CN110101768A - A kind of black plaster formula that treating osteoarthropathy and its preparation process - Google Patents

A kind of black plaster formula that treating osteoarthropathy and its preparation process Download PDF

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CN110101768A
CN110101768A CN201910520567.4A CN201910520567A CN110101768A CN 110101768 A CN110101768 A CN 110101768A CN 201910520567 A CN201910520567 A CN 201910520567A CN 110101768 A CN110101768 A CN 110101768A
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preparation process
sesame oil
formula
fry
black
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郭珈宜
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Medical Informatics (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention provides a kind of black plaster formula for treating osteoarthropathy and its preparation process, the formula is made of according to parts by weight bulk pharmaceutical chemicals Radix Angelicae Sinensis 55-65g, Radix Rehmanniae 110-130g, rheum officinale 110-130g, Radix Angelicae Pubescentis 55-65g, olibanum 15-25g, myrrh 20-25g and true sesame oil 4800-5200 milliliters.The present invention provides a kind of black plaster formula for treating osteoarthropathy and its preparation processes, have the effect of promoting blood circulation and stopping pain, dispelling wind and eliminating dampness, antalgic, can effectively treat soft tissue injury, the injury of tendon and muscle, the diseases significant effect such as strain property pain.

Description

A kind of black plaster formula that treating osteoarthropathy and its preparation process
Technical field
The present invention relates to field of traditional Chinese medicine formula, in particular to a kind of black plaster formula for treating osteoarthropathy and its preparation works Skill.
Background technique
Osteoarthropathy is most common one of the illness of orthopedics and traumatology, and " numbness disease " scope is belonged in traditional Chinese medicine, is occurred former Because related by wound, labour, movement with human body, strength torsion, drawing compressing etc. cause the tissue except the following bone of skin Acute injury including the tissues such as muscle, ligament, fascia, tendon, synovial membrane, joint capsule and peripheral nerve, blood vessel, but there is no bone Folding, phenomenon of dislocating, are mainly shown as pain, the swelling of Bones and joints, some also will cause dysfunction.Western medical treatment is more Take non-steroidal anti-inflammatory drug, such as brufen, diclofenac for a long time, not only uncertain therapeutic efficacy is cut, and can also be generated a variety of bad Reaction.Plaster is affixed on affected part stimulation nerve endings and expands blood vessel by reflection, promotes local blood circulation, generates neural specific Property, strength is resisted with Adjusting Mechanism enhancing tissue, reaches calm, antiinflammation.Moreover, after drug break-through skin and mucous membrane, warp It crosses blood vessel or lymphatic vessel enters body circulation and can produce general action.
Summary of the invention
To solve the problems mentioned in the above background technology, the purpose of the present invention is to provide a kind of osteoarthropathy for the treatment of Black plaster formula and its preparation process, the black plaster formula have the effect of promoting blood circulation and stopping pain, dispelling wind and eliminating dampness, antalgic, can have Effect treatment soft tissue injury, the injury of tendon and muscle, the diseases significant effect such as strain property pain.
In order to solve the above technical problems, technical solution provided by the invention are as follows:
A kind of black plaster formula that treating osteoarthropathy and its preparation process, the formula is according to parts by weight by bulk pharmaceutical chemicals Radix Angelicae Sinensis 55-65g, Radix Rehmanniae 110-130g, rheum officinale 110-130g, Radix Angelicae Pubescentis 55-65g, olibanum 15-25g, myrrh 20-25g and true sesame Oily 4800-5200 milliliters of composition;
The preparation process the following steps are included:
1) raw material is weighed according to weight, is ground into yellow powder for Six-element herbal medicine is fine, then mix with red Cinnabar Get up spare;
2) fry red: the mixture that step 1) is obtained is put into clean iron pan or copper pot, is fried with slow fire water in mixture Gas consumption is most, loose to spend, spare;
3) it boils lubricate: measuring true sesame oil, true sesame oil intense fire is boiled into magic flower, then change mild fire, temperature reaches 300 DEG C When, it is calculated by every 500g true sesame oil red lead 195g, the stir-fry pellet that step 2) obtains slowly is put into boiling oil, step 1) is obtained To medicinal powder pour into pot, keep stirring, 9-10 hour heated on firewood, is boiled into black medicine slurry, remove slag and filter only, as cream Oil;
4) lubricate that step 3) obtains is poured into cold water with thread, constantly strong stirring, condensation to be cooled is taken out, rubbed with the hands repeatedly It rubs, squeezes the water out and agglomerate is made, and agglomerate is set in cold water and is impregnated, it is spare;
5) medicine block that step 4 obtains is heated as black ointment again, is applied on coarse cloth, that is, completes soft group for the treatment of Knit the preparation of the promoting blood circulation bone-setting pain stopping paste formulation of strain property pain.
As an improvement, the stir-fry pellet in the step 2) needs using very hot oven and to make to constantly stir fry with shovel.
The beneficial effects of the present invention are:
A kind of black plaster formula for treating osteoarthropathy provided by the invention, can treat damage, the injury of tendon and muscle, labor of Bones and joints The damage property diseases such as pain, by acupuncture point meridian play drug promoting blood circulation, antalgic, dispelling wind and eliminating dampness effect, Adjusting Mechanism increases Strong tissue resists strength, reaches calm, antiinflammation.Have the function of percutaneous absorbtion, and is avoided that the " first to cross work of liver With ", it avoids drug in the destruction of gastrointestinal tract, reduces the variation of blood concentration peak valley, overcome side effects of pharmaceutical drugs, make up the efficacy of a drug for oral administration Deficiency, act on it is more lasting than ointment.
Preparation process of the invention is simple, and production cost is low, and mixed-powder mutual compatibility promoting blood circulation, connects swelling and pain relieving Bone continues muscle, dispelling wind and eliminating dampness.These powder enter drug effect after human body and play significant effect, be avoided that in high temperature decoction process effectively at Shunt and lose, and make excipient using red, oily cook paste, can anti-corrosion, prevent dry, protection sore face, keep lasting medicine, promote drug and warp It crosses epidermis and generates deep and general action.Therefore the black plaster prescription drug bioavilability being prepared is high, drug effect is more aobvious It writes, is suitable for popularization and application.
Specific embodiment
Illustrate the present invention with specific embodiment below, is not limitation of the present invention.
Embodiment one
A kind of black plaster formula that treating osteoarthropathy and its preparation process, which is characterized in that the formula is according to weight Part is measured by bulk pharmaceutical chemicals Radix Angelicae Sinensis 60g, Radix Rehmanniae 120g, rheum officinale 120g, Radix Angelicae Pubescentis 60g, 5000 milli of olibanum 20g, myrrh 20g and true sesame oil Rise composition;
The preparation process the following steps are included:
1) raw material is weighed according to weight, is ground into yellow powder for Six-element herbal medicine is fine, then mix with red Cinnabar Get up spare;
2) fry red: the mixture that step 1) is obtained is put into clean iron pan or copper pot, is fried with slow fire water in mixture Gas consumption is most, loose to spend, spare;
3) it boils lubricate: measuring true sesame oil, true sesame oil intense fire is boiled into magic flower, then change mild fire, temperature reaches 300 DEG C When, it is used by the true sesame oil of every 500g and fries pellet 195g calculating, the stir-fry pellet that step 2) obtains slowly is put into boiling oil, step 1) is obtained To medicinal powder pour into pot, keep stirring, 10 hours heated on firewood, are boiled into black medicine slurry, removing slag, it is net to filter, as cream Oil;
4) lubricate that step 3) obtains is poured into cold water with thread, constantly strong stirring, condensation to be cooled is taken out, rubbed with the hands repeatedly It rubs, squeezes the water out and agglomerate is made, and agglomerate is set in cold water and is impregnated, it is spare;
5) medicine block that step 4 obtains is heated as black ointment again, is applied on coarse cloth, that is, completes soft group for the treatment of Knit the preparation of the promoting blood circulation bone-setting pain stopping paste formulation of strain property pain.
Stir-fry pellet in the step 2) needs using very hot oven and to make to constantly stir fry with shovel.
Embodiment two
A kind of black plaster formula that treating osteoarthropathy and its preparation process, the formula is according to parts by weight by bulk pharmaceutical chemicals Radix Angelicae Sinensis 55-65g, Radix Rehmanniae 110g, rheum officinale 125g, Radix Angelicae Pubescentis 55g, olibanum 25g, myrrh 20g and 5200 milliliters of true sesame oil compositions;
The preparation process the following steps are included:
1) raw material is weighed according to weight, is ground into yellow powder for Six-element herbal medicine is fine, then mix with red Cinnabar Get up spare;
2) fry red: the mixture that step 1) is obtained is put into clean iron pan or copper pot, is fried with slow fire water in mixture Gas consumption is most, loose to spend, spare;
3) it boils lubricate: measuring true sesame oil, true sesame oil intense fire is boiled into magic flower, then change mild fire, temperature reaches 300 DEG C When, it is used by the true sesame oil of every 500g and fries pellet 195g calculating, the stir-fry pellet that step 2) obtains slowly is put into boiling oil, step 1) is obtained To medicinal powder pour into pot, keep stirring, 9.5 hours heated on firewood, are boiled into black medicine slurry, removing slag, it is net to filter, as cream Oil;
4) lubricate that step 3) obtains is poured into cold water with thread, constantly strong stirring, condensation to be cooled is taken out, rubbed with the hands repeatedly It rubs, squeezes the water out and agglomerate is made, and agglomerate is set in cold water and is impregnated, it is spare;
5) medicine block that step 4 obtains is heated as black ointment again, is applied on coarse cloth, that is, completes soft group for the treatment of Knit the preparation of the promoting blood circulation bone-setting pain stopping paste formulation of strain property pain.
Stir-fry pellet in the step 2) needs using very hot oven and to make to constantly stir fry with shovel.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (2)

1. a kind of black plaster formula for treating osteoarthropathy and its preparation process, which is characterized in that the formula is according to weight Part is by bulk pharmaceutical chemicals Radix Angelicae Sinensis 55-65g, Radix Rehmanniae 110-130g, rheum officinale 110-130g, Radix Angelicae Pubescentis 55-65g, olibanum 15-25g, myrrh 20- 25g and true sesame oil 4800-5200 milliliters of compositions;
The preparation process the following steps are included:
1) raw material is weighed according to weight, is ground into yellow powder for Six-element herbal medicine is fine, then mix with red Cinnabar It is spare;
2) fry red: the mixture that step 1) is obtained is put into clean iron pan or copper pot, is fried with slow fire aqueous vapor in mixture and is consumed To the greatest extent, loose to spend, it is spare;
3) it boils lubricate: measuring true sesame oil, true sesame oil intense fire is boiled into magic flower, then change mild fire, when temperature reaches 300 DEG C, press Every true sesame oil of 500g is calculated with pellet 195g is fried, and the stir-fry pellet that step 2) obtains slowly is put into boiling oil, step 1) is obtained Medicinal powder pours into pot, keeps stirring, and 9-10 hour is heated on firewood, is boiled into black medicine slurry, and removing slag, it is net to filter, as lubricate;
4) lubricate that step 3) obtains is poured into cold water with thread, constantly strong stirring, condensation to be cooled is taken out, is crumpled repeatedly, It squeezes the water out and agglomerate is made, and agglomerate is set in cold water and is impregnated, it is spare;
5) medicine block that step 4 obtains is heated as black ointment again, is applied on coarse cloth, that is, completes treatment soft tissue labor The preparation of the promoting blood circulation bone-setting pain stopping paste formulation of damage property pain.
2. a kind of black plaster formula for treating osteoarthropathy according to claim 1 and its preparation process, which is characterized in that Stir-fry pellet in the step 2) needs using very hot oven and to make to constantly stir fry with shovel.
CN201910520567.4A 2019-06-17 2019-06-17 A kind of black plaster formula that treating osteoarthropathy and its preparation process Withdrawn CN110101768A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101053609A (en) * 2006-04-10 2007-10-17 张华锋 Black plaster for treating hyperosteogeny and its preparing method
CN103405487A (en) * 2013-08-12 2013-11-27 南京弘典医药科技有限公司 Chinese medicine compound effective part with effect of treating arthritis
CN109010552A (en) * 2018-10-12 2018-12-18 中国中医科学院广安门医院 A kind of Chinese medicine composition and its preparation method and application
CN109453246A (en) * 2019-01-18 2019-03-12 周新华 A kind of black plaster composition

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101053609A (en) * 2006-04-10 2007-10-17 张华锋 Black plaster for treating hyperosteogeny and its preparing method
CN103405487A (en) * 2013-08-12 2013-11-27 南京弘典医药科技有限公司 Chinese medicine compound effective part with effect of treating arthritis
CN109010552A (en) * 2018-10-12 2018-12-18 中国中医科学院广安门医院 A kind of Chinese medicine composition and its preparation method and application
CN109453246A (en) * 2019-01-18 2019-03-12 周新华 A kind of black plaster composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
刘兰芝 等: "自制治伤药膏治疗胫骨结节骨骺炎48例", 《中国中医药现代远程教育》 *

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Application publication date: 20190809

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