CN110152190A - Electrical brain stimulation method, apparatus, system and terminal device, storage medium - Google Patents
Electrical brain stimulation method, apparatus, system and terminal device, storage medium Download PDFInfo
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- CN110152190A CN110152190A CN201910273050.XA CN201910273050A CN110152190A CN 110152190 A CN110152190 A CN 110152190A CN 201910273050 A CN201910273050 A CN 201910273050A CN 110152190 A CN110152190 A CN 110152190A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
- A61B5/377—Electroencephalography [EEG] using evoked responses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
- A61N1/36031—Control systems using physiological parameters for adjustment
Abstract
The embodiment of the present application is suitable for brain electro-technical field, and disclosing a kind of electrical brain stimulation method, apparatus, system and terminal device, computer readable storage medium, method includes: acquisition brain wave；Brain wave is respectively matched with each predetermined waveform at least one pre-stored stimulation protocol when waveform is swung in forebrain electroshock, judge whether there is and works as forebrain electroshock and swings the target predetermined waveform that waveform is consistent；When judging that next brain electroshock swings whether waveform is consistent with target predetermined waveform there are target predetermined waveform；When waveform is swung in next brain electroshock to be consistent with target predetermined waveform, based on the default stimulation target spot in the corresponding stimulation protocol of target predetermined waveform, the stimulation target spot time is calculated；The stimulation target spot time is subtracted into default stimulation delay time, obtains the goal stimulus time；According to goal stimulus time and the corresponding stimulation protocol of target predetermined waveform, stimulation applications are executed.The real-time of electrical brain stimulation can be improved in the embodiment of the present application.
Description
Technical field
The application belong to brain electro-technical field more particularly to a kind of electrical brain stimulation method, apparatus, system and terminal device,
Computer readable storage medium.
Background technique
With being constantly progressive for brain power technology, contacted between brain wave and the physiological health of people also increasingly closer.
Currently, enhancing brain wave can be played so that user's brain wave synchronizes concussion by rhythmicity environmental stimuli
Amplitude extends the effects of shaking duration with frequency brain wave, and then influences the physiological health of people, for example, making one sleepy, reinforcing depth
Sleep, wake-up, excitement etc..In the existing stage, the synchronous stimulating course of brain electricity is usually to acquire EEG signals, then according to EEG signals
Determine acquired stimulus intensity, time etc..In this process, physics acquisition, analog signal processing, the digital-to-analogue conversion, number of brain electricity
Word signal is packaged, transmission, unpacks, filtering, being required to expend the regular hour using processes such as processing, leads to the synchronous reality stimulated
When property is poor.In addition, stimulation protocol may be because of the loading and control delay of computer system, also to the real-time of the synchronous stimulation of brain electricity
Property has a certain impact.To sum up, the real-time of existing electrical brain stimulation method is poor.
Summary of the invention
In view of this, the embodiment of the present application provides a kind of electrical brain stimulation method, apparatus, system and terminal device, computer
Readable storage medium storing program for executing, to solve the problems, such as that existing electrical brain stimulation method real-time is poor.
The first aspect of the embodiment of the present application provides a kind of electrical brain stimulation method, comprising:
Obtain brain wave；
By the brain wave when forebrain electroshock swing waveform respectively with it is each at least one pre-stored stimulation protocol
Predetermined waveform is matched, and is judged whether there is and is swung the target predetermined waveform that waveform is consistent when forebrain electroshock with described；
The target predetermined waveform that waveform is consistent is swung when forebrain electroshock with described when existing, and judges that next brain electroshock is swung
Whether waveform is consistent with the target predetermined waveform；
When waveform is swung in next brain electroshock to be consistent with the target predetermined waveform, it is based on the target predetermined waveform
Default stimulation target spot in corresponding stimulation protocol calculates the stimulation target spot time；
The stimulation target spot time is subtracted into default stimulation delay time, obtains the goal stimulus time；
According to the goal stimulus time and the corresponding stimulation protocol of the target predetermined waveform, stimulation applications are executed.
With reference to first aspect, in a kind of feasible implementation, described according to the goal stimulus time and described
The corresponding stimulation protocol of target predetermined waveform, execute stimulation applications after, further includes:
Based on the brain wave obtained after stimulation applications, effect of stimulation thorn whether corresponding with the target predetermined waveform is judged
The default effect of stimulation swashed in scheme is consistent；
When the effect of stimulation is consistent with the default effect of stimulation, it is corresponding to repeat the target predetermined waveform
Stimulation protocol；
When the effect of stimulation is not consistent with the default effect of stimulation, it is corresponding to stop the execution target predetermined waveform
Stimulation protocol, and the step of returning to the acquisition brain wave.
With reference to first aspect, described according to the goal stimulus time and the mesh in a kind of feasible implementation
The corresponding stimulation protocol of predetermined waveform is marked, stimulation applications are executed, comprising:
According to the default stimulation means in the corresponding stimulation protocol of the target predetermined waveform, default stimulation parameter and described
Default stimulation target spot, executes equipment to stimulation applications in the goal stimulus time and sends control instruction, so that the stimulation
Operation executes equipment and exports stimulus signal according to the control instruction.
With reference to first aspect, in a kind of feasible implementation, further includes:
Obtain the stimulation protocol additions and deletions information of cloud transmission；
According to the stimulation protocol additions and deletions information, corresponding additions and deletions operation is executed.
With reference to first aspect, in a kind of feasible implementation, described according to the goal stimulus time and described
The corresponding stimulation protocol of target predetermined waveform, execute stimulation applications after, further includes:
Record the relevant information of electrical brain stimulation process；
The relevant information is uploaded to cloud, so that the cloud is according to the relevant information, optimization described at least one
Parameter in a stimulation protocol.
The second aspect of the embodiment of the present application provides a kind of electrical brain stimulation device, comprising:
Module is obtained, for obtaining brain wave；
First judgment module, for by the brain wave when forebrain electroshock swings waveform respectively with pre-stored at least one
Each predetermined waveform in a stimulation protocol is matched, and is judged whether there is and is swung the target that waveform is consistent when forebrain electroshock with described
Predetermined waveform；
Second judgment module swings the target predetermined waveform that waveform is consistent when forebrain electroshock with described for working as to exist,
Judge that next brain electroshock swings whether waveform is consistent with the target predetermined waveform；
First computing module, for when next brain electroshock swings waveform and is consistent with the target predetermined waveform, base
Default stimulation target spot in the corresponding stimulation protocol of the target predetermined waveform calculates the stimulation target spot time；
Second computing module obtains goal stimulus for the stimulation target spot time to be subtracted default stimulation delay time
Time；
Stimulating module, for holding according to the goal stimulus time and the corresponding stimulation protocol of the target predetermined waveform
Row stimulation applications.
The third aspect of the embodiment of the present application provides a kind of electrical brain stimulation system, including electroencephalogramsignal signal collection equipment and institute
The terminal device for stating electroencephalogramsignal signal collection equipment communication connection, the stimulation applications connecting with terminal equipment in communication execution are set
It is standby；
The terminal device is for obtaining brain wave；By the brain wave when forebrain electroshock swing waveform respectively in advance deposit
Each predetermined waveform at least one stimulation protocol of storage is matched, and is judged whether there is with described when waveform is swung in forebrain electroshock
The target predetermined waveform being consistent；The target predetermined waveform that waveform is consistent is swung when forebrain electroshock with described when existing, under judgement
One brain electroshock swings whether waveform is consistent with the target predetermined waveform；When waveform and the target are swung in next brain electroshock
When predetermined waveform is consistent, based on the default stimulation target spot in the corresponding stimulation protocol of the target predetermined waveform, stimulation target is calculated
The point time；The stimulation target spot time is subtracted into default stimulation delay time, obtains the goal stimulus time；It is pierced according to the target
Swash time and the corresponding stimulation protocol of the target predetermined waveform, executes stimulation applications.
In conjunction with the third aspect, in a kind of feasible implementation, further includes being connect with the terminal equipment in communication, be used for
Based on the relevant information of history electrical brain stimulation process, optimize the cloud of the parameter of at least one stimulation protocol.
The fourth aspect of the embodiment of the present application provides a kind of terminal device, including memory, processor and is stored in institute
The computer program that can be run in memory and on the processor is stated, the processor executes real when the computer program
Now such as the step of any one of above-mentioned first aspect the method.
5th aspect of the embodiment of the present application provides a kind of computer readable storage medium, the computer-readable storage medium
Matter is stored with computer program, and the side as described in above-mentioned any one of first aspect is realized when the computer program is executed by processor
The step of method.
Existing beneficial effect is the embodiment of the present application compared with prior art:
The embodiment of the present application swings waveform and the target predetermined waveform in default stimulation protocol by working as forebrain electroshock in judgement
Match, and next brain electroshock swings waveform and is still consistent with target predetermined waveform, then predicts that next one brain electroshock swings waveform still
It is same waveform, then according to the corresponding stimulation protocol of target predetermined waveform and default stimulation delay time, executes in advance
Stimulation applications stimulate delay caused by avoiding because of factors such as data processings so that stimulus signal and stimulation object are completely coincident,
Improve the real-time of the synchronous stimulation of brain electricity.
Detailed description of the invention
It in order to more clearly explain the technical solutions in the embodiments of the present application, below will be to embodiment or description of the prior art
Needed in attached drawing be briefly described, it should be apparent that, the accompanying drawings in the following description is only some of the application
Embodiment for those of ordinary skill in the art without any creative labor, can also be according to these
Attached drawing obtains other attached drawings.
Fig. 1 is a kind of framework schematic block diagram of electrical brain stimulation system provided by the embodiments of the present application；
Fig. 2 is a kind of schematic process flow diagram of electrical brain stimulation method provided by the embodiments of the present application；
Fig. 3 is a kind of structural schematic block diagram of electrical brain stimulation device provided by the embodiments of the present application；
Fig. 4 is the schematic diagram of terminal device provided by the embodiments of the present application.
Specific embodiment
In being described below, for illustration and not for limitation, the tool of such as particular system structure, technology etc is proposed
Body details, so as to provide a thorough understanding of the present application embodiment.However, it will be clear to one skilled in the art that there is no these specific
The application also may be implemented in the other embodiments of details.In other situations, it omits to well-known system, device, electricity
The detailed description of road and method, so as not to obscure the description of the present application with unnecessary details.
In order to illustrate technical solution described herein, the following is a description of specific embodiments.
Embodiment one
It referring to Figure 1, is a kind of framework schematic block diagram of electrical brain stimulation system provided by the embodiments of the present application, which can
To include electroencephalogramsignal signal collection equipment 11, terminal device 12 and and terminal device with electroencephalogramsignal signal collection equipment communication connection
The stimulation applications of communication connection execute equipment 13；In some embodiments, which can also include connecting with terminal equipment in communication
The cloud 14 connect.
Wherein, electroencephalogramsignal signal collection equipment can acquire eeg signal, and eeg signal collected is transmitted to
Terminal device.The specific outer now form of the electroencephalogramsignal signal collection equipment can be arbitrary, as long as it is able to achieve brain wave acquisition, reality
When the transmission functions such as EEG signals.For example, the electroencephalogramsignal signal collection equipment can be wearable brain wave acquisition equipment.
Terminal device is computer terminal under normal circumstances, it is of course also possible to be other kinds of terminal, for example, mobile phone, flat
Plate etc..The terminal device can receive the brain wave of brain wave acquisition equipment transmission；Waveform point is swung into the forebrain electroshock of working as of brain wave
It is not matched with each predetermined waveform at least one pre-stored stimulation protocol, judged whether there is and works as forebrain electroshock
Swing the target predetermined waveform that waveform is consistent；The target predetermined waveform that waveform is consistent is swung when existing and working as forebrain electroshock, is judged next
A brain electroshock swings whether waveform is consistent with target predetermined waveform；Waveform is swung when next brain electroshock to be consistent with target predetermined waveform
When, based on the default stimulation target spot in the corresponding stimulation protocol of target predetermined waveform, calculate the stimulation target spot time；Target spot will be stimulated
Time subtracts default stimulation delay time, obtains the goal stimulus time；It is corresponding according to goal stimulus time and target predetermined waveform
Stimulation protocol, execute stimulation applications.
Optionally, which can also operate according to the additions and deletions of user, correspondingly increase or delete stimulation protocol；?
After carrying out stimulation applications, post-stimulatory EEG signals are based on, judge whether effect of stimulation can achieve the desired results, according to stimulation
Effect determination is to repeat the stimulation protocol, is also off and executes the stimulation protocol；Record relevant information in stimulating course, example
Such as, the stimulation target spot in stimulation protocol, effect of stimulation, stimulation means etc., and these relevant informations are uploaded to cloud server,
So that cloud server carries out big data analysis, optimized with the parameter to stimulation protocol.
Stimulation applications execute equipment and refer to for the control instruction according to terminal device, correspondingly export stimulus signal effect
In the equipment of user.According to the difference of stimulation means, which executes equipment also can be correspondingly different, wherein stimulation hand
Section can any one in specific sonic stimulation, electro photoluminescence, Neural stem cell etc..Cloud may include one or more cloud services
Device can be used for the relevant information based on history electrical brain stimulation process, optimize the parameter of at least one stimulation protocol, and cloud may be used also
To realize the functions such as data storage, stimulation protocol additions and deletions.
Wherein, cloud can receive the relevant information of each electrical brain stimulation, which can pierce for example including brain electricity
Swash scheme, brain wave patterns, post-stimulatory brain wave patterns etc..After collecting a large amount of electrical brain stimulation related data, it can be based on
Big data analysis optimizes reinforcement to the parameter in each stimulation protocol.For example, in order to improve effect of stimulation, by counting greatly
According to analysis, determine that the target position in some stimulation protocol is in advance or to delay, stimulus intensity is to increase or weaken, and is preset
Delay time is to increase or reduce etc., so that when stimulus intensity in stimulation protocol, stimulation target spot information, pre-set delay
Between equal relevant parameters optimized, to improve effect of stimulation.
Certainly, cloud is also based on mass data collected, automatically generates stimulation protocol template, that is, automatically determines thorn
Swash the relevant parameter in scheme, test is then compared by history stimulus data corresponding with each stimulation protocol, automatically
The relevant parameter in stimulation protocol generated is adjusted, determines the corresponding effect of stimulation of stimulation protocol generated.
The application scenarios of electrical brain stimulation system and method provided by the embodiments of the present application can be sleep scene, that is, pass through root
According to the different phase of sleep, additional same frequency stimulus signal, so that brain wave concussion synchronous with additional stimulus signal, to play tune
Section sleep allows people to fall asleep, reinforces the effects of deep sleep；It is of course also possible to be applied to other electrical brain stimulation scenes, do not make herein
It limits.
As it can be seen that passing through the electrical brain stimulation system of the embodiment of the present application, the real-time of electrical brain stimulation can be effectively improved.
Embodiment two
After having introduced the system architecture of the embodiment of the present application, below by from terminal equipment side to electrical brain stimulation method
Related procedure is described explanation.
Fig. 2 is referred to, is a kind of schematic process flow diagram of electrical brain stimulation method provided by the embodiments of the present application, this method can
With the following steps are included:
Step S201, brain wave is obtained.
Step S202, the forebrain electroshock of working as of brain wave is swung into waveform respectively and at least one pre-stored stimulation protocol
Each predetermined waveform matched, judge whether there is with when the target predetermined waveform that waveform is consistent is swung in forebrain electroshock.Work as presence
The target predetermined waveform that waveform is consistent is swung with forebrain electroshock is worked as, enters step S203, conversely, when being not present in swinging when forebrain electroshock
When the target predetermined waveform that waveform is consistent, then return step S202.
It is to be appreciated that above-mentioned stimulation protocol includes but is not limited to predetermined waveform, stimulation target spot information, stimulation means, stimulation
The information such as parameter and effect of stimulation.Predetermined waveform may include the letter such as number that brain wave frequency, wave amplitude and default wave occur
Breath, presetting the number that wave occurs can be for example the number of the α wave appearance in the concussion waveform.Stimulation target spot information may include
Phase (positive wave, negative wave, up and down etc.), angle etc. can be learnt in the stimulation protocol by the stimulation target spot information and be preset
The corresponding stimulation target position of waveform.Stimulation means can be specially but be not limited to sonic stimulation, electro photoluminescence, one in Neural stem cell
Kind, stimulation means are different, and stimulus signal and stimulation applications execution equipment may be different.Stimulation parameter may include but not
It is limited to the information such as stimulus duration, stimulus intensity and pre-set delay amount, pre-set delay amount refers to predetermined time delay, this, which is preset, prolongs
The slow time can be the hardware for being in advance based on each system, by measuring and calculation to each system corresponding delay time.Thorn
Sharp effect refers to corresponding desired effect after each stimulation protocol of execution, for example, the enhancing of concussion energy, same frequency are shaken number and increased
Mostly etc..
Wherein, the predetermined waveform in each stimulation protocol is possibly different from, by by collected brain wave work as
Forebrain electroshock, which is swung waveform and compared one by one with the predetermined waveform in each stimulation protocol respectively, to be matched, judge whether it is consistent, when
Judge then to predict that brain electroshock next time swings waveform and also can when forebrain electroshock swings waveform and is consistent with some target predetermined waveform
It is consistent with the predetermined waveform, whether in order to verify prediction accurately, then needs further to judge whether next brain electroshock swings waveform
It is consistent with target predetermined waveform.
Step S203, judge that next brain electroshock swings whether waveform is consistent with target predetermined waveform.When next brain electroshock
When swinging waveform and being consistent with target predetermined waveform, S204 is entered step, conversely, when next brain electroshock swings waveform and target presets wave
When shape is not consistent, then return step S202.
It is to be appreciated that when next brain electroshock swing waveform be also consistent with target predetermined waveform and when, system then thinks to predict
Correctly, then it predicts that next one waveform is still consistent with the target predetermined waveform, therefore uses the target predetermined waveform corresponding
Stimulation protocol is stimulated.
Step S204, based on the default stimulation target spot in the corresponding stimulation protocol of target predetermined waveform, stimulation target spot is calculated
Time.
It is appreciated that corresponding default stimulation target position can be learnt by stimulation protocol, due to predicting next one brain
Electroshock swings waveform and is still consistent with target predetermined waveform, is equivalent to the next brain wave patterns learnt in current time backward, base
In default stimulation target position, the time in the corresponding target position of next brain wave patterns is calculated, which is to stimulate
The target spot time.
Step S205, the stimulation target spot time is subtracted into default stimulation delay time, obtains the goal stimulus time.
It is to be appreciated that since the processes such as data processing, scheme loading need to expend certain time, if until stimulation target spot
Time is executing stimulation applications, can cause stimulus signal active position more past than default stimulation target position due to stimulation delay
Afterwards, stimulus signal cannot be completely coincident with stimulation target spot, and real-time is poor.In order to enable stimulus signal position and default stimulation
Target spot is completely coincident, and improves the real-time of electrical brain stimulation, system can shift to an earlier date certain time and execute stimulation applications, accordingly even when being
System has certain delay it is also possible that stimulation and prediction object are completely coincident.
Above-mentioned default stimulation delay time, which can be, to be precomputed, and is stored in corresponding stimulation protocol.Generally
In the case of, for every set system due to the difference of the factors such as hardware, corresponding default stimulation delay time all can be different.
Step S206, according to goal stimulus time and the corresponding stimulation protocol of target predetermined waveform, stimulation applications are executed.
Based on parameters such as stimulation means, stimulus intensity, times in stimulation protocol, stimulation is acted and executes time advance extremely
The goal stimulus time, in this way after default stimulation delay time, stimulus signal acts on the time of user and presets stimulation
The target spot time is overlapped, and real-time is higher.Terminal device generates control instruction, by this according to the parameter in corresponding stimulation protocol
Control instruction is sent to stimulation applications and executes equipment, so that stimulation applications execution equipment is corresponding strong according to control instruction generation
The stimulus signal of degree continuingly acts on the brain localization of user.
In some embodiments, above-mentioned according to goal stimulus time and the corresponding stimulation protocol of target predetermined waveform, it executes
The detailed process of stimulation applications may include: according to the default stimulation means, pre- in the corresponding stimulation protocol of target predetermined waveform
If stimulation parameter and default stimulation target spot, execute equipment to stimulation applications in the goal stimulus time and send control instruction, so that
Stimulation applications execute equipment and export stimulus signal according to control instruction.
For example, terminal device can determine voltage swing or electric current according to stimulus intensity when the means of stimulation are Neural stem cell
Size generates control instruction then in conjunction with stimulation target spot information, and the control instruction is sent to stimulation applications and executes equipment, this
When, it may include electromagnetic coil that stimulation applications, which execute equipment, to generate the magnetic of respective strengths by applying external voltage or electric current
?.Stimulation applications execute equipment according to voltage swing or size of current, generate the magnetic field of respective strengths, and based on stimulus duration,
Information, the output phasies such as stimulation target spot answer magnetic field signal to act on user's head position.
After executing stimulation applications, effect of stimulation can be learnt based on post-stimulatory brain wave.Therefore in some embodiments
In, it, can be with after executing stimulation applications above-mentioned according to goal stimulus time and the corresponding stimulation protocol of target predetermined waveform
The following steps are included: judging whether effect of stimulation is corresponding with target predetermined waveform based on the brain wave obtained after stimulation applications
Default effect of stimulation in stimulation protocol is consistent；When effect of stimulation is consistent with default effect of stimulation, it is default to repeat target
The corresponding stimulation protocol of waveform；When effect of stimulation is not consistent with default effect of stimulation, it is corresponding to stop performance objective predetermined waveform
Stimulation protocol, and return obtain brain wave the step of.
Specifically, the brain wave in post-stimulatory certain period of time is analyzed, by judging brain wave whether still
Meet above-mentioned target predetermined waveform, perhaps meet the predetermined waveform in other stimulation protocols or judges the concussion energy of brain wave
Whether whether amount enhance, increase with frequency concussion number, to obtain the corresponding effect of stimulation of stimulation applications.By the effect of stimulation and thorn
Swash corresponding effect of stimulation in scheme to be compared, if be consistent, i.e. the enhancing of brain electricity shock range or same frequency concussion number increases,
Also or post-stimulatory brain wave patterns still conform to target predetermined waveform, then illustrate that the effect of stimulation applications is preferable, can repeat
Execute corresponding stimulation protocol；, whereas if not being consistent, then it can stop executing the stimulation protocol currently executed, lay equal stress on
Newly brain wave is analyzed, is stimulated next time with pending.
One or more stimulation protocols are stored in terminal device, each stimulation protocol corresponds to different wave, different target spots
Stimulation.In some cases, the stimulation protocol in terminal device is fixed, and not can increase can not delete.But one
In a little embodiments, the stimulation protocol in terminal device can be increased and decreased by way of internet, i.e., by terminal device and
Cloud carries out data interaction, operation is increased and decreased to the stimulation protocol in terminal device by cloud, so that flexibility increases
Add.Therefore the above method can be the following steps are included: obtain the stimulation protocol additions and deletions information of cloud transmission；Increased according to stimulation protocol
Information is deleted, corresponding additions and deletions operation is executed.
It is to be appreciated that above-mentioned stimulation protocol additions and deletions information may include needing the information for the stimulation protocol deleted or needing to increase
The information of the stimulation protocol added further includes needing increased stimulation protocol in increasing operation.The stimulation protocol additions and deletions information can
It is inputted with being user by the interactive interface that server-side provides.When if it is delete operation, terminal device can be based on additions and deletions
Information searching is deleted from memory to corresponding stimulation protocol, and by it.It is operated if it is increasing, by the received newly-increased thorn of institute
Sharp scheme is stored in memory, and records the relevant information of the newly-increased scheme.
In some embodiments, terminal device can recorde the relevant information of each electrical brain stimulation, and will be in relevant information
Cloud is reached, so that cloud is based on the relevant information, parameter optimization is carried out to stimulation protocol automatically.Therefore it is pierced above-mentioned according to target
Swash time and the corresponding stimulation protocol of target predetermined waveform, can also include: record electrical brain stimulation mistake after executing stimulation applications
The relevant information of journey；Relevant information is uploaded to cloud, so that cloud according to relevant information, optimizes at least one stimulation protocol
Parameter.
Wherein, cloud can receive the relevant information of each electrical brain stimulation, which can pierce for example including brain electricity
Swash scheme, brain wave patterns and post-stimulatory brain wave patterns etc..It, can be with base after collecting a large amount of electrical brain stimulation related data
In big data analysis, reinforcement is optimized to the parameter in each stimulation protocol.For example, in order to improve effect of stimulation, by big
Data analysis, determines that the target position in some stimulation protocol is in advance or to delay, and stimulus intensity is to increase or weaken, in advance
If delay time is to increase or reduce etc., so that stimulus intensity, stimulation target spot information, pre-set delay in stimulation protocol
The relevant parameters such as time are optimized, to improve effect of stimulation.
Certainly, cloud is also based on mass data collected, automatically generates stimulation protocol template, that is, automatically determines thorn
Swash the relevant parameter in scheme, test is then compared by history stimulus data corresponding with each stimulation protocol, automatically
The relevant parameter in stimulation protocol generated is adjusted, determines the corresponding effect of stimulation of stimulation protocol generated.
As it can be seen that the present embodiment swings waveform and the target predetermined waveform in default stimulation protocol by working as forebrain electroshock in judgement
Match, and next brain electroshock swings waveform and is still consistent with target predetermined waveform, then predicts that next one brain electroshock swings waveform still
It is same waveform, then according to the corresponding stimulation protocol of target predetermined waveform and default stimulation delay time, executes in advance
Stimulation applications are based on Waveform forecast and pre-set stimulation protocol, preset in advance stimulates delay time to execute stimulation applications,
So that stimulus signal and stimulation object are completely coincident, delay is stimulated caused by avoiding because of factors such as data processings, improves brain
The real-time of the synchronous stimulation of electricity.
It should be understood that the size of the serial number of each step is not meant that the order of the execution order in above-described embodiment, each process
Execution sequence should be determined by its function and internal logic, the implementation process without coping with the embodiment of the present application constitutes any limit
It is fixed.
Embodiment three
Fig. 3 is referred to, is a kind of structural schematic block diagram of electrical brain stimulation device provided by the embodiments of the present application, which can
To include:
Module 31 is obtained, for obtaining brain wave；
First judgment module 32, for by brain wave when forebrain electroshock swing waveform respectively with it is pre-stored at least one
Each predetermined waveform in stimulation protocol is matched, and is judged whether there is and is swung target that waveform is consistent when forebrain electroshock and preset wave
Shape；
Second judgment module 33 swings the target predetermined waveform that waveform is consistent for working as to exist and work as forebrain electroshock, under judgement
One brain electroshock swings whether waveform is consistent with target predetermined waveform；
First computing module 34, for being based on target when next brain electroshock swings waveform and is consistent with target predetermined waveform
Default stimulation target spot in the corresponding stimulation protocol of predetermined waveform calculates the stimulation target spot time；
Second computing module 35, for the target spot time will to be stimulated to subtract default stimulation delay time, when obtaining goal stimulus
Between；
Stimulating module 36, for executing stimulation according to goal stimulus time and the corresponding stimulation protocol of target predetermined waveform
Operation.
In a kind of feasible implementation, above-mentioned apparatus can also include:
Third judgment module, for judging whether effect of stimulation is pre- with target based on the brain wave obtained after stimulation applications
If the default effect of stimulation in the corresponding stimulation protocol of waveform is consistent；
Execution module, it is corresponding for when effect of stimulation is consistent with default effect of stimulation, repeating target predetermined waveform
Stimulation protocol；
Stopping modular, for stopping performance objective predetermined waveform pair when effect of stimulation is not consistent with default effect of stimulation
The stimulation protocol answered, and return to the step of obtaining brain wave.
In a kind of feasible implementation, above-mentioned stimulating module includes:
Control unit, for according to the default stimulation means in the corresponding stimulation protocol of target predetermined waveform, default stimulation
Parameter and default stimulation target spot, execute equipment to stimulation applications in the goal stimulus time and send control instruction, so that stimulation is grasped
Make to execute equipment according to control instruction output stimulus signal.
In a kind of feasible implementation, above-mentioned apparatus can also include:
Additions and deletions data obtaining module, for obtaining the stimulation protocol additions and deletions information of cloud transmission；
Additions and deletions module, for executing corresponding additions and deletions operation according to stimulation protocol additions and deletions information.
In a kind of feasible implementation, above-mentioned apparatus can also include:
Logging modle, for recording the relevant information of electrical brain stimulation process；
Uploading module, for relevant information to be uploaded to cloud, so that cloud according to relevant information, optimizes at least one thorn
Swash the parameter in scheme.
It is to be appreciated that the same or similar place between the present embodiment and above-mentioned each embodiment, can with cross-reference,
This is repeated no more.
As it can be seen that the real-time of electrical brain stimulation can be improved in the present embodiment.
Example IV
Fig. 4 is the schematic diagram for the terminal device that one embodiment of the application provides.As shown in figure 4, the terminal of the embodiment is set
Standby 4 include: processor 40, memory 41 and are stored in the meter that can be run in the memory 41 and on the processor 40
Calculation machine program 42.The processor 40 is realized when executing the computer program 42 in above-mentioned each electrical brain stimulation embodiment of the method
The step of, such as step S201 to S206 shown in Fig. 2.Alternatively, reality when the processor 40 executes the computer program 42
Each module or the function of unit in existing above-mentioned each Installation practice, such as the function of module 31 to 36 shown in Fig. 3.
Illustratively, the computer program 42 can be divided into one or more modules or unit, it is one or
The multiple modules of person or unit are stored in the memory 41, and are executed by the processor 40, to complete the application.It is described
One or more modules or unit can be the series of computation machine program instruction section that can complete specific function, which uses
In implementation procedure of the description computer program 42 in the terminal device 4.For example, the computer program 42 can be by
It is divided into and obtains module, first judgment module, the second judgment module, the first computing module, the second computing module and stimulation mould
Block, each module concrete function are as follows:
Module is obtained, for obtaining brain wave；First judgment module, for waveform point to be swung in the forebrain electroshock of working as of brain wave
It is not matched with each predetermined waveform at least one pre-stored stimulation protocol, judged whether there is and works as forebrain electroshock
Swing the target predetermined waveform that waveform is consistent；Second judgment module exists and for working as when the target that waveform is consistent is swung in forebrain electroshock
Predetermined waveform judges that next brain electroshock swings whether waveform is consistent with target predetermined waveform；First computing module, for when next
When a brain electroshock swings waveform and is consistent with target predetermined waveform, based on the default stimulation in the corresponding stimulation protocol of target predetermined waveform
Target spot calculates the stimulation target spot time；Second computing module is obtained for the target spot time will to be stimulated to subtract default stimulation delay time
To the goal stimulus time；Stimulating module, for executing according to goal stimulus time and the corresponding stimulation protocol of target predetermined waveform
Stimulation applications.
The terminal device 4 can be desktop PC, notebook and palm PC etc. and calculate equipment.The terminal
Equipment may include, but be not limited only to, processor 40, memory 41.It will be understood by those skilled in the art that Fig. 4 is only terminal
The example of equipment 4 does not constitute the restriction to terminal device 4, may include than illustrating more or fewer components, or combination
Certain components or different components, for example, the terminal device can also include input-output equipment, network access equipment,
Bus etc..
Alleged processor 40 can be central processing unit (Central Processing Unit, CPU), can also be
Other general processors, digital signal processor (Digital Signal Processor, DSP), specific integrated circuit
(Application Specific Integrated Circuit, ASIC), ready-made programmable gate array (Field-
Programmable Gate Array, FPGA) either other programmable logic device, discrete gate or transistor logic,
Discrete hardware components etc..General processor can be microprocessor or the processor is also possible to any conventional processor
Deng.
The memory 41 can be the internal storage unit of the terminal device 4, such as the hard disk or interior of terminal device 4
It deposits.The memory 41 is also possible to the External memory equipment of the terminal device 4, such as be equipped on the terminal device 4
Plug-in type hard disk, intelligent memory card (Smart Media Card, SMC), secure digital (Secure Digital, SD) card dodge
Deposit card (Flash Card) etc..Further, the memory 41 can also both include the storage inside list of the terminal device 4
Member also includes External memory equipment.The memory 41 is for storing needed for the computer program and the terminal device
Other programs and data.The memory 41 can be also used for temporarily storing the data that has exported or will export.
It is apparent to those skilled in the art that for convenience of description and succinctly, only with above-mentioned each function
Can unit, module division progress for example, in practical application, can according to need and by above-mentioned function distribution by different
Functional unit, module are completed, i.e., the internal structure of described device is divided into different functional unit or module, more than completing
The all or part of function of description.Each functional unit in embodiment, module can integrate in one processing unit, can also
To be that each unit physically exists alone, can also be integrated in one unit with two or more units, it is above-mentioned integrated
Unit both can take the form of hardware realization, can also realize in the form of software functional units.In addition, each function list
Member, the specific name of module are also only for convenience of distinguishing each other, the protection scope being not intended to limit this application.Above system
The specific work process of middle unit, module, can refer to corresponding processes in the foregoing method embodiment, and details are not described herein.
In the above-described embodiments, it all emphasizes particularly on different fields to the description of each embodiment, is not described in detail or remembers in some embodiment
The part of load may refer to the associated description of other embodiments.
Those of ordinary skill in the art may be aware that list described in conjunction with the examples disclosed in the embodiments of the present disclosure
Member and algorithm steps can be realized with the combination of electronic hardware or computer software and electronic hardware.These functions are actually
It is implemented in hardware or software, the specific application and design constraint depending on technical solution.Professional technician
Each specific application can be used different methods to achieve the described function, but this realization is it is not considered that exceed
Scope of the present application.
In embodiment provided herein, it should be understood that disclosed device, terminal device and method, it can be with
It realizes by another way.For example, device described above, terminal device embodiment are only schematical, for example, institute
The division of module or unit is stated, only a kind of logical function partition, there may be another division manner in actual implementation, such as
Multiple units or components can be combined or can be integrated into another system, or some features can be ignored or not executed.Separately
A bit, shown or discussed mutual coupling or direct-coupling or communication connection can be through some interfaces, device
Or the INDIRECT COUPLING or communication connection of unit, it can be electrical property, mechanical or other forms.
The unit as illustrated by the separation member may or may not be physically separated, aobvious as unit
The component shown may or may not be physical unit, it can and it is in one place, or may be distributed over multiple
In network unit.It can select some or all of unit therein according to the actual needs to realize the mesh of this embodiment scheme
's.
It, can also be in addition, each functional unit in each embodiment of the application can integrate in one processing unit
It is that each unit physically exists alone, can also be integrated in one unit with two or more units.Above-mentioned integrated list
Member both can take the form of hardware realization, can also realize in the form of software functional units.
If the integrated module or unit are realized in the form of SFU software functional unit and sell as independent product
Or it in use, can store in a computer readable storage medium.Based on this understanding, the application realizes above-mentioned reality
The all or part of the process in a method is applied, relevant hardware can also be instructed to complete by computer program, it is described
Computer program can be stored in a computer readable storage medium, the computer program when being executed by processor, it can be achieved that
The step of above-mentioned each embodiment of the method.Wherein, the computer program includes computer program code, the computer program
Code can be source code form, object identification code form, executable file or certain intermediate forms etc..Computer-readable Jie
Matter may include: can carry the computer program code any entity or device, recording medium, USB flash disk, mobile hard disk,
Magnetic disk, CD, computer storage, read-only memory (ROM, Read-Only Memory), random access memory (RAM,
Random Access Memory), electric carrier signal, telecommunication signal and software distribution medium etc..It should be noted that described
The content that computer-readable medium includes can carry out increasing appropriate according to the requirement made laws in jurisdiction with patent practice
Subtract, such as does not include electric carrier signal and electricity according to legislation and patent practice, computer-readable medium in certain jurisdictions
Believe signal.
Embodiment described above is only to illustrate the technical solution of the application, rather than its limitations；Although referring to aforementioned reality
Example is applied the application is described in detail, those skilled in the art should understand that: it still can be to aforementioned each
Technical solution documented by embodiment is modified or equivalent replacement of some of the technical features；And these are modified
Or replacement, the spirit and scope of each embodiment technical solution of the application that it does not separate the essence of the corresponding technical solution should all
Comprising within the scope of protection of this application.
Claims (10)
1. a kind of electrical brain stimulation method characterized by comprising
Obtain brain wave；
By the brain wave when forebrain electroshock swing waveform respectively with it is each default at least one pre-stored stimulation protocol
Waveform is matched, and is judged whether there is and is swung the target predetermined waveform that waveform is consistent when forebrain electroshock with described；
The target predetermined waveform that waveform is consistent is swung when forebrain electroshock with described when existing, and judges that waveform is swung in next brain electroshock
Whether it is consistent with the target predetermined waveform；
It is corresponding based on the target predetermined waveform when waveform is swung in next brain electroshock to be consistent with the target predetermined waveform
Stimulation protocol in default stimulation target spot, calculate stimulation the target spot time；
The stimulation target spot time is subtracted into default stimulation delay time, obtains the goal stimulus time；
According to the goal stimulus time and the corresponding stimulation protocol of the target predetermined waveform, stimulation applications are executed.
2. the method as described in claim 1, which is characterized in that described pre- according to the goal stimulus time and the target
If the corresponding stimulation protocol of waveform, after execution stimulation applications, further includes:
Based on the brain wave obtained after stimulation applications, effect of stimulation stimulation side whether corresponding with the target predetermined waveform is judged
Default effect of stimulation in case is consistent；
When the effect of stimulation is consistent with the default effect of stimulation, the corresponding stimulation of the target predetermined waveform is repeated
Scheme；
When the effect of stimulation is not consistent with the default effect of stimulation, stop executing the corresponding thorn of the target predetermined waveform
Swash scheme, and the step of returning to the acquisition brain wave.
3. the method as described in claim 1, which is characterized in that described default according to the goal stimulus time and the target
The corresponding stimulation protocol of waveform executes stimulation applications, comprising:
According to the default stimulation means in the corresponding stimulation protocol of the target predetermined waveform, default stimulation parameter and described default
Target spot is stimulated, equipment is executed to stimulation applications in the goal stimulus time and sends control instruction, so that the stimulation applications
It executes equipment and stimulus signal is exported according to the control instruction.
4. the method as described in claim 1, which is characterized in that further include:
Obtain the stimulation protocol additions and deletions information of cloud transmission；
According to the stimulation protocol additions and deletions information, corresponding additions and deletions operation is executed.
5. such as the described in any item methods of Claims 1-4, which is characterized in that it is described according to the goal stimulus time and
The corresponding stimulation protocol of the target predetermined waveform, after executing stimulation applications, further includes:
Record the relevant information of electrical brain stimulation process；
The relevant information is uploaded to cloud, so that the cloud is according to the relevant information, at least one described thorn of optimization
Swash the parameter in scheme.
6. a kind of electrical brain stimulation device characterized by comprising
Module is obtained, for obtaining brain wave；
First judgment module, for by the brain wave when forebrain electroshock swing waveform respectively at least one pre-stored thorn
Each predetermined waveform swashed in scheme is matched, and is judged whether there is with described when to swing target that waveform is consistent default for forebrain electroshock
Waveform；
Second judgment module, for judging when swinging the target predetermined waveform that waveform is consistent when forebrain electroshock in the presence of with described
Next brain electroshock swings whether waveform is consistent with the target predetermined waveform；
First computing module, for being based on institute when next brain electroshock swings waveform and is consistent with the target predetermined waveform
The default stimulation target spot in the corresponding stimulation protocol of target predetermined waveform is stated, the stimulation target spot time is calculated；
Second computing module obtains the goal stimulus time for the stimulation target spot time to be subtracted default stimulation delay time；
Stimulating module, for executing thorn according to the goal stimulus time and the corresponding stimulation protocol of the target predetermined waveform
Swash operation.
7. a kind of electrical brain stimulation system, which is characterized in that including electroencephalogramsignal signal collection equipment and the electroencephalogramsignal signal collection equipment
The terminal device of communication connection, the stimulation applications connecting with the terminal equipment in communication execute equipment；
The terminal device is for obtaining brain wave；By the brain wave when forebrain electroshock swing waveform respectively with it is pre-stored
Each predetermined waveform at least one stimulation protocol is matched, and is judged whether there is and is consistent with described when waveform is swung in forebrain electroshock
Target predetermined waveform；The target predetermined waveform that waveform is consistent is swung when forebrain electroshock with described when existing, and is judged next
Brain electroshock swings whether waveform is consistent with the target predetermined waveform；Waveform is swung when next brain electroshock to preset with the target
When waveform is consistent, based on the default stimulation target spot in the corresponding stimulation protocol of the target predetermined waveform, when calculating stimulation target spot
Between；The stimulation target spot time is subtracted into default stimulation delay time, obtains the goal stimulus time；When according to the goal stimulus
Between stimulation protocol corresponding with the target predetermined waveform, execute stimulation applications.
8. system according to claim 7, which is characterized in that further include being connect with the terminal equipment in communication, be used for base
In the relevant information of history electrical brain stimulation process, optimize the cloud of the parameter of at least one stimulation protocol.
9. a kind of terminal device, which is characterized in that in the memory and can be in institute including memory, processor and storage
The computer program run on processor is stated, the processor realizes such as claim 1 to 5 times when executing the computer program
The step of one the method.
10. a kind of computer readable storage medium, which is characterized in that the computer-readable recording medium storage has computer journey
Sequence is realized when the computer program is executed by processor such as the step of any one of claim 1 to 5 the method.
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