CN110157606A - A kind of gene sequencer turntable being convenient for changing - Google Patents

A kind of gene sequencer turntable being convenient for changing Download PDF

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Publication number
CN110157606A
CN110157606A CN201810347499.1A CN201810347499A CN110157606A CN 110157606 A CN110157606 A CN 110157606A CN 201810347499 A CN201810347499 A CN 201810347499A CN 110157606 A CN110157606 A CN 110157606A
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CN
China
Prior art keywords
bolt
chip placing
genetic chip
placing frame
groove
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201810347499.1A
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Chinese (zh)
Inventor
张炳强
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Qingdao Ruisike Biological Technology Co Ltd
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Qingdao Ruisike Biological Technology Co Ltd
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Priority to CN201810347499.1A priority Critical patent/CN110157606A/en
Publication of CN110157606A publication Critical patent/CN110157606A/en
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a kind of gene sequencer turntables being convenient for changing in gene sequencer disk technique field, including support rod, support rod is connected with bearing, bearing is connected with casing, casing connection has gripping mechanism, gripping mechanism includes pressing plate and the first bolt, first bolt is connect with press plate rotary, annular groove is equipped between casing and bearing outer wall, connecting rod is equipped with above support rod, connecting rod injects in annular groove, connecting rod is connected with bracket, sliding slot and groove are offered on bracket upper side wall, genetic chip placing frame is equipped between bracket, genetic chip placing frame side wall has sliding block and translot, spring is fixedly connected in the translot that genetic chip placing frame opens up, the spring other end is fixedly connected with convex block, genetic chip placing groove is offered in genetic chip placing frame, spiral shell at the right side mandril middle-end of genetic chip placing frame Line is connected with the second bolt, and the present invention is convenient for changing genetic chip placing frame to turntable good fixing effect.

Description

A kind of gene sequencer turntable being convenient for changing
Technical field
The present invention relates to gene sequencer disk technique field, specifically a kind of gene sequencer being convenient for changing, which is used, to be turned Disk.
Background technique
Gene is the basic unit of heredity, carries the gene or RNA sequence of hereditary information, and by duplication, heredity is believed Breath passes to the next generation, instructs the synthesis of protein to express the hereditary information entrained by oneself, to control bion Trait expression.Genetic test is the technology detected by blood, other body fluid or cell to gene, is to take detected person Peripheric venous blood or other histocytes, after expanding its gene information, by particular device to the gene in detected person's cell Molecular information detects, and analyzes gene type contained by it and gene defect and its a kind of whether normal side of expressive function Method, to allow one to understand the gene information of oneself, specify the cause of disease or predict the risk that body suffers from certain disease.
Gene sequencing technology measures the technology of gene order.In molecular biology research, the sequence analysis of gene is The further basis of research and transformation target gene.Technology currently used for sequencing mainly has the double de- of 1977 invention such as Sanger The chemical degradation method of oxygen chain end cessation method and Maxam and Gilbert1977 invention.Difference is very in principle for both of these approaches Greatly, but all it is that point according to nucleotide in a certain fixation starts, is terminated at some specific base at random, generates A, T, A series of nucleotide of tetra- groups of different lengths of C, G, then electrophoresis is detected in urea-denatured PAGE glue, to obtain base Because of sequence.Present gene sequencing is needed using gene tester, and gene sequencer is all stationarily connected to gene survey with turntable On sequence instrument, the replacement that can not easily carry out, the gene sequencing made work because will be minimum in gene sequencer sky Genetic chip is placed in interior arrangement causes gene sequencing working efficiency low.
Based on this, the present invention devises specially a kind of gene sequencer turntable being convenient for changing, to solve above-mentioned ask Topic.
Summary of the invention
The purpose of the present invention is to provide a kind of gene sequencer turntables being convenient for changing, to solve above-mentioned background technique The problem of middle proposition.
To achieve the above object, the invention provides the following technical scheme: a kind of gene sequencer turntable being convenient for changing, Including support rod, annular groove, pressing device, pressing plate, the first bolt, casing, connecting rod, bracket, sliding slot, groove, bearing, gene Chip placing frame, sliding block, convex block, spring, genetic chip placing groove and the second bolt, upper end is fixedly connected in the support rod Bearing, the Bearing outer are fixedly connected with casing, and gripping mechanism, the gripping mechanism are symmetrically threaded in described sleeve pipe Including pressing plate and the first bolt, first bolt is connect with press plate rotary, and annular is equipped between described sleeve pipe and bearing outer wall Slot, the support rod top are equipped with connecting rod, and the connecting rod bottom is injected in annular groove, uniformly fixed in the connecting rod to connect It is connected to bracket, offers sliding slot on the bracket on two sidewalls, the bracket opens up fluted, is equipped with base between the bracket Because of chip placing frame, sliding block, genetic chip placing frame two sides are fixedly connected on genetic chip placing frame two sidewalls Wall offers translot below sliding block one end, is fixedly connected with bullet in the translot that the genetic chip placing frame opens up Spring, the spring other end are fixedly connected with convex block, and genetic chip placing groove is offered in the genetic chip placing frame, described The second bolt is threaded at the right side mandril middle-end of genetic chip placing frame.
Preferably, first bolt is connect with casing threads, and one end of first bolt is equipped with nut, and described first The other end of bolt is equipped with limited post, offers card slot on the pressing plate, the first bolted limited post is in pressing plate Rotation in card slot.
Preferably, the groove is below sliding slot, and the groove is below the input end of sliding slot.
Preferably, the shape of the sliding slot is dovetail shaped, and the shape of the sliding block is dovetail shaped, and the sliding block is in sliding slot Sliding.
Preferably, the groove of the convex block on the genetic chip placing frame and bracket is slidably connected.
Preferably, second bolt both ends are connected separately with limited block and nut.
Compared with prior art, the beneficial effects of the present invention are:
1. the first bolt and pressing plate cooperation by the way that annular groove is injected in connecting rod bottom in the present invention, while in pressing device, So that device is convenient for changing entire turntable, while the first bolt pusher pressing plate is external by connecting rod bottom and bearing after replacement Fitting is stablized, and turntable is facilitated to rotate, and helps to carry out gene sequencing.
2. the present invention is equipped on the side wall of genetic chip placing frame side and slides by opening up sliding slot and groove on bracket Block and convex block so that device is convenient for changing genetic chip placing frame, while can fix genetic chip placing frame, facilitate into Row gene sequencing.
3. the present invention increases by the second bolt in genetic chip placing frame, so that can be by gene core when device progress gene sequencing Piece fixes, and genetic chip will not move when rotating turntable, facilitates carry out gene sequencing.
Detailed description of the invention
In order to illustrate the technical solution of the embodiments of the present invention more clearly, will be described below to embodiment required Attached drawing is briefly described, it should be apparent that, drawings in the following description are only some embodiments of the invention, for ability For the those of ordinary skill of domain, without creative efforts, it can also be obtained according to these attached drawings other attached Figure.
Fig. 1 is schematic structural view of the invention;
Fig. 2 is genetic chip placing frame of the present invention and its connection structure cross-sectional view;
Fig. 3 is genetic chip placing frame structural schematic diagram of the present invention;
Fig. 4 is convex block of the present invention and its attachment structure schematic diagram;
Fig. 5 is pressing device structural schematic diagram of the present invention;
In attached drawing, parts list represented by the reference numerals are as follows: 1. support rods;2. annular groove;3. pressing device;31. pressing plate; 32. the first bolt;4. casing;5. connecting rod;6. bracket;7. sliding slot;8. groove;9. bearing;10. genetic chip placing frame;11. Sliding block;12. convex block;13. spring;14. genetic chip placing groove;15. the second bolt.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts all other Embodiment shall fall within the protection scope of the present invention.
Embodiment 1
Fig. 1-5 is please referred to, the present invention provides a kind of technical solution: a kind of gene sequencer turntable being convenient for changing, including branch Strut 11, annular groove 2, pressing device 3, pressing plate 31, the first bolt 32, casing 4, connecting rod 5, bracket 6, sliding slot 7, groove 8, axis Hold 9, genetic chip placing frame 10, sliding block 11, convex block 12, spring 13, genetic chip placing groove 14 and the second bolt 15, support rod Upper end is fixedly connected with bearing 9 in 1, and casing 4 is fixedly connected with outside bearing 9, and bearing 9 rotates, and entire turntable is then driven to turn It is dynamic, gripping mechanism 3 is symmetrically threaded on casing 4, gripping mechanism 3 includes pressing plate 31 and the first bolt 32, the first bolt 32 It is rotatablely connected with pressing plate 31, annular groove 2 is equipped between 9 outer wall of casing 4 and bearing, connecting rod 5, connection are equipped with above support rod 1 5 bottom of bar is injected in annular groove 2, and the first bolt 32 and pressing plate 31 in pressing device 3 cooperate, so that device is convenient for changing entirely Turntable, at the same after turntable is replaced the first bolt 32 push pressing plate 31 by 5 bottom of connecting rod with bearing 9 is external is bonded stabilization, Facilitate turntable to rotate, helps to carry out gene sequencing;Bracket 6 is uniformly fixedly connected in connecting rod 5, on bracket 6 on two sidewalls Sliding slot 7 is offered, bracket 6 opens up fluted 8, and genetic chip placing frame 10, genetic chip placing frame 10 are equipped between bracket 6 Sliding block 11 is fixedly connected on two sidewalls, 10 two sidewalls of genetic chip placing frame offer translot below 11 one end of sliding block, Spring 13,13 other end of spring and the fixed company of convex block 12 are fixedly connected in the translot that genetic chip placing frame 10 opens up It connects, so that device is convenient for changing genetic chip placing frame 10, while genetic chip placing frame 10 can be fixed, help to carry out Gene sequencing;Genetic chip placing groove 14 is offered in genetic chip placing frame 10, genetic chip injects genetic chip placing groove In 14, it is threaded with the second bolt 15 at the right side mandril middle-end of genetic chip placing frame 10, so that device carries out gene survey Genetic chip can be fixed when sequence, genetic chip will not move when rotating turntable, facilitate carry out gene sequencing.
Embodiment 2
A kind of gene sequencer turntable being convenient for changing of the present embodiment, it is similar to Example 1, wherein the difference is that, First bolt 32 is threadedly coupled with casing 4, and one end of the first bolt 32 is equipped with nut, and the other end of the first bolt 32 is equipped with limit Column offers card slot on pressing plate 31, and the limited post of the first bolt 32 connection rotates in the card slot 31 of pressing plate, and the first bolt 32 pushes away Dynamic bottom plate 31, while bottom plate 31 facilitates connecting rod 5 to post with 9 outer wall of bearing without rotation.
Embodiment 3
A kind of gene sequencer turntable being convenient for changing of the present embodiment, it is similar to Example 1, wherein the difference is that, For groove 8 below sliding slot 7, groove 8 facilitates plant produced below the input end of sliding slot 7.
Embodiment 4
A kind of gene sequencer turntable being convenient for changing of the present embodiment, it is similar to Example 1, wherein the difference is that, The shape of sliding slot 7 is dovetail shaped, and the shape of sliding block 11 is dovetail shaped, and sliding block 11 slides in sliding slot 7, facilitates bracket 6 and gene Chip placing frame 10 slides.
Embodiment 5
A kind of gene sequencer turntable being convenient for changing of the present embodiment, it is similar to Example 1, wherein the difference is that, Convex block 12 and the groove 8 of bracket 6 on genetic chip placing frame 10 are slidably connected, and facilitate bracket 6 by genetic chip placing frame 10 Clamping, genetic chip placing frame wobble effects gene sequencing when preventing from rotating.
Embodiment 6
A kind of gene sequencer turntable being convenient for changing of the present embodiment, it is similar to Example 1, wherein the difference is that, Second bolt, 15 both ends are connected separately with limited block and nut, and staff is facilitated to fix genetic chip.
In the description of this specification, the description of reference term " one embodiment ", " example ", " specific example " etc. means Particular features, structures, materials, or characteristics described in conjunction with this embodiment or example are contained at least one implementation of the invention In example or example.In the present specification, schematic expression of the above terms may not refer to the same embodiment or example. Moreover, particular features, structures, materials, or characteristics described can be in any one or more of the embodiments or examples to close Suitable mode combines.
Present invention disclosed above preferred embodiment is only intended to help to illustrate the present invention.There is no detailed for preferred embodiment All details are described, are not limited the invention to the specific embodiments described.Obviously, according to the content of this specification, It can make many modifications and variations.These embodiments are chosen and specifically described to this specification, is in order to better explain the present invention Principle and practical application, so that skilled artisan be enable to better understand and utilize the present invention.The present invention is only It is limited by claims and its full scope and equivalent.

Claims (6)

1. a kind of gene sequencer turntable being convenient for changing, which is characterized in that including support rod (1) (1), annular groove (2), pressure Tight device (3), pressing plate (31), the first bolt (32), casing (4), connecting rod (5), bracket (6), sliding slot (7), groove (8), axis Hold (9), genetic chip placing frame (10), sliding block (11), convex block (12), spring (13), genetic chip placing groove (14) and second Bolt (15), it is characterised in that: upper end is fixedly connected with bearing (9) in the support rod (1), fixed outside the bearing (9) It is connected with casing (4), is symmetrically threaded in described sleeve pipe (4) gripping mechanism (3), the gripping mechanism (3) includes pressing plate (31) it is rotatablely connected with the first bolt (32), first bolt (32) and pressing plate (31), described sleeve pipe (4) and bearing (9) are outside Annular groove (2) are equipped between wall, are equipped with connecting rod (5) above the support rod (1), annular is injected in connecting rod (5) bottom In slot (2), uniformly it is fixedly connected with bracket (6) on the connecting rod (5), offers sliding slot on two sidewalls on the bracket (6) (7), the bracket (6) opens up fluted (8), is equipped with genetic chip placing frame (10), the gene between the bracket (6) It is fixedly connected with sliding block (11) on chip placing frame (10) two sidewalls, genetic chip placing frame (10) two sidewalls are in sliding block (11) translot is offered at the lower section of one end, is fixedly connected with spring in the translot that the genetic chip placing frame (10) opens up (13), spring (13) other end is fixedly connected with convex block (12), offers gene in the genetic chip placing frame (10) Chip placing groove (14) is threaded with the second bolt (15) at the right side mandril middle-end of the genetic chip placing frame (10).
2. the gene sequencer turntable according to claim 1 being convenient for changing, which is characterized in that first bolt (32) it is threadedly coupled with casing (4), one end of first bolt (32) is equipped with nut, the other end of first bolt (32) Equipped with limited post, card slot, card slot of the limited post that first bolt (32) connects in pressing plate are offered on the pressing plate (31) (31) rotation in.
3. the gene sequencer turntable according to claim 1 being convenient for changing, which is characterized in that the groove (8) exists Below sliding slot (7), the groove (8) is below the input end of sliding slot (7).
4. the gene sequencer turntable according to claim 1 being convenient for changing, which is characterized in that the sliding slot (7) Shape is dovetail shaped, and the shape of the sliding block (11) is dovetail shaped, the sliding block (11) sliding in sliding slot (7).
5. the gene sequencer turntable according to claim 1 being convenient for changing, which is characterized in that the genetic chip is put The convex block (12) and the groove (8) of bracket (6) set on frame (10) are slidably connected.
6. the gene sequencer turntable according to claim 1 being convenient for changing, which is characterized in that second bolt (15) both ends are connected separately with limited block and nut.
CN201810347499.1A 2018-04-18 2018-04-18 A kind of gene sequencer turntable being convenient for changing Withdrawn CN110157606A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810347499.1A CN110157606A (en) 2018-04-18 2018-04-18 A kind of gene sequencer turntable being convenient for changing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810347499.1A CN110157606A (en) 2018-04-18 2018-04-18 A kind of gene sequencer turntable being convenient for changing

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CN110157606A true CN110157606A (en) 2019-08-23

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111575147A (en) * 2020-04-21 2020-08-25 通用生物系统(安徽)有限公司 Gene sequencer and application method thereof
CN114806971A (en) * 2022-06-08 2022-07-29 广州微立旺生物科技有限公司 Cultivating process based on sulfide bacteria

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111575147A (en) * 2020-04-21 2020-08-25 通用生物系统(安徽)有限公司 Gene sequencer and application method thereof
CN114806971A (en) * 2022-06-08 2022-07-29 广州微立旺生物科技有限公司 Cultivating process based on sulfide bacteria

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Application publication date: 20190823

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