CN109908376A - A kind of application of LED ultraviolet lamp source in photochemical method blood inactivation treatment equipment - Google Patents
A kind of application of LED ultraviolet lamp source in photochemical method blood inactivation treatment equipment Download PDFInfo
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- CN109908376A CN109908376A CN201910152244.4A CN201910152244A CN109908376A CN 109908376 A CN109908376 A CN 109908376A CN 201910152244 A CN201910152244 A CN 201910152244A CN 109908376 A CN109908376 A CN 109908376A
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Abstract
The invention discloses a kind of application of LED ultraviolet lamp source in photochemical method blood inactivation treatment equipment, can be applied to methylenum careuleum/visible-light treatment method, psoralen/UVA facture, riboflavin/UV facture.The fully automatic blood inactivation treatment equipment with LED ultraviolet source that the present invention also provides a kind of, including outer cabinet, specimen holder, blood vessel, the ultraviolet lamp plate of LED, the outer cabinet front is equipped with control panel and sample port, and the top or bottom of the specimen holder or blood solution is arranged in the ultraviolet lamp plate of LED；Several samples flexible disk is set on the specimen holder, and the flexible disk of the sample can stretch out or retract the sample port；The blood vessel is bag-shaped or tubulose, and blood is static or flowable state in container.Equipment provided by the invention uses full-automatic control system, can actively adjust the ultraviolet emission intensity of LED ultraviolet lamp, can increase exposure intensity, to greatly shorten the processing time, improves treatment effeciency, it can be achieved that scale or miniaturization processing.
Description
Technical field
The present invention relates to field of medical device, in particular to a kind of LED ultraviolet lamp source is in photochemical method blood inactivation treatment
Application in equipment.
Background technique
With the continuous development of medical technology, treatment of blood transfusion has become the common medical procedure of modern medicine, such as surgery
Operation needs massive transfusion operation etc..However, blood is the culture medium of good bacterium and virus, especially various viral livers
The viruses such as inflammation, AIDS, are widely present in blood, if dealing with improperly, blood will become pathophorous medium.Therefore, lead to
It is even more troubling to cross the disease propagated using blood product.
Ensure that the main method of blood product safety is pathogen inactivated.Bloodborne pathogens inactivation refers to through physics or change
Learning to do section destroys the structure of virus protein or viral nucleic acid, and virus that may be present in blood is allowed to lose infection, cause a disease
And fertility.The common method of blood inactivation technology have pasteurization, organic solvent/stain release mix (S/D) method,
Membrane filter method, methylene blue photochemical, psoralen photochemical method, riboflavin photochemical method etc..Wherein, methylene blue method is at home
Using relatively wide, this method requires methylenum careuleum to reach enough dosages, can serge blue there is residual toxicity, plasma protein damage that treated
It loses larger.Riboflavin photochemical method is novel safer pathogen inactivated method, and there is inactivation to compose wide, additive safety
Etc. characteristics, application prospect it is more preferable.
Patent CN201621426483.2 discloses a kind of ultraviolet inactivation system based on dual wavelength, including rack, sample introduction
Module draws basket support and draws basket, draws basket support to connect with rack, draws first for being provided with and drawing basket support glide direction perpendicular in basket support
Guiding axis and with orthogonal second guiding axis of the first guiding axis；It draws and is provided with first bearing in basket, basket is drawn to pass through first axle
It holds and is slidably connected with the realization of the first guiding axis, shake up module and be connected with the second guiding axis；The upper and lower of basket is drawn to be respectively provided with ultraviolet lamp
Group, power module are arranged in bottom of the frame.The patent solves conventional pouch by using the design of upper and lower two kinds of ultraviolet lightings
Blood product inactivates equipment and inactivates halfway defect, so that riboflavin is had an effect pathogen to greatest extent, reaches inactivation
The purpose of sterilization.
Patent CN201220508130.2 discloses a kind of plaque virus inactivating device, including supporting network and ultraviolet lamp,
Ultraviolet lamp is divided into upper layer and lower layer, and supporting network is between upper and lower ultraviolet lamp, and the distance between ultraviolet lamp and supporting network are adjustable, purple
Outer lamp includes lamp box, fluorescent tube and barn door, can control irradiating ultraviolet light line intensity and time by adjusting barn door；It uses
When, blood bag is placed on supporting network, bilevel ultraviolet lamp is opened, ultraviolet light uniform irradiation is killed in blood bag upper and lower surface
Virus in blood.The device can have no adverse reaction to human body, securely and reliably with riboflavin use in conjunction.
Patent CN201610070102.X discloses a kind for the treatment of of blood products system based on riboflavin photochemical method, packet
It includes cabinet and blood bag, is equipped with ultraviolet lamp, lighting process bag pallet in cabinet up and down, blood bag includes that blood enters pipe, at illumination
Manage bag, riboflavin added volume and finished bag.The system can effectively inactivate all kinds of pathogen and lymphocyte, after inactivation treatment
Removal additive is not needed, while increasing constant temperature system, it is easy to operate, it is highly-safe.
However, the ultraviolet source at present using the blood inactivation equipment of photochemical method is in the form of a single, use common glimmering
The UV intensity of light ultraviolet lamp tube, light source transmitting is smaller, can not achieve the big intensity ultraviolet light of transmitting, causes blood processing time
Longer, treating capacity is less.In addition, the size length specification of common uv lamp is more single, utilization rate is lower, is unable to satisfy blood
Inactivate the customization requirement of scale or the miniaturization of equipment.
Summary of the invention
In order to overcome the deficiencies of the prior art, the present invention provides a kind of LED ultraviolet lamp sources at photochemical method blood inactivation
Manage the application in equipment.
Array is placed with the ultraviolet lamp group of LED of transmitting different wave length, the LED ultraviolet lamp in the LED ultraviolet lamp source
The circuit configuration of group controls ultraviolet lamp extinguishing in the two sides and the back side of the LED ultraviolet lamp source by way of controlling electric current
Number and/or ultraviolet lamp brightness.
The line number and columns of the LED ultraviolet lamp array arrangement are 4-10, it is preferred that the LED ultraviolet lamp array arrangement
Line number and columns be 6-8, it is furthermore preferred that the line number of the LED ultraviolet lamp array arrangement and columns are 6,7,8.
Installation site of the LED ultraviolet lamp source in the photochemical method blood inactivation treatment equipment is blood vessel
One or several combinations at top, bottom, side, centre.
The ablation method that the photochemical method blood inactivation treatment equipment uses is selected from methylenum careuleum/visible-light treatment method, mends
Bone fat element/UVA facture and riboflavin/UV facture.
The fully automatic blood inactivation treatment equipment with LED ultraviolet source that the present invention also provides a kind of, the equipment tool
There are full-automatic control system and New LED ultraviolet lamp source, the UV intensity of the ultraviolet lamp source is adjustable, the row of the ultraviolet lamp
Mode for cloth can satisfy miniaturization or scale blood inactivation demand.
It is set the technical scheme adopted by the invention is that providing a kind of fully automatic blood inactivation treatment with LED ultraviolet source
Standby, including the ultraviolet lamp plate of outer cabinet, specimen holder, blood vessel, LED, the outer cabinet front is equipped with control panel and sample port,
The control panel is equipped with UV intensity regulation button, and the setting specimen holder and the ultraviolet lamp plate of LED, described in the outer cabinet
The installation site of the ultraviolet lamp plate of LED is one or several combinations at the top, bottom, side, centre of blood vessel, the LED
Ultraviolet lamp plate go into battle column be placed with transmitting different wave length the ultraviolet lamp group of LED, the circuit configuration of the ultraviolet lamp group of the LED is in institute
The two sides and the back side of the ultraviolet lamp plate of LED are stated, the circuit is connect with the UV intensity regulation button on the control panel, described
Button controls the number of ultraviolet lamp extinguishing and/or the brightness of ultraviolet lamp by way of controlling electric current.
The outer cabinet is in cubic, protection and support internal part；The front of the outer cabinet is equipped with control panel
And sample port, the back side are equipped with exhaust outlet, thermovent and machine box door, side is equipped with fluid flow blood import and fluid flow blood exports, bottom
Portion is equipped with idler wheel or shockproof feet.
The outer cabinet material is metal.
The outer cabinet length is 1000-1500mm, in a preferred embodiment of the invention, the outer cabinet length
For 1268mm.
The outer cabinet width is 400-800mm, and in a preferred embodiment of the invention, the outer cabinet width is
635mm。
The outer cabinet height is 800-1700mm, it is preferred that the outer cabinet height is 1400-1700mm, in this hair
In a bright preferred embodiment, the outer cabinet height is 1660mm.
The control panel is equipped with temperature adjustment buttons and temperature display, UV intensity regulation button and UV intensity are aobvious
Display screen, time setting button and time display screen, sample port switch button.
The equipment can be set by heating device and refrigerating plant described in circuit connection in the temperature adjustment buttons
Temperature display is arranged on the temperature display in internal temperature, when the internal temperature is higher than setting temperature, starting heating
Device starts refrigerating plant when the internal temperature is lower than setting temperature.
The UV intensity regulation button adjusts the purple inside the equipment by the ultraviolet lamp plate of LED described in circuit connection
Outer intensity, the UV intensity are shown on the UV intensity display screen.
Time needed for inactivation treatment is arranged in the time setting button, the time showing is in the time display screen
On.
In an embodiment of the invention, the temperature display, UV intensity display screen and time display screen are equal
For number display.
The sample port switch button is stretched disk by sample described in circuit connection, control each sample stretch disk stretch out or
Retract the sample port.
The sample port is rectangle, and the rectangular length is 200-400mm, width 50-100mm, in this hair
In a bright preferred embodiment, the rectangular length is 300mm, width 70mm.
Each described sample discharge surface is equipped with one piece of movable plate, and the movable plate lower end is being hinged on the outer cabinet just
Face, upper end can free-open-close, the size of the movable plate is identical as sample port, allow the sample stretch disk stretch out or retract
The sample port facilitates taking for sample blood bag.
The material of the movable plate is alloy or plastics.
The sample port is arranged in array in outer cabinet front, the quantity of the sample port and the flexible disk quantity of the sample
Unanimously, the line number of the sample port array arrangement and columns are 2-4.In one embodiment of the invention, the sample port
Line number be 4, columns 2.
The machine box door is located at the back side of outer cabinet, and position is corresponding with the specimen holder and the ultraviolet lamp plate of LED, opens cabinet
The internal part of the equipment can be arranged, be overhauled to door.
The ventilating system includes exhaust outlet and thermovent.
The exhaust outlet is located at the side of the machine box door, and the exhaust outlet is rectangular single layer blinds diffusing air port, keeps
The equipment inner air flowing, avoids the formation of confined space.
The thermovent is located at outer cabinet lower backside, and corresponding with motor position, and the energized equipments such as motor is avoided to overheat,
Power supply line is stretched out from the thermovent, for connecting power supply.
It is divided into upper and lower two parts inside the equipment, there is partition separation in centre, and the top is equipped with specimen holder and LED is purple
The heating device, refrigerating plant and motor is arranged in outer lamp plate, the lower part.
The specimen holder is in cubic, is made of braced frame and support plate, the material of the specimen holder be metal or
Duroplasts.
The length of the specimen holder is 600-1000mm, width 200-500mm, is highly 800-1300mm, in this hair
In a bright preferred embodiment, the height of the specimen holder is 1260mm.
The specimen holder have layering point column design, the number of plies, columns and layer height determine according to actual needs, of the invention
In one preferred embodiment, the number of plies of the specimen holder is 4 layers, and columns is 2 column, a height of 300mm of layer.
Card slot is set in the support plate on the specimen holder, and the support plate between twice card slot is hollow out, for placing
The sample stretches disk, and for the card slot using the ramp design for being parallel to support plate direction, the sample disk that stretches is fixed on two
Between road card slot, and it can be moved along the slideway.
The sample disk that stretches is in cubic, and the length of the cube is 100-400mm, width 100-300mm,
In a preferred embodiment of the invention, the length of the cube is 255mm, width 205mm.
The bottom surface portions hollow out of the flexible disk of the sample, hollow-out part allows ultraviolet light to pass through, and is radiated on sample, not
Hollow-out part plays the role of supporting sample.The shape of hollow-out part is rectangular, round, triangle etc., it is preferred that the hollow out
Partial shape is rectangular.
The two sides of the flexible disk of the sample are equipped with blood vessel card slot, and for fixing packed blood vessel, the sample is stretched
Contracting try to get to the heart of a matter face non-hollow-out part be equipped with cassette tape, for fixing tubulose blood vessel, the fixed part of the cassette tape can be used
Primary and secondary patch, snap fastener etc..
The flexible disk of the sample is corresponding with corresponding sample port position, can stretch out or retract convenient for the flexible disk of the sample
The sample port.
The top or bottom of the specimen holder or blood vessel is arranged in the ultraviolet lamp plate of LED, at of the invention one
In preferred embodiment, the bottom of the specimen holder is arranged in the ultraviolet lamp plate of LED.
The lamp plate is equipped with LED ultraviolet lamp, and the LED ultraviolet lamp can choose different wave length type, and the LED is ultraviolet
Lamp is arranged in array, and the line number and columns of the array arrangement are 4-10, it is preferred that the line number and columns of the array arrangement be
6-8.In a preferred embodiment of the present invention, the LED ultraviolet lamp display arrangement is that 8 rows 8 arrange, and the ultraviolet lamp of singular row is
365nmUVA, the ultraviolet lamp of even numbers row are 310nmUVB.
Different labels are carved on lamp plate beside each LED ultraviolet lamp, to distinguish.
Circuit needed for the LED ultraviolet lamp is uniformly arranged in the two sides and the back side of the lamp plate, does not shut out the light；The electricity
Road is connect with the UV intensity regulation button on the control panel, and the button is ultraviolet to control by way of controlling electric current
The brightness of number and ultraviolet lamp that lamp extinguishes, and then adjust whole ultraviolet ray intensity.
The blood vessel is bag-shaped or tubulose.The packed blood vessel includes lighting process bag, the lighting process
The top and bottom of bag are respectively equipped with blood and enter pipe and blood effuser, and the blood, which enters on pipe and blood effuser, all to be pressed from both sides
There is flow-stopping clip, the surrounding edge of the lighting process bag is equipped with interconnecting piece hard plate.The pipe dress blood vessel includes at illumination
Reason supervisor, the both ends of lighting process supervisor are respectively set blood and enter pipe and blood effuser, the blood enter pipe and
Flow-stopping clip is all accompanied on blood effuser.The blood of each blood vessel enters pipe can be by connection hose and other blood
The blood effuser connection of liquid container.
It stretches on disk in use, the blood vessel is placed on the sample, ultraviolet light can be stretched disk by sample
Bottom surface hollow-out part, and it is radiated at blood vessel surface.When the blood vessel is fixed, the packed blood vessel surrounding
Interconnecting piece hard plate is inserted into the blood vessel card slot of the flexible disk two sides of the sample, and sample is protruded into one end of the tubulose blood vessel
The cassette tape of the flexible disk of product, and fixed with the fixed part of cassette tape.
Blood is static or flowable state in inactivation treatment, when being flowable state when blood is in inactivation treatment, by the blood
The blood of liquid container enters pipe and the blood effuser connection hose connection of another blood vessel, and the connection hose is final
Fluid flow blood import and fluid flow blood outlet from the outer cabinet side are stretched out, and connect blood source and power transmission dress
It sets, the power conveying device can be peristaltic pump.
Due to the adoption of the above technical scheme, the invention has the following advantages:
1, scheme provided by the invention can be realized the adjusting of ultraviolet ray intensity, when emitting the ultraviolet light of extra strength,
The blood inactivation treatment time can greatly shorten, and improve efficiency, and realize scale processing.
2, scheme provided by the invention is by increasing or decreasing the quantity of the LED ultraviolet lamp, arranged on a large scale or
Small-scale arrangement, realizes the scale or miniaturization of the equipment, meets the different market demands.
3, equipment provided by the invention uses full-automatic control system, by the parameter setting of the control panel, that is, controllable
It makes temperature, ultraviolet ray intensity and the processing time of the equipment, it is easy to operate.
Detailed description of the invention
Fig. 1 a is outer cabinet front schematic view of the invention.
Fig. 1 b is outer cabinet schematic rear view of the invention.
Fig. 2 is control panel schematic diagram of the invention.
Fig. 3 is specimen holder and electrical equipment schematic diagram of the invention.
Fig. 4 is the flexible disk schematic diagram of sample of the invention.
Fig. 5 is the ultraviolet lamp plate schematic diagram of LED of the invention.
Fig. 6 is blood vessel schematic diagram.
In attached drawing, the outer cabinet of 1-, 101- fluid flow blood import, the outlet of 102- fluid flow blood, 2- control panel, 201- temperature
Display screen, 202- UV intensity display screen, 203- time display screen, 204- temperature adjustment buttons, the adjusting of 205- UV intensity are pressed
Button, 207- sample port switch button, 3- sample port, 301- movable plate, 4- Shockproof base, 5- air draft is arranged in button, 206- time
Mouthful, 6- machine box door, 7- thermovent, 8- specimen holder, 801- sample stretches disk, 802- card slot, 803- slideway, 804- hollow-out part,
805- cassette tape, 806- blood vessel card slot, 9- motor, 10- heating device, 11- refrigerating plant, 12- partition, 13-LED ultraviolet lamp
Plate, 131-LED ultraviolet lamp, 132- label, 133- circuit, the packed blood vessel of 14-, 141- lighting process bag, 142- blood into
Enter pipe, 143- blood effuser, 144- flow-stopping clip, 145- interconnecting piece hard plate, 15- pipe dress blood vessel, 151- lighting process
Supervisor, 16- power supply line.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention is purged, is complete
Site preparation description.
The static blood inactivation treatment of embodiment 1
It is described to set the present invention provides a kind of application of LED ultraviolet lamp source in photochemical method blood inactivation treatment equipment
Standby 1 structure of outer cabinet is as shown in Figure 1.The Facad structure of outer cabinet 1 is as shown in Figure 1a, and outer cabinet 1 is cuboid, outer cabinet
Length is 1268mm, width 635mm, is highly 1660mm.The front setting control panel 2 and sample port 3 of outer cabinet 1.Sample
Product mouth 3 is rectangle, and the length of sample port 3 is 300mm, and width 70mm, sample port 3 is in the front of outer cabinet 1 in array row
Cloth, lines up 2 column, and each column 4.3 surface of sample port is equipped with movable plate 301, and the size of movable plate 301 is identical as sample port 3, activity
The lower end of plate 301 is hinged on 1 front of outer cabinet, upper end can free-open-close, the material of movable plate 301 is plastics, passes through sample port 3
Taking for sample is realized with movable plate 301.Outer 1 bottom of cabinet is equipped with shockproof feet 4.
The backside structure of outer cabinet 1 is as shown in Figure 1 b, and machine box door 6 is arranged in the top at outer 1 back side of cabinet, opens machine box door 6
It can arrange, the internal part of repair apparatus.Exhaust outlet 5 is set on one side door plate of machine box door 6, and exhaust outlet 5 is rectangular single layer
Blinds diffusing air port keeps the flowing of equipment inner air, avoids the formation of confined space.Heat dissipation is arranged in the lower part at outer 1 back side of cabinet
Mouth 7 avoids the energized equipments such as motor from overheating, and power supply line 16 is stretched out from thermovent 7, for connecting power supply.
The structure of control panel 2 is as shown in Fig. 2, be arranged temperature display 201, UV intensity display screen on control panel 2
202, time display screen 203, respectively temperature, UV intensity and the inactivation treatment time of display device, display screen is number
Word is shown.Display screen be correspondingly arranged separately below temperature adjustment buttons 204, UV intensity regulation button 205, the time setting by
Button 206.Temperature adjustment buttons 204 control the temperature inside equipment by circuit connection heating device 10 and refrigerating plant 11.It is purple
Outer intensity adjustment button 205 controls the UV intensity inside equipment by the ultraviolet lamp plate 13 of circuit connection LED.Sample port switch
Button 207 controls the flexible disk 801 of each sample and stretches out or retract phase by the flexible disk 801 of sample on circuit connection specimen holder 8
The sample port 3 answered.
Specimen holder 8 and installation structures inside equipment are intermediate as shown in figure 3, be divided into upper and lower two parts inside equipment
There is the separation of partition 12, top is equipped with specimen holder 8 and the ultraviolet lamp plate 13 of LED, the position of specimen holder 8 correspond to machine box door 6, and LED is ultraviolet
Motor 9, heating device 10, refrigerating plant 11 is arranged in 8 bottom of specimen holder, lower part in the setting of lamp plate 13, their position is corresponding to be dissipated
Hot mouth 7.Specimen holder 8 is in cubic, is made of braced frame and support plate, material is metal.The height of specimen holder 8 is
1260mm, specimen holder 8 have layering point column design, and the number of plies is 4 layers, and columns is 2 column, a height of 300mm of layer.Every layer of specimen holder 8 is set
The flexible disk 801 of 2 samples is set, for placing sample.
As shown in figure 4, sample stretches, disk 801 is in cubic to the structure of the flexible disk 801 of sample, and the length of cube is
255mm, width 205mm.Card slot 802 is set in the support plate of specimen holder 8, the support plate between twice card slot is hollow out,
It stretches disk 801 for placing sample, card slot 802 is designed using the slideway 803 for being parallel to support plate direction, and sample stretches disk 801
It is fixed between twice card slot 802, and can be moved along slideway 803.The bottom surface portions hollow out of the flexible disk 801 of sample, hollow-out part
804 permission ultraviolet lights pass through, and are radiated on sample, the shape of hollow-out part 804 be it is rectangular, non-hollow-out part plays support sample
The effect of product, and cassette tape 805 is arranged in non-hollow-out part, for fixing tubulose blood vessel 15.Sample stretches 801 two sides of disk
Equipped with blood vessel card slot 806, for fixing packed blood vessel.Sample stretches disk 801 and corresponding 3 position pair of sample port
It answers, can stretch out or retract the sample port 3 convenient for the flexible disk 801 of the sample, facilitate taking for sample blood bag.
The structure of the ultraviolet lamp plate 13 of LED is as shown in figure 5, the ultraviolet lamp plate 13 of LED is arranged in 8 bottom of specimen holder, LED ultraviolet lamp
Plate 13 is equipped with LED ultraviolet lamp 131, and LED ultraviolet lamp 131 is arranged in array to be arranged for 10 rows 10, and the ultraviolet lamp of singular row is
365nmUVA, the ultraviolet lamp of even numbers row are 310nmUVB.Different labels are carved on the lamp plate on each 131 side of LED ultraviolet lamp
132, to distinguish.Circuit 133 needed for LED ultraviolet lamp 131 is uniformly arranged in the two sides and the back side of the ultraviolet lamp plate 13 of LED, does not hide
It is in the light；Circuit 133 is connect with the UV intensity regulation button 205 on control panel 2, and UV intensity regulation button 205 passes through
The mode of electric current is controlled to control the number and brightness of the extinguishing of LED ultraviolet lamp 131, and then adjusts whole ultraviolet ray intensity.
Blood vessel structure as shown in fig. 6, packed blood vessel 14 include lighting process bag 141, lighting process bag 141
Top and bottom are respectively equipped with blood and enter pipe 142 and blood effuser 143, and blood enters on pipe 142 and blood effuser 143
Flow-stopping clip 144 is all accompanied, the surrounding edge of lighting process bag 141 is equipped with interconnecting piece hard plate 145.Pipe fills blood vessel 15
Lighting process supervisor 151, the both ends of lighting process supervisor 151 are respectively set blood and enter pipe 142 and blood effuser 143, blood
Liquid, which enters on pipe 142 and blood effuser 143, all accompanies flow-stopping clip 144.
When static blood inactivation treatment uses packed blood vessel 14, flow-stopping clip 144 is clamped, prevents blood from flowing out, is connect
Logical power supply line 16 presses the sample port switch button 207 of control panel 2, and the movable plate 301 of corresponding sample port 3 is opened, sample
Flexible disk 801 stretches out, and interconnecting piece hard plate 145 is inserted into the blood vessel card slot 806 of flexible 801 two sides of disk of sample, fixed
Packed blood vessel 14 presses sample port switch button 207 again, and the flexible disk 801 of corresponding sample is withdrawn, and movable plate 301 closes
It closes, button 206 is arranged in the temperature adjustment buttons 204, UV intensity regulation button 205, time for adjusting control panel 2, sets respectively
The temperature, UV intensity and time of inactivation treatment are set, ultraviolet inactivation processing is started.After treatment makes sample according to the method described above
The flexible disk 801 of product stretches out, and removes packed blood vessel 14, according to the method described above withdraws the flexible disk 801 of sample, closes power supply.
When static blood inactivation treatment is using pipe dress blood vessel 15, flow-stopping clip 144 is clamped, prevents blood from flowing out, is pressed
The flexible disk 801 of sample is stretched out according to the above method, 151- lighting process is responsible in the cassette tape 805 of the flexible disk 801 of insertion sample,
And fixing card band 805, pipe dress blood vessel 15 is fixed on sample and is stretched on disk 801.Subsequent inactivation treatment operates and uses bag
It fills identical when blood vessel 14.
2 flowable state blood inactivation treatment of embodiment
When flowable state blood inactivation treatment uses packed blood vessel 14, the machine box door 6 of outer cabinet 1 is opened, by each bag
The interconnecting piece hard plate 145 for filling blood vessel 14 is inserted into the blood vessel card slot 806 of flexible 801 two sides of disk of sample, fixing bag
Fill blood vessel 14；The blood of each packed blood vessel 14 is entered into pipe 142 and a upper packed blood vessel using hose
14 143 connection of blood effuser, the blood of first packed blood vessel 14 enter the hose of the connection of pipe 142 from outer cabinet 1
The fluid flow blood import 101 of side is stretched out, and power conveying device and blood source, the blood of the last one packed blood vessel 14 are connected
The hose that liquid stream outlet pipe 143 connects is stretched out from the fluid flow blood of outer 1 side of cabinet outlet 102, connects blood source or other containers.
Start inactivation treatment according to the equipment application method in embodiment 1, while the conveying device that turns on the power, keeps blood logical
It crosses hose and successively flows into each packed blood vessel 14, carry out the inactivation of flowable state blood.
When flowable state blood inactivation treatment is using pipe dress blood vessel 15, the machine box door 6 of outer cabinet 1 is opened, by each pipe
It fills blood vessel 15 to be inserted into the cassette tape 805 of the flexible disk 801 of sample, fixing pipe fills blood vessel 15；Using hose by each pipe
The blood of dress blood vessel 15 enters 143 connection of blood effuser of pipe 142 and upper pipe dress blood vessel 15, first pipe
The hose that the blood of dress blood vessel 15 enters the connection of pipe 142 is stretched out from the fluid flow blood import 101 of outer 1 side of cabinet, connection
Power conveying device and blood source, the hose that the blood effuser 143 that the last one pipe fills blood vessel 15 connects is from outer cabinet 1
The fluid flow blood outlet 102 of side is stretched out, and blood source or other containers are connected.
Start inactivation treatment according to the equipment application method in embodiment 1, while the conveying device that turns on the power, keeps blood logical
It crosses hose and successively flows into each pipe dress blood vessel 15, carry out the inactivation of flowable state blood.
Claims (11)
1. a kind of application of LED ultraviolet lamp source in photochemical method blood inactivation treatment equipment, which is characterized in that the LED is purple
Outer lamp source array arrangement has the ultraviolet lamp group of LED of transmitting different wave length, and ultraviolet lamp extinguishing is controlled by way of controlling electric current
Number and/or ultraviolet lamp brightness.
2. application according to claim 1, which is characterized in that the line number and columns of the LED ultraviolet lamp array arrangement be
4-10。
3. application according to claim 1, which is characterized in that the line number and columns of the LED ultraviolet lamp array arrangement be
6-8。
4. application according to claim 1, which is characterized in that the LED ultraviolet lamp source is gone out in the photochemical method blood
Installation site in processing equipment living is one or several combinations at the top, bottom, side, centre of blood vessel.
5. application according to claim 1, which is characterized in that the inactivation side that the photochemical method blood inactivation equipment uses
Method is selected from methylenum careuleum/visible-light treatment method, psoralen/UVA facture and riboflavin/UV facture.
6. a kind of fully automatic blood inactivation treatment equipment with LED ultraviolet source, which is characterized in that including outer cabinet, sample
The ultraviolet lamp plate of frame, blood vessel, LED, the outer cabinet front are equipped with control panel and sample port, and the control panel is equipped with purple
Outer intensity adjustment button, the outer cabinet interior setting specimen holder and the ultraviolet lamp plate of LED, the installation of the ultraviolet lamp plate of LED
Position is one or several combinations at the top, bottom, side, centre of blood vessel, and the ultraviolet lamp plate of LED, which is gone into battle, arranges arrangement
There is the ultraviolet lamp group of LED of transmitting different wave length, the circuit configuration of the ultraviolet lamp group of the LED is the two of the ultraviolet lamp plate of the LED
Side and the back side, the circuit are connect with the UV intensity regulation button on the control panel, and the button passes through control electric current
Mode come control ultraviolet lamp extinguishing number and/or ultraviolet lamp brightness.
7. a kind of fully automatic blood inactivation treatment equipment with LED ultraviolet source according to claim 6, feature exist
In the line number and columns of the LED ultraviolet lamp array arrangement are 4-10.
8. a kind of fully automatic blood inactivation treatment equipment with LED ultraviolet source according to claim 6, feature exist
In the line number and columns of the LED ultraviolet lamp array arrangement are 6-8.
9. a kind of fully automatic blood inactivation treatment equipment with LED ultraviolet source according to claim 6, feature exist
Temperature adjustment buttons and temperature display, time setting button and time display screen, ultraviolet strong are additionally provided in, the control panel
Spend display screen and sample port switch button；The temperature adjustment buttons are described by circuit connection heating device and refrigerating plant
Sample port switch button passes through the flexible disk of circuit control sample.
10. a kind of fully automatic blood inactivation treatment equipment with LED ultraviolet source according to claim 6, feature
It is, the specimen holder is in cubic, and has layering point column design, and the specimen holder is by braced frame and support board group
At, card slot is set in the support plate, placed between twice card slot the sample stretch disk.
11. a kind of fully automatic blood inactivation treatment equipment with LED ultraviolet source according to claim 6, feature
It is, the blood vessel is bag-shaped or tubulose, and blood is static or flowable state in processing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910152244.4A CN109908376B (en) | 2019-02-28 | 2019-02-28 | Application of LED ultraviolet lamp source in photochemical method blood inactivation treatment equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910152244.4A CN109908376B (en) | 2019-02-28 | 2019-02-28 | Application of LED ultraviolet lamp source in photochemical method blood inactivation treatment equipment |
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| Publication Number | Publication Date |
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| CN109908376A true CN109908376A (en) | 2019-06-21 |
| CN109908376B CN109908376B (en) | 2021-08-24 |
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|---|---|---|---|
| CN201910152244.4A Active CN109908376B (en) | 2019-02-28 | 2019-02-28 | Application of LED ultraviolet lamp source in photochemical method blood inactivation treatment equipment |
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Cited By (4)
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| CN110833628A (en) * | 2019-11-25 | 2020-02-25 | 四川南格尔生物科技有限公司 | Online ultraviolet inactivation process |
| CN110833626A (en) * | 2019-11-25 | 2020-02-25 | 四川南格尔生物科技有限公司 | Ultraviolet inactivation pipeline system |
| CN111494660A (en) * | 2020-04-20 | 2020-08-07 | 复旦大学 | Ultraviolet broad-spectrum sterilization device based on intelligent sensing |
| CN111840596A (en) * | 2020-06-11 | 2020-10-30 | 南岳生物制药有限公司 | Riboflavin photochemical plasma inactivation device and control system and control method thereof |
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| CN111840596A (en) * | 2020-06-11 | 2020-10-30 | 南岳生物制药有限公司 | Riboflavin photochemical plasma inactivation device and control system and control method thereof |
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