency produced by the present invention
Medical PVC stiff sheet transparency is higher, and for light transmittance up to 90.6%, longitudinal tensile strength reaches 58.6MPa, and transverse tensile strength reaches
52.7MPa, longitudinal stretching rate is up to 99.6%, and for cross directional stretch rate up to 40.1%, notch impact strength reaches 8.7KJ/m2, and the present invention
PVC stiff sheet has preferable ageing-resistant, yellowing resistance energy, can effectively improve 12 months materials'use service life of stiff sheet.
Example 2
4g Silane coupling reagent KH-570 is weighed first, pours into the beaker for filling that 250mL mass fraction is 88% ethanol solution
In, then beaker immigration digital display tested the speed in constant temperature blender with magnetic force, in temperature be 63 DEG C, it is permanent under the conditions of revolving speed is 350r/min
Temperature is stirred to react 75min, to the end of reacting, material in beaker is transferred in three-necked flask, and 9g nano silica is added, drop
Adding mass fraction is 4% hydrochloric acid, adjusts pH to 3.8, then three-necked flask is transferred to sonic oscillation instrument, with the dispersion of 55kHz frequency ultrasound
Material in above-mentioned three-necked flask is transferred to centrifuge then to the end of ultrasonic disperse by 53min, with the centrifugation point of 7000r/min revolving speed
From 15min, lower sediment thing is collected, and washed 4 times for 80% ethanol solution with mass fraction, then by the lower sediment after washing
Object is transferred in vacuum freezing drying oven, and dry 60h obtains modified manometer silicon dioxide；Again according to parts by weight, 110 parts are successively taken
Polyvinyl chloride, 1.1 parts of Bis(lauroyloxy)dioctyltins, 4 parts of trioctyl trimellitate (TOTM)s, 3 parts of dimethicones, 4 parts of above-mentioned gained
Modified manometer silicon dioxide, 0.2 portion of ultramarine, first by the polyvinyl chloride, Bis(lauroyloxy)dioctyltin, tri trimellitate is pungent
Ester pours into batch mixer, is 70 DEG C in temperature, and under the conditions of revolving speed is 250r/min, constant temperature is stirred 37min, adds described
Dimethicone, modified manometer silicon dioxide and ultramarine, continuing at temperature is 95 DEG C, permanent under the conditions of revolving speed is 900r/min
Temperature is stirred to react 53min；Finally to the end of above-mentioned constant temperature is stirred to react, temperature in above-mentioned batch mixer is risen to 115 DEG C, in revolving speed
Under the conditions of 1900r/min, material in batch mixer is transferred to twin-screw after naturally cool to 55 DEG C by constant temperature high-speed stirred 25min
In extruder, roll in flakes after extruding pelletization through calender, removes up to high grade of transparency medical PVC stiff sheet.
This example operation is easy, in use, capsule is fitted into medicament packing machine hopper first, opening machine makes capsule
It is fitted into high grade of transparency medical PVC stiff sheet produced by the present invention, it is then that the PVC stiff sheet after the full capsule of filling is compound using heating
Mode, PVC stiff sheet adhesive surface is heated to 85 DEG C, then coat medicinal adhesive material in adhesive surface, control adhesive layer coating is thick
Degree is 1.5g/m2, coating speed 70m/min, then medicinal aluminum foil material is fitted in seal on adhesive layer and is shaped, control heat-sealing
Intensity is 11N/15mm, finally that the stiff sheet material left after heat-sealing is cooling.Through detecting, the high grade of transparency produced by the present invention
Medical PVC stiff sheet transparency is higher, and for light transmittance up to 92.1%, longitudinal tensile strength reaches 59.4MPa, and transverse tensile strength reaches
53.5MPa, longitudinal stretching rate is up to 100.8%, and for cross directional stretch rate up to 41.5%, notch impact strength reaches 9.2KJ/m2, and the present invention
PVC stiff sheet has preferable ageing-resistant, yellowing resistance energy, can effectively improve 14 months materials'use service life of stiff sheet.
Example 3
5g Silane coupling reagent KH-570 is weighed first, pours into the beaker for filling that 300mL mass fraction is 90% ethanol solution
In, then beaker immigration digital display tested the speed in constant temperature blender with magnetic force, in temperature be 65 DEG C, it is permanent under the conditions of revolving speed is 400r/min
Temperature is stirred to react 90min, to the end of reacting, material in beaker is transferred in three-necked flask, and 10g nano silica is added,
Dropwise addition mass fraction is 5% hydrochloric acid, adjusts pH to 4.0, then three-necked flask is transferred to sonic oscillation instrument, with 60kHz frequency ultrasound point
It dissipates 60min and material in above-mentioned three-necked flask is transferred to centrifuge then to the end of ultrasonic disperse, with the centrifugation of 8000r/min revolving speed
20min is separated, lower sediment thing is collected, and is that 80% ethanol solution washs 5 times, then the lower layer after washing is sunk with mass fraction
Starch is transferred in vacuum freezing drying oven, and dry 72h obtains modified manometer silicon dioxide；Again according to parts by weight, 120 are successively taken
Part polyvinyl chloride, 1.5 parts of Bis(lauroyloxy)dioctyltins, 5 parts of trioctyl trimellitate (TOTM)s, 4 parts of dimethicones, 5 parts of above-mentioned institutes
Obtain modified manometer silicon dioxide, 0.3 portion of ultramarine, first by the polyvinyl chloride, Bis(lauroyloxy)dioctyltin, tri trimellitate
Monooctyl ester pours into batch mixer, is 80 DEG C in temperature, under the conditions of revolving speed is 300r/min, constant temperature is stirred 45min, adds institute
The dimethicone stated, modified manometer silicon dioxide and ultramarine, continuing at temperature is 100 DEG C, and revolving speed is 1000r/min condition
Under, constant temperature is stirred to react 60min；Finally to the end of above-mentioned constant temperature is stirred to react, temperature in above-mentioned batch mixer is risen to 120 DEG C,
Under the conditions of revolving speed is 2000r/min, material in batch mixer is transferred to by constant temperature high-speed stirred 30min after naturally cool to 60 DEG C
In double screw extruder, roll in flakes after extruding pelletization through calender, removes up to high grade of transparency medical PVC stiff sheet.
This example operation is easy, in use, capsule is fitted into medicament packing machine hopper first, opening machine makes capsule
It is fitted into high grade of transparency medical PVC stiff sheet produced by the present invention, it is then that the PVC stiff sheet after the full capsule of filling is compound using heating
Mode, PVC stiff sheet adhesive surface is heated to 90 DEG C, then coat medicinal adhesive material in adhesive surface, control adhesive layer coating is thick
Degree is 1.6g/m2, coating speed 80m/min, then medicinal aluminum foil material is fitted in seal on adhesive layer and is shaped, control heat-sealing
Intensity is 14N/15mm, finally that the stiff sheet material left after heat-sealing is cooling.Through detecting, the high grade of transparency produced by the present invention
Medical PVC stiff sheet transparency is higher, and for light transmittance up to 93.4%, longitudinal tensile strength reaches 60.2MPa, and transverse tensile strength reaches
54.3MPa, longitudinal stretching rate is up to 102.3%, and for cross directional stretch rate up to 43.6%, notch impact strength reaches 9.8KJ/m2, and the present invention
PVC stiff sheet has preferable ageing-resistant, yellowing resistance energy, can effectively improve 16 months materials'use service life of stiff sheet.
Claims (1)
1. a kind of preparation method of high grade of transparency medical PVC stiff sheet, it is characterised in that specific preparation step are as follows:
(1) 3~5g Silane coupling reagent KH-570 is weighed, pouring into and filling 200~300mL mass fraction is 85~90% ethanol solutions
Beaker in, then beaker immigration digital display tested the speed in constant temperature blender with magnetic force, is 60~65 DEG C in temperature, revolving speed is 300~
Under the conditions of 400r/min, constant temperature is stirred to react 60~90min, and to the end of reacting, material in beaker is transferred in three-necked flask, and
It is added 8~10g nano silica, dropwises addition mass fraction is 3~5% hydrochloric acid, adjusting pH to 3.6~4.0, then by three-necked flask
It is transferred to sonic oscillation instrument, 45~60min is dispersed with 50~60kHz frequency ultrasound,
(2) to the end of ultrasonic disperse, material in above-mentioned three-necked flask is transferred to centrifuge, with 6000~8000r/min revolving speed from
The heart separates 10~20min, collects lower sediment thing, and washed 3~5 times for 80% ethanol solution with mass fraction, then will be after washing
Lower sediment thing be transferred in vacuum freezing drying oven, dry 48~72h obtains modified manometer silicon dioxide；
(3) according to parts by weight, 100~120 parts of polyvinyl chloride are successively taken, 0.8~1.5 part of Bis(lauroyloxy)dioctyltin, 3~
5 parts of trioctyl trimellitate (TOTM)s, 2~4 parts of dimethicones, 3~5 parts of above-mentioned gained modified manometer silicon dioxides, 0.1~0.3 part
Ultramarine, first by the polyvinyl chloride, Bis(lauroyloxy)dioctyltin, trioctyl trimellitate (TOTM) is poured into batch mixer, in temperature
It is 60~80 DEG C, under the conditions of revolving speed is 200~300r/min, constant temperature is stirred 30~45min, adds the dimethyl
Silicone oil, modified manometer silicon dioxide and ultramarine, continuing at temperature is 90~100 DEG C, under the conditions of revolving speed is 800~1000r/min,
Constant temperature is stirred to react 45~60min；
(4) to the end of above-mentioned constant temperature is stirred to react, temperature in above-mentioned batch mixer is risen to 110~120 DEG C, in revolving speed be 1800~
Under the conditions of 2000r/min, material in batch mixer is transferred to by constant temperature 20~30min of high-speed stirred after naturally cool to 50~60 DEG C
In double screw extruder, roll in flakes after extruding pelletization through calender, removes up to high grade of transparency medical PVC stiff sheet.
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| CN109776827A (en) * | 2019-01-28 | 2019-05-21 | 杨明忠 | A kind of preparation method of medical PVC stiff sheet |
| CN112745597B (en) * | 2020-12-28 | 2022-11-11 | 宜宾海丰和锐有限公司 | High-impact-resistance transparent PVC (polyvinyl chloride) medical material and preparation method thereof |
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| CN1488669A (en) * | 2002-10-08 | 2004-04-14 | 段秘彦 | Medicinal PVC sheet formulation |
| TW200932810A (en) * | 2008-01-28 | 2009-08-01 | Ind Tech Res Inst | Silica-polymeric resin composite and method for manufacturing the same |
| CN101831119A (en) * | 2010-03-17 | 2010-09-15 | 扬州凯尔化工有限公司 | Antibacterial PVC hard sheet suitable for packing medicament |
| CN106188963A (en) * | 2016-08-02 | 2016-12-07 | 扬州三星塑胶有限公司 | PVC sheet and preparation technology thereof |
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2016
- 2016-12-30 CN CN201611265216.6A patent/CN106800729B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1488669A (en) * | 2002-10-08 | 2004-04-14 | 段秘彦 | Medicinal PVC sheet formulation |
| TW200932810A (en) * | 2008-01-28 | 2009-08-01 | Ind Tech Res Inst | Silica-polymeric resin composite and method for manufacturing the same |
| CN101831119A (en) * | 2010-03-17 | 2010-09-15 | 扬州凯尔化工有限公司 | Antibacterial PVC hard sheet suitable for packing medicament |
| CN106188963A (en) * | 2016-08-02 | 2016-12-07 | 扬州三星塑胶有限公司 | PVC sheet and preparation technology thereof |
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| CN106800729A (en) | 2017-06-06 |
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