CN109892594A - Composition, preparation method and application with hypolipemic function - Google Patents
Composition, preparation method and application with hypolipemic function Download PDFInfo
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Abstract
The embodiment of the present application discloses a kind of composition with hypolipemic function, the raw material including following parts by weight: 120 ~ 380 parts of blueberry；40 ~ 80 parts of fish oil micro-capsule powder；20 ~ 60 parts of dextrin.The composition can be applied to the health food or drug of preparation reducing blood lipid, pass through the synergistic effect of blueberry and fish oil, the high-density lipoprotein cholesterol content in serum can be effectively improved, Triglycerides in Serum, total cholesterol, low density lipoprotein cholesterol content are reduced, to play the role of preferable reducing blood lipid.In addition, the taste of the composition is preferable, it is highly-safe.
Description
Technical field
The present invention relates to blood-fat reducing composition fields, and in particular to a kind of composition with hypolipemic function.In addition, this
Invent the preparation method for further relating to the composition and the application in health food or drug.
Background technique
One of the main reason for hyperlipidemia is a kind of disease of abnormalities of sugar/lipid metabolism, is initiation cardiovascular and cerebrovascular disease.Stream
Row disease learns investigation and shows that hyperlipidemia incidence is 30% or more in general population, and the incidence of the elderly is up to 60% or more.
Drug currently used for hyperlipidemia treatment is mostly chemical synthesis, not only expensive, but also side effect is more.Therefore, explore and
Screening has the living resources of regulating blood lipid action significant.
Deep sea fish oil major physiological active constituent is n-3 polyunsaturated fatty acid (n-3 PUFAs), wherein 22 carbon six
The mass fraction of olefin(e) acid (DHA) and eicosapentaenoic acid (EPA) can achieve 20%~30%, have prevention cardiovascular and cerebrovascular disease
Disease, hypertension, artery sclerosis, reduces blood viscosity and adjusts the functions such as blood lipid thrombosis.Although fish oil product has good guarantor
Health-care function and favored by masses, but fish oil itself has fishlike smell, while DHA in fish oil and EPA are containing multiple double bonds, pole
It is oxidizable, it on the one hand reduces and adjusts blood lipid and other effects, on the other hand generate unacceptable peculiar smell.These defects are significantly
Limit its application in production and processing.
Summary of the invention
In order to solve the above technical problems, the application uses the fish oil micro-capsule powder and blueberry of special ratios, pass through the two
Synergistic effect, to obtain a kind of composition with preferable effect for reducing blood fat.Meanwhile the composition taste is preferable, safety
Property it is high.
In a first aspect, this application provides a kind of compositions with hypolipemic function, by the raw material of following parts by weight
Composition:
120~380 parts of blueberry；
40~80 parts of fish oil micro-capsule powder；
20~60 parts of dextrin；
Wherein, 120~380 parts of blueberries in the composition are 10~30 parts of blueberry cream, and the density of the blueberry cream is
1.28-1.33g/cm3。
Optionally, include the raw material of following parts by weight in the composition:
10~20 parts of blueberry cream；
60~80 parts of fish oil micro-capsule powder；
20~60 parts of dextrin.
Second aspect, this application provides a kind of preparation methods of composition with hypolipemic function, including following step
It is rapid:
It extracts blueberry and obtains blueberry cream；
By 40~80 parts of fish oil micro-capsule powder, 20~60 parts of dextrin and 10~30 parts of blueberry cream mixings, the first mixing is obtained
Object；
By the first mixture softwood, pelletize, it is dry, obtain the composition with hypolipemic function.
Optionally, extracting the step of blueberry obtains blueberry cream includes:
By blueberry be added 55%~65% edible alcohol in, obtain the first mixed liquor, wherein the edible alcohol with it is described
The mass ratio of blueberry is 1:6~8；
The pH value of first mixed liquor is adjusted to 3.8~4.2；
Temperature extraction takes 50~70 minutes at 50 DEG C~55 DEG C, obtains extracting solution；
The edible alcohol in the extracting solution is recycled, and is concentrated into density 1.28-1.33g/cm3, obtain blueberry cream.
Optionally, the pH value of first mixed liquor is adjusted using glacial acetic acid.
Optionally, the step of temperature extraction takes 1 hour, obtains extracting solution at 50 DEG C, comprising:
It repeats the step of temperature extraction takes 1 hour at 50 DEG C at least twice, filtered fluid is obtained by filtration, merges the filtering
Liquid obtains extracting solution.
Optionally, by 40~80 parts of fish oil micro-capsule powder, 20~60 parts of dextrin and 10~30 parts of blueberry cream mixings, the is obtained
The step of one mixture, comprising:
By 40~80 parts and 20~60 parts of the dextrin mixings of fish oil micro-capsule powder, the second mixture is obtained；
By second mixture and 10~30 parts of blueberry cream mixings, the first mixture is obtained.
The third aspect, the application provide first aspect any composition preparation for reducing blood lipid health food or
Application in drug.
In combinations of the above object, blueberry is monarch drug in a prescription in side, and pectin abundant plays reduction cholesterol, anti-stop in blueberry
Pulse atherosclerosis promotes the effect of cardiovascular health.Fish oil micro-capsule powder is ministerial drug in side, and playing reduces blood viscosity and adjusting blood
The effects of rouge.Dextrin is auxiliary material.The collaboration of both blueberry and fish oil micro-capsule powder, can strengthen blood vessel, improve blood circulation, prevent
The generation of blood clot, plays effect for reducing blood fat jointly.
The composition is formulated by pure natural medical, prescription is simple, is used to prepare the health food of auxiliary reducing blood lipid
Or drug, definite effect.The composition has no toxic side effect, safety with higher.In addition, the composition does not have DHA and EPA
Peculiar smell caused by aoxidizing, taste is preferable, and eater's acceptance is preferable.
Specific embodiment
The application will be described in detail by specific embodiment and embodiment below.
This application provides a kind of composition with hypolipemic function, the raw material including following parts by weight: blueberry 120
~380 parts, 40~80 parts of fish oil micro-capsule powder and 20~60 parts of dextrin.
Wherein, blueberry also known as blue berry, be cowberry platymiscium, be known as " fruit queen ", " fruit of U.S. pupil "." herbal guiding principle
Mesh " in record, it is sour-sweet edible after Blueberry is mature, can be used as medicine, there is the benefits of strengthening tendons QI invigorating, supplementing the kidney to control the nocturnal.Blueberry has
Neural aging is prevented, cardiac function, improving eyesight, the unique medical care effect such as anticancer and anti-cardiovascular disease are enhanced.Modern medicine
Pharmacological research shows that blueberry can strengthen capillary, improves blood circulation, weakens the viscosity of blood platelet, prevent blood clot
Generation, long-term use can enhance cardio cerebral function.
EPA and DHA is rich in fish oil.Wherein, the unobstructed blood vessel of EPA energy, helps to maintain unobstructed blood vessel, and pre- preventing thrombosis produces
It is raw, the generation of apoplexy or myocardial infarction is prevented, the fat accumulated in blood, prevention of arterial hardening and prevention tip can also be removed
The generation of angiemphraxis.EPA is able to suppress low density lipoprotein cholesterol, reduces its adventitious deposit on wall in the blood vessels, and
And high-density lipoprotein cholesterol can be assisted to remove fat extra on vascular wall.The brain cell that DHA is is formed, develops and is transported
Make indispensable material base, can promote, coordinate the conduction of neural circuit, maintains the normal operation of brain cell,
The elderly supplements in right amount, facilitates active thinking, has the function of preventing senile dementia.
Fish oil micro-capsule powder is the manufactured powder after being embedded fish oil specific technique with wall material using fish oil as core material
Shape fish oil product.Fish oil micro-capsule powder both maintained the prevention cardiovascular and cerebrovascular disease of fish oil, thrombosis, hypertension, artery sclerosis,
It reduces blood viscosity and adjusts the characteristic of blood lipid, and compensate for the deficiency of liquid fish oil, avoid the DHA and EPA oxidation in fish oil, keep away
Exempt from function reduction and generates peculiar smell.
In the composition of the application, blueberry is monarch drug in a prescription in side, and pectin abundant plays reduction cholesterol in blueberry, is prevented
Atherosclerosis promotes the effect of cardiovascular health.Fish oil micro-capsule powder is ministerial drug in side, and playing reduces blood viscosity and adjusting
The effects of blood lipid.Dextrin is auxiliary material.The collaboration of both blueberry and fish oil micro-capsule powder, can strengthen blood vessel, improve blood circulation, prevent
The generation of hemostasis grumeleuse.
The composition is formulated by pure natural medical, prescription is simple, is used to prepare the health food of auxiliary reducing blood lipid
Or drug, definite effect.When being applied to health food or drug, other can also be added again only with the composition
Necessary auxiliary material, the application are not construed as limiting this.The composition has no toxic side effect, safety with higher.In addition, the combination
Object does not have DHA and EPA to aoxidize generated peculiar smell, and taste is preferable, and eater's acceptance is preferable.
Optionally, 120~380 parts of blueberries in combinations of the above object can use blueberry cream, and dosage is that density is
1.28-1.33g/cm310~30 parts of blueberry cream.Blueberry cream can extract to obtain using blueberry.
In one implementation, blueberry can be added in 55%~65% edible alcohol first, obtains the first mixing
Liquid, wherein the mass ratio of edible alcohol and blueberry is 1:6~8.Then, the pH value of the first mixed liquor is adjusted to suitable value,
Such as adjust to 3.8~4.2, glacial acetic acid can be used by adjusting pH value.Temperature extraction takes 50~70 minutes at 50 DEG C~55 DEG C again,
Obtain extracting solution.
Optionally, the concentration of edible alcohol can be 60%.When blueberry is mixed with edible alcohol, edible alcohol and indigo plant
The mass ratio of the certain kind of berries is 1:6.The pH value of first mixed liquor is adjusted to 4.0.Temperature extraction, which takes, only to extract once, can also extract two
It is secondary or more than twice.When extracting multiple, the liquid repeatedly extracted can be filtered respectively, be then combined with all filtrates, obtain
To extracting solution.The edible alcohol in extracting solution is finally recycled, and is concentrated into density 1.28-1.33g/cm3, obtain blueberry cream.Into
Optionally, the temperature that temperature extraction takes is 50 DEG C to one step, and the time is 1 hour.
It preferably, include the raw material of following parts by weight in the composition: 10~20 parts of blueberry cream；Fish oil micro-capsule powder 60
~80 parts；20~60 parts of dextrin.It is also shown from subsequent test result, the composition of the application is under above-mentioned specific proportion
Lipid-lowering effect is more preferably.
The application also provides the preparation method of the composition above-mentioned with hypolipemic function, comprising the following steps:
(a) it extracts blueberry and obtains blueberry cream；
(b) by 40~80 parts of fish oil micro-capsule powder, 20~60 parts of dextrin and 10~30 parts of blueberry cream mixings, it is mixed to obtain first
Close object；
(c) it by the first mixture softwood, pelletizes, it is dry, obtain the composition with hypolipemic function.
Blueberry cream is extracted in step (a) can be prepared using method above-mentioned, and details are not described herein again.In step (b)
In a kind of implementation, first fish oil micro-capsule powder and dextrin can be mixed, obtain the second mixture；Then by the second mixture
It is mixed with blueberry cream, obtains the first mixture.Softwood processed, granulation, the dry step that can be in wet granulation in step (c),
It can also include the steps that whole grain after drying.The preparation method simple process, is convenient for industrialized production.
The technical solution of the application will be further illustrated by specific embodiment below.
It should be noted that the blueberry in following embodiment is provided by Tonghua He Yun modern agriculture limited liability company, fish
Oil microcapsule powder is purchased from German BASF and limits company.Total cholesterol (TC) assay kit, triglyceride (TG) measure reagent
Box, high-density lipoprotein cholesterol (HDL-C) assay kit, low density lipoprotein cholesterol (LDL-C) assay kit, purchase
From Beijing Zhongsheng Beikong Biological Science & Technology Co., Ltd..Analysis other chemical reagent used are that domestic analysis is pure.
SD rat used by pharmacodynamic test be cleaning grade, half male and half female, age of mouse 2~3 months, 180~200g of weight,
(Ji) -2018-0013 is provided by Jilin University's Animal Experimental Study center.
Electric-heated thermostatic water bath, Guo Hua Instrument Ltd.；Eddy mixer, Industrial Co., Ltd., upper Nereid section；UV
1600 type ultraviolet-uisible spectrophotometers, Beijing Rayleigh Analytical Instrument Co., Ltd；6050 type vacuum oven of DZF, the upper macro instrument of Nereid
Device equipment Co., Ltd；Electronic balance, Beijing Sai Duolisi instrument system Co., Ltd.Other not specified reagents and instrument
Device can be directly commercially available.
Embodiment 1
Fish oil micro-capsule powder 40g and dextrin 60g are taken, is mixed；Blueberry cream 30g separately is taken, is mixed with said mixture, is made soft
Material is pelletized, dry, and whole grain obtains composition 1.
Embodiment 2
Fish oil micro-capsule powder 70g and dextrin 20g are taken, is mixed；Blueberry cream 10g separately is taken, is mixed with said mixture, is made soft
Material is pelletized, dry, and whole grain obtains composition 2.
Embodiment 3
Fish oil micro-capsule powder 60g and dextrin 40 g are taken, is mixed；Blueberry cream 20g separately is taken, is mixed with said mixture, is made soft
Material is pelletized, dry, and whole grain obtains composition 3.
Embodiment 4
Fish oil micro-capsule powder 60g and dextrin 20g are taken, is mixed；Blueberry cream 10g separately is taken, is mixed with said mixture, is made soft
Material is pelletized, dry, and whole grain obtains composition 4.
Embodiment 5
Fish oil micro-capsule powder 80g and dextrin 40 g are taken, is mixed；Blueberry cream 20g separately is taken, is mixed with said mixture, is made soft
Material is pelletized, dry, and whole grain obtains composition 5.
Embodiment 6
Fish oil micro-capsule powder 70g and dextrin 40 g are taken, is mixed；Blueberry cream 10g separately is taken, is mixed with said mixture, is made soft
Material is pelletized, dry, and whole grain obtains composition 6.
Embodiment 7
Fish oil micro-capsule powder 60g and dextrin 50g are taken, is mixed；Blueberry cream 10g separately is taken, is mixed with said mixture, is made soft
Material is pelletized, dry, and whole grain obtains composition 7.
Embodiment 8
Fish oil micro-capsule powder 70g and dextrin 40 g are taken, is mixed；Blueberry cream 20g separately is taken, is mixed with said mixture, is made soft
Material is pelletized, dry, and whole grain obtains composition 8.
Embodiment 9
Fish oil micro-capsule powder 80g and dextrin 50g are taken, is mixed；Blueberry cream 10g separately is taken, is mixed with said mixture, is made soft
Material is pelletized, dry, and whole grain obtains composition 9.
Effect example
(1) sample preparation
(1.1) blueberry group: taking blueberry cream 10g, adds water 50ml to dissolve, as sample solution.
(1.2) fish oil micro-capsule powder group: taking fish oil micro-capsule powder 10g, adds water 50ml to dissolve, as sample solution.
(1.3) blueberry-fish oil micro-capsule powder group: composition each 10g of 1-9 sample in aforementioned 9 embodiments is taken respectively, is added
Water 50ml dissolution, as sample solution.
(2) animal packet, modeling and administration
Cleaning grade male SD rat 70, weight (180 ± 20) g is provided by Laboratory Animal Center of Jilin University.It will experiment
Rat feeds 5d with normal diet, after adapting to environment, is randomly divided into 14 groups by weight: negative control, hyperlipidemia model, blueberry group,
Fish oil micro-capsule powder group, blueberry-fish oil micro-capsule powder group, Examples 1 to 9 group, are raised respectively by experimental design with not by every group 5
Same feed, initially enters experiment periods.
By each group rat by group sub-cage rearing, in addition to control group is raised with basal feed, other groups are raised with high lipid food.Each group
Daily stomach-filling processing is as follows: blueberry group, fish oil micro-capsule powder group, blueberry-fish oil micro-capsule powder group, Examples 1 to 9 group are given respectively
Sample is given, control group and hyperlipidemia model group give the physiological saline of same volume.It freely ingests drinking-water, feeding time 40d.40d
Afterwards, fasting 12h, arteria carotis communis blood sampling, 3000r are centrifuged 15min and separate serum, survey blood lipid level.
(3) statistical analysis
Experimental data is handled with SPSS17.0 statistical software, and experimental result is indicated with x ± s, using variance analysis, P
< 0.05 with for significant difference, P < 0.01 is with extremely significant sex differernce.Statistical result is as shown in table 1-3 in (4).
(4) statistical result
(4.1) changes of weight is compared with the control group after the experiment of each dosage group rat
1 each group rat of table experiment front and back changes of weight situation (x ± s, g)
Note:▲Compared with model group, there is significant difference (P < 0.05)；▲▲Compared with model group, there is extremely significant sex differernce
(P < 0.01)；* compared with Normal group, there is significant difference (P < 0.05)；* has extremely significant compared with Normal group
Sex differernce (P < 0.01).Similarly hereinafter.
As can be seen from Table 1, model group rats weight is significantly higher than negative control group, i.e., and normal group.Administration group, i.e., it is blue
9 groups of the certain kind of berries-fish oil micro-capsule powder group, average weight significant (P < 0.05) are lower than model group.Blueberry group, fish oil micro-capsule powder
Difference reaches the level of signifiance between group, blueberry-fish oil micro-capsule powder group.Blueberry group, fish oil micro-capsule powder group, blueberry-fish oil are micro-
Capsule powder group rat body weight relative model group significant (P < 0.05) reduces, and blueberry group, fish oil micro-capsule powder group, blueberry-fish oil are micro-
Rat body weight significant difference (P < 0.05) between capsule powder group.Thus illustrate, blueberry-fish oil micro-capsule powder group has reduction rat
The effect of weight.
(4.2) influence of the different groups to hyperlipidemia rats blood lipid level
Using rat blood serum as material, triglycerides (TG), total cholesterol (TC), low density lipoprotein cholesterol are analyzed
(LDL-C), high-density lipoprotein cholesterol (HDL-C) etc. blood lipids 4.Serum TC, TG content height are referring mainly to for hyperlipemia
Mark, it is effective anti arteriosclerosis (AS) factor that HDL-C, which can transport Arterial Cholesterol and be decomposed into cholic acid to liver,.Simultaneously
It calculates atherogenic index (Ather osclerosisindex, AI), according to formula AI1=(TC-HDL-C)/HDL-C and AI2
=LDL-C/HDL-C calculates the AI of each group rat, to reflect that the size of the risk of artery sclerosis occurs for body.
Influence of the different groups of table 2 to experimental rat blood lipid level
As can be seen from Table 2, model group triglycerides (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-
C) content significant (P < 0.05) is higher than negative control group, and high-density lipoprotein cholesterol (HDL-C) content significant (P < 0.05) is low
In negative control group.9 groups of administration group, i.e. blueberry-fish oil micro-capsule powder group, TG, TC, LDL-C content are significant (P < 0.05)
Lower than model group.Difference reaches the level of signifiance between blueberry group, fish oil micro-capsule powder group, blueberry-fish oil micro-capsule powder group.Blueberry
Group, fish oil micro-capsule powder group, blueberry-fish oil micro-capsule powder group HDL-C content relative model group significant (P < 0.05) increase, blueberry
HDL-C content difference is significant (P < 0.05) between group, fish oil micro-capsule powder group, blueberry-fish oil micro-capsule powder group.
Thus illustrating, blueberry-fish oil micro-capsule powder group has the function of reducing TG, TC, LDL-C in High fat diet rats serum,
And the effect of HDL-C is improved, and there are a certain amount to imitate dependence.
(4.3) influence of the different groups to hyperlipidemia rats atherogenic index
The atherogenic index of the different group experimental rats of table 3
As shown in Table 3, rat is after induction high in fat, atherogenic index AI1(TC-HDL-C)/HDL-C and AI2(LDL-
C/HDL-C) significant to increase.Blueberry group, fish oil micro-capsule powder group, blueberry-fish oil micro-capsule powder group AI1And AI2Compared with model group
It significantly reduces (P < 0.05), AI between blueberry group, fish oil micro-capsule powder group, blueberry-fish oil micro-capsule powder group1Difference reaches significant
Horizontal (P < 0.05), blueberry-fish oil micro-capsule powder group AI have dropped down to normal level.Blueberry-fish oil micro-capsule powder group and blueberry group,
Fish oil micro-capsule powder group AI2Significant difference.
Said effect test result shows that blueberry-fish oil micro-capsule powder group can significantly improve in hyperlipidemia rats serum
HDL-C content, while reducing TC, TG, LDLC content in serum.By changing to experiment front and back rat body weight, triglycerides
(TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) content are moved
Arteries and veins hardenability value AI1(TC-HDL-C)/HDL-C and AI2(LDL-C/HDL-C) measurement of biochemical indicators, it was demonstrated that in the application such as
Composition effect for reducing blood fat it is significant.
In addition, the active state of mouse is without exception in whole experiment process, and detection process Biochemical Indexes are no different
Often.This shows that the composition of the application has no significant effect animal subject health, safety with higher.
Specific case used herein is expounded embodiments of the present invention, and the explanation of above embodiments is
It is used to help understand method and its core concept of the invention.It should be pointed out that coming for those skilled in the art
It says, without departing from the principle of the present invention, can be with several improvements and modifications are made to the present invention, these improvement and modification
It also falls within the protection scope of the claims of the present invention.
Claims (7)
1. a kind of composition with hypolipemic function, which is characterized in that be made of the raw material of following parts by weight:
120 ~ 380 parts of blueberry；
40 ~ 80 parts of fish oil micro-capsule powder；
20 ~ 60 parts of dextrin；
Wherein, 120 ~ 380 parts of blueberries in the composition are 10 ~ 30 parts of blueberry cream, and the density of the blueberry cream is 1.28-
1.33g/cm3。
2. composition according to claim 1, which is characterized in that include the original of following parts by weight in the composition
Material:
10 ~ 20 parts of blueberry cream；
60 ~ 80 parts of fish oil micro-capsule powder；
20 ~ 60 parts of dextrin.
3. a kind of preparation method of the composition with hypolipemic function, which comprises the following steps:
It extracts blueberry and obtains blueberry cream；
By 20 ~ 60 parts and 10 ~ 30 parts of blueberry cream 40 ~ 80 parts of fish oil micro-capsule powder, dextrin mixings, the first mixture is obtained；
By the first mixture softwood, pelletize, it is dry, obtain the composition with hypolipemic function；
Wherein, extracting the step of blueberry obtains blueberry cream includes:
Blueberry is added in 55% ~ 65% edible alcohol, the first mixed liquor is obtained, wherein the edible alcohol and the blueberry
Mass ratio is 1:6 ~ 8；
The pH value of first mixed liquor is adjusted to 3.8 ~ 4.2；
Temperature extraction takes 50 ~ 70 minutes at 50 DEG C ~ 55 DEG C, obtains extracting solution；
The edible alcohol in the extracting solution is recycled, and is concentrated into 1.28 ~ 1.33 g/cm of density3, obtain blueberry cream.
4. preparation method according to claim 3, which is characterized in that adjust the pH of first mixed liquor using glacial acetic acid
Value.
5. preparation method according to claim 3, which is characterized in that temperature extraction takes 1 hour at 50 DEG C, is extracted
The step of liquid, comprising:
It repeats the step of temperature extraction takes 1 hour at 50 DEG C at least twice, filtered fluid is obtained by filtration, merges the filtered fluid, obtains
To extracting solution.
6. preparation method according to claim 3, which is characterized in that by 40 ~ 80 parts of fish oil micro-capsule powder, dextrin 20 ~ 60
The step of part mixes with 10 ~ 30 parts of blueberry cream, obtains the first mixture, comprising:
By 40 ~ 80 parts and 20 ~ 60 parts of the dextrin mixings of fish oil micro-capsule powder, the second mixture is obtained；
By second mixture and 10 ~ 30 parts of blueberry cream mixings, the first mixture is obtained.
7. application of any composition of claim 1-2 in the health food or drug that preparation is used for reducing blood lipid.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106543A (en) * | 2011-01-24 | 2011-06-29 | 李占学 | Blueberry vegetable oil soft capsules and production process thereof |
| CN108402465A (en) * | 2018-03-09 | 2018-08-17 | 北京素维生物科技有限公司 | A kind of micro-capsule compound powder and its preparation process containing peculiar smell oils |
| CN108703373A (en) * | 2018-05-28 | 2018-10-26 | 广州智康元健康食品有限公司 | A kind of seven color nutrients |
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2019
- 2019-03-06 CN CN201910167100.6A patent/CN109892594A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106543A (en) * | 2011-01-24 | 2011-06-29 | 李占学 | Blueberry vegetable oil soft capsules and production process thereof |
| CN108402465A (en) * | 2018-03-09 | 2018-08-17 | 北京素维生物科技有限公司 | A kind of micro-capsule compound powder and its preparation process containing peculiar smell oils |
| CN108703373A (en) * | 2018-05-28 | 2018-10-26 | 广州智康元健康食品有限公司 | A kind of seven color nutrients |
Non-Patent Citations (2)
| Title |
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| 李颖畅等: "蓝莓花色苷的降血脂和抗氧化作用 ", 《食品与发酵工业》 * |
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