CN110051807A - A kind of medical composition and its use for treating prostatic disorders - Google Patents
A kind of medical composition and its use for treating prostatic disorders Download PDFInfo
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- CN110051807A CN110051807A CN201910109439.0A CN201910109439A CN110051807A CN 110051807 A CN110051807 A CN 110051807A CN 201910109439 A CN201910109439 A CN 201910109439A CN 110051807 A CN110051807 A CN 110051807A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/235—Foeniculum (fennel)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/487—Psoralea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Chemical & Material Sciences (AREA)
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- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
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- Alternative & Traditional Medicine (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention provides a kind of pharmaceutical composition for treating prostatic disorders, raw material includes the component of following parts by weight: 35~65 parts of fennel seeds, 5~15 parts of fructus alpiniae oxyphyllae, 5~15 parts of psoralea corylifolia.Pharmaceutical composition warming and invigorating kidney Yang of the present invention, anti-inflammatory analgetic, can treat male urinary system disease.
Description
Technical field
The present invention relates to a kind of pharmaceutical compositions for treating prostatic disorders.
Background technique
Prostate is the accessory gland of male reproductive system, for azygous substantive body of gland, is located at bladder and triangular ligament
Between, urethra root is wrapped, shapes and sizes are like slightly flat chestnut.Upper end is roomy, and lower end is tapering, relatively flat behind body
It is smooth, close to rectum, can per rectum touch touch.Vertical diameter 3cm, transverse diameter 4cm, anteroposterior diameter 2cm weigh about 20g.Its size, function
It is largely dependent upon androgen.Children's prostate very little, sexual maturing period mushroom out；The elderly's glandular tissue is gradually degenerated,
Connective tissue proliferation in gland, forms hyperplasia of prostate, and urethra causes dysuria.
Summary of the invention
The present invention provides a kind of pharmaceutical composition for treating prostatic disorders, raw material includes the group of following parts by weight
Part:
35~65 parts of fennel seeds, 5~15 parts of fructus alpiniae oxyphyllae, 5~15 parts of psoralea corylifolia.
Further, raw material includes the component of following parts by weight:
45~55 parts of fennel seeds, 7~13 parts of fructus alpiniae oxyphyllae, 7~13 parts of psoralea corylifolia.
Further, raw material includes the component of following parts by weight:
50 parts of fennel seeds, 10 parts of fructus alpiniae oxyphyllae, 10 parts of psoralea corylifolia.
Wherein, raw material further includes 20~50 parts of salt；Further, salt is 30~40 parts；Further, salt is
35 parts.
Wherein, described pharmaceutical composition is oral drugs.
The present invention also provides the preparation methods of aforementioned pharmaceutical compositions, it includes following content: (1) taking raw material；(2) powder
It is broken；(3) it mixes.
The present invention also provides the preparation methods of aforementioned pharmaceutical compositions, it includes following content: (1) taking fennel seeds；(2)
Take fructus alpiniae oxyphyllae；(3) psoralea corylifolia is taken；(4) water or/and ethyl alcohol extract；(5) combined extract；(6) extracting solution and salt are taken, is prepared
Preparation.
The present invention also provides purposes of the aforementioned pharmaceutical compositions in the drug of preparation treatment prostatic disorders.
Wherein, the prostatic disorders are prostatitis or hyperplasia of prostate.
Prostatitis (prostatitis) refers to as caused by Various Complex reason, with urethral stimulant symptom and chronic basin
Chamber pain is the prostatic disorders of main clinical manifestation.
Hyperplasia of prostate (benign prostatic hyperplasia, BPH) is also known as hypertrophy of the prostate, hyperplasia body of gland position
In neck of urinary bladder, make urinary obstruction, cause frequent micturition and dysuria, seriously affect the quality of life of patient, is middle-aging male
Common disease, also known as benign prostatauxe, in Urology Surgery inpatient, it is only second to urolithiasis, occupies the 2nd.
Enruesis (Enuresis) is commonly called as wetting the bed, and is often referred to not urinate automatically when sleeping soundly.Meaning enruesis of the invention,
Do not limit patient age.
The present invention also provides purposes of the aforementioned pharmaceutical compositions in the drug of preparation treatment enruesis.
Pharmaceutical composition of the present invention, flavour of a drug are few, but therapeutic effect is extremely significant, and drug therapy is low in cost, Ke Yiyou
Effect reduces the cost of patient.
Specific embodiment
The specific embodiment of form by the following examples remakes further specifically above content of the invention
It is bright.But the range that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to example below.It is all to be based on above content of the present invention
The technology realized all belongs to the scope of the present invention.
Pharmaceutical composition drug activity of the present invention:
50 grams of fennel seeds are taken, 10 grams of fructus alpiniae oxyphyllae, 10 grams of psoralea corylifolia, is added water to cook 2 times, merges decocting liquid, adds in decocting liquid
Enter 35 grams of salt, dissolution, adult one day one secondary, and children are cut down according to the circumstance.
Effect: warming and invigorating kidney Yang, anti-inflammatory analgetic.
The major functions: 3 years old to 100 years old men and women grown-ups and children people, enruesis, urine diuresis fork, urine retention, urine wait, urinate urine have bubble
Foam；Prostatitis, hyperplasia of prostate etc.；Frequent micturition, the crymodynia enuresis, urgent urination.In inventor's career in medicine career, above-mentioned patient accepts for medical treatment altogether
More than 400 examples, cure rate reach 96%, effective percentage 100%；Also, the drug effect is fast, ordinary circumstance take one day can have it is bright
Aobvious to improve, continuous treatment 5-10 days, cure rate is 80% or more；Small number of patients healing time was at 15 days or more.
Typical case:
1994, Mr. Wang, male 20 years old or so, there is enruesis, took orally pharmaceutical composition of the present invention, once in the morning and once at night, that night
Do not break out, after continue to take half a month and have a surplus, fully recover.
Certain got up in the night to urinate 7-8 times petty official every night with prostatitis, column gland hypertrophy nearly 10 years, sees a doctor have no result outside.2016
Year August, takes pharmaceutical composition of the present invention, once in the morning and once at night, is just improved within 3rd~5, and medication half a month has a surplus, and fully recovers, after not
See recurrence.
Zhang, 90 is one-year-old, suffers from prostatitis hyperplasia, frequent micturition, while also taking pharmaceutical composition of the present invention with enruesis
Object 15 days, recovery from illness.
Embodiment 1
50 grams of fennel seeds are taken, 10 grams of fructus alpiniae oxyphyllae, 10 grams of psoralea corylifolia, is added water to cook 2 times, merges decocting liquid, adds in decocting liquid
Enter 35 grams of salt, dissolution is prepared into oral solution.
Embodiment 2
Take 40 grams of fennel seeds, 15 grams of fructus alpiniae oxyphyllae, 15 grams of psoralea corylifolia, 30 grams of salt.By fennel seeds, fructus alpiniae oxyphyllae, Psoralen cosmetics
After broken, mixed with salt, be prepared into powder.
Embodiment 3
60 grams of fennel seeds are taken, 7 grams of fructus alpiniae oxyphyllae, 7 grams of psoralea corylifolia, 70% ethyl alcohol extracts 2 times, merges alcohol extract, recycles ethyl alcohol
Alcohol extract is spare afterwards；The dregs of a decoction add water to cook 2 times, merge decocting liquid；Decocting liquid is merged with alcohol extract, add 25 grams of salt and
Suitable auxiliary material, is prepared into capsule.
Claims (10)
1. a kind of pharmaceutical composition for treating prostatic disorders, it is characterised in that: its raw material includes the component of following parts by weight:
35~65 parts of fennel seeds, 5~15 parts of fructus alpiniae oxyphyllae, 5~15 parts of psoralea corylifolia.
2. pharmaceutical composition according to claim 1, it is characterised in that: its raw material includes the component of following parts by weight:
45~55 parts of fennel seeds, 7~13 parts of fructus alpiniae oxyphyllae, 7~13 parts of psoralea corylifolia.
3. pharmaceutical composition according to claim 2, it is characterised in that: its raw material includes the component of following parts by weight:
50 parts of fennel seeds, 10 parts of fructus alpiniae oxyphyllae, 10 parts of psoralea corylifolia.
4. pharmaceutical composition according to any one of claims 1 to 3, it is characterised in that: its raw material further includes salt 20
~50 parts；Further, salt is 30~40 parts；Further, salt is 35 parts.
5. pharmaceutical composition according to any one of claims 1 to 3, it is characterised in that: described pharmaceutical composition is mouth
Medication object.
6. the preparation method of Claims 1 to 5 any one described pharmaceutical composition, it is characterised in that: it includes following content:
(1) raw material is taken；(2) it crushes；(3) it mixes.
7. the preparation method of claim 4~5 any one described pharmaceutical composition, it is characterised in that: it includes following content:
(1) fennel seeds are taken；(2) fructus alpiniae oxyphyllae is taken；(3) psoralea corylifolia is taken；(4) water or/and ethyl alcohol extract；(5) combined extract；(6) it takes and mentions
Liquid and salt are taken, preparation is prepared.
8. purposes of the Claims 1 to 5 any one described pharmaceutical composition in the drug of preparation treatment prostatic disorders.
9. purposes according to claim 8, it is characterised in that: the prostatic disorders are that prostatitis or prostate increase
It is raw.
10. purposes of the Claims 1 to 5 any one described pharmaceutical composition in the drug of preparation treatment enruesis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910109439.0A CN110051807A (en) | 2019-02-11 | 2019-02-11 | A kind of medical composition and its use for treating prostatic disorders |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910109439.0A CN110051807A (en) | 2019-02-11 | 2019-02-11 | A kind of medical composition and its use for treating prostatic disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110051807A true CN110051807A (en) | 2019-07-26 |
Family
ID=67316638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910109439.0A Pending CN110051807A (en) | 2019-02-11 | 2019-02-11 | A kind of medical composition and its use for treating prostatic disorders |
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| Country | Link |
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| CN (1) | CN110051807A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106606575A (en) * | 2016-12-27 | 2017-05-03 | 山东中医药大学 | Traditional Chinese medicine composition for treating night frequent micturition caused by geriatric male prostatitis diseases |
-
2019
- 2019-02-11 CN CN201910109439.0A patent/CN110051807A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106606575A (en) * | 2016-12-27 | 2017-05-03 | 山东中医药大学 | Traditional Chinese medicine composition for treating night frequent micturition caused by geriatric male prostatitis diseases |
Non-Patent Citations (6)
| Title |
|---|
| LIN MIAO等: "Bakuchiol exhibits anti-metastasis activity through NF-kB cross-talk signaling with AR and ERb in androgen-independent prostate cancer cells PC-3", 《JOURNAL OF PHARMACOLOGICAL SCIENCES》 * |
| 曹开镛: "《中医男科诊断治疗学》", 31 July 2007, 中国医药科技出版社 * |
| 李敏: "《图解妙方大全》", 31 January 2018, 中医古籍出版社 * |
| 罗兴洪等: "《古今药酒精粹》", 28 February 2018, 中国医药科技出版社 * |
| 胡维勒等: "《家有男科医生 原理前列腺炎》", 31 July 2018, 黑龙江科学技术出版社 * |
| 雪柏: "《家庭进补全书》", 31 March 1998, 辽宁科学技术出版社 * |
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| PB01 | Publication | ||
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Application publication date: 20190726 |
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| RJ01 | Rejection of invention patent application after publication |