CN109862928B - 自动药物递送系统和方法 - Google Patents

自动药物递送系统和方法 Download PDF

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Publication number
CN109862928B
CN109862928B CN201780046833.3A CN201780046833A CN109862928B CN 109862928 B CN109862928 B CN 109862928B CN 201780046833 A CN201780046833 A CN 201780046833A CN 109862928 B CN109862928 B CN 109862928B
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CN
China
Prior art keywords
actuator
controller
syringe
drug delivery
sensor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201780046833.3A
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English (en)
Chinese (zh)
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CN109862928A (zh
Inventor
P·阿南德
A·阿祖曼德
M·布罗菲
A·伊斯特
G·R·埃贝尔
德普阿琼·辛格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yakana Therapeutics Co ltd
Alcyone Therapeutics Inc
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Yakana Therapeutics Co ltd
Alcyone Lifesciences Inc
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Publication of CN109862928A publication Critical patent/CN109862928A/zh
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14546—Front-loading type injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14513—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3344—Measuring or controlling pressure at the body treatment site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1003—Spinal column
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/04—Heartbeat characteristics, e.g. ECG, blood pressure modulation
    • A61M2230/06—Heartbeat rate only
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2046—Media being expelled from injector by gas generation, e.g. explosive charge

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
CN201780046833.3A 2016-07-29 2017-07-28 自动药物递送系统和方法 Active CN109862928B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662368797P 2016-07-29 2016-07-29
US62/368797 2016-07-29
US201662369361P 2016-08-01 2016-08-01
US62/369361 2016-08-01
PCT/US2017/044286 WO2018022955A1 (en) 2016-07-29 2017-07-28 Automated drug delivery systems and methods

Publications (2)

Publication Number Publication Date
CN109862928A CN109862928A (zh) 2019-06-07
CN109862928B true CN109862928B (zh) 2022-06-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780046833.3A Active CN109862928B (zh) 2016-07-29 2017-07-28 自动药物递送系统和方法

Country Status (7)

Country Link
US (2) US10828424B2 (enExample)
EP (1) EP3490638A4 (enExample)
JP (2) JP2019521809A (enExample)
CN (1) CN109862928B (enExample)
AU (2) AU2017302599B2 (enExample)
CA (1) CA3032123A1 (enExample)
WO (1) WO2018022955A1 (enExample)

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US8062864B2 (en) * 2007-05-21 2011-11-22 Alderbio Holdings Llc Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies
CN104936639A (zh) * 2013-01-29 2015-09-23 赛诺菲-安万特德国有限公司 电子模块和药物输送装置
WO2016183123A1 (en) * 2015-05-11 2016-11-17 Alcyone Lifesciences, Inc. Drug delivery systems and methods
DE102015118011A1 (de) * 2015-10-22 2017-04-27 Human Med Ag Vorrichtung zur Transplantation von Körperfett
GB2556616B (en) * 2016-07-21 2019-09-25 Cipher Surgical Ltd Scope assembly
US10675438B2 (en) 2017-11-15 2020-06-09 Alcyone Lifesciences, Inc. Therapy specific, pre-programmed auto injection device
WO2019209800A1 (en) 2018-04-23 2019-10-31 The Trustees Of Columbia University In The City Of New York Fluid responsive devices and methods
US11480561B2 (en) 2018-08-14 2022-10-25 Cardiac Pacemakers, Inc. Systems and methods for monitoring immunotherapy toxicity
US10940290B2 (en) 2018-08-27 2021-03-09 Alcyone Lifesciences, Inc. Fluid delivery systems and methods
US10926024B2 (en) 2018-10-04 2021-02-23 Corvictus Llc Emergency medical intervention device
EP3903859B1 (en) * 2018-12-27 2025-09-24 Daicel Corporation Needleless injector
US12048830B2 (en) * 2019-03-07 2024-07-30 Kpr U.S., Llc Delivery of fluid from a syringe
US10646660B1 (en) * 2019-05-16 2020-05-12 Milestone Scientific, Inc. Device and method for identification of a target region
DE102019123870A1 (de) * 2019-09-05 2021-03-11 Pharmpur Gmbh Stiftartiges Spritzensystem
US11738154B2 (en) * 2019-09-11 2023-08-29 Altaviz, Llc Micro-volume injectors with dose guidance and methods for use
FR3109318B1 (fr) * 2020-04-15 2023-11-10 Syrengy Seringue d’injection
DE202020106870U1 (de) * 2020-11-30 2022-03-03 Pharmpur Gmbh Stiftartige Spritzenvorrichtung und Spritzensystem
CN112957566A (zh) * 2021-01-28 2021-06-15 四川省肿瘤医院 一种脉冲式注射器助力装置
EP4326365A4 (en) * 2021-05-19 2025-03-12 Alcyone Therapeutics, Inc. FLUID DELIVERY SYSTEMS AND TREATMENT METHODS
US20250000495A1 (en) * 2021-11-15 2025-01-02 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca Syringe driving systems
WO2024019938A1 (en) 2022-07-18 2024-01-25 Medphlow, Llc Integrated cartridge assembly for administration of drugs

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WO2008009143A1 (en) * 2006-07-17 2008-01-24 Medmix Systems Ag Dispensing appliance for a multiple cartridge
CN103338799A (zh) * 2010-11-29 2013-10-02 赛诺菲-安万特德国有限公司 药物递送装置
WO2016026573A2 (de) * 2014-08-18 2016-02-25 Edwin Kreuzeder Vorrichtung zum auspressen von viskosen massen aus behältern

Also Published As

Publication number Publication date
CN109862928A (zh) 2019-06-07
JP2022089998A (ja) 2022-06-16
EP3490638A1 (en) 2019-06-05
JP2019521809A (ja) 2019-08-08
US20180028761A1 (en) 2018-02-01
US20210052820A1 (en) 2021-02-25
CA3032123A1 (en) 2018-02-01
US10828424B2 (en) 2020-11-10
EP3490638A4 (en) 2020-01-22
WO2018022955A1 (en) 2018-02-01
AU2017302599B2 (en) 2022-09-01
AU2017302599A1 (en) 2019-01-24
AU2022279517A1 (en) 2023-02-02

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