CN109872804A - A kind of automatic radiotherapy planning system and its application method - Google Patents
A kind of automatic radiotherapy planning system and its application method Download PDFInfo
- Publication number
- CN109872804A CN109872804A CN201910106475.1A CN201910106475A CN109872804A CN 109872804 A CN109872804 A CN 109872804A CN 201910106475 A CN201910106475 A CN 201910106475A CN 109872804 A CN109872804 A CN 109872804A
- Authority
- CN
- China
- Prior art keywords
- radiotherapy planning
- radiotherapy
- present image
- current
- planning
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Radiation-Therapy Devices (AREA)
Abstract
The invention discloses a kind of automatic radiotherapy planning systems, and the system comprises have the data reception module for receiving patient data, the data server for storing patient medical data, the automatic automatic radiotherapy planning module for modifying radiotherapy planning and the data transmission blocks for sending radiotherapy planning.Automatic radiotherapy planning system user provided by the invention only needs to upload with reference to CT image, with reference to delineating and refer to radiotherapy planning, automatic radiotherapy planning system can automatically generate the radiotherapy planning after secondary positioning, accuracy rate is high, the efficiency for improving the secondary formulation of radiotherapy planning greatly reduces doctor's workload.
Description
Technical field
The invention belongs to medical radioactive instrument field more particularly to a kind of automatic radiotherapy planning systems and its application method.
Background technique
One course for the treatment of of radiotherapy usually requires one month or the longer time, first according to the initial fixed of patient before radiotherapy starts
Bit image generates radiotherapy planning.But the location and shape of patient's tumour would generally change in entire Patients During Radiotherapy, this
The deviation for occurring radiological dose in Patients During Radiotherapy is resulted in, radiotherapeutic effect is not only influenced, more likely will affect the normal of patient
Organ-tissue leads to complication.
In order to solve this problem, it usually needs to carry out patient after radiotherapy starts a period of time in the prior art
Reorientation obtains the new image of patient by reorientation, and doctor re-starts according to new images delineates and formulate radiotherapy planning, but
It is that this process needs to consume the very big workload of doctor.
Summary of the invention
In order to solve the above-mentioned technical problem.The present invention proposes a kind of automatic radiotherapy planning system and its application method, utilizes
With reference to radiotherapy planning, the plan after relocating is automatically generated, the workload of doctor is greatly reduced.Specific technical solution is as follows.
A kind of automatic radiotherapy planning system, the system comprises data reception module, data server, automatic radiotherapy plannings
Module, data transmission blocks.
Preferably
The data reception module for receiving patient with reference to radiotherapy data and present image, and is saved into data
Server；Wherein,
It is described with reference to radiotherapy data include reference picture, with reference to delineate, with reference to radiotherapy planning and reference dose；It is described current
Image is the image newly obtained after patient relocates；
The data server, for storing all medical datas of patient；
The automatic radiotherapy planning module, after data reception module receives present image automatically according to patient's name and
ID goes on data server to inquire and obtain the reference radiotherapy data of the patient；And three are carried out to reference picture and present image
Image registration is tieed up, 3 D deformation vector field of the present image relative to reference picture is obtained；And according to the 3 D deformation vector
, it will be mapped on present image with reference to delineating, acquisition is currently delineated, and the equal centers in reference radiotherapy planning are mapped to
On present image, the equal centers of current radiotherapy planning are obtained；Further according to the 3 D deformation vector in the region of interest of setting
, it modifies to reference radiotherapy planning and generates current radiotherapy planning；It is calculated separately again with reference to radiotherapy planning and current radiotherapy meter
It draws in the dosage distribution currently delineated, counts the dose volume data of each organ；Finally, by present image, currently delineate,
Current radiotherapy planning is saved in data server；
The data transmission blocks, the current radiotherapy planning for confirming physics teacher are sent to scheduling software and carry out scheduling
Or it is sent to other radiotherapy servers and carries out scheduling and treatment.
Preferably, the automatic radiotherapy planning module includes display and confirmation module；
The display and confirmation module can make physics teacher check and confirm whether currently delineating for given patient be accurate,
Check and confirm whether current radiotherapy planning correct, comparison with reference to radiotherapy planning with reference to delineate, with reference to radiotherapy planning current
It delineates, current radiotherapy planning is in the dosage and dose volume histogram currently delineated.
Preferably, reference picture, with reference to the figure once positioned before delineating, being respectively referred to reference to radiotherapy planning and reference dose
As, delineate, radiotherapy planning and dosage.
Preferably, the automatic radiotherapy planning module, which modifies to reference radiotherapy planning, generates the tool of current radiotherapy planning
Body step are as follows:
(1) the 3 D deformation vector field according to present image relative to reference picture, present image is generated as and is referred to
The identical blending image of image coverage area；
(2) it is determined according to the 3 D deformation vector field in the region of interest of setting described with reference to each beam in radiotherapy planning
The two dimension deformation vector field of transmitted intensity on direction；
(3) two dimension in corresponding beam direction is penetrated according to the two dimension deformation vector field of transmitted intensity in each beam direction
Line intensity distribution is deformed, and two-dimentional ray density distribution new in each beam direction is generated；
(4) according to two-dimentional ray density distribution new in each beam direction, corresponding grating and tungsten door movement number are generated
According to get arrive new radiotherapy planning.
Preferably, the region of interest in the step (2) includes target area and jeopardizes organ.
Preferably, in the step (2) target area and jeopardize organ determine it is described with reference to each beam side in radiotherapy planning
Weight when the two dimension deformation vector field of upward transmitted intensity is different.
Application method based on above-mentioned automatic radiotherapy planning system, which comprises
(1) image for newly obtaining patient, i.e. present image upload to automatic radiotherapy planning system；
(2) the automatic radiotherapy planning module inquires on data server and obtains the trouble according to patient's name and ID
The reference radiotherapy data of person；It is described with reference to radiotherapy data include reference picture, with reference to delineate, with reference to radiotherapy planning and with reference to agent
Amount；
(3) the automatic radiotherapy planning module carries out 3-D image registration to reference picture and present image, obtains current
3 D deformation vector field of the image relative to reference picture；
(4) the automatic radiotherapy planning module will be mapped to current figure with reference to delineating according to the 3 D deformation vector field
As upper, obtain currently delineate, by reference radiotherapy planning etc. centers be mapped on present image, obtain current radiotherapy meter
The equal centers drawn；
(5) the automatic radiotherapy planning module puts reference according to the 3 D deformation vector field in the region of interest of setting
Treatment plan, which is modified, generates current radiotherapy planning；
(6) the automatic radiotherapy planning module, which is calculated separately, delineates with reference to radiotherapy planning and current radiotherapy planning currently
Dosage distribution, count the dose volume data of each organ；
(7) the automatic radiotherapy planning module is delineated by present image, currently, current radiotherapy planning is saved in data service
Device；
(8) currently delineating with whether current radiotherapy planning is accurate for the patient is checked and confirmed to physics teacher given patient,
Comparison with reference to radiotherapy planning with reference to delineate, with reference to radiotherapy planning currently delineate, current radiotherapy planning is currently being delineated
Dosage and dose volume histogram；
(9) if physics teacher confirms that current radiotherapy planning is correct, the current radiotherapy planning that will confirm that be sent to scheduling software into
Row scheduling；
(10) it if physics teacher does not receive current radiotherapy planning, is currently delineated or re-optimization radiotherapy meter according to reason modification
It draws, until obtaining acceptable current radiotherapy planning, confirms current radiotherapy planning, the current radiotherapy planning that will confirm that is sent to row
Journey software carries out scheduling.
Preferably, it modifies in the step (5) to reference radiotherapy planning and generates the specific steps of current radiotherapy planning
Are as follows:
(5.1) the 3 D deformation vector field according to present image relative to reference picture, present image is generated as and is joined
Examine the identical blending image of image coverage area；
(5.2) it is determined in the reference radiotherapy planning according to the 3 D deformation vector field in the region of interest of setting and is each penetrated
The two dimension deformation vector field of the upper transmitted intensity of Shu Fangxiang；
(5.3) according to the two dimension deformation vector field of transmitted intensity in each beam direction to the two dimension in corresponding beam direction
Ray density distribution is deformed, and two-dimentional ray density distribution new in each beam direction is generated；
(5.4) according to two-dimentional ray density distribution new in each beam direction, corresponding grating and the movement of tungsten door are generated
Data to get arrive new radiotherapy planning.
Preferably, the region of interest in the step (5.2) includes target area and jeopardizes organ.
Preferably, in the step (5.2) target area and jeopardize organ determine it is described with reference to each beam in radiotherapy planning
Weight is different when the two dimension deformation vector field of transmitted intensity on direction.
Preferably, reference picture, with reference to the figure once positioned before delineating, being respectively referred to reference to radiotherapy planning and reference dose
As, delineate, radiotherapy planning and dosage.
Preferably, the step is carried out by the display of the automatic radiotherapy planning module and confirmation module, described automatic
Radiotherapy planning module reads related data from data server.
A kind of automatic radiotherapy planning apparatus, described device include:
At least one processor；And
Memory is stored with executable instruction on the memory, and the executable instruction is by least one described processing
Device executes, and described device is caused to realize following method:
Obtain the new image of patient, i.e. present image；
According to patient's name and ID inquiry and the reference radiotherapy data for obtaining the patient；It is described to include with reference to radiotherapy data
Reference picture, with reference to delineate, with reference to radiotherapy planning and reference dose；
3-D image registration is carried out to reference picture and present image, obtains three-dimensional of the present image relative to reference picture
Deform vector field；It according to the 3 D deformation vector field, will be mapped on present image with reference to delineating, acquisition is currently delineated, incited somebody to action
It is mapped on present image with reference to the equal centers in radiotherapy planning, obtains the equal centers of current radiotherapy planning；Root again
According to the 3 D deformation vector field in the region of interest of setting, modifies to reference radiotherapy planning and generate current radiotherapy planning；Again
It calculates separately with reference to radiotherapy planning and current radiotherapy planning in the dosage distribution currently delineated, counts the dosage body of each organ
Volume data；And it saves present image, currently delineate, current radiotherapy planning.
Preferably, described pair of reference radiotherapy planning, which is modified, generates the specific steps of current radiotherapy planning are as follows:
(1) according to the 3 D deformation vector field, present image is generated as melt identical with reference picture coverage area
Close image；
(2) it is determined according to the 3 D deformation vector field in the region of interest of setting described with reference to each beam in radiotherapy planning
The two dimension deformation vector field of transmitted intensity on direction；
(3) two dimension in corresponding beam direction is penetrated according to the two dimension deformation vector field of transmitted intensity in each beam direction
Line intensity distribution is deformed, and two-dimentional ray density distribution new in each beam direction is generated；
(4) according to two-dimentional ray density distribution new in each beam direction, corresponding grating and tungsten door movement number are generated
According to get arrive new radiotherapy planning.
Preferably, the region of interest in the step (2) includes target area and jeopardizes organ.
Preferably, target area described in the step (2) and jeopardize organ determine it is described with reference to each penetrating in radiotherapy planning
Weight is different when the two dimension deformation vector field of the upper transmitted intensity of Shu Fangxiang.
A kind of computer-readable storage media, including executable instruction, when described instruction is executed by least one processor,
Realize following method:
Obtain the new image of patient, i.e. present image；
According to patient's name and ID inquiry and the reference radiotherapy data for obtaining the patient；It is described to include with reference to radiotherapy data
Reference picture, with reference to delineate, with reference to radiotherapy planning and reference dose；
3-D image registration is carried out to reference picture and present image, obtains three-dimensional of the present image relative to reference picture
Deform vector field；It according to the 3 D deformation vector field, will be mapped on present image with reference to delineating, acquisition is currently delineated, incited somebody to action
It is mapped on present image with reference to the equal centers in radiotherapy planning, obtains the equal centers of current radiotherapy planning；Root again
According to the 3 D deformation vector field in the region of interest of setting, modifies to reference radiotherapy planning and generate current radiotherapy planning；Again
It calculates separately with reference to radiotherapy planning and current radiotherapy planning in the dosage distribution currently delineated, counts the dosage body of each organ
Volume data；And it saves present image, currently delineate, current radiotherapy planning.
Preferably, described pair of reference radiotherapy planning, which is modified, generates the specific steps of current radiotherapy planning are as follows:
(1) according to the 3 D deformation vector field, present image is generated as melt identical with reference picture coverage area
Close image；
(2) it is determined according to the 3 D deformation vector field in the region of interest of setting described with reference to each beam in radiotherapy planning
The two dimension deformation vector field of transmitted intensity on direction；
(3) two dimension in corresponding beam direction is penetrated according to the two dimension deformation vector field of transmitted intensity in each beam direction
Line intensity distribution is deformed, and two-dimentional ray density distribution new in each beam direction is generated；
(4) according to two-dimentional ray density distribution new in each beam direction, corresponding grating and tungsten door movement number are generated
According to get arrive new radiotherapy planning.
Preferably, the region of interest in the step (2) includes target area and jeopardizes organ.
Preferably, target area described in the step (2) and jeopardize organ determine it is described with reference to each penetrating in radiotherapy planning
Weight is different when the two dimension deformation vector field of the upper transmitted intensity of Shu Fangxiang.
By using the combination of one or more technical solution in the above summary of the invention, the present invention at least has below
The utility model has the advantages that the present invention is based on 3-D image registration technique, user only needs to upload reference picture, with reference to delineating and refer to radiotherapy
Plan, automatic radiotherapy planning system can automatically generate the radiotherapy planning after reorientation, and accuracy rate is high, improves radiotherapy planning two
The efficiency of secondary formulation greatly reduces doctor's workload；Artificial intelligence technology is applied in radiotherapy planning formulation, doctor is assisted
Carry out it is secondary delineate with secondary formulation, realize the specified regulation and standardization of radiotherapy planning and homogenize.
It should be understood that above general description and following detailed description be only it is exemplary and explanatory, not
The application can be limited.
Detailed description of the invention
In order to illustrate more clearly of the embodiment of the present disclosure or technical solution in the prior art, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
Disclosed some embodiments for those of ordinary skill in the art without creative efforts, can be with
Other attached drawings are obtained according to these figures.
Fig. 1 is a kind of example system configuration schematic diagram of automatic radiotherapy planning system
Specific embodiment
Below in conjunction with drawings and examples, the present invention is described in further detail.Aforementioned and other mesh of the invention
, features, aspects and advantages will be apparent, to enable those skilled in the art's refer to the instruction text real accordingly
It applies.
It is understood that specific embodiment described herein is used only for explaining the present invention, rather than to of the invention
It limits.It also should be noted that only the parts related to the present invention are shown for ease of description, in attached drawing and it is not all
Structure.It should be mentioned that some exemplary embodiments are described as making before exemplary embodiment is discussed in greater detail
The processing or method described for flow chart.Although operations (or step) are described as the processing of sequence by flow chart, its
In many operations can be implemented concurrently, concomitantly or simultaneously.In addition, the sequence of operations can be pacified again
Row.The processing can be terminated when its operations are completed, it is also possible to have the additional step being not included in attached drawing.Institute
Stating processing can cope in method, function, regulation, subroutine, subprogram etc..
It is only to be not intended to be limiting the application merely for for the purpose of describing particular embodiments in term used in this application.
It is also intended in the application and the "an" of singular used in the attached claims, " described " and "the" including majority
Form, unless the context clearly indicates other meaning.It is also understood that term "and/or" used herein refers to and wraps
It may be combined containing one or more associated any or all of project listed.
Embodiment 1
A kind of automatic radiotherapy planning system 100, the system comprises data reception module 101, data server 102, from
Dynamic radiotherapy planning module 103 and data transmission blocks 104.
The data reception module 101, for receiving patient with reference to the figure newly obtained after radiotherapy data and patient's reorientation
As (that is, present image), and it is saved into data server 102；Wherein,
The data server 102, for storing all medical datas of patient；
The automatic radiotherapy planning module 103, automatically according to patient after data reception module 101 receives present image
Name and ID go on data server 102 to inquire and obtain the reference radiotherapy data of the patient；And to reference picture and currently
Image carries out 3-D image registration, obtains 3 D deformation vector field of the present image relative to reference picture；And according to described three
Dimension deformation vector field, will be mapped on present image with reference to delineating, and acquisition is currently delineated, by the equal centers in reference radiotherapy planning
Position is mapped on present image, obtains the equal centers of current radiotherapy planning；Further according to three in the region of interest of setting
Dimension deformation vector field, modifies to reference radiotherapy planning and generates current radiotherapy planning；Calculate separately again with reference to radiotherapy planning and
Current radiotherapy planning counts the dose volume data of each organ in the dosage distribution currently delineated；Finally, will currently scheme
As, currently delineate, current radiotherapy planning is saved in data server 102；
The data transmission blocks 104, the current radiotherapy planning for confirming physics teacher are sent to the progress of scheduling software
Scheduling is sent to other radiotherapy servers progress schedulings and treatment.
Preferably, it is described with reference to radiotherapy data include but is not limited to reference picture, with reference to delineate, with reference to radiotherapy planning and ginseng
Examine dosage；Wherein, reference picture, with reference to the image once positioned before delineating, being respectively referred to reference to radiotherapy planning and reference dose, hook
Picture, radiotherapy planning and dosage.
Preferably, the automatic radiotherapy planning module 103 includes display and confirmation module.
The display and confirmation module can make physics teacher check and confirm whether currently delineating for given patient be accurate,
Check and confirm whether current radiotherapy planning correct, comparison with reference to radiotherapy planning with reference to delineate, with reference to radiotherapy planning current
It delineates, current radiotherapy planning is in the dosage and dose volume histogram currently delineated.
Embodiment 2
A kind of automatic radiotherapy planning optimization method based on the automatic radiotherapy planning system 100 in embodiment one, specifically:
(1) image for newly obtaining patient, i.e. present image upload to automatic radiotherapy planning system 100；
(2) the automatic radiotherapy planning module 103 is inquired and is obtained on data server 102 according to patient's name and ID
The reference radiotherapy data of the patient；It is described with reference to radiotherapy data include reference picture, with reference to delineate, with reference to radiotherapy planning and ginseng
Examine dosage；
Preferably, it is described with reference to radiotherapy data include but is not limited to reference picture, with reference to delineate, with reference to radiotherapy planning and ginseng
Examine dosage；Wherein, reference picture, with reference to the image once positioned before delineating, being respectively referred to reference to radiotherapy planning and reference dose, hook
Picture, radiotherapy planning and dosage；
(3) the automatic radiotherapy planning module 103 carries out 3-D image registration to reference picture and present image, and acquisition is worked as
3 D deformation vector field of the preceding image relative to reference picture；
(4) the automatic radiotherapy planning module 103 will be mapped to currently according to the 3 D deformation vector field with reference to delineating
On image, obtain currently delineate, by reference radiotherapy planning etc. centers be mapped on present image, obtain current radiotherapy
The equal centers of plan；
(5) the automatic radiotherapy planning module 103 is according to the 3 D deformation vector field in the region of interest of setting, to reference
Radiotherapy planning is modified, and current radiotherapy planning is generated；
(6) the automatic radiotherapy planning module 103, which is calculated separately, hooks with reference to radiotherapy planning and current radiotherapy planning currently
The dosage distribution drawn, counts the dose volume data of each organ；
(7) the automatic radiotherapy planning module 103 is delineated by present image, currently, current radiotherapy planning is saved in data
Server 102；
(8) currently delineating with whether current radiotherapy planning is accurate for the patient is checked and confirmed to physics teacher given patient,
Comparison with reference to radiotherapy planning with reference to delineate, with reference to radiotherapy planning currently delineate, current radiotherapy planning is currently being delineated
Dosage and dose volume histogram；
Preferably, step (8) is carried out by the display and confirmation module, and the automatic radiotherapy planning module 103 is from number
Related data is read according to server 102；
(9) if physics teacher confirms that current radiotherapy planning is correct, the current radiotherapy planning that will confirm that be sent to scheduling software into
Row scheduling；
(10) it if physics teacher does not receive current radiotherapy planning, is currently delineated or re-optimization radiotherapy meter according to reason modification
It draws, until obtaining acceptable current radiotherapy planning, confirms current radiotherapy planning, the current radiotherapy planning that will confirm that is sent to row
Journey software carries out scheduling.
Preferably, the step (2) can criticize automatically to step (7) in the case where not display interface is without manual intervention
Amount carries out.
Preferably, the 3-D image registration in the step (3), the calculating in step (6) are with reference to radiotherapy planning and currently
Radiotherapy planning carries out parallel computation in the automatic radiotherapy planning module 103 in the dosage distribution currently delineated.
Embodiment 3
On the basis of the above embodiments, the present invention further discloses a kind of automatic radiotherapy planning apparatus, the dress
It sets and includes:
At least one processor；And
Memory is stored with executable instruction on the memory, and the executable instruction is by least one described processing
Device executes, and described device is caused to realize following method:
Obtain the new image of patient, i.e. present image；
According to patient's name and ID inquiry and the reference radiotherapy data for obtaining the patient；It is described to include with reference to radiotherapy data
Reference picture, with reference to delineate, with reference to radiotherapy planning and reference dose；
3-D image registration is carried out to reference picture and present image, obtains three-dimensional of the present image relative to reference picture
Deform vector field；It according to the 3 D deformation vector field, will be mapped on present image with reference to delineating, acquisition is currently delineated, incited somebody to action
It is mapped on present image with reference to the equal centers in radiotherapy planning, obtains the equal centers of current radiotherapy planning；Root again
According to the 3 D deformation vector field in the region of interest of setting, modifies to reference radiotherapy planning and generate current radiotherapy planning；Again
It calculates separately with reference to radiotherapy planning and current radiotherapy planning in the dosage distribution currently delineated, counts the dosage body of each organ
Volume data；And it saves present image, currently delineate, current radiotherapy planning.
The invention also discloses a kind of computer-readable storage medias, including executable instruction, and described instruction is by least one
When a processor executes, following method is realized:
Obtain the new image of patient, i.e. present image；
According to patient's name and ID inquiry and the reference radiotherapy data for obtaining the patient；It is described to include with reference to radiotherapy data
Reference picture, with reference to delineate, with reference to radiotherapy planning and reference dose；
3-D image registration is carried out to reference picture and present image, obtains three-dimensional of the present image relative to reference picture
Deform vector field；It according to the 3 D deformation vector field, will be mapped on present image with reference to delineating, acquisition is currently delineated, incited somebody to action
It is mapped on present image with reference to the equal centers in radiotherapy planning, obtains the equal centers of current radiotherapy planning；Root again
According to the 3 D deformation vector field in the region of interest of setting, modifies to reference radiotherapy planning and generate current radiotherapy planning；Again
It calculates separately with reference to radiotherapy planning and current radiotherapy planning in the dosage distribution currently delineated, counts the dosage body of each organ
Volume data；And it saves present image, currently delineate, current radiotherapy planning.
For the embodiment of device and storage medium, since it is substantially similar to system embodiment, so description
It is fairly simple, related place illustrates referring to the part of system embodiment.
Embodiment 4
On the basis of embodiment 1-3, modifies to reference radiotherapy planning and generate the specific steps of current radiotherapy planning
Are as follows:
(1) obtain reference picture, with reference to delineate, with reference to radiotherapy planning, present image.
(2) image registration is carried out to present image and reference picture, generates corresponding three-dimensional and deforms vector field.
(3) it according to the 3 D deformation vector field, generates blending image identical with reference picture coverage area and retouches
It states target area and the online of organ contours delineates (that is, currently delineating)；
(4) it is determined according to the 3 D deformation vector field in the region of interest of setting described with reference to each beam in radiotherapy planning
The two dimension deformation vector field of transmitted intensity on direction.
(5) two dimension in corresponding beam direction is penetrated according to the two dimension deformation vector field of transmitted intensity in each beam direction
Line intensity distribution is deformed, and two-dimentional ray density distribution new in each beam direction is generated.
(6) according to two-dimentional ray density distribution new in each beam direction, corresponding grating and tungsten door movement number are generated
According to producing new radiotherapy planning.
Preferably, the image registration in the step (2) includes first latter two steps: (2.1) image rigid registration；
(2.2) anamorphose is registrated.
Preferably, the reference is determined according to the 3 D deformation vector field in the region of interest of setting in the step (4)
It can be different region of interest in radiotherapy planning in each beam direction during the two dimension deformation vector field of transmitted intensity
Different weights is set.
Preferably, the region of interest is target area；Further, the region of interest further includes important jeopardizing organ.
Preferably, during generating blending image in the step (3), if the coverage area of target image is less than reference
Image, then in the overlapping region of reference picture and target image, blending image by reference picture to target image deformable registration
It obtains；Region other than target image is obtained by the rigid registration of reference picture and target image.
Preferably, it while blending image is generated in the step (3) and is currently delineated, needs according to the 3 D deformation
Equal centers in reference radiotherapy planning are mapped on target image by vector field, to obtain the equal centers of new radiotherapy planning
Position.
Although the embodiments of the present invention have been disclosed as above, but its is not only in the description and the implementation listed
With it can be fully applied to various fields suitable for the present invention, for those skilled in the art, can be easily
Realize other modification, therefore without departing from the general concept defined in the claims and the equivalent scope, the present invention is simultaneously unlimited
In specific details.
Claims (10)
1. a kind of automatic radiotherapy planning system, which is characterized in that the system comprises data reception module, data server, from
Dynamic radiotherapy planning module, data transmission blocks.
2. a kind of automatic radiotherapy planning system according to claim 1, which is characterized in that
The data reception module for receiving patient with reference to radiotherapy data and present image, and is saved into data service
Device；Wherein,
It is described with reference to radiotherapy data include reference picture, with reference to delineate, with reference to radiotherapy planning and reference dose；The present image
For the image newly obtained after patient's reorientation；
The data server, for storing all medical datas of patient；
The automatic radiotherapy planning module, goes after data reception module receives present image automatically according to patient's name and ID
The reference radiotherapy data of the patient are inquired and obtained on data server；And three-dimensional figure is carried out to reference picture and present image
As registration, 3 D deformation vector field of the present image relative to reference picture is obtained；It, will and according to the 3 D deformation vector field
It is mapped on present image with reference to delineating, acquisition is currently delineated, and the equal centers in reference radiotherapy planning are mapped to currently
On image, the equal centers of current radiotherapy planning are obtained；It is right further according to the 3 D deformation vector field in the region of interest of setting
It modifies with reference to radiotherapy planning and generates current radiotherapy planning；It calculates separately and is working as with reference to radiotherapy planning and current radiotherapy planning again
Before delineate dosage distribution, count the dose volume data of each organ；Finally, by present image, currently delineating, currently putting
Treatment plan is saved in data server；
The data transmission blocks, the current radiotherapy planning for confirming physics teacher are sent to scheduling software and carry out scheduling or hair
It is sent to other radiotherapy servers and carries out scheduling and treatment.
3. a kind of automatic radiotherapy planning system according to claim 2, which is characterized in that the automatic radiotherapy planning module
Including display and confirmation module；
The display and confirmation module can make physics teacher check and confirm whether currently delineating for given patient be accurate, checks
With confirm whether current radiotherapy planning correct, comparison with reference to radiotherapy planning with reference to delineate, with reference to radiotherapy planning currently delineate,
Current radiotherapy planning is in the dosage and dose volume histogram currently delineated.
4. a kind of automatic radiotherapy planning system according to claim 2, which is characterized in that reference picture, with reference to delineating, join
Examine radiotherapy planning and reference dose respectively refer to before once position image, delineate, radiotherapy planning and dosage.
5. a kind of automatic radiotherapy planning system according to claim 2, which is characterized in that the automatic radiotherapy planning module
It modifies to reference radiotherapy planning and generates the specific steps of current radiotherapy planning are as follows:
(1) present image is generated as and reference picture by the 3 D deformation vector field according to present image relative to reference picture
The identical blending image of coverage area；
(2) it is determined according to the 3 D deformation vector field in the region of interest of setting described with reference to each beam direction in radiotherapy planning
The two dimension deformation vector field of upper transmitted intensity；
(3) the two dimension deformation vector field according to transmitted intensity in each beam direction is strong to the two-dimentional ray in corresponding beam direction
Degree distribution is deformed, and two-dimentional ray density distribution new in each beam direction is generated；
(4) according to two-dimentional ray density distribution new in each beam direction, corresponding grating and tungsten door exercise data are generated, i.e.,
Obtain new radiotherapy planning.
6. a kind of automatic radiotherapy planning system according to claim 5, which is characterized in that the sense in the step (2) is emerging
Interesting area includes target area and jeopardizes organ.
7. a kind of automatic radiotherapy planning system according to claim 6, which is characterized in that in the step (2) target area and
Jeopardize power of the organ when determining that the two dimension with reference to transmitted intensity in beam direction each in radiotherapy planning deforms vector field
Value is different.
8. based on a kind of application method of automatic radiotherapy planning system described in claim 1, which is characterized in that the method packet
It includes:
(1) image for newly obtaining patient, i.e. present image upload to automatic radiotherapy planning system；
(2) the automatic radiotherapy planning module inquires on data server and obtains the patient's according to patient's name and ID
With reference to radiotherapy data；It is described with reference to radiotherapy data include reference picture, with reference to delineate, with reference to radiotherapy planning and reference dose；
(3) the automatic radiotherapy planning module carries out 3-D image registration to reference picture and present image, obtains present image
3 D deformation vector field relative to reference picture；
(4) the automatic radiotherapy planning module will be mapped on present image according to the 3 D deformation vector field with reference to delineating,
Obtain currently delineate, by reference radiotherapy planning etc. centers be mapped on present image, obtain current radiotherapy planning
Equal centers；
(5) the automatic radiotherapy planning module is according to the 3 D deformation vector field in the region of interest of setting, to reference radiotherapy meter
It draws and modifies, generate current radiotherapy planning；
(6) the automatic radiotherapy planning module is calculated separately with reference to radiotherapy planning and current radiotherapy planning in the agent currently delineated
Amount distribution, counts the dose volume data of each organ；
(7) the automatic radiotherapy planning module is delineated by present image, currently, current radiotherapy planning is saved in data server；
(8) physics teacher given patient checks and confirms that the patient's currently delineates the comparison with whether current radiotherapy planning is accurate
With reference to radiotherapy planning with reference to delineate, with reference to radiotherapy planning currently delineate, current radiotherapy planning is in the dosage currently delineated
And dose volume histogram；
(9) if physics teacher confirms that current radiotherapy planning is correct, the current radiotherapy planning that will confirm that is sent to scheduling software and is arranged
Journey；
(10) it if physics teacher does not receive current radiotherapy planning, is currently delineated or re-optimization radiotherapy planning according to reason modification,
Until obtaining acceptable current radiotherapy planning, current radiotherapy planning is confirmed, the current radiotherapy planning that will confirm that is sent to scheduling
Software carries out scheduling.
9. a kind of automatic radiotherapy planning apparatus, which is characterized in that described device includes:
At least one processor；And
Memory is stored with executable instruction on the memory, and the executable instruction is held by least one described processor
Row causes described device to realize following method:
Obtain the new image of patient, i.e. present image；
According to patient's name and ID inquiry and the reference radiotherapy data for obtaining the patient；It is described to include reference with reference to radiotherapy data
Image, with reference to delineate, with reference to radiotherapy planning and reference dose；
3-D image registration is carried out to reference picture and present image, obtains 3 D deformation of the present image relative to reference picture
Vector field；According to the 3 D deformation vector field, will be mapped on present image with reference to delineating, acquisition is currently delineated, will be referred to
Equal centers in radiotherapy planning are mapped on present image, obtain the equal centers of current radiotherapy planning；Further according to setting
3 D deformation vector field in fixed region of interest, modifies to reference radiotherapy planning and generates current radiotherapy planning；Distinguish again
It calculates with reference to radiotherapy planning and current radiotherapy planning in the dosage distribution currently delineated, counts the dose volume number of each organ
According to；And it saves present image, currently delineate, current radiotherapy planning.
10. a kind of computer-readable storage media, including executable instruction, when described instruction is executed by least one processor,
Realize following method:
Obtain the new image of patient, i.e. present image；
According to patient's name and ID inquiry and the reference radiotherapy data for obtaining the patient；It is described to include reference with reference to radiotherapy data
Image, with reference to delineate, with reference to radiotherapy planning and reference dose；
3-D image registration is carried out to reference picture and present image, obtains 3 D deformation of the present image relative to reference picture
Vector field；According to the 3 D deformation vector field, will be mapped on present image with reference to delineating, acquisition is currently delineated, will be referred to
Equal centers in radiotherapy planning are mapped on present image, obtain the equal centers of current radiotherapy planning；Further according to setting
3 D deformation vector field in fixed region of interest, modifies to reference radiotherapy planning and generates current radiotherapy planning；Distinguish again
It calculates with reference to radiotherapy planning and current radiotherapy planning in the dosage distribution currently delineated, counts the dose volume number of each organ
According to；And it saves present image, currently delineate, current radiotherapy planning.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910106475.1A CN109872804B (en) | 2019-02-02 | 2019-02-02 | Automatic radiotherapy planning system and using method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910106475.1A CN109872804B (en) | 2019-02-02 | 2019-02-02 | Automatic radiotherapy planning system and using method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109872804A true CN109872804A (en) | 2019-06-11 |
| CN109872804B CN109872804B (en) | 2022-04-29 |
Family
ID=66918557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910106475.1A Active CN109872804B (en) | 2019-02-02 | 2019-02-02 | Automatic radiotherapy planning system and using method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109872804B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112037886A (en) * | 2020-11-04 | 2020-12-04 | 平安科技（深圳）有限公司 | Radiotherapy plan making device, method and storage medium |
| WO2021143019A1 (en) * | 2020-01-14 | 2021-07-22 | 平安科技（深圳）有限公司 | Image search method and apparatus based on artificial intelligence, device, and medium |
| CN114864070A (en) * | 2022-04-28 | 2022-08-05 | 福建自贸试验区厦门片区Manteia数据科技有限公司 | Radiotherapy information management system |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110026794A1 (en) * | 2009-07-29 | 2011-02-03 | Siemens Corporation | Deformable 2D-3D Registration of Structure |
| CN102306239A (en) * | 2011-07-22 | 2012-01-04 | 李宝生 | Method for evaluating and optimizing radiotherapy dose based on cone beam CT (Computer Tomography) image CT value correction technology |
| CN103761441A (en) * | 2014-01-26 | 2014-04-30 | 深圳市医诺智能科技发展有限公司 | Verification method and device for radiotherapy plan |
| CN104117151A (en) * | 2014-08-12 | 2014-10-29 | 章桦 | Optimization method of online self-adaption radiotherapy plan |
| CN104252580A (en) * | 2014-09-24 | 2014-12-31 | 山东省肿瘤医院 | Method for migrating radiotherapy plans on Pinnacle therapy planning system |
| CN105825073A (en) * | 2016-06-17 | 2016-08-03 | 张家港赛提菲克医疗器械有限公司 | Online radiotherapy plan quality control software |
| US20170178349A1 (en) * | 2015-12-18 | 2017-06-22 | The Johns Hopkins University | Method for deformable 3d-2d registration using multiple locally rigid registrations |
-
2019
- 2019-02-02 CN CN201910106475.1A patent/CN109872804B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110026794A1 (en) * | 2009-07-29 | 2011-02-03 | Siemens Corporation | Deformable 2D-3D Registration of Structure |
| CN102306239A (en) * | 2011-07-22 | 2012-01-04 | 李宝生 | Method for evaluating and optimizing radiotherapy dose based on cone beam CT (Computer Tomography) image CT value correction technology |
| CN103761441A (en) * | 2014-01-26 | 2014-04-30 | 深圳市医诺智能科技发展有限公司 | Verification method and device for radiotherapy plan |
| CN104117151A (en) * | 2014-08-12 | 2014-10-29 | 章桦 | Optimization method of online self-adaption radiotherapy plan |
| CN104252580A (en) * | 2014-09-24 | 2014-12-31 | 山东省肿瘤医院 | Method for migrating radiotherapy plans on Pinnacle therapy planning system |
| US20170178349A1 (en) * | 2015-12-18 | 2017-06-22 | The Johns Hopkins University | Method for deformable 3d-2d registration using multiple locally rigid registrations |
| CN105825073A (en) * | 2016-06-17 | 2016-08-03 | 张家港赛提菲克医疗器械有限公司 | Online radiotherapy plan quality control software |
Non-Patent Citations (1)
| Title |
|---|
| 梁月强: "图像引导放射治疗若干关键问题的研究", 《中国博士学位论文全文数据库 信息科技辑》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021143019A1 (en) * | 2020-01-14 | 2021-07-22 | 平安科技（深圳）有限公司 | Image search method and apparatus based on artificial intelligence, device, and medium |
| CN112037886A (en) * | 2020-11-04 | 2020-12-04 | 平安科技（深圳）有限公司 | Radiotherapy plan making device, method and storage medium |
| CN114864070A (en) * | 2022-04-28 | 2022-08-05 | 福建自贸试验区厦门片区Manteia数据科技有限公司 | Radiotherapy information management system |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109872804B (en) | 2022-04-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104117151B (en) | Optimization method of online self-adaption radiotherapy plan | |
| Aird et al. | CT simulation for radiotherapy treatment planning | |
| CN109872804A (en) | A kind of automatic radiotherapy planning system and its application method | |
| US10864382B2 (en) | System and method for radiation therapy treatment planning | |
| EP2994195B1 (en) | Interactive dose gradient based optimization technique to control imrt delivery complexity | |
| WO2020256750A1 (en) | Predicting radiotherapy control points using projection images | |
| US20220180524A1 (en) | Automatic contour adaptation using neural networks | |
| CN114796891A (en) | Radiotherapy system | |
| US10710354B2 (en) | Data driven framework for optimizing artificial organ printing and scaffold selection for regenerative medicine | |
| CN104815392B (en) | A kind of interactive radiotherapy treatment planning system optimization system | |
| CN104636618B (en) | Radiotherapy planning system | |
| CN109771850A (en) | A kind of adaptive radiotherapy planning modification method | |
| EP4230261A1 (en) | Dose volume histogram optimization based on quantile regression | |
| JP6971054B2 (en) | How to create treatment planning equipment, programs and treatment plans | |
| EP4341905A1 (en) | Iterative image reconstruction | |
| US11989851B2 (en) | Deformable image registration using deep learning | |
| CN110465004A (en) | A kind of generation method of cloud radiotherapy treatment planning system and radiotherapy treatment planning | |
| US20230285776A1 (en) | Dynamic adaptation of radiotherapy treatment plans | |
| CN107341791A (en) | A kind of hook Target process, apparatus and system based on mixed reality | |
| JP7502566B2 (en) | Automatic treatment plan generation with dose prediction and robust dose mimicking | |
| CN116612853B (en) | Radiotherapy verification plan dose generation method, radiotherapy verification plan dose generation system, electronic equipment and storage medium | |
| EP3751524A1 (en) | Method, computer program product and computer system for providing an approximate image | |
| Schmidt et al. | Deforming to Best Practice: Key considerations for deformable image registration in radiotherapy | |
| CN115300811A (en) | Dose distribution determination method and device based on machine learning | |
| CN117257335A (en) | Equipment control method, device, equipment, medium and control system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20191015 Address after: 215000 room 401B, building a, emerging industry education center, Zhangjiagang Free Trade Zone, Suzhou City, Jiangsu Province Applicant after: Zhangjiagang Medical Instrument Co., Ltd. Address before: 200433, room 3, building 200, No. 107-4 East National Road, Shanghai, Yangpu District Applicant before: Shanghai Satifike Medical Apparatus And Instruments Co., Ltd. |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant |