CN110128769A - A kind of dual antibacterial film of allicin/chitosan and the preparation method and application thereof - Google Patents
A kind of dual antibacterial film of allicin/chitosan and the preparation method and application thereof Download PDFInfo
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- CN110128769A CN110128769A CN201910258024.XA CN201910258024A CN110128769A CN 110128769 A CN110128769 A CN 110128769A CN 201910258024 A CN201910258024 A CN 201910258024A CN 110128769 A CN110128769 A CN 110128769A
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
- C08J5/18—Manufacture of films or sheets
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2300/00—Characterised by the use of unspecified polymers
- C08J2300/16—Biodegradable polymers
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2329/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal, or ketal radical; Hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Derivatives of such polymer
- C08J2329/02—Homopolymers or copolymers of unsaturated alcohols
- C08J2329/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
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- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2400/00—Characterised by the use of unspecified polymers
- C08J2400/16—Biodegradable polymers
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- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2405/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2401/00 or C08J2403/00
- C08J2405/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/36—Sulfur-, selenium-, or tellurium-containing compounds
- C08K5/41—Compounds containing sulfur bound to oxygen
- C08K5/42—Sulfonic acids; Derivatives thereof
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Abstract
The present invention relates to a kind of dual antibacterial film of allicin/chitosan and the preparation method and application thereof, each component including following weight percentage: 0.2~1.5wt% chitosan, 0.44~0.48wt% acid, 1.9~4.6wt% degradable basis material, 0.19~3.5wt% surfactant, 0.48~3.5wt% allicin and 87.7~95.9wt% deionized water.Film prepared by the present invention has excellent mechanical performance；Allicin, chitosan have good antibacterial effect to staphylococcus aureus, Escherichia coli respectively, and the two synergistic effect enables the shelf life of food substantially to extend.In addition compared with traditional film, film prepared by the present invention is environmentally friendly, has good biological degradability, has broad application prospects in food packaging applications.
Description
Technical field
The present invention relates to a kind of antibacterial films and the preparation method and application thereof, and in particular to a kind of allicin/chitosan is double
Weight antibacterial film and the preparation method and application thereof, belongs to film composite material technical field.
Background technique
Bread is the staff of life, and food and our daily life are closely bound up.But the corruption of food not only gives the body of people
Body health causes great harm, while also resulting in the serious waste of resource.According to statistics, the whole world has number with hundred million tons every year
Food abandoned due to putrid and deteriorated.Cause many because being known as of food apoilage, such as biological factor (microorganism, parasitism
Worm), chemical factor (enzyme in food tissue) and physical factor (illumination, storage temperature, humidity) etc..For most of food
For, the breeding of microorganism is the main inducing of food spoilage.Microorganism is survived in extensively in our ambient enviroment, and food exists
It inevitably will receive the microbial contamination of different type and quantity during processing and storage and transportation, and when ambient environmental conditions are suitable
When suitable, they will mushroom out breeding, cause food it is quick corruption with it is rotten.In order to extend the shelf life of food, mesh
Preceding method common in the market is that the additives of some individual packets is added in food packaging to improve the inside of packing container
Environment, there are also add some antibacterial agents directly in food to achieve the purpose that extend the shelf life.But with people's life water
The big health perception of flat raising, people also gradually increases, and food, which will not only play, can satisfy the basic of daily life demand
Function, while also proposed new challenge to the physical and mental health of people.Traditional food packaging mode safety coefficient is low, function list
One, this demand can not be competent at.Therefore, a kind of thin-film material with excellent anti-bacterium capability is studied, it can be to different type
Bacterium all have extraordinary bacteriostasis, thus play extend food shelf life be highly desirable.
For this purpose, the present invention select it is universally acknowledged it is safe and nontoxic, can natural degradation high molecular material polyvinyl alcohol conduct
The substrate of film prepares one kind using chitosan and two kinds of the allicin natural materials with different anti-microbial properties as anti-biotic material
The dual antibacterial film material of allicin/chitosan.
Summary of the invention
Insufficient to solve the prior art, the present invention provides a kind of dual antibacterial film of allicin/chitosan and its preparations
Method, the present invention provides the antimicrobial packaging films of food fresh keeping degree and shelf life, and the antibacterial effect of the antibacterial film is good,
Excellent antibiotic property is shown to Gram-negative bacteria (Escherichia coli) and gram-positive bacteria (staphylococcus aureus)
Can, and preparation process is simple, and it is easy to use.
The purpose of the present invention is what is be achieved through the following technical solutions:
A kind of dual antibacterial film of allicin/chitosan, each component including following weight percentage: including such as the following group
Point: 0.2~1.5wt% chitosan, 0.44~0.48wt% acid, the degradable basis material of 1.9~4.6wt%, 0.19~
3.5wt% surfactant, 0.48~3.5wt% allicin and 87.7~95.9wt% deionized water.
Based on the above-mentioned technical proposal, allicin and chitosan respectively have staphylococcus aureus, Escherichia coli fine
Antibacterial effect, the two synergistic effect, so that the shelf life of food is substantially extended, matrix material of the polyvinyl alcohol as film
Material, the component raw materials such as degradable basis material, chitosan, allicin are safe and harmless, can natural degradation, the preparation method of film
Simply, practical, chitosan also has good filming performance, and the film strength of preparation is high, but matter is crisp, shows as crisp
Property fracture, chitosan and basis material are mixed film forming by us, and what is obtained takes into account its elongation and tensile strength.
Further, the surfactant is selected from one of Tween 80, polysorbas20, polysorbate40 or polysorbate60 or more
The mixing of kind.
Further, the acid is selected from one of acetic acid, hydrochloric acid or sulfuric acid.
Further, the degradable basis material is selected from one of PVA220, PVA117, PVA217 or PVA420.
Based on the above-mentioned technical proposal, the degradable PVA of the polyvinyl alcohol has good filming performance, the film of preparation
Good toughness, elongation at break is high, but tensile strength is low, we form a film chitosan and polyvinyl alcohol, and what is obtained takes into account
Its elongation and tensile strength.
The present invention also provides a kind of preparation methods of dual antibacterial film of allicin/chitosan, which is characterized in that including
Following steps:
S1, stirring and dissolving in acid solution is added in chitosan, obtains chitosan solution；
S2, it will be swollen in degradable basis material addition deionized water, then dissolve by heating, and be centrifuged removal impurity, obtain
Basis material solution；
S3, it the obtained solution of step S1 and step S2 is uniformly mixed and surfactant is added stirs evenly, must mix
Solution；
S4, the mixed solution and dripping allicin obtained to step S3, with high-shearing dispersion emulsifying machine dispersion mixing solution,
Then will mixed solution be added centrifuge in carry out evacuation and centrifugal degassing, obtain the dual antibacterial film of allicin/chitosan at film liquid；
S5, the dual antibacterial film of allicin/chitosan that step S4 is obtained is paved with mold table with the tape casting at film liquid
Face, and mold is placed in drying in drying box, film is taken off after taking-up obtains the dual antibacterial film of allicin/chitosan.
Based on the above-mentioned technical proposal, environment will not be polluted by molding being dried with drying box, prepared by this method
Dual antibacterial film can be with natural degradation.
Further, in step S1, the concentration of the chitosan solution is 5g/L~32g/L.
Further, in step S2, described matrix material solution concentration is 40g/L~100g/L.
Further, the mass fraction of the surfactant in the mixed solution in step S3 is 0.19%~3.5%.Step
It stirs and can be stirred on the magnetic stirring apparatus of constant temperature in rapid S3.
Further, the mass fraction of the allicin in the mixed solution in step S4 is 0.48%~3.5%.
The present invention also provides a kind of purposes of dual film, are used as antibacterial film and pack.
The beneficial effects of the present invention are:
It, can be simultaneously to different type 1. the dual antibacterial film antibacterial effect of allicin/chitosan provided by the invention is excellent
Bacterium (Gram-negative bacteria and gram-positive bacteria) generate strong inhibiting effect, can have during the storage of food
Effect extends the freshness of food and the shelf life of food.
2. the component raw materials such as polyvinyl alcohol selected by the present invention, chitosan, allicin, safe and harmless, can natural degradation,
The preparation method of film is simple, practical.
3. the present invention has good elongation and tensile strength.
Detailed description of the invention
In conjunction with the following drawings, it is specifically described the embodiment of the present invention or technical solution in the prior art, but is described below
In attached drawing for the present invention be only some embodiments of the present invention, rather than limit the scope of the invention.
Fig. 1 is film prepared in embodiment 4 and 5 respectively to the antibacterial effect of staphylococcus aureus and Escherichia coli
Fruit.
Specific embodiment
The principle and features of the present invention will be described below with reference to the accompanying drawings, and illustrated embodiment is served only for explaining the present invention,
It is not intended to limit the scope of the present invention.
Embodiment 1
0.5g chitosan is added to the aqueous acetic acid of 100mL1% (V/V), stirring and dissolving is stood for 24 hours in 4 DEG C of refrigerators；
By 10g polyvinyl alcohol 220 be added 100mL deionized water in, stirring swelling, be heated to 45 DEG C until polyvinyl alcohol be completely dissolved,
10min is centrifuged with the filtering of 100 mesh gauzes or revolving speed 4000rpm；The solution of above-mentioned configuration is mixed, stirring keeps its dispersion equal
It is even, matrix is obtained into film liquid.Then by matrix at the tween80 surfactant that 4g is added in film liquid, stirring becomes equal to solution
One, 4g allicin is added, shearing dispersion 1min, obtains white emulsion under the revolving speed of 10000rpm.The white cream that will be obtained
Liquid is centrifuged 10min under 5000rpm speed conditions, carries out evacuation and centrifugal degassing, obtains into film liquid.It will be poured on mirror steel plate at film liquid
Casting film-forming, 35 DEG C of oven drying 10h obtain the dual antibacterial film of allicin/chitosan.
Prepared film tensile strength is 40.92MPa, elongation at break 77.5%；With staphylococcus aureus and
Escherichia coli are research object, are compareed with blank group, and two distinct types of total plate count significantly reduces.
Embodiment 2
3.2g chitosan is added to the aqueous acetic acid of 100mL1% (V/V), stirring and dissolving is stood for 24 hours in 4 DEG C of refrigerators；
By 4g polyvinyl alcohol 420 be added 100mL deionized water in, stirring swelling, be heated to 45 DEG C until polyvinyl alcohol be completely dissolved, use
The filtering of 100 mesh gauzes or revolving speed 4000rpm are centrifuged 10min；The solution of above-mentioned configuration is mixed, stirring keeps its dispersion equal
It is even, matrix is obtained into film liquid.Then by matrix at the tween20 surfactant that 0.4g is added in film liquid, stirring to solution becomes
It is uniform, 1g allicin is added, shearing dispersion 1min, obtains white emulsion under the revolving speed of 10000rpm.The white that will be obtained
Lotion is centrifuged 10min under 5000rpm speed conditions, carries out evacuation and centrifugal degassing, obtains into film liquid.Mirror steel plate will be poured at film liquid
Upper casting film-forming, drying at room temperature 72h obtain the dual antibacterial film of allicin/chitosan.
Prepared film tensile strength is 60.92MPa, elongation at break 80.91%；With staphylococcus aureus and
Escherichia coli are research object, are compareed with blank group, and two distinct types of total plate count significantly reduces.
Embodiment 3
2.4g chitosan is added to the aqueous acetic acid of 100mL1% (V/V), stirring and dissolving is stood for 24 hours in 4 DEG C of refrigerators；
By 6g polyvinyl alcohol 117 be added 100mL deionized water in, stirring swelling, be heated to 45 DEG C until polyvinyl alcohol be completely dissolved, use
The filtering of 100 mesh gauzes or revolving speed 4000rpm are centrifuged 10min；The solution of above-mentioned configuration is mixed, stirring keeps its dispersion equal
It is even, matrix is obtained into film liquid.Then by matrix at the tween60 surfactant that 2g is added in film liquid, stirring becomes equal to solution
One, 2g allicin is added, shearing dispersion 1min, obtains white emulsion under the revolving speed of 10000rpm.The white cream that will be obtained
Liquid is centrifuged 10min under 5000rpm speed conditions, carries out evacuation and centrifugal degassing, obtains into film liquid.It will be poured on mirror steel plate at film liquid
Casting film-forming, drying at room temperature 48h obtain the dual antibacterial film of allicin/chitosan.
Prepared film tensile strength is 46.92MPa, elongation at break 81.67%；With staphylococcus aureus and
Escherichia coli are research object, are compareed with blank group, and two distinct types of total plate count significantly reduces.
Embodiment 4
2g chitosan is added to the aqueous acetic acid of 100mL1% (V/V), stirring and dissolving is stood for 24 hours in 4 DEG C of refrigerators；It will
10g polyvinyl alcohol 217 be added 100mL deionized water in, stirring swelling, be heated to 45 DEG C until polyvinyl alcohol be completely dissolved, use
The filtering of 100 mesh gauzes or revolving speed 4000rpm are centrifuged 10min；The solution of above-mentioned configuration is mixed, stirring keeps its dispersion equal
It is even, matrix is obtained into film liquid.Then by matrix at the tween80 surfactant that 8g is added in film liquid, stirring becomes equal to solution
One, 8g allicin is added, shearing dispersion 1min, obtains white emulsion under the revolving speed of 10000rpm.The white cream that will be obtained
Liquid is centrifuged 10min under 5000rpm speed conditions, carries out evacuation and centrifugal degassing, obtains into film liquid.It will be poured on mirror steel plate at film liquid
Casting film-forming, 35 DEG C of oven drying 16h obtain the dual antibacterial film of allicin/chitosan.
Prepared film tensile strength is 24.05MPa, elongation at break 52.5%；With staphylococcus aureus and
Escherichia coli are research object, are compareed with blank group, and two distinct types of total plate count significantly reduces.
Embodiment 5
2g chitosan is added to the aqueous acetic acid of 100mL1% (V/V), stirring and dissolving is stood for 24 hours in 4 DEG C of refrigerators；It will
10g polyvinyl alcohol 220 be added 100mL deionized water in, stirring swelling, be heated to 45 DEG C until polyvinyl alcohol be completely dissolved, use
The filtering of 100 mesh gauzes or revolving speed 4000rpm are centrifuged 10min；The solution of above-mentioned configuration is mixed, stirring keeps its dispersion equal
It is even, matrix is obtained into film liquid.Then by matrix at the tween80 surfactant that 8g is added in film liquid, stirring becomes equal to solution
One, 6g allicin is added, shearing dispersion 1min, obtains white emulsion under the revolving speed of 10000rpm.The white cream that will be obtained
Liquid is centrifuged 10min under 8000rpm speed conditions, carries out evacuation and centrifugal degassing, obtains into film liquid.It will be poured on mirror steel plate at film liquid
Casting film-forming, 35 DEG C of oven drying 20h obtain the dual antibacterial film of allicin/chitosan.
Prepared film tensile strength is 35.27MPa, elongation at break 62.92%；With staphylococcus aureus and
Escherichia coli are research object, are compareed with blank group, and two distinct types of total plate count significantly reduces.
Embodiment 6
2g chitosan is added to the aqueous acetic acid of 100mL1% (V/V), stirring and dissolving is stood for 24 hours in 4 DEG C of refrigerators；It will
10g polyvinyl alcohol 220 be added 100mL deionized water in, stirring swelling, be heated to 45 DEG C until polyvinyl alcohol be completely dissolved, use
The filtering of 100 mesh gauzes or revolving speed 4000rpm are centrifuged 10min；The solution of above-mentioned configuration is mixed, stirring keeps its dispersion equal
It is even, matrix is obtained into film liquid.Then by matrix at the surface tween60 for the tween80 surfactant and 4g that 4g is added in film liquid
Activating agent, stirring become uniform to solution, add 8g allicin, and shearing dispersion 1min, obtains under the revolving speed of 10000rpm
White emulsion.Obtained white emulsion is centrifuged 10min under 5000rpm speed conditions, evacuation and centrifugal degassing is carried out, is formed a film
Liquid.Casting film-forming on mirror steel plate will be poured at film liquid, it is thin to obtain the dual antibacterial of allicin/chitosan by 35 DEG C of oven drying 16h
Film.
Prepared film tensile strength is 21.97MPa, elongation at break 50.23%；With staphylococcus aureus and
Escherichia coli are research object, are compareed with blank group, and two distinct types of total plate count significantly reduces.
Embodiment 7
2.4g chitosan is added to the aqueous acetic acid of 100mL1% (V/V), stirring and dissolving is stood for 24 hours in 4 DEG C of refrigerators；
By 6g polyvinyl alcohol 220 be added 100mL deionized water in, stirring swelling, be heated to 45 DEG C until polyvinyl alcohol be completely dissolved, use
The filtering of 100 mesh gauzes or revolving speed 4000rpm are centrifuged 10min；The solution of above-mentioned configuration is mixed, stirring keeps its dispersion equal
It is even, matrix is obtained into film liquid.Then by matrix at the surface tween40 for the tween60 surfactant and 1g that 1g is added in film liquid
Activating agent, stirring become uniform to solution, add 2g allicin, and shearing dispersion 1min, obtains under the revolving speed of 10000rpm
White emulsion.Obtained white emulsion is centrifuged 10min under 5000rpm speed conditions, evacuation and centrifugal degassing is carried out, is formed a film
Liquid.Casting film-forming on mirror steel plate will be poured at film liquid, drying at room temperature 48h obtains the dual antibacterial film of allicin/chitosan.
Prepared film tensile strength is 51.84MPa, elongation at break 83.72%；With staphylococcus aureus and
Escherichia coli are research object, are compareed with blank group, and two distinct types of total plate count significantly reduces.
Comparative example 1
2g chitosan is added to the aqueous acetic acid of 100mL1% (V/V), stirring and dissolving is stood for 24 hours in 4 DEG C of refrigerators；It will
10g polyvinyl alcohol 220 be added 100mL deionized water in, stirring swelling, be heated to 45 DEG C until polyvinyl alcohol be completely dissolved, use
The filtering of 100 mesh gauzes or revolving speed 4000rpm are centrifuged 10min；The solution of above-mentioned configuration is mixed, stirring keeps its dispersion equal
It is even, it is then centrifuged 10min under 5000rpm speed conditions, carries out evacuation and centrifugal degassing, obtains into film liquid.Mirror surface will be poured at film liquid
Casting film-forming on steel plate, 35 DEG C of oven drying 16h, obtains chitosan anti-bacteria film.
Comparative example 2
10g polyvinyl alcohol 220 is added in 100mL deionized water, stirring swelling, is heated to 45 DEG C until polyvinyl alcohol is complete
Fully dissolved is centrifuged 10min with the filtering of 100 mesh gauzes or revolving speed 4000rpm；The solution of above-mentioned configuration is mixed, stirring makes
It is uniformly dispersed, and obtains matrix into film liquid.Then matrix is added into 2g at the tween80 surfactant that 2g is added in film liquid
Allicin, stirring become uniform to solution, and shearing dispersion 1min, obtains white emulsion under the revolving speed of 10000rpm.It will obtain
White emulsion be centrifuged 10min under 5000rpm speed conditions, carry out evacuation and centrifugal degassing, obtain into film liquid.Mirror will be poured at film liquid
Casting film-forming on the steel plate of face, 35 DEG C of oven drying 16h, obtains allicin antibacterial film.
Application Example
The antibacterial film prepared respectively with the dual antibacterial film and comparative example 1 and 2 of embodiment 1-7 preparation is to golden yellow Portugal
Grape coccus and Escherichia coli do bacteriostatic test, from experimental result as can be seen that in identical dosage and same time, comparative example 1
To staphylococcus aureus substantially without inhibiting effect, comparative example 2 is to Escherichia coli substantially without inhibiting effect, embodiment 1-7
It is fine to the inhibitory effect of two distinct types of strain simultaneously.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all in spirit of the invention and
Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of dual antibacterial film of allicin/chitosan, which is characterized in that each component including following weight percentage:
0.2~1.5wt% chitosan, 0.44~0.48wt% acid, the degradable basis material of 1.9~4.6wt%, 0.19~
3.5wt% surfactant, 0.48~3.5wt% allicin and 87.7~95.9wt% deionized water.
2. the dual antibacterial film of allicin/chitosan according to claim 1, which is characterized in that the surfactant choosing
From the mixing of one or more of Tween 80, polysorbas20, polysorbate40, polysorbate60 or castor oil polyoxyethylene ether.
3. the dual antibacterial film of allicin/chitosan according to claim 1, which is characterized in that it is described acid selected from glacial acetic acid,
One of hydrochloric acid, sulfuric acid.
4. the dual antibacterial film of allicin/chitosan according to claim 1, which is characterized in that the degradable matrix material
Material is selected from one of PVA220, PVA117, PVA217 or PVA420.
5. a kind of preparation method of -4 any dual antibacterial films of allicin/chitosan according to claim 1, feature exist
In including the following steps:
S1, stirring and dissolving in acid solution is added in chitosan, obtains chitosan solution；
S2, it will be swollen in degradable basis material addition deionized water, then dissolve by heating, and be centrifuged removal impurity, obtain base
Body material solution；
S3, it the obtained solution of step S1 and step S2 is uniformly mixed and surfactant is added stirs evenly, obtain mixed solution；
S4, the mixed solution and dripping allicin obtained to step S3, with high-shearing dispersion emulsifying machine dispersion mixing solution, then
Will mixed solution be added centrifuge in carry out evacuation and centrifugal degassing, obtain the dual antibacterial film of allicin/chitosan at film liquid；
S5, the dual antibacterial film of allicin/chitosan that step S4 is obtained is poured into casting film-forming in mold at film liquid, and will
Mold is placed in drying in drying box, obtains the dual antibacterial film of allicin/chitosan.
6. the preparation method of the dual antibacterial film of allicin/chitosan according to claim 5, which is characterized in that step S1
In, the concentration of the chitosan solution is 5g/L~32g/L.
7. the preparation method of the dual antibacterial film of allicin/chitosan according to claim 5, which is characterized in that step S2
In, described matrix material solution concentration is 4g/L~100g/L.
8. the preparation method of the dual antibacterial film of allicin/chitosan according to claim 5, which is characterized in that step S3
In mixed solution in surfactant mass fraction be 0.19%~3.5%, stirring can be in the magnetic stirring apparatus of constant temperature
On be stirred.
9. the preparation method of the dual antibacterial film of allicin/chitosan according to claim 5, which is characterized in that step S4
In mixed solution in allicin mass fraction be 0.48%~3.5%.
10. a kind of be used as antimicrobial packaging film to 4 any dual antibacterial films of allicin/chitosan according to claim 1.
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| CN113527827A (en) * | 2020-04-15 | 2021-10-22 | 北京农学院 | Degradable active film with photosensitive bacteriostatic function and preparation method and application thereof |
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| 王永午: "《现代儿科药物治疗学》", 30 September 1998, 人民军医出版社 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113527827A (en) * | 2020-04-15 | 2021-10-22 | 北京农学院 | Degradable active film with photosensitive bacteriostatic function and preparation method and application thereof |
| CN112760824A (en) * | 2020-12-30 | 2021-05-07 | 淄博华士元环保科技有限公司 | Preparation method of full-biodegradable antibacterial dressing |
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