CN109998750A - A kind of self-constriction formula stent graft - Google Patents
A kind of self-constriction formula stent graft Download PDFInfo
- Publication number
- CN109998750A CN109998750A CN201910362245.1A CN201910362245A CN109998750A CN 109998750 A CN109998750 A CN 109998750A CN 201910362245 A CN201910362245 A CN 201910362245A CN 109998750 A CN109998750 A CN 109998750A
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- China
- Prior art keywords
- self
- stent graft
- rack body
- shaped end
- layer
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
Abstract
The invention discloses a kind of self-constriction formula stent grafts, including rack body, the rack body is formed by way of braiding, wherein, the rack body is in hollow cylinder-like structure under softened state, the braided wires end of the rack body is connected to form closed U-shaped end, and forms the first slanted angle between the U-shaped end and rack body central axis.Self-constriction formula stent graft provided by the invention is not only able to promote bracket end that can collapse from trend central axis, prevents the compression profile of closed type braided support from increasing, and the push power of braided support can also be effectively reduced simultaneously.
Description
Technical field
The present invention relates to a kind of stent graft more particularly to a kind of self-constriction formula stent grafts.
Background technique
Stent graft is the treatment common instrument of the diseases such as cardiovascular and cerebrovascular and the narrow, hemangioma of peripheral blood vessel.Clinically
Stent graft is usually to be placed into human vas lesion in conduit, seal wire and specially under the assistance of push rod for designing etc.
Position.The artery and vein vascular of lesion is easy to happen in human body, internal diameter minimum only has 2mm or so, in order to ensure bracket can be placed
It is as small as possible for the compression profile requirements of bracket itself into blood vessel, thus can be with when ensureing using thinner delivery conduit
Smoothly push and release.Stent graft mainly has Weaving type and laser engraving type, and wherein Weaving type bracket is according to end form
It is divided into free style braided support and closed type braided support again.Free style braided support is in freely due to the braided wires head of end
Scatter, clinically in the presence of damage vascular wall thus lead to secondary injury potential risk, therefore closed type braided support is gradually now
It is welcome.But conventional fracture of wire silk head closed manners will cause stent graft compression profile increase, use same inner diameter
Delivery conduit when, it may appear that push power excessive the problem of causing the difficult even bracket of push to place failure, and use is thicker
When some delivery conduits, and will cause conduit can not be by certain thinner blood vessels, to limit being applicable in for stenter to implant
Range.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of self-constriction formula stent grafts, are not only able to promote bracket
End can be collapsed from trend central axis, prevent the compression profile of closed type braided support from increasing, and can also be effectively reduced simultaneously
The push power of braided support.
The present invention to solve above-mentioned technical problem and the technical solution adopted is that provide a kind of self-constriction formula stent graft,
Including rack body, the rack body is formed by way of braiding, wherein during the rack body is under softened state
Empty cylinder-like structure, the braided wires end of the rack body are connected to form closed U-shaped end, and the U-shaped end and
The first slanted angle is formed between rack body central axis.
Above-mentioned self-constriction formula stent graft, wherein high molecular material is coated with outside the braided wires of the U-shaped end point
Shape memory layer;The high molecular material shape memory layer is line polymer and one kind of crosslinking polymer or combinations thereof.
Above-mentioned self-constriction formula stent graft, wherein the U-shaped end includes bottom arc sections and two extending arms,
The bottom arc sections are rolled over to rack body central axis lateral bending, are formed between the bottom arc sections and extending arm of the U-shaped end
Second slanted angle.
Above-mentioned self-constriction formula stent graft, wherein crosslinking polymer layer, institute are coated with outside the bottom arc sections
It states and is coated with linear polymeric nitride layer outside extending arm.
Above-mentioned self-constriction formula stent graft, wherein the crosslinking polymer layer is with shape memory characteristic
Racemic polylactic acid, polyglycolic acid, poly-epsilon-caprolactone, polytrimethylene carbonate, polydioxanone, polyamide, poly- ammonia
One of the derivative carbonic ester of ester, polyaminoacid monomer, or the copolymer layer of the above monomer;The linear polymeric nitride layer is tool
There is the polyethylene of shape memory characteristic, polyisoprene, polylactic acid, poly-epsilon-caprolactone, polyglycolic acid, gather to dioxa hexamethylene
One of ketone and polytrimethylene carbonate monomer, or the copolymer layer of the above monomer.
Above-mentioned self-constriction formula stent graft, wherein the crosslinking polymer layer is racemic polylactic acid, poly- ε-in oneself
The copolymer layer of ester, polydioxanone and polyamide;The linear polymeric nitride layer be polyisoprene, poly-epsilon-caprolactone,
The copolymer layer of polyglycolic acid, poly-p-dioxanone and polytrimethylene carbonate.
Above-mentioned self-constriction formula stent graft, wherein the length L of the U-shaped end is U-shaped head bottom part arc sections half
1~5 times of diameter R.
Above-mentioned self-constriction formula stent graft, wherein the radius R of the U-shaped head bottom part arc sections is 1~10mm,
The number of the U-shaped end is 4~144.
Above-mentioned self-constriction formula stent graft, wherein the braided wires of the rack body are handled by thermal finalization, described
First slanted angle range is 30~60 degree, and the second slanted angle range is 15~30 degree.
The present invention, which compares the prior art, to be had following the utility model has the advantages that self-constriction formula stent graft provided by the invention, U-shaped
There are slanted angles with rack body for end, and when compressed stent enters sheath, above-mentioned slanted angle be will increase, to generate a direction
The internal stress of stent graft central axis, this internal stress can promote all U-shaped ends of bracket end can be from trend central axis
It collapses, thus overall size when not only reducing stent graft compressive state, and braiding branch can also be effectively reduced simultaneously
The push power of frame.In addition, the fatigue performance of braided support can be improved in the present invention, pushed away repeatedly when can effectively increase stenter to implant
The number for sending and recycling, facilitates doctor more precisely to place bracket.
Detailed description of the invention
Fig. 1 is self-constriction formula stent graft structural schematic diagram of the present invention;
Fig. 2 is the U-shaped end structure enlarged diagram of self-constriction formula stent graft of the present invention.
Specific embodiment
The invention will be further described with reference to the accompanying drawings and examples.
Fig. 1 is self-constriction formula stent graft structural schematic diagram of the present invention;Fig. 2 is self-constriction formula stent graft of the present invention
U-shaped end structure enlarged diagram.
Referring to Figure 1 and Fig. 2, self-constriction formula stent graft provided by the invention, including rack body 1, the bracket
Ontology 1 is formed by way of braiding, wherein the rack body 1 is in hollow cylinder-like structure under softened state, described
The braided wires end of rack body 1 is connected to form closed U-shaped end 2, and the U-shaped end 2 and 1 central axis of rack body it
Between form the first slanted angle.Stent graft provided by the invention, there are slanted angle, pressures with rack body 1 for U-shaped end 2
When contracting bracket enters sheath, above-mentioned slanted angle be will increase, so that an internal stress towards stent graft central axis is generated, this
Internal stress can promote all U-shaped ends 2 of bracket end that can collapse from trend central axis, to reduce stent graft compression
Overall size when state.
In order to preferably make U-shaped end 2, there are slanted angle, self-constriction formula branch provided by the invention with rack body 1
Frame implantation material is coated with high molecular material shape memory layer outside the braided wires at the U-shaped end 2;The high molecular material shape
It is line polymer and one kind of crosslinking polymer or combinations thereof that shape, which remembers layer,.The U-shaped end 2 include bottom arc sections and
Two extending arms, the bottom arc sections are rolled over to rack body central axis lateral bending, the bottom arc sections of the U-shaped end 2 and are stretched
The second slanted angle is formed between swing arm.The length L of the U-shaped end 2 is 1~5 times of U-shaped head bottom part arc sections radius R.
The radius R of the 2 bottom arc sections of U-shaped end is 1~10mm, and the number of the U-shaped end 2 is 4~144.
Further, the different high molecular material of coating is contemplated that outside the bottom arc sections of U-shaped end 2 and two extending arms
Shape memory layer.Preferably, it is coated with crosslinking polymer layer outside the bottom arc sections, is coated with outside the extending arm linear
Polymeric layer.The crosslinking polymer layer is racemic polylactic acid with shape memory characteristic, polyglycolic acid, poly- ε-in oneself
One of the derivative carbonic ester of ester, polytrimethylene carbonate, polydioxanone, polyamide, polyurethane, polyaminoacid is single
Body, or the copolymer layer of the above monomer;The linear polymeric nitride layer is polyethylene, poly- isoamyl two with shape memory characteristic
One of alkene, polylactic acid, poly-epsilon-caprolactone, polyglycolic acid, poly-p-dioxanone and polytrimethylene carbonate are single
Body, or the copolymer layer of the above monomer.
Preferably, the crosslinking polymer layer is racemic polylactic acid, poly-epsilon-caprolactone, polydioxanone and polyamides
The copolymer layer of amine;The linear polymeric nitride layer is polyisoprene, poly-epsilon-caprolactone, polyglycolic acid, gathers to dioxane
The copolymer layer of hexanone and polytrimethylene carbonate.
Self-constriction formula stent graft provided by the invention, specific preparation use process is as follows: first can be to rack body 1
Braided wires carry out thermal finalization processing;It is then woven into type, and different high molecular materials is applied to the braided wires at U-shaped end 2
Shape memory layer;Then, deformation is carried out by heating to the stent graft of original-shape, then cooling is freezed so that U-shaped end
First 2 form different slanted angles, and first slanted angle ranges preferably from 30~60 degree, the second slanted angle range
Preferably 15~30 degree.Due to U-shaped end 2, there are slanted angles with rack body 1, when compressed stent enters sheath, above-mentioned inclination folder
Angle will increase, to generate an internal stress towards stent graft central axis, this internal stress can promote bracket end
All U-shaped ends can be collapsed from trend central axis, thus overall size when not only reducing stent graft compressive state, and
And the push power of braided support can also be effectively reduced simultaneously.After conveying in place, original-shape is reverted to by external world's heating.
Although the present invention is disclosed as above with preferred embodiment, however, it is not to limit the invention, any this field skill
Art personnel, without departing from the spirit and scope of the present invention, when can make a little modification and perfect therefore of the invention protection model
It encloses to work as and subject to the definition of the claims.
Claims (9)
1. a kind of self-constriction formula stent graft, including rack body, the rack body are formed by way of braiding, special
Sign is that the rack body is in hollow cylinder-like structure, the braided wires end phase of the rack body under softened state
Company forms closed U-shaped end, and forms the first slanted angle between the U-shaped end and rack body central axis.
2. self-constriction formula stent graft as described in claim 1, which is characterized in that outside the braided wires of the U-shaped end point
Coated with high molecular material shape memory layer;The high molecular material shape memory layer is line polymer and crosslinking polymer
One kind or combinations thereof.
3. self-constriction formula stent graft as claimed in claim 2, which is characterized in that the U-shaped end includes bottom circular arc
Portion and two extending arms, the bottom arc sections to rack body central axis lateral bending roll over, the bottom arc sections of the U-shaped end and
The second slanted angle is formed between extending arm.
4. self-constriction formula stent graft as claimed in claim 2, which is characterized in that be coated with friendship outside the bottom arc sections
Connection type polymeric layer, the extending arm are coated with linear polymeric nitride layer outside.
5. self-constriction formula stent graft as claimed in claim 4, which is characterized in that the crosslinking polymer layer be with
The racemic polylactic acid of shape memory characteristic, poly-epsilon-caprolactone, polytrimethylene carbonate, is gathered to dioxocyclohex polyglycolic acid
One of the derivative carbonic ester of ketone, polyamide, polyurethane, polyaminoacid monomer, or the copolymer layer of the above monomer;The line
Shape polymeric layer be polyethylene with shape memory characteristic, polyisoprene, polylactic acid, poly-epsilon-caprolactone, polyglycolic acid,
One of poly-p-dioxanone and polytrimethylene carbonate monomer, or the copolymer layer of the above monomer.
6. self-constriction formula stent graft as claimed in claim 5, which is characterized in that the crosslinking polymer layer is racemization
Polylactic acid, poly-epsilon-caprolactone, polydioxanone and polyamide copolymer layer;The linear polymeric nitride layer is poly- isoamyl two
Alkene, poly-epsilon-caprolactone, polyglycolic acid, poly-p-dioxanone and polytrimethylene carbonate copolymer layer.
7. self-constriction formula stent graft as claimed in claim 3, which is characterized in that the length L of the U-shaped end is U-shaped
1~5 times of head bottom part arc sections radius R.
8. self-constriction formula stent graft as claimed in claim 7, which is characterized in that the U-shaped head bottom part arc sections
Radius R is 1~10mm, and the number of the U-shaped end is 4~144.
9. self-constriction formula stent graft as claimed in claim 3, which is characterized in that the braided wires of the rack body are passed through
Thermal finalization processing, the first slanted angle range are 30~60 degree, and the second slanted angle range is 15~30 degree.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201910362245.1A CN109998750B (en) | 2019-04-30 | 2019-04-30 | Self-contraction type stent implant |
Applications Claiming Priority (1)
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CN201910362245.1A CN109998750B (en) | 2019-04-30 | 2019-04-30 | Self-contraction type stent implant |
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CN109998750A true CN109998750A (en) | 2019-07-12 |
CN109998750B CN109998750B (en) | 2023-09-15 |
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CN201910362245.1A Active CN109998750B (en) | 2019-04-30 | 2019-04-30 | Self-contraction type stent implant |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113288314A (en) * | 2021-01-06 | 2021-08-24 | 微创神通医疗科技(上海)有限公司 | Vascular implant and medical equipment |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU3124699A (en) * | 1994-07-28 | 1999-08-05 | Medinol Ltd | A stent |
US20030216804A1 (en) * | 2002-05-14 | 2003-11-20 | Debeer Nicholas C. | Shape memory polymer stent |
EP1527751A1 (en) * | 2003-10-28 | 2005-05-04 | DEUTSCHE INSTITUTE FÜR TEXTIL- UND FASERFORSCHUNG STUTTGART Stiftung des öffentlichen Rechts | Tubular Implant |
US20110251364A1 (en) * | 2006-10-25 | 2011-10-13 | Anthamatten Mitchell L | Shape Memory Polymers |
CN103709691A (en) * | 2012-10-09 | 2014-04-09 | 上海微创医疗器械(集团)有限公司 | Biodegradable cross-linked polymer, and preparation method thereof |
US20140142683A1 (en) * | 2012-11-21 | 2014-05-22 | Lee Core | Stent with elastomeric elements |
DE102018125983A1 (en) * | 2017-10-20 | 2019-04-25 | Acandis Gmbh | stent |
-
2019
- 2019-04-30 CN CN201910362245.1A patent/CN109998750B/en active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU3124699A (en) * | 1994-07-28 | 1999-08-05 | Medinol Ltd | A stent |
US20030216804A1 (en) * | 2002-05-14 | 2003-11-20 | Debeer Nicholas C. | Shape memory polymer stent |
EP1527751A1 (en) * | 2003-10-28 | 2005-05-04 | DEUTSCHE INSTITUTE FÜR TEXTIL- UND FASERFORSCHUNG STUTTGART Stiftung des öffentlichen Rechts | Tubular Implant |
US20110251364A1 (en) * | 2006-10-25 | 2011-10-13 | Anthamatten Mitchell L | Shape Memory Polymers |
CN103709691A (en) * | 2012-10-09 | 2014-04-09 | 上海微创医疗器械(集团)有限公司 | Biodegradable cross-linked polymer, and preparation method thereof |
US20140142683A1 (en) * | 2012-11-21 | 2014-05-22 | Lee Core | Stent with elastomeric elements |
DE102018125983A1 (en) * | 2017-10-20 | 2019-04-25 | Acandis Gmbh | stent |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113288314A (en) * | 2021-01-06 | 2021-08-24 | 微创神通医疗科技(上海)有限公司 | Vascular implant and medical equipment |
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