CN1099967A - Depth meter for locating optic fibre probe inserting in organism soft tissue - Google Patents

Depth meter for locating optic fibre probe inserting in organism soft tissue Download PDF

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Publication number
CN1099967A
CN1099967A CN 93117423 CN93117423A CN1099967A CN 1099967 A CN1099967 A CN 1099967A CN 93117423 CN93117423 CN 93117423 CN 93117423 A CN93117423 A CN 93117423A CN 1099967 A CN1099967 A CN 1099967A
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CN
China
Prior art keywords
utensil
probe
pore
utensil according
soft tissue
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Pending
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CN 93117423
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Chinese (zh)
Inventor
谢树森
周川钊
陈光敏
任重
林祺榕
陈荣
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Fujian Normal University
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Fujian Normal University
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Priority to CN 93117423 priority Critical patent/CN1099967A/en
Publication of CN1099967A publication Critical patent/CN1099967A/en
Pending legal-status Critical Current

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  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Length Measuring Devices By Optical Means (AREA)

Abstract

The depth meter having model-I and model-II can measure the depth of microprobe of optical fibre in soft tissue and locate it at predetermined position. Its reading mechanism can precisely report the depth value. Its inserting/drawback unit and locating unit can correctly put the microprobe to predetermined position. The model-II also has 2-D regulation function to obtain needed angle.

Description

Depth meter for locating optic fibre probe inserting in organism soft tissue
The present invention relates to a kind of miniature probe with optical fiber probe and insert and be positioned predetermined point position in mammal (comprising the people) the soft tissue body, and measure the utensil that miniature probe arrives the degree of depth in the organizer, belong to the Biomedical Instruments class that laboratory uses.
In the Laser Biomedicine research field, need be in organizer a certain predetermined point receives or the emission light radiant flux, to reach the radiation energy flow rate of measuring this point or from the purpose of these irradiation organizer.Usual practice is to utilize entry needle to draw the hole in the organizer measuring position, and the optical fibers probe that then will have miniature probe inserts in the organizer, to achieve the above object.In order to measure the one dimension degree of depth between predetermined point and organizer surface exactly, put before the people on optical fiber reference mark in advance, be inserted into the back and calculate miniature probe with the method for subduction and insert and organize the intravital degree of depth.So far still do not have a kind of optical fiber of accurately measuring both at home and abroad and insert the animal body soft tissue one dimension degree of depth, and make light probe localized special implement in organizer.Recent two decades is not found the report relevant with the present invention about " measuring the degree of depth and the localized utensil of probe that light probe is inserted the animal body soft tissue " data, document by retrieval.
As mentioned above, adopt existing manual manipulation method, the depth value anthropic factor of measuring is big, and fibre-optical probe is difficult in rubber-like soft tissue body to obtain stable location, and measurement error is big, can not satisfy the requirement of research work.The objective of the invention is to overcome above-mentioned shortcoming, provide a kind of optical fiber miniature probe of accurately measuring to insert the intravital degree of depth of mammal body (comprising human body) soft tissue and make probe obtain the utensil of stable position at a certain predetermined point, and utilize this utensil to cooperate with photodetector system, be used for measuring the radiation energy flow rate of each space coordinates point of soft tissue body, carry out the correlational study in Laser Biomedicine field.In order to realize purpose of the present invention, design the different structure form that two kinds on optical fiber probe depth meter for locating I type and II type belongs to same inventive concept.
The present invention realizes as follows: this utensil inserts the soft tissue body by survey measurements mechanism, pore-creating pin and forms with part backing mechanism, location flat board.Structure II type also has two-dimentional orientation governor motion.The optical fibers probe that has miniature probe passes the central channel or the axle center hole of whole utensil, arrives pore-creating pin needle point end.When adjusting pore-creating pin needle point is in the organizer surface location, the reading that survey measurements mechanism provides is an initial reading, regulate the pore-creating pin and insert a certain predetermined point in the soft tissue body, the reading that survey measurements mechanism provides is reading not, and the difference of twice reading value is pore-creating pin or optical fiber miniature probe and enters and organize intravital depth value.When making pore-creating pin part rollback by backspace mechanism, then the optical fiber miniature probe fully exposes and is stabilized in and organizes on the intravital predetermined point, to finish in the organizer luminous flux detection or by photoconduction organizer to be implemented task such as rayed.
Concrete structure of the present invention and embodiment are further specified by the following drawings.
Figure one: optical fiber probe depth meter for locating I type front view
Figure two: optical fiber probe depth meter for locating II type front view
Figure three: optical fiber probe depth meter for locating II type side view
Figure four: optical fiber probe depth meter for locating I type, the application example figure that light radiation distributes in measuring Mus live body soft tissue.
Figure one: the structure of having described optical fiber probe depth meter for locating I type.Main scale 8, secondary chi 9, micrometric screw 10 are formed micrometer formula reading mechanism.Slip guide 7, stage clip 4, pore-creating pin 3, guide pipe 2 are formed the insertion mechanism of pore-creating pin 3.Elongated slot 13 on lock-screw 12, small pressure spring 5, pore-creating pin 3, slip guide 7 sidewalls is formed the part backing mechanism of pore-creating pin 3.
The bottom of guide pipe 2 cements at the B point with the dull and stereotyped 1 usefulness adhesive glue in location among the figure one, and its upper end and main scale 8 are fixed into one.Location dull and stereotyped 1 is made by transmissive ultraviolet, material visible, near-infrared radiation, as making with optical glass material.The optical fibers probe 11 that has a miniature probe 14 runs through axle center hole from depth meter for locating and arrives pore-creating pin 3 needle point ends, and the A place in slip guide 7 cements optical fiber probe 11 with adhesive glue, makes it and the guide 7 that slides becomes one.One rectangle elongated slot is arranged on the sidewall of slip guide 7, loosen lock-screw 12 and can make pore-creating pin 3 under the effect of small pressure spring 5, in the length range of elongated slot, upwards pore-creating pin 3 is upspring, pore-creating pin 3 is to the top rollback, and the miniature probe 14 in the pin hole is exposed in the organizer fully.The enough elastic force of stage clip 4 guarantees that slip guide 7 keeps closely contacting with screw rod 10 lower surfaces all the time.
Before the measurement, unclamp lock-screw 12, lock after making lock-screw 12 be in the centre position of sidewall elongated slot 13 of slip guide 7 position of adjusting pore-creating pin 3, and revolute chi 9 makes the needle point of pore-creating pin 3 flush with dull and stereotyped 1 lower surface, location, and the reading (initial reading) on the main scale 8 is 2.46mm at this moment.Depth meter for locating is placed on the tested soft tissue body, and location dull and stereotyped 1 and the surface of soft tissue body produce one and stable contact the zonule to locate.Revolute chi 9, miniature probe 14 in pore-creating pin 3 and the pin hole is entered in the organizer, and arrive the predetermined point position, and the reading (not reading) on the main scale 8 is 7.61mm at this moment, the difference of front and back reading: 7.61-2.46=5.15mm promptly is that miniature probe 14 enters the depth value in the organizer.When a certain wavelength laser bundle of needs goes to shine organizer or by in the optical fiber miniature probe 14 tissue receiving bodies during light radiation through optical fiber miniature probe 14, unclamp lock-screw 12, under the effect of small pressure spring 5 with pore-creating pin 3 part rollback back, optical fiber miniature probe 14 is fully exposed, to finish the function of launching or accepting light radiation.
Figure two, figure three have described the structure of optical fiber probe depth meter for locating II type.Main scale 8, secondary chi 9 constitute the cursor type reading mechanism.Hand wheel pole 21, vernier 23, trimming hand wheel 24, pore-creating needle rack 25, secondary chi 9 are formed insertion and part backing mechanism.Rotating shaft 15, lock-screw 16, lifting nut 17, column 18 are formed two-dimentional orientation governor motion.
The optical fiber 11 that has miniature probe among the figure two runs through the central channel of depth meter for locating II type from top to bottom, and miniature probe 14 arrives the needle point ends, and optical fiber probe 11 cements at A place and vernier 23 and is integral.Column 18 is fixed on a side of workbench 19, the adjusting of lifting nut 17 can make depth meter for locating move up and down, rotating shaft 15 is used with lock-screw 16, makes optical fiber probe in required arbitrary angle of inclination work, and its angle of regulation range can be selected between vertical ± 60 °.The location flat board 1 that the lower surface of guide pipe 2 has a transmissive ultraviolet, material visible, near-infrared radiation to make, and fixing at B place and guide pipe 2 bondings.Location dull and stereotyped 1 can be made by optical glass material.Main scale 8 connects with figure two shafts 15 by coupling block among the figure three, rotation hand wheel bar 21 can make vernier 23 move up and down with the lower part, trimming hand wheel 24 is done counterclockwise, and rotation moves up pore-creating needle rack 25, its amplitude is embodied by the secondary chi 9 of vernier, generally should be greater than 1.5mm, to guarantee the abundant exposure of miniature probe 14.The depth value that optical fiber probe depth meter for locating II type is surveyed, the calculating means of twice reading value subduction carries out before and after still adopting.
During measurement, tested live body soft tissue is placed on the workbench 19, regulate trimming hand wheel 24, the needle point of pore-creating pin 3 is flushed with dull and stereotyped 1 lower surface, location, the reading that provides on the record main scale 8 is 3.87mm.Unclamp lock-screw 16, regulate rotating shaft 15, make the optical fiber probe axis be adjusted at fixing and locking screw 16 after inclined to one side 45 ° of the vertical.Rotation and lifting nut 17 makes location dull and stereotyped 1 and soft tissue surface produce one and stable contacts the zonule to locate.Rotation hand wheel bar 21 makes vernier 23 move down with the lower part.When pore-creating pin 3 arrived a certain predetermined point together with optical fiber probe insertion soft tissue, the reading that provides on the record main scale 8 was 8.89mm, and the difference of former and later two readings: 8.89-3.87=5.02mm represents that promptly miniature probe 14 enters the intravital degree of depth of soft tissue.When selecting a certain wavelength laser bundle through optical fiber probe irradiation organizer, rotate trimming hand wheel 24 and make pore-creating pin 3 predetermined point rollback 1.5mm in the organizer, miniature probe 14 can fully expose.
Figure four has described and has utilized optical fiber probe depth meter for locating I type measurement miniature probe to enter the degree of depth of certain predetermined point in the Mus tumor tissues and utilize this depth meter for locating to cooperate with photodetector, measures an application examples of radiation energy flow rate in the tumor tissues.Postanesthetic Mus alive is fixed on the workbench 19, regulates pore-creating pin needle point and make it to flush with locating flat board 1, the initial reading on the registered depth instrument is 2.78mm.Allow location dull and stereotyped 1 gently be pressed on soft tissue (tumor tissues) surface, produce a stable plane contact zonule and position.Location dull and stereotyped 1 is made by optical glass.Secondary chi on the rotation depth meter for locating, make miniature probe 14 under the guiding of pore-creating pin, enter a certain preposition in the organizer, reading on the depth meter for locating is 7.18mm at this moment, and the difference 7.18-2.78=4.40mm of twice reading value is the depth value that light probe 14 enters organizer.Loosen lock-screw and make pore-creating pin rollback, miniature probe 14 fully exposes and is stabilized on the original predetermined point.With the tested position of laser beam G irradiation organizer, the luminous flux that all directions scatter to measurement point in the tumor tissues body is transferred to photodetector F by optical fiber probe 11 and is received by miniature probe 14 collections, can record the radiation energy flow rate of this measurement point.
Optical fiber probe depth meter for locating I type provided by the present invention and II type, owing to adopted positioner and backspace mechanism, the probe of inserting can not be moved in overall optical radiation, irradiation and testing process, overcome the influence that the soft tissue strain produces, probe can accurately be located in organizer, guaranteed the reliability of measurement data.Simultaneously, owing to adopted the dip stick structure of micrometer and slide gauge, the numerical value degree of accuracy height that degree of depth instrument is measured, the error of having avoided anthropic factor to bring, certainty of measurement is ± 0.05mm.

Claims (19)

1, predetermined point in mammal (comprising the people) the soft tissue body is inserted and be positioned to a kind of miniature probe with optical fiber probe, and the energy measurement miniature probe arrives the utensil of the degree of depth in the organizer, it is characterized in that this utensil inserts the soft tissue body by micrometer formula reading mechanism, pore-creating pin and part backing mechanism, location flat board constitute, the axle center hole that the optical fibers probe 11 that has a miniature probe 14 runs through this utensil arrives in the pin hole of pore-creating pin 3.
2, utensil according to claim 1 is characterized in that micrometer formula reading mechanism is made up of the main scale in the micrometer 8, secondary chi 9, micrometric screw 10.
3, utensil according to claim 2 is characterized in that regulating secondary chi 9 slip guide 7 following mechanisms are moved up and down thereupon.
4, utensil according to claim 1, the guide 7 that it is characterized in that sliding, stage clip 4, pore-creating pin 3, guide pipe 2 are formed insertion mechanism.
5, utensil according to claim 1 is characterized in that the elongated slot 13 on lock-screw 12, small pressure spring 5, pore-creating pin 3, slip guide 7 sidewalls is formed pore-creating pin part backing mechanism.
6, the location flat board 1 that utensil according to claim 1, the lower surface that it is characterized in that guide pipe 2 have a transmissive ultraviolet, material visible, near-infrared radiation to make, and fix in B place bonding.
7, utensil according to claim 6 is characterized in that the location flat board 1 in this utensil is made by optical glass.
8, utensil according to claim 1 is characterized in that the A place of optical fiber probe 11 in slip guide 7, with adhesive glue it is cemented fixingly, and optical fiber probe 11 and slip guide 7 are become one.
9, predetermined point in mammal (comprising the people) the soft tissue body is inserted and be positioned to a kind of miniature probe with optical fiber probe, and the energy measurement miniature probe arrives the utensil of the degree of depth in the organizer, it is characterized in that this utensil inserts soft tissue by cursor type reading mechanism, pore-creating pin and part backing mechanism, location flat board and orientation governor motion are formed, the optical fibers probe 11 that has a miniature probe 14 runs through in the pin hole of central channel arrival pore-creating pin 3 of this utensil.
10, utensil according to claim 9 is characterized in that hand wheel pole 21, vernier 23, trimming hand wheel 24, pore-creating needle rack 25, secondary chi 9 compositions insert and the part backing mechanism.
11, utensil according to claim 9 is characterized in that survey measurements mechanism is made of main scale 8, vernier 23.
12, according to claim 10 and 11 described utensils, it is characterized in that hand wheel pole 21 and main scale 8 constitute screw pair, the rotation of hand wheel pole 21 directly promotes the mechanism of vernier below 23 and moves up and down.
13, the location flat board 1 that utensil according to claim 9, the lower surface that it is characterized in that guide pipe 2 have a transmissive ultraviolet, material visible, near-infrared radiation to make, and fix in B place bonding.
14, utensil according to claim 13 is characterized in that location dull and stereotyped 1 made by optical glass.
15, utensil according to claim 9 is characterized in that rotating shaft 15, lock-screw 16, lifting nut 17, column 18 form the orientation governor motion of these utensils.
16, utensil according to claim 15 is characterized in that being used of rotating shaft 15 and lock-screw 16, and this utensil is worked with arbitrary angle of inclination.
17, utensil according to claim 16 is characterized in that the inclination angle of this utensil can be selected between vertical ± 60 °.
18, utensil according to claim 15 is characterized in that regulating lifting nut 17, and this utensil is moved up and down.
19, utensil according to claim 9 is characterized in that optical fiber probe 11 becomes one at A place and vernier 23 bondings.
CN 93117423 1993-09-08 1993-09-08 Depth meter for locating optic fibre probe inserting in organism soft tissue Pending CN1099967A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 93117423 CN1099967A (en) 1993-09-08 1993-09-08 Depth meter for locating optic fibre probe inserting in organism soft tissue

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Application Number Priority Date Filing Date Title
CN 93117423 CN1099967A (en) 1993-09-08 1993-09-08 Depth meter for locating optic fibre probe inserting in organism soft tissue

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CN1099967A true CN1099967A (en) 1995-03-15

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103057329A (en) * 2012-08-05 2013-04-24 余克勤 Support on mechanical carving tool
CN104000648A (en) * 2014-05-15 2014-08-27 南华大学 Positioning platform of sighting device positioning device
CN104842351A (en) * 2015-06-04 2015-08-19 尹中元 Bedside mechanical arm for auxiliary positioning in stereotactic biopsy
CN112432939A (en) * 2020-11-26 2021-03-02 上海化工院检测有限公司 Optical fiber Raman probe device with drilling function and using method

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103057329A (en) * 2012-08-05 2013-04-24 余克勤 Support on mechanical carving tool
CN104000648A (en) * 2014-05-15 2014-08-27 南华大学 Positioning platform of sighting device positioning device
CN104000648B (en) * 2014-05-15 2016-01-20 南华大学 The locating platform of sight positioner
CN104842351A (en) * 2015-06-04 2015-08-19 尹中元 Bedside mechanical arm for auxiliary positioning in stereotactic biopsy
CN112432939A (en) * 2020-11-26 2021-03-02 上海化工院检测有限公司 Optical fiber Raman probe device with drilling function and using method

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