CN110124090B

CN110124090B - Preparation method of wearable sports bandage for removing bromhidrosis

Info

Publication number: CN110124090B
Application number: CN201910400907.XA
Authority: CN
Inventors: 张一敏; 周伟涛; 何建新; 崔世忠; 李克兢; 欧康康; 杨士贤; 于哲璎; 张方; 李勇
Original assignee: Zhongyuan University of Technology
Current assignee: Zhongyuan University of Technology
Priority date: 2019-05-15
Filing date: 2019-05-15
Publication date: 2021-10-26
Anticipated expiration: 2039-05-15
Also published as: CN110124090A

Abstract

The invention discloses a preparation method of a wearable sports bandage for removing bromhidrosis, which comprises the steps of dissolving polyurethane in a tetrahydrofuran and N, N-dimethylformamide blending solvent, magnetically stirring at 40-50 ℃ until the solution is uniform and stable, and preparing a bandage substrate from a spinning solution in an electrostatic spinning mode at 30-40 ℃ and 35-45% of humidity; dissolving beta-cyclodextrin and silicon dioxide in an N, N-dimethylformamide solvent, performing ultrasonic dispersion for 1-2 h, performing magnetic stirring until the solution is uniform and stable, and preparing a microsphere layer from the spinning solution on the basis of a polyurethane substrate in an electrostatic spraying manner to form a composite film; the composite membrane has the hydrophilic and oleophobic functions and can isolate short-chain fatty acid from bacteria; the membrane is soaked into a solution containing nano silver particles to load the nano silver particles, so that the bromhidrosis caused by the reaction of bacteria and oil substances is further reduced. The method has the advantages of simple process, good operability and good application prospect.

Description

Preparation method of wearable sports bandage for removing bromhidrosis

Technical Field

The invention belongs to the field of sports protective textiles, and particularly relates to a preparation method of a wearable sports bandage capable of removing body odor.

Background

Bromhidrosis, which is a pungent smell dissipated by the action of bacteria and short-chain fatty acid substances formed by mixing human sweat gland secretions with proteins and fats generated in the metabolism process of skin. People suffering from bromhidrosis in China are mainly distributed in southern and inner Mongolia and Xinjiang. The disease does not affect the life of the patient, but can cause rejection of people around the patient and self-depreciation of the patient in the heart when the patient is serious. Bromhidrosis is usually masked by deodorization powder or spraying, but the method is inefficient and does not remove the bromhidrosis from the root, and the method of sealing sweat glands by gluing is also available, but may cause discomfort to human bodies, and the method of removing the sweat glands by surgical operation is used for removing the bromhidrosis, but the risk of the operation and the problems caused by postoperative infection are very serious. Therefore, the idea of the invention is developed and designed to remove body odor wearable bandage from the two aspects of the source of bromhidrosis generation, namely the action of short-chain fatty acid substances in excrement and bacteria.

Therefore, in order to eliminate the bromhidrosis of bromhidrosis people, the design and manufacture of a bromhidrosis prevention bandage product which is low in cost, strong in practicability, low in risk, free of toxic and side effects and comfortable is urgent.

Disclosure of Invention

The invention aims to solve the technical problem of providing a preparation method of a wearable sports bandage for removing bromhidrosis, which can effectively remove the bromhidrosis, stop sweating and remove the bromhidrosis and has low cost.

In order to solve the technical problems, the invention adopts the following technical scheme:

a preparation method of a wearable sports bandage for removing bromhidrosis comprises the following steps:

(1) dissolving polyurethane in a tetrahydrofuran and N, N-dimethylformamide blending solvent, magnetically stirring at 40-50 ℃ until a uniform and stable polyurethane solution is obtained, and then preparing a polyurethane nanofiber membrane with the thickness of 20-100 microns, namely a bandage substrate, by an electrostatic spinning method; the shape of the nanofiber membrane is controlled, and the bandage is endowed with good elasticity and wearability; the shape of the bandage substrate is Y, T and U, and the local shape and the elasticity are adjustable;

(2) dissolving beta-cyclodextrin and silicon dioxide in an N, N-dimethylformamide solvent, performing ultrasonic stirring for 1-2 hours and magnetic stirring until the solution is uniform and stable, and then performing electrostatic spraying on the polyurethane nanofiber membrane prepared in the step (1) to form a microsphere layer to obtain a composite membrane; the spinning solution forms a microsphere layer on the polyurethane matrix in an electrostatic spraying mode, and the composite membrane has special surface interface properties due to the micro-nano structure, so that the composite membrane can be used for preventing bromhidrosis of special people. The bandage can be worn on body to absorb oil components in sweat and isolate bacteria from contact with the oil components. The micro-nano structure endows the composite membrane with special surface interface properties, and can be used for preventing bromhidrosis of special people. In the bandage micro-nano structure, the bell-shaped beta-cyclodextrin has a unique hydrophobic cavity structure, can absorb and include oil components which generate pungent odor in discharge of sweat glands of bromhidrosis people, and prevents odor from leaking;

(3) adding silver nitrate into ammonia water, uniformly mixing, putting into a microwave reactor for reduction reaction to generate nano silver particle solution with an antibacterial effect, immediately cooling to room temperature after complete reaction, soaking the composite membrane prepared in the step (2) into the nano silver particle solution for 2 hours, taking out from the solution, putting into an oven at 80 ℃ for baking for 24 hours to obtain the wearable sports bandage for removing the bromhidrosis, and loading the nano silver particles on the surface of the composite membrane after drying to enable the membrane to have the antibacterial property, so that excrement in sweat is prevented from being digested and decomposed by bacteria to generate irritant gas, and the effect of eliminating the bromhidrosis is achieved.

The molecular weight of the polyurethane in the step (1) is 33600, and the concentration of the polyurethane solution is 8-20 wt%; the mass ratio of tetrahydrofuran to N, N-dimethylformamide in the blending solvent is 1: 1-1: 8, and preferably 1: 1.

In the step (1), the spinning temperature is 30-40 ℃, and the spinning humidity is 35-45%.

In the step (1), the electrostatic spinning loading voltage is 16-26 kv, the collection distance is 15-22 cm, and the jet velocity is 0.08-0.3 ml/h.

In the step (2), the mass ratio of the beta-cyclodextrin to the N, N-dimethylformamide is 1 (4-5).

In the step (2), the addition amount of the silicon dioxide is 2wt% and the diameter of the silicon dioxide is 20nm based on the mass of the beta-cyclodextrin.

In the step (2), the electrostatic spraying parameters are that the loading voltage is 20-26 kv, the collection distance is 16-24 cm, and the jet velocity is 0.02-0.08 ml/h.

The concentration of the silver nitrate in the step (3) is 0.5-1 wt%.

And (4) in the step (3), the power of the microwave reactor is 300-600W.

The invention has the beneficial effects that: the invention utilizes electrostatic spinning and electrostatic spraying to prepare a hydrophilic oleophobic nanofiber composite membrane, polyurethane electrostatic spinning is used as a bandage substrate, beta-cyclodextrin and silicon dioxide are subjected to liquid preparation, ultrasonic treatment, stirring, electrostatic spraying and drying to form a microsphere layer on the surface of the substrate, the micron beta-cyclodextrin and the nano-scale silicon dioxide enable the surface of the composite membrane to have micro/nano roughness and higher porosity, and bell-shaped beta-cyclodextrin has the functions of oil absorption and sealing, can absorb short-chain fatty acid substances discharged by sweat glands of a human body, and can prevent the short-chain fatty acid substances from generating irritant odor under the action of bacteria. Further, the nano silver particles are loaded on the bandage to play a role in sterilization, and the bromhidrosis is radically removed. The method has the advantages of simple process, good operability and good application prospect.

Detailed Description

The invention will be further illustrated with reference to the following specific examples. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Further, it should be understood that various changes or modifications of the present invention may be made by those skilled in the art after reading the teaching of the present invention, and such equivalents may fall within the scope of the present invention as defined in the appended claims.

Example 1

The preparation method of the wearable sports bandage for removing the body odor comprises the following steps:

(1) mixing 0.8g of polyurethane, 4.6g of tetrahydrofuran and 4.6g of N, N-dimethylformamide, magnetically stirring at 40 ℃ and 400rpm until the solution is uniform and stable, carrying out electrostatic spinning on the spinning solution at a loading voltage of 16kv and a collection distance of 15cm and a jet velocity of 0.08ml/h at a temperature of 30 ℃ and a humidity of 40% to prepare a T-shaped bandage substrate with a thickness of 20 mu m;

(2) dissolving 1g of beta-cyclodextrin and 0.1g of silicon dioxide in 4g of N, N-dimethylformamide solvent, performing ultrasonic dispersion for 1h, performing magnetic stirring for 2h at room temperature under the condition of 200rpm until the solution is uniform and stable, and preparing a microsphere layer composite membrane on the basis of a polyurethane substrate layer at 30 ℃ and 35% of humidity in an electrostatic spraying manner with a loading voltage of 20kv, a collection distance of 16cm and a jet speed of 0.02 ml/h; the composite membrane has hydrophilic and oleophobic functions;

(3) adding 0.5wt% of silver nitrate into ammonia water, uniformly mixing, putting into a microwave reactor with the power of 300W for reduction reaction to generate nano silver particles with an antibacterial effect, cooling to room temperature after complete reaction, soaking the prepared composite film into a nano silver particle solution for 2 hours, taking out from the solution, drying in an oven with the temperature of 80 ℃ for 24 hours, and loading the nano silver particles on the surface of the composite film to enable the film to have the antibacterial property, thereby achieving the effect of eliminating bromhidrosis.

The bromhidrosis-removing bandage is used for testing contact angle, elastic stretching force, bactericidal effect and bromhidrosis-removing degree

Example 2

(1) adding polyurethane into a solvent prepared by tetrahydrofuran and N, N-dimethylformamide according to the proportion of 1:1, wherein the concentration of the polyurethane is 10wt%, magnetically stirring the mixture at 40 ℃ and 500rpm until the solution is uniform and stable, preparing a Y-shaped bandage substrate with the thickness of 50 mu m by electrostatic spinning at the jet speed of 0.1ml/h and the temperature of 30 ℃ under the conditions of the loading voltage of 20kv, the collection distance of 17cm and the jet speed of 0.1 ml/h;

(2) mixing beta-cyclodextrin and N, N-dimethylformamide according to a ratio of 1:4, adding 2wt% of silicon dioxide to prepare a spinning solution, ultrasonically dispersing the mixture for 2 hours, magnetically stirring the mixture until the solution is uniform and stable, and preparing the composite membrane by using the spinning solution in an electrostatic spraying mode with a loading voltage of 22kv, a collection distance of 18cm and a jet speed of 0.04ml/h on the basis of a polyurethane substrate layer under the conditions of 30 ℃ and 35% humidity; the composite membrane has hydrophilic and oleophobic functions;

(3) adding 0.8wt% of silver nitrate into ammonia water, uniformly mixing, putting into a microwave reactor with the power of 400W for reduction reaction to generate nano silver particles with an antibacterial effect, cooling to room temperature after complete reaction, soaking the prepared composite film into a nano silver particle solution for 2 hours, taking out from the solution, drying in an oven with the temperature of 80 ℃ for 24 hours, and loading the nano silver particles on the surface of the composite film to enable the film to have the antibacterial property, thereby achieving the effect of eliminating bromhidrosis.

Example 3

(1) 1.4g of polyurethane, 4.3g of tetrahydrofuran and 4.3g of N, N-dimethylformamide are mixed, magnetically stirred at 40 ℃ and 500rpm until the solution is uniform and stable, the spinning solution is subjected to electrostatic spinning at a loading voltage of 22kv, a collection distance of 20cm and a jet velocity of 0.2ml/h at a temperature of 30 ℃ and a humidity of 40% to prepare a U-shaped bandage substrate with a thickness of 80 mu m;

(2) mixing beta-cyclodextrin and N, N-dimethylformamide according to a ratio of 1:5, adding 1wt% of silicon dioxide to prepare a spinning solution, ultrasonically dispersing the mixture for 2 hours, magnetically stirring the mixture until the solution is uniform and stable, and preparing the composite membrane by using the spinning solution in an electrostatic spraying mode with a loading voltage of 24kv, a collection distance of 22cm and a jet speed of 0.06ml/h on the basis of a polyurethane substrate layer under the conditions of 30 ℃ and 35% humidity; the composite membrane has hydrophilic and oleophobic functions;

(3) adding 1.0wt% of silver nitrate into ammonia water, uniformly mixing, putting into a microwave reactor with the power of 500W for reduction reaction to generate nano silver particles with an antibacterial effect, cooling to room temperature after complete reaction, soaking the prepared composite film into a nano silver particle solution for 2 hours, taking out from the solution, drying in an oven with the temperature of 80 ℃ for 24 hours, and loading the nano silver particles on the surface of the composite film to enable the film to have the antibacterial property, thereby achieving the effect of eliminating bromhidrosis.

Example 4

(1) 1.6g of polyurethane, 4.2g of tetrahydrofuran and 4.2g of N, N-dimethylformamide are mixed, magnetically stirred at 40 ℃ and 600rpm until the solution is uniform and stable, the spinning solution is subjected to electrostatic spinning at a loading voltage of 26kv, a collection distance of 22cm and a jet velocity of 0.3ml/h at a temperature of 30 ℃ and a humidity of 40% to prepare a T-shaped nanofiber membrane with a thickness of 100 mu m;

(2) dissolving 1g of beta-cyclodextrin and 0.1g of silicon dioxide in 5g of N, N-dimethylformamide solvent, performing ultrasonic dispersion for 1h, performing magnetic stirring for 2h at room temperature under the condition of 200rpm until the solution is uniform and stable, and preparing a microsphere layer composite membrane on the basis of a polyurethane substrate layer at 35 ℃ and 45% of humidity in an electrostatic spraying manner by loading a spinning solution at a loading voltage of 26kv, a collection distance of 24cm and a jet velocity of 0.08 ml/h; the composite membrane has hydrophilic and oleophobic functions;

(3) adding 1.0wt% of silver nitrate into ammonia water, uniformly mixing, putting into a microwave reactor with the power of 600W for reduction reaction to generate nano silver particles with an antibacterial effect, cooling to room temperature after complete reaction, soaking the prepared composite film into a nano silver particle solution for 2 hours, taking out from the solution, drying in an oven with the temperature of 80 ℃ for 24 hours, and loading the nano silver particles on the surface of the composite film to enable the film to have the antibacterial property, thereby achieving the effect of eliminating bromhidrosis.

The bromhidrosis-removing bandage is used for testing contact angle, elastic stretching force, sterilization effect and bromhidrosis-removing degree. The contact angle and tensile properties of the bromhidrosis-removing bandages prepared in examples 1 to 4 are shown in table 1.

TABLE 1 contact angle and tensile Properties of bromhidrosis-removing bandages prepared in examples 1 to 4

As can be seen from the above table, the bandage prepared by the method has good and stable hydrophilic effect due to the hydrophilic microsphere layer, and has good oleophobic property under water, which indicates that sweat discharged from a human body can effectively absorb water and permeate the bandage, and the bandage can absorb grease to isolate the bandage from bacteria, and tests show that the hydrophilic and underwater oleophobic ability of the microsphere layer spun when beta-cyclodextrin and N, N-dimethylformamide are in a ratio of 1:5, the electrostatic spraying loading voltage is 24kv, the collection distance is 22cm, and the jet speed is 0.06mL/h is the best. The polyurethane is used as the substrate of the composite film, so that the bandage has high elasticity and high strength, is favorable for being worn at any part of a human body and is not easy to deform. Tests show that the base film spun at a polyurethane concentration of 14wt%, an electrostatic loading voltage of 22kv, a collection distance of 20cm, and a jet velocity of 0.2mL/h performs best. The addition of the nano silver particles enables the bandage to have antibacterial capacity, silver ions enter the interior of bacteria to destroy inherent components of the bacteria to cause the bacteria to die, the effect of fundamentally removing the bromhidrosis is achieved, and tests show that the antibacterial effect of the bandage is the best when the concentration of silver nitrate is 1.0 wt%.

The foregoing shows and describes the general principles and features of the present invention, together with the advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. A preparation method of a wearable sports bandage for removing bromhidrosis is characterized by comprising the following steps:

(1) dissolving polyurethane in a tetrahydrofuran and N, N-dimethylformamide blending solvent, magnetically stirring at 40-50 ℃ until a uniform and stable polyurethane solution is obtained, and then preparing a polyurethane nanofiber membrane with the thickness of 20-100 microns by an electrostatic spinning method;

(2) dissolving micron-sized beta-cyclodextrin and silicon dioxide in an N, N-dimethylformamide solvent, performing ultrasonic stirring for 1-2 hours and magnetic stirring until the solution is uniform and stable, and then performing electrostatic spraying on the polyurethane nanofiber membrane prepared in the step (1) to form a microsphere layer to obtain a composite membrane;

(3) adding silver nitrate into ammonia water, uniformly mixing, putting into a microwave reactor for reduction reaction to generate a nano silver particle solution with an antibacterial effect, immediately cooling to room temperature after complete reaction, soaking the composite membrane prepared in the step (2) into the nano silver particle solution for 2 hours, taking out and drying to obtain the wearable sports bandage for removing the bromhidrosis;

the molecular weight of the polyurethane in the step (1) is 33600, and the concentration of the polyurethane solution is 14 wt%; the mass ratio of tetrahydrofuran to N, N-dimethylformamide in the blending solvent is 1: 1;

in the step (1), the spinning temperature is 30 ℃, and the spinning humidity is 35-40%;

in the step (1), the electrostatic spinning loading voltage is 22kv, the collection distance is 20cm, and the jet velocity is 0.2 ml/h;

the mass ratio of the beta-cyclodextrin to the N, N-dimethylformamide in the step (2) is 1: 5;

in the step (2), the addition amount of silicon dioxide is 1wt% and the diameter of the silicon dioxide is 20nm, based on the mass of the beta-cyclodextrin;

in the step (2), the electrostatic spraying parameters are that the loading voltage is 24kv, the collection distance is 22cm, and the jet velocity is 0.06 ml/h.

2. The method for preparing wearable sports bandage for removing body odor according to claim 1, wherein: the concentration of the silver nitrate in the step (3) is 0.5-1 wt%.

3. The method for preparing wearable sports bandage for removing body odor according to claim 1, wherein: and (4) in the step (3), the power of the microwave reactor is 300-600W.

4. The method for preparing wearable sports bandage for removing body odor according to claim 1, wherein: the drying in the step (3) is drying in an oven at 80 ℃ for 24 hours.