CN110108533A - Tissue processor - Google Patents

Tissue processor Download PDF

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Publication number
CN110108533A
CN110108533A CN201910439241.9A CN201910439241A CN110108533A CN 110108533 A CN110108533 A CN 110108533A CN 201910439241 A CN201910439241 A CN 201910439241A CN 110108533 A CN110108533 A CN 110108533A
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CN
China
Prior art keywords
valve
paraffin
annular
quiet
reagent
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Granted
Application number
CN201910439241.9A
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Chinese (zh)
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CN110108533B (en
Inventor
葛永平
唐海涛
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CHANGZHOU PAISIJIE MEDICAL EQUIPMENT Co Ltd
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CHANGZHOU PAISIJIE MEDICAL EQUIPMENT Co Ltd
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Priority to CN201910439241.9A priority Critical patent/CN110108533B/en
Publication of CN110108533A publication Critical patent/CN110108533A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Multiple-Way Valves (AREA)

Abstract

The present invention relates to a kind of tissue processor, including body, reagent tank group, paraffin cylinder group, working chamber and fluid path switching valve are provided on the body, the working chamber is connected between reagent tank group and paraffin cylinder group respectively through fluid path switching valve;The interior valve road that is equipped with of the fluid path switching valve switches datum level, and the valve road switching datum level is on body highly higher than the highest work liquid level in reagent tank group, paraffin cylinder group, working chamber.Fluid path switching valve installation site is higher than to the highest liquid level of paraffin cylinder and working chamber liquid.When valve body is higher than the paraffin liquid level of paraffin cylinder, paraffin in cylinder avoids paraffin in the intracorporal leakage of valve there is no need to seal for a long time by valve.After entering working chamber, the liquid in working chamber does not need to seal anti-backflow by valve same liquid yet, avoids leakage of the liquid in valve, improves the type reliable for operation of complete machine.

Description

Tissue processor
Technical field
The present invention relates to a kind of tissue processors.
Background technique
Tissue processor to human body or animal vegetable tissue automatically by program immerse various solvents be dehydrated, transparent, waxdip Equal pathological analysis pre-treatment, is suitable for medical colleges and schools, hospital pathology department, medical research unit, animals and plants R&D institution and food The departments laboratories such as detection use.
It include multiple reagent chambers, paraffin chamber and working chamber, installation fluid path conversion in tissue processor in tissue processor Valve is connected to working chamber successively with each reagent chamber and paraffin chamber by fluid path switching valve;When working chamber is needed into examination When agent, working chamber is made to keep negative pressure, is then connected to corresponding reagent chamber by fluid path switching valve, when working chamber need into When paraffin, it is connected to by fluid path switching valve with corresponding paraffin chamber.
Fluid path switching valve in previous dewaterer is easy to appear leakage, and the reagent and paraffin of individual channel will appear micro Leakage, to find out its cause, first is that fluid path switching valve structural design is unreasonable, second is that fluid path switching valve installation position in dewaterer Set unreasonable, installation site of the previous fluid path switching valve on dewaterer is lower than working chamber and paraffin chamber, when existing in working chamber When reagent, there can be difference in height between reagent highest order and switching valve, this difference in height can make switching valve bear reagent Pressure, so that fluid path switching valve be caused to be easy leakage.
Summary of the invention
The technical problem to be solved by the present invention is overcome the deficiencies of the prior art and provide a kind of tissue processor, solve with The problem of fluid path switching valve is easily revealed into dewaterer.
The technical solution adopted by the present invention to solve the technical problems is: a kind of tissue processor, including body, the machine Be provided with reagent tank group, paraffin cylinder group, working chamber and fluid path switching valve on body, the working chamber through fluid path switching valve respectively with It is connected between reagent tank group and paraffin cylinder group;
It is equipped with valve road in the fluid path switching valve and switches datum level, the valve road switching datum level is highly higher than reagent on body Cylinder group, paraffin cylinder group, the highest in working chamber work liquid level.
Further, the fluid path switching valve includes valve body and mistake axle assemble;
Total access and multiple tributary circuits are opened up on the valve body, the valve body upper surface is equipped with the quiet valve face of annular, respectively The outlet of a tributary circuit is provided with respectively on the quiet valve face of annular, and the import of total access is provided at the quiet valve face center of annular Valve body on;
Described cross is equipped with gap bridge access in axle assemble, the axle assemble of crossing includes inlet end and an outlet end, the gap bridge access Import is provided with input end, and the gap bridge lane exit is provided with outlet end, outlet end and the total access of the gap bridge access Import rotary seal connection, the input end for crossing axle assemble form dynamic valve face, the dynamic valve face and valve body for crossing axle assemble The quiet valve face of annular be slidingly sealed cooperation;
Contact surface between the dynamic valve face and the quiet valve face of annular is that the valve road switches datum level.
Further, the axle assemble of crossing includes mandrel and bridge shaft, is equipped with the first gap bridge channel, institute in the bridge shaft It states and is equipped with the second gap bridge channel in mandrel, the bridge shaft outlet end is sealedly and fixedly connected with mandrel input end, so that the first mistake Bridge channel is connected to the second gap bridge channel.
Further, the entrance of total access forms step installing port, and the step installing port is equipped with T shape axle sleeve, Rolling bearing, the mandrel lower end connection rolling bearing and T shape axle sleeve are provided on the T shape axle sleeve.
Further, valve chest is provided on the valve body, the shell that the axle assemble excessively is located at valve chest is intracavitary, described The upper end of mandrel passes through valve chest, and angle thrust bearing is provided between the mandrel and valve chest;The mandrel upper end is provided with Belt pulley, the percutaneous band connection motor of belt pulley.
Further, the bridge shaft includes horizontal axis and vertical pivot, and horizontal chamber is opened up in the horizontal axis, is opened up in the vertical pivot perpendicular Chamber, the perpendicular chamber are connected to horizontal chamber, and the horizontal chamber is connected to the second gap bridge channel;
The vertical pivot lower end is sleeved and fixed, and the fixing sleeve slides up and down seal-moving, the fixing sleeve in vertical pivot lower end Moving valve plate is fixedly installed in lower end, opens up valve opening on the moving valve plate, perforation, the moving valve plate lower end surface are opened up on the fixing sleeve The as described dynamic valve face, it is described erect it is intracavitary be provided with flexible adjustment mechanism so as to be fitted tightly over annular quiet for the dynamic valve face On valve face.
Further, the elastic adjusting mechanism includes adjusting screw, upper seal nipple, lower seal nipple and compression bullet Spring;The adjusting screw is screwed in vertical pivot upper end, and the upper seal nipple, lower seal nipple, which are located at, erects intracavitary, the compression bullet For spring between upper seal nipple and lower seal nipple, the lower seal nipple lower end abuts fixing sleeve.
Further, the valve port switch area of the valve body opens up annular groove, and ring is fixedly installed in the annular groove The quiet valve block of shape, the outlet of each tributary circuit are provided on the quiet valve block of annular, and the upper surface of the quiet valve block is described quiet Valve face.
Further, each tributary circuit is divided into several paraffin accesses, several reagent accesses and one change liquid access;
The quiet valve face of annular is divided into paraffin area and reagent area;
Each paraffin lane exit is provided with paraffin area, and the outlet of each reagent access and the outlet for changing liquid access are provided with Reagent area.
Further, overflow passage is opened up in the valve body, it is heavy to be formed on the valve body among the quiet valve block of annular Area drops, and the decanting zone height is provided on decanting zone lower than the quiet valve face of annular, the import of the overflow passage;
Radial overflow launder is opened up on the valve port switch area of paraffin area two sides respectively, the radial direction overflow launder connects decanting zone.
The beneficial effects of the present invention are:
A kind of dewaterer is provided, fluid path switching valve installation site is higher than to the highest liquid level of paraffin cylinder and working chamber liquid.Work as valve When body is higher than the paraffin liquid level of paraffin cylinder, paraffin in cylinder avoids paraffin in valve body there is no need to seal for a long time by valve Leakage.After entering working chamber, the liquid in working chamber does not need to seal anti-backflow by valve same liquid yet, avoids Leakage of the liquid in valve, improves the type reliable for operation of complete machine.
In fluid path switching valve moving valve plate by elastic adjusting mechanism can be stable be pressed on quiet valve face, promote dynamic valve face Contact leakproofness between quiet valve face prevents fluid path switching valve from leaking when switching fluid path.
Detailed description of the invention
The following further describes the present invention with reference to the drawings.
Fig. 1 is tissue processor's schematic diagram of the present invention;
Fig. 2 is the perspective view of switching valve of the present invention;
Fig. 3 is that switching valve removes schematic diagram after valve chest;
Fig. 4 is switching valve semi-cutaway;
Fig. 5 is bridge shaft sectional view;
Fig. 6 is valve body schematic diagram;
Fig. 7 is schematic diagram of the quiet valve block on valve body;
Fig. 8 is quiet valve block perspective view;
Fig. 9 is bridge shaft perspective view;
Wherein, 1, valve body, 1A, total access, 1B, overflow passage, 2, mandrel, 21, axle sleeve, 3, bridge shaft, 31, horizontal chamber, 32, perpendicular Chamber, 4, elastic adjusting mechanism, 41, upper seal nipple, 42, lower seal nipple, 43, compressed spring, 44, adjusting screw, 51, fixation Set, 52, moving valve plate, 61, valve chest, 62, motor, 7, quiet valve block, 71, paraffin access, 72, reagent access, 73, change liquid access, 74, radial overflow launder, 8, body, 81, paraffin chamber, 82, working chamber, A, valve road switch datum level, B, working chamber highest working solution Position, C, paraffin cylinder highest work liquid level.
Specific embodiment
Presently in connection with specific embodiment, the present invention is further illustrated.These attached drawings are simplified schematic diagram only with Illustration illustrates basic structure of the invention, therefore it only shows the composition relevant to the invention.
As shown in Figure 1, a kind of tissue processor, including body 8, reagent tank group, paraffin cylinder are provided on the body 8 Group, working chamber 82 and fluid path switching valve, working chamber 82 is interior to have working chamber highest work liquid level B, has paraffin in paraffin cylinder Cylinder highest work liquid level C, reagent cylinder position are lower than paraffin cylinder;The working chamber 82 through fluid path switching valve respectively with reagent tank group with And it is connected between paraffin cylinder group;It is equipped with valve road in the fluid path switching valve and switches datum level A, the valve road switching datum level A exists Highly higher than the highest work liquid level in reagent tank group, paraffin cylinder group, working chamber 82 on body 8.
Fluid path switching valve installation site is higher than to the highest liquid level of paraffin cylinder and working chamber liquid.When valve body is higher than paraffin cylinder Paraffin liquid level when, paraffin in cylinder avoids paraffin in the intracorporal leakage of valve there is no need to seal for a long time by valve.Same sample liquid After entering working chamber, the liquid in working chamber does not need to seal anti-backflow by valve body yet, avoids liquid in valve Leakage, improve the type reliable for operation of complete machine.
Specifically, being directed to fluid path switching valve, as shown in Fig. 2-Fig. 9, the fluid path switching valve includes valve body 1 and passes a bridge Component;Total access 1A and multiple tributary circuits are opened up on the valve body 1,1 upper surface of valve body is equipped with the quiet valve of annular Face, the outlet of each tributary circuit are provided with respectively on the quiet valve face of annular, and the import of total access 1A is provided with the quiet valve of annular On valve body 1 at the center of face.
It as shown in Fig. 4 Fig. 5, crosses and is equipped with gap bridge access in axle assemble, the axle assemble of crossing includes inlet end and an outlet end, institute The import for stating gap bridge access is provided with input end, and the gap bridge lane exit is provided with outlet end, the outlet of the gap bridge access End is connect with the import rotary seal of total access 1A, and the input end of the axle assemble excessively forms dynamic valve face, the axle assemble excessively The quiet valve face of annular of dynamic valve face and valve body 1 is slidingly sealed cooperation;Contact surface between the dynamic valve face and the quiet valve face of annular is Switch datum level A for the valve road.
Specifically, crossing axle assemble includes mandrel 2 and bridge shaft 3, the first gap bridge channel is equipped in the bridge shaft 3, it is described The second gap bridge channel is equipped in mandrel 2,3 outlet end of bridge shaft is sealedly and fixedly connected with 2 input end of mandrel, so that the first mistake Bridge channel is connected to the second gap bridge channel.
It is connected between first gap bridge channel, the connection of the second gap bridge channel and total access 1A, is connected according to the first gap bridge channel The corresponding reagent chamber or paraffin chamber 81 connect, realizes that it is connected to working chamber 82.
Specifically, the entrance of total access 1A forms step installing port, the step installing port is equipped with T shape axle sleeve 21, institute It states and is provided with rolling bearing on T shape axle sleeve 21, the mandrel lower end connection rolling bearing and T shape axle sleeve 21.
Meanwhile valve chest 61 is provided on the valve body 1, the shell that the axle assemble excessively is located at valve chest 61 is intracavitary, institute The upper end for stating mandrel 2 passes through valve chest 61, is provided with angle thrust bearing between the mandrel 2 and valve chest 61;On the mandrel 2 End is provided with belt pulley, the percutaneous band connection motor 62 of belt pulley.
Bearing is respectively set in the upper and lower ends of mandrel 2, improves the stability of the rotation of mandrel 2.Mandrel 2 is driven by motor 62 Turn is dynamic, and motor 62 drove axle assemble to rotate in 61 body of valve chest.
Specifically, bridge shaft 3 includes horizontal axis and vertical pivot, and horizontal chamber 31 is opened up in the horizontal axis, described perpendicular as shown in Fig. 4 Fig. 5 Perpendicular chamber 32 is opened up in axis, the perpendicular chamber 32 is connected to horizontal chamber 31, and the horizontal chamber 31 is connected to the second gap bridge channel;
The vertical pivot lower end is sleeved and fixed set 51, and the fixing sleeve 51 slides up and down seal-moving in vertical pivot lower end, described solid Surely 51 lower ends fixed setting moving valve plate 52 is covered, valve opening is opened up on the moving valve plate 52, perforation is opened up on the fixing sleeve 51, it is described 52 lower end surface of moving valve plate is the dynamic valve face, flexible adjustment mechanism is provided in the perpendicular chamber 32, so that the dynamic valve face It is fitted tightly on the quiet valve face of annular.
As shown in figure 5, the elastic adjusting mechanism 4 include adjust screw 44, upper seal nipple 41, lower seal nipple 42 with And compressed spring 43;The adjusting screw 44 is screwed in vertical pivot upper end, and the upper seal nipple 41, lower seal nipple 42 are located at perpendicular In chamber 32, the compressed spring 43 is between upper seal nipple 41 and lower seal nipple 42, lower 42 lower end of seal nipple Abut fixing sleeve 51.O-ring seals are respectively set in two seal nipple side walls, for promoting and erecting the sealing between 32 inner wall of chamber Property.Rotation, which adjusts screw 44, can control position of the seal nipple 41 in perpendicular chamber 32, erect in chamber 32 in upper seal nipple 41 After being depressed, compressed spring 43 increases the elasticity of lower seal nipple 42, keeps the abutting of lower seal nipple 42 more firmly solid Surely 51, the i.e. downward abutting power of promotion moving valve plate 52 are covered, the leakproofness of moving valve plate 52 is promoted.
As shown in Fig. 6 Fig. 7 Fig. 8, the valve port switch area of the valve body 1 opens up annular groove, consolidates in the annular groove The quiet valve block 7 of fixed setting annular, the outlet of each tributary circuit are provided on the quiet valve block 7 of annular, and the upper surface of the quiet valve block 7 is For the quiet valve face.The contact surface of 52 the two of quiet valve block 7 and moving valve plate is all high-precision mirror ultrafinish, improves end face Leakproofness.Quiet 7 material of valve block: 0.05 surface mirror ultrafinish (mirror surface of 2Cr13 stainless steel quenching and tempering hardness HRc30-35 flatness 3000-5000 mesh).
If specifically, in the present embodiment 17 tributary circuits be divided into 4 paraffin accesses, 71,12 reagent accesses 72 and 1 is changed liquid access 73;
The quiet valve face of annular is divided into paraffin area and reagent area;4 outlets of paraffin access 71 are provided with paraffin area, and 12 reagents are logical The outlet on road 72 and 1 outlet for changing liquid access 73 are provided with reagent area.
12 reagent accesses 72 are separately connected 12 reagent chambers, and 4 paraffin accesses 71 are separately connected 4 paraffin chambers 81, change Liquid access 73 connects outside;Total access 1A connection working chamber 82, when working chamber 82 needs to clean, by working chamber 82 with change Liquid access 73 connects, and replaces working chamber liquid with outside liquid by changing liquid access 73.
To prevent various reagents and paraffin from leaking, overflow passage 1B, the quiet valve block of annular are opened up in valve body 1 Decanting zone is formed on valve body 1 among 7, the decanting zone height is lower than the quiet valve face of annular, the import of the overflow passage 1B It is provided on decanting zone;Radial overflow launder 74, the radial direction overflow are opened up on the valve port switch area of paraffin area two sides respectively Slot 74 connects decanting zone.Radial polyrrhea groove on quiet valve block 7 can effectively prevent leakage paraffin and flow into adjacent reagent access 72, make At the blocking of reagent access 72, the global reliability of valve is improved.
Switching valve of the invention is mounted in tissue processor, is used for working chamber 82 and each reagent chamber and paraffin chamber 81 connections, the reagent of each reagent chamber storage various concentration, when working chamber 82 needs reagent, crossing axle assemble rotation will be moved Valve block 52 turns to corresponding reagent access 72 and exports, and is connected to corresponding reagent chamber with working chamber 82 by crossing axle assemble, work Making chamber 82 keeps negative pressure that the reagent in reagent chamber is delivered to working chamber 82, when working chamber 82 needs paraffin, gap bridge group Moving valve plate 52 is turned to corresponding paraffin access 71 and exported by part rotation, by crossing axle assemble for corresponding paraffin chamber 81 and work Chamber 82 is connected to.
Switching valve of the invention, leakproofness is high, and when tightening adjusting screw 44, compressed spring 43 is compressed, and gives moving valve plate 52 apply an axial force, by being adjacent on quiet 7 end face of valve block tightly of moving valve plate 52.It ensure that valve block end face is relatively moving During can reliably seal.And poorly sealed feelings caused by the factors such as effective compensation is because expanding with heat and contract with cold, part's machining errors Condition occurs, and improves the sealing reliability of valve.
Taking the above-mentioned ideal embodiment according to the present invention as inspiration, through the above description, relevant staff is complete Various changes and amendments can be carried out without departing from the scope of the technological thought of the present invention' entirely.The technology of this invention Property range is not limited to the contents of the specification, it is necessary to which the technical scope thereof is determined according to the scope of the claim.

Claims (10)

1. a kind of tissue processor, characterized in that including body, reagent tank group, paraffin cylinder group, work are provided on the body Chamber and fluid path switching valve, the working chamber are connected between reagent tank group and paraffin cylinder group respectively through fluid path switching valve;
It is equipped with valve road in the fluid path switching valve and switches datum level, the valve road switching datum level is highly higher than reagent on body Cylinder group, paraffin cylinder group, the highest in working chamber work liquid level.
2. tissue processor according to claim 1, characterized in that the fluid path switching valve includes valve body and gap bridge Component;
Total access and multiple tributary circuits are opened up on the valve body, the valve body upper surface is equipped with the quiet valve face of annular, respectively The outlet of a tributary circuit is provided with respectively on the quiet valve face of annular, and the import of total access is provided at the quiet valve face center of annular Valve body on;
Described cross is equipped with gap bridge access in axle assemble, the axle assemble of crossing includes inlet end and an outlet end, the gap bridge access Import is provided with input end, and the gap bridge lane exit is provided with outlet end, outlet end and the total access of the gap bridge access Import rotary seal connection, the input end for crossing axle assemble form dynamic valve face, the dynamic valve face and valve body for crossing axle assemble The quiet valve face of annular be slidingly sealed cooperation;
Contact surface between the dynamic valve face and the quiet valve face of annular is that the valve road switches datum level.
3. tissue processor according to claim 2, characterized in that the axle assemble of crossing includes mandrel and bridge shaft, institute It states and is equipped with the first gap bridge channel in bridge shaft, be equipped with the second gap bridge channel, the bridge shaft outlet end and mandrel in the mandrel Input end is sealedly and fixedly connected, so that the first gap bridge channel is connected to the second gap bridge channel.
4. tissue processor according to claim 3, characterized in that the entrance of total access forms step installation Mouthful, the step installing port is equipped with T shape axle sleeve, and rolling bearing is provided on the T shape axle sleeve, and the mandrel lower end connection rolls Bearing and T shape axle sleeve.
5. tissue processor according to claim 4, characterized in that be provided with valve chest, the mistake on the valve body The shell that axle assemble is located at valve chest is intracavitary, and the upper end of the mandrel passes through valve chest, is provided between the mandrel and valve chest Angle thrust bearing;The mandrel upper end is provided with belt pulley, the percutaneous band connection motor of belt pulley.
6. tissue processor according to claim 3, characterized in that the bridge shaft includes horizontal axis and vertical pivot, the cross Horizontal chamber is opened up in axis, perpendicular chamber is opened up in the vertical pivot, and the perpendicular chamber is connected to horizontal chamber, and the horizontal chamber is connected to the second gap bridge channel;
The vertical pivot lower end is sleeved and fixed, and the fixing sleeve slides up and down seal-moving, the fixing sleeve in vertical pivot lower end Moving valve plate is fixedly installed in lower end, opens up valve opening on the moving valve plate, perforation, the moving valve plate lower end surface are opened up on the fixing sleeve The as described dynamic valve face, it is described erect it is intracavitary be provided with flexible adjustment mechanism so as to be fitted tightly over annular quiet for the dynamic valve face On valve face.
7. tissue processor according to claim 6, characterized in that the elastic adjusting mechanism include adjust screw, on Seal nipple, lower seal nipple and compressed spring;The adjusting screw is screwed in vertical pivot upper end, the upper seal nipple, under Seal nipple is intracavitary positioned at erecting, and the compressed spring is between upper seal nipple and lower seal nipple, the lower seal nipple Lower end abuts fixing sleeve.
8. tissue processor according to claim 2, characterized in that it is recessed that the valve port switch area of the valve body opens up annular Slot, the quiet valve block of the interior fixed setting annular of the annular groove, the outlet of each tributary circuit is provided on the quiet valve block of annular, described The upper surface of quiet valve block is the quiet valve face.
9. tissue processor according to claim 8, characterized in that
Each tributary circuit is divided into several paraffin accesses, several reagent accesses and one change liquid access;
The quiet valve face of annular is divided into paraffin area and reagent area;
Each paraffin lane exit is provided with paraffin area, and the outlet of each reagent access and the outlet for changing liquid access are provided with Reagent area.
10. tissue processor according to claim 8, characterized in that open up overflow passage, the ring in the valve body Decanting zone is formed on valve body among the quiet valve block of shape, the decanting zone height is lower than the quiet valve face of annular, the overflow passage Import is provided on decanting zone;
Radial overflow launder is opened up on the valve port switch area of paraffin area two sides respectively, the radial direction overflow launder connects decanting zone.
CN201910439241.9A 2019-05-24 2019-05-24 Tissue dehydrator Active CN110108533B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910439241.9A CN110108533B (en) 2019-05-24 2019-05-24 Tissue dehydrator

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910439241.9A CN110108533B (en) 2019-05-24 2019-05-24 Tissue dehydrator

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Publication Number Publication Date
CN110108533A true CN110108533A (en) 2019-08-09
CN110108533B CN110108533B (en) 2023-10-24

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