CN110122887A - Improve the dietary fiber chewable tablets and preparation method thereof of gastrointestinal function - Google Patents
Improve the dietary fiber chewable tablets and preparation method thereof of gastrointestinal function Download PDFInfo
- Publication number
- CN110122887A CN110122887A CN201910477188.1A CN201910477188A CN110122887A CN 110122887 A CN110122887 A CN 110122887A CN 201910477188 A CN201910477188 A CN 201910477188A CN 110122887 A CN110122887 A CN 110122887A
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- CN
- China
- Prior art keywords
- parts
- dietary fiber
- powder
- stachyose
- chewable tablets
- Prior art date
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- Pending
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Classifications
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
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- A—HUMAN NECESSITIES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
- A23L33/22—Comminuted fibrous parts of plants, e.g. bagasse or pulp
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- A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
- A23L7/10—Cereal-derived products
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract
The invention discloses a kind of dietary fiber chewable tablets and preparation method thereof for improving gastrointestinal function, it include: 250-350 parts of soybean dietary fiber, 200-300 parts of quinoa rice, 150-250 parts of stachyose, 100-200 parts of hericium erinaceum polysaccharide, 50-150 parts of pollen pini, 4-6 parts of magnesium stearate, and according to the property of raw material, different disposal is respectively adopted, then final products are prepared；The present invention by soybean dietary fiber, stachyose, hericium erinaceum polysaccharide, with beta glucan in quinoa rice, protein plays synergistic effect in pollen pini; it compares one-component and preferably promotes enterogastric peristalsis; alleviate constipation; improve intestinal flora; furthermore; its nutritional ingredient is high; mineral matter element and amino acid rich in a variety of needed by human body; it can be while promoting enterogastric peristalsis; on the one hand it nourishes; on the other hand protection stomach, functional caused by preventing stomach from wriggling because of extraneous excessively fierce stimulation.
Description
Technical field
The present invention relates to improve gastrointestinal function field of health care food.It is more particularly related to a kind of improvement stomach and intestine
Dietary fiber chewable tablets of function and preparation method thereof.
Background technique
Existing improvement gastrointestinal function health food, mostly using simple dietary fiber as main component, existing improvement stomach and intestine
The meal fiber tablet ingredient of road function is essentially domperidone, digestive ferment or the Chinese medicine of stomach invigorating, such as hawthorn, malt, edible
Essence etc..Its raw material sources is single, generally chemical synthesis class drug or Chinese herbal and crude drugs preparations, be used for a long time can body to people and
Stomach causes great burden, and there are also some digestion-promoting stomachics using hawthorn, malt etc., although can be aid digestion, its sugar content
It is higher, it is not appropriate for diabetic's use；In addition, it is existing improve gastrointestinal function health care product only serve it is digestant,
It has a single function, nutritional ingredient is simple, and does not play a protective role to stomach when in use, the long-term high load capacity effect meeting pair of stomach
Gastrointestinal tract causes functional.In addition to this, the existing health food dosage form for improving gastrointestinal function is mostly with granule or pulvis
Based on, warm water delivery service is needed, edible inconvenience is carried, is unfavorable for nourishing at any time.How to develop it is a kind of natural, stomach and intestine can be improved
Function and full of nutrition carries and feeds the problem of convenient diet fiber health-care product are this field related personnel's urgent need to resolve.
Summary of the invention
It is an object of the invention to solve at least the above problems, and provide a kind of dietary fiber nozzle for improving gastrointestinal function
Piece and preparation method thereof is chewed, beta glucan, preserved egg in soybean dietary fiber, stachyose, hericium erinaceum polysaccharide and quinoa rice are passed through
Protein plays synergistic effect in powder, compares one-component and preferably promotes enterogastric peristalsis, alleviates constipation, improves intestinal flora,
In addition, its nutritional ingredient is high, mineral matter element and amino acid rich in a variety of needed by human body can be while promoting enterogastric peristalsis
On the one hand it nourishes, on the other hand protects stomach, functional damage caused by preventing stomach from wriggling because of extraneous excessively fierce stimulation
Wound.
In order to realize these purposes and other advantages according to the present invention, it is fine to provide a kind of diet for improving gastrointestinal function
Tie up chewable tablets, comprising: soybean dietary fiber, quinoa rice, stachyose, hericium erinaceum polysaccharide, pollen pini, magnesium stearate.
Preferably, the specific parts by weight of raw material are as follows: 250-350 parts of soybean dietary fiber, 200-300 parts of quinoa rice,
150-250 parts of stachyose, 100-200 parts of hericium erinaceum polysaccharide, 50-150 parts of pollen pini, 4-6 parts of magnesium stearate.
Preferably, the specific parts by weight of raw material are as follows: 300 parts of soybean dietary fiber, 250 parts of quinoa rice, stachyose 200
Part, 150 parts of hericium erinaceum polysaccharide, 100 parts of pollen pini, 5 parts of magnesium stearate.
A kind of preparation method for the dietary fiber chewable tablets improving gastrointestinal function, comprising the following steps:
Step 1: the soybean dietary fiber of above-mentioned parts by weight meter and quinoa rice are baked respectively, then by soybean dietary
Fiber and quinoa rice crush respectively, and 60-100 mesh is crossed after crushing；
Step 2: the pollen pini of above-mentioned parts by weight meter is crushed, the sieve of 100 mesh or more is crossed, pollen pini fine powder is obtained；It will be above-mentioned
The stachyose and hericium erinaceum polysaccharide of parts by weight meter are milled respectively, cross 60-100 mesh respectively, obtain stachyose powder and Hericium erinaceus
Polysaccharide powder；Obtained stachyose powder, hericium erinaceum polysaccharide powder and pollen pini fine powder are mixed, soybean dietary is added
Fiber powder and quinoa rice flour, stirring, obtain mixed powder；
Step 3: mass fraction is added in the mixed powder that step 2 is obtained as the wetting of 75% ethanol solution, it is mixed
Uniformly, softwood is obtained, the wet particle of 16 purposes then is made in softwood, by particle drying to moisture≤5%, then crosses 14 mesh
Sieve；
Step 4: the magnesium stearate of above-mentioned parts by weight meter is added in the particle for the drying that step 3 obtains, it is uniformly mixed,
Tabletting is carried out according to the ratio of every 1g.
Preferably, it is 1:0.8-0.12 that mixed powder and mass fraction, which are the weight ratio of 75% ethyl alcohol, in step 3.
Preferably, pollen pini is crushed using the method for ultramicro grinding in step 2, is crossed 300-400 mesh and is obtained.
Preferably, the time of the ultramicro grinding is 20-40min, ratio of grinding media to material 1.5-4.5:1, ball size 8-12mm
With each half of ball of 10-14mm.
Preferably, in step 2, the stachyose milling, sieving, the operating environment temperature stirred are 25-35 DEG C.
Preferably, in step 2, the hericium erinaceum polysaccharide milling, sieving, the operating environment temperature stirred are 25-35
℃。
Preferably, the time that stachyose powder, hericium erinaceum polysaccharide powder and pollen pini fine powder are mixed in step 2
For 15min, soy bean edible fiber powder and quinoa rice flour are added, the time of mixing is 25min.
The present invention is include at least the following beneficial effects:
The first, product formula is novel, and effect is obvious, acts synergistically between multicomponent, while promoting intestines peristalsis, energy
It protects gastric mucosa, promote stomach and intestine blood circulation, it is small to the burden of stomach compared to existing Domperidone class stomach medicine；
The second, each component also contains various trace elements other than collaboration is aid digestion, full of nutrition, after adjusting
It supplements the nutrients again, traditional sucrose, maltose etc. is replaced using stachyose, it not only can be aid digestion, moreover it is possible to enhance the pleased of eater
Happy sense, catharsis and toxin expelling not will increase the blood-sugar content of diabetic but also right not only so that diabetic is also able to use
The blood glucose of diabetic has certain control effect；
Different disposal is respectively adopted according to feedstock property in third, entire technique, is conducive to the holding of effective component, makes each original
The function of material obtains optimal performance, enhances product quality；Wherein, soybean dietary fiber, quinoa rice are baked using oven, favorably
In the formation of fragrance；Pollen pini obtains pollen pini fine powder using pulverizing, and is conducive to the absorption and active holding of ingredient；
It is directly mixed after stachyose, hericium erinaceum polysaccharide milling, and the treatment temperature of the two and processing time carry out strict control, can prevent wood
Sugar, hericium erinaceum polysaccharide brown stain, and keep its activity；Mixing sequence is using most raw materials as base-material, and other a small amount of auxiliary materials are to base-material
In mix, be easier to mix, be conducive to the stabilization of product quality；
Four, existing common granule or pulvis are replaced using this dosage form of chewable tablets, so that product carries edible side
Just, conducive to nourishing at any time.
Further advantage, target and feature of the invention will be partially reflected by the following instructions, and part will also be by this
The research and practice of invention and be understood by the person skilled in the art.
Specific embodiment
The present invention will be further described in detail below with reference to the embodiments, to enable those skilled in the art referring to specification
Text can be implemented accordingly.
<embodiment 1>
A kind of dietary fiber chewable tablets improving gastrointestinal function, specific raw material are as follows: soybean dietary fiber 250
Part, 200 parts of quinoa rice, 150 parts of stachyose, 100 parts of hericium erinaceum polysaccharide, 50 parts of pollen pini, 4 parts of magnesium stearate；
It is specific the preparation method comprises the following steps:
Step 1: the soybean dietary fiber of above-mentioned parts by weight meter and quinoa rice are baked respectively, bake using face fire
It 180 DEG C, 150 DEG C of the fire in a stove before fuel is added, time 35min, bakes to faint yellow, then crushes, cross 60 meshes, it is spare；
Step 2: the pollen pini of above-mentioned parts by weight meter is crushed, the sieve of 100 mesh is crossed, pollen pini fine powder is obtained；By above-mentioned weight
The stachyose and hericium erinaceum polysaccharide of part meter are milled respectively, cross 60 meshes respectively, obtain stachyose powder and hericium erinaceum polysaccharide powder；
By obtained stachyose powder, hericium erinaceum polysaccharide powder and pollen pini fine powder be mixed, add soy bean edible fiber powder and
Quinoa rice flour, stirring, obtains mixed powder；
Step 3: in the mixed powder that step 2 is obtained be added mass fraction be 75% ethanol solution soak, mixed powder and
Mass fraction is that the weight ratio of 75% ethyl alcohol is that 1:0.12 is mixed evenly, and obtains softwood, softwood is then made 16
Then particle drying to moisture≤5% is crossed 14 meshes by the wet particle of purpose；
Step 4: the magnesium stearate of above-mentioned parts by weight meter is added in the particle for the drying that step 3 obtains, it is uniformly mixed,
Tabletting is carried out according to the ratio of every 1g.
<embodiment 2>
A kind of dietary fiber chewable tablets improving gastrointestinal function, specific raw material are as follows: soybean dietary fiber 350
Part, 300 parts of quinoa rice, 250 parts of stachyose, 200 parts of hericium erinaceum polysaccharide, 150 parts of pollen pini, 6 parts of magnesium stearate；
It is specific the preparation method comprises the following steps:
Step 1: the soybean dietary fiber of above-mentioned parts by weight meter and quinoa rice are baked respectively, bake using face fire
It 180 DEG C, 150 DEG C of the fire in a stove before fuel is added, time 35min, bakes to faint yellow, then crushes, sieve with 100 mesh sieve, it is spare；
Step 2: the pollen pini of above-mentioned parts by weight meter is crushed, using the method for ultramicro grinding, the time of ultramicro grinding is
20min, ratio of grinding media to material 1.5:1, each half of ball of ball size 8-12mm and 10-14mm cross the sieve of 300 mesh, obtain pollen pini fine powder；
The stachyose of above-mentioned parts by weight meter and hericium erinaceum polysaccharide are milled respectively, sieved with 100 mesh sieve respectively, stachyose powder and hedgehog hydnum are obtained
Mushroom polysaccharide powder；15min is mixed in obtained stachyose powder, hericium erinaceum polysaccharide powder and pollen pini fine powder, is added
Soy bean edible fiber powder and quinoa rice flour stir 25min, obtain mixed powder；Wherein, stachyose milling and hericium erinaceum polysaccharide milling
When sieving operation, environment temperature is 25 DEG C；
Step 3: in the mixed powder that step 2 is obtained be added mass fraction be 75% ethanol solution soak, mixed powder and
Mass fraction is that the weight ratio of 75% ethyl alcohol is 1:0.8, is mixed evenly, obtains softwood, softwood is then made 16
Then particle drying to moisture≤5% is crossed 14 meshes by the wet particle of purpose；
Step 4: the magnesium stearate of above-mentioned parts by weight meter is added in the particle for the drying that step 3 obtains, it is uniformly mixed,
Tabletting is carried out according to the ratio of every 1g.
<embodiment 3>
A kind of dietary fiber chewable tablets improving gastrointestinal function, specific raw material are as follows: soybean dietary fiber 300
Part, 250 parts of quinoa rice, 200 parts of stachyose, 150 parts of hericium erinaceum polysaccharide, 100 parts of pollen pini, 5 parts of magnesium stearate；
It is specific the preparation method comprises the following steps:
Step 1: the soybean dietary fiber of above-mentioned parts by weight meter and quinoa rice are baked respectively, bake using face fire
It 180 DEG C, 150 DEG C of the fire in a stove before fuel is added, time 35min, bakes to faint yellow, then crushes, cross 80 meshes, it is spare；
Step 2: the pollen pini of above-mentioned parts by weight meter is crushed, using the crushing of the method for ultramicro grinding, the time of ultramicro grinding is
40min, ratio of grinding media to material 4.5:1, each half of ball of ball size 8-12mm and 10-14mm cross the sieve of 400 mesh, obtain pollen pini fine powder；
The stachyose of above-mentioned parts by weight meter and hericium erinaceum polysaccharide are milled respectively, sieved with 100 mesh sieve respectively, stachyose powder and hedgehog hydnum are obtained
Mushroom polysaccharide powder；15min is mixed in obtained stachyose powder, hericium erinaceum polysaccharide powder and pollen pini fine powder, is added
Soy bean edible fiber powder and quinoa rice flour stir 25min, obtain mixed powder；Wherein, stachyose milling and hericium erinaceum polysaccharide milling
When sieving operation, environment temperature is 25 DEG C；
Step 3: in the mixed powder that step 2 is obtained be added mass fraction be 75% ethanol solution soak, mixed powder and
Mass fraction is that the weight ratio of 75% ethyl alcohol is 1:0.8, is mixed evenly, obtains softwood, softwood is then made 16
Then particle drying to moisture≤5% is crossed 14 meshes by the wet particle of purpose；
Step 4: the magnesium stearate of above-mentioned parts by weight meter is added in the particle for the drying that step 3 obtains, it is uniformly mixed,
Tabletting is carried out according to the ratio of every 1g.
<embodiment 4>
A kind of dietary fiber chewable tablets improving gastrointestinal function, specific raw material are as follows: soybean dietary fiber 300
Part, 250 parts of quinoa rice, 200 parts of stachyose, 150 parts of hericium erinaceum polysaccharide, 100 parts of pollen pini, 5 parts of magnesium stearate；
It is specific the preparation method comprises the following steps:
Step 1: the soybean dietary fiber of above-mentioned parts by weight meter and quinoa rice are baked respectively, bake using face fire
It 180 DEG C, 150 DEG C of the fire in a stove before fuel is added, time 35min, bakes to faint yellow, then crushes, cross 80 meshes, it is spare；
Step 2: the pollen pini of above-mentioned parts by weight meter is crushed, using the method for ultramicro grinding, the time of ultramicro grinding is
40min, ratio of grinding media to material 3:1, each half of ball of ball size 8-12mm and 10-14mm cross the sieve of 350 mesh, obtain pollen pini fine powder；It will
The stachyose and hericium erinaceum polysaccharide of above-mentioned parts by weight meter are milled respectively, sieve with 100 mesh sieve respectively, obtain stachyose powder and Hericium erinaceus
Polysaccharide powder；15min is mixed in obtained stachyose powder, hericium erinaceum polysaccharide powder and pollen pini fine powder, is added big
Beans food fibre powder and quinoa rice flour stir 25min, obtain mixed powder；Wherein, stachyose milling and hericium erinaceum polysaccharide were milled
When sieve operation, environment temperature is 25 DEG C；
Step 3: in the mixed powder that step 2 is obtained be added mass fraction be 75% ethanol solution soak, mixed powder and
Mass fraction is that the weight ratio of 75% ethyl alcohol is 1:0.8, is mixed evenly, obtains softwood, softwood is then made 16
Then particle drying to moisture≤5% is crossed 16 meshes by the wet particle of purpose；
Step 4: the magnesium stearate of above-mentioned parts by weight meter is added in the particle for the drying that step 3 obtains, it is uniformly mixed,
Tabletting is carried out according to the ratio of every 1g.
<comparative example 1>
Only with two kinds of raw materials of soybean dietary fiber and magnesium stearate, and parts by weight are same as Example 3, preparation method
It is same as Example 3.
<comparative example 2>
Only with two kinds of raw materials of stachyose and magnesium stearate, and parts by weight are same as Example 3, preparation method and implementation
Example 3 is identical.
<comparative example 3>
Only with two kinds of raw materials of pollen pini and magnesium stearate, and parts by weight are same as Example 3, preparation method and implementation
Example 3 is identical.
Experimental example:
One, nutrient composition content
The product of Example 3 carries out nutritional ingredient detection
Conventional nutrients measurement
Determination of moisture: atmosphere pressure desiccation, referring to GB/T 5009.3-2003 (the first method).
Crude fat measurement: soxhlet extraction, referring to GB/T 5009.6-2003.
Total protein measurement: constant Kjeldahl's method, referring to GB/T 5009.5-2003 (the first method).
Ash determination: GB/T5009.4-2003.
Mineral element measurement
Copper is referring to GB/T 5009.13-2003 (the first method).Zinc is referring to GB/T 5009.14-2003 (the first method).Phosphorus ginseng
According to GB/T 5009.87-2003 (the first method).Magnesium, iron, manganese are referring to GB/T 5009.90-2003.Potassium, sodium are referring to GB/
T5009.91-2003.Calcium is referring to GB/T 5009.92-2003 atomic absorption spectrophotometry.Selenium is referring to GB/T 5009.93-
2003 (the first methods).
Table 1, conventional nutrients content (g/100g dry weight)
| Ash content | Protein | Fat | Total carbohydrates | Total dietary fiber |
| 2.490 | 5.312 | 3.777 | 88.421 | 29.808 |
Table 2, content of mineral substances (mg/100g dry weight)
| Potassium | Sodium | Calcium | Magnesium | Copper | Zinc | Iron | Manganese | Selenium | Phosphorus |
| 436.17 | 5.89 | 73.37 | 137.16 | 0.226 | 0.86 | 7.78 | 0.91 | 3.79 | 54.91 |
From Tables 1 and 2 comparison " Chinese food nutrient component meter 2004 " as can be seen that the total dietary fiber of this product
Height, fat content is low, and protein content is high, is also rich in multi mineral prime element, has compared to the product of market more
Nutritional ingredient, can not only improve gastrointestinal function, but also the supplement of nutrition can be carried out to eater, play the work of protection stomach
With, prevent stomach because external environment excessively promote wriggle caused by functional.
Two, improve gastrointestinal function experiment
Purpose: by improving the dietary fiber chewable tablets of gastrointestinal function to Rats with Spleen-deficiency gastric emptying rate, Plasma Motilin Levels and Colonic Motility
It influences, inquires into influence of the dietary fiber chewable tablets for improving gastrointestinal function to spleen and stomach function.
Sample: respectively Example 3, comparative example 1, comparative example 2, comparative example 3 chewable tablets as sample, administration group is made
Medicament and number.
Method: by each administration group to SD rat (this experimental animal Technology Co., Ltd. ticket number of Changchun hundred million: SCXK
(Ji) -2016-0003) stomach-filling is carried out, in addition to blank group, the big yellow liquor (3mL/kg/ days × 15 days) that remaining each group fills 200% is made
Model of spleen deficiency, continuous 15 days, blank group and model group continued to pour water from the 16th day, and administration group fills 10 times of people's dosage (160mg/
Kg/ days × 30 days), at the 31st day, influence of the observation wine liquid to spleen deficiency test rat gastric emptying rate, Plasma Motilin Levels and Colonic Motility respectively, was shown in Table
3。
After last dose 40min, 2000 solution of glucan blue BD (20mg/mL) 0.4mL stomach-filling is given, cervical vertebra is de- after 20min
Mortar is put to death, and cuts open the belly take full stomach rapidly, cut off along greater curvature side, its content is dissolved in 4mL distilled water, 3500r/min centrifugation
15min takes supernatant ultraviolet-uisible spectrophotometer to survey absorbance at 620nm, is calculated as A value；Take same concentrations BD 2000
Solution 0.4mL is centrifuged under the same terms, is taken supernatant to survey absorbance value, is calculated as B value.Take rat small intestine rapidly simultaneously, measurement is complete
Intestines distance and 2000 solution enteral advance distance of BD.
After the last administration in rat eye socket blood sampling 2mL, after standing condensation, 15 DEG C of centrifugation 10min of 3000r/min take supernatant
Liquid sets the standby inspection of -80 DEG C of refrigerators, with motilin in the method detection rat blood serum of radio-immunity.
Data are indicated with average ± standard deviation (X ± SD), handle test data using SPSS software.
Gastric emptying rate calculation formula: (B-A)/B × 100%；
Intestinal propulsive rate calculation formula: enteral advance distance (cm)/small intestinal length (cm) × 100%.
Table 3, dietary fiber chewable tablets to rat gastric emptying rate, motilin, Intestinal propulsive rate level influence (n=10, X
±SD)
| Group | Gastric emptying rate (%) | Motilin (pg/mL) | Intestinal propulsive rate (%) |
| Blank group | 80.30±10.10 | 231.11±20.65 | 86.88±7.56 |
| Model group | 60.31±9.01▲▲ | 175.39±20.45▲▲ | 66.19±9.88▲▲ |
| Embodiment 3 | 75.67±9.88★★ | 213.64±19.33★★ | 79.93±9.93★★ |
| Comparative example 1 | 73.37±5.78★★ | 184.65±16.28★ | 72.73±3.63★ |
| Comparative example 2 | 67.09±1.87★ | 180.21±17.13★ | 70.55±2.18★ |
| Comparative example 3 | 65.59±4.55★ | 181.66±16.65★ | 72.62±4.25★ |
Note: compared with blank group▲P < 0.05,▲▲p<0.01；Compared with model group★P < 0.05,★★p<0.01。
As a result: model group and blank group comparing difference highly significant, gastric emptying rate, the blood plasma stomach of model of spleen deficiency rat are dynamic
Element, Intestinal propulsive rate level significantly reduce, and affect the normal stool function of taste.It is observed that embodiment 3, comparative example 1,
Comparative example 2 and comparative example 3, gastric emptying rate, plasma motilin and Intestinal propulsive rate are restored compared with than model group, but real
The effect for applying example 3 is more preferable compared with comparative example 1-3.The dietary fiber chewable tablets group of embodiment 3 is by increasing Plasma Motilin Levels and Colonic Motility water
It puts down and improves stomach function, motilin levels, gastric emptying rate, Intestinal propulsive rate are noticeably greater than model group (p < 0.01), to mention
The high digestion of stomach and intestine, absorption, the function of transporting nutrition goods and materials and moisture, at the same time, embodiment 1, embodiment 2 and embodiment
4 carried out relevant experiment, and all showed the preferable normal stool function of improving gastrointestinal function and do not influence taste,
But embodiment 3 is optimal example, therefore only provides the data of embodiment 3.
Conclusion: the adjustable Rats with Spleen-deficiency blood plasma motilin of dietary fiber chewable tablets reinforces the gastric emptying rate of Rats with Spleen-deficiency
And Intestinal propulsive rate, and then enhance gastrointestinal function, adjust gastro-intestinal digestion absorption function.It can be seen that dietary fiber chewable tablets are true
In fact play the role of improve gastrointestinal function, and the multiple efficacies in dietary fiber chewable tablets at subassembly compared with being administered alone group
With better effect, illustrate soybean dietary fiber, stachyose, hericium erinaceum polysaccharide, in beta glucan in quinoa rice, pollen pini
The effect of protein plays synergistic effect, preferably plays promotion enterogastric peristalsis, alleviates constipation, improves intestinal flora.Three, to II
Patients with type Ⅰ DM mouse blood sugar adjusts experiment
Purpose: by chewable tablets to type II diabetes mouse fasting blood-glucose, serum insulin, insulin resistance index, liver
The effect that chewable tablets adjusts type II diabetes mouse blood sugar is probed into the detection of the indexs such as glycogen.
Sample: the chewable tablets that 3 groups of Example is detected as sample.
Method: press 10 times of people's dosage, to type II diabetes mouse (model animal research institute, Nanjing University, ticket number:
SYXK (Soviet Union) 2018-0027) stomach-filling, mouse is divided into model group, dietary fiber chewable tablets group (160mg/kg/ days), diet is fine
Dimension is deprived of food but not water after the stomach-filling of chewable tablets group 30 days, and second day, eyeball took blood, takes liver, carries out fasting blood-glucose, serum islet
The measurement of element, insulin resistance index, hepatic glycogen.
Data are indicated with average ± standard deviation (X ± SD), handle test data using SPSS software.
Specific blood glucose target analysis is shown in Table 4.
Table 4, blood glucose target analysis
| Model group | Dietary fiber chewable tablets group | |
| Fasting blood-glucose | 22.50±0.967 | 20.37±0.991* |
| Serum insulin | 14.29±0.176 | 13.91±0.145* |
| Insulin resistance index | 6.35±0.424 | 5.82±0.351* |
| Hepatic glycogen | 2.09±0.548 | 2.37±0.654 |
Note: p < 0.01 * p < 0.05 compared with model group, * *.
As shown in table 4, after intervening 30 days, compared with model group, the dietary fiber chewable tablets group mouse fasting blood of embodiment 3
Sugar, serum insulin, insulin resistance index have reduction, significant difference (p < 0.05), and hepatic glycogen level has increase, each index
There is preferable improvement, at the same time, embodiment 1, embodiment 2 carried out relevant experiment to embodiment 4, and all showed
The level of preferable blood glucose-control, but embodiment 3 is optimal example, therefore only provides the data of embodiment 3.
To sum up, the dietary fiber chewable tablets for improving gastrointestinal function can also preferably adjust the blood glucose of type II diabetes mouse and refer to
Mark.
Four, influence of the preserved egg Powder Particle Size to its component content
Common composition content measuring method:
Crude fat measurement: soxhlet extraction, referring to GB/T 5009.6-2003.
Protein determination: constant Kjeldahl's method, referring to GB/T 5009.5-2003 (the first method).
Influence (X ± SD) of the 5 preserved egg Powder Particle Size of table to its component content
Influence of the granularity to active constituent after pollen pini pulverizes has been probed into test (table 5), it is determined that pollen pini is best
Granularity.The result shows that pollen pini pulverize with routinely crush compared with, nutrient composition content improve, wherein crude protein content from
12.7g increasing to 13.1g；Total rouge increases to 10.0g from 7.3g；Carbohydrate increases to 30.2g from 14.8g；Crude fibre from
27.3g increasing to 35.6g.Illustrate that the variation of granularity after ultramicro crushing treatment has an impact to its ingredient, in the product routinely crushed
Position partial size is 5.893 μm, and partial size is 5.187 μm in the product of ultramicro grinding, is more advantageous to absorption of human body.
Although the embodiments of the present invention have been disclosed as above, but its is not only in the description and the implementation listed
With it can be fully applied to various fields suitable for the present invention, for those skilled in the art, can be easily
Realize other modification, therefore without departing from the general concept defined in the claims and the equivalent scope, the present invention is simultaneously unlimited
In specific details and embodiment shown and described herein.
Claims (10)
1. improving the dietary fiber chewable tablets of gastrointestinal function, which is characterized in that including following raw material: soybean dietary fiber, quinoa
Rice, stachyose, hericium erinaceum polysaccharide, pollen pini, magnesium stearate.
2. improving the dietary fiber chewable tablets of gastrointestinal function as described in claim 1, which is characterized in that the specific weight of raw material
Measure part are as follows: 250-350 parts of soybean dietary fiber, 200-300 parts of quinoa rice, 150-250 parts of stachyose, hericium erinaceum polysaccharide 100-
200 parts, 50-150 parts of pollen pini, 4-6 parts of magnesium stearate.
3. improving the dietary fiber chewable tablets of gastrointestinal function as claimed in claim 2, which is characterized in that the specific weight of raw material
Number are as follows: 300 parts of soybean dietary fiber, 250 parts of quinoa rice, 200 parts of stachyose, 150 parts of hericium erinaceum polysaccharide, 100 parts of pollen pini,
5 parts of magnesium stearate.
4. improving the preparation method of the dietary fiber chewable tablets of gastrointestinal function as described in claim 1, which is characterized in that including
Following steps:
Step 1: the soybean dietary fiber of above-mentioned parts by weight meter and quinoa rice are baked respectively, then by soybean dietary fiber
It is crushed respectively with quinoa rice, 60-100 mesh is crossed after crushing；
Step 2: the pollen pini of above-mentioned parts by weight meter is crushed, the sieve of 100 mesh or more is crossed, pollen pini fine powder is obtained；By above-mentioned weight
The stachyose and hericium erinaceum polysaccharide of part meter are milled respectively, cross 60-100 mesh respectively, obtain stachyose powder and hericium erinaceum polysaccharide
Powder；Obtained stachyose powder, hericium erinaceum polysaccharide powder and pollen pini fine powder are mixed, soybean dietary fiber is added
Powder and quinoa rice flour, stirring, obtain mixed powder；
Step 3: mass fraction is added in the mixed powder that step 2 is obtained as the wetting of 75% ethanol solution, it is mixed evenly,
Softwood is obtained, the wet particle of 16 purposes then is made in softwood, by particle drying to moisture≤5%, then crosses 14 meshes；
Step 4: the magnesium stearate of above-mentioned parts by weight meter is added in the particle for the drying that step 3 obtains, it is uniformly mixed, according to
The ratio of every 1g carries out tabletting.
5. improving the preparation method of the dietary fiber chewable tablets of gastrointestinal function as claimed in claim 4, which is characterized in that step
It is 1:0.8-0.12 that mixed powder and mass fraction, which are the weight ratio of 75% ethyl alcohol, in three.
6. improving the preparation method of the dietary fiber chewable tablets of gastrointestinal function as claimed in claim 4, which is characterized in that step
Pollen pini is crushed using the method for ultramicro grinding in two, is crossed 300-400 mesh and is obtained.
7. improving the preparation method of the dietary fiber chewable tablets of gastrointestinal function as claimed in claim 6, which is characterized in that described
The time of ultramicro grinding is 20-40min, ratio of grinding media to material 1.5-4.5:1, each half of ball of ball size 8-12mm and 10-14mm.
8. improving the preparation method of the dietary fiber chewable tablets of gastrointestinal function as claimed in claim 4, which is characterized in that step
In two, the stachyose milling, sieving, the operating environment temperature stirred are 25-35 DEG C.
9. improving the preparation method of the dietary fiber chewable tablets of gastrointestinal function as claimed in claim 4, which is characterized in that step
In two, the hericium erinaceum polysaccharide milling, sieving, the operating environment temperature stirred are 25-35 DEG C.
10. improving the preparation method of the dietary fiber chewable tablets of gastrointestinal function as claimed in claim 4, which is characterized in that step
The time that stachyose powder, hericium erinaceum polysaccharide powder and pollen pini fine powder are mixed in rapid two is 15min, adds soybean meals
Eating the time that fiber powder and quinoa rice flour are mixed is 25min.
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