CN109872351A - A kind of medical figure registration and three-dimensional reconstruction system and method - Google Patents
A kind of medical figure registration and three-dimensional reconstruction system and method Download PDFInfo
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- CN109872351A CN109872351A CN201910203647.7A CN201910203647A CN109872351A CN 109872351 A CN109872351 A CN 109872351A CN 201910203647 A CN201910203647 A CN 201910203647A CN 109872351 A CN109872351 A CN 109872351A
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Abstract
The invention discloses a kind of medical figure registrations and three-dimensional reconstruction system and method, belong to technical field of medical image processing.Medical figure registration and three-dimensional reconstruction system of the invention includes user log-in block, three-dimensional reconstruction module, image registration module and file access module, the user log-in block includes registering unit, for user's logon rights to be arranged for system, three-dimensional reconstruction module for being shown the image sequence read in file one by one, for allowing, user reads selected floating image to image registration module from file and reference picture is registrated, blending image and relevant parameter after output registration, file access module is used for the access to user's login account and password and image.The medical figure registration and three-dimensional reconstruction system of the invention are capable of providing apparent, comprehensive, intuitive displaying inside of human body internal organs information, to make accurately judgement and more perfect therapeutic scheme, have good application value.
Description
Technical field
The present invention relates to technical field of medical image processing, specifically provide a kind of medical figure registration and three-dimensional reconstruction system
And method.
Background technique
With the rapid development of computer technology and medical imaging technology, the medical image of multiple modalities occurs in succession, is
Clinical diagnosis provides data abundant.Since the difference of image-forming principle and imaging device causes a variety of imaging patterns simultaneously
It deposits, according to the difference of their provided information, medical image can be divided into anatomical structure image and function image two major classes.Its
In, anatomical structure image provides human anatomic structure information abundant, and function image then provides related bodily fuctions' metabolism
The information of aspect.
The imaging pattern of medical image is different, and the information for the related internal organs for causing it can be provided is also different.For example, calculating
The resolution ratio of machine tomographic imaging (CT) image is very strong, and the imaging slitted to bone is very clear, can be very good to realize the standard to lesion
Determine position, it is still, relatively fuzzyyer to the imaging of the lesser soft tissue of tissue density's difference；In positron emission tomography
(PET) in image, the metabolism and blood flow situation of human body different tissues organ be can clearly be observed that, these
Bodily fuctions' information all provides foundation for clinical diagnosis.But since image resolution ratio is lower, Yao Congzhong is accurately solved
It is very difficult for cuing open structure, and is not easy to make the boundary of respective organization and organ accurate judgement.Sometimes, single
The image of mode can not provide enough information as diagnosis basis for the clinical diagnosis of doctor.Such as the mistake in radiotherapy
Cheng Zhong: patient, which can always have autonomous or involuntary act, to lead to the histoorgan of human body deformation occurs, so as to cause mesh
The target area for marking tumour generates a degree of displacement.Such case may result in serious consequence: the tumour near target area does not have
It is destroyed, normal institutional framework is but by rays break.Can be by using image registration algorithm, correcting parameter adjusts
The displacement that the distribution of dosage needed for angle, adjustment for the treatment of target tumor generates to compensate the movement because of patient.
In traditional clinical diagnosis, doctor can only be scanned tomography locating for focal area, and obtain to express
The two-dimensional ct image of a certain section information.Since two-dimensional ct image lacks enough visual data information, doctor is being diagnosed
In will necessarily adulterate subjective judgement so that accurate diagnostic result cannot be provided and influence the effect of clinical treatment.Therefore, it is
The accuracy of medical diagnosis and treatment planning and scientific is improved, is needed two-dimensional ct image sequence transitions for intuitive
The image of stereoscopic effect, shows the three-dimensional structure and form of lesion, to obtain anatomical information, and carries out for clinician
Virtual operation provides visual interactive means.In the prior art, three-dimensional reconstruction is mostly iso-surface patch, and iso-surface patch is actually to show
To sense of reality projection of the three-dimension object on two-dimensional surface, just as when visual angle is located at certain point, from the point to three-dimension object into
Row " photograph ", the three-dimension object image that phase on piece is shown.As shown in Figure 1, detailed process is as follows: (1) by registration and interpolation after,
Basic three-dimensional data needed for iso-surface patch is established, the gray threshold of the selected contour surface shown as surface.(2) close to upper and lower
Corresponding four pixels of two layer datas constitute a cube, or corresponding at a voxel.(3) totally 8 vertex of voxel are pressed
Classify according to the contour surface threshold value being previously obtained, than or equal to threshold value, then the internal point of contour surface is can be regarded as on vertex；Less than threshold
Value, the external point of contour surface is can be regarded as on vertex.(4) the binary coding concordance list for representing vertex inside and outside state is generated.(5)
It is moved to next cube, repeats above step.(6) the structure lookup table that a length is 256 is inquired with this concordance list, obtained
To the specific topology status (configuration) of profile (contour surface) and cubic space relationship.(7) true by linear interpolation according to configuration
Determine the triangular plate apex coordinate that contour surface intersects with cube, obtains the specific location of profile.Surface rendering techniques need intermediate collection
Pel is closed, process is cumbersome, and efficiency is lower.
Summary of the invention
Technical assignment of the invention be in view of the above problems, provide one kind be capable of providing it is apparent, comprehensive, intuitive
Displaying inside of human body internal organs information, thus make accurately judgement and more perfect therapeutic scheme medical figure registration and three
Tie up reconstructing system.
The further technical assignment of the present invention is to provide a kind of medical figure registration and three-dimensional rebuilding method.
To achieve the above object, the present invention provides the following technical scheme that
A kind of medical figure registration and three-dimensional reconstruction system, including user log-in block, three-dimensional reconstruction module, image registration
Module and file access module, the user log-in block include registering unit, are used to be system setting user's logon rights, three
Dimension rebuilds module for being shown the image sequence read in file one by one, and image registration module is for allowing user from text
Selected floating image is read in part and reference picture is registrated, blending image and relevant parameter after output registration, file access
Module is used for the access to user's login account and password and image.
User is arranged for the system to log in, enables the talent for only possessing permission to log in the system, does not allow not weigh
The people of limit accesses to system.Operations all later will be carried out according under conditions of having logged on.New user can be into
Row registration obtains logon rights.Existing account can modify to password according to corresponding account number cipher.
Data used in this system are maintained in file access module, support local access.Ordinary user's logon account and
Administrator's account is stored in .mat file, and the SUV image of CT tomographic sequence and PET image sequence and corresponding conversion is equal
There are under the file of respective paths, convenient reading.
Preferably, being equipped with account management unit in the user log-in block, administrator passes through account management unit pair
System is managed and searching user's information, including registration information and the last login time information, deletes account
With modification registration information.
Administrator's Account Logon can be managed to system and searching user's information, including registration information and the last time
Login time information can be deleted user account and be modified registration information.
Preferably, the three-dimensional reconstruction module is volume rendering three-dimensional reconstruction, two on screen are generated by 3 d data field
Image is tieed up, the general image of three-dimensional data is generated, using voxel as basic unit, directly displays image.
Three-dimensional reconstruction is carried out using ray casting volume rendering algorithm in the present invention.
Preferably, shown image registration module includes the Powell algorithm of Rigid Registration and the ant group algorithm of elastic registrating
With the improvement of ant group algorithm, single mode image and multimode image registering, blending image and relevant parameter after output registration are selected.
Preferably, the Powell algorithm each round iteration is made of n+1 linear search, in each iteration of algorithm
In the process, first successively along known n direction search for, obtain a desired positions, along current iteration initial point with this most
The direction of better line scans for, and acquires the most better of this stage, then before being replaced with the last direction of search n direction it
One, start the iteration in next stage.
A kind of medical figure registration and three-dimensional rebuilding method, the logging in system by user with logon rights, will be from file
The tomographic sequence of reading is shown one by one, and image is all converted to corresponding SUV image, and show respectively, carries out body
Drawing three-dimensional is rebuild and is shown the image completed is rebuild, and user selectes floating image and reference picture is calculated from Powell
The improvement selection of method, ant group algorithm and ant group algorithm is registrated, output registration image and blending image.
Preferably, user's login account is completed with password and image by file access module in this method.
Preferably, the three-dimensional reconstruction module is volume rendering three-dimensional reconstruction, two on screen are generated by 3 d data field
Image is tieed up, the general image of three-dimensional data is generated, using voxel as basic unit, directly displays image.
Preferably, the Powell algorithm each round iteration is made of n+1 linear search, in each iteration of algorithm
In the process, first successively along known n direction search for, obtain a desired positions, along current iteration initial point with this most
The direction of better line scans for, and acquires the most better of this stage, then before being replaced with the last direction of search n direction it
One, start the iteration in next stage.
Compared with prior art, medical figure registration of the invention and three-dimensional rebuilding method have beneficial effect following prominent
Fruit: in clinical diagnosis, having reconstructed has relief 3 D medical figure for the medical figure registration and three-dimensional rebuilding method
Picture, the structural information of more intuitive display lesion, it is more objective effectively to lesion progress data to enable the clinician to
Processing and analysis, obtain more accurate diagnostic result.Meanwhile other simulated operation functions can also be carried out to image, such as revolve
Turn, cutting, three-dimension interaction, scaling etc., the more intuitive internal organizational structure for showing lesion complexity, and with registration accuracy
The features such as height, strong robustness, has good application value.
Detailed description of the invention
Fig. 1 is the three-dimensional reconstruction flow chart of iso-surface patch in the prior art；
Fig. 2 is the topological diagram of medical figure registration and three-dimensional reconstruction system of the present invention；
Fig. 3 is the flow chart of the Powell algorithm of medical figure registration and three-dimensional rebuilding method of the present invention.
Specific embodiment
Below in conjunction with drawings and examples, to medical figure registration and three-dimensional reconstruction system of the invention and method make into
One step is described in detail.
Embodiment
Single modality images refer to the image obtained with same imaging technique in the present invention；What multi-modality images referred to
It is the image obtained with different imaging techniques.
As shown in Fig. 2, medical figure registration and three-dimensional reconstruction system of the invention, including user log-in block, Three-dimensional Gravity
Model block, image registration module and file access module.
User log-in block includes registering unit and account management unit.
Registering unit is used to that user's logon rights to be arranged for system, enables the talent for only possessing permission to log in this and is
System, does not allow the people of not permission to access system.All operations will be carried out according under conditions of having logged on.Newly
User can carry out registration and obtain logon rights.Existing account can modify to password according to corresponding account number cipher.
Administrator is managed and searching user's information system by account management unit, including registration information and recently
Login time information, is deleted account and is modified registration information.
Three-dimensional reconstruction module for being shown the image sequence read in file one by one.Volume drawing is projected using light
Algorithm carries out three-dimensional reconstruction.Three-dimensional reconstruction module is volume rendering three-dimensional reconstruction, generates the X-Y scheme on screen by 3 d data field
Picture generates the general image of three-dimensional data, using voxel as basic unit, directly displays image.
Image registration module is selected floating image and reference picture and is registrated for allowing user to read from file, defeated
Blending image and relevant parameter after being registrated out.Image registration module includes Powell algorithm and the ant of elastic registrating of Rigid Registration
The improvement of group algorithm and ant group algorithm selects single mode image and multimode image registering, blending image and corresponding ginseng after output registration
Number.As shown in figure 3, Powell algorithm each round iteration is made of n+1 linear search, in each iterative process of algorithm,
It is first successively searched for along known n direction, obtains a desired positions, along the initial point and the most better line of current iteration
Direction scan for, acquire the most better of this stage, then one of n direction before being replaced with the last direction of search, beginning
The iteration in next stage.
File access module is used for the access to user's login account and password and image.Data used in the system save
In file access module, local access is supported.Ordinary user's logon account and administrator's account are stored in .mat file, CT
Tomographic sequence and the SUV image of PET image sequence and corresponding conversion exist under the file of respective paths, facilitate reading
It takes.
Of the invention a kind of medical figure registration and three-dimensional rebuilding method, the logging in system by user with logon rights will
The tomographic sequence read in from file is shown one by one, and image is all converted to corresponding SUV image, and show respectively
Show, carry out volume rendering three-dimensional reconstruction simultaneously and will rebuild the image completed to show, user select floating image and reference picture from
The improvement selection of Powell algorithm, ant group algorithm and ant group algorithm is registrated, output registration image and blending image.Powell
Algorithm each round iteration is made of n+1 linear search, in each iterative process of algorithm, first successively along known n
Direction search, obtains a desired positions, the direction along the most better line of initial point and this of current iteration scans for, and acquires
Most better, then one of the n direction before being replaced with the last direction of search in this stage, starts the iteration in next stage.
Embodiment described above, the only present invention more preferably specific embodiment, those skilled in the art is at this
The usual variations and alternatives carried out within the scope of inventive technique scheme should be all included within the scope of the present invention.
Claims (9)
1. a kind of medical figure registration and three-dimensional reconstruction system, it is characterised in that: modeled including user log-in block, Three-dimensional Gravity
Block, image registration module and file access module, the user log-in block include registering unit, for user to be arranged for system
Logon rights, for being shown the image sequence read in file one by one, image registration module is used for three-dimensional reconstruction module
Permission user reads selected floating image from file and reference picture is registrated, blending image and accordingly ginseng after output registration
Number, file access module are used for the access to user's login account and password and image.
2. medical figure registration according to claim 1 and three-dimensional reconstruction system, it is characterised in that: the user logs in mould
Account management unit is equipped in block, administrator is managed by account management unit to system and searching user's information, including
Registration information and the last login time information, are deleted account and are modified registration information.
3. medical figure registration according to claim 1 or 2 and three-dimensional reconstruction system, it is characterised in that: the Three-dimensional Gravity
Block is modeled as volume rendering three-dimensional reconstruction, the two dimensional image on screen is generated by 3 d data field, generates the overall diagram of three-dimensional data
Picture directly displays image using voxel as basic unit.
4. medical figure registration according to claim 3 and three-dimensional reconstruction system, it is characterised in that: shown image registration mould
Block includes the improvement of the Powell algorithm of Rigid Registration and the ant group algorithm and ant group algorithm of elastic registrating, select single mode image and
Multimode image registering, blending image and relevant parameter after output is registrated.
5. medical figure registration according to claim 4 and three-dimensional reconstruction system, it is characterised in that: the Powell algorithm
Each round iteration is made of n+1 linear search, in each iterative process of algorithm, first successively along known n direction
Search, obtains a desired positions, the direction along the most better line of initial point and this of current iteration scans for, and acquires this
Most better, then one of the n direction before being replaced with the last direction of search in stage, starts the iteration in next stage.
6. a kind of medical figure registration and three-dimensional rebuilding method, it is characterised in that: in this method, the user with logon rights is stepped on
Recording system shows the tomographic sequence read in from file one by one, and image is all converted to corresponding SUV image,
And show, carry out volume rendering three-dimensional reconstruction and shown the image completed is rebuild respectively, user selectes floating image and ginseng
It examines image to be registrated from the improvement of Powell algorithm, ant group algorithm and ant group algorithm selection, output registration image and fusion figure
Picture.
7. medical figure registration according to claim 6 and three-dimensional rebuilding method, it is characterised in that: user steps in this method
Record account is completed with password and image by file access module.
8. medical figure registration according to claim 6 or 7 and three-dimensional rebuilding method, it is characterised in that: the Three-dimensional Gravity
Block is modeled as volume rendering three-dimensional reconstruction, the two dimensional image on screen is generated by 3 d data field, generates the overall diagram of three-dimensional data
Picture directly displays image using voxel as basic unit.
9. medical figure registration according to claim 8 and three-dimensional rebuilding method, it is characterised in that: the Powell algorithm
Each round iteration is made of n+1 linear search, in each iterative process of algorithm, first successively along known n direction
Search, obtains a desired positions, the direction along the most better line of initial point and this of current iteration scans for, and acquires this
Most better, then one of the n direction before being replaced with the last direction of search in stage, starts the iteration in next stage.
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