CN110050929A - A kind of drinks with replenish the calcium, improve sleep and angst resistance effect - Google Patents
A kind of drinks with replenish the calcium, improve sleep and angst resistance effect Download PDFInfo
- Publication number
- CN110050929A CN110050929A CN201810052190.XA CN201810052190A CN110050929A CN 110050929 A CN110050929 A CN 110050929A CN 201810052190 A CN201810052190 A CN 201810052190A CN 110050929 A CN110050929 A CN 110050929A
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- CN
- China
- Prior art keywords
- calcium
- parts
- drinks
- acid
- solid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title claims abstract description 50
- 239000011575 calcium Substances 0.000 title claims abstract description 50
- 229910052791 calcium Inorganic materials 0.000 title claims abstract description 50
- 230000000694 effects Effects 0.000 title description 16
- 208000019901 Anxiety disease Diseases 0.000 title description 9
- 239000007787 solid Substances 0.000 claims abstract description 52
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 claims abstract description 44
- 229960003692 gamma aminobutyric acid Drugs 0.000 claims abstract description 22
- 239000007788 liquid Substances 0.000 claims abstract description 22
- OGNSCSPNOLGXSM-UHFFFAOYSA-N (+/-)-DABA Natural products NCCC(N)C(O)=O OGNSCSPNOLGXSM-UHFFFAOYSA-N 0.000 claims abstract description 21
- 235000020510 functional beverage Nutrition 0.000 claims abstract description 20
- 229960003495 thiamine Drugs 0.000 claims abstract description 17
- 239000011721 thiamine Substances 0.000 claims abstract description 17
- 239000000470 constituent Substances 0.000 claims abstract description 14
- 239000003651 drinking water Substances 0.000 claims abstract description 12
- 235000020188 drinking water Nutrition 0.000 claims abstract description 12
- 229960005069 calcium Drugs 0.000 claims description 47
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims description 18
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 14
- 150000001875 compounds Chemical class 0.000 claims description 14
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims description 13
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 9
- 229910021529 ammonia Inorganic materials 0.000 claims description 8
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 235000013355 food flavoring agent Nutrition 0.000 claims description 7
- 239000000796 flavoring agent Substances 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 5
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 claims description 4
- RWYRUDPAALLKPX-UHFFFAOYSA-N 2,2-difluoro-n-methylethanamine;hydrochloride Chemical compound Cl.CNCC(F)F RWYRUDPAALLKPX-UHFFFAOYSA-N 0.000 claims description 4
- OPSXJNAGCGVGOG-DKWTVANSSA-L Calcium L-aspartate Chemical compound [Ca+2].[O-]C(=O)[C@@H](N)CC([O-])=O OPSXJNAGCGVGOG-DKWTVANSSA-L 0.000 claims description 4
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 4
- 239000001749 Calcium fumarate Substances 0.000 claims description 4
- BCZXFFBUYPCTSJ-UHFFFAOYSA-L Calcium propionate Chemical compound [Ca+2].CCC([O-])=O.CCC([O-])=O BCZXFFBUYPCTSJ-UHFFFAOYSA-L 0.000 claims description 4
- JPIJQSOTBSSVTP-STHAYSLISA-N L-threonic acid Chemical compound OC[C@H](O)[C@@H](O)C(O)=O JPIJQSOTBSSVTP-STHAYSLISA-N 0.000 claims description 4
- 239000001110 calcium chloride Substances 0.000 claims description 4
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 4
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 claims description 4
- 239000001354 calcium citrate Substances 0.000 claims description 4
- 229940092124 calcium citrate malate Drugs 0.000 claims description 4
- 235000019296 calcium fumarate Nutrition 0.000 claims description 4
- 239000004227 calcium gluconate Substances 0.000 claims description 4
- 229960004494 calcium gluconate Drugs 0.000 claims description 4
- 235000013927 calcium gluconate Nutrition 0.000 claims description 4
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims description 4
- 235000010331 calcium propionate Nutrition 0.000 claims description 4
- 239000004330 calcium propionate Substances 0.000 claims description 4
- 235000011132 calcium sulphate Nutrition 0.000 claims description 4
- MKJXYGKVIBWPFZ-CEOVSRFSSA-L calcium;(2s)-2-hydroxypropanoate Chemical compound [Ca+2].C[C@H](O)C([O-])=O.C[C@H](O)C([O-])=O MKJXYGKVIBWPFZ-CEOVSRFSSA-L 0.000 claims description 4
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 claims description 4
- MPCMQXRREZMSPJ-UHFFFAOYSA-L calcium;2-hydroxybutanedioate;2-hydroxypropane-1,2,3-tricarboxylic acid;pentahydrate Chemical compound O.O.O.O.O.[Ca+2].[O-]C(=O)C(O)CC([O-])=O.OC(=O)CC(O)(C(O)=O)CC(O)=O MPCMQXRREZMSPJ-UHFFFAOYSA-L 0.000 claims description 4
- UZWMCCLZMHPPKW-UHFFFAOYSA-L calcium;2-oxopropanoate Chemical compound [Ca+2].CC(=O)C([O-])=O.CC(=O)C([O-])=O UZWMCCLZMHPPKW-UHFFFAOYSA-L 0.000 claims description 4
- 229960004203 carnitine Drugs 0.000 claims description 4
- 235000019700 dicalcium phosphate Nutrition 0.000 claims description 4
- 229940056902 l- threonic acid Drugs 0.000 claims description 4
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- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 claims description 3
- 239000001527 calcium lactate Substances 0.000 claims description 3
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- 235000011086 calcium lactate Nutrition 0.000 claims description 3
- BLORRZQTHNGFTI-ZZMNMWMASA-L calcium-L-ascorbate Chemical compound [Ca+2].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] BLORRZQTHNGFTI-ZZMNMWMASA-L 0.000 claims description 3
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- 235000003599 food sweetener Nutrition 0.000 claims description 3
- HLIAVLHNDJUHFG-HOTGVXAUSA-N neotame Chemical compound CC(C)(C)CCN[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 HLIAVLHNDJUHFG-HOTGVXAUSA-N 0.000 claims description 3
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- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims 2
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- DWNBOPVKNPVNQG-LURJTMIESA-N (2s)-4-hydroxy-2-(propylamino)butanoic acid Chemical compound CCCN[C@H](C(O)=O)CCO DWNBOPVKNPVNQG-LURJTMIESA-N 0.000 description 3
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Non-Alcoholic Beverages (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The embodiment of the invention provides a kind of solid drinks, remembered with parts by weight, include following components: 20-80 parts of calcium constituent, 3-50 parts of γ-aminobutyric acid and 3-40 parts of L-thiamine, it to include the solid drinks and drinking water that the embodiment of the invention also provides a kind of liquid functional beverages.Solid and liquid functional beverage provided in an embodiment of the present invention, which has, replenishes the calcium, improves sleep, antianxiety and other effects.
Description
Technical field
The present invention relates to a kind of drinks fields, in particular to one kind, which has, replenishes the calcium, improves sleep and angst resistance effect
Drinks.
Background technique
γ-aminobutyric acid is a kind of naturally occurring non-protein composition amino acid, is distributed widely in animal and plant body.Plant
All contain γ-aminobutyric acid in such as Macroptilium, the seed of ginseng category Chinese herbal medicine, rhizome and tissue fluid.In animal body, gamma-amino
Butyric acid almost exists only in nerve fiber, and the content in mesencephalic tissue is about 0.1-0.6mg/ grams of tissue, and immunology is ground
Study carefully and shows that the highest region of its concentration is big substantia nigra.γ-aminobutyric acid is inhibition mind critically important in central nervous system
Through mediator, there is extremely important physiological function, such as blood pressure lowering promotes kidney Fitness improvement and protective effect, inhibit fatty liver and
Obesity, activation liver function etc..The micro γ-aminobutyric acid of daily iron supplement is conducive to the alleviation of heart and brain blood pressure, and can promote people
The balance of vivo acid metabolism, adjusts immune function.γ-aminobutyric acid belongs to strong neural inhibitory aminoacid, and effect is to reduce
Neuronal activity plays calmness, hypnosis, anticonvulsant function.Gabanergic combines brain receptor antianxity and is allowed to sharp
It is living, it then acts synergistically with other substance, prevents information relevant to anxiety from arriving at brain and indicate maincenter, play antianxity
Physiological action.γ-aminobutyric acid can enter intracerebral tricarboxylic acid cycle, promote brain cell metabolism, while can also improve glucose generation
The activity of glucose phosphate esterase when thanking increases the generation of acetylcholine, and expansion blood vessel increases blood flow, and reduces blood ammonia, promotees
Into the metabolism of brain, restore function of brain cell.
L-thiamine is distinctive free amino acid in tealeaves, pleasantly sweet, chemical structure and intracerebral active material paddy acyl
Amine, glutamic acid are similar, are the main ingredient for promoting the production of body fluid in tealeaves and moistening sweet tea, the 1%-2% of weight is accounted in dry tea.L-thiamine can be with
Mesencephalic centre dopamine D_2 receptors are obviously promoted, intracerebral dopamine physiological activity is improved.Dopamine is a kind of activation cranial nerve cell
The emotion state of central neurotransmitter, physiological activity and people are closely related.People feel to loosen when drinking tea, tranquil, mood
It is happy, have proven to the effect of mainly L-thiamine.Certainly antifatigue effect of drinking tea is recognized as to a certain extent from this
One effect.Yokogoshi et al. confirmed that taking L-thiamine will have a direct impact on and learn, remembers again in their some experiments
Recall the activity of related intracerebral central neurotransmitter serotonin, improves learning ability and memory.
L-Trp is a kind of essential amino acid.Serotonin, niacin, melatonin, pine nut can be changed into vivo
The several physiological active substances such as body hormone and xanthurenic acid (4,8-Er Qiangjikuilinjiasuan).When human body lacks tryptophan, it can not only cause general low albumen disease, also
The special illnesss such as dermatopathy, cataract, vitreum degeneration and myocardial fibrosis can be generated.It can also enhance body and penetrate to γ-
The resistance of line.The every minimum daily requirement of human body is 0.2 gram.L-Trp is human nutrition enriching substance, and antioxidant is usually used in
Maternal nutritional tonic and the special milk powder of newborn child are used for pellagra (pellagra) medicine, or as sedative, adjust essence
The refreshing rhythm and pace of moving things improves sleep.
L-tyrosine is a kind of important nutritional necessary amino acid, plays to metabolism, the growth and development of humans and animals
Important role is widely used in the industries such as food, feed, medicine and chemical industry, and the nutrition frequently as phenylketonuria patient is mended
Fill agent.Since l-tyrosine has adjusting mood, the effect of nervous system is stimulated, in the insufficient situation of l-tyrosine, human body
It cannot be metabolized phenylalanine well.Lacking both amino acid will cause phrenoblabia, generate anxiety, depression, male's sexual desire
It is low, with the health problems such as confirmed fatigue.
Calcium is element needed by human, referred to as " biological element ".For human body, no matter muscle, nerve, body fluid and bone
In, all useful Ca2+In conjunction with protein.Calcium is mankind's bone, the main inorganic composition of tooth and neurotransmission, contraction of muscle, blood
The necessary elements such as liquid condensation, hormone release and galactosis.Calcium accounts for about the 1.4% of body mass, participates in metabolism, often
It must be supplemented with calcium.Calcium is the activator of more than 200 kinds of enzymes in human body, enables each organ normal operation of human body.Calcium can help to adjust
Save nervous system, insomnia, hypertension, premenstrual cramp, cold, even to feel overstretched be also likely to be the mark of calcium deficiency.
Currently on the market, other than dairy products, almost without the drinks for the purpose of replenishing the calcium.Meanwhile with people
Rhythm of life be getting faster, life and work pressure increasingly increases, and the following anxiety, anxiety, agitation, insomnia seriously affect
To our study and work, go back Eroded our health and mental health.It is anxious for this part population
Need it is a be suitable for daily drinking, sleep can be improved and play the drinks of angst resistance effect.
Summary of the invention
The purpose of the present invention is to provide a kind of drinks, for by supplement calcium and γ-aminobutyric acid (GABA),
The amino acid such as L-thiamine reach and replenish the calcium and improve sleep, physiological function antianxity.Specific technical solution is as follows:
The present invention provides a kind of solid drinks, is remembered with parts by weight, includes following components: 20-80 parts of calcium constituent, γ-
3-50 parts and L-thiamine 3-40 parts of aminobutyric acid；Preferably, calcium constituent 30-70 parts, 10-40 parts of γ-aminobutyric acid and L- tea
10-30 parts of propylhomoserin；It is highly preferred that 40-60 parts of calcium constituent, 30 parts and 15 parts of L-thiamine of γ-aminobutyric acid.
Calcium constituent in solid drinks of the present invention is from soluble easily in water or subacid solution calcium containing compound.
Calcium containing compound in solid drinks of the present invention is selected from calcium chloride, calcium glycine, calcium gluconate, a left side
Revolve carnitine calcium fumarate, calcium lactate, L-calcium lactate, l threonic acid, ASPARTIC ACID calcium, calcium acetate, calcium propionate, vitamin
At least one of C calcium, CALCIUM PYRUVIC, calcium sulfate, calcium monohydrogen phosphate, calcium citrate, calcium citrate malate.
Solid drinks of the present invention, are remembered with parts by weight, also comprising L-Trp 10-50 parts and l-tyrosine 10-
50 parts；Preferably, L-Trp 15-30 parts and l-tyrosine 15-30 parts；It is highly preferred that 20 parts of L-Trp and l-tyrosine
20 parts.
Solid drinks of the present invention also include flavoring agent.
Flavoring agent in solid drinks of the present invention includes neotame sweetener and/or citric acid acid.
The present invention also provides a kind of liquid functional beverages, include the solid drinks and drinking water.It is wherein solid
The quality of body function beverage and the ratio of drinking water volume are as follows: 1:(50-500) g/mL.
Drinks provided in an embodiment of the present invention, the calcium constituent for including have effects that replenish the calcium, γ-aminobutyric acid and L-
Theanine can help human body to adjust nervous system, and elimination is nervous, and make one calm, be easy to fall asleep, l-tyrosine and L- color
Propylhomoserin also has effects that tranquilizing the mind is antianxity, and therefore, drinks provided by the present invention, which have, replenishes the calcium, improves sleep and anti-coke
Worry effect.Further, drinks provided by the embodiment of the present invention also have anticonvulsion, antianxiety, blood pressure lowering blood ammonia,
Improve the physiological action of learning ability and memory.Certainly, implementing any of the products of the present invention must be not necessarily required to reach simultaneously
All the above advantage.
Specific embodiment
L-thiamine has the ability to pass through blood absorption and enters brain.Once L-thiamine help stimulates production into brain
Raw γ-aminobutyric acid, therefore induce calm and comfortable feeling.In addition inventors have found that for certain crowds, L-Trp
It is used together with l-tyrosine, L-Trp either than l-tyrosine is used alone, and for mitigating depression, effect will be more
It is good.When therefore being related to adding amino acid composition in the present invention, γ-aminobutyric acid and L-thiamine always occur in pairs；L- color
Propylhomoserin and l-tyrosine always occur in pairs.
First aspect present invention provides a kind of solid drinks, is remembered with parts by weight, includes following components: calcium constituent
20-80 parts, 3-50 parts of γ-aminobutyric acid and 3-40 parts of L-thiamine；Preferably, calcium constituent 30-70 parts, γ-aminobutyric acid 10-
40 parts and L-thiamine 10-30 parts；It is highly preferred that 40-60 parts of calcium constituent, 30 parts and 15 parts of L-thiamine of γ-aminobutyric acid.
In some specific embodiments of first aspect present invention, the calcium constituent comes from soluble easily in water or subacid solution
Calcium containing compound.It is of the present invention it is " soluble easily in water " refer to substance at 20 DEG C, solubility in water 1g/100g water with
On." subacid solution " of the present invention refers to 25 DEG C, the aqueous solution of 3≤pH < 7." being soluble in subacid solution " of the present invention,
Refer to 20 DEG C, the solubility of any pH of the substance within the scope of the pH of the subacid solution is more than 1g/100g subacid solution.
In some specific embodiments of first aspect present invention, the calcium containing compound is selected from calcium chloride, glycine
Calcium, calcium gluconate, Levulorotation carnitine calcium fumarate, calcium lactate, L-calcium lactate, l threonic acid, ASPARTIC ACID calcium, acetic acid
Calcium, calcium propionate, calcium ascorbate, CALCIUM PYRUVIC, calcium sulfate, calcium monohydrogen phosphate, calcium citrate, in calcium citrate malate at least
It is a kind of；Wherein, in the calcium containing compound, calcium chloride, calcium glycine, calcium gluconate, Levulorotation carnitine calcium fumarate, lactic acid
Calcium, L-calcium lactate, l threonic acid, ASPARTIC ACID calcium, calcium acetate, calcium propionate, calcium ascorbate etc. belong to soluble easily in water
Calcium containing compound；CALCIUM PYRUVIC, calcium sulfate, calcium monohydrogen phosphate, calcium citrate, calcium citrate malate etc. belong to be soluble in it is slightly sour molten
The calcium containing compound of liquid.Common food addition calcium containing compound, can be used as solid drinks calcic of the present invention
Compound is alternative, and this will not be repeated here.
Solid drinks provided by the present invention, can be by taking the one or any of several of the calcium containing compound
Combination, so that calcium element content is in 200mg-800mg in solid drinks, with γ-aminobutyric acid 30-500mg and L- tea ammonia
Sour 30-400mg is uniformly mixed, and forms a series of solid drinks.
To further increase the antidepressant function of solid drinks of the present invention, including aforesaid solid drinks
On the basis of ingredient, remembered with parts by weight, also comprising L-Trp 10-50 parts and l-tyrosine 10-50 parts；Preferably, L- color ammonia
Sour 15-30 parts and l-tyrosine 15-30 parts；It is highly preferred that 20 parts and 20 parts of l-tyrosine of L-Trp.
In another specific embodiment of first aspect present invention, one kind or any several of the calcium containing compound is taken
Kind combination, make its calcium element content in 200mg-800mg, with γ-aminobutyric acid 30-500mg, L-thiamine 30-400mg,
L-Trp 100-500mg and l-tyrosine 100-500mg is uniformly mixed, and forms a series of solid drinks.
It, can also be in solid function provided by first aspect present invention in order to improve the mouthfeel of above-mentioned solid drinks
Common food flavoring agent is added in beverage, the flavoring agent is including but not limited to neotame sweetener and citric acid acid.
Second aspect of the present invention provides a kind of liquid functional beverage, may include appointing for first aspect present invention offer
One solid drinks and drinking water.It, can be by the solid function described in first aspect present invention in implementation process of the present invention
Beverage is dissolved in the water and liquid functional beverage provided by the invention is made.
In some specific embodiments of second aspect of the present invention, the quality of solid drinks and drinking water volume
Than are as follows: 1:(50-500) g/mL.For example, the solid drinks of 1-5g can be dissolved in 250-500mL drinking water, this is formed
The liquid functional beverage of invention.
In the above-mentioned technical proposal that the present invention provides, solid drinks transportation cost is low, and is convenient for carrying, it is only necessary to
It is dissolved with drinking water i.e. drinkable.Liquid functional beverage, which is uncapped, to be drunk, convenient when drink.
Involved calcium containing compound, amino acid, flavoring agent etc. in solid drinks provided by the present invention
It buys from commercial channels.
Technical solution of the present invention is described below in conjunction with specific embodiment, described embodiment is only this
Invention a part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art exist
Every other embodiment obtained under the premise of creative work is not made, shall fall within the protection scope of the present invention.
Drinks prepare embodiment
Embodiment 1, the preparation of solid drinks:
It is formulated as follows:
Preparation method:
Above-mentioned each component is weighed, takes lesser two component of weight to be first uniformly mixed, then adds the slightly heavy third of weight
Component is uniformly mixed, and so on, it is gradually mixed, is mixed according to weight is ascending, pack.
Embodiment 2, the preparation of liquid functional beverage:
It is formulated as follows:
Preparation method:
Above-mentioned each component is weighed, takes lesser two component of weight to be first uniformly mixed, then adds the slightly heavy third of weight
Component is uniformly mixed, and so on, it is gradually mixed according to weight is ascending, mixes, be dissolved in 250mL drinking water, filled
Bottle.
Embodiment 3, the preparation of solid drinks:
By the preparation method of embodiment 1, prepared using formula as below:
Embodiment 4, the preparation of liquid functional beverage:
By the preparation method of embodiment 2, prepared using formula as below:
Embodiment 5, the preparation of solid drinks:
By the preparation method of embodiment 1, prepared using formula as below:
Embodiment 6, the preparation of liquid functional beverage:
By the preparation method of embodiment 2, prepared using formula as below:
Embodiment 7, the preparation of solid drinks:
By the preparation method of embodiment 1, prepared using formula as below:
Embodiment 8, the preparation of liquid functional beverage:
By the preparation method of embodiment 2, prepared using formula as below:
Embodiment 9, the preparation of solid drinks:
By the preparation method of embodiment 1, prepared using formula as below:
Embodiment 10, the preparation of liquid functional beverage:
By the preparation method of embodiment 2, prepared using formula as below:
Embodiment 11, the preparation of solid drinks:
By the preparation method of embodiment 1, prepared using formula as below:
Embodiment 12, the preparation of liquid functional beverage:
By the preparation method of embodiment 2, prepared using formula as below:
Embodiment 13, the preparation of solid drinks:
By the preparation method of embodiment 1, prepared using formula as below:
Embodiment 14, the preparation of liquid functional beverage:
By the preparation method of embodiment 2, prepared using formula as below:
Embodiment 15, the preparation of solid drinks:
By the preparation method of embodiment 1, prepared using formula as below:
Embodiment 16, the preparation of liquid functional beverage:
By the preparation method of embodiment 2, prepared using formula as below:
Embodiment 17, the preparation of solid drinks:
By the preparation method of embodiment 1, prepared using formula as below:
Embodiment 18, the preparation of liquid functional beverage:
By the preparation method of embodiment 2, prepared using formula as below:
Embodiment 19, the preparation of solid drinks:
By the preparation method of embodiment 1, prepared using formula as below:
Embodiment 20, the preparation of liquid functional beverage:
By the preparation method of embodiment 2, prepared using formula as below:
Embodiment 21, the preparation of solid drinks:
By the preparation method of embodiment 1, prepared using formula as below:
After being mixed according to method described in embodiment 1,1000 bags of weight packaging, every bag of net content 2.064g.
Embodiment 22, the preparation of liquid functional beverage:
By the preparation method of embodiment 2, prepared using formula as below:
It after being mixed according to method as described in example 2, is dissolved in 350L drinking water, bottles, every bottle of 350mL.
Sleep quality improves evaluation experimental
Influence of the drinks provided by the present invention of embodiment 22 to sleep quality
1. experimental subjects
The age is chosen between 40-70 years old, identifies oneself the Benxi, Liaoning citizen of poor sleep, amounts to 100 people, by candidate
Two groups of A, B are randomly divided into, every group of 50 people.
2. experimental method
Sleep quality is evaluated using Pittsburg Sleep Quality Index scale (PSQI), for evaluating subject nearest 1 month
Sleep quality.Analysis indexes include sleep quality, time for falling asleep, sleeping time, Sleep efficiency, sleep disturbance, hypnotic drug,
Score by 0~3 grade by totally 7 factors, each factor for daytime function obstacle, and accumulating each factor score is PSQI total score, total score model
Enclosing is 0~21 point, and score is higher, indicates that sleep quality is poorer.Clinically value, total score≤7 PSQI usually are defined for reference with 7 points
It is divided into normally, total score >=8 point PSQI are sleep disturbance.
100 candidates respectively fill in PSQI table (the results are shown in Table before testing in 1) when experiment starts, and it is solid that everyone gets A group
30 parts of body function beverage (component contained by every part is shown in embodiment 1), calcium glycine is free of in the solid drinks that B group is got,
His component is identical as A group, and two groups of solid drinks outer packings got are consistent.Candidate is required to drink daily a solid
State beverage, i.e., early daily that solid beverage is dissolved in 200mL, is drunk in 25-40 DEG C of drinking water after meal, experiment terminates after 30 days, then
It is secondary to fill in PSQI table (the results are shown in Table after testing in 1).
3. experimental result
1 sleep quality experimental result of table
For in A group, the candidate of score >=8 drinks drinks provided by the present invention, after 30 days daily
PSQI score is substantially reduced, and illustrates that this drinks has facilitation to sleep quality is improved；Unexpectedly, with B group score
>=8 candidate compares, and at the end of experiment, the fall of score is significantly greater than B to the candidate of A group score >=8
Group illustrates in solid drinks of the present invention, contains Calcium compounds due to joined, to the improvement result ratio of sleep quality
It is more obvious using amino acid composition merely.
It is suitable for supplementing the calcium and amino acid that needed by human body is wanted to provided by the present invention above, replenishes the calcium, changes to reach
The drinks of kind sleep and angst resistance effect are described in detail.Specific embodiment used herein is to reality of the invention
The mode of applying is expounded, method and its central idea of the invention that the above embodiments are only used to help understand.It answers
It, for those of ordinary skill in the art, without departing from the principle of the present invention, can also be to the present invention when pointing out
Some improvement and modification can also be carried out, these improvement and modification also fall into the protection of the claims in the present invention.
Claims (8)
1. a kind of solid drinks, which is characterized in that remembered with parts by weight, include following components: 20-80 parts of calcium constituent, γ-ammonia
3-50 parts and L-thiamine 3-40 parts of base butyric acid；Preferably, calcium constituent 30-70 parts, 10-40 parts of γ-aminobutyric acid and L- tea ammonia
It is 10-30 parts sour；It is highly preferred that 40-60 parts of calcium constituent, 30 parts and 15 parts of L-thiamine of γ-aminobutyric acid.
2. solid drinks according to claim 1, which is characterized in that the calcium constituent is from soluble easily in water or slightly sour
The calcium containing compound of solution.
3. solid drinks according to claim 2, it is characterised in that the calcium containing compound is selected from calcium chloride, sweet ammonia
Sour calcium, calcium gluconate, Levulorotation carnitine calcium fumarate, calcium lactate, L-calcium lactate, l threonic acid, ASPARTIC ACID calcium, vinegar
Sour calcium, calcium propionate, calcium ascorbate, CALCIUM PYRUVIC, calcium sulfate, calcium monohydrogen phosphate, calcium citrate, in calcium citrate malate extremely
Few one kind.
4. solid drinks according to claim 1, which is characterized in that remembered with parts by weight, also include L-Trp 10-
50 parts and l-tyrosine 10-50 parts；Preferably, L-Trp 15-30 parts and l-tyrosine 15-30 parts；It is highly preferred that L- color ammonia
20 parts and 20 parts of l-tyrosine of acid.
5. solid drinks described in -4 according to claim 1, which is characterized in that also include flavoring agent.
6. solid drinks according to claim 5, it is characterised in that the flavoring agent include neotame sweetener and/or
Citric acid acid.
7. a kind of liquid functional beverage, which is characterized in that comprising solid drinks of any of claims 1-6 and
Drinking water.
8. liquid functional beverage as claimed in claim 7, which is characterized in that the quality and drinking water volume of solid drinks
Ratio are as follows: 1:(50-500) g/mL.
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| CN201810052190.XA CN110050929A (en) | 2018-01-19 | 2018-01-19 | A kind of drinks with replenish the calcium, improve sleep and angst resistance effect |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111453831A (en) * | 2020-05-11 | 2020-07-28 | 浙江养生堂天然药物研究所有限公司 | Drinking water for improving sleep quality |
| CN114732132A (en) * | 2020-12-21 | 2022-07-12 | 北京朗迪制药有限公司 | Calcium-magnesium niacin liquid nutrient supplement for improving sleep and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102379343A (en) * | 2010-09-06 | 2012-03-21 | 李洪亮 | Gamma-aminobutyric acid-containing milk beverage and production method thereof |
| CN103054044A (en) * | 2012-12-26 | 2013-04-24 | 北京康比特体育科技股份有限公司 | Sleep-improving health food composition |
| CN103609944A (en) * | 2013-12-10 | 2014-03-05 | 南通励成生物工程有限公司 | Blood pressure reducing and sleeping promoting health-care food |
| CN105942533A (en) * | 2016-06-29 | 2016-09-21 | 成都博创必成医药技术有限公司 | Functional beverage and functional beverage effervescent tablet |
| CN106723021A (en) * | 2016-11-28 | 2017-05-31 | 武汉哈福科技有限公司 | A kind of functional food for improving the health care of sleep |
-
2018
- 2018-01-19 CN CN201810052190.XA patent/CN110050929A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102379343A (en) * | 2010-09-06 | 2012-03-21 | 李洪亮 | Gamma-aminobutyric acid-containing milk beverage and production method thereof |
| CN103054044A (en) * | 2012-12-26 | 2013-04-24 | 北京康比特体育科技股份有限公司 | Sleep-improving health food composition |
| CN103609944A (en) * | 2013-12-10 | 2014-03-05 | 南通励成生物工程有限公司 | Blood pressure reducing and sleeping promoting health-care food |
| CN105942533A (en) * | 2016-06-29 | 2016-09-21 | 成都博创必成医药技术有限公司 | Functional beverage and functional beverage effervescent tablet |
| CN106723021A (en) * | 2016-11-28 | 2017-05-31 | 武汉哈福科技有限公司 | A kind of functional food for improving the health care of sleep |
Non-Patent Citations (3)
| Title |
|---|
| 徐元贞: "《新全实用药物手册 第3版》", 28 February 2005, 河南科学技术出版社 * |
| 曾志锋: "《医生向左 病人往右 最新版》", 28 February 2013, 四川科学技术出版社 * |
| 郑建仙: "《功能性食品学》", 30 June 2009, 中国轻工业出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111453831A (en) * | 2020-05-11 | 2020-07-28 | 浙江养生堂天然药物研究所有限公司 | Drinking water for improving sleep quality |
| CN114732132A (en) * | 2020-12-21 | 2022-07-12 | 北京朗迪制药有限公司 | Calcium-magnesium niacin liquid nutrient supplement for improving sleep and preparation method thereof |
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Application publication date: 20190726 |