CN110037827A - The Implantable medical device that transfer ability reduces - Google Patents
The Implantable medical device that transfer ability reduces Download PDFInfo
- Publication number
- CN110037827A CN110037827A CN201910271217.9A CN201910271217A CN110037827A CN 110037827 A CN110037827 A CN 110037827A CN 201910271217 A CN201910271217 A CN 201910271217A CN 110037827 A CN110037827 A CN 110037827A
- Authority
- CN
- China
- Prior art keywords
- medical device
- implantable medical
- bracket
- covering part
- unmasked portion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
- A61F2002/009—Special surfaces of prostheses, e.g. for improving ingrowth for hindering or preventing attachment of biological tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2002/9528—Instruments specially adapted for placement or removal of stents or stent-grafts for retrieval of stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0059—Additional features; Implant or prostheses properties not otherwise provided for temporary
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a kind of medical device and the methods for making and using medical device.Medical device of demonstrating may include Implantable medical device.The Implantable medical device may include the bracket with covering part and unmasked portion.Covering part is releasably attached to unmasked portion.The lid component can be arranged along covering part.Unmasked portion may include the release tab for being designed to discharge unmasked portion from covering part.Removing components may be coupled to covering part to help to remove covering part from implant site.
Description
The application be on January 14th, 2016 " transfer ability reduce Implantable medical device " submitting, entitled,
Application No. is the divisional applications of the application of 201680010573.X.
Cross reference to related applications
According to 35U.S.C. § 119 (e), this application claims the U.S. Provisional Application No.62/ submitted on January 16th, 2015
104,356 priority, entire contents are incorporated herein by reference.
Technical field
The invention belongs to medical device and the methods for manufacturing medical device.More specifically, the invention belongs to transfer ability drops
Low elongated Implantable medical device.
Background technique
Have been developed that it is various medical, for example, the intravascular internal medical device used.It is some in these devices
Including seal wire, conduit, bracket etc..These devices manufacture by any one of various different manufacturing methods and can bases
Any one of various methods carry out using.
Summary of the invention
Present disclose provides the design of medical device, material, manufacturing method and use alternative solution.A kind of demonstration medical treatment dress
Setting may include Implantable medical device, which includes:
Bracket with covering part and unmasked portion；
Wherein covering part is releasably attached to unmasked portion；
Along the The lid component of covering part setting；
Wherein unmasked portion includes release tab, which discharges at by unmasked portion from covering part
It opens；With
Covering part is attached to help the removing components for removing covering part from implant site.
Alternately or additionally as any of the above-described embodiment, the covering part of bracket includes braided fabric.
Alternately or additionally as any of the above-described embodiment, the unmasked portion of bracket includes crocheted line.
Alternately or additionally as any of the above-described embodiment, the unmasked portion of bracket is made of solid wire.
Alternately or additionally as any of the above-described embodiment, the unmasked portion of bracket is configured to allow for tissue into it
It grows to reduce the migration of bracket.
Alternately or additionally as any of the above-described embodiment, covering part, unmasked portion or both have horn-like
End regions.
Alternately or additionally as any of the above-described embodiment, proximally drawing discharges the non-covering part that tab disassembles bracket
Point.
Alternately or additionally as any of the above-described embodiment, proximally pulling release tab makes the unmasked portion of bracket
It is separated from from the covering part of bracket.
Alternately or additionally as any of the above-described embodiment, The lid component is designed to that tissue covering along bracket is greatly reduced
Cover ingrowing.
Alternately or additionally as any of the above-described embodiment, the unmasked portion of bracket includes biodegradable material
Material.
Alternately or additionally as any of the above-described embodiment, removing components include being arranged around the covering part of bracket
Suture.
Disclosed herein is a kind of Implantable medical devices.The Implantable medical device includes:
Bracket with knitted parts and crocheted part；
Wherein knitted parts are releasably attached to crocheted part；With
Along the The lid component of knitted parts setting；
Wherein The lid component is designed to limitation tissue along knitted parts ingrowing；And
Wherein the crocheted part of bracket is configured to allow for tissue to be grown into it to reduce the migration of bracket.
Alternately or additionally as any of the above-described embodiment, the crocheted part of bracket is made of solid wire.
Alternately or additionally as any of the above-described embodiment, knitted parts, crocheted part or both have horn-like end
Portion region.
Alternately or additionally as any of the above-described embodiment, removing components are attached to knitted parts to help from implanting portion
Displacement removes knitted parts.
Alternately or additionally as any of the above-described embodiment, crocheted part includes release tab, and wherein proximally
It pulls the crocheted part of release tab dismantling bracket and is separated from the crocheted part of bracket from the knitted parts of bracket.
Alternately or additionally as any of the above-described embodiment, The lid component is designed to the volume that tissue is greatly reduced along bracket
Knit part ingrowing.
Alternately or additionally as any of the above-described embodiment, the crocheted part of bracket is configured to allow for tissue raw into it
The long migration to reduce bracket.
Alternately or additionally as any of the above-described embodiment, the crocheted part of bracket includes biodegradable material.
Disclosed herein is the methods for removing Implantable medical device.This method comprises:
Made to discharge tab engagement bracket with the first removing components, the stenter to implant is in implant site；
Wherein bracket includes:
Knitted parts；
It is releasably attached to the crocheted part of knitted parts；With
Along the The lid component of knitted parts setting；
Proximally retraction release tab is to disassemble crocheted part and discharge crocheted part from knitted parts；
Make the knitted parts of removing components engagement bracket with the second removing components；With
The knitted parts of bracket are removed from implant site.
The general introduction of above-mentioned some embodiments is not intended to describe each disclosed embodiment of the disclosure or every kind of embodiment party
Formula.These embodiments are more specifically illustrated in the following drawings and specific embodiment.
Detailed description of the invention
In conjunction with attached drawing, consider that the present invention can be more fully understood in following specific embodiments, in which:
Fig. 1 is the side view of demonstration Implantable medical device；
Fig. 2 shows a part of demonstration Implantable medical device；
Fig. 3 shows the demonstration Implantable medical device along body cavity implantation；
Fig. 4-5 shows a part of the process of the section of dismantling demonstration Implantable medical device；With
Fig. 6 shows a part that the process of section of demonstration Implantable medical device is removed from body cavity.
Although the present invention can various modifications may be made and alternative form, its details is exemplified via the demonstration in attached drawing,
And it will be described in detail.However, it should be understood that the disclosure is not limited to the specific embodiment by the present invention.On the contrary, this hair
It is bright to cover all remodeling, equivalent and the alternative form fallen within the spirit and scope of the invention.
Specific embodiment
For term defined below, different determine unless being provided in claims or elsewhere in this specification
Justice, otherwise these definition will be applicable in.
Regardless of whether explicitly pointing out, assume that all numerical value is modified by term " about " herein.Term " about " is logical
Referring to those skilled in the art will be considered that the digital model for being equal to cited value (for example, function having the same or result)
It encloses.In many cases, term " about " may include the numerical value being rounded to closest to effective digital.
The numberical range as disclosed in endpoint include in the range all numerical value (for example, 1 to 5 include 1,1.5,2,
2.75,3,3.80,4 and 5).
As used in this specification and in the appended claims, singular indefinite article " one " and definite article "the"
Including plural, unless being clearly dictated otherwise in text.As used in this specification and in the appended claims,
Using in meaning, term "or" generally includes "and/or", unless clearly dictating otherwise in text.
It should be noted that referring to that " embodiment ", " some embodiments ", " other embodiments " etc. show institute in the present specification
The embodiment of description may include one or more specific features, structure and/or characteristic.However, this narration is not meant to
All embodiments all include specific feature, structure and/or the characteristic.In addition, regardless of whether being expressly recited, with one embodiment
When combining the specific feature of description, structure and/or characteristic, it should be appreciated that this feature, structure and/or characteristic are equally applicable to
In other embodiments, unless expressly stated to the contrary on the contrary.
Following specific embodiments should be read with reference to the drawings, wherein in different figures, identical appended drawing reference table
Show identical element.Attached drawing is not necessarily to scale, and describes illustrative embodiment, it is no intended to limit the disclosure.
Fig. 1 shows demonstration Implantable medical device 10.Implantable medical device 10 can be configured to be located at body cavity in
For various medical applications.For example, in some cases, Implantable medical device 10 can be used to treat hemadostewnosis, it is used to
Maintain vascular, urinary tract, bile duct, tracheal bronchus, oesophagus or fluid openings or access in kidney road, or will such as artificial valve or
The device of filter is positioned in body cavity.In some cases, Implantable medical device 10 can be prosthetic implant, bracket
Graft or bracket (for example, vascular stent, trachea bracket, bronchial stent, Esophageal Stent etc.), aortic valve, filter
Deng.While shown as bracket, but Implantable medical device 10 can be and be drawn with endoscope, subcutaneous, percutaneous or modus operandi
Enter to be positioned in organ, tissue or lumen (heart, artery, vein, urethra, esophagus, trachea-bronchial epithelial cell, bile duct etc.)
A variety of devices in any one.
In some cases, it can be possible to it is expected to remove Implantable medical device 10 from body cavity.Some implantable brackets
Can have the open reticular structure or braided fabric for being amenable to tissue ingrowth.When tissue ingrowth occurs, branch is removed
Frame may be a kind of challenge.In order to reduce tissue ingrowth, covering or casing can be set on bracket.It is effectively reducing
While tissue ingrowth, the presence of casing allows bracket relative to implantation target migration.
As needed, Implantable medical device 10 is designed to be able to effectively remove ground, and has anti-migration characteristic.Example
Such as, Implantable medical device 10 can have the first section 12 and the second section 14.First section 12 and the second section 14 combine
It is used as expandable tubular frame together, which has open end and define the lumen across it.First
Section 12 can be described as not covering section, tissue ingrowth promotion section, anti-migration section etc..In other words, the first section 12
It can help to that Implantable medical device 10 is kept to be implanted in target site securely.In some cases, the first section 12 can
It is formed by crocheted line or silk thread, therefore can be described as crocheted section.It is inwardly raw that second section 14 can be described as covering section, tissue
It is long to resist section, removable section etc..In some cases, the second section 14 can be by multiple braidings or the line or silk that are interweaved
Line is formed, therefore can be described as braiding section.Jointly (collectively), section 12/14 are cooperated to cure to implantable
It treats device 10 and a variety of desired characteristics is provided.
First section 12 can be made of line 16.Line 16 can be round or noncircular cross section solid component, or can be with
It is tubulose (for example, there is round or noncircular cross section outer surface and/or circle or noncircular cross section inner surface).At least one
In a little situations, line 16 is configured to crocheted, usual columnar matrix (matrix), is fitting upon activation, can be from the first configuration
(for example, column) is disassembled to second and dismantles configuration (for example, configuring at substantially " straight line ").In at least some cases, first
Section 12 can be made of solid wire 16.This can simplify the dismantling of line 16.In order to help line 16 from first configuration conversion to dismantle configuration,
Release component or tab (tab) 18 may be disposed at the end regions of line 16.Release tab 18 can be line 16 and relatively easily hold
The part held and pulled is to disassemble line 16.
Second section 14 may include braided fabric or mesh 20.The lid component 22 can be arranged along braided fabric 20.The lid component 22 can
It is designed to reduce tissue ingrowth.Therefore, The lid component 22 allows the second section 14 in reasonable time point more easily
It is removed from implant site.The lid component 22 can be made of suitable material.For example, The lid component 22 may include silicone, polytetrafluoroethylene (PTFE),
Polyurethane etc. or other materials (including disclosed herein those).In some cases, The lid component 22 is along braided fabric 20
Outer surface setting.In other cases, The lid component 22 can be arranged along both the inner surface and the outer surface of braided fabric 20.In these feelings
In some and other situations in condition, The lid component 22 can encase braided fabric 20 or braided fabric 20 is embedded in it in other ways
In.It may include thermal, molding, coating, dip-coating, extrusion etc. that The lid component 22, which is attached to braided fabric 20,.These are demonstration example.
In addition, the second section 14 may also include removing components 24.Removing components 24 can be arranged along the second section 14 and can
For partly collapsing and/or helping to remove the second section 14 in other ways.In some cases, removing components 24 can be taken
The form of the suture provided around end regions of the braided fabric 20 adjacent to the first section 12.Removing components 24 can be along braided fabric
20 outer surface setting, the inner surface along braided fabric 20 is arranged, or can interweave with braided fabric 20.But removing components 24 it is usual this
Sample design, so that drawing (for example, proximally pulling) removing components 24 can apply radially-inwardly to the end regions of braided fabric 20
Power, so that braided fabric 20 be made effectively to convert the structure to more taper or collapse part, this can more easily remove implantable
Formula medical device 10 (for example, second section 14).
Section 12/14 is releasedly to each other.For example, in the first section 12 adjacent to the end of the second section 14, first
Section 12 (for example, line 16) may include the ring portion for extending through the opening in braided fabric 20.In this way, 12 system of the first section is to second
Section 14.When drag wire 16 is to the first section 12 of dismantling, the ring portion in line 16 can be pulled through braided fabric 20 so that the
One section 12 is detached from from the second section 14.Although ring connection is shown, it is also contemplated that other connection types.For example, first
Section 12 or part thereof may include biodegradable material, and the design of material is at dissolution after a predetermined amount of time or biology
It absorbs.When it happens, the first section 12 is effectively discharged from the second section 14.In other cases, for example, the first section
12 are bound to the second section 14 adhesively.
One or both in section 12,14 may be designed to configure in the first or " unexpanded " configuration and second or " expansion "
Between convert.In at least some cases, section 12, the one or both in 14 is by shape-memory material (for example, such as NiTi
The Nitinol of promise) it is made, unexpanded configuration can be constrained in delivery process, such as in delivering sheath, and not about
Expansion is self-expanded to (when being such as unfolded from delivering sheath and/or when being exposed under predetermined temperature in order to expand) when beam
Configuration.In other cases, section 12, the one or both in 14 may be designed to (all by suitable expansion or device
Such as, for example, sacculus) energetically expand.The exact material combination of section 12,14 can be varied as desired, and may include herein
Disclosed in material.
Fig. 2 shows the first sections 12.In this embodiment, the first section 12 can by by 16 looper of line or " crocheted " at
Desired structure is formed.The crocheted structure of line 16 can take the form of a succession of loosely related ring, and ring is to allow line 16 in column
The mode of its globality is maintained to be connected with each other when shape structure；Also allow simultaneously for example, by simply proximally drawing discharges tab
18 (and/or ends of line 16 itself) are relatively easily disassembled.In other words, the ring structure of crocheted line 16 allows line 16 to be pulled
(for example, by holding and pulling release tab 18) and dismantling.In addition, the ring frame of crocheted line 16 can also define a series of open
Mouthful, opening permission engages the opening along the tissue that 12 surface of the first section is arranged and grows in the opening.This allows the
One section 12 is mutually fixed in a manner of reducing Implantable medical device 10 in the ability of the intracavitary migration of objective body with surrounding tissue.
In some embodiments, the first section 12 may include additional structure feature, and the additional structural features are further
Help reduces Implantable medical device 10 in the intracavitary migration of objective body.For example, line 16 may include roughened surface, the roughening
Surface can frictionally engage body cavity surface.In some cases, line 16 can define a series of protruding portion or " tooth ", the protruding portion
Or " tooth " can engage tissue further to prevent Implantable medical device 10 from migrating in body cavity.Additional embodiment can wrap
Include other structure features.
Release tab 18 is also shown in Fig. 2.In at least some cases, release tab 18 online 16 end can be taken to increase,
Can gripping area form.The precise forms for discharging tab 18 are alterable.For example, release tab 18 can be tab, ring, increase portion
Section, planar section, polymer or drop of adhesive etc..
Fig. 3 shows the Implantable medical device 10 being implanted into along body cavity 26.As disclosed herein, implantable medical
When device 10 is implanted into along body cavity 26, tissue ingrowth can occur along the first section 12, this can reduce Implantable medical device
10 migrate in body cavity 26.In some embodiments, Implantable medical device 10 can be removed from body cavity 26.
Fig. 4 shows a part for removing the process of Implantable medical device 10.For example, the first removing components 28 can be used to
Hold release tab 18.First removing components 28 can proximally bounce back until the first section 12 is disassembled and discharged from the second section 14
It opens, as shown in Figure 5.To do so, the first section 12 is disassembled, separates with the second section 14, and can remove from body cavity 26.Example
Such as, the line 16 of the first section 12 can be pulled into " straight line " structure of the dismantling discharged from the second section 14.Along the first section
In the case that 12 occur tissue ingrowth, the dismantling of line 16 can permit what line 16 was pulled from ingrown tissue
Mode (for example, in a manner of being similar to and pull suture from wound closure) occurs.
Second removing components 30 can be used to remove the second section 14 from body cavity 26, as shown in Figure 6.For example, second removes
Component 30 may include the gripping section or hook 32 for engaging removing components 24.Second removing components 30 (it schematically shows) can have
There is the various forms for being adapted to engage with removing components 24.Removing the second section 14 may include simply from body cavity 26 (final, patient)
Pull the second section 14.Alternatively, tubulose removal or again acquisition equipment can be used.For example, the second section 14 can bounce back to tubulose shifting
Except then being removed from body cavity 26 in device.
It can be used for the various assemblies of Implantable medical device 10 (and/or other devices disclosed herein) and be disclosed herein
The materials of various tubular elements may include material those of related to medical device.Implantable medical device 10 and/or its
Component can be by metal, metal alloy, and polymer (disclosed below some demonstration examples), metal-polymer composites, ceramics,
And combinations thereof etc. or other suitable materials.Some demonstration examples of suitable polymer may include polytetrafluoroethylene (PTFE) (PTFE),
Ethylene-tetrafluoroethylene (ETFE), fluorinated ethylene propylene (FEP), polyoxyethylene methylene (POM, for example, what E.I.Du Pont Company sold), polyether block ester, polyurethane (for example, polyurethane 85A), polypropylene (PP), polyvinyl chloride (PVC), polyether ester
(for example, what DSM Engineered Plastics sold), ether or ester group copolymer are (for example, butylene/poly- (alkylene
Ether) phthalic acid ester and/or such as E.I.Du Pont Company sellPolyester elastomer), polyamide is (for example, Baeyer
What company soldOr the sale of Ai Erfu atropic company), elastomer polyamide, block polyamides
Amine/ether, polyether block amide (PEBA, such as withThe product sold for trade (brand) name), ethylene-vinyl acetate c
Object (EVA), silicone resin, polyethylene (PE), Marlex high density polyethylene (HDPE), Marlex low density polyethylene (LDPE) are linear low close
Degree polyethylene (for example,), polyester, polybutylene terephthalate (PBT) (PBT), polyethylene terephthalate
(PET), polypropylene terephthalate (polytrimethyleneterephthalate), polyethylene naphthalate
(PEN), polyether-ether-ketone (PEEK), polyimides (PI), polyetherimide (PEI), polyphenylene sulfide (PPS), polyphenylene oxide (PPO),
Poly(p-phenylene terephthalamide) (for example,), polysulfones, nylon, Nylon-12 (such as EMS AmericanGrilon
What company sold), perfluor (propyl vinyl ether) (PFA), ethylene vinyl alcohol, polyolefin, polystyrene,
Epoxy resin, polyvinylidene chloride (PVdC), poly- (styrene-b-isobutylene-b-styrene) is (for example, SIBS and/or SIBS
50A), polycarbonate, ionomer, bioavailable polymer, the mixture of other suitable materials or previous materials, combination
Object, copolymer, polymer/metal composition etc..In some embodiments, sheath can be mixed with liquid crystal polymer (LCP).
For example, mixture may include the LCP for being up to about 6%.
Some demonstration examples of suitable metal and metal alloy include such as 304V, 304L and 316LV stainless steel it is stainless
Steel；Mild steel；The Ni-Ti alloy of such as linear elasticity and/or superelastic Nitinol；Such as Ni-Cr-Mo alloy is (for example, such as625 UNS:N06625, such asUNS:N06022, such asUNS:N10276, otherAlloy etc.) other nickel alloys, nickel-copper alloy
(for example, such as400,400,400 equal UNS:N04400), nickel-cobalt-chromium-
Molybdenum alloy is (for example, such asDeng UNS:R30035), nickel-molybdenum alloy is (for example, such asALLOYUNS:N10665), other nickel-chromium alloys, other nickel-molybdenum alloys, other nickel-cobalt alloys, other nickel-ferro alloys,
His nickel-copper alloy, other nickel-tungstens or tungsten alloy etc.；Cobalt-chromium alloy；Cobalt-chromium-molybdenum alloy is (for example, such asDeng UNS:R30003)；Platinum is enriched with stainless steel；Titanium；And combinations thereof etc.；Or any other conjunction
Suitable material.
As mentioned in this article, in the family of commercially available Ni-Ti or nitinol, there are referred to as " linear elasticity " or " non-superlastic
Property " type, although its in terms of chemical property be similar to common shape memory and super-elasticity type, can show solely
Special and beneficial mechanical performance.The difference of linear elasticity and/or non-superelastic Nitinol and superelastic Nitinol can be, linear elasticity
And/or non-superelastic Nitinol does not have the " super-elasticity level ground (superelastic of essence in stress/strain curves
Plateau) " or " mark region (flag region) ", and superelastic Nitinol then has.On the contrary, in linear elasticity and/or non-
In superelastic Nitinol, as recoverable strain increases, stress is or slightly linear with substantial linear, but need not be fairly linear
Relationship persistently increases until plastic deformation starts or at least than super-elasticity level ground and/or logo area shown in superelastic Nitinol
The more linear relationship in domain.In this way, for purposes of this disclosure, linear elasticity and/or non-superelastic Nitinol are alternatively referred to as " greatly
Cause " linear elasticity and/or non-superelastic Nitinol.
In some cases, the difference of linear elasticity and/or non-superelastic Nitinol and superelastic Nitinol can also be, line
Elastic and/or non-superelastic Nitinol can keep it is substantially resilient while bear up to the strain of about 2-5% (for example,
Before plastic deformation), and superelastic Nitinol can bear up to about 8% strain before plastic deformation.Both materials
It can be differentiated, other linear elasticities with other linear elastic materials (it can also be differentiated according to component) of such as stainless steel
Material can only bear about 0.2 to 0.44% strain before plastic deformation.
In some embodiments, linear elasticity and/or non-superelastic nickel-titanium alloy are that do not have any martensitic traoformation/Austria
The alloy of family name's body phase transformation, phase transformation can be by differential scanning calorimeters (DSC) and dynamic metal heat analysis (DMTA) in very big temperature
It is analyzed in degree range and detects to obtain.For example, in some embodiments, arriving about 120 at about -60 degrees Celsius (DEG C)
Linear elasticity and/or non-super is not measured by differential scanning calorimeter (DSC) and dynamic metal heat analysis (DMTA) in the range of DEG C
Martensitic traoformation/austenite phase transformation of elastic Ni-Ti alloy.Therefore, within the scope of this very broad temperature, this material
Mechanical bend performance will not usually be affected by temperature.In some embodiments, linear elasticity and/or non-superelastic nickel-
Titanium alloy mechanical bend performance at ambient or room temperature and mechanical performance under body temperature are essentially identical, for example, not
Show super-elasticity level ground and/or mark region.In other words, within the scope of broad temperature, linear elasticity and/or non-superelastic nickel-
Titanium alloy keeps its linear elasticity and/or non-super elastic characteristics and/or performance.
In some embodiments, the weight percent of nickel can be about 50 in linear elasticity and/or non-superelastic nickel-titanium alloy
To in the range of about 60, rest part is essentially titanium.In some embodiments, the weight percent of nickel is about 54 to greatly
In the range of about 57.Suitable Ni-Ti alloy another example is the Furukawa Techno of Kanagawa, Japan
The FHP-NT alloy of Material Co. sale.NiTi is disclosed in U.S. Patent No. No. 5,238,004 and No. 6,508,803
Some examples of alloy are incorporated into this by reference.Other suitable materials may include ULTANIUMTMIt (can be from Neo-
The purchase of Metrics company) and GUM METALTM(can be bought from Toyota Company).In some other embodiments, super-elasticity
Alloy (such as superelastic Nitinol) can be used to realize desired performance.
In at least some embodiments, some parts of device 10 or all can also be doped with, material be, or including impermeable
The material of ray.Radiopaque material is interpreted as in medical procedure can be on fluorescope screen or another imaging
Technically generate the material of relatively bright image.This relatively bright image can the user of aid-device 10 determine its position
It sets.Some examples of radiopaque material can include but is not limited to gold, platinum, palladium, tantalum, and tungsten alloy is filled out equipped with radiopaque
The polymer material etc. of material.In addition, other radiopaque labels bands and/or coil also be included in the design of device 10 with
Realize identical result.
In some embodiments, device 10 a degree of magnetic resonance imaging (MRI) compatibility is given.For example, device 10
Or some parts can be by not making image fault substantially and not generating the material system in substantive artifact (for example, gap in image)
At.For example, certain ferromagnetic materials may be not suitable for, because they can generate artifact in MRI image.Device 10 or some portions
Dividing can also be made of the material that MRI machine can be imaged.The some materials for showing these characteristics include, such as tungsten, cobalt-chromium-
Molybdenum alloy is (for example, such asDeng UNS:R30003), nickel-cobalt-chromium-molybdenum alloy is (for example, such asDeng UNS:R30035), Nitinol etc. and other materials.
It should be understood that the disclosure is merely illustrative in many aspects.It, can be thin without departing from disclosure range
Section makes variation more particularly to shape, size and procedure aspect.In suitable degree, this may include showing one
Any feature in model embodiment is in other embodiments.
Claims (12)
1. a kind of Implantable medical device, comprising:
Bracket, the bracket have lumen, covering part and the unmasked portion for extending through it；
Along the The lid component of covering part setting, the The lid component is designed to that limitation tissue is inwardly given birth to along the covering part
It is long；
Wherein the unmasked portion of the bracket is configured to allow for tissue to grow into it, to reduce moving for the bracket
It moves；
Wherein the unmasked portion is configured to configure to disassemble to second from the first column to dismantle configuration.
2. Implantable medical device according to claim 1, wherein the unmasked portion of the bracket is by single
Line is made.
3. Implantable medical device according to claim 2, wherein solid wire formation is matched with first column
A succession of loosely related ring interconnected is set, can be disassembled and proximally pulling the solid wire.
4. Implantable medical device according to claim 2, wherein the end of the solid wire includes release tab.
5. Implantable medical device according to claim 2, wherein the solid wire of the unmasked portion extends
Pass through the ring of the covering part.
6. Implantable medical device according to claim 2, wherein the unmasked portion of the bracket is crocheted
Part.
7. according to claim 1 to any Implantable medical device in 6, wherein the covering part of the bracket
It is formed by multiple litzendraht wires.
8. according to claim 1 to any Implantable medical device in 6, wherein the covering part is releasedly attached
It is connected to the unmasked portion.
9. according to claim 1 to any Implantable medical device in 6, wherein the covering part includes for helping
Help the removing components that the covering part is removed from implant site.
10. Implantable medical device according to claim 9, wherein the removing components are configured to the covering part
The end regions divided apply radially inward power so that the end regions are moved to the configuration of collapse part.
11. Implantable medical device according to claim 9 or 10, wherein the removing components are included in the bracket
The covering part provided around suture.
12. Implantable medical device according to claim 1 or 2, wherein the unmasked portion includes that biological can drop
The material of solution.
Applications Claiming Priority (3)
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|---|---|---|---|
| US201562104356P | 2015-01-16 | 2015-01-16 | |
| US62/104,356 | 2015-01-16 | ||
| CN201680010573.XA CN107405193B (en) | 2015-01-16 | 2016-01-14 | The Implantable medical device that transfer ability reduces |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680010573.XA Division CN107405193B (en) | 2015-01-16 | 2016-01-14 | The Implantable medical device that transfer ability reduces |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110037827A true CN110037827A (en) | 2019-07-23 |
| CN110037827B CN110037827B (en) | 2021-11-30 |
Family
ID=55273548
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910271217.9A Active CN110037827B (en) | 2015-01-16 | 2016-01-14 | Implantable medical device with reduced migration capability |
| CN201680010573.XA Active CN107405193B (en) | 2015-01-16 | 2016-01-14 | The Implantable medical device that transfer ability reduces |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680010573.XA Active CN107405193B (en) | 2015-01-16 | 2016-01-14 | The Implantable medical device that transfer ability reduces |
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| Country | Link |
|---|---|
| US (3) | US10524939B2 (en) |
| EP (2) | EP3244829B1 (en) |
| JP (1) | JP6423541B2 (en) |
| KR (1) | KR102047167B1 (en) |
| CN (2) | CN110037827B (en) |
| WO (1) | WO2016115403A1 (en) |
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| CN109528352A (en) * | 2019-01-15 | 2019-03-29 | 哈尔滨工业大学 | A kind of shape-memory polymer carries medicine intestinal stent and preparation method thereof |
| WO2023104157A1 (en) * | 2021-12-10 | 2023-06-15 | 深圳市先健呼吸科技有限公司 | Airway stent |
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| US10426592B2 (en) | 2016-04-11 | 2019-10-01 | Boston Scientific Scimed, Inc. | Implantable medical device with reduced migration capabilities |
| US11026818B2 (en) | 2018-04-23 | 2021-06-08 | Boston Scientific Scimed, Inc. | Stent with selectively covered region |
| CA3102102C (en) * | 2018-06-04 | 2023-03-28 | Boston Scientific Scimed, Inc. | Removable stent |
| EP3597155A1 (en) * | 2018-07-17 | 2020-01-22 | Cook Medical Technologies LLC | Stent having a stent body and detachable anchor portion |
| US20220117718A1 (en) * | 2019-01-31 | 2022-04-21 | Becton, Dickinson And Company | Mixed-Frame Intraluminal Prosthesis And Methods Thereof |
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| CN109528352B (en) * | 2019-01-15 | 2022-02-22 | 哈尔滨工业大学 | Shape memory polymer drug-loaded intestinal stent and preparation method thereof |
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Also Published As
| Publication number | Publication date |
|---|---|
| US20220008232A1 (en) | 2022-01-13 |
| EP3569192A1 (en) | 2019-11-20 |
| US11147695B2 (en) | 2021-10-19 |
| US10524939B2 (en) | 2020-01-07 |
| CN107405193A (en) | 2017-11-28 |
| CN107405193B (en) | 2019-04-30 |
| EP3569192B1 (en) | 2023-04-12 |
| KR20170104581A (en) | 2017-09-15 |
| KR102047167B1 (en) | 2019-11-20 |
| CN110037827B (en) | 2021-11-30 |
| EP3244829A1 (en) | 2017-11-22 |
| US20160206449A1 (en) | 2016-07-21 |
| WO2016115403A1 (en) | 2016-07-21 |
| US20200121481A1 (en) | 2020-04-23 |
| JP6423541B2 (en) | 2018-11-14 |
| JP2018505723A (en) | 2018-03-01 |
| EP3244829B1 (en) | 2020-12-30 |
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