CN110128882A - Steam sterilizing chemistry instruction ink rich in iron ion and its preparation method and application - Google Patents
Steam sterilizing chemistry instruction ink rich in iron ion and its preparation method and application Download PDFInfo
- Publication number
- CN110128882A CN110128882A CN201910419919.7A CN201910419919A CN110128882A CN 110128882 A CN110128882 A CN 110128882A CN 201910419919 A CN201910419919 A CN 201910419919A CN 110128882 A CN110128882 A CN 110128882A
- Authority
- CN
- China
- Prior art keywords
- ink
- steam sterilizing
- rich
- iron ion
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D11/00—Inks
- C09D11/02—Printing inks
- C09D11/03—Printing inks characterised by features other than the chemical nature of the binder
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D11/00—Inks
- C09D11/50—Sympathetic, colour changing or similar inks
Abstract
The invention belongs to chemical ink fields, and in particular to a kind of steam sterilizing chemistry instruction ink and its preparation method and application rich in iron ion.The ink is made of the raw material of following weight percent: binder 15-30%；Iron containing compounds 20-30%；Sulfur-containing compound 5-10%；Catalyst 1-5%；Solvent 40-50%；Preparation method are as follows: firstly, in a solvent by binder dissolution, then, sequentially adding iron containing compounds, sulfur-containing compound and catalyst stirring, then grind, obtaining product；In application, being used for intaglio plate, silk-screen plate, flexographic plate or offset plate, pressure steam sterilizing chemical monitoring indicant product is made.Monitoring method of the present invention is simple and easy, can modulate random color, visual result, accurate, while chemistry instruction ink fades after can be avoided sterilizing, can be avoided the harm of heavy metal；The preparation method and application, it is simple and easy.
Description
Technical field
The invention belongs to chemical ink fields, and in particular to it is a kind of rich in iron ion steam sterilizing chemistry instruction ink and
Preparation method and application.
Background technique
The most commonly used is pressuresteam sterilizations in medical institutions at different levels at present, and the sterilization method is also the most reliable, use
Most extensively.For pressuresteam sterilization, biological indicator is the goldstandard of sterilizing effect monitoring, but since it is expensive, training
The feeding time is longer, the factors such as variant limit the popularization and application of its large area between different batches.Thus, in view of chemical classes
Sterilizing monitoring indicator is without culture and can identify that chemical indicator color change is excellent come quick interpretation result etc. by naked eyes
Point, chemical indicator are widely used in the packet external monitor of pressuresteam sterilization package, monitoring, B-D test and process challenge in packet
Test.
Aqueous steam is made using bismuth organic compound, carbonate, sulphur source and water etc. in 2014/0370604 A1 of US
Sterilization chemical indicator composition, it is more environmentally friendly compared to solvent type component.So far most of commercially available chemical indicator is using metal
Sulfide chromic component uses metallic compound or metal salt, sulphur powder or organic sulfur as sulphur source, by pressuresteam sterilization
Afterwards, two components issue biochemical reaction in the assistance of other auxiliary agents, generate the deeper metal sulfide of color.But due to such change
Learning indicant can directly contact in use with medical instrument, and the heavy metal component in indicant can be inevitably infected with
To operation patient wound, thus there is using the indicant that the heavy metal is formulated the risk of postoperative foreign body rejection.
Currently, intake is excessive containing heavy metals such as lead ion, manganese ion or copper ions in common chemistry instruction ink
Heavy metal will lead to human body heavy metal poisoning.CN201611181226.1 indicates ink using copper-containing compound preparation chemistry,
The harm of lead is avoided, but copper is heavy metal, still remains harm after directly contacting human body.
Summary of the invention
In view of the deficiencies of the prior art, the steam sterilizing chemistry instruction rich in iron ion that the object of the present invention is to provide a kind of
Ink, monitoring method is simple and easy, can modulate random color, visual result, accurate, while can be avoided chemistry after sterilizing
Instruction ink fades, nontoxic, can be avoided the harm of heavy metal, meets different sterilising temp requirements；The present invention mentions simultaneously
For preparation method and application.
Steam sterilizing chemistry of the present invention rich in iron ion indicates ink, by the raw material system of following weight percent
At:
Wherein:
The binder is polyvinyl resin, Corvic, acrylate, phenolic resin, polyester resin
Or the mixture of one or more of polyamide.
The iron containing compounds are one or more of five water ferric sulfate, ferric nitrate, ferric carbonate or ironic citrate
Mixture.
The sulfur-containing compound is the mixture of one or more of sodium thiosulfate, sublimed sulfur or thiocarbamide.
The catalyst is sodium carbonate, sodium bicarbonate, sodium hydroxide, potassium carbonate, saleratus, potassium hydroxide, oxidation
The mixture of one or more of magnesium, magnesium hydroxide or basic magnesium carbonate.
The solvent is the mixture of one or more of ethyl acetate, cyclohexanone or butyl acetate.
The preparation method of the steam sterilizing chemistry instruction ink rich in iron ion, steps are as follows:
Firstly, in a solvent by binder dissolution, then, sequentially adding iron containing compounds, sulfur-containing compound and catalyst
Stirring, then grind, obtain product.
The mixing time is 0.5-1 hours.
Described is ground to be ground to using three-roll grinder with Hegman grind gage measurement fineness less than 10 microns.
The application of the steam sterilizing chemistry instruction ink rich in iron ion, is adjustable as water-based ink or oiliness oil
Ink can be used for any format such as intaglio plate, silk-screen plate, flexographic plate or offset plate, any form of pressuresteam sterilization can be made
Chemical monitoring indicant product.
Compared with prior art, beneficial effects of the present invention are as follows:
(1) present invention uses iron containing compounds, it is modulated go out random color, can be changed to after steam sterilizing and be with black
Main terminal color, so that instruction result is more intuitive, accurate, and application range is wider.
(2) the steam sterilizing chemistry instruction ink produced by the present invention rich in iron ion is after pressuresteam sterilization changes colour
Chemistry instruction ink be not in situation of fading.
(3) chemistry instruction ink main component of the present invention is iron, and iron is the necessary element of body, can give medical care people
Member provides a kind of heavy metal free environment, and the oxidisability of iron is stronger, can further decrease the risk of postoperative foreign body rejection, safety
Performance is stronger.
(4) the steam sterilizing chemistry instruction ink monitoring method using produced by the present invention rich in iron ion is simple and easy,
Visual result is accurate, at the same avoid sterilizing after chemistry instruction ink fade.
(5) by adjusting the adding proportion of different raw material, the needs of different sterilising temp requirements is can satisfy, doctor is reached
The standard of institute's sterilizing application.
(6) preparation method of the present invention, simple and easy, the application method are simple and easy.
Specific embodiment
Below with reference to embodiment, the present invention will be further described, but does not limit the present invention.
All raw materials used in embodiment are commercially available unless otherwise specified.
Embodiment 1
The steam sterilizing chemistry rich in iron ion indicates ink, is coated with instruction ink using screen printing mode,
For producing label indicant, the ink is made of the raw material of following weight percent:
Preparation method is as follows:
Polyvinyl resin is mixed with ethyl acetate, stirring to polyvinyl resin is dissolved completely in ethyl acetate, is added
Five water ferric sulfate and sodium thiosulfate after adding sodium carbonate stirring 1 hour, then are ground to three-roll grinder and use Hegman fineness grind
Meter measurement fineness is made less than 10 microns.
Embodiment 2
The steam sterilizing chemistry rich in iron ion indicates ink, is coated with instruction ink using intaglio printing mode, uses
In production instruction card indicant, the ink is made of the raw material of following weight percent::
Preparation method is as follows:
Corvic is mixed with cyclohexanone, stirring to Corvic is dissolved completely in cyclohexanone, is added
Tartaric acid iron and thiocarbamide after adding basic magnesium carbonate stirring 0.5 hour, then are ground to three-roll grinder and use Hegman grind gage
It measures fineness and is made less than 10 microns.
Embodiment 3
The steam sterilizing chemistry rich in iron ion indicates ink, is coated with instruction ink using flexographic plate mode of printing,
For producing adhesive tape indicant, the ink is made of the raw material of following weight percent:
Preparation method is as follows:
Phenolic resin and polyester resin are mixed with ethyl acetate, stirring to phenolic resin and polyester resin is dissolved completely in
In ethyl acetate, ironic citrate and sodium thiosulfate is added, adds sodium hydroxide and after potassium carbonate stirs 0.5 hour, then uses
Three-roll grinder, which is ground to, to be made with Hegman grind gage measurement fineness less than 10 microns.
Certainly, above content is only presently preferred embodiments of the present invention, be should not be construed as limiting to implementation of the invention
Example range.The present invention is also not limited to the example above, and those skilled in the art are in essential scope of the invention
Interior made all the changes and improvements etc., should all belong in patent covering scope of the invention.
Claims (10)
1. a kind of steam sterilizing chemistry rich in iron ion indicates ink, it is characterised in that: by the raw material of following weight percent
It is made:
The chemistry instruction ink is water-based ink or oil-based ink.
2. the steam sterilizing chemistry according to claim 1 rich in iron ion indicates ink, it is characterised in that: the company
Splicing is in polyvinyl resin, Corvic, acrylate, phenolic resin, polyester resin or polyamide
One or more of mixtures.
3. the steam sterilizing chemistry according to claim 1 rich in iron ion indicates ink, it is characterised in that: described contains
Iron compound is the mixture of one or more of five water ferric sulfate, ferric nitrate, ferric carbonate, ferrous sulfate or ironic citrate.
4. the steam sterilizing chemistry according to claim 1 rich in iron ion indicates ink, it is characterised in that: described contains
Sulphur compound is the mixture of one or more of sodium thiosulfate, sublimed sulfur or thiocarbamide.
5. the steam sterilizing chemistry according to claim 1 rich in iron ion indicates ink, it is characterised in that: described urges
Agent is sodium carbonate, sodium bicarbonate, sodium hydroxide, potassium carbonate, saleratus, potassium hydroxide, magnesia, magnesium hydroxide or alkali formula
The mixture of one or more of magnesium carbonate.
6. the steam sterilizing chemistry according to claim 1 rich in iron ion indicates ink, it is characterised in that: described is molten
Agent is the mixture of one or more of ethyl acetate, cyclohexanone or butyl acetate.
7. a kind of preparation method of any steam sterilizing chemistry instruction ink rich in iron ion of claim 1-6,
Be characterized in that: steps are as follows:
Firstly, in a solvent by binder dissolution, then, iron containing compounds, sulfur-containing compound and catalyst stirring are sequentially added,
It grinds again, obtains product.
8. the preparation method of the steam sterilizing chemistry instruction ink according to claim 7 rich in iron ion, feature exist
In: the mixing time is 0.5-1 hours.
9. the preparation method of the steam sterilizing chemistry instruction ink according to claim 7 rich in iron ion, feature exist
In: described is ground to be ground to using three-roll grinder with Hegman grind gage measurement fineness less than 10 microns.
10. a kind of application of any steam sterilizing chemistry instruction ink rich in iron ion of claim 1-6, feature
It is: for intaglio plate, silk-screen plate, flexographic plate or offset plate, pressure steam sterilizing chemical monitoring indicant product is made.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910419919.7A CN110128882A (en) | 2019-05-20 | 2019-05-20 | Steam sterilizing chemistry instruction ink rich in iron ion and its preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910419919.7A CN110128882A (en) | 2019-05-20 | 2019-05-20 | Steam sterilizing chemistry instruction ink rich in iron ion and its preparation method and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110128882A true CN110128882A (en) | 2019-08-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910419919.7A Pending CN110128882A (en) | 2019-05-20 | 2019-05-20 | Steam sterilizing chemistry instruction ink rich in iron ion and its preparation method and application |
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| CN (1) | CN110128882A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115093747A (en) * | 2022-07-14 | 2022-09-23 | 山东新华医疗器械股份有限公司 | Chemical indicating ink for pressure steam sterilization and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1396451A (en) * | 2001-12-31 | 2003-02-12 | 阎辉 | Composite chemical indicator for pressure vapour sterilization and its preparing process and application |
| JP2006104346A (en) * | 2004-10-06 | 2006-04-20 | Nichiyu Giken Kogyo Co Ltd | Offset printing ink composition for high pressure steam sterilization indicator |
| CN101481727A (en) * | 2009-01-22 | 2009-07-15 | 江门市新时代外用制剂有限公司 | Pressure steam sterilizing effect indicator and use thereof |
| CN106634173A (en) * | 2016-12-20 | 2017-05-10 | 山东新华医疗器械股份有限公司 | Unfading pressure steam sterilization chemical indicating ink as well as preparation method and application thereof |
-
2019
- 2019-05-20 CN CN201910419919.7A patent/CN110128882A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1396451A (en) * | 2001-12-31 | 2003-02-12 | 阎辉 | Composite chemical indicator for pressure vapour sterilization and its preparing process and application |
| JP2006104346A (en) * | 2004-10-06 | 2006-04-20 | Nichiyu Giken Kogyo Co Ltd | Offset printing ink composition for high pressure steam sterilization indicator |
| CN101481727A (en) * | 2009-01-22 | 2009-07-15 | 江门市新时代外用制剂有限公司 | Pressure steam sterilizing effect indicator and use thereof |
| CN106634173A (en) * | 2016-12-20 | 2017-05-10 | 山东新华医疗器械股份有限公司 | Unfading pressure steam sterilization chemical indicating ink as well as preparation method and application thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115093747A (en) * | 2022-07-14 | 2022-09-23 | 山东新华医疗器械股份有限公司 | Chemical indicating ink for pressure steam sterilization and preparation method thereof |
| CN115093747B (en) * | 2022-07-14 | 2022-11-08 | 山东新华医疗器械股份有限公司 | Chemical indicating ink for pressure steam sterilization and preparation method thereof |
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| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190816 |