CN109894172A - A kind of micron particles self assembly device and method - Google Patents
A kind of micron particles self assembly device and method Download PDFInfo
- Publication number
- CN109894172A CN109894172A CN201910351886.7A CN201910351886A CN109894172A CN 109894172 A CN109894172 A CN 109894172A CN 201910351886 A CN201910351886 A CN 201910351886A CN 109894172 A CN109894172 A CN 109894172A
- Authority
- CN
- China
- Prior art keywords
- self assembly
- assembly device
- micron particles
- open port
- micron
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002245 particle Substances 0.000 title claims abstract description 66
- 238000001338 self-assembly Methods 0.000 title claims abstract description 39
- 238000000034 method Methods 0.000 title abstract description 15
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 7
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims description 7
- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 claims description 7
- 238000004987 plasma desorption mass spectroscopy Methods 0.000 claims description 7
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 7
- 239000000463 material Substances 0.000 claims description 4
- 230000005684 electric field Effects 0.000 abstract description 7
- 239000007787 solid Substances 0.000 description 5
- 238000006073 displacement reaction Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000012512 characterization method Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 241001415145 Acnistus arborescens Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000004377 microelectronic Methods 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 238000012536 packaging technology Methods 0.000 description 1
- 238000001259 photo etching Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
Landscapes
- Electrostatic Separation (AREA)
Abstract
The invention belongs to micron level chip field, specifically discloses a kind of micron particles self assembly device and method, assemble method have been related to dielectrophoretic force.The micron particles self assembly device is rectangular configuration, and structure includes open port, working power, earthing power supply.Micron particles self-assembling method used in the present invention is: allowing two particles to enter rectangle self assembly device by open port, the effect for powering on rear two particle by dielectrophoretic force close to each other reaches self assembly purpose.Present invention has an advantage that particle quick nondestructive self assembly under micro-meter scale;Device only passes through application electric field and is just able to achieve, and apparatus structure is simple, at low cost.
Description
Technical field
The invention belongs to micron level chip field, a kind of micron particles self assembly device and method are specifically disclosed,
Its assemble method has been related to dielectrophoretic force and has carried out particle driving.The present invention can be used for the particles self assemble technique of micron level.
Background technique
Micro-fluidic chip is a kind of emerging science for being controlled the particle in fluid for main feature with micron level
Technology, the technology have it is easy to operate, it is lossless to particle, high-precision particle manipulation is carried out in the case where low cost, be suitble to
The places such as factory, scientific research institutions, universities and colleges use.Nowadays the development of microelectronics system is increasingly accelerated, to micron level
Matching requirements are higher and higher, society be badly in need of one kind be able to achieve high-volume, fireballing flow line production micron level particle from
Packaging technology.
Summary of the invention
It is an object of that present invention to provide a kind of micron particles self assembly device and methods, and two in rectangular devices are micro-
Rice grain suspends in the solution by close as far as possible under external force flexible, squeezes during two particles are close to each other
Press liquid, liquid react on micron particles, keep micron particles close.The present apparatus can allow micron particles mutually to rely on
Self assembly is realized together.
The technical scheme is that a kind of micron particles self assembly device and method, including open port 1, opening
Port 2, working power 3, earthing power supply 4.It is connected to working power 3 on open port 1,2V voltage is provided;On open port 2
Earthing power supply 4 is connect, 0V voltage is provided.Rectangular configuration side length is 200 μm, and width is 200 μm, a height of 200 μm of solid rectangle structure.
Solution density is the incompressible Newtonian fluid of 1000kg/m3 in solid rectangle structure;Relative dielectric constant is 80 F/m;Power
Viscosity is 0.001Pas.When work, enter solid rectangle structure, work from open port 1 and open port 2 to self assembly particle
Make power supply and 2V voltage is provided;Effect of the micron particles by DC electric field in solid rectangle structure also generates between particle
Interaction, generates inhomogeneous field in the surrounding space of micron particles.In spatial non-uniform electric field and each micron particles
Reciprocation occurs for the electric dipole of generation, and this reciprocation is caused by the difference and liquid mediums of micron particles electrical property
Dielectrophoretic force is applied to caused by each micro particles, and reciprocation acts on particle by constraint.Keep micron particles mutual
It is close and finally mobile towards positive polarity direction, realize micron particles self-assembly process.
Income of the invention is: relative to other micron particles self assembly devices, the present invention realizes oneself of micron particles
Assemble method is dielectrophoretic force technology, and micron particles can be allowed close to each other and flowed to a direction.Due to the electricity of application
Force down, micron particles damaged smaller, be suitable for biological cell, micron particles and it is various to external force sensitive particles from group
Dress.Present invention work overall process only applies electric field, does not furthermore need other forms energy input.
Detailed description of the invention
Fig. 1 is the micron particles self assembly device overall structure signal X-Y scheme.
Fig. 2 is the micron particles self assembly device course of work particle displacement and flow field figure.
Fig. 3 is the micron particles self assembly device particle speed curve graph.
Specific embodiment
With reference to the accompanying drawing, it elaborates to the present invention, but a specific embodiment of the invention is without being limited thereto.
Micron particles self assembly device in a kind of DC electric field is material using PDMS, passes through the manufacture such as photoetching and development
Technique manufactures SUB mold, and will be coated on mold after cured dose of PDMS material mixing, takes off after heating cooling and shaping
Mould to obtain PDMS cavity block, then will by the coating of curing agent mixed PDMS material and PC on piece, then by being heating and curing after
It demoulds and PDMS plate is made, PDMS cavity block and plate cooperate resulting micro-structure to be the micron particles self assembly device.
Specifically, as shown in Figure 1, a kind of micron particles self assembly device in DC electric field.Including open port 1, open
Port 2, working power 3, earthing power supply 4.Self assembly region be rectangular configuration, a length of 200 μm, width be 200 μm, a height of 200 μm
Solid rectangle structure.It is connected to working power 3 at the open port 1 of rectangular configuration, is made at self assembly rectangular configuration left margin
Generate the end voltage of 2V;It is connected to earthing power supply 4 at rectangular configuration open port 2, makes to produce at self assembly rectangular configuration right margin
The end voltage of raw 0V allows in self assembly rectangular configuration and generates DC electric field.
Specifically, as shown in Fig. 2, micron particles self assembly device course of work particle displacement and flow field figure.Scheme hollow
Heart circle characterization micron particles;Arrow characterizes flow field solution flow direction;The speed of the depth characterization Solution flow rates of black and white, stream
Solution flowing is faster in, and color is deeper, otherwise the more shallow flowing of color is slower.Micron particles are under the action of dielectrophoretic force
Between draw close, realize the purpose of self assembly.
Specifically, as shown in figure 3, micron particles self assembly device particle speed curve graph.The position of ordinate expression particle
Move speed, unit be μm/s;Abscissa indicates that the distance of displacement, unit are μm.It is mobile using two grain center points as coordinate origin
Direction is positive to the right, and moving direction is negative to the left.Left figure indicates the change curve of speed, self assembly device when the movement of left side particle
Left side particle is drawn close by backward two granular center of dielectrophoretic force when work, when being displaced to two particles distance as -15 μm by
The influence that hydraulic power becomes larger makes speed lowering slowly, is finally intended to zero;Right figure indicates that the speed when movement of right particle becomes
Change curve, the right particle is leaned on by acquisition preliminary examination speed after dielectrophoretic force and to two granular centers when self assembly device works
Hold together, the influence to be become larger when being displaced to two particles distance as 15 μm by hydraulic power is intended to speed lowering slowly finally
Zero, while particle contacts with each other and realizes self assembly purpose.
It is above-mentioned can not to the present invention be limited comprehensively, other any changes made without departing from technical solution of the present invention or
Equivalent replacement mode, all within protection scope of the present invention.
Claims (6)
1. a kind of micron particles self assembly device specifically includes open port 1, open port 2, working power 3, ground voltage 4.
2. micron particles self assembly device according to claim 1, it is characterised in that: micron particles self assembly device geometry
Structure is rectangular configuration;Its geometry is processed by PDMS material.
3. micron particles self assembly device according to claim 2, it is characterised in that: micron particles self assembly device or so
Both sides are open port 1 and open port 2 respectively.
4. open port 1 according to claim 3 and open port 2, it is characterised in that: open port 1 and open port 2
For two opposite side of left and right of rectangle;Working power 3 is connect in open port 1, and the operating voltage of self assembly device is provided;In open end
Ground voltage 4 is connect in mouth 2, self assembly device is made to form closed circuit.
5. particles self assemble device according to claim 1, it is characterised in that: the particle diameter of self assembly reaches micron order
Not.
6. particles self assemble device according to claim 1, it is characterised in that: carry out micron size by dielectrophoretic force
Grain self assembly.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910351886.7A CN109894172A (en) | 2019-04-28 | 2019-04-28 | A kind of micron particles self assembly device and method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910351886.7A CN109894172A (en) | 2019-04-28 | 2019-04-28 | A kind of micron particles self assembly device and method |
Publications (1)
Publication Number | Publication Date |
---|---|
CN109894172A true CN109894172A (en) | 2019-06-18 |
Family
ID=66956553
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201910351886.7A Pending CN109894172A (en) | 2019-04-28 | 2019-04-28 | A kind of micron particles self assembly device and method |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109894172A (en) |
Citations (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101234292A (en) * | 2007-11-09 | 2008-08-06 | 东南大学 | Direction controllable microfluid dielectrophoresis granule separating device |
JP2008196943A (en) * | 2007-02-13 | 2008-08-28 | Matsushita Electric Ind Co Ltd | Measuring chip, measuring system and measuring method of biological specific reactant |
US20080289965A1 (en) * | 2005-12-21 | 2008-11-27 | The Trustees Of The University Of Pennsylvania | System and Method for Controlling Nanoparticles Using Dielectrophoretic Forces |
US20110079513A1 (en) * | 2008-04-03 | 2011-04-07 | Martin Stelzle | Microfluidic system and method for assembling and for subsequently cultivating, and subsequent analysis of complex cell arrangements |
TW201139684A (en) * | 2010-05-14 | 2011-11-16 | Univ Nat Cheng Kung | Methods enable for bio-identification and manipulation of nano-scale biomolecular |
CN103512923A (en) * | 2013-09-24 | 2014-01-15 | 西安交通大学 | Hydrogen sensor manufacturing method based on nanoparticle self-assembly mesh line structure |
US20140131204A1 (en) * | 2012-11-13 | 2014-05-15 | Academia Sinica | Molecular entrapment and enrichment |
CN104096608A (en) * | 2014-07-21 | 2014-10-15 | 东南大学 | Separated type automatic micron-size particle assembling and sorting device and manufacturing method thereof |
CN104974997A (en) * | 2015-05-28 | 2015-10-14 | 东北大学 | New cell separation method using parallel electric field type photoelectric chip |
CN106378213A (en) * | 2016-05-05 | 2017-02-08 | 海南大学 | Dielectrophoresis-based chip for separation of deformable microparticles |
CN208234919U (en) * | 2018-01-05 | 2018-12-14 | 海南大学 | A kind of U-shaped electrode red blood cell and the micro- separator of blood platelet |
CN109225366A (en) * | 2018-10-12 | 2019-01-18 | 大连海事大学 | A kind of high-pass cell separation device and method based on nano-micrometre combination channel AC dielectrophoresis |
CN109433284A (en) * | 2018-12-23 | 2019-03-08 | 海南大学 | A kind of nano particle collator based on dielectrophoretic force driving |
CN211099107U (en) * | 2019-04-28 | 2020-07-28 | 海南大学 | Micron particle self-assembly device |
-
2019
- 2019-04-28 CN CN201910351886.7A patent/CN109894172A/en active Pending
Patent Citations (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080289965A1 (en) * | 2005-12-21 | 2008-11-27 | The Trustees Of The University Of Pennsylvania | System and Method for Controlling Nanoparticles Using Dielectrophoretic Forces |
JP2008196943A (en) * | 2007-02-13 | 2008-08-28 | Matsushita Electric Ind Co Ltd | Measuring chip, measuring system and measuring method of biological specific reactant |
CN101234292A (en) * | 2007-11-09 | 2008-08-06 | 东南大学 | Direction controllable microfluid dielectrophoresis granule separating device |
US20110079513A1 (en) * | 2008-04-03 | 2011-04-07 | Martin Stelzle | Microfluidic system and method for assembling and for subsequently cultivating, and subsequent analysis of complex cell arrangements |
TW201139684A (en) * | 2010-05-14 | 2011-11-16 | Univ Nat Cheng Kung | Methods enable for bio-identification and manipulation of nano-scale biomolecular |
US20140131204A1 (en) * | 2012-11-13 | 2014-05-15 | Academia Sinica | Molecular entrapment and enrichment |
CN103512923A (en) * | 2013-09-24 | 2014-01-15 | 西安交通大学 | Hydrogen sensor manufacturing method based on nanoparticle self-assembly mesh line structure |
CN104096608A (en) * | 2014-07-21 | 2014-10-15 | 东南大学 | Separated type automatic micron-size particle assembling and sorting device and manufacturing method thereof |
CN104974997A (en) * | 2015-05-28 | 2015-10-14 | 东北大学 | New cell separation method using parallel electric field type photoelectric chip |
CN106378213A (en) * | 2016-05-05 | 2017-02-08 | 海南大学 | Dielectrophoresis-based chip for separation of deformable microparticles |
CN208234919U (en) * | 2018-01-05 | 2018-12-14 | 海南大学 | A kind of U-shaped electrode red blood cell and the micro- separator of blood platelet |
CN109225366A (en) * | 2018-10-12 | 2019-01-18 | 大连海事大学 | A kind of high-pass cell separation device and method based on nano-micrometre combination channel AC dielectrophoresis |
CN109433284A (en) * | 2018-12-23 | 2019-03-08 | 海南大学 | A kind of nano particle collator based on dielectrophoretic force driving |
CN211099107U (en) * | 2019-04-28 | 2020-07-28 | 海南大学 | Micron particle self-assembly device |
Non-Patent Citations (4)
Title |
---|
倪中华, 朱树存: "基于介电泳的生物粒子分离芯片", 东南大学学报(自然科学版), no. 05, pages 724 - 728 * |
倪中华, 顾兴中, 王跃轩: "微观作用力驱动的纳米颗粒自装配技术", 微纳电子技术, no. 10, pages 18 - 22 * |
张璐;吴晶;陈慧英;: "微米及纳米级微粒的分离与操控研究进展", 内蒙古民族大学学报(自然科学版), no. 03, pages 262 - 265 * |
曾一笑;樊磊;吴菲;谭秋林;孙东;: "基于介电电泳的粒子分离微流控芯片的研究", 仪表技术与传感器, no. 02, pages 5 - 8 * |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Kwon et al. | Electrically-driven hydrogel actuators in microfluidic channels: fabrication, characterization, and biological application | |
Tanzi et al. | Fabrication of combined-scale nano-and microfluidic polymer systems using a multilevel dry etching, electroplating and molding process | |
CN104140927A (en) | Cell position and attitude adjusting chip, device and method | |
CN103317393A (en) | Thin-layer fluid type low-stress polishing device | |
CN105058786A (en) | Coaxial focusing electro stream printing method | |
CN104998702A (en) | Preparation method of PDMS microfluidic chip based on liquid composite molding method | |
CN107574163B (en) | Method for screening magnetic nanoparticle modified cells based on light-induced dielectrophoresis device | |
CN105420763B (en) | Micro-nano electrochemical deposition processing method based on drop taylor cone | |
CN104096608A (en) | Separated type automatic micron-size particle assembling and sorting device and manufacturing method thereof | |
Rao et al. | A microfluidic electrostatic separator based on pre-charged droplets | |
CN211358388U (en) | Light-induced dielectrophoresis particle separation device based on continuous flow | |
CN103865795B (en) | Microfluidic chip for controlling cell sorting via voltage | |
CN104974997B (en) | A kind of cell novel method for separating using parallel electric field formula photoelectric chip | |
JP2020055740A (en) | Plate-shaped-material exfoliating apparatus comprising optimized discharge portion | |
CN109894172A (en) | A kind of micron particles self assembly device and method | |
CN103337300B (en) | Transparent film mosaic circuit production method by using external electric field to drive filling | |
CN104923322A (en) | Dielectrophoresis particle separation micro-fluidic chip | |
CN204039383U (en) | A kind of cell pose regulates chip and device | |
CN105842484A (en) | SICM amplitude modulation imaging mode scanning device and method | |
CN211099107U (en) | Micron particle self-assembly device | |
CN104923324A (en) | Preparation method for PDMS microfluidic chip based on photosensitive resin curing molding | |
Yao et al. | A novel integrated microfluidic chip for on-demand electrostatic droplet charging and sorting | |
CN210935012U (en) | Micron granule clamping device | |
KR20080008826A (en) | A method for moving of a conductive droplet by charging thereof through direct contact with electrodes | |
CN209866339U (en) | Nanoparticle classification device based on dielectrophoresis force driving |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |