CN110143632A - A kind of water for injection cooling system based on how colod-application point - Google Patents
A kind of water for injection cooling system based on how colod-application point Download PDFInfo
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- CN110143632A CN110143632A CN201910552403.XA CN201910552403A CN110143632A CN 110143632 A CN110143632 A CN 110143632A CN 201910552403 A CN201910552403 A CN 201910552403A CN 110143632 A CN110143632 A CN 110143632A
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- water
- colod
- valve
- tube
- branch pipe
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims abstract description 110
- 239000008215 water for injection Substances 0.000 title claims abstract description 77
- 238000001816 cooling Methods 0.000 title claims abstract description 45
- 238000010992 reflux Methods 0.000 claims abstract description 9
- 230000008676 import Effects 0.000 claims description 7
- 238000010276 construction Methods 0.000 abstract description 5
- 230000000813 microbial effect Effects 0.000 abstract description 4
- 239000000243 solution Substances 0.000 description 6
- 238000009826 distribution Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 239000003643 water by type Substances 0.000 description 2
- 238000000151 deposition Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/02—Treatment of water, waste water, or sewage by heating
- C02F1/04—Treatment of water, waste water, or sewage by heating by distillation or evaporation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Hydrology & Water Resources (AREA)
- Engineering & Computer Science (AREA)
- Environmental & Geological Engineering (AREA)
- Water Supply & Treatment (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
Abstract
The invention discloses a kind of water for injection cooling systems based on how colod-application point, belong to water for injection technical field.The water for injection cooling system includes main pipeline and the branch pipe(tube) equipped with the colod-application point of several groups, and the front end and end of the branch pipe(tube) pass through cooling component respectively and the 4th valve is connected with main pipeline；Wherein, several groups are additionally provided on the branch pipe(tube) for preventing the reflux mechanism in branch pipe(tube) there are stagnant water.Water for injection cooling system provided in an embodiment of the present invention can meet use of the colod-application point of multiple groups in workshop to water for injection, simultaneously so as to reduce the construction and operating cost of system.In addition, can guarantee the presence without stagnant water in branch pipe(tube) by selection the 5th valve of switch and the 6th valve, so as to the microbial load of effective control system, to avoid the contaminated risk of water for injection occurs.
Description
Technical field
The present invention relates to water for injection technical field, specifically a kind of water for injection cooling system based on how colod-application point.
Background technique
The 99th article of Chinese new edition GMP to the circulating temperature of water for injection require for " water for injection can be used 70 DEG C with
Upper soak cycles ", because water for injection storage most in the industry and distribution system are all in not less than 70 DEG C or more temperature
Degree carries out soak cycles.
Currently, water for injection storage and distribution system share three parts composition: stocking system, distribution system and with pipe network
Part.Enter stocking system by water for injection prepared by distillation machine, be transported in workshop point pipe network by distribution system,
It is recirculated back to stocking system, is fetched water by opening with point valve in workshop.Wherein, usually using 70 DEG C of temperatures above
Water for injection is referred to as high temperature point with point, and the water for injection for being used below 70 DEG C is referred to as colod-application point with point.So colod-application
Point just needs cooling system, and the water for injection not less than 70 DEG C is cooled to 70 DEG C hereinafter, to meet colod-application point to water for injection
Temperature requirement.
However, at least there is the pipe network of branch pipe(tube) rear end in the multiple colod-application cooling systems of water for injection in current industry
Stagnant water or discharge and the problem of waste a large amount of injection waters or bye-pass cold water returns to main line and main line temperature is caused to reduce simultaneously
Waste mass energy.
For example, a kind of water for injection cooling system in the prior art as shown in Fig. 1 comprising main pipeline, branch pipe
Road, cooling component and the colod-application point of several groups, branch pipe(tube) are connected to by cooling component with main pipeline, can be to inflow branch pipe
Water for injection in road cools down, and makes the water for injection flowed in branch pipe(tube) lower than 70 DEG C；In addition, increasing on branch pipe(tube) more
The colod-application point of group, consequently facilitating control pipe network crushing, and the cost of construction investment and operation can be reduced；But the system due to
Provided with the colod-application point of multiple groups, and the water for injection in branch pipe(tube) lower than 70 DEG C flows back into main pipeline in order to prevent, therefore works as branch pipe
The colod-application point of road front end can have stagnant water when with water in the pipe network of branch pipe(tube) rear end, can not effective control system microorganism
Load.In addition, if preventing stagnant water by the way of carrying out discharge using branch pipe(tube) end or periodically discharging, it will increase system is tested
The workload and compliance challenge of card.
Summary of the invention
The purpose of the present invention is to provide a kind of water for injection cooling systems based on how colod-application point, to solve above-mentioned background
The problem of being proposed in technology.
To achieve the above object, one embodiment of the present of invention provides the following technical solutions:
A kind of water for injection cooling system based on how colod-application point, the branch pipe including main pipeline and equipped with the colod-application point of several groups
Road, the front end and end of the branch pipe(tube) pass through cooling component respectively and the 4th valve is connected with main pipeline；Wherein, described
Several groups are additionally provided on branch pipe(tube) for preventing the reflux mechanism in branch pipe(tube) there are stagnant water, the reflux mechanism is arranged in phase
Between two groups of adjacent colod-application points；It is additionally provided on the main pipeline for controlling water for injection flow velocity in main pipeline and branch pipe(tube)
Pressure regulator valve.
A kind of preferred embodiment that the present invention uses, the reflux mechanism include the 5th valve and communicating pipe, and described the
Five valves are located on branch pipe(tube), the rear end of the 5th valve are arranged in the communicating pipe, and the communicating pipe is equipped with the 6th
Valve；The both ends of the communicating pipe are communicated with main pipeline and branch pipe(tube) respectively.
A kind of preferred embodiment that the present invention uses, the 5th valve and the 6th valve are diaphragm valve.
Another preferred embodiment that the present invention uses, the main pipeline are equipped with the U-shaped bend pipe of several groups, and described is U-shaped
Bend pipe is communicated by communicating pipe with branch pipe(tube).
Another preferred embodiment that the present invention uses, the cooling component are heat exchanger.
Another preferred embodiment that the present invention uses, the cooling component are double tubesheet tubular heat exchanger.
Another preferred embodiment that the present invention uses, the cooling component respectively with chilled water import and chilled water outlet
It is connected.
Another preferred embodiment that the present invention uses, the pressure regulator valve are diaphragm valve.
The outer wall of another preferred embodiment that the present invention uses, the branch pipe(tube) is equipped with ultrasonic flowmeter.
The above-mentioned technical proposal of the offer of the embodiment of the present invention has following technical effect that compared with the prior art
(1) the water for injection cooling system that the embodiment of the present invention provides is easy to operate, by the way that multiple groups are arranged on branch pipe(tube)
It is colod-application, use of the colod-application point of multiple groups in workshop to 70 DEG C of water for injection is lower than can be met, simultaneously so as to reduce system
Construction and operating cost.
(2) the embodiment of the present invention is between two groups of adjacent colod-application points by being arranged the 5th valve and communicating pipe, and
6th valve is set on communicating pipe, the 5th valve of switch and the 6th valve can be selected wherein one or more groups of colod-application to meet
Point also ensures the presence without stagnant water in branch pipe(tube) to the use lower than 70 DEG C of water for injection, is so as to effectively control
The microbial load of system, to avoid the contaminated risk of water for injection occurs.
(3) embodiment of the invention is also by using being connected with the double tubesheet tubular heat exchanger of chilled water as cooling group
The rate of temperature fall to water for injection can be improved in part, makes so as to meet colod-application point in time to lower than 70 DEG C of waters for injection
Use demand.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the water for injection cooling system comprising how colod-application point in the prior art.
Fig. 2 is a kind of structural schematic diagram for water for injection cooling system based on how colod-application point that embodiment 1 provides.
Fig. 3 is a kind of structural schematic diagram for water for injection cooling system based on how colod-application point that embodiment 2 provides.
In figure: 1- main pipeline, the import of 2- water for injection, the outlet of 3- water for injection, 4- branch pipe(tube), the colod-application point of 5-, 6- cooling
Component, the first valve of 7-, the second valve of 8-, 9- third valve, the 4th valve of 10-, the 5th valve of 11-, 12- communicating pipe, 13-
Six valves, 14-U type bend pipe, 15- chilled water import, 16- chilled water outlet, 17- ultrasonic flowmeter, 18- pressure regulator valve.
Specific embodiment
Following specific embodiment is the tool made in conjunction with the attached drawing provided in this specification to the technical solution of the application
Body, clearly description.Wherein, the attached drawing of specification is intended merely to for the technical solution of the application being presented more clear bright
, the shape or size in actual production or use are not represented, and can not be using the label of attached drawing as related power
The limitation that benefit requires.
In addition, the term used should make the understanding of broad sense, for the technology of this field in the description of the present application
For personnel, the concrete meaning of term can be understood according to actual concrete condition.For example, term employed in the application
" installation " can be defined as that either non-removable fixed installation etc. is removably fixedly mounted；Used term " setting "
" being equipped with " can be defined as contact setting or not in contact with formula setting etc.；Used term " connection " can with " being connected "
To be defined as being fixedly connected or the mechanical connection of movable connection, also may be defined as being electrically connected etc.；Used term "
One ", " second " etc. is used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance or implicitly indicates indicated
Technical characteristic quantity；Used term " front end ", " rear end " and " end ", is on the basis of water (flow) direction；It is used
Noun of locality term be with reference to the accompanying drawings or according to being subject to direction defined in actual conditions and common knowledge.
Embodiment 1
Referring to attached drawing 2, this embodiment offers a kind of water for injection cooling systems based on how colod-application point, including 1 He of main pipeline
Branch pipe(tube) 4, the both ends of the main pipeline 1 are connected with water for injection import 2 and water for injection outlet 3 respectively, the injection
It is connected with the stocking system of water for injection with water inlet 2 and water for injection outlet 3.The front end of the main pipeline 1 is equipped with the
One valve 7, the first valve 7 are manual diaphragm valve.The front end phase that the front end of the branch pipe(tube) 4 passes through cooling component 6 and main pipeline 1
Connection, and it is equipped with the second valve 8, the second valve 8 is also manual diaphragm valve；The end of the branch pipe(tube) 4 and the end of main pipeline 1
It is connected, and is equipped with the 4th valve 10, the 4th valve 10 is pneumatic diaphragm valve.
Further, in order to reduce the construction and operating cost of system, it is colod-application that the branch pipe(tube) 4 is equipped with several groups
5 are put, is equipped with third valve 9 on the colod-application point 5 of the several groups, and wherein the end of branch pipe(tube) 4 is arranged in one group of colod-application point 5
End.It is used to prevent the reflux mechanism in branch pipe(tube) 4 there are stagnant water in addition, being additionally provided with several groups on the branch pipe(tube) 4, it is described
Reflux mechanism is arranged between the colod-application point 5 of adjacent two groups.Specifically, the reflux mechanism include the 5th valve 11 be connected to
Pipe 12, the 5th valve 11 are located on branch pipe(tube) 4, and the rear end of the 5th valve 11, and institute is arranged in the communicating pipe 12
The 6th valve 13 is additionally provided on the communicating pipe 12 stated；The both ends of the communicating pipe 12 are communicated with main pipeline 1 and branch pipe(tube) 4 respectively.
Wherein, the 5th valve 11 is located near the connectivity part of colod-application point 5 and branch pipe(tube) 4, the communicating pipe 12 and branch pipe(tube) 4
Connectivity part be arranged near the 5th valve 11.
Wherein, the third valve 9, the 5th valve 11 and the 6th valve 13 are pneumatic diaphragm valve, the supervisor
Road 1 is equipped with the U-shaped bend pipe 14 of several groups, and the both ends of the U-shaped bend pipe 14 are connected with main pipeline 1, the bottom of the U-shaped bend pipe 14
Portion with branch pipe(tube) 4 by being connected communicating pipe 12.By the 5th valve 11 near the colod-application point 5 of selective switch each group and even
The 6th valve 13 on siphunculus 12, can guarantee the water for injection in each section of branch pipe(tube) 4 can be in the state of flowing, so as to
To avoid generating stagnant water in branch pipe(tube) 4, and can effective control system microbial load.
Further, in order to improve system to the cooling efficiency of water for injection, the cooling component 6 is in the prior art
Double tubesheet tubular heat exchanger is connected with chilled water import 15 and chilled water outlet 16 respectively；The chilled water import 15
It is connected with chilled water stocking system with chilled water outlet 16；By the setting for the component 6 that cools down, main pipeline 1 can be made to flow into
Water for injection fast cooling in branch pipe(tube) 4 higher than 70 DEG C is to the water for injection for being lower than 70 DEG C, so as to meet workshop each group
The use demand of colod-application 5 pairs of water for injection of point.
The embodiment provide water for injection cooling system, when in use, by open the first valve 7, the second valve 8,
5th valve 11 and the 4th valve 10, and third valve 9, closing the 6th valve 13 of each group on the colod-application point 5 of each group are closed, and
It is not passed through chilled water in cooling component 6, can realize the circulation of the water for injection in main pipeline 1 and branch pipe(tube) 4 higher than 70 DEG C.
When wherein one group of colod-application point 5 needs to be used below 70 DEG C of water for injection, first close near the colod-application point 5 of the group
5th valve 11, and the 5th valve 11 near the colod-application 5 all colod-application points 5 in front of point of the group is all opened；Simultaneously toward drop
It is passed through chilled water in warm component 6, and opens the 6th valve 13 near the colod-application point 5 of the group, it can be colod-application by opening the group
Third valve 9 on point 5, carries out the use of the water for injection lower than 70 DEG C, and also ensures depositing without stagnant water in branch pipe(tube) 4
?.
In addition, when one group of colod-application point 5 in 4 least significant end of branch pipe(tube) needs to be used below 70 DEG C of water for injection, first
The 4th valve 10 and the 6th all valves 13 are closed, and opens the 5th all valves 11, and is passed through in cooling component 6
Chilled water can carry out the use of the water for injection lower than 70 DEG C by opening the third valve 9 on the colod-application point 5 of the group.
Similarly, it when wherein the colod-application point 5 of multiple groups needs while being used below 70 DEG C of water for injection, first closes and is wherein in
Compared with the 5th valve 11 near one group of colod-application point 5 of rear end, and will be near the colod-application 5 all colod-application points 5 in front of point of the group
5th valve 11 is all opened；It is passed through chilled water in cooling component 6 simultaneously, and opens the 6th valve near the colod-application point 5 of the group
Door 13 can select to open the third valve 9 on the colod-application point 5 of the group and colod-application point 5 in colod-application 5 front end of point of the group, with
Meet the use for the water for injection that the colod-application point 5 of multiple groups is carried out lower than 70 DEG C simultaneously.
In conclusion the water for injection cooling system that the embodiment provides is easy to operate, by being arranged on branch pipe(tube) 4
The colod-application point 5 of multiple groups can meet 5 pairs of the colod-application point of multiple groups in the workshop uses for being lower than 70 DEG C of water for injection, simultaneously so as to drop
The construction and operating cost of low system.In addition, the embodiment between two groups of adjacent colod-application points 5 by being arranged the 5th valve 11
With communicating pipe 12, and the 6th valve 13 of setting on communicating pipe 12, the 5th valve 11 of switch and the 6th valve 13 can be selected
Wherein it is lower than the use of 70 DEG C of water for injection for one or more groups of 5 pairs of colod-application point to meet, and also ensures in branch pipe(tube) 4 without stagnant water
Presence, so as to the microbial load of effective control system, to avoid the contaminated risk of water for injection occurs.
In addition, the embodiment is used as cooling component 6, Ke Yiti by using the double tubesheet tubular heat exchanger for being connected with chilled water
Height is to the rate of temperature fall of water for injection, so as to meet 5 pairs of the colod-application point use demands for being lower than 70 DEG C of water for injection in time.
Embodiment 2
Referring to attached drawing 3, for the ease of the flow velocity of water for injection in control main pipeline 1 and branch pipe(tube) 4, which is in embodiment
It is improved on the basis of 1, the main pipeline 1 is equipped with pressure regulator valve 18, and pressure regulator valve 18 is adjustable diaphragm valve, setting
Between two groups of U-shaped bend pipes 14 in 1 end of main pipeline.In addition, supersonic flow can be passed through on the outer wall of the branch pipe(tube) 4
Meter 17 can detect the flow velocity of water for injection in main pipeline 1 and branch pipe(tube) 4, under the adjusting of cooperation pressure regulator valve 18 just
The flow velocity of water for injection is not less than 0.9m/s in controllable main pipeline 1 and branch pipe(tube) 4.
Wherein, most of if being not provided with pressure regulator valve 18 since the caliber of main pipeline 1 generally can be bigger than branch pipe(tube) 4
Water for injection will flow into the small main pipeline 1 of the big resistance of caliber, and the water in the big branch pipe(tube) 4 of caliber slight drag will be very
It is small.It, can be by water for injection from supervisor to adjust the flow of water for injection in main pipeline 1 so by the setting of pressure regulator valve 18
Road 1 is diverted in branch pipe(tube) 4.
In conclusion the embodiment can pass through ultrasonic wave by the way that pressure regulator valve 18 is arranged compared with the position of end in main pipeline 1
The cooperation of flowmeter 17 and pressure regulator valve 18 controls the flow velocity of the water for injection in main pipeline 1 and branch pipe(tube) 4, thus will not
Cause the challenge of compliance.
It should be noted that above-described embodiment carries out specifically, clearly just for the technical solution and technical characteristic of the application
The description of Chu.And to those skilled in the art, belong to the scheme or feature of the prior art or common knowledge, above
It is not just described in detail in embodiment.
In addition, the technical solution of the application is not limited solely to the above embodiments, those skilled in the art should will illustrate
As a whole, the technical solutions in the various embodiments may also be suitably combined for book, so as to form those skilled in the art
The other embodiments that member is understood that.
Claims (8)
1. a kind of water for injection cooling system based on how colod-application point, including main pipeline (1) and it is equipped with the colod-application point (5) of several groups
Branch pipe(tube) (4), the front end and end of the branch pipe(tube) (4) pass through respectively cooling component (6) and the 4th valve (10) be responsible for
Road (1) is connected, which is characterized in that it is dead for preventing from existing in branch pipe(tube) (4) that several groups are additionally provided on the branch pipe(tube) (4)
The reflux mechanism of water, the reflux mechanism are arranged between the colod-application point (5) of adjacent two groups；On the main pipeline (1) also
Equipped with the pressure regulator valve (18) for controlling main pipeline (1) and the interior water for injection flow velocity of branch pipe(tube) (4).
2. a kind of water for injection cooling system based on how colod-application point according to claim 1, which is characterized in that described
The mechanism that flows back includes the 5th valve (11) and communicating pipe (12), and the 5th valve (11) is located on branch pipe(tube) (4), described
Communicating pipe (12) setting is in the rear end of the 5th valve (11), and the communicating pipe (12) is equipped with the 6th valve (13)；It is described
The both ends of communicating pipe (12) are communicated with main pipeline (1) and branch pipe(tube) (4) respectively.
3. a kind of water for injection cooling system based on how colod-application point according to claim 1, which is characterized in that described
5th valve (11) and the 6th valve (13) are diaphragm valve.
4. a kind of water for injection cooling system based on how colod-application point according to claim 1, which is characterized in that described
Main pipeline (1) is equipped with the U-shaped bend pipe of several groups (14), and the U-shaped bend pipe (14) passes through communicating pipe (12) and branch pipe(tube) (4) phase
It is logical.
5. a kind of water for injection cooling system based on how colod-application point according to claim 1, which is characterized in that described
Cool down component (6) as heat exchanger.
6. a kind of water for injection cooling system based on how colod-application point according to claim 5, which is characterized in that described
Cool down component (6) as double tubesheet tubular heat exchanger.
7. a kind of water for injection cooling system based on how colod-application point according to claim 6, which is characterized in that described
Cooling component (6) is connected with chilled water import (15) and chilled water outlet (16) respectively.
8. a kind of water for injection cooling system based on how colod-application point according to claim 1, which is characterized in that described
Pressure regulator valve (18) is diaphragm valve.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2019102837085 | 2019-04-10 | ||
| CN201910283708 | 2019-04-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110143632A true CN110143632A (en) | 2019-08-20 |
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ID=67596644
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| Application Number | Title | Priority Date | Filing Date |
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| CN201910552403.XA Pending CN110143632A (en) | 2019-04-10 | 2019-06-25 | A kind of water for injection cooling system based on how colod-application point |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114673935A (en) * | 2022-03-18 | 2022-06-28 | 北京双吉制药有限公司 | Injection water distribution system for drug manufacturing |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103388742A (en) * | 2013-07-22 | 2013-11-13 | 上海创洁科技有限公司 | Ultra-pure medium conveying integrated system |
-
2019
- 2019-06-25 CN CN201910552403.XA patent/CN110143632A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103388742A (en) * | 2013-07-22 | 2013-11-13 | 上海创洁科技有限公司 | Ultra-pure medium conveying integrated system |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114673935A (en) * | 2022-03-18 | 2022-06-28 | 北京双吉制药有限公司 | Injection water distribution system for drug manufacturing |
| CN114673935B (en) * | 2022-03-18 | 2024-01-30 | 北京双吉制药有限公司 | Injection water distribution system for drug production |
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