CN110101827A - A kind of Chinese materia medica preparation for treating hyperplasia of prostate - Google Patents
A kind of Chinese materia medica preparation for treating hyperplasia of prostate Download PDFInfo
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/906—Zingiberaceae (Ginger family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention belongs to technical field of traditional Chinese medicines, especially a kind of Chinese materia medica preparation for treating hyperplasia of prostate;The Chinese materia medica preparation is prepared from the following raw materials by weight: 8-12 parts of red ginseng, 12-17 parts of rhizoma atractylodis macrocephalae, 12-17 parts of Yun Ling, 8-12 parts of rhizoma zingiberis, 8-12 parts of fructus amomi, 6-10 parts of method summer, 12-17 parts of fructus lycii, 12-17 parts of HERBA EPIMEDII, Psoralen be stir-bake to yellowish 12-17 parts sub-, 12-17 parts of Semen Cuscutae stir-bake to yellowish, 6-10 parts of pilose antler stir-bake to yellowish, 7-12 parts of radix glycyrrhizae preparata, 8-12 parts of semen plantaginis stir-bake to yellowish, the preparation method comprises the following steps: weighing each raw material mixed grinding by above-mentioned parts by weight, medicinal powder is obtained;Light salt brine is added to medicinal powder to be uniformly mixed, obtains mixture;After mixture is decocted 20-25min, natural is added thereto, is further continued for decocting 25-30min, filtering sterilizes to get Chinese materia medica preparation.Chinese materia medica preparation prepared by the present invention has air making-up and spleen enlivening, clearing damp and promoting diuresis, yang-tonifying QI invigorating, recover Yang and smooth venation, middle benefit gas by cold and other effects, for causing the complication such as hyperplasia of prostate and impotence, cool, the weak essence of essence to have good therapeutic effect.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, more particularly, to a kind of Chinese materia medica preparation for treating hyperplasia of prostate.
Background technique
Hyperplasia of prostate (hyperplasia of prostate), commonly referred to as benign prostatic hyperplasis, are middle-aging males
One of common disease is fallen ill increasing with population in the world astogeny.The essence of hyperplasia of prostate is mainly shown as that prostate fills
Hemotoncus is swollen, body of gland connective tissue and proliferation of smooth muscle, forms multiple spherical tubercle, urethra;Clinical signs are urination
Difficulty, frequent micturition, urgent urination, enuresis nocturna increase, the urinary incontinence etc., further development may cause urinary hesitancy, vesical calculus, urinary tract infections,
Renal pelvis ureters ponding, renal failure etc., while with impotence, weak essence, infertility, weak essence, the essence complication such as cool.
Currently, the clinical treatment of hyperplasia of prostate is broadly divided into drug therapy, operative treatment, minimally-invasive treatment, drug
Treat use mainly with the antibiotic such as 5α-reductase inhibitor, alpha 1-receptor retarding agent, operative treatment most commonly passes through
Urethra prostatectomy, transurethral incision of prostate, open prostatectomy, minimally-invasive treatment have per urethra prostate
Electrovaporization, per urethra prostate Penile erectile function, per urethra plasma Enucleation of the prostate, laser therapy, microwave
Treatment.Drug therapy can cause biggish toxic side effect to human body;There are expensive, safeties for operative treatment and minimally-invasive treatment
Difference, the problem big to human injury.Therefore, lot of domestic and foreign medical worker grinds the Chinese medicine of hyperplasia of prostate
Study carefully, and achieves certain effect;But arbitrariness is also big for these Chinese medicines, and therapeutic effect is slower;Or to impotence, infertility,
Weak essence, the essence complications Treatments effect such as cool are poor.Such as application No. is the kind treatments of the patent disclosure of CN201610683845.4
The Chinese medicine composition of hyperplasia of prostate, including Chinese medicine composition one and Chinese medicine composition two, composition one is by following parts by weight
Bulk pharmaceutical chemicals composition: 5-15 parts of monkshood, 20-30 parts of cortex cinnamomi, 20-40 parts of Radix Astragali, 5-15 parts of red ginseng, 10-20 parts of cattail pollen, Shi Gepu
10-20 parts, 20-30 parts of Poria cocos, 15-25 parts of Semen Vaccariae (parched), 10-20 parts of chingma abutilon seed, 10-20 parts of dianthus superbus, Artemisia anomala 20-30
Part, 10-20 parts of radix achyranthis bidentatae, 10-18 parts of pangolin;Composition two is made of the bulk pharmaceutical chemicals of following parts by weight: pangolin 100-150
Part, 30-50 parts of amber, 40-60 parts of Morinda officinalis, 10-30 parts of agalloch eaglewood;All medicines share both rouse oneself kidney yang, functioning of bladder recovery,
And the turbid cleaning of dispersing blood stasis dissipating bind, the stasis of blood, water channel are then led to, water-wet is certainly sharp;The composition has a good curative effect to hyperplasia of prostate, but for
Impotence, infertility, weak essence, the essence complication weak curative effect such as cool.
Summary of the invention
The purpose of the present invention is to provide a kind of Chinese materia medica preparations for treating hyperplasia of prostate, for hyperplasia of prostate and sun
Impotence, infertility, weak essence, the essence complication such as cool have good curative effect;It is realized particular by following technical scheme:
A kind of Chinese materia medica preparation for treating hyperplasia of prostate, is made of raw material from the following weight: 8-12 parts of red ginseng, rhizoma atractylodis macrocephalae
12-17 parts, 12-17 parts of Yun Ling, 8-12 parts of rhizoma zingiberis, 8-12 parts of fructus amomi, 6-10 parts of method summer, 12-17 parts of fructus lycii, HERBA EPIMEDII 12-17
Part, Psoralen is stir-bake to yellowish 12-17 parts sub-, 12-17 parts of Semen Cuscutae stir-bake to yellowish, 6-10 parts of pilose antler stir-bake to yellowish, 7-12 parts of radix glycyrrhizae preparata, semen plantaginis stir-bake to yellowish
8-12 parts.
Preferably, the Chinese materia medica preparation of the treatment hyperplasia of prostate, is made of raw material from the following weight: red ginseng 10
Part, 15 parts of rhizoma atractylodis macrocephalae, 15 parts of Yun Ling, 10 parts of rhizoma zingiberis, 10 parts of fructus amomi, 8 parts of method summer, 15 parts of fructus lycii, 15 parts of HERBA EPIMEDII, Psoralen are fried
Yellow 15 parts, 15 parts of Semen Cuscutae stir-bake to yellowish, 8 parts of pilose antler stir-bake to yellowish, 9 parts of radix glycyrrhizae preparata, 10 parts of semen plantaginis stir-bake to yellowish.
Preferably, it is described treatment hyperplasia of prostate Chinese materia medica preparation the preparation method comprises the following steps: weighing each original by above-mentioned parts by weight
Expect mixed grinding, obtains medicinal powder;8-10 times of light salt brine is added to medicinal powder to be uniformly mixed, obtains mixture;Mixture is decocted into 50-
60min, filtering sterilize to get Chinese materia medica preparation.
Preferably, the granularity of the medicinal powder is 60-80 mesh.
Preferably, the mass concentration of the light salt brine is 8-10%.
Preferably, the mixture is decocted to after 25-30min, and natural is added into mixture.Mixture is decocted
After boiling 25-30min, the part effective component in raw material is also dissolved into light salt brine, continuation decoct backward, this part effectively at
Branch leads to its loss due to heated generation oxidation or decomposition, and then influences its drug effect;Natural is added to it
This chemical reaction occurs for the middle traditional Chinese medicine ingredients that can inhibit in light salt brine, it is made to keep good activity.
Preferably, the additive amount of the natural is the 3-5% of mixture quality.
Preferably, the natural is one of vitamin E, carrotene or a variety of.
Compared with prior art, the raw material that the present invention uses, effect are as follows with mechanism:
The present invention, which selects the 11 taste medicinal materials such as red ginseng, to be treated for the interpretation of the cause, onset and process of an illness of prostatic hyperplasia, sorting composition component
's.Lesion mechanism of the prostatic hyperplasia in Chinese medicine can be divided into: (1) exopathogen is invaded: exopathogen enters lung, and disturbance in ascending and descending leads to water transfer
The duty mistake department in road;Or lung heat pents up, and moves down bladder, disturbance in qi transformation etc..(2) diet internal injury: diet is uncomfortable, and delicious food processs Bo, breeds
It is damp and hot, bladder of betting;Or diet raw food, impairing the spleen and stomach, temper lose, middle gas is impaired, and clean air is sunk, and takes the photograph about powerless.(3) seven feelings
Become estranged: inernal injuries caused by seven emotions, gas agent are become estranged, and catharsis is too late, and channels and collaterals are unsmooth, influence spleen, stomach, kidney, three burnt, bladder mechanisms of qi and gasification function
Can, so that water channel is obstructed, causes this disease.(4) labor is intended to excessively: overstrain impairing the spleen, fleshliness are impairment of the kidney, and spleen kidney two loses, and are gasified too late, and bladder is logical
Benefit is obstructed, and can be caused a disease.(5) lose the turbid silt of essence: lust is excessive, or bears and do not let out, loses smart silt essential resistance of turbid, and functioning of bladder is unfavorable;Or urine
Road is obstructed, drainage difficulty, can very cause renal shutdown.The HERBA EPIMEDII that the present invention uses has the effect of tonifying kidney and strengthening yang, strong muscles and bones;Psoralen
Son have tonifying kidney and strengthening yang, astringent sperm contracting urine, it is warming spleen and stopping diarrha the effects of;Semen Cuscutae has the function of yang-tonifying QI invigorating, astringent sperm contracting urine, improving eyesight antidiarrheal
Effect;Pilose antler plays the role of kidney tonifying void, benefiting essence-blood, strengthening the bones and muscles, strengthen immunity;Four share for labor be intended to excessively, lose the turbid silt of essence
The hyperplasia of prostate of hair is caused to have a good effect.Fructus amomi has the effect of dampness elimination appetizing, warming spleen and stopping diarrha, qi-regulating;There is eliminating dampness in the method summer
The effect of resolving sputum;The effect of Yun Lingyou clearing damp and promoting diuresis, invigorating the spleen, calming heart;Rhizoma atractylodis macrocephalae has air making-up and spleen enlivening, eliminate dampness and have diuretic effect, hidroschesis, adjusting
The effects of immunocompetence, antitumor, protection liver are said;Semen plantaginis have effects that Li Shui, heat-clearing, eliminating the phlegm;Five share for
Exopathogen invasion, diet internal injury cause the hyperplasia of prostate of hair to have a good effect.Red ginseng, which has, to reinforce vital energy, promotes the production of body fluid to quench thirst, pacifying
The effect of refreshing intelligence development, qi-restoratives righting;Rhizoma zingiberis has middle benefit gas by cold, recover Yang and smooth venation, anti-inflammatory, anticoagulation and other effects;Fructus lycii has nourishing the liver, grows
The effect of kidney, moistening lung;Three, which shares, to be hurt seven feelings and the hyperplasia of prostate of hair is caused to have a good effect.Radix glycyrrhizae preparata has in
The effect of emergency, moistening lung, removing toxic substances, coordinating the drug actions of a prescription, guides drugs to illness station all medicines to make.
In summary it is found that Chinese materia medica preparation provided by the invention has air making-up and spleen enlivening, clearing damp and promoting diuresis, yang-tonifying QI invigorating, Hui Yang
Promote blood circulation, middle benefit gas is by cold and other effects, for causing the interpretation of the cause, onset and process of an illness of hyperplasia of prostate to have good curative effect, while to impotence, cool, the weak essence of essence
Etc. complication have good therapeutic effect.
Specific embodiment
It is limited below with reference to specific embodiment technical solution of the present invention is further, but claimed
Range is not only limited to made description.
Embodiment 1
Formula: red ginseng 8g, rhizoma atractylodis macrocephalae 12g, Yun Ling 12g, rhizoma zingiberis 8g, fructus amomi 8g, method summer 6g, fructus lycii 12g, HERBA EPIMEDII 12g,
The sub- stir-bake to yellowish 12g of Psoralen, Semen Cuscutae stir-bake to yellowish 12g, pilose antler stir-bake to yellowish 6g, radix glycyrrhizae preparata 7g, semen plantaginis stir-bake to yellowish 8g.
Preparation method: each raw material mixed grinding is weighed to 80 mesh by above-mentioned parts by weight, obtains medicinal powder;It is light to 8 times of medicinal powder addition
Salt water is uniformly mixed, and obtains mixture;After mixture is decocted 25min, vitamin E is added thereto, is further continued for decocting 25min,
Filtering sterilizes to get Chinese materia medica preparation.Wherein, the mass concentration of light salt brine is 8%, and the additive amount of vitamin E is mixture quality
5%.
Application method: two times a day, each 4-5g avoids pungent, raw and cold, tobacco and wine during medication.
2 oral preparation of embodiment
Formula: red ginseng 10g, rhizoma atractylodis macrocephalae 15g, Yun Ling 15g, rhizoma zingiberis 10g, fructus amomi 10g, method summer 8g, fructus lycii 15g, HERBA EPIMEDII
The sub- stir-bake to yellowish 15g of 15g, Psoralen, Semen Cuscutae stir-bake to yellowish 15g, pilose antler stir-bake to yellowish 8g, radix glycyrrhizae preparata 9g, semen plantaginis stir-bake to yellowish 10g.
Preparation method: each raw material mixed grinding is weighed to 70 mesh by above-mentioned parts by weight, obtains medicinal powder;It is light to 8 times of medicinal powder addition
Salt water is uniformly mixed, and obtains mixture;After mixture is decocted 28min, carrotene is added thereto, is further continued for decocting 28min,
Filtering sterilizes to get Chinese materia medica preparation.Wherein, the mass concentration of light salt brine is 8.5%, and the additive amount of natural is mixed
Close the 4% of material quality.
Application method: with embodiment 1.
Embodiment 3
Formula: red ginseng 12g, rhizoma atractylodis macrocephalae 17g, Yun Ling 17g, rhizoma zingiberis 12g, fructus amomi 12g, method summer 10g, fructus lycii 17g, HERBA EPIMEDII
The sub- stir-bake to yellowish 17g of 17g, Psoralen, Semen Cuscutae stir-bake to yellowish 17g, pilose antler stir-bake to yellowish 10g, radix glycyrrhizae preparata 12g, semen plantaginis stir-bake to yellowish 12g.
Preparation method: each raw material mixed grinding is weighed to 80 mesh by above-mentioned parts by weight, obtains medicinal powder;It is light to 10 times of medicinal powder addition
Salt water is uniformly mixed, and obtains mixture;After mixture is decocted 30min, natural is added thereto, is further continued for decocting
30min, filtering sterilize to get Chinese materia medica preparation.Wherein, the mass concentration of light salt brine is 8-10%;Natural is given birth to by dimension
Plain E, carrotene are mixed in the ratio of 1:1, and additive amount is the 5% of mixture quality.
Application method: with embodiment 1.
Experimental example typical case
Case 1
It is remaining so-and-so, male, Han nationality 42 years old, lives ten groups of the village He Zhong, the Guizhou township Pan Zhoushi Pu Gu, phone: 15186301982,
Checked to be prostatitis hyperplasia through hospital in 2015, goes to check that sperm refers to value, it is low defective ejaculation, survival rate occur;And body at that time
There is impotence, early pond, cold limbs, anorexia and loose stool problem in body;Take Chinese materia medica preparation 10 days prepared by the embodiment of the present invention 3
Afterwards, impotence, cold limbs, anorexia and loose stool symptom have got well many, and continue to take three courses for the treatment of (10 days as a treatment course), fully recover from an illness
More, it checks that all indexs are normal through hospital, was not yet recurred so far from 2015.
Case 2
Ancestral so-and-so, male, Han nationality 38 years old, lives five groups of cover river village, chicken house level ground township, the city Lupanshui City Pan Zhou, Guizhou Province, electricity
Words: 18984434301,2014 through hospital check be prostatitis hyperplasia, go check sperm refer to value, occur sperm it is weak, at
Motility rate is low, and it is swollen pain occur;It had a surplus at hospitalize 2 months, never effect;2 institute of the embodiment of the present invention is taken after being introduced
After one course for the treatment of of Chinese materia medica preparation (10 days as a treatment course) of preparation, pain is swollen to be mitigated, and continues to take two courses for the treatment of, is fully recovered, is gone
Hospital check routine index of semen is normal, the scorching hyperplasia of hyperplasia of prostate also without;His lover is just pregnant after curing half a year, to then
Half his lover of second year be pregnant again, the two male's healths given birth to;It was had not relapsed so far from 2014.
Case 3
Yang, male, Han nationality 35 years old, live 17 groups of the village Cha Gou, the city Lupanshui City Pan Zhou, Guizhou Province, phone:
18257572208,2015 through hospital check be hyperplasia of prostate, go check sperm refer to value, occur weak sperm, defective ejaculation, at
Motility rate is low, distending pain, frequent micturition occurs;Taking one course for the treatment of of Chinese materia medica preparation prepared by the embodiment of the present invention 1, (10 days are a treatment
Journey) after, distending pain mitigates, frequent micturition reduces number, and continues to take two courses for the treatment of, fully recovers, goes all indexs of hospital normal;From 2015
Year has not relapsed so far.
It is important to point out that, above embodiments and experimental example are only limitted to do further technical solution of the present invention herein
Elaboration and understanding, should not be understood as it is further to technical solution of the present invention limited, what those skilled in the art made
The innovation and creation of non-protruding essential characteristics and marked improvement still fall within protection category of the invention.
Claims (8)
1. a kind of Chinese materia medica preparation for treating hyperplasia of prostate, is made of raw material from the following weight: 8-12 parts of red ginseng, rhizoma atractylodis macrocephalae
12-17 parts, 12-17 parts of Yun Ling, 8-12 parts of rhizoma zingiberis, 8-12 parts of fructus amomi, 6-10 parts of method summer, 12-17 parts of fructus lycii, HERBA EPIMEDII 12-17
Part, Psoralen is stir-bake to yellowish 12-17 parts sub-, 12-17 parts of Semen Cuscutae stir-bake to yellowish, 6-10 parts of pilose antler stir-bake to yellowish, 7-12 parts of radix glycyrrhizae preparata, semen plantaginis stir-bake to yellowish
8-12 parts.
2. the Chinese materia medica preparation for the treatment of hyperplasia of prostate as described in claim 1, which is characterized in that by the raw material of following parts by weight
It is made: 10 parts of red ginseng, 15 parts of rhizoma atractylodis macrocephalae, 15 parts of Yun Ling, 10 parts of rhizoma zingiberis, 10 parts of fructus amomi, 8 parts of method summer, 15 parts of fructus lycii, HERBA EPIMEDII 15
Part, 15 parts of the sub- stir-bake to yellowish of Psoralen, 15 parts of Semen Cuscutae stir-bake to yellowish, 8 parts of pilose antler stir-bake to yellowish, 9 parts of radix glycyrrhizae preparata, 10 parts of semen plantaginis stir-bake to yellowish.
3. the preparation method of the Chinese materia medica preparation for the treatment of hyperplasia of prostate as claimed in claim 1 or 2, which is characterized in that including
Following procedure: each raw material mixed grinding is weighed by above-mentioned parts by weight, obtains medicinal powder;It is equal that 8-10 times of light salt brine mixing is added to medicinal powder
It is even, obtain mixture;Mixture is decocted into 50-60min, is filtered, is sterilized to get Chinese materia medica preparation.
4. the preparation method that the Chinese materia medica preparation of hyperplasia of prostate is treated in treatment as claimed in claim 3, which is characterized in that the medicine
The granularity of powder is 60-80 mesh.
5. the preparation method that the Chinese materia medica preparation of hyperplasia of prostate is treated in treatment as claimed in claim 3, which is characterized in that described light
The mass concentration of salt water is 8-10%.
6. the preparation method that the Chinese materia medica preparation of hyperplasia of prostate is treated in treatment as claimed in claim 3, which is characterized in that described mixed
It closes material to decoct to after 25-30min, natural is added into mixture.
7. the preparation method that the Chinese materia medica preparation of hyperplasia of prostate is treated in treatment as claimed in claim 6, which is characterized in that the day
The additive amount of right antioxidant is the 3-5% of mixture quality.
8. the preparation method that the Chinese materia medica preparation of hyperplasia of prostate is treated in treatment as claimed in claim 6, which is characterized in that the day
Right antioxidant is one of vitamin E, carrotene or a variety of.
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CN1720934A (en) * | 2004-07-16 | 2006-01-18 | 王保安 | Medicine for treating prostate hyperplasia and method of preparing the same |
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CN102114194A (en) * | 2011-03-02 | 2011-07-06 | 徐海彬 | Medicament for treating prostatic disease |
CN104524109A (en) * | 2014-12-30 | 2015-04-22 | 周连才 | Medicine for treating kidney-yang deficiency involution form benign prostatic hyperplasia and preparing method |
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Application publication date: 20190809 |