CN109908452A - A kind of bladder Tiny ecosystem Acquisition Instrument - Google Patents

A kind of bladder Tiny ecosystem Acquisition Instrument Download PDF

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Publication number
CN109908452A
CN109908452A CN201811318780.9A CN201811318780A CN109908452A CN 109908452 A CN109908452 A CN 109908452A CN 201811318780 A CN201811318780 A CN 201811318780A CN 109908452 A CN109908452 A CN 109908452A
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CN
China
Prior art keywords
catheter
bladder
inner catheter
tiny ecosystem
steel wire
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811318780.9A
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Chinese (zh)
Inventor
冯宁翰
柳丰萍
冯杨焜
杨承健
董坚
郝爱民
汪洋
徐新宇
吴云鸿
涂小妹
杨宪法
徐锡凤
吴岩
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Wuxi No 2 Peoples Hospital
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Wuxi No 2 Peoples Hospital
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Priority to CN201811318780.9A priority Critical patent/CN109908452A/en
Publication of CN109908452A publication Critical patent/CN109908452A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a kind of bladder Tiny ecosystem Acquisition Instruments, including outer catheter, inner catheter, pusher and adapter;Inner catheter is set in outer catheter, pusher is connect with inner catheter, inner catheter is moved forward along outer catheter inner wall, the connection of the other end of adapter and inner catheter is for conveying from the acquisition object that inner catheter obtains to external container, pusher driving extends forwardly into bladder, and observes catheter by camera and judge whether catheter arrived neck of urinary bladder by chemistry and the detection signal of humidity sensor generation.When catheter inserting to neck of urinary bladder, operator presses inner catheter pusher, inner catheter is pushed to bladder at this time, and outer catheter then stays at neck of urinary bladder, therefore can guarantee that, when conduit is inserted into bladder, only inner catheter enters bladder, and it is adhered to the microorganism of outer catheter and thimerosal not can enter bladder then, to prevent bladder Tiny ecosystem to be affected, guarantee the accuracy of Tiny ecosystem testing result, diagnoses the illness for clinician and accurately data are provided.

Description

A kind of bladder Tiny ecosystem Acquisition Instrument
Technical field
The present invention relates to medical auxiliary apparatus technical field, especially a kind of bladder Tiny ecosystem Acquisition Instrument.
Background technique
Researcher needs to use urine tester when carrying out the inspection of bladder urine Tiny ecosystem to patient.Currently grind Study carefully personnel and mainly use following several methods: 1. suprapubic puncture art: the urine specimen that this method obtains can represent completely Bladder Tiny ecosystem.But this method needs to puncture into bladder acquisition urine through peritonaeum using bladder trocar, it is postoperative to may occur in which The complication such as cystirrhagia, notch leakage of urine, so that unnecessary pain is caused to patient, therefore, it is difficult to be audited by ethics, and Obtain the informed consent of patient.2. catheterization: advantage is to adverse reaction caused by patient and pain compared with suprapubic puncture Art is small, and urine specimen is comparable to be truly reflected bladder Tiny ecosystem.However, it comes with some shortcomings, for example, due to urethral catheterization It is preoperative to need disinfecting perineum and urethral orifice, thus the thimerosal for remaining on urethral orifice would be possible to bring with the insertion of catheter to Bladder, these thimerosals may kill some bladder microorganisms, thus influence testing result.In addition, due to catheter be by Urethra is inserted into bladder, parasitizes the microbes of urethra as catheter brings bladder into, this also will affect bladder Tiny ecosystem Testing result.3. Urine culture sample: being to acquire the mud-stream urine of patient after sterilization as the mark for detecting bladder Tiny ecosystem This;Advantage: hurtless measure, patient are acceptant;Disadvantage: studies have shown that it can not really reflect bladder Tiny ecosystem, wherein containing Compared with the microorganism mostly from anus, perineum and vagina.4. directly urinating: advantage: hurtless measure, patient are acceptant;Disadvantage: The microbial contamination from anus, perineum and vagina is more vulnerable to compared with Urine culture sample.
In conclusion to understand the true Tiny ecosystem of bladder, during researcher need to ensure collection of specimens, urine specimen is not By the pollution from anus, vagina, perineal skin microorganism.Meanwhile it should also be avoided thimerosal to bladder microorganism It destroys.
Summary of the invention
The purpose of the present invention is to propose to a kind of bladder Tiny ecosystem Acquisition Instruments;The device can prevent urine specimen to be contaminated.
The purpose of the present invention is achieved through the following technical solutions:
Bladder Tiny ecosystem Acquisition Instrument provided by the invention, including outer catheter, inner catheter, pusher and adapter;In described Conduit is set in outer catheter, and the pusher is connect with inner catheter, for making inner catheter along outer under the action of motive force Pipe inner wall moves forward, the other end connection of the adapter and inner catheter for convey from the acquisition object of inner catheter acquisition to External container.
Further, be provided on the outer catheter for observe outer catheter in operation the location of status signal can Viewing system, the visible system include camera and visualizer;The camera lens is set to outer catheter and is located at inner catheter forward movement One end;The camera is for obtaining outer catheter location status signal in operation;The camera and visualizer Connection;The position state signal is transferred to the position that visualizer judges outer catheter for operator.
Further, the adapter is attached on inner catheter, is provided on the adapter and collection of specimens centrifuge tube phase Matched screw thread.
Further, the outer catheter is provided with sealing ring, and the sealing ring is set to two layers of conduit of inner catheter and outer catheter Between.
Further, the pusher includes driving device and a steel wire for being set to inner catheter, and one of the steel wire Be embedded in the head end of inner catheter, the other end is located at the collar extension of inner catheter, to collar extension at expose, and connect driving device;Work as behaviour When author pins driving device, steel wire pushes inner catheter to move forward.
Further, it is mushroom umbrella-shaped structure that the steel wire, which is embedded in the part of inner catheter head end,
Further, helicitic texture is provided on the steel wire, the inner catheter is provided with and the matched steel wire of helicitic texture Pipe.
Further, the driving device uses powered actuator, the powered actuator include fixed bracket, extruding wheel, Driving wheel, wired hole and handle;The extruding wheel is set on fixed bracket with driving wheel by parallel wheel shaft, the extruding Wired hole is set between wheel and driving wheel, and the wired hole is for fixing steel wire, so that steel wire is generated in the rotation of driving wheel The effect of frictional force pushes steel wire to move forward forward, and the diameter in the wired hole is matched with gauge of wire.
Further, the front end of the outer catheter is additionally provided with chemical sensor, when the chemical sensor touches urine In urea after issue detection signal, the detection signal is transferred to the signal receiver for being set to catheter outer end, the letter Number receiver is connect with visualizer, and passes through visualizer display detection signal.
Further, the front end of the outer catheter is additionally provided with humidity sensor, when the humidity sensor touches urine In aqueous after issue detection signal, the detection signal is transferred to the signal receiver for being set to catheter outer end, the letter Number receiver is connect with visualizer, and passes through visualizer display detection signal.
By adopting the above-described technical solution, the present invention has the advantage that:
Bladder Tiny ecosystem Acquisition Instrument provided by the invention constitutes catheter using outer catheter and inner catheter;Then pass through promotion Device driving inner catheter extends forwardly into bladder, and observes whether catheter arrived bladder by the camera in the visible system Neck, when catheter inserting to neck of urinary bladder, operator presses inner catheter pusher, and inner catheter is pushed to bladder at this time, and outer catheter Then stay at neck of urinary bladder.Therefore, the microorganism and thimerosal for being adhered to outer catheter not can enter bladder then, to prevent bladder Tiny ecosystem is affected.The device can prevent urine and urethral secretions, prostatic fluid from flowing to and leading after entering between two layers of conduit Pipe, that is, prevent urine specimen by the pollution of these pollutants.When inner catheter is to when extension at bladder, this sealing ring can be therewith It extends internally.
Further advantage, target and feature of the invention will be illustrated in the following description to a certain extent, and And to a certain extent, based on will be apparent to those skilled in the art to investigating hereafter, Huo Zheke To take a hint from the practice of the present invention.The objects and other advantages of the present invention can be realized by following specification and It obtains.
Detailed description of the invention
Detailed description of the invention of the invention is as follows.
Fig. 1 is the structural schematic diagram of bladder Tiny ecosystem Acquisition Instrument of the present invention.
Fig. 2 is the structural schematic diagram of inventive drive means.
In figure: 1 be outer catheter, 2 be inner catheter, 3 be pusher, 4 be adapter, 5 be sealing ring, 31 be driving device, 32 it is steel wire, 33 is steel wire tube;61 it is camera, 62 is visualizer;311 it is fixed bracket, 312 be extruding wheel, 313 is actively Wheel, 314 be wheel shaft, 315 be wired hole, 316 be handle;
71 it is chemical sensor, 72 is humidity sensor.
Specific embodiment
Present invention will be further explained below with reference to the attached drawings and examples.
As shown, bladder Tiny ecosystem Acquisition Instrument provided in this embodiment, including visible system, inner catheter, outer catheter, push away Dynamic device, adapter and sealing ring;Guang Tiny ecosystem collection of specimens instrument provided in this embodiment includes that outer catheter and inner catheter are constituted Catheter.Catheter is inserted into bladder from urethral orifice by routine disinfection perineum and urethral orifice before collect specimen, by can when insertion Observe whether catheter arrived at neck of urinary bladder at camera lens in viewing system, when conduit is inserted at neck of urinary bladder, operator's pressing The pusher of inner catheter, inner catheter is pushed in bladder at this time, and outer catheter then stays at neck of urinary bladder.Therefore, it is adhered to outer The microorganism of conduit and thimerosal not can enter bladder then, so that bladder Tiny ecosystem be prevented to be affected.
Catheter provided in this embodiment includes inner catheter and outer catheter, and two layers of conduit is inside and outside overlay structure;Outer catheter Front end is embedded with the camera whether being inserted at neck of urinary bladder for observing conduit, and inner catheter is by there is the silica gel of fold to be made It is extendible.When outer catheter reaches at neck of urinary bladder, operator presses inner catheter pusher, and inner catheter may extend in bladder and adopt Collect urine.The secretion in conduit or prostatic fluid enter inside and outside catheter interstitial heel row to collection of specimens pipe, collar extension in order to prevent Interior outer catheter between have sealing ring.
When specific operation, operator can observe whether conduit reaches wing by being mounted on the camera of outer catheter head end At Guang neck, if it is observed that arrived at neck of urinary bladder, operator pins inner catheter push key at this time, and inner catheter is sent to bladder and is taken Urine, outer catheter then only stay at neck of urinary bladder, without entering bladder.Accordingly it is possible to prevent because outer catheter is inserted into cathing process In be adhered to the bacterium of outer catheter outer layer and bring bladder into.
Camera in visible system provided in this embodiment is transmitted by the signal that optic delivery pipe obtains camera To visualizer, judge whether conduit has been inserted at neck of urinary bladder for operator.
Pusher provided in this embodiment includes driving device, steel wire, power supply and switch;Power supply and switch are set to entirely At the visualizer of device;Driving device can use motor and catch bar, be connected to motor after power supply and switch connection, motor is logical Catch bar to be crossed to connect with steel wire, driving catch bar travels forward when the motor rotates, and catch bar drives steel wire to move forward, from And generate the active force for pushing inner catheter to move forward;Steel wire provided in this embodiment is the micro-fine steel embedded in inner catheter tube wall Silk;One of steel wire is embedded in the head end of inner catheter, is not directly exposed to outside conduit.The other end of steel wire is located at inner catheter Collar extension, and to exposing 3cm at collar extension, top is connected with inner catheter pusher;Junction is using similar between steel wire and inner catheter In mushroom umbrella-shaped structure, the front end of conduit is inserted broken when can push forward to avoid inner catheter in this way.There is electricity on pusher Source and switch two-part structure, after operator pins power switch, steel wire is moved forward, to bring inner catheter into bladder.
Since the tissue color of the urethra internal sphincter of bladder neck outer end is close with close to the urethral tissue color of outer end, For the doctor or nurse of no urological surgery experience, possibly the image that can not be transmitted from camera judge catheter Whether head end has been inserted to neck of urinary bladder, therefore, this bladder Tiny ecosystem acquisition system also including, the Front-end Design of outer catheter chemistry and Humidity sensor.Chemical sensor can issue signal to the signal reception for being located at catheter outer end after touching the urea in urine Device.Chemical sensor is made of using methyl ethylene ether polymer, and enzymatic can occurs in it after touching the urea in urine Reaction.Enzymatic reaction can generate electrochemical signals after occurring, and signal can be conducted to the signal receiver of catheter outer end.Work as urine In urea with urase in chemical sensor is stored and phosphate buffer mixes when, carry out urase enzymatic reaction, then Fluorescence reaction is further carried out with para hydroxybenzene propionic acid, hydrogen peroxide, nano oxidized copper solution and phosphate buffer, it is described to take the photograph As head obtains the fluorescence intensity of fluorescence reaction product;It is transferred in visualizer.
Meanwhile humidity sensor touches the signal that can also issue signal to catheter outer end after moisture (i.e. urine) and receives Device.So this system can prompt whether operator's catheter front end arrived bladder neck there are three signal, i.e., video is believed Number, chemical sensitisation signal and humidity sensor signal.Therefore, it is ensured that when conduit is inserted into bladder, only inner catheter enters bladder, and The microorganism and thimerosal for being adhered to outer catheter not can enter bladder then, so that bladder Tiny ecosystem be prevented to be affected, guarantee micro- The accuracy of ecological testing result diagnoses the illness for clinician and provides accurately data.
Moisture sensor provided in this embodiment uses lithium chloride humistor, and the lithium chloride humistor is to utilize suction Moist salt deliquesces, and ionic conductivity changes and manufactured hygrometric element;The hygrometric element includes lead, substrate, sense Wet layer and electrode;Lithium chloride usually forms mixture with polyvinyl alcohol, and in lithium chloride (LiCl) solution, Li and Cl are with positive and negative The form of ion exists, and Li+Strong to the attraction of hydrone, ionic hydration degree is high, the ion conductivity in solution It is directly proportional to concentration.When solution is placed in certain warm and humid field, if envionmental humidity is high, solution will absorb moisture, drop concentration Low, therefore, solution resistance rate increases.Otherwise when envionmental humidity is lower, then solution concentration increases, resistivity decline, To realize the measurement to humidity.
Moisture sensor provided in this embodiment forms urine signal acquisition circuit, the wet sensitive by resistance and triode One end of sensor is connected with the cathode of power supply, and the other end is connected by resistance with the base stage of triode;The collection of triode The anode of electrode and diode connects, and the cathode of diode and the input terminal of single-chip microcontroller connect, while the cathode of diode passes through The connection of the cathode of resistance and power supply;The output end of the single-chip microcontroller is connect with visualizer.
Triode provided in this embodiment uses the triode of model 8550PNP.
Driving device provided in this embodiment can also use powered actuator, and the powered actuator includes fixed branch Frame, extruding wheel, driving wheel, wired hole and handle;The extruding wheel is set to fixed bracket by parallel wheel shaft with driving wheel On, wired hole is set between the extruding wheel and driving wheel, the wired hole for fixing steel wire, the diameter in the wired hole with Gauge of wire matching can generate the collective effect of chucking power and the frictional force generated when driving wheel rotates to steel wire Under, continual forward movement steel wire is additionally provided with frictional layer inside the wired hole, and the frictional layer is for increasing and steel wire Between frictional force.Extruding wheel provided in this embodiment, driving wheel use the idler wheel of cylindrical body.
When specific operation, when operator observes that conduit has been inserted at neck of urinary bladder, inner catheter can be pressed and pushed away Dynamic device, makes inner catheter be inserted into bladder, when operator pins inner catheter pusher, fine steel wire can guide inner catheter to be inserted to wing Guang.
The adapter provided in this embodiment for being used to connect urine collection tube: the adapter is attached to inner catheter, above has and marks The screw thread that this acquisition centrifuge tube matches.Before conduit insertion, the sterile centrifugation tube of collect specimen is threaded to be connected by operator On device.It, can chamber pot after conduit insertion.
The sealing ring provided in this embodiment being set between inner catheter and outer catheter, using contractile silica gel system At can prevent urine and urethral secretions, prostatic fluid from flowing to inner catheter after entering between two layers of conduit, that is, prevent urine specimen Pollution by these pollutants.When inner catheter is to when extension at bladder, this sealing ring can extend therewith.
Inner catheter and outer catheter provided in this embodiment are made of macromolecule polypropylene material.
Finally, it is stated that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although referring to compared with Good embodiment describes the invention in detail, those skilled in the art should understand that, it can be to skill of the invention Art scheme is modified or replaced equivalently, and without departing from the objective and range of the technical program, should all be covered in the present invention Protection scope in.

Claims (9)

1. a kind of bladder Tiny ecosystem Acquisition Instrument, it is characterised in that: including outer catheter, inner catheter, pusher and adapter;In described Conduit is set in outer catheter, and the pusher is connect with inner catheter, for making inner catheter along outer under the action of motive force Pipe inner wall moves forward, and the other end of the adapter and inner catheter connects, for conveying the acquisition object obtained from inner catheter To external container.
2. bladder Tiny ecosystem Acquisition Instrument as described in claim 1, it is characterised in that: be provided on the outer catheter for observing The visible system of outer catheter location status signal in operation, the visible system includes camera and visualizer;Institute It states camera lens and is set to one end that outer catheter is located at inner catheter forward movement;The camera is for obtaining outer catheter institute in operation The position state signal at place;The camera is connect with visualizer;The position state signal is transferred to visualizer for operator Judge the position of outer catheter.
3. bladder Tiny ecosystem Acquisition Instrument as described in claim 1, it is characterised in that: the adapter is attached on inner catheter, The screw thread to match with collection of specimens centrifuge tube is provided on the adapter.
4. bladder Tiny ecosystem Acquisition Instrument as described in claim 1, it is characterised in that: the outer catheter is provided with sealing ring, institute Sealing ring is stated to be set between two layers of conduit of inner catheter and outer catheter.
5. bladder Tiny ecosystem Acquisition Instrument as described in claim 1, it is characterised in that: the pusher includes driving device and sets It is placed in a steel wire of inner catheter, one of the steel wire is embedded in the head end of inner catheter, and the other end is located at the outer of inner catheter Mouthful, to collar extension at expose, and connect driving device;When operator pins driving device, steel wire pushes inner catheter to move forward.
6. bladder Tiny ecosystem Acquisition Instrument as described in claim 1, it is characterised in that: the steel wire is embedded in inner catheter head end Part is mushroom umbrella-shaped structure, and there are chemical sensor and humidity sensor in the nearly bladder end of umbrella-shaped structure.
7. bladder Tiny ecosystem Acquisition Instrument as described in claim 1, it is characterised in that: it is provided with helicitic texture on the steel wire, The inner catheter is provided with and the matched steel wire tube of helicitic texture.
8. bladder Tiny ecosystem Acquisition Instrument as claimed in claim 5, it is characterised in that: the driving device uses manual actuation Device, the powered actuator include fixed bracket, extruding wheel, driving wheel, wired hole and handle;The extruding wheel and driving wheel are logical It crosses parallel wheel shaft to be set on fixed bracket, wired hole is set between the extruding wheel and driving wheel, the wired hole is used for Fixed steel wire, so that steel wire pushes steel wire to move forward under the action of generating frictional force in the rotation of driving wheel, it is described wired The diameter in hole is matched with gauge of wire.
9. bladder Tiny ecosystem Acquisition Instrument as described in claim 1, it is characterised in that: the front end of the outer catheter is additionally provided with wet Sensor is spent, detection signal is issued after the humidity sensor touches the aqueous in urine, the detection signal is transferred to It is set to the signal receiver of catheter outer end, the signal receiver is connect with visualizer, and is shown and detected by visualizer Signal.
CN201811318780.9A 2018-11-07 2018-11-07 A kind of bladder Tiny ecosystem Acquisition Instrument Pending CN109908452A (en)

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Publication number Priority date Publication date Assignee Title
CN110464384A (en) * 2019-07-11 2019-11-19 江南大学 A kind of renal plevis urine Tiny ecosystem collection of specimens and pollution verification method
CN113769236A (en) * 2021-07-30 2021-12-10 青岛大学附属医院 A intervene pipe auxiliary device for emergency nursing
CN114403937A (en) * 2022-03-31 2022-04-29 杭州谷禾信息技术有限公司 Anti-pollution urine microecological specimen collection device

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CN114403937A (en) * 2022-03-31 2022-04-29 杭州谷禾信息技术有限公司 Anti-pollution urine microecological specimen collection device

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