CN110074994A - Microemulsified systems skin care item production technology - Google Patents

Microemulsified systems skin care item production technology Download PDF

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Publication number
CN110074994A
CN110074994A CN201910404335.2A CN201910404335A CN110074994A CN 110074994 A CN110074994 A CN 110074994A CN 201910404335 A CN201910404335 A CN 201910404335A CN 110074994 A CN110074994 A CN 110074994A
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CN
China
Prior art keywords
solution
skin care
care item
total
percent
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Pending
Application number
CN201910404335.2A
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Chinese (zh)
Inventor
谢坤
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Dongshengyuan Research Institute Guangzhou Co Ltd
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Dongshengyuan Research Institute Guangzhou Co Ltd
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Priority to CN201910404335.2A priority Critical patent/CN110074994A/en
Publication of CN110074994A publication Critical patent/CN110074994A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/06Emulsions
    • A61K8/068Microemulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • A61K8/553Phospholipids, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Abstract

The invention discloses microemulsified systems skin care item production technologies, comprising the following steps: S1: preparing solution A, solution B, solution C, solution D, solution E, solution F, solution G and Solution H respectively;S2: solution A, solution B, solution C, solution D, solution E, solution F, solution G and Solution H are poured into pot and are stirred and heated to 78~85 DEG C;S3: taking out after step S2 dissolution completely and pours into vacuum emulsification pot the inside is emulsified;S4: taking out after the completion of step S3 emulsification can be prepared by skin care item.The present invention, operation through the above steps improve skin care item active ingredient draws rate;Can in water phase solubilized water composition in solubilized oil components or oily phase;Promote the effect of formulation stability.

Description

Microemulsified systems skin care item production technology
Technical field
The present invention relates to skin care item production technical fields, specially microemulsified systems skin care item production technology.
Background technique
Shield, protection;Skin, skin;Product, product.Skin care item protect the skin-protection product of skin.As society passes through Being constantly progressive for Ji is abundant with material life, skin care item, is no longer there was only the thing risen of the rich just in the past.Nowadays it protects Skin product have come into ordinary citizen house as the popular vehicles.It plays the role of great to the spirit of people, image enhancing.But conventional skin care product The utilization rate of active constituent is at high cost 2% or so, and effect is general.
Summary of the invention
The purpose of the present invention is to provide microemulsified systems skin care item production technologies, improve skin care item active ingredient draws Rate;Can in water phase solubilized water composition in solubilized oil components or oily phase;The advantages of promoting formulation stability, solves routine The utilization rate of skin care item active constituent is at high cost 2% or so, and the problem that effect is general.
To achieve the above object, the invention provides the following technical scheme: microemulsified systems skin care item, which is characterized in that packet Include solution A, solution B, solution C, solution D, solution E, solution F, solution G and Solution H.
The solution A includes water 1, hydrolecithin, lecithin, water 2 and 1,2- pentanediol.
The solution B includes water and Sodium Hyaluronate.
The solution C includes water and acrylic acid esters co-polymer.
The solution D includes arginine.
The solution E includes ethylenediamine tetra-acetic acid.
The solution F include water, glycerol, Wild soybean, egg from, superoxide dismutase alcohol, dextran sulfate sodium, benzene oxygen second Alcohol, Sensiva SC50, sodium benzoate and potassium sorbate.
The solution G includes butanediol, 1,2- pentanediol, hydroxy phenylpropionyl amine benzoic acid and ascorbyl palmitate.
The Solution H includes pungent glycol and 1,2- hexylene glycol.
Preferably, the water 1 in the solution A accounts for the 87.78% of each solution percent of total, hydrogenates ovum in the solution A Phosphatide, lecithin and water 2 account for the 0.6% of each solution percent of total altogether, and it is total to account for each solution for 1,2- pentanediol in the solution A The 3% of percentage.
Preferably, the water in the solution B accounts for the 4% of each solution percent of total, the Sodium Hyaluronate in the solution B Account for the 0.04% of each solution percent of total.
Preferably, the water in the solution C accounts for the 2% of each solution percent of total, the esters of acrylic acid in the solution C Copolymer accounts for the 1% of each solution percent of total.
Preferably, the arginine in the solution D accounts for the 0.15% of each solution percent of total.
Preferably, the ethylenediamine tetra-acetic acid in the solution E accounts for the 0.03% of each solution percent of total.
Preferably, oneself, superoxide dismutase alcohol, dextran sulfate of the water in the solution F, glycerol, Wild soybean, egg Sodium, Phenoxyethanol, Sensiva SC50, sodium benzoate and potassium sorbate account for the 0.5% of each solution percent of total altogether.
Preferably, the butanediol in the solution G, 1,2- pentanediol, hydroxy phenylpropionyl amine benzoic acid and ascorbic acid palm fibre Glycerin monostearate accounts for the 0.5% of each solution percent of total altogether
Preferably, the pungent glycol and 1 in the Solution H, 2- hexylene glycol account for the 0.4% of each solution percent of total altogether.
Preferably, the production technology of the microemulsified systems skin care item, comprising the following steps:
S1: solution A, solution B, solution C, solution D, solution E, solution F, solution G and Solution H are prepared respectively;
S2: solution A, solution B, solution C, solution D, solution E, solution F, solution G and Solution H are poured into pot and stirs and adds Heat is to 78~85 DEG C;
S3: taking out after step S2 dissolution completely and pours into vacuum emulsification pot the inside is emulsified;
S4: taking out after the completion of step S3 emulsification can be prepared by skin care item.
Compared with prior art, beneficial effects of the present invention are as follows:
The present invention improves skin care item active ingredient draws rate;Can in water phase Solubilization of Water in solubilized oil components or oily phase Property ingredient;Promote the effect of formulation stability.
Detailed description of the invention
Fig. 1 is the flow chart of step of the present invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Referring to Fig. 1, the present invention provides a kind of technical solution: microemulsified systems skin care item, including it is solution A, solution B, molten Liquid C, solution D, solution E, solution F, solution G and Solution H, the water 1 in solution A account for the 87.78% of each solution percent of total, institute Hydrolecithin in solution A, lecithin and water 2 account for each solution percent of total altogether 0.6% is stated, 1,2- penta in the solution A Glycol accounts for the 3% of each solution percent of total, and the water in solution B accounts for the 4% of each solution percent of total, in the solution B Sodium Hyaluronate accounts for the 0.04% of each solution percent of total, and the water in solution C accounts for the 2% of each solution percent of total, described Acrylic acid esters co-polymer in solution C accounts for the 1% of each solution percent of total, and it is total that the arginine in solution D accounts for each solution The 0.15% of percentage, the ethylenediamine tetra-acetic acid in solution E account for the 0.03% of each solution percent of total, water in solution F, sweet Oil, Wild soybean, egg from, superoxide dismutase alcohol, dextran sulfate sodium, Phenoxyethanol, Sensiva SC50, sodium benzoate and Potassium sorbate accounts for the 0.5% of each solution percent of total altogether, butanediol, 1,2- pentanediol, hydroxy phenylpropionyl amine benzene in solution G Formic acid and ascorbyl palmitate account for the 0.5% of each solution percent of total, the pungent glycol and 1 in Solution H, 2- hexylene glycol altogether The 0.4% of each solution percent of total is accounted for altogether.
The solution A includes water 1, hydrolecithin, lecithin (lecithin is lipophilic nonionic surfactant), water 2 and 1,2- pentanediol (polyalcohol that carbon atom is 2-6), hydrolecithin, which has, to be removed in desaccharification, reduced sugar or polyglycereol at least Hydrophilic non-ionic surfactant of the residue of the hydrogen atom of one hydroxyl as hydrophilic group.
The solution B includes water and Sodium Hyaluronate.
The solution C includes water and acrylic acid esters co-polymer, and acrylic acid esters co-polymer has polyoxyethylene chain conduct The hydrophilic radical of hydrophilic group.
The solution D includes arginine.
The solution E includes ethylenediamine tetra-acetic acid.
The solution F includes water, glycerol, Wild soybean (Wild soybean is oil soluble active ingredients), egg from, superoxide dismutase Alcohol (superoxide dismutase alcohol is water-soluble active ingredient), dextran sulfate sodium, Phenoxyethanol, Sensiva SC50, benzene first Sour sodium and potassium sorbate.
The solution G includes butanediol (polyalcohol that carbon atom is 2-6), (carbon atom is the polynary of 2-6 to 1,2- pentanediol Alcohol), hydroxy phenylpropionyl amine benzoic acid and ascorbyl palmitate.
Hydrophilic non-ionic surfactant can be used a kind or more, and 0.05%-8% matter is preferably comprised in microemulsion Amount, further preferably 0.1%-7% mass are allowed to stablize in wider temperature, while obtaining good use feeling;It is hydrophilic Property non-surface-active agent, HLB is preferably greater than 8, more preferably 9 or more.Here, HLB indicates whole molecules in surfactant The molecular weight of the hydroxylic moiety occupied in amount.
The Solution H includes pungent glycol and 1,2- hexylene glycol.
The production technology of microemulsified systems skin care item, comprising the following steps:
S1: solution A, solution B, solution C, solution D, solution E, solution F, solution G and Solution H are prepared respectively;
S2: solution A, solution B, solution C, solution D, solution E, solution F, solution G and Solution H are poured into pot and stirs and adds Heat is to 78~85 DEG C;
S3: taking out after step S2 dissolution completely and pours into vacuum emulsification pot the inside is emulsified;
S4: taking out after the completion of step S3 emulsification can be prepared by skin care item.
The carbon atom that conventional microemulsions will use specific ester distribution is the saturation of 12-22 or the sucrose of unsaturated fatty acid Aliphatic ester, and the 1 valence alcohols for being 4-20 containing carbon atom number, form the composition of microemulsion.It can also be expanded by this method Temperature range stable greatly.But when using 1 small valence alcohols of carbon atom number, cosmetics can be made due to its distinctive smell Fragrance sense deteriorate, in addition, when using 1 big valence alcohols of carbon atom number, the oil sense that is had due to it, it is difficult to obtain as change The superior use feeling of cosmetic.Therefore, using lecithin, hydrolecithin, oil components, water as essential component, use is with lecithin The lipophilicity of rouge and the hydrophilic composite of hydrolecithin, and form the microemulsion of oil-in-water type.
Working principle: the microemulsified systems skin care item production technology, comprising the following steps: S1: prepare solution A respectively (solution A includes water 1, hydrolecithin, lecithin, water 2 and 1,2- pentanediol), (solution B includes water and hyaluronic acid to solution B Sodium), solution C (solution C includes water and acrylic acid esters co-polymer), solution D (solution D includes arginine), solution E (solution E packet Include ethylenediamine tetra-acetic acid), solution F (solution F include water, glycerol, Wild soybean, egg from, superoxide dismutase alcohol, glucan sulfuric acid Ester sodium, Phenoxyethanol, Sensiva SC50, sodium benzoate and potassium sorbate), (solution G includes butanediol, 1,2- penta 2 to solution G Alcohol, hydroxy phenylpropionyl amine benzoic acid and ascorbyl palmitate) and Solution H (Solution H includes pungent glycol and 1,2- hexylene glycol); S2: solution A, solution B, solution C, solution D, solution E, solution F, solution G and Solution H are poured into pot and are stirred and heated to 78~ 85℃;S3: taking out after step S2 dissolution completely and pours into vacuum emulsification pot the inside is emulsified;S4: it has been emulsified to step S3 It can be prepared by skin care item at rear taking-up.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention is defined by the appended.

Claims (10)

1. microemulsified systems skin care item, which is characterized in that including solution A, solution B, solution C, solution D, solution E, solution F, molten Liquid G and Solution H;
The solution A includes water 1, hydrolecithin, lecithin, water 2 and 1,2- pentanediol;
The solution B includes water and Sodium Hyaluronate;
The solution C includes water and acrylic acid esters co-polymer;
The solution D includes arginine;
The solution E includes ethylenediamine tetra-acetic acid;
The solution F include water, glycerol, Wild soybean, egg from, superoxide dismutase alcohol, dextran sulfate sodium, Phenoxyethanol, Sensiva SC50, sodium benzoate and potassium sorbate;
The solution G includes butanediol, 1,2- pentanediol, hydroxy phenylpropionyl amine benzoic acid and ascorbyl palmitate;
The Solution H includes pungent glycol and 1,2- hexylene glycol.
2. microemulsified systems skin care item according to claim 1, it is characterised in that: the water 1 in the solution A accounts for each molten The 87.78% of liquid percent of total, hydrolecithin, lecithin and water 2 account for each solution percent of total altogether in the solution A 0.6%, 1,2- pentanediol accounts for the 3% of each solution percent of total in the solution A.
3. microemulsified systems skin care item according to claim 1, it is characterised in that: the water in the solution B accounts for each molten The 4% of liquid percent of total, the Sodium Hyaluronate in the solution B account for the 0.04% of each solution percent of total.
4. microemulsified systems skin care item according to claim 1, it is characterised in that: the water in the solution C accounts for each molten The 2% of liquid percent of total, the acrylic acid esters co-polymer in the solution C account for the 1% of each solution percent of total.
5. microemulsified systems skin care item according to claim 1, it is characterised in that: the arginine in the solution D accounts for respectively The 0.15% of a solution percent of total.
6. microemulsified systems skin care item according to claim 1, it is characterised in that: the ethylenediamine tetrem in the solution E Acid accounts for the 0.03% of each solution percent of total.
7. microemulsified systems skin care item according to claim 1, it is characterised in that: water, glycerol, open country in the solution F Soybean, egg from, superoxide dismutase alcohol, dextran sulfate sodium, Phenoxyethanol, Sensiva SC50, sodium benzoate and sorb Sour potassium accounts for the 0.5% of each solution percent of total altogether.
8. microemulsified systems skin care item according to claim 1, it is characterised in that: butanediol in the solution G, 1,2- Pentanediol, hydroxy phenylpropionyl amine benzoic acid and ascorbyl palmitate account for the 0.5% of each solution percent of total altogether.
9. microemulsified systems skin care item according to claim 1, it is characterised in that: the pungent glycol and 1 in the Solution H, 2- hexylene glycol accounts for the 0.4% of each solution percent of total altogether.
10. the production technology of microemulsified systems skin care item according to claim 1, it is characterised in that: the following steps are included:
S1: solution A, solution B, solution C, solution D, solution E, solution F, solution G and Solution H are prepared respectively;
S2: solution A, solution B, solution C, solution D, solution E, solution F, solution G and Solution H are poured into pot and is stirred and heated to 78~85 DEG C;
S3: taking out after step S2 dissolution completely and pours into vacuum emulsification pot the inside is emulsified;
S4: taking out after the completion of step S3 emulsification can be prepared by skin care item.
CN201910404335.2A 2019-05-16 2019-05-16 Microemulsified systems skin care item production technology Pending CN110074994A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115590783A (en) * 2022-09-16 2023-01-13 上海百雀羚生物科技有限公司(Cn) Method for preparing oil-in-water type micro-emulsion by reverse emulsification and application of oil-in-water type micro-emulsion in cosmetics

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CN109157489A (en) * 2018-09-18 2019-01-08 梅淑婕 A kind of preparation method of skin care compositions and facial mask with antibacterial functions

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CN104739670A (en) * 2015-03-12 2015-07-01 广州澳希亚实业有限公司 Emulsion stabilizer for low-energy cosmetic composition and cosmetic composition
TW201742613A (en) * 2016-06-13 2017-12-16 波菲詩美妝有限公司 Percutaneous absorption promoting formulation, external composition for skin and microemulsion using thereof
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115590783A (en) * 2022-09-16 2023-01-13 上海百雀羚生物科技有限公司(Cn) Method for preparing oil-in-water type micro-emulsion by reverse emulsification and application of oil-in-water type micro-emulsion in cosmetics
CN115590783B (en) * 2022-09-16 2024-03-22 上海百雀羚生物科技有限公司 Method for preparing oil-in-water type micro emulsion by reverse emulsion and application of oil-in-water type micro emulsion in cosmetics

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Application publication date: 20190802