CN109999172A - A kind of Chinese medicine composition and preparation method thereof for treating ringworm of the body - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating ringworm of the body Download PDFInfo
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- CN109999172A CN109999172A CN201910402789.6A CN201910402789A CN109999172A CN 109999172 A CN109999172 A CN 109999172A CN 201910402789 A CN201910402789 A CN 201910402789A CN 109999172 A CN109999172 A CN 109999172A
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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Abstract
The present invention relates to a kind of Chinese medicine compositions and preparation method thereof for treating ringworm of the body, belong to the field of Chinese medicines, including material composition and its mass fraction be respectively as follows: 5-15 parts of rhizoma zingiberis, 10-20 parts of Radix Polygalae, 5-15 parts of ramulus cinnamomi, 10-40 parts of rhizoma anemarrhenae, 15-25 parts of dandelion, 10-20 parts of Radix Rehmanniae, 15-25 parts of flos caryophylli, 5-15 parts of Radix Glycyrrhizae, 25-35 parts of radix scutellariae and 5-15 parts of Schisandra chinensis.Cost is relatively low for the Chinese medicine composition, and preparation method is simple, and therapeutic effect is good, preventing from scar, is not easy repeatedly, without any side effects, has biggish market prospects.
Description
Technical field
The invention belongs to the field of Chinese medicines, and in particular, to a kind of Chinese medicine composition and preparation method thereof for treating ringworm of the body.
Background technique
Ringworm of the body is colonized on the glabrous skin of human body by pathogenic fungus (except hand, foot, hair, deck and genitocrural
Skin in addition) caused by Dermal skin infection.After pathogenic fungus invades the cuticula of human body surface, it can cause very
The damage such as erythema, papule, blister, followed by furfur occur for light inflammatory reaction, often annular in shape, therefore are commonly called as tinea circinata or tinea glabrosa.It is all kinds of
The treatment of ringworm of the body, generally based on external drug.Salicylate compound tincture, whitfield ointment, compound resorcinol paint,
1% econazole frost or clotrimazole cream, 20% corter pseudolaricis tincture, 2% Miconazole frost, bifonazole, ketoconazole, Terbinafine etc..
Ringworm of the body is a kind of skin disease relatively common during we live, first it is envisioned that again ugly when mentioning this disease
Itch again, people is allowed extremely to feel bad.This cause of disease itch is scratched, and will cause skin injury, can cause secondary infection.Ringworm of the body is stupider
Gu treating more intractable, easy recurrence under the influence of uncertainty, also because itch is hard to bear, it is easier to spread, seriously affect
The normal life of patient, and currently, have no highly effective treatment method.
Summary of the invention
In order to solve deficiency in the prior art, the purpose of the present invention is to provide a kind of Chinese traditional medicine compositions for treating ringworm of the body
Object, purpose two are to provide the preparation method of above-mentioned Chinese medicine composition.Cost is relatively low for the Chinese medicine composition, preparation method letter
Single, therapeutic effect is good, is not easy repeatedly, without any side effects.
To achieve the goals above, the present invention use the specific scheme is that
A kind of Chinese medicine composition for treating ringworm of the body, including material composition and its mass fraction be respectively as follows: 5-15 parts of rhizoma zingiberis, Radix Polygalae
10-20 parts, 5-15 parts of ramulus cinnamomi, 10-40 parts of rhizoma anemarrhenae, 15-25 parts of dandelion, 10-20 parts of Radix Rehmanniae, 15-25 parts of flos caryophylli, Radix Glycyrrhizae 5-
15 parts, 25-35 parts of radix scutellariae and 5-15 parts of Schisandra chinensis.
Advanced optimized as to above scheme, it is described treatment ringworm of the body Chinese medicine composition, including material composition and
Its mass fraction is respectively as follows: 10 parts of rhizoma zingiberis, 15 parts of Radix Polygalae, 10 parts of ramulus cinnamomi, 20 parts of rhizoma anemarrhenae, 20 parts of dandelion, 15 parts of Radix Rehmanniae, public fourth
20 parts fragrant, 10 parts of Radix Glycyrrhizae, 30 parts of radix scutellariae and 10 parts of Schisandra chinensis.
The present invention also provides the preparation methods of the Chinese medicine composition of above-mentioned treatment ringworm of the body, comprising the following steps:
Step 1: weighing rhizoma zingiberis, Radix Polygalae, ramulus cinnamomi, rhizoma anemarrhenae, dandelion, Radix Rehmanniae, flos caryophylli, Radix Glycyrrhizae, Huang respectively according to mass fraction
Ten kinds of raw materials of a kind of reed mentioned in ancient books and Schisandra chinensis, it is spare；
Step 2: weighed ten kinds of raw materials of step 1 are mixed, mixture is obtained；Add water 4000-6000mL into every kg mixture,
30-40min is impregnated, mild fire is heated to boiling, then uses intense fire instead and continue to terminate after heating 10-15min, filters, obtains filtrate I and filter
Slag I；
Step 3: continuing to add water 2000-3000 mL into filter residue I obtained by step 2, intense fire is heated to boiling, and continues to heat 8-
10min, filtering, obtains filtrate II；
Step 4: filtrate II obtained by filtrate I obtained by step 2 and step 3 is uniformly mixed, finished product is obtained.
Each taste herbal nature feature in above-mentioned raw materials:
Rhizoma zingiberis: acrid flavour, property heat, returns spleen, stomach, the heart, lung channel；Warming spleen and stomach for dispelling cold, recover Yang and smooth venation, eliminating dampness dissolving phlegm, warming lung and resolving fluid.
Radix Polygalae: bitter, pungent, warm, return heart, kidney, lung channel；Tranquilize the mind and promote the intelligence, relieve stagnation control palpitation with fear, amnesia, and nocturnal emission is had a sleepless night, cough
More phlegm, ulcer sore swells.
Ramulus cinnamomi: taste acrid, sweet, warm enter lung, the heart, bladder meridian；Sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi.
Rhizoma anemarrhenae: it is bitter, sweet, it trembles with fear；Return lung, stomach, kidney channel；Clearing heat-fire, nourishing Yin and moistening dryness.
Dandelion: it is bitter, sweet, it trembles with fear；Return liver, stomach meridian；It is clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia.
Radix Rehmanniae: it is sweet, it trembles with fear.Return heart, liver, kidney channel；Clearing heat and cooling blood, yin-nourishing are promoted the production of body fluid.For the deep red polydipsia of pyreticosis tongue, yin asthenia generating intrinsic heat,
Hectic fever due to yin labor heat, Heat Diabetes are spitted blood, bleeding from five sense organs or subcutaneous tissue, spot dermexanthesis.
Flos caryophylli: property is pungent, taste temperature.Enter lung, spleen, stomach, kidney four to pass through.Effect: middle benefit gas, warm kidney, drop are inverse.The major functions: controlling hiccup, vomitting
It spits, gastric disorder causing nausea, dysentery, trusted subordinate's crymodynia, Xuan addiction, hernia, ringworm.
Radix Glycyrrhizae: sweet, flat, return heart, lung, spleen, stomach meridian；It invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain reconciles all
Medicine.
Radix scutellariae: it is bitter, it trembles with fear；Return lung, gallbladder, spleen, stomach, large intestine, small intestinl channel；Primary efficacy: heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis,
Miscarriage prevention.
Schisandra chinensis: warm, sour, sweet；Return lung, the heart, kidney channel；With astringency inducing, the effect of Mi Gu granule, kidney calming.
The utility model has the advantages that
1, for Chinese medicine composition of the present invention using rhizoma anemarrhenae, Radix Rehmanniae and radix scutellariae as monarch drug in a prescription, Radix Polygalae, ramulus cinnamomi and dandelion are ministerial drug, are done
Ginger and flos caryophylli are adjutant, and Radix Glycyrrhizae and Schisandra chinensis are to make medicine, monarch coordinative role, effective molecule by the defeated cloth of channels and collaterals,
The adjustings of internal organs reaches lesion, adjusts whole body function, promotes blood circulation, and accelerates metabolite excretion, promote inflammatory induced pain because
Son absorbs, and improves body defenses and immunocompetence, has the function of to promotion functions recovery positive.
2, Chinese medicine composition of the present invention has abandoned the way that conventional therapy uses external medication, passes through Chinese medicine tune
With suited the remedy to the case using cold drug, in conjunction with specific basal part of the ear acupoint therapy, go deep into blood, solve blood circulation, from the inside to surface
It repairs, eradicates superficial part lesion, so that skin restores normal, and do not stay any scar, it is without any side effects.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described.
Embodiment 1
A kind of Chinese medicine composition for treating ringworm of the body, including material composition and its mass fraction be respectively as follows:
10 parts of rhizoma zingiberis, 15 parts of Radix Polygalae, 10 parts of ramulus cinnamomi, 20 parts of rhizoma anemarrhenae, 20 parts of dandelion, 15 parts of Radix Rehmanniae, 20 parts of flos caryophylli, Radix Glycyrrhizae 10
Part, 30 parts of radix scutellariae and 10 parts of Schisandra chinensis.
Above-mentioned Chinese medicine composition follows the steps below preparation, the specific steps are as follows:
Step 1: weighing rhizoma zingiberis, Radix Polygalae, ramulus cinnamomi, rhizoma anemarrhenae, dandelion, Radix Rehmanniae, flos caryophylli, sweet respectively according to above-mentioned mass fraction
Ten kinds of grass, radix scutellariae and Schisandra chinensis raw materials, it is spare；
Step 2: weighed ten kinds of raw materials of step 1 are mixed, mixture is obtained；Add water 4000mL into every kg mixture, impregnates
30min, mild fire are heated to boiling, then use intense fire instead and continue to terminate after heating 10min, filter, obtain filtrate I and filter residue I；
Step 3: continuing to add 3000 mL of water into filter residue I obtained by step 2, intense fire is heated to boiling, and continues to heat 10 min,
Filtering, obtains filtrate II；
Step 4: filtrate II obtained by filtrate I obtained by step 2 and step 3 is uniformly mixed, finished product is obtained.
Embodiment 2
A kind of Chinese medicine composition for treating ringworm of the body, including material composition and its mass fraction be respectively as follows:
5 parts of rhizoma zingiberis, 10 parts of Radix Polygalae, 5 parts of ramulus cinnamomi, 10 parts of rhizoma anemarrhenae, 15 parts of dandelion, 10 parts of Radix Rehmanniae, 15 parts of flos caryophylli, 5 parts of Radix Glycyrrhizae,
25 parts and 5 parts of Schisandra chinensis of radix scutellariae.
Above-mentioned Chinese medicine composition follows the steps below preparation, the specific steps are as follows:
Step 1: weighing rhizoma zingiberis, Radix Polygalae, ramulus cinnamomi, rhizoma anemarrhenae, dandelion, Radix Rehmanniae, flos caryophylli, Radix Glycyrrhizae, Huang respectively according to mass fraction
Ten kinds of raw materials of a kind of reed mentioned in ancient books and Schisandra chinensis, it is spare；
Step 2: weighed ten kinds of raw materials of step 1 are mixed, mixture is obtained；Add water 5000mL into every kg mixture, impregnates
35min, mild fire are heated to boiling, then use intense fire instead and continue to terminate after heating 15min, filter, obtain filtrate I and filter residue I；
Step 3: continuing to add water 2500mL into filter residue I obtained by step 2, intense fire is heated to boiling, and continues to heat 8min, mistake
Filter, obtains filtrate II；
Step 4: filtrate II obtained by filtrate I obtained by step 2 and step 3 is uniformly mixed, finished product is obtained.
Embodiment 3
A kind of Chinese medicine composition for treating ringworm of the body, including material composition and its mass fraction be respectively as follows:
15 parts of rhizoma zingiberis, 20 parts of Radix Polygalae, 15 parts of ramulus cinnamomi, 40 parts of rhizoma anemarrhenae, 25 parts of dandelion, 20 parts of Radix Rehmanniae, 25 parts of flos caryophylli, Radix Glycyrrhizae 15
Part, 35 parts of radix scutellariae and 15 parts of Schisandra chinensis.
Above-mentioned Chinese medicine composition follows the steps below preparation, the specific steps are as follows:
Step 1: weighing rhizoma zingiberis, Radix Polygalae, ramulus cinnamomi, rhizoma anemarrhenae, dandelion, Radix Rehmanniae, flos caryophylli, Radix Glycyrrhizae, Huang respectively according to mass fraction
Ten kinds of raw materials of a kind of reed mentioned in ancient books and Schisandra chinensis, it is spare；
Step 2: weighed ten kinds of raw materials of step 1 are mixed, mixture is obtained；Add water 6000mL into every kg mixture, impregnates
40min, mild fire are heated to boiling, then use intense fire instead and continue to terminate after heating 15min, filter, obtain filtrate I and filter residue I；
Step 3: continuing to add water 2000mL into filter residue I obtained by step 2, intense fire is heated to boiling, and continues to heat 10min, mistake
Filter, obtains filtrate II；
Step 4: filtrate II obtained by filtrate I obtained by step 2 and step 3 is uniformly mixed, finished product is obtained.
After Chinese medicine composition of the present invention prepares, divides 3 doses, three times a day, continuously take 9 days as one therapeutic course.It took
Basal part of the ear acupuncture point is pricked in cooperation in journey, and deep promotes blood circulation.
The present invention, which can according to need, is made other different dosage forms such as lotion.
Hygienic chemistry index to the Chinese medicine composition of above-described embodiment 1-3 preparation includes that mercury, arsenic, lead, methanol etc. accord with
Close marked price standard；Microbiological indicator includes that total number of bacteria, Escherichia coli, Pseudomonas aeruginosa and staphylococcus aureus etc. also meet
National standard.In short, Chinese medicine composition of the present invention meets national quality and safe and healthy standard through detecting.
The Chinese medicine composition of embodiment 1-3 preparation is further detected.
One, clinical data
1, general information
(1) illness feature: typical predilection site betides the positions such as face, neck, trunk and four limbs.Initial is syringe needle to mung bean size
Papule, blister or papulo-vesicle, develop outward from center, most important is exactly itch, have a more clear erythema in boundary, one
Especially important feature is exactly that edge is swelled at dike shape, and central part may occur in which multilayer concentric circle sample damage.
(2) selected case: according to the above case inclusion criteria, 200 patients, age distribution 18-50 are selected immediately
In year, it is equally divided into 4 groups, every group of 50 people, men and women is fifty-fifty；Comparative example is to be smeared using salicylate compound tincture according to its specification.It controls
Therapeutic effect see the table below 1.
Efficacy determination: 1. fully recover: symptom disappears, and does not stay scar；2. effectively: the complications shape of various difference ringworm of the body patients
It substantially reduces；3. invalid: variation is little before and after treatment, or once improves, and restores again afterwards to the preceding symptom for the treatment of.It is counted after 1 year multiple
Hair rate.
Table 1: therapeutic effect contrast table
Compare for four groups it can be seen from upper table 1, treatment group (embodiment 1-3) is substantially better than control group (reference examples), there is conspicuousness
Difference (P < 0.05).Compared with commercially available external drug, the Chinese medicine composition of 1-3 of embodiment of the present invention preparation is cured efficient
Up to 96%, and recurrence rate is lower, while passing through the skin after observation healing, skin moisturizing degree, smoothness, skin line
Reason and elasticity tend to normal level, and not described have adverse reaction.Therefore, Chinese medicine composition of the present invention is not only in treatment body
It has a better effect in terms of tinea, meanwhile, smaller to skin irritatin, it is lower that scar leaves rate, to restoring skin elasticity, conditioning skin
Situation has positive effect, has preferable market prospects.
Typical case:
1, river, female, 28 years old, illness 3 years, symptom was mainly distributed on lower limb, and initial stage is the macula of several soya bean sizes, with
Gradually increase to first Gai great little afterwards, clear-cut margin, after be mutually fused into irregular large stretch of shape, and surrounding has new macula appearance,
Finally add up the positions such as buttocks, thigh, surface is alternately present with the chaff sample scales of skin that peel off easily removed on a small quantity, grey, brown, shape
Such as piebald.Occasionally there is slight scratchiness.Winter fash is reduced, but summer can recur again.After taking Chinese medicine composition of the present invention,
Basal part of the ear acupuncture point is pricked in cooperation, and course for the treatment of symptom mitigates, and three courses for the treatment of recoveries from illness, skin restores as before, but continue to take two months into
Row is consolidated, no relapse after 1 year.
2, Korea Spro, male, 50 years old, peasant；Main suit's right forearm annular erythema, warts one month；The patient is before one month, without bright
There is papule in aobvious inducement discovery right forearm, itches, a variety of external application hormone ointment of using by oneself, after improvement again repeatedly, and skin lesion is gradually expanded
Greatly, and there is pimple；After diagnosing, the visible about 6 × 8cm size annular erythema skin lesion of right forearm.Take Chinese medicine of the present invention
Basal part of the ear acupuncture point is pricked in composition, cooperation, and three courses for the treatment of are cured substantially, no relapse.
3, it is outstanding certain, male 37 years old, suffers from ringworm of the body 3 years, from the beginning of for erythema, maculopapule, small papule, papulo-vesicle, later ringworm of the body
Progression of the disease quickly, is fused into patch quickly, and with the itch differed in weight, serious ringworm of the body makes him that can not work finally.Zeng
Many hospitals have seen, and most of to the externally applied drug opened and some antimycotic medicines, very effective after having used, can be discontinued later fash
It just comes out again, root cannot be removed.Chinese medicine composition of the present invention is taken, basal part of the ear acupuncture point is pricked in cooperation, and a course for the treatment of itch is taken a favourable turn,
Two course for the treatment of skin lesions disappear, and three course for the treatment of skins are gradually good, continue to take after two months, and skin restores, and does not have scar, have no multiple
Hair.
It should be noted that embodiment described above is interpreted as illustrative, to be not intended to limit the present invention protection
Range, protection scope of the present invention are subject to claims.To those skilled in the art, without departing substantially from of the invention real
Under the premise of matter and range, some nonessential modifications and adaptations made to the present invention still fall within protection scope of the present invention.
Claims (3)
1. a kind of Chinese medicine composition for treating ringworm of the body, it is characterised in that: including material composition and its mass fraction be respectively as follows: it is dry
5-15 parts of ginger, 10-20 parts of Radix Polygalae, 5-15 parts of ramulus cinnamomi, 10-40 parts of rhizoma anemarrhenae, 15-25 parts of dandelion, 10-20 parts of Radix Rehmanniae, flos caryophylli
15-25 parts, 5-15 parts of Radix Glycyrrhizae, 25-35 parts of radix scutellariae and 5-15 parts of Schisandra chinensis.
2. a kind of Chinese medicine composition for treating ringworm of the body according to claim 1, it is characterised in that: including material composition and
Its mass fraction is respectively as follows: 10 parts of rhizoma zingiberis, 15 parts of Radix Polygalae, 10 parts of ramulus cinnamomi, 20 parts of rhizoma anemarrhenae, 20 parts of dandelion, 15 parts of Radix Rehmanniae, public fourth
20 parts fragrant, 10 parts of Radix Glycyrrhizae, 30 parts of radix scutellariae and 10 parts of Schisandra chinensis.
3. a kind of preparation method of Chinese medicine composition for treating ringworm of the body according to claim 1 or 2, it is characterised in that: packet
Include following steps:
Step 1: weighing rhizoma zingiberis, Radix Polygalae, ramulus cinnamomi, rhizoma anemarrhenae, dandelion, Radix Rehmanniae, flos caryophylli, Radix Glycyrrhizae, Huang respectively according to mass fraction
Ten kinds of raw materials of a kind of reed mentioned in ancient books and Schisandra chinensis, it is spare；
Step 2: weighed ten kinds of raw materials of step 1 are mixed, mixture is obtained；Add water 4000-6000mL into every kg mixture,
30-40min is impregnated, mild fire is heated to boiling, then uses intense fire instead and continue to terminate after heating 10-15min, filters, obtains filtrate I and filter
Slag I；
Step 3: continuing to add water 2000-3000 mL into filter residue I obtained by step 2, intense fire is heated to boiling, and continues to heat 8-
10min, filtering, obtains filtrate II；
Step 4: filtrate II obtained by filtrate I obtained by step 2 and step 3 is uniformly mixed, finished product is obtained.
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| CN102018780A (en) * | 2010-12-14 | 2011-04-20 | 确山龙源药业有限公司 | Skin bacteriostatic agent and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102018780A (en) * | 2010-12-14 | 2011-04-20 | 确山龙源药业有限公司 | Skin bacteriostatic agent and preparation method thereof |
Non-Patent Citations (3)
| Title |
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| FENGCTLD_947: "青岛去哪里看皮肤病比较好", 《BLOG.SINA.COM.CN/S/BLOG_A5B730620101A5YY.HTML》 * |
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