CN109893188A - A kind of degradable type tendon stapler - Google Patents
A kind of degradable type tendon stapler Download PDFInfo
- Publication number
- CN109893188A CN109893188A CN201910317101.4A CN201910317101A CN109893188A CN 109893188 A CN109893188 A CN 109893188A CN 201910317101 A CN201910317101 A CN 201910317101A CN 109893188 A CN109893188 A CN 109893188A
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- degradable
- locking piece
- tendon
- zinc
- locating rod
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- 229910052725 zinc Inorganic materials 0.000 claims description 9
- 239000011701 zinc Substances 0.000 claims description 9
- 229910052751 metal Inorganic materials 0.000 claims description 8
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- 229910000881 Cu alloy Inorganic materials 0.000 claims description 5
- 229910000882 Ca alloy Inorganic materials 0.000 claims description 3
- VVZJQVZLLAFNFB-UHFFFAOYSA-N [Sr].[Zn].[Li] Chemical compound [Sr].[Zn].[Li] VVZJQVZLLAFNFB-UHFFFAOYSA-N 0.000 claims description 3
- ISZIYIIDGMIKEV-UHFFFAOYSA-N [Zn].[Li].[Ca] Chemical compound [Zn].[Li].[Ca] ISZIYIIDGMIKEV-UHFFFAOYSA-N 0.000 claims description 3
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- 229910001316 Ag alloy Inorganic materials 0.000 claims description 2
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- BSWGGJHLVUUXTL-UHFFFAOYSA-N silver zinc Chemical compound [Zn].[Ag] BSWGGJHLVUUXTL-UHFFFAOYSA-N 0.000 claims description 2
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- 238000010586 diagram Methods 0.000 description 4
- 239000011777 magnesium Substances 0.000 description 4
- 238000005259 measurement Methods 0.000 description 4
- 238000009958 sewing Methods 0.000 description 4
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 3
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 3
- 239000011575 calcium Substances 0.000 description 3
- 239000010949 copper Substances 0.000 description 3
- TVZPLCNGKSPOJA-UHFFFAOYSA-N copper zinc Chemical compound [Cu].[Zn] TVZPLCNGKSPOJA-UHFFFAOYSA-N 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
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- 238000005516 engineering process Methods 0.000 description 3
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- 239000000463 material Substances 0.000 description 3
- 230000010287 polarization Effects 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 229910052712 strontium Inorganic materials 0.000 description 3
- 229910052692 Dysprosium Inorganic materials 0.000 description 2
- 229910052688 Gadolinium Inorganic materials 0.000 description 2
- 239000012981 Hank's balanced salt solution Substances 0.000 description 2
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 2
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- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 2
- 229910052727 yttrium Inorganic materials 0.000 description 2
- VWQVUPCCIRVNHF-UHFFFAOYSA-N yttrium atom Chemical compound [Y] VWQVUPCCIRVNHF-UHFFFAOYSA-N 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 1
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- 229910001278 Sr alloy Inorganic materials 0.000 description 1
- 229910001069 Ti alloy Inorganic materials 0.000 description 1
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 description 1
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- 229910007565 Zn—Cu Inorganic materials 0.000 description 1
- WCULPSIYAQDUJW-UHFFFAOYSA-N [Li].[Sr] Chemical compound [Li].[Sr] WCULPSIYAQDUJW-UHFFFAOYSA-N 0.000 description 1
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- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
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Abstract
The invention discloses a kind of degradable type tendon staplers.Including locating rod and locking piece, wherein the quantity at least two of locating rod, the both ends of the locating rod all have lock hole, pass through for the locking piece, have locking mechanism on the locking piece, for locking the relative position between locating rod and locking piece；The locking mechanism is protrusion, the quantity of the protrusion be it is multiple, the lock hole can be passed through in one direction, and blocked in the opposite direction by the edge of the lock hole.The type tendon stapler is made of degradable metal material, can finally be fully absorbed by human body.The problems such as type tendon stapler of the invention can be such that the tendon broken ends of fractured bone is kept in contact without carrying out suture, reduce the secondary damage to the broken ends of fractured bone, can also be effectively relieved post-operation adhesion, tendon function reduction.
Description
Technical field
The present invention relates to a kind of degradable type tendon stapler more particularly to a kind of degradable type tendon staplers of zinc-base.
Background technique
Tendon injury is most commonly seen damage, at this stage clinically for the treatment method of patient's first choice of tendon injury
That suture is repaired, clinically common tendon suture method has much at present, wherein it is more commonly used including Kessler method,
Kleinert method, saliva laxative remedy and traditional " 8 " word sewing, other methods are mostly the improvement and improvement on the basis of the method.
However since traditional suturing method receiving tension is larger, easily there is the case where suture breaks or broken ends of fractured bone dislocation；And tendon suture
It often will appear adhesion of tendon afterwards, and then postoperative function caused to restore poor, influence tendon function.
Clinically it is disconnected to be all that needlework directly draw tendon over to one's side by the interspersed suture of different modes for various tendon repair technologies
End, suture direction are based on longitudinal direction (tendon long axis direction), and different sewing methods is exactly to add on the basis of longitudinal direction
Oblique, transverse direction, the skill of handling needles of lasso.And all restorative procedures are all sewn within 5~8mm of the tendon broken ends of fractured bone.This needle
There are two deadly defects for line recovery technique: 1, tendon is to constitute collagenous fibres by Tenocyte cell and collagen, and the latter is accumulated into
Beam, group, further constitute tendon.Collagenous fibres and its beam, group in tendon are all in longitudinal arrangement, there is a fixed gap therebetween,
The strength thus longitudinally pulled, which is easy to draw, slits；2,5~8mm of tendon broken ends of fractured bone meeting swelling, hyperemia, softening in healing process of tendon,
Suture easily cuts the tissue of this softening open, and causes previous anastomotic to be split, draws and slit.Therefore, tendon shift is clinically required
It brakes 3 weeks afterwards.
In order to improve this case, the Chinese patent document of Publication No. CN101991445A provides a kind of center type flesh
Tendon matching device, it is made of body portion, two sutures and two sewing needles, and body portion is long made of degradable biological material
Strip structure, middle section are the cylindroid bodily form, and both ends are the elliptic cone bodily form, one end of two sutures both ends with body portion respectively
It is connected, the other end of two sutures is connected with the tail portion of two sewing needles respectively.The central type tendon stapler is by tendon two
The broken ends of fractured bone is sewn on a type tendon stapler, while suture tension direction row can be made to draw over to one's side, allow suture after tendon by
Force is located at tendon broken ends of fractured bone 8mm with remote.But the stapler still needs to suture when in use, still can cause to the tendon broken ends of fractured bone
Secondary damage, and the power granted of body portion is in fact or longitudinal force, is still easy to draw to slit.
In order to reinforce the intensity of absorbable suture, the Chinese patent document of Publication No. CN206285291U provides one
Kind magnesium-base metal tendon anastomosis device, and two kinds of structures of U-shaped and V-arrangement are devised, the apparatus structure is simple, operates also not multiple
Miscellaneous, but it coincide, principle, which is still, makes tendon longitudinal stress, still not can avoid and is easy to draw open-minded problem.And it is above two
Stapler can not be finely adjusted once selected the pricked position of syringe needle, it is more difficult to guarantee best match result.In addition, degradable magnesium
The ultimate tensile strength multidigit of Base Metal is in this section 200-300MPa, and corresponding, clinically used titanium alloy is planted now
Enter object, ultimate tensile strength is between 500MPa-1000MPa, and elongation percentage is 20% or so, it is seen that magnesium-base metal is still unable to satisfy
The requirement of orthopedic implant.
Zn-ef ficiency is the essential trace elements of the human body, and it is albumen that the Zn-ef ficiency of human body 90%, which is stored in muscle and bone,
One of most important element, the growth of participant's somatocyte development, gene expression, immune system in matter synthesis and energy metabolism
With a large amount of physiological reaction processes such as nervous system.In the research process to degradable zinc-base metal, it has been found that zinc-base metal
There are good biocompatibility and safety, and excellent in mechanical performance, ultimate tensile strength reaches as high as 680MPa, extends
Rate 10%-80%, to sum up theoretically zinc-base metal can achieve the basic demand for preparing orthopedic implant.In addition to this, zinc
Also there is facilitation for the growth of tendon.Therefore, these prompt us that zinc-base metal is used in the design of type tendon stapler.
Summary of the invention
In view of the above-mentioned problems in the prior art, the object of the present invention is to provide one kind without suturing tendon, can
The damage to the tendon broken ends of fractured bone is reduced, and can effectively mitigate suture posterior synechia, the degradable type tendon stapler of good mechanical performance.
To achieve the above object, the present invention provides a kind of degradable type tendon stapler, including locating rod and locking piece,
The quantity at least two of middle locating rod, the both ends of the locating rod all have lock hole, pass through for the locking piece, described
There is locking mechanism, for locking the relative position between locating rod and locking piece on locking piece.The type tendon stapler is by can
Degradation metal material is made, and can finally be fully absorbed by human body.
The locating rod can be horizontally through tendon, and two locating rods can be such as each passed through to the both sides at rupture of tendon
Tendon, and the relative position of both sides tendon is locked by the lock hole at locating rod both ends by locking piece, the flesh for being broken both sides
Tendon contacts with each other, and there is no need to suture to coincide at rupture of tendon.
Therefore, in order to preferably pass through tendon, the locating rod preferably has acuminous cylindrical bar, and the shape is not only
One, than cylinders, elliptical cylinder-shape, the square column type with fillet are all feasible.
The quantity of the locating rod can select 2-6 a as needed, and preferably 4, because of the fixed force phase of 4 locating rods
To larger, and convenient for adjusting to degrees of tensions, and 4 quantity is unlikely to the biggish damage of tendon generation.
Further, the locking mechanism is protrusion, the quantity of the protrusion be it is multiple, can pass through in one direction described in
Lock hole, and blocked in the opposite direction by the edge of the lock hole.Locking principle above-mentioned is similar in life and commonly uses
Band principle.
Preferably, the locking piece is the degradable silk thread with protrusion, particularly preferably degradable metal wire.
In the preferred embodiment of the present invention, the locking piece has axially symmetric convex two-by-two on main shaft
It rises, all protrusions all have outwardly extending angle wheel profile, and all angle wheel profiles are in the master along the locking piece
At least piecewise or all extend towards identical direction on axis, and the distalmost end of the angle wheel profile is to locking piece master
The distance of axis is slightly larger than the edge of the lock hole to the distance of locking piece main shaft." being slightly larger than " described herein is that must expire
The foot locking piece can be locked the condition that bore edges block by lock hole in one direction in the other directions.
The shape of the protrusion can be triangle, trapezoidal etc., but from the ease of production for, be directly made into straight
The protrusion of linear reversed acanthoid is most preferred.
Further, the locking piece can be one be also possible to it is two or more.In a kind of preferred implementation of the invention
In mode, the locking piece is the degradable metal wire for having pairs of linear hangnail, and from the both ends of locking piece main shaft
Two sections of linear hangnails being open in opposite directions (having opposite inclined direction) is set respectively inwards, it can be two after U-shaped bending
End is each passed through the lock hole of two sides, finally tenses at the both ends of wire together, knots or does not knot and all may be used.Of the invention
In another preferred embodiment, the locking piece is separated two degradable metal wires for having pairs of linear hangnail,
And the end of wire all has stuck design, can not pass through lock hole, after their front end is each passed through the lock hole of two sides,
It tenses respectively again, knots or do not knot and all may be used.
The present invention can change the size of type tendon stapler according to the tendon injury of different parts, length including locating rod,
The quantity of diameter and the disconnected place's both sides locating rod of tendon.
Further, the length of the locating rod is preferably 2-4cm, and diameter is preferably 2-3mm, and the diameter of the lock hole is excellent
It is selected as 1.5-2mm, the diameter of the locking piece main shaft is preferably 1-1.5mm.
Locating rod needs in the present invention, which play the role of fixedlying positioning, not to be moved, is indeformable, therefore it is preferably by strong
Higher degradable metal material is spent to be made.
Preferably, the degradable type tendon stapler is made of Zr-based materials；The Zr-based materials are for pure zinc or containing zinc
Mass fraction reaches 90% or more kirsite.
Further, single or Determination of multiple metal elements can be added in above-mentioned kirsite, addible element includes but is not limited to:
Magnesium Mg, copper Cu, silver Ag, lithium Li, manganese Mn, strontium Sr, calcium Ca, yttrium Y, gadolinium G, dysprosium Dy；Wherein the quality of every kind of element in the alloy accounts for
Than being no more than 5%, and the total mass fraction of each element is no more than 10%；Further, wherein silver, lithium, manganese, strontium, yttrium, gadolinium, dysprosium
The respective mass fraction of element is no more than 1%, more preferably less than 0.6%.
In the preferred embodiment of the present invention, the kirsite is binary zinc-containing alloy, such as zinc magnesium alloy, zinc-copper
Alloy, manganese alloy, zinc-silver alloy etc.；In another preferred embodiment of the invention, the kirsite is ternary zinc
Alloy, such as zinc-magnesium calcium alloy, zinc lithium-copper alloy, zinc lithium calcium alloy, zinc lithium strontium alloy, zinc-magnesium copper alloy.
In better embodiment of the invention, the kirsite is bianry alloy, for example, zinc-copper bianry alloy, wherein
The mass fraction of cupric is 1%-3%, further preferably 1.5%-2.5%；Alternatively, zinc-manganese bianry alloy, the wherein matter of manganese
Amount score is 0.1-0.6%, further preferably 0.3-0.5%.
In another better embodiment of the invention, the kirsite is ternary alloy three-partalloy containing lithium, such as zinc lithium calcium ternary
Alloy or zinc lithium strontium ternary alloy three-partalloy, wherein the sum of mass fraction of lithium calcium or lithium strontium is not more than 1.5%.
The present invention has following advantageous effects:
(1) type tendon stapler of the invention fixes the position at the tendon both ends of fracture, nothing using locating rod and locking piece
Need to carry out suture can be such that the tendon broken ends of fractured bone is kept in contact, and reduce the secondary damage to the broken ends of fractured bone, post-operation adhesion can also be effectively relieved,
The problems such as tendon function reduction；
(2) present invention has used for reference band principle to position and lock the tendon both ends of fracture, the stapler structure letter of design
It is single, it is easy production；
(3) locating rod of the invention is laterally to fix tendon, that is, gives the support force of tendon transverse direction, can avoid longitudinal draw
Power, which draws tendon, slits；
(4) compared with degradable magnesium Base Metal, degradable zinc-base metal can provide higher tensile strength, meet in orthopaedics
The basic demand of plant can maintain mechanical stability in early stage；
(5) gradually degrade in degradable zinc-containing alloy release zinc ion, magnesium ion, copper ion etc. can provide antibacterial, promote
The biological functions such as skeletonization further enhance the superiority of zinc-base metal orthopaedics application.
It is described further below with reference to technical effect of the attached drawing to design of the invention, specific structure and generation, with
It is fully understood from the purpose of the present invention, feature and effect.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of a preferred embodiment of type tendon stapler of the present invention；
Fig. 2 is the structural schematic diagram of the another preferred embodiment of type tendon stapler of the present invention；
Fig. 3 is the overall structure diagram of locking piece in Fig. 1 embodiment；
Fig. 4 is the schematic diagram of locking piece protrusion different structure in type tendon stapler of the present invention, and a is linear, and b is triangle
Shape, c are trapezoidal；
In attached drawing, 1, locating rod；2, lock hole；3, locking piece；4, locking mechanism；5, tendon；6, stuck key.
Specific embodiment
Embodiment 1
A kind of preferred construction of degradable type tendon stapler of the invention is as shown in Figure 1, the type tendon stapler includes four
Locating rod 1 and a locking piece 3, the both ends of locating rod 1 all have lock hole 2, and locking piece 3 is the degradable metal of a root long
Silk, has the locking mechanism 4 that arranges in pairs thereon, and locking mechanism 4 is the linear projection (hangnail) for being inclined outwardly extension, and institute
The distance for stating distalmost end to the wire of extension relief straight lines is slightly larger than the edge of lock hole 2 to the distance of wire, therefore locks
Determine hole 2 to pass through for locking piece 3, and only just may pass through lock hole 2 along the inclined direction of linear projection, opposite direction is
It can not pass through, can be locked instead.The principle is similar to common band principle in life.By Fig. 1 and Fig. 3 it is found that this reality
It applies the linear projection in example and is divided into two sections, respectively along the position of wire to intermediate portion since the both ends of wire
Place is set, beveled is all inside.
As shown in Figure 1, the locating rod 1 is horizontally through tendon at work, therefore, the main structure of locating rod 1
For cylinder, one end has tip, can facilitate piercing tendon.Than cylinders, elliptical cylinder-shape, the square column with fillet
The design of shape is also all feasible.Locating rod quantity in the present embodiment is 4, but 2-6 locating rod in a practical situation
Quantity is all common, and breaking part both sides can be selected to use the positioning of different number according to the situation of rupture of tendon
Bar positions.
Locator 1 first can be inserted through the disconnected place both sides of tendon during installation and need to position by the type tendon stapler in Fig. 1
Position, expose the lock hole 2 at both ends, then one end of locking mechanism 4 passed through to again the tendon on the side of locator 1, paid attention to not
Direction hangnail is pulled in tendon, in order to avoid causing biggish damage to tendon, then the both ends of locking mechanism 4 are each passed through this
The lock hole 2 of all locators in side tenses the both ends of locking mechanism 4 as needed, makes to break finally along the direction of arrow in figure
The tendon both ends split contact with each other, and can knot or not knot after determining position, as long as locking.The advantages of present embodiment, exists
As long as in drawing an one metal wire that can tense tendon, and two sides are easy symmetrically.
Certain damage can be generated to tendon in view of locking piece 4 penetrates in tendon, therefore, provide this hair in Fig. 2 again
Bright another preferred embodiment uses two separated locking pieces 3 in the embodiment, they can be each passed through tendon two sides
Lock hole 2, and the end of locking piece 3 has stuck key 6, can be stuck on lock hole 2, for the end of fixedly locked part 3,
But the shortcomings that embodiment, is, the degree that two sides tense is more difficult to control just the same, is easy to produce anisopleual.
Triangle and trapezoidal convex shape are also shown other than above-mentioned linear projection, in Fig. 4, except this with
Outside, other any shapes for meeting the principle of the invention are all feasible.
The present invention can change the size of type tendon stapler according to the tendon injury of different parts, length including locating rod,
Diameter etc..The length of locating rod 1 is preferably 2-4cm, and diameter is preferably 2-3mm, and the diameter of lock hole 2 is preferably 1.5-2mm, lock
The diameter for determining 3 main shaft of part is preferably 1-1.5mm.
Embodiment 2 is used for the degradable stapler of rupture of Achilles tendon healing
Zn-Mn system bianry alloy is selected, (Mn wt0.4%, ultimate tensile strength UTS=260MPa, is bent with Zn-0.4Mn
Take intensity YS=160MPa, elongation percentage > 40%) locating rod of diameter 2mm, length 3cm is prepared, and in away from locating rod both ends 3mm
Locate the circular hole of one diameter 1.5mm of each preparation and prepares overall length hangnail wire, diameter as lock hole, and with Zn-0.4Mn alloy
For 1.25mm.
Appear in use, cutting, position the heel string broken ends of fractured bone, is then respectively successively placed in 3 locating rods to both sides along the broken ends of fractured bone, keeps
Spacing 5mm or so, then by hangnail wire, direction shown in arrow sequentially passes through the reserved circular hole in 1 both ends of locating rod along Fig. 1,
After passing through whole locating rods, gradually Strain lock determines wire, until the tendon broken ends of fractured bone on both sides contacts with each other.
Embodiment 3 is used for the degradable stapler of rupture of patellar tendon healing
Zn-Cu system bianry alloy is selected, with Zn-2Cu (Cu wt2%, UTS=270MPa, YS=230MPa, elongation percentage >
40%) locating rod of diameter 3mm, length 3cm are prepared, and each circular hole for preparing a diameter 2mm at away from locating rod both ends 3mm
Overall length hangnail wire, diameter 1.5mm are prepared as lock hole, and with Zn-2Cu alloy.
In use, knee joint median incision, appears the positioning kneecap tendon broken ends of fractured bone, 4 are respectively successively then placed in both sides along the broken ends of fractured bone
Locating rod keeps spacing 5mm or so, and then by hangnail wire, direction shown in arrow sequentially passes through 1 both ends of locating rod along Fig. 1
Reserved circular hole, after passing through whole locating rods, gradually Strain lock determines wire, until the tendon broken ends of fractured bone on both sides contacts with each other.
Embodiment 4 is used for the degradable stapler of rupture of Achilles tendon healing
Zn-Li-Sr system ternary alloy three-partalloy is selected, with Zn-0.4Li-0.1Sr (Li wt0.4%, Sr wt0.1%, UTS=
505MPa, YS=372MPa, elongation percentage > 50%) locating rod of diameter 2mm, length 3cm is prepared, and in away from locating rod both ends
The circular hole of one diameter 1.5mm of each preparation prepares overall length hangnail gold as lock hole, and with Zn-0.4Li-0.1Sr alloy at 3mm
Belong to silk, diameter 1.25mm.
Appear in use, cutting, position the heel string broken ends of fractured bone, is then respectively successively placed in 3 locating rods to both sides along the broken ends of fractured bone, keeps
Spacing 5mm or so, then by hangnail wire, direction shown in arrow sequentially passes through the reserved circular hole in locating rod both ends along Fig. 1,
After passing through whole locating rods, gradually Strain lock determines wire, until the tendon broken ends of fractured bone on both sides contacts with each other.
Embodiment 5 is used for the degradable stapler of rupture of patellar tendon healing
Zn-Li-Ca system ternary alloy three-partalloy is selected, with Zn-0.4Li-0.1Ca (Li wt0.4%, Ca wt0.1%, UTS=
500MPa, YS=430MPa, elongation percentage > 15%) locating rod of diameter 3mm, length 3cm is prepared, and in away from locating rod both ends
The circular hole of one diameter 2mm of each preparation prepares overall length hangnail metal as lock hole, and with Zn-0.4Li-0.1Ca alloy at 3mm
Silk, diameter 1.5mm.
In use, knee joint median incision, appears the positioning kneecap tendon broken ends of fractured bone, 4 are respectively successively then placed in both sides along the broken ends of fractured bone
Locating rod keeps spacing 5mm or so, and then by hangnail wire, direction shown in arrow sequentially passes through locating rod both ends along Fig. 1
Reserved circular hole, after passing through whole locating rods, gradually Strain lock determines wire, until the tendon broken ends of fractured bone on both sides contacts with each other.
Embodiment 6
Its chemical property and corrosive nature are tested according to following normal process to zinc-containing alloy selected by the present invention:
(1) electro-chemical test
At room temperature using electrochemical workstation (Autolab, Metrohm, Switzerland), Hank ' s solution
In tested.Electro-chemical test is used for using the three-electrode system of platinum electrode-saturated calomel electrode (SCE).To each sample
Carry out open circuit potential (Open-circuit potential, OCP) monitoring in 5400 seconds.Electrochemical impedance spectroscopy
(Electrochemical impedance spectroscopy, EIS) test is in 10mV, measurement frequency 105To 10-2Hz
Under conditions of carry out.Potentiodynamic polarization test (Potentiodynamic polarization is then carried out with the rate of 1mV/s
), test test area 0.2826cm2(φ6mm).Each sample group at least carries out five measurements.By Linear fit and
Tafel extrapolation method analyzes the cathode of polarization curve and the corrosion parameter of anode portion, including open circuit potential
(OCP), corrosion potential (Ecorr) and corrosion electric current density (icorr)。
1.2 immersion test
Immersion test carries out in 37 DEG C of Hank ' s solution.Pass through pH meter (Mettler during immersion in different time points
FiveEasy pH FE20K) recording solution pH value.After removing corrosion product, in electronic balance (XS105, METTLER
TOLERDO the weight that sample is measured on) is lost, and measurement sensitivity 0.1mg, every group averagely carries out five measurements.According to following
Formula calculates external corrosion rate: C=Δ m/ ρ At, wherein C is the corrosion rate as unit of mm/, and Δ m is weight loss,
ρ is the density of material, and A is the surface area initially impregnated, and t is Implantation Time.
The results are shown in Table 1 for partial test.
The electrochemical parameter (37 ± 0.2 DEG C) of pure zinc and kirsite in 1 SBF solution of table
Note: the number in bracket is standard deviation
The preferred embodiment of the present invention has been described in detail above.It should be appreciated that those skilled in the art without
It needs creative work according to the present invention can conceive and makes many modifications and variations.Therefore, all technologies in the art
Personnel are available by logical analysis, reasoning, or a limited experiment on the basis of existing technology under this invention's idea
Technical solution, all should be within the scope of protection determined by the claims.
Claims (10)
1. a kind of degradable type tendon stapler, which is characterized in that including locating rod and locking piece, wherein the quantity of the locating rod
At least two, the both ends of the locating rod all have lock hole, pass through for the locking piece, have lock on the locking piece
Mechanism is determined, for locking the relative position between the locating rod and the locking piece.
2. degradable type tendon stapler as described in claim 1, which is characterized in that the locating rod is to have acuminous cylinder
Shape bar.
3. degradable type tendon stapler as described in claim 1, which is characterized in that the locking mechanism is protrusion, described convex
The quantity risen be it is multiple, the lock hole can be passed through in one direction, and in the opposite direction by the side of the lock hole
Edge blocks.
4. degradable type tendon stapler as claimed in claim 1 or 3, which is characterized in that the locking piece is with protrusion
Degradable silk thread.
5. degradable type tendon stapler as claimed in claim 3, which is characterized in that the locking piece has two-by-two on main shaft
Axially symmetric protrusion, all protrusions all have outwardly extending angle wheel profile, and all angle wheel profiles exist
At least piecewise or all extend towards identical direction, and the slope profile along the main shaft of the locking piece
The distance of the distalmost end of line to the main shaft is slightly larger than the edge of the lock hole to the distance of the main shaft.
6. degradable type tendon stapler as claimed in claim 3, which is characterized in that the shape of the protrusion is triangle, ladder
Shape or linear.
7. degradable type tendon stapler as claimed in claim 1 or 3, which is characterized in that the locking piece be one at
To the degradable metal wire of linear hangnail, and two sections are arranged respectively inwards from the both ends of the locking piece main shaft and is open in opposite directions
Linear hangnail.
8. degradable type tendon stapler as claimed in claim 1 or 3, which is characterized in that the degradable girdle device is by pure zinc
Or the mass fraction containing zinc reaches 90% or more kirsite and is made.
9. degradable type tendon stapler as claimed in claim 8, which is characterized in that the degradable girdle device is closed by zinc-magnesium
Gold, pltine, zinc-silver alloy or manganese alloy are made.
10. degradable type tendon stapler as claimed in claim 8, which is characterized in that the degradable girdle device is by zinc-magnesium calcium
Alloy, zinc lithium-copper alloy, zinc lithium calcium, zinc lithium strontium or zinc-magnesium copper alloy are made.
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