CN110151135A - Long-range stored program controlled with actual conversation analysis - Google Patents

Long-range stored program controlled with actual conversation analysis Download PDF

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Publication number
CN110151135A
CN110151135A CN201910449736.XA CN201910449736A CN110151135A CN 110151135 A CN110151135 A CN 110151135A CN 201910449736 A CN201910449736 A CN 201910449736A CN 110151135 A CN110151135 A CN 110151135A
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CN
China
Prior art keywords
center
patient
imd
data
big
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Pending
Application number
CN201910449736.XA
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Chinese (zh)
Inventor
陈林
陈浩
马伯志
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tsinghua University
Beijing Pins Medical Co Ltd
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Tsinghua University
Beijing Pins Medical Co Ltd
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Publication date
Application filed by Tsinghua University, Beijing Pins Medical Co Ltd filed Critical Tsinghua University
Priority to CN201910449736.XA priority Critical patent/CN110151135A/en
Publication of CN110151135A publication Critical patent/CN110151135A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4803Speech analysis specially adapted for diagnostic purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/74Details of notification to user or communication with user or patient ; user input means
    • A61B5/7465Arrangements for interactive communication between patient and care services, e.g. by using a telephone network
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36067Movement disorders, e.g. tremor or Parkinson disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128Control systems
    • A61N1/36146Control systems specified by the stimulation parameters
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H80/00ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring

Abstract

It include being sequentially connected the invention belongs to technical field of medical equipment more particularly to a kind of long-range stored program controlled with actual conversation analysis: big center, branch center, control equipment, implantable medical device IMD;Branch center is established long-distance video with patient for doctor and is connect, and the patient's language extracted expression data and EEG signals data are sent to big center, doctor decides whether to remotely operate IMD by control equipment according to the suggestion that big center sends over.The patient's language expression data and EEG signals data that big center is extracted according to branch center, to judge patient with the presence or absence of dysarthrosis.IMD includes: battery, chip, sensor, realizes that brain issues frequency conversion electro photoluminescence.The present invention is able to solve the symptom identification problem of dysarthrosis, long-range program-controlled while doing symptomatic diagnosis;The parameter for analyzing and adapting to patient symptom can be expressed by dialog procedure language, and be stored in server, facilitate subsequent doctor that implantation equipment parameters are quickly set.

Description

Long-range stored program controlled with actual conversation analysis
Technical field
The invention belongs to technical field of medical equipment more particularly to a kind of long-range stored program controlleds with actual conversation analysis.
Background technique
Dysarthrosis is the common non-motor symptoms of one kind of disturbances in patients with Parkinson disease, and patient is mainly shown as cacoepy, stings Word is unclear, the change of the speech auditions characteristic such as the sound, tone, speed, allorhythmia and Hypernasality, that is to say, that words are ambiguous not It is cleer and peaceful unfluent.When serious, partial, language do not form a complete sentence speech, it is difficult to understand.It is completely mute even in the worst case, there is structure sound not Energy.But content expressed by disturbances in patients with Parkinson disease speech and grammer be all often it is normal, to understand other people language also without difficulty, And it is only spoken expression obstacle.
In clinic, disturbances in patients with Parkinson disease implantation brain pacemaker its subthalamic nuclei is stimulated, can significantly improve its tremble, The symptoms such as body is stiff.However, being the stimulation of constant frequency to the stimulation of subthalamic nuclei.After prolonged stimulation, part is suffered from Person can generate gait freeze, dysarthrosis, the subsidiary symptom such as unusual fluctuation.In addition, the stimulation of long-time single-frequency, such as 100 hertz, Patient is set to be easy to generate adaptability to this stimulation, similar to patient to the adaptability of drug, effect of stimulation is deteriorated.Face some In bed case, frequency conversion stimulus modality is for treating disturbances in patients with Parkinson disease.It is clinical research shows that frequency conversion electro photoluminescence can improve pa The non-motor symptoms for improving Parkinson while motor symptoms (such as tremble or/and body is stiff) of Jin Sen, if gait is freezed, structure Sound barrier hinders, mobile etc., and can be avoided adaptability caused by constant frequency.
But the development of existing frequency conversion stimulus modality medical procedure is dependent on the doctor having wide experience in particular hospital pair After patient carries out face-to-face condition-inference analysis, the adjustment of operating parameter could be carried out to brain pacemaker.This is not only to doctor Level and experience have high requirement, technical difficulty also is increased to the universal of network remote medical technology, to many patients Medical bring limitation.How to get rid of when the carry out diagnosing and treating to disturbances in patients with Parkinson disease to veteran doctor Dependence, reduce mistake brought by the subjectivity of diagnosis and treatment, really realize network remote medical diagnosis and treatment Disturbances in patients with Parkinson disease is the technical problem for needing to solve.
Summary of the invention
In view of the above technical problems, the invention proposes a kind of long-range stored program controlleds with actual conversation analysis, including according to It is secondary connected: big center, branch center, control equipment, implantable medical device (IMD);Wherein, big center and branch center pass through mutual Networking is connected, and branch center, control equipment, IMD pass sequentially through bluetooth wireless connection;When judge patient there are when dysarthrosis, The suggestion of frequency conversion electro photoluminescence is sent to doctor by big center.
The branch center is established long-distance video with patient for doctor and is connect, and the patient's language extracted is expressed data It is sent to big center with EEG signals data, doctor decides whether according to the suggestion that big center sends over by controlling equipment To be remotely operated to IMD.
The patient's language expression data and EEG signals data that the big center is extracted according to branch center, to judge patient With the presence or absence of dysarthrosis.
The judgement patient includes: that the acoustics of the language expression data in the same period is special with the presence or absence of dysarthrosis Sign is compared with EEG signals data, is occurred if there is language to express relevant EEG signals, and the acoustics of language expression data There is exception in feature, then dysarthrosis occurs in judgement.
The EEG signals data that IMD is extracted are sent branch center by the control equipment, and branch center is sended over Instruction be sent to IMD to realize the remote operation to IMD.
The IMD includes: battery, chip, sensor, realizes that brain issues frequency conversion electro photoluminescence, the remote operation includes Operating status including IMD cell voltage, runing time, power, electric current is adjusted.
The big-and-middle heart includes: parameter recommending module, evaluation module, standard parameter library, records in real time and saves patient just Data and diagnosis and operation data are examined, and tracks later period medical effect feedback data, irregularly optimizes recommended parameter.
The big center is computer.
The branch center is multimedia computer.
The control equipment is bluetooth communication equipment.
Beneficial effects of the present invention: the present invention is able to solve the symptom identification problem of dysarthrosis, it is long-range it is program-controlled simultaneously Do symptomatic diagnosis;The parameter for analyzing and adapting to patient symptom can be expressed by dialog procedure language, and be stored in server, Facilitate subsequent doctor that implantation equipment parameters are quickly set.Patient's different pathogeny, different syndromes situation can easily be set Different operating parameters is set remotely to meet diagnosing and treating.Experiment shows that system of the invention not only causes Parkinson's disease Dysarthrosis, also for Other diseases such as myodystony relevant to movement, and to cognition, the relevant nerve disease of psychology Disease such as depression, habituation, there is good curative effect.
Detailed description of the invention
Fig. 1 is the long-range stored program controlled structural schematic diagram of the invention with actual conversation analysis.
Fig. 2 is the long-range stored program controlled rough schematic view of the invention with actual conversation analysis.
Specific embodiment
With reference to the accompanying drawing, it elaborates to embodiment.
As shown in Figure 1, 2, the invention proposes a kind of long-range stored program controlleds with actual conversation analysis, including are sequentially connected : big center, branch center, control equipment, implantable medical device (IMD);Wherein, big center passes through internet phase with branch center Even, branch center, control equipment, IMD pass sequentially through bluetooth wireless connection;When judge patient there are when dysarthrosis, big center The suggestion of frequency conversion electro photoluminescence is sent to doctor.
The branch center is established long-distance video with patient for doctor and is connect, and the patient's language extracted is expressed data It is sent to big center with EEG signals data, doctor decides whether according to the suggestion that big center sends over by controlling equipment To be remotely operated to IMD.
The patient's language expression data and EEG signals data that the big center is extracted according to branch center, to judge patient With the presence or absence of dysarthrosis.
The judgement patient includes: that the acoustics of the language expression data in the same period is special with the presence or absence of dysarthrosis Sign is compared with EEG signals data, is occurred if there is language to express relevant EEG signals, and the acoustics of language expression data There is exception in feature, then dysarthrosis occurs in judgement.
The EEG signals data that IMD is extracted are sent branch center by the control equipment, and branch center is sended over Instruction be sent to IMD to realize the remote operation to IMD.
The IMD includes: battery, chip, sensor, realizes that brain issues frequency conversion electro photoluminescence, the remote operation includes Operating status including IMD cell voltage, runing time, power, electric current is adjusted.
The big-and-middle heart includes: parameter recommending module, evaluation module, standard parameter library, records in real time and saves patient just Data and diagnosis and operation data are examined, and tracks later period medical effect feedback data, irregularly optimizes recommended parameter.
The big center is computer.
The branch center is multimedia computer.
The control equipment is bluetooth communication equipment.
A kind of working method of long-range stored program controlled with actual conversation analysis of the invention is as follows:
Doctor establishes network video with patient using branch center and connect, and patient's language expression number is extracted by actual conversation According to, and big center is sent together with the EEG signals data that IMD is extracted by patient's language expression data, big center will be same The acoustic feature of language expression data in period is compared with EEG signals data, if there is language to express relevant brain electricity Signal occurs, and the acoustic feature of language expression data occurs abnormal, then dysarthrosis occurs in judgement, and by dysarthric symptom Prompt and program-controlled suggestion be sent to branch center, doctor decides whether to set by control according to the suggestion that big center sends over It is standby that IMD is remotely operated, including being carried out to the operating status including IMD cell voltage, runing time, power, electric current Adjustment.Big-and-middle pericardium includes record in real time and saves patient assessment's data and diagnosis and operation data, and tracks later period medical treatment Staining effect data, irregularly optimize recommended parameter.
This embodiment is merely preferred embodiments of the present invention, but scope of protection of the present invention is not limited thereto, In the technical scope disclosed by the present invention, any changes or substitutions that can be easily thought of by anyone skilled in the art, It should be covered by the protection scope of the present invention.Therefore, protection scope of the present invention should be with scope of protection of the claims Subject to.

Claims (10)

1. a kind of long-range stored program controlled with actual conversation analysis, which is characterized in that including what is be sequentially connected: big center, point in The heart, control equipment, implantable medical device (IMD);Wherein, big center is connected with branch center by internet, branch center, control Equipment, IMD pass sequentially through bluetooth wireless connection;When judging patient there are when dysarthrosis, big center is by frequency conversion electro photoluminescence It is recommended that being sent to doctor.
2. system according to claim 1, which is characterized in that long-distance video company is established for doctor and patient in the branch center It connects, and the patient's language extracted expression data and EEG signals data is sent to big center, doctor sends according to big center The suggestion that comes over decides whether to remotely operate IMD by control equipment.
3. system according to claim 1, which is characterized in that patient's language table that the big center is extracted according to branch center Up to data and EEG signals data, to judge patient with the presence or absence of dysarthrosis.
4. system according to claim 3, which is characterized in that the judgement patient includes: with the presence or absence of dysarthrosis will be same The acoustic feature of language expression data in one period is compared with EEG signals data, if there is language to express relevant brain Electric signal occurs, and exception occurs in the acoustic feature of language expression data, then dysarthrosis occurs in judgement.
5. system according to claim 1, which is characterized in that the EEG signals data that the control equipment extracts IMD It is sent to branch center, and the instruction that branch center is sended over is sent to IMD to realize the remote operation to IMD.
6. system according to claim 1, which is characterized in that the IMD includes: battery, chip, sensor, realizes brain Frequency conversion electro photoluminescence is issued, the remote operation is including to the operating status including IMD cell voltage, runing time, power, electric current It is adjusted.
7. system according to claim 1, which is characterized in that the big-and-middle heart include: parameter recommending module, evaluation module, Standard parameter library records in real time and saves patient assessment's data and diagnosis and operation data, and tracks later period medical effect Feedback data irregularly optimizes recommended parameter.
8. system according to claim 1, which is characterized in that the big center is computer.
9. system according to claim 1, which is characterized in that the branch center is multimedia computer.
10. system according to claim 1, which is characterized in that the control equipment is bluetooth communication equipment.
CN201910449736.XA 2019-05-28 2019-05-28 Long-range stored program controlled with actual conversation analysis Pending CN110151135A (en)

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CN113724687A (en) * 2021-08-30 2021-11-30 深圳市神经科学研究院 Electroencephalogram signal based voice generation method and device, terminal and storage medium
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Application publication date: 20190823

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