Reusable vacuum biological sample storage device and biological sample storage method
Technical Field
The invention relates to the technical field of medical equipment, in particular to a reusable vacuum biological sample storage device and a biological sample storage method.
Background
At present, the transportation of pathological samples or specimens after large hospital operations is mainly carried out by doctors to a pathology center through vacuum bags or separate specimen boxes, and the operation of the specimens which need to be vacuumized and soaked in formalin is more complicated. The dosage of formalin should be enough to facilitate the storage of the specimen. However, the excessive dosage of formalin will cause waste.
In the prior art, corresponding formalin liquid is matched according to the weight of a sample, and the operation process is complicated.
Therefore, how to simplify the operation flow to store the biological sample is a problem to be solved.
Disclosure of Invention
Therefore, the present invention has been made in view of the above problems, and the present invention solves the problem of complicated operation procedures for storing a biological sample in the prior art by skillful design of the infusion device and the sealing device. The invention realizes the aim through the following technical scheme:
the present invention provides a reusable vacuum biological sample storage device comprising: the sample box is arranged on the sample box body;
the sample box is arranged in the storage box and is a hollow cylinder with an open top end;
the sample lid sets up in the storage box, and sets up in the top of sample box, and the sample lid seals through the mode of rotatory screwing up with the sample box, and the sample lid includes: a screw cap, a sealing sheet, a filter screen and a liquid storage box;
the screw cap is arranged above the sample box, the screw cap is a hollow cylinder with two open ends, and the inner wall of the screw cap is provided with an annular sliding chute;
the sealing sheet is arranged inside the screw cap and below the annular sliding groove, and a first liquid outlet is formed in the sealing sheet;
the filter screen is arranged in the screw cap and below the sealing sheet;
the liquid storage box is a hollow cylinder, the bottom end of the liquid storage box is provided with a liquid outlet II, the top end of the liquid storage box is provided with a handle, the side wall of the cambered surface of the liquid storage box is provided with an annular bulge, the annular bulge is correspondingly inserted into the annular sliding groove, the liquid storage box and the screw cap are coaxially arranged, and the bottom surface of the liquid storage box is in close contact with the sealing sheet;
the tightening gripper is arranged above the sample cover and is driven by a power device;
the vacuum pumping pump is arranged in the storage box, one end of the vacuum pumping pump is connected with the air duct, and one end of the air duct extends into the storage box.
In one embodiment, the filter screen is arranged in a detachable manner.
In one embodiment, the sample cover is provided with a graduated scale.
In one embodiment, the screw cap outer wall is provided with a groove corresponding to the screw down grip.
In one embodiment, the distance from the center of the first liquid outlet to the axis of the sample cover is the same as the distance from the center of the second liquid outlet to the axis of the sample cover.
In one embodiment, the top end of the liquid storage box of the sample cover is provided with a motor.
In one embodiment, a plurality of liquid outlets are arranged on the sealing plate.
In one embodiment, a rubber ring is arranged in a gap between the screw cap and the liquid storage box.
In one embodiment, a secondary filter screen is arranged between the filter screen and the sealing sheet in the screw cap.
The invention also provides a biological sample storage method, and the reusable vacuum biological sample storage device adopting the technical scheme comprises the following steps:
the sample cover stored with the formalin solution is tightly grasped by a screwing hand (the formalin solution in the liquid storage box of the sample cover is in a vacuum environment after being processed in advance).
And secondly, placing the biological sample into the sample box, and completely closing the box door of the storage box.
And thirdly, the vacuum pump starts to work, and air in the storage box is pumped away, so that the required vacuum environment in the storage box is achieved.
And fourthly, the power device drives the screwing gripper to work, so that the sample cover and the sample box are screwed and sealed through rotation.
Fifthly, the sealed sample cover and the sample box are taken out, and the handle is manually screwed to enable the first liquid outlet and the second liquid outlet to correspond to each other, so that the formalin solution flows into the sample box.
Sixthly, the sealed accommodating box is placed into a specimen storage chamber to wait for the next inspection of medical staff.
And seventhly, the sample cover and the sample box are integrally inverted, so that the formalin solution in the sample box flows into the liquid storage box of the sample cover after being filtered by the filter screen, the handle is screwed, the first liquid outlet and the second liquid outlet are staggered, and the used formalin solution is recovered in the liquid storage box.
And rightly placing the sample cover and the sample box integrally, unscrewing the sample cover, taking out the biological sample, and cutting a small piece for inspection.
The invention has the following beneficial effects:
1. the ingenious design of the sample box and the sample cover structure of the invention ensures that the whole operation process is simpler, and simultaneously, the recovery of formalin solution is realized, so that the corresponding formalin liquid does not need to be matched according to the weight of the sample, and the formalin cannot be wasted due to excessive consumption.
2. When sampling and inspecting, the sample cover and the sample box are integrally inverted, so that formalin solution in the sample box flows into the sample cover, the harm of the formalin to medical personnel during sampling is reduced, and a biological sample is conveniently taken out.
Drawings
Fig. 1 is a schematic view of the overall structure of the storage box of the present invention.
Fig. 2 is a schematic view of the structure provided in the storage box of the present invention.
Fig. 3 is a schematic view of the overall structure of the combination of the sample case, the sample cover and the tightening hand grip of the present invention.
Fig. 4 is a schematic structural diagram of the sample box and the sample cover of the present invention.
Fig. 5 is a first schematic structural view of a screw-on cap arrangement of the sample cap of the present invention.
Fig. 6 is a second schematic structural view of the screw cap arrangement of the sample cap of the present invention.
Fig. 7 is a first structural schematic diagram of a liquid storage box of a sample cover according to the present invention.
Fig. 8 is a second schematic structural view of the liquid storage box of the sample cover of the present invention.
Figure 9 is a further detail view of the tightening grip of the present invention.
Fig. 10 is a schematic view of the top end of the reservoir of the sample cover of the present invention further provided with a motor.
Fig. 11 is a schematic structural view of the sealing sheet of the present invention further provided with a plurality of first liquid outlets.
Detailed Description
Preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings, so that those embodiments can be easily implemented by those having ordinary skill in the art to which the present invention pertains. However, the present invention may be embodied in many different forms and is not limited to the embodiments described below. In addition, in order to more clearly describe the present invention, components not connected to the present invention will be omitted from the drawings.
1-2, a reusable, evacuated biological sample storage device, comprising: the sample box comprises a storage box 1, a sample box 2, a sample cover 3, a tightening gripper 4 and a vacuum pump 5;
the sample box 2 is arranged in the storage box 1, and the sample box 2 is a hollow cylinder with an open top end;
the sample cover 3 is arranged in the storage box 1 and above the sample box 2, the sample cover 3 and the sample box 2 are sealed by screwing, wherein the contact edge of the sample cover 3 and the sample box 2 is provided with a rubber ring to enhance sealing, as shown in fig. 4-6, the sample cover 3 comprises: a screw cap 31, a sealing sheet 32, a filter screen 33 and a liquid storage box 34;
the screw cap 31 is arranged above the sample box 2, the screw cap 31 is a hollow cylinder with two open ends, and the inner wall of the screw cap is provided with an annular sliding groove 311;
the sealing sheet 32 is arranged inside the screw cap 31 and below the annular chute 311, and a first liquid outlet 321 is formed in the sealing sheet 32;
the filter screen 33 is arranged inside the screw cap 31 and below the sealing sheet 32;
as shown in fig. 7-8, the liquid storage box 34 is a hollow cylinder, the bottom end of the liquid storage box is provided with a second liquid outlet 341, the top end of the liquid storage box is provided with a handle 342, the side wall of the arc surface of the liquid storage box is provided with an annular protrusion 343, the annular protrusion 343 is correspondingly inserted into the annular sliding groove 311, the liquid storage box 34 and the screw cap 31 are coaxially arranged, wherein the bottom surface of the liquid storage box 34 is in close contact with the sealing sheet 32, and when the first liquid outlet 321 and the second liquid outlet 341 are completely staggered, the liquid storage box 34 of the sample cap 3 is;
the tightening gripper 4 is arranged above the sample cover 3, the tightening gripper 4 is driven by the power device 6, and the tightening gripper 4 is used for screwing and sealing the sample cover 3 and the sample box 2 in a rotating manner;
the vacuum pumping pump 5 is arranged in the storage box 1, one end of the vacuum pumping pump 5 is connected with the air duct 51, and one end of the air duct 51 extends into the storage box 1.
Preferably, as an implementation mode, the filter net 33 is arranged in a detachable mode, and the arrangement is convenient for cleaning and disinfection of the filter net 33.
Preferably, as an implementation mode, the sample cover 3 is provided with a graduated scale, which is configured to enable an appropriate amount of formalin solution in the sample cover 3 to flow into the sample box 2 according to the volume of the biological sample to be observed.
As shown in fig. 9, it is preferable that the screw cap 31 is provided with a groove 312 corresponding to the screw grip 4 on the outer wall, which facilitates the screw grip 4 to better screw the sample cap 3 to the sample box 2 by rotation.
Preferably, as an implementation mode, the distance from the center of the first liquid outlet 321 to the axis of the sample cover 3 is the same as the distance from the center of the second liquid outlet 341 to the axis of the sample cover 3, which is convenient for the first liquid outlet 321 and the second liquid outlet 341 to correspond to each other after the liquid storage box 34 rotates.
As shown in fig. 10, it is preferable that, as an implementation manner, the motor 344 is disposed at the top end of the liquid storage box 34 of the sample cover 3, and this arrangement enables the motor 344 to drive the liquid storage box 34 to rotate, and controls the correspondence and the interleaving of the first liquid outlet 321 and the second liquid outlet 341, so that the formalin solution can be poured into the sample box 2 before the vacuum pumping, i.e., regardless of the order of pouring the formalin solution into the sample box 2.
As shown in fig. 11, preferably, as an implementation mode, a plurality of liquid outlets 321 on the sealing plate 32 are provided, and this arrangement enables the formalin solution to flow into the sample box 2 relatively quickly.
Preferably, as an implementation mode, a rubber ring is arranged in a gap between the screw cap 31 and the liquid storage box 34, and the arrangement enables the whole sealing effect of the sample cover 3 to be better.
Preferably, as an implementation mode, a secondary filter is disposed between the filter screen 33 and the sealing sheet 32 in the screw cap 31, so that after the sample cap 3 and the sample box 2 are integrally inverted, the formalin solution in the sample box 2 can flow into the sample cap 3 after being subjected to secondary filtering, thereby further facilitating the recovery and utilization of the formalin solution.
The invention also provides a biological sample storage method, and the reusable vacuum biological sample storage device adopting the technical scheme comprises the following steps:
the sample cap 3 storing the formalin solution is grasped by tightening the grasping hand 4 (the formalin solution in the storage cassette 34 of the sample cap 3 is brought into a vacuum atmosphere after the process is performed in advance).
Secondly, the biological sample is placed in the sample box 2, and the door of the storage box 1 is completely closed.
And thirdly, the vacuum pumping pump 5 starts to work to pump away the air in the storage box 1, so that the required vacuum environment in the storage box 1 is achieved.
And fourthly, the power device 6 drives the screwing gripper 4 to work, so that the sample cover 3 and the sample box 2 are screwed and sealed through rotation.
Fifthly, the sealed sample cover 3 and the sample box 2 are taken out, the handle 342 is manually screwed, so that the first liquid outlet 321 corresponds to the second liquid outlet 341, and the formalin solution flows into the sample box 2.
Sixthly, the sealed accommodating box is placed into a specimen storage chamber to wait for the next inspection of medical staff.
Seventhly, the sample cover 3 and the sample box 2 are integrally inverted, so that formalin solution in the sample box 2 flows into the liquid storage box 34 of the sample cover 3 after being filtered by the filter screen 33, the handle 342 is screwed, the first liquid outlet 321 and the second liquid outlet 341 are staggered, and the used formalin solution is recovered in the liquid storage box 34.
And (iii) aligning the sample cover 3 and the sample box 2, unscrewing the sample cover 3, taking out the biological sample, and cutting small pieces for inspection.