CN109966512A - A kind of facial mask and its application for detecting sensitive skin - Google Patents

A kind of facial mask and its application for detecting sensitive skin Download PDF

Info

Publication number
CN109966512A
CN109966512A CN201910199360.1A CN201910199360A CN109966512A CN 109966512 A CN109966512 A CN 109966512A CN 201910199360 A CN201910199360 A CN 201910199360A CN 109966512 A CN109966512 A CN 109966512A
Authority
CN
China
Prior art keywords
facial mask
liquid
detection agent
sensitive detection
sensitive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910199360.1A
Other languages
Chinese (zh)
Inventor
张芝华
廖筝筝
聂菁
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Yi Chemical Co Ltd
Original Assignee
Shanghai Yi Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Yi Chemical Co Ltd filed Critical Shanghai Yi Chemical Co Ltd
Priority to CN201910199360.1A priority Critical patent/CN109966512A/en
Publication of CN109966512A publication Critical patent/CN109966512A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/445Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0006Skin tests, e.g. intradermal testing, test strips, delayed hypersensitivity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Cosmetics (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)

Abstract

The invention discloses a kind of easy to carry, the facial mask for being used to detect sensitive skin easy to use, the facial mask includes face mask substrate material and facial mask liquid, the facial mask liquid is made of cosmetic base and sensitive detection agent, wherein, sensitive detection agent is any one or a few in Phenoxyethanol, lactic acid, capsaicine, lauryl sodium sulfate and hydroxybenzoate, wherein, cosmetic base by 2.0 ~ 4.0% 1,3 butanediols, the water of 0.1 ~ 0.3% xanthan gum, 1.0 ~ 3.0% glycerol, 0.5 ~ 2.0% NaCl and surplus forms.The present invention discloses a kind of methods using facial mask detection sensitive skin, include the following steps: 1) to prepare facial mask of the present invention;2) facial mask is spread on into face, perception is with the presence or absence of stimulation;3) it stimulates if it exists, records stimulation location and stimulation time, evaluate skin sensitivity degree.Detection method of the invention is simple to operation, can complete detection sensitive skin, have well application and market prospects.

Description

A kind of facial mask and its application for detecting sensitive skin
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of facial mask and its application for detecting sensitive skin.
Background technique
Sensitive refers in particular to a kind of high reactiveness that skin occurs under physiology or pathological conditions, takes place mostly in face Portion, clinical manifestation are that scorching hot, shouting pain, itch and tight feeling etc. easily occurs in skin when being stimulated by factors such as physics, chemistry, spirit Subjective symptom, companion or not companion's objective signs such as erythema, the scales of skin that peel off, telangiectasis.The possible triggering factors master of sensitive Have: (1) physical factor: such as season alternation, temperature change, solarization;(2) chemical factor: such as cosmetics, cleaning supplies, disinfection The externally applied drug of the irritations such as product, Tretinoin, environmental contaminants (such as haze, dust, tail gas);(3) mental element: such as anxiety, suppression It is strongly fragrant etc..Sensitive has higher incidence in countries in the world, wherein and Asia women incidence is 40%~55.98%, China's women incidence is about 36.1%.In recent years, on the one hand with environmental pollution, the increase of stress, so that sensibility Dermatosis incidence constantly increases;On the other hand the raising with people's living standard and to sensitive understanding, sensibility skin Skin is more and more concerned.Feel is that people's (self-induction sensitivity flesh) of sensitive flesh is significantly increasing year by year, sensitive flesh Although not being a kind of skin disease, it does not tolerate the personal care products such as environmental stimuli and cosmetics, and serious person can also result in Unhealthy emotion and psychic problems reduce quality of life.
China has formulated " Chinese sensitive specialist common recognition " in 2017, assesses sensitive flesh wherein defining Method, and list diagnosis required essential condition and secondary conditions.The evaluation method of sensitive is more, including subjectivity is commented Valence (sensitive questionnaire), half subjective assessment (lactic acid prick test, capsaicine test, lauryl sodium sulfate examination Test) and objectively evaluate (transepidermal water loss rate measurement, water content of stratum corneum measurement, pH value measurement, sebum level measurement, epidermis The Non-invaive examinations such as skin coloration analyzer, Reflectance confocal microscope and functional magnetic resonance imaging).Wherein, questionnaire survey Table is considered as diagnostic sensitivity skin the best way, however this method lacks persuasion often with very strong subjectivity, And lactic acid and capsaicine prick test need to be completed in the case where related personnel instructs, test request is higher, and high concentration lactic acid or peppery It is mostly the wing of nose that green pepper element, which smears range, and there are limitations, can not be accurate, comprehensive for sensitive part is not in the crowd of the wing of nose Evaluate whether it is sensitive skin.Accordingly, develop it is a kind of simple, be effectively used for detecting and judging whether oneself belongs to sensitive flesh Effective ways be of great significance.
Summary of the invention
In view of the deficiencies of the prior art, the present invention is intended to provide a kind of product and inspection that can be used in detecting sensitive skin Survey sensitive skin method, to realize it is quick, convenient, comprehensive, reliably detect sensitive skin.
As the first aspect of the present invention, the present invention provides a kind of Phenoxyethanol as sensitive detection agent quick for detecting Feel the purposes in skin.
Preferably, the Phenoxyethanol is included in facial mask.
Preferably, the facial mask includes face mask substrate material and facial mask liquid, contain by weight percentage in the facial mask liquid The Phenoxyethanol of meter 0.01~1.0%.
Preferably, also containing by weight percentage 99.0~99.99% cosmetic base in the facial mask liquid.
Preferably, the cosmetic base comprises the following raw materials by weight percent:
Preferably, the preparation method of the facial mask, comprising the following steps:
1) after dispersing xanthan gum with 1,3-BDO plus water is warming up to 80~85 DEG C, and stirring and dissolving is uniform, heat preservation 15min obtains mixed liquor;
2) mixed liquor that the step 1) obtains is cooled to after 40~45 DEG C and sequentially adds Phenoxyethanol, glycerol and NaCl is stirred 15~25 minutes, is cooled to 30~35 DEG C, obtains facial mask liquid;
3) facial mask liquid that the step 2) obtains is stored in face mask substrate material, obtains facial mask.
Preferably, face mask substrate material described in the step 3) is non-woven fabrics, silk fabric, biological fiber, nanofiber In any one.
As a second aspect of the invention, the present invention provides a kind of for detecting the facial mask of sensitive skin.
Preferably, containing sensitive detection agent in the facial mask.
Preferably, the facial mask includes face mask substrate material and facial mask liquid, contain sensitive detection agent in the facial mask liquid.
Preferably, the sensitive detection agent contained in the facial mask liquid is Phenoxyethanol, lactic acid, capsaicine, dodecyl Any one or a few in sodium sulphate or hydroxybenzoate.
Preferably, when sensitive detection agent is Phenoxyethanol, the weight hundred of the Phenoxyethanol contained in the facial mask liquid Divide than being 0.01~1.0%.
Preferably, the weight percent of the lactic acid contained in the facial mask liquid is 4.0 when sensitive detection agent is lactic acid ~6.0%.
Preferably, when sensitive detection agent is capsaicine, the weight percent of the capsaicine contained in the facial mask liquid It is 0.01~0.03%.
Preferably, when sensitive detection agent is dodecyl sodium sulfate, the dodecyl sulphur that contains in the facial mask liquid The weight percent of sour sodium is 5.0~8.0%.
Preferably, when sensitive detection agent is hydroxybenzoate, the hydroxybenzoate that contains in the facial mask liquid Weight percent be 0.1~0.3%.
Preferably, also containing cosmetic base in the facial mask.
Preferably, the cosmetic base comprises the following raw materials by weight percent:
Preferably, the preparation method of the facial mask, comprising the following steps:
1) after dispersing xanthan gum with 1,3-BDO plus water is warming up to 80~85 DEG C, and stirring and dissolving is uniform, heat preservation 15min obtains mixed liquor;
2) mixed liquor that the step 1) obtains is cooled to after 40~45 DEG C and sequentially adds sensitive detection agent, glycerol and NaCl is stirred 15~25 minutes, is cooled to 30~35 DEG C, obtains facial mask liquid;
3) facial mask liquid that the step 2) obtains is stored in face mask substrate material, obtains facial mask.
Preferably, face mask substrate material described in the step 3) is non-woven fabrics, silk fabric, biological fiber, nanofiber In any one.
As the third aspect of the present invention, the present invention provides a kind of for detecting the facial mask of sensitive skin.
Preferably, the facial mask includes face mask substrate material and facial mask liquid, which is characterized in that face mask substrate material every square centimeter In the Phenoxyethanol containing 0.005~0.75mg.
Preferably, also containing the cosmetic base of 49.5~74.9925mg in face mask substrate material every square centimeter.
Preferably, the cosmetic base comprises the following raw materials by weight percent:
Preferably, the preparation method of the facial mask, comprising the following steps:
1) after dispersing xanthan gum with 1,3-BDO plus water is warming up to 80~85 DEG C, and stirring and dissolving is uniform, heat preservation 15min obtains mixed liquor;
2) mixed liquor that the step 1) obtains is cooled to after 40~45 DEG C and sequentially adds Phenoxyethanol, glycerol and NaCl stirs 15~25 minutes, after being cooled to 30~35 DEG C, obtains facial mask liquid;
3) facial mask liquid that the step 2) obtains is stored in face mask substrate material, obtains facial mask.
Preferably, face mask substrate material described in the step 3) is non-woven fabrics, silk fabric, biological fiber, nanofiber In any one.
As the fourth aspect of the present invention, the present invention provides a kind of method using facial mask detection sensitive skin.
Preferably, the method, includes the following steps:
1) it prepares a kind of for detecting the facial mask of sensitive skin, sensitive detection agent is contained in the facial mask;
2) facial mask prepared by step 1) is spread on into human skin, perception is with the presence or absence of stimulation;
3) it stimulates if it exists, records stimulation location and stimulation time, evaluate skin sensitivity degree.
Preferably, the facial mask in the step 1) includes face mask substrate material and facial mask liquid, wherein contain in the facial mask liquid Cosmetic base and sensitive detection agent.
Preferably, the sensitive detection agent contained in the facial mask liquid is Phenoxyethanol, lactic acid, capsaicine, dodecyl Any one or a few in sodium sulphate and hydroxybenzoate.
Preferably, containing by weight percentage 0.01 in the facial mask liquid when sensitive detection agent is Phenoxyethanol ~1.0% Phenoxyethanol and 99.0~99.99% cosmetic base.
Preferably, when sensitive detection agent is lactic acid, in the facial mask liquid containing by weight percentage 4.0~ 6.0% lactic acid and 94.0~96.0% cosmetic base.
Preferably, when sensitive detection agent is capsaicine, in the facial mask liquid containing by weight percentage 0.01~ 0.03% capsaicine and 99.97~99.99% cosmetic base.
Preferably, when sensitive detection agent is dodecyl sodium sulfate, containing by weight percentage in the facial mask liquid Count 5.0~8.0% dodecyl sodium sulfate and 92.0~95.0% cosmetic base.
Preferably, when sensitive detection agent is hydroxybenzoate, containing by weight percentage in the facial mask liquid 0.1~0.3% hydroxybenzoate and 99.9~99.7% cosmetic base.
Preferably, the cosmetic base comprises the following raw materials by weight percent:
Preferably, the face mask substrate material is non-woven fabrics, silk fabric, biological fiber, any one in nanofiber.
Preferably, the stimulation includes any one or more feeling in calcination, shouting pain, tight, tingling, itch.
Specifically, subject perceives skin in application facial mask and calcination, shouting pain, tight, tingling, the feeling of itch occurs, And the position for occurring stimulating and stimulation time are recorded, skin sensitivity degree is evaluated with this, specific as follows:
1, sense of discomfort is given a mark
Calcination: insentience 0 is divided;Indistinctly feel 1 point;It is slight to feel 2 points;Medium feeling 3 is divided;It is strong to feel 5 points;
Shouting pain: insentience 0 is divided;Indistinctly feel 1 point;It is slight to feel 2 points;Medium feeling 3 is divided;It is strong to feel 5 points;
Tight: insentience 0 is divided;Indistinctly feel 1 point;It is slight to feel 2 points;Medium feeling 3 is divided;It is strong to feel 5 points;
Tingling: insentience 0 is divided;Indistinctly feel 1 point;It is slight to feel 2 points;Medium feeling 3 is divided;It is strong to feel 5 points;
2, uncomfortable position
Forehead, cheek, wing of nose two sides, eye circumference
3, sensitivity
0 point: insensitive
1-8 points: slight sensitive
9-12 points: slightly sensitive
13-20 points: more sensitive
The utility model has the advantages that
(1) increasingly popularizing recently as skin care concept, facial mask has become one kind indispensable in daily necessities, face The application method of film is simple, is public generally accepted cosmetology mode.Selection facial mask for detect sensitive skin have compared with Good acceptance, and it is easy to carry, and application is convenient, and subject can voluntarily carry out the test of sensitive skin.Also, it is of the invention For detect sensitive skin facial mask can full face application, sensitive part can be more comprehensively evaluated, so that testing result is more Accurately and reliably.
(2) facial mask of the invention is prepared using raw material common in cosmetics, and simplicity is easy to get, and meets " cosmetics safety Technical specification " it requires.Wherein, the common agents in used sensitive detection agent selection cosmetics, additive amount are controlled in human body Acceptable range can not only detect sensitive skin well, filter out sensitive people, and will not cause to damage to skin Wound, is not in the obvious skin symptom such as erythema or wheal in use, has safe and reliable, pervasive advantage that should be good.
Sensitivity detection agent used in facial mask of the invention has the characteristics that as described below:
Phenoxyethanol: Phenoxyethanol (PE) is the common ingredient made up in production process as anticorrosion and bactericidal agent, but simultaneously Phenoxyethanol is also the stimulant to skin.Selection cosmetics often are offseted to have for expense person with raw material Phenoxyethanol and preferably be connect It is spent.In terms of safety, in strict accordance with " cosmetics safety technical specification " related request, controlled concentration limits the use of range 1%, with Guarantee safety of the invention.In the present invention, using Phenoxyethanol as the additive amount preferably 0.01 of sensitive detection agent~ 1.0%.
Lactic acid: lactic acid has good biocompatibility, has effects that wrinkle, skin care, blast, and can also be effectively The pH for adjusting cosmetics, makes it closer to human body, is therefore widely used in skin care item to improve dry skin and cutin Change phenomenon.But lactic acid has certain irritation, is one of the typical stimulus for detecting skin sensitivity.In the present invention, with cream Additive amount preferably 4.0~6.0% of the acid as sensitive detection agent.
Capsaicine: capsaicine is the high-quality natural pigment being present in pimiento, has bright-coloured color, good heat steady Qualitative, safety and reliability can be used as natural pigment addition in cosmetics, while capsaicine has the work of activating vessels With can make of pink and healthy-looking glossy.Although capsaicine is not in cosmetics register, the common raw material being not belonging in cosmetics, But because it is with stronger irritation, by one of the common typical stimulus as detection skin sensitivity.In the present invention, capsicum Element only does test and uses, using capsaicine as the additive amount preferably 0.01~0.03% of sensitive detection agent.
Dodecyl sodium sulfate: dodecyl sodium sulfate (SDS) is common surfactant in cosmetics, with good Good emulsification, infiltration and dispersion performance.However, the SDS of high concentration can rapidly result in the damage of cell membrane, cell occurs bright Aobvious rupture is made into haemolysis, and therefore, SDS is common standard stimulus source in existing stimulation test.In the present invention, with Additive amount preferably 5.0~8.0% of the SDS as sensitive detection agent.
Hydroxybenzoate: hydroxybenzoate, mainly as sterilization antiseptic, can destroy micro- life in cosmetics The cell membrane of object makes intracellular protein denaturation, the antibacterial action with wide spectrum.But hydroxyl is excessively used in cosmetics Benzoic ether can cause contact dermatitis and allergic dermatitis, and regulation hydroxybenzoic acid esters make in " cosmetics health specification " Maximum concentration be 0.4%, in the present invention, using hydroxybenzoate as sensitivity detection agent additive amount preferably 0.1~ 0.3%.
Detailed description of the invention
Fig. 1 is the result on trial of the facial mask of embodiment 1-11.
Specific embodiment
Below with reference to embodiment, the content of the present invention will be explained in more detail.It should be appreciated that implementation of the invention is not limited to In the following examples, the accommodation in any form and/or change made to the present invention fall within the scope of the present invention.
In the present invention, if not refering in particular to, all percentage is weight percent units, all equipment and raw material etc. It is commercially available or the industry is common.If the method that embodiment uses is technology generally in the art without specializing.
Facial mask
For facial mask, the understanding of broad sense should be done, can be the facial mask for capableing of directly application with carrier, or smear The liquid or slurry of formula.It is by the way that facial mask liquid is adsorbed on conduct when facial mask is to be capable of the form of direct application with carrier It is formed on the face mask substrate material of carrier, facial mask liquid is adsorbed on the general technology that the method on face mask substrate material is this field, in this hair In bright, preferably the size of face mask substrate material is 300~350cm2, in single piece facial mask substrate the band liquid measure of facial mask liquid be 17.5~ 22.5g, the band liquid measure of facial mask are 0.05~0.075g/cm2.The place of application of facial mask is not limited only to face, can apply in people Body other positions, such as neck, arm etc..
It is understood that the facial mask liquid for constituting facial mask of the present invention individually can be used as the examination of detection skin sensitivity Its film is used to carry out the detection by agent in face.And facial mask liquid is stored in face mask substrate material and facial mask is made may make Detect more convenient, quick, face mask substrate material can preferably make facial mask liquid be formed in face, will not make facial mask liquid as carrier With face flowing, drippage is intended to, but also applying amount of the facial mask liquid in facial different parts, and in different consumers' faces Applying amount can be controlled in unified range, reduce detection error.
Embodiment 1 is a kind of for detecting the facial mask of sensitive skin
The preparation of facial mask liquid: the component of facial mask liquid is as shown in the table, and xanthan gum adds water liter after first being dispersed with 1,3-BDO For temperature to 80-85 DEG C, stirring and dissolving is uniform, keeps the temperature 15min.B phase is sequentially added after being cooled to 40-45 DEG C, is stirred 15-25 minutes, After turn to stir at low speed be cooled to 30-35 DEG C after discharge.
The preparation of facial mask: facial mask liquid is filling into containing the facial mask bag for folding face mask substrate material, wherein facial mask base used Material is non-woven fabrics, and the area of face mask substrate material is 350 square centimeters, and the amount of pouring into of facial mask liquid is 17.5g.
The facial mask liquid of table 1 using Phenoxyethanol as sensitive detection agent forms
Embodiment 2 is a kind of for detecting the facial mask of sensitive skin
The component of facial mask liquid is as shown in the table, and the preparation of facial mask liquid and facial mask is the same as described in embodiment 1.
The facial mask liquid of table 2 using Phenoxyethanol as sensitive detection agent forms
Embodiment 3 is a kind of for detecting the facial mask of sensitive skin
The component of facial mask liquid is as shown in the table, wherein face mask substrate material used is non-woven fabrics, and the area of face mask substrate material is 300 square centimeters, the amount of pouring into of facial mask liquid is 22.5g, remaining is the same as described in embodiment 1.
The facial mask liquid of table 3 using Phenoxyethanol as sensitive detection agent forms
Embodiment 4 is a kind of for detecting the facial mask of sensitive skin
The component of facial mask liquid is as shown in the table, and the preparation of facial mask liquid and facial mask is the same as described in embodiment 1.
The facial mask liquid of table 4 using lactic acid as sensitive detection agent forms
Embodiment 5 is a kind of for detecting the facial mask of sensitive skin
The component of facial mask liquid is as shown in the table, and the preparation of facial mask liquid and facial mask is the same as described in embodiment 1.
The facial mask liquid of table 5 using lactic acid as sensitive detection agent forms
Embodiment 6 is a kind of for detecting the facial mask of sensitive skin
The component of facial mask liquid is as shown in the table, and the preparation of facial mask liquid and facial mask is the same as described in embodiment 1.
The facial mask liquid of table 6 using lactic acid as sensitive detection agent forms
Embodiment 7 is a kind of for detecting the facial mask of sensitive skin
The component of facial mask liquid is as shown in the table, and the preparation of facial mask liquid and facial mask is the same as described in embodiment 1.
The facial mask liquid of table 7 using capsaicine as sensitive detection agent forms
Embodiment 8 is a kind of for detecting the facial mask of sensitive skin
The component of facial mask liquid is as shown in the table, and the preparation of facial mask liquid and facial mask is the same as described in embodiment 1.
The facial mask liquid of table 8 using SDS as sensitive detection agent forms
Embodiment 9 is a kind of for detecting the facial mask of sensitive skin
The component of facial mask liquid is as shown in the table, and the preparation of facial mask liquid and facial mask is the same as described in embodiment 1.
The facial mask liquid of table 9 using hydroxybenzoate as sensitive detection agent forms
Embodiment 10 is a kind of for detecting the facial mask of sensitive skin
The component of facial mask liquid is as shown in the table, and the preparation of facial mask liquid and facial mask is the same as described in embodiment 1.
The facial mask liquid of table 10 using Phenoxyethanol and lactic acid as sensitive detection agent forms
Embodiment 11 is a kind of for detecting the facial mask of sensitive skin
The component of facial mask liquid is as shown in the table, and the preparation of facial mask liquid and facial mask is the same as described in embodiment 1.
The facial mask liquid of table 11 using Phenoxyethanol and lactic acid as sensitive detection agent forms
The proof test of facial mask prepared by 12 embodiment 1~11 of embodiment
To carrying out using test for the facial mask of embodiment 1-11, while to contain only cosmetic base without sensitive detection agent Facial mask as a control group (component of control group facial mask liquid are as follows: 1,3 butanediol 3.0%, xanthan gum 0.2%, glycerol 2.0%, NaCl 1.0%, water 93.8%).
Select age bracket 25 years old to 40 years old health volunteer 7, all subject's skin of face health are smooth, no erythema, The fash such as furfur, without other dermatopathies or systemic disease.Before test, every subject signs informed consent form, after face cleaning According to usually facial mask being used to get used to tested facial mask, and self-assessment is carried out.Every subject uses a kind of facial mask daily, Face does not use other any skin-protection products during test, and excessive sunlight exposure is avoided during test.Experimental result is such as Shown in Fig. 1.
It can be seen that subject to the excitement of 0.5% lactic acid, 1.0% lactic acid not as good as 0.5% benzene oxygen from the result of Fig. 1 Ethyl alcohol and 1.0% Phenoxyethanol are obvious, illustrate that Phenoxyethanol has stronger irritation compared to lactic acid, are screening sensitive skins The good selection of crowd.The reactivity of 1.0% Phenoxyethanol is 100%, with lower tingling sensation and burning sensation, tested Within the scope of person is sustainable, for more preferred embodiment.
It finds simultaneously, 6.0% lactic acid, 8.0% dodecyl sodium sulfate and 0.1% hydroxybenzoate can be used as quick Sense stimulant is for distinguishing and screening sensitive group;The reactivity of 0.01% capsaicine is 100%, but more sensitive to skin Irritation is larger for crowd, can also be used as sensitive stimulant, but needs its additive amount of strict control.
The sensitive detection agent of two kinds of addition simultaneously in facial mask liquid, such as thorn caused by lactic acid and Phenoxyethanol is added simultaneously Swash larger, tingling sensation and burning sensation are more obvious, also faster, but may generate insufferable shouting pain to sensitive group.
Inventor simultaneously to containing 4.0% lactic acid, 5.0% lactic acid, 0.03% capsaicine, 5% dodecyl sodium sulfate, The facial mask of 7% dodecyl sodium sulfate, 0.2% hydroxybenzoate and 0.3% hydroxybenzoate is tried out, and is obtained Same effect illustrates that the facial mask of the sensitive detection agent containing concentrations above may be incorporated for screening sensitive skin.
Above-mentioned experiment shows containing 0.01%~1.0% Phenoxyethanol or 4.0%~6.0% lactic acid or 0.01%~ The facial mask of 0.03% capsaicine or 5.0%~8.0% neopelex or 0.1~0.3% hydroxybenzoate is equal It can be used in screening sensitive skin, this method has the advantages that safe and reliable, effective, comprehensive.
The foregoing is only a preferred embodiment of the present invention, rather than the embodiment of present invention whole.Above-mentioned implementation Example is not intended to restrict the invention, and for those skilled in the art, the invention may be variously modified and varied.It is all Within the scope of the spirit and principles in the present invention, any modification, equivalent replacement, improvement and so on should be included in guarantor of the invention Within the scope of shield.

Claims (35)

1. Phenoxyethanol is as sensitive detection agent for detecting the purposes in sensitive skin.
2. purposes according to claim 1, which is characterized in that the Phenoxyethanol is included in facial mask.
3. purposes according to claim 2, which is characterized in that the facial mask includes face mask substrate material and facial mask liquid, described Contain by weight percentage 0.01 ~ 1.0% Phenoxyethanol in facial mask liquid.
4. purposes according to claim 3, which is characterized in that also contain by weight percentage 99.0 in the facial mask liquid ~ 99.99% cosmetic base.
5. purposes according to claim 4, which is characterized in that the cosmetic base by following weight percent raw material Composition:
1,3 butanediols 2.0 ~ 4.0%
Xanthan gum 0.1 ~ 0.3%
Glycerol 1.0 ~ 3.0%
NaCl 0.5~2.0%
The water of surplus.
6. purposes described in claim 5, which is characterized in that the preparation method of the facial mask, comprising the following steps:
1) after dispersing xanthan gum with 1,3-BDO plus water is warming up to 80 ~ 85 DEG C, and stirring and dissolving is uniform, keeps the temperature 15min, obtains mixed Close feed liquid;
2) mixed liquor that the step 1) obtains is cooled to after 40 ~ 45 DEG C and sequentially adds Phenoxyethanol, glycerol and NaCl are stirred It mixes 15 ~ 25 minutes, is cooled to 30 ~ 35 DEG C, obtains facial mask liquid;
3) facial mask liquid that the step 2 obtains is stored in face mask substrate material, obtains facial mask.
7. purposes according to claim 6, which is characterized in that face mask substrate material described in the step 3) be non-woven fabrics, Silk fabric, biological fiber, any one in nanofiber.
8. a kind of for detecting the facial mask of sensitive skin, which is characterized in that contain sensitive detection agent in the facial mask.
9. facial mask according to claim 8, which is characterized in that the facial mask includes face mask substrate material and facial mask liquid, described Contain sensitive detection agent in facial mask liquid.
10. facial mask according to claim 9, which is characterized in that the sensitive detection agent contained in the facial mask liquid is benzene oxygen Any one or a few in ethyl alcohol, lactic acid, capsaicine, lauryl sodium sulfate or hydroxybenzoate.
11. facial mask according to claim 10, which is characterized in that when sensitive detection agent is Phenoxyethanol, the facial mask The weight percent of the Phenoxyethanol contained in liquid is 0.01 ~ 1.0%.
12. facial mask according to claim 10, which is characterized in that when sensitive detection agent is lactic acid, in the facial mask liquid The weight percent of the lactic acid contained is 4.0 ~ 6.0%.
13. facial mask according to claim 10, which is characterized in that when sensitive detection agent is capsaicine, the facial mask liquid In the weight percent of capsaicine that contains be 0.01 ~ 0.03%.
14. facial mask according to claim 10, which is characterized in that when sensitive detection agent is dodecyl sodium sulfate, institute The weight percent for stating the dodecyl sodium sulfate contained in facial mask liquid is 5.0 ~ 8.0%.
15. facial mask according to claim 10, which is characterized in that described when sensitive detection agent is hydroxybenzoate The weight percent of the hydroxybenzoate contained in facial mask liquid is 0.1 ~ 0.3%.
16. facial mask according to claim 8, which is characterized in that also contain cosmetic base in the facial mask.
17. facial mask according to claim 16, which is characterized in that the cosmetic base by following weight percent original Material composition:
1,3 butanediols 2.0 ~ 4.0%
Xanthan gum 0.1 ~ 0.3%
Glycerol 1.0 ~ 3.0%
NaCl 0.5~2.0%
The water of surplus.
18. facial mask described in claim 17, which is characterized in that the preparation method of the facial mask, comprising the following steps:
1) after dispersing xanthan gum with 1,3-BDO plus water is warming up to 80 ~ 85 DEG C, and stirring and dissolving is uniform, keeps the temperature 15min, obtains mixed Close feed liquid;
2) mixed liquor that the step 1) obtains is cooled to after 40 ~ 45 DEG C and sequentially adds sensitive detection agent, glycerol and NaCl, Stirring 15 ~ 25 minutes, is cooled to 30 ~ 35 DEG C, obtains facial mask liquid;
3) facial mask liquid that the step 2 obtains is stored in face mask substrate material, obtains facial mask.
19. facial mask according to claim 18, which is characterized in that face mask substrate material described in the step 3) is nonwoven Cloth, silk fabric, biological fiber, any one in nanofiber.
20. a kind of for detecting the facial mask of sensitive skin, including face mask substrate material and facial mask liquid, which is characterized in that every square centimeter Face mask substrate material in contain 0.005 ~ 0.75mg Phenoxyethanol.
21. facial mask according to claim 20, which is characterized in that in face mask substrate material every square centimeter also containing 49.5 ~ 74.9925mg cosmetic base.
22. facial mask according to claim 21, which is characterized in that the cosmetic base by following weight percent original Material composition:
1,3 butanediols 2.0 ~ 4.0%
Xanthan gum 0.1 ~ 0.3%
Glycerol 1.0 ~ 3.0%
NaCl 0.5~2.0%
The water of surplus.
23. facial mask according to claim 22, which is characterized in that the preparation method of the facial mask, comprising the following steps:
1) after dispersing xanthan gum with 1,3-BDO plus water is warming up to 80 ~ 85 DEG C, and stirring and dissolving is uniform, keeps the temperature 15min, obtains mixed Close feed liquid;
2) mixed liquor that the step 1) obtains is cooled to after 40 ~ 45 DEG C and sequentially adds Phenoxyethanol, glycerol and NaCl are stirred It mixes 15 ~ 25 minutes, after being cooled to 30 ~ 35 DEG C, obtains facial mask liquid;
3) facial mask liquid that the step 2 obtains is stored in face mask substrate material, obtains facial mask.
24. facial mask according to claim 23, which is characterized in that face mask substrate material described in the step 3) is nonwoven Cloth, silk fabric, biological fiber, any one in nanofiber.
25. a kind of method using facial mask detection sensitive skin, which comprises the steps of:
1) it prepares a kind of for detecting the facial mask of sensitive skin, sensitive detection agent is contained in the facial mask;
2) facial mask prepared by step 1) is spread on into human skin, perception is with the presence or absence of stimulation;
3) it stimulates if it exists, records stimulation location and stimulation time, evaluate skin sensitivity degree.
26. according to the method for claim 25, which is characterized in that the facial mask in the step 1) includes face mask substrate material and face Film liquid, wherein contain cosmetic base and sensitive detection agent in the facial mask liquid.
27. according to the method for claim 26, which is characterized in that the sensitive detection agent contained in the facial mask liquid is benzene oxygen Any one or a few in ethyl alcohol, lactic acid, capsaicine, lauryl sodium sulfate and hydroxybenzoate.
28. according to the method for claim 27, which is characterized in that when sensitive detection agent is Phenoxyethanol, the facial mask Contain by weight percentage 0.01 ~ 1.0% Phenoxyethanol and 99.0 ~ 99.99% cosmetic base in liquid.
29. according to the method for claim 27, which is characterized in that when sensitive detection agent is lactic acid, in the facial mask liquid Contain by weight percentage 4.0 ~ 6.0% lactic acid and 94.0 ~ 96.0% cosmetic base.
30. according to the method for claim 27, which is characterized in that when sensitive detection agent is capsaicine, the facial mask liquid In contain by weight percentage 0.01 ~ 0.03% capsaicine and 99.97 ~ 99.99% cosmetic base.
31. according to the method for claim 27, which is characterized in that when sensitive detection agent is dodecyl sodium sulfate, institute It states and contains by weight percentage 5.0 ~ 8.0% dodecyl sodium sulfate and 92.0 ~ 95.0% cosmetic base in facial mask liquid.
32. according to the method for claim 27, which is characterized in that described when sensitive detection agent is hydroxybenzoate Contain by weight percentage 0.1 ~ 0.3% hydroxybenzoate and 99.9 ~ 99.7% cosmetic base in facial mask liquid.
33. according to the described in any item methods of claim 28 ~ 32, which is characterized in that the cosmetic base is by following weight The raw material of percentage forms:
1,3 butanediols 2.0 ~ 4.0%
Xanthan gum 0.1 ~ 0.3%
Glycerol 1.0 ~ 3.0%
NaCl 0.5~2.0%
The water of surplus.
34. according to the method for claim 26, which is characterized in that the face mask substrate material is non-woven fabrics, silk fabric, biology Any one in fiber, nanofiber.
35. according to the method for claim 25, which is characterized in that the stimulation includes calcination, shouting pain, tight, tingling, scabies Any one or more feeling in itching.
CN201910199360.1A 2019-03-15 2019-03-15 A kind of facial mask and its application for detecting sensitive skin Pending CN109966512A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910199360.1A CN109966512A (en) 2019-03-15 2019-03-15 A kind of facial mask and its application for detecting sensitive skin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910199360.1A CN109966512A (en) 2019-03-15 2019-03-15 A kind of facial mask and its application for detecting sensitive skin

Publications (1)

Publication Number Publication Date
CN109966512A true CN109966512A (en) 2019-07-05

Family

ID=67079113

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910199360.1A Pending CN109966512A (en) 2019-03-15 2019-03-15 A kind of facial mask and its application for detecting sensitive skin

Country Status (1)

Country Link
CN (1) CN109966512A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111991254A (en) * 2020-08-12 2020-11-27 暨南大学 Halloysite mud mask and preparation method thereof
WO2021000631A1 (en) * 2019-03-15 2021-01-07 上海中翊日化有限公司 Evaluation method for allergy-soothing substance for cosmetics
CN113181531A (en) * 2021-04-26 2021-07-30 上海应用技术大学 Human body healthy skin irritation model and establishment method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003063817A1 (en) * 2002-01-28 2003-08-07 Lectec Corporation Cosmetic patch
CN108186394A (en) * 2018-03-14 2018-06-22 广东德丝肤生物科技有限公司 Facial mask essence and preparation method are nourished in a kind of Shu Min maintenances
CN108272672A (en) * 2018-03-13 2018-07-13 北京东方淼森生物科技有限公司 A kind of Chinese medicine composition for alleviating epoxy ethanol and polyalcohol stimulation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003063817A1 (en) * 2002-01-28 2003-08-07 Lectec Corporation Cosmetic patch
CN108272672A (en) * 2018-03-13 2018-07-13 北京东方淼森生物科技有限公司 A kind of Chinese medicine composition for alleviating epoxy ethanol and polyalcohol stimulation
CN108186394A (en) * 2018-03-14 2018-06-22 广东德丝肤生物科技有限公司 Facial mask essence and preparation method are nourished in a kind of Shu Min maintenances

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
于惠青 编著: "《女性美容面面观》", 31 August 2016, 复旦大学出版社 *
周琼 等: ""功能性护理品用新型保湿防腐剂烷基邻位二醇"", 《广州化工》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021000631A1 (en) * 2019-03-15 2021-01-07 上海中翊日化有限公司 Evaluation method for allergy-soothing substance for cosmetics
CN111991254A (en) * 2020-08-12 2020-11-27 暨南大学 Halloysite mud mask and preparation method thereof
CN111991254B (en) * 2020-08-12 2023-06-09 暨南大学 Halloysite mud mask and preparation method thereof
CN113181531A (en) * 2021-04-26 2021-07-30 上海应用技术大学 Human body healthy skin irritation model and establishment method thereof

Similar Documents

Publication Publication Date Title
Draelos et al. Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea
CN101180030B (en) Skin cosmetic and wrinkle-reducing agent
CN109966512A (en) A kind of facial mask and its application for detecting sensitive skin
JP6554540B2 (en) Composition for treating skin conditions
WO2021000631A1 (en) Evaluation method for allergy-soothing substance for cosmetics
JP2018515485A (en) Method for improving the appearance of the skin and compositions therefor using nicotinamide riboside
CN111671673A (en) Long-acting makeup holding powder base solution and preparation method thereof
KR102140198B1 (en) How to improve the appearance of abnormal discoloration around the orbit
CN107115220A (en) A kind of activity of fighting against senium compositions and preparation method and application
WO2018193565A1 (en) Method for evaluating impact of test substance or product on skin
JP2022550759A (en) Compositions and their use in the preparation of products for the care of the skin of night owls
JP6674042B2 (en) Cosmetic composition comprising VICIA FABA for ameliorating periorbital pigmentation
JP2007008912A (en) Method of cosmetic treatment for maintaining homeostasis of rhythm of life
CN109316380A (en) A kind of fullerene is luxurious to dote on washing cream
CN107095804A (en) A kind of tea seed extraction oil skin cream and preparation method thereof
CN102860975A (en) Skin-whitening and moisture-preserving skin-care product for eyes and preparation method for skin-whitening and moisture-preserving skin-care product
Chandrashekar et al. Effectiveness and safety of topical under-eye serum in patients with periorbital hyperpigmentation: An open-label single arm prospective study
CN109069882A (en) Improve the method for the appearance of periorbit pigment anomaly
CN109069406A (en) Improve the method for the appearance of periorbit pigment anomaly
AL Mohsen et al. Trichoscopic clues for diagnosis of patchy scalp alopecia in the Egyptian patients
Farage et al. Sensitive skin: intrinsic and extrinsic contributors
Dashore et al. Assessment of efficacy of six different moisturizing creams in maintaining the hydration of skin in healthy human volunteers: A randomized controlled study
Chirikhina Human face mapping based on TEWL, hydration and ultrasound
Sarmento Improving Skin Conductivity to Small Ions for Enhanced Biosignal Monitoring
Kartini et al. The Effect of Giving Black Rice Extract Ointment (Oryza Sativa L. Indica) on the Growth of Wistar Rat (Rattus Novergicus) Hair Follicles

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20190705

RJ01 Rejection of invention patent application after publication