CN109846842A - A kind of pet composite tablet and preparation method thereof - Google Patents

A kind of pet composite tablet and preparation method thereof Download PDF

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Publication number
CN109846842A
CN109846842A CN201910095782.4A CN201910095782A CN109846842A CN 109846842 A CN109846842 A CN 109846842A CN 201910095782 A CN201910095782 A CN 201910095782A CN 109846842 A CN109846842 A CN 109846842A
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CN
China
Prior art keywords
parts
composite tablet
starch
pet
preparation
Prior art date
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Pending
Application number
CN201910095782.4A
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Chinese (zh)
Inventor
冯建国
张运林
董孟迁
黄小艳
蒋玉国
康利均
周祖兰
徐亮
杜连菊
敬圣
夏先鹏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SICHUAN TAIXIN ANIMAL PHARMACEUTICAL CO Ltd
Original Assignee
SICHUAN TAIXIN ANIMAL PHARMACEUTICAL CO Ltd
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Priority to CN201910095782.4A priority Critical patent/CN109846842A/en
Publication of CN109846842A publication Critical patent/CN109846842A/en
Pending legal-status Critical Current

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  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides a kind of pet composite tablets and preparation method thereof, the composite tablet is made of following components in parts by mass: 18 parts~22 parts of Pyrantel Pamoate, 8 parts~13 parts of praziquantel, 40 parts~50 parts of powdered beef, 15 parts~25 parts of starch, 1 part~10 parts of starch slurry, 1 part~2 parts of dextrin, 0.5 part~1 part of magnesium stearate.The preparation method comprises the following steps: in parts by mass, 18 parts~22 parts of Pyrantel Pamoate, 8 parts~13 parts of praziquantel, 40 parts~50 parts of powdered beef, 15 parts~25 parts of starch being mixed, softwood is obtained;0.5 part~1 part of magnesium stearate and 1 part~2 parts dextrin is added in granulation, whole grain, mixes, and tabletting obtains composite tablet.Preparation method simple process and low cost of the invention can be adapted for heavy industrialization generation, and the composite tablet smooth appearance being prepared is disintegrated rapidly after taking, and anthelminthic effect is good.

Description

A kind of pet composite tablet and preparation method thereof
Technical field
The present invention relates to pet medication preparation technical fields, more particularly, be related to a kind of pet composite tablet and its Preparation method.
Background technique
With the continuous improvement of people's living standards, Medical pet technology is grown rapidly, the people for raising pet becomes It is more and more, but the probability that pet is fallen ill is still larger, especially for the parasitic infection of pet.Currently, the country is for pet The medication of helminth is infected there are slow effect, the problems such as anthelminthic effect is poor, and pharmaceutical preparation is complicated.
Summary of the invention
It is above-mentioned existing in the prior art it is an object of the present invention to solving for the deficiencies in the prior art One or more problems.For example, that one of the objects of the present invention is to provide a kind of anthelminthic effects is good, quick, preparation process is simple Single, pet composite tablet at low cost.
To achieve the goals above, an aspect of of the present present invention provides a kind of pet composite tablet, the composite tablet It can be made of following components in parts by mass: 18 parts~22 parts of Pyrantel Pamoate, 8 parts~13 parts of praziquantel, beef 40 parts~50 parts of powder, 15 parts~25 parts of starch, 1 part~10 parts of starch slurry, 1 part~2 parts of dextrin, 0.5 part~1 part of magnesium stearate.
In an exemplary embodiment of pet composite tablet of the invention, the starch slurry can be mass fraction 6%~10% starch slurry.
In an exemplary embodiment of pet composite tablet of the invention, the composite tablet can be by pressing below Mass parts meter at being grouped as: 19 parts~20 parts of Pyrantel Pamoate, 9 parts~11 parts of praziquantel, powdered beef 40 parts~50 Part, 15 parts~25 parts of starch, 1 part~10 parts of starch slurry, 1 part~2 parts of dextrin, 0.5 part~1 part of magnesium stearate.
In an exemplary embodiment of pet composite tablet of the invention, the composite tablet can be by pressing below Mass parts meter at being grouped as: 20 parts of Pyrantel Pamoate, 10 parts of praziquantel, 40 parts~50 parts of powdered beef, 15 parts of starch~ 25 parts, 1 part~10 parts of starch slurry, 1 part~2 parts of dextrin, 0.5 part~1 part of magnesium stearate.
In an exemplary embodiment of pet composite tablet of the invention, the usage and dosage of the composite tablet can 0.5 gram~1.0 grams of pet dosage for thinking every 5 kilograms~10 kg body weight.
Another aspect provides a kind of pet composite tablet preparation method, the preparation method may include Following steps: in parts by mass, by 18 parts~22 parts of Pyrantel Pamoate, 8 parts~13 parts of praziquantel, 40 parts~50 The powdered beef of part, 15 parts~25 parts of starch mix, and obtain mixture;1 part~10 parts starch slurries, preparation are added in the mixture Obtain softwood;0.5 part~1 part of magnesium stearate and 1 part~2 parts dextrin is added in granulation, whole grain, mixes, and tabletting obtains compound Tablet.
In an exemplary embodiment of pet of the invention composite tablet preparation method, the starch slurry can be The starch slurry of mass fraction 6%~10%.
In the exemplary embodiment of pet of the invention composite tablet preparation method, the mixture that obtains Step may include in parts by mass, by 19 parts~20 parts of Pyrantel Pamoate, 9 parts~11 parts of praziquantel, 40 parts~ 50 parts of powdered beef, 15 parts~25 parts of starch are uniformly mixed so as to obtain mixture.
In the exemplary embodiment of pet of the invention composite tablet preparation method, the mixture that obtains Step may include in parts by mass, by 20 parts of Pyrantel Pamoate, 10 parts of praziquantel, 40 parts~50 parts of beef Powder, 15 parts~25 parts of starch are uniformly mixed so as to obtain mixture.
Compared with prior art, preparation method simple process and low cost of the invention, can be adapted for heavy industrialization Generation, the composite tablet smooth appearance being prepared are disintegrated rapidly after taking, and anthelminthic effect is good.
Detailed description of the invention
By the description carried out with reference to the accompanying drawing, above and other purpose of the invention and feature will become more clear Chu, in which:
Fig. 1 shows the pet composite tablet preparation method flow diagram of an illustrative embodiment of the invention.
Specific embodiment
Hereinafter, pet composite tablet according to the present invention will be described in detail in conjunction with attached drawing and exemplary embodiment And preparation method thereof.
Fig. 1 shows the pet composite tablet preparation method flow diagram of an illustrative embodiment of the invention.
An aspect of of the present present invention provides a kind of pet composite tablet, in an exemplary embodiment of the present invention, The composite tablet can be composed of the following components, according to the mass fraction, 18 parts~22 parts of Pyrantel Pamoate, praziquantel 8 Part~13 parts, 40 parts~50 parts of powdered beef, 15 parts~25 parts of starch, 1 part~10 parts of starch slurry, 1 part of dextrin~2 parts, stearic acid 0.5 part~1 part of magnesium.
In the present embodiment, the starch slurry can be the starch slurry of mass fraction 6%~10%.Further, described Starch slurry can be the starch slurry of mass fraction 10%.
In the present embodiment, further, the composite tablet can be made of following components in parts by mass: double hydroxyls 19 parts~20 parts of naphthoic acid Pyrantel, 9 parts~11 parts of praziquantel, 40 parts~50 parts of powdered beef, 15 parts~25 parts of starch, starch slurry 1 Part~10 parts, 1 part~2 parts of dextrin, 0.5 part~1 part of magnesium stearate.
In the present embodiment, further, the composite tablet can be made of following components in parts by mass: double hydroxyls 20 parts of naphthoic acid Pyrantel, 10 parts of praziquantel, 40 parts~50 parts of powdered beef, 15 parts~25 parts of starch, 1 part~10 parts of starch slurry, paste 1 part~2 parts, 0.5 part~1 part of magnesium stearate of essence.
In the present embodiment, the usage of the composite tablet can be doted on to be every 5 kilograms~10 kilograms to weight The composite tablet of the invention that 0.5 gram~1.0 grams of object dosage.Certainly, composite tablet of the invention can equally follow the doctor's advice and take.
Another aspect provides a kind of pet composite tablet preparation methods, in pet compound of the invention In one exemplary embodiment of method for preparing tablet thereof, as shown in Figure 1, the preparation method may include:
Step S01, in parts by mass, by 18 parts~22 parts of Pyrantel Pamoate, 8 parts~13 parts of praziquantel, 40 Part~50 parts of powdered beef, 15 parts~25 parts of starch uniformly mix, and mixture is prepared.
It in the present embodiment, further, in parts by mass, can be by 19 parts~20 parts of Pyrantel Pamoate, 9 parts ~11 parts of praziquantel, 40 parts~50 parts of powdered beef, 15 parts~25 parts of starch are uniformly mixed so as to obtain mixture.Further, In parts by mass, can by 20 parts of Pyrantel Pamoate, 10 parts of praziquantel, 40 parts~50 parts of powdered beef, 15 parts~ 25 parts of starch is uniformly mixed so as to obtain mixture.
Step S02 is added 1 part~10 parts of starch slurry, softwood is prepared.
In the present embodiment, 1 part~10 parts of starch slurry can be added in the mixture, softwood is prepared. Further, 2 parts~8 parts of starch slurry can be added in the mixture, softwood is prepared.The starch slurry can be with For the starch slurry of mass fraction 6%~10%.Further, the starch slurry can be the starch slurry of mass fraction 10%.
0.5 part~1 part of magnesium stearate and 1 part~2 parts dextrin is added in step S03, granulation, whole grain, mixes, and tabletting obtains To composite tablet.
In the present embodiment, marumerization can be used softwood is pelletized, obtains carrying out again after dry particl whole Grain.
In conclusion preparation method simple process of the invention, the composite tablet being prepared can be used in driving away pet Intracorporal roundworm (such as: Toxocara canis, Toxocara cati, weight loss method), hookworm (such as ancylostoma caninum, ancylostoma braziliense, Ancylostoma ceylonicum, narrow first curved mouth nematode), whipworm (such as: Trichuris vulpis), tapeworm (such as: band-like band tapeworm, Taenia Pisiformis, Continuous multiceps, Mesocestoides fluke, carefully digs echinococcus, dibothriocephalus latus, winding palace category tapeworm at diphlidium caninum), Fluke (Schistosoma japonicum, Schistosoma mansoni, clonorchis sinensis, Paragonismus westermani, paragonimus skriabini, Echinochasmus japonicus, TaiWan, China spine band fluke, distoma conjunctum, Opisthorchis felineus, Fasciola hepatica), nematode etc. has anthelminthic effect good, takes effect The advantages that fast.
Although those skilled in the art should be clear above by combining exemplary embodiment to describe the present invention Chu can carry out exemplary embodiment of the present invention each without departing from the spirit and scope defined by the claims Kind modifications and changes.

Claims (9)

1. a kind of pet composite tablet, which is characterized in that the composite tablet is made of following components in parts by mass: double 18 parts~22 parts of hydroxyl naphthoic acid Pyrantel, 8 parts~13 parts of praziquantel, 40 parts~50 parts of powdered beef, 15 parts~25 parts of starch, starch slurry 1 part~10 parts, 1 part~2 parts of dextrin, 0.5 part~1 part of magnesium stearate.
2. pet composite tablet according to claim 1, which is characterized in that the starch slurry be mass fraction 6%~ 10% starch slurry.
3. pet composite tablet according to claim 1, which is characterized in that the composite tablet by pressing mass parts below Meter at being grouped as: 19 parts~20 parts of Pyrantel Pamoate, 9 parts~11 parts of praziquantel, 40 parts~50 parts of powdered beef, starch 15 Part~25 parts, 1 part~10 parts of starch slurry, 1 part~2 parts of dextrin, 0.5 part~1 part of magnesium stearate.
4. pet composite tablet according to claim 1, which is characterized in that the composite tablet by pressing mass parts below Meter at being grouped as: 20 parts of Pyrantel Pamoate, 10 parts of praziquantel, 40 parts~50 parts of powdered beef, 15 parts~25 parts of starch, form sediment 1 part~10 parts of slurry, 1 part~2 parts of dextrin, 0.5 part~1 part of magnesium stearate.
5. pet composite tablet according to claim 1, which is characterized in that the usage and dosage of the composite tablet is every 0.5 gram~1.0 grams of the pet dosage of 5 kilograms~10 kg body weights.
6. a kind of pet composite tablet preparation method, which is characterized in that the preparation method comprises the following steps:
In parts by mass, by 18 parts~22 parts of Pyrantel Pamoate, 8 parts~13 parts of praziquantel, 40 parts~50 parts of ox Digested tankage, 15 parts~25 parts of starch mix, and obtain mixture;
1 part~10 parts starch slurries are added in the mixture, softwood is prepared;
0.5 part~1 part of magnesium stearate and 1 part~2 parts dextrin is added in granulation, whole grain, mixes, and tabletting obtains composite tablet.
7. pet according to claim 6 composite tablet preparation method, which is characterized in that the starch slurry is quality point The starch slurry of number 6%~10%.
8. pet according to claim 6 composite tablet preparation method, which is characterized in that the step for obtaining mixture Rapid includes in parts by mass, by 19 parts~20 parts of Pyrantel Pamoate, 9 parts~11 parts of praziquantel, 40 parts~50 parts Powdered beef, 15 parts~25 parts of starch are uniformly mixed so as to obtain mixture.
9. pet according to claim 6 composite tablet preparation method, which is characterized in that the step for obtaining mixture Rapid includes in parts by mass, by 20 parts of Pyrantel Pamoate, 10 parts of praziquantel, 40 parts~50 parts of powdered beef, 15 parts ~25 parts of starch is uniformly mixed so as to obtain mixture.
CN201910095782.4A 2019-01-31 2019-01-31 A kind of pet composite tablet and preparation method thereof Pending CN109846842A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1099973A (en) * 1993-09-08 1995-03-15 四川省医学科学院寄生虫病防治研究所 Compound vermifuge for animals
CN103083344A (en) * 2011-11-03 2013-05-08 青岛康地恩药业股份有限公司 Compound praziquantel parasite repellent tablet for pets and preparation method thereof
CN107519169A (en) * 2017-09-14 2017-12-29 中国疾病预防控制中心寄生虫病预防控制所 A kind of composition for driving away echinococcus for canid and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1099973A (en) * 1993-09-08 1995-03-15 四川省医学科学院寄生虫病防治研究所 Compound vermifuge for animals
CN103083344A (en) * 2011-11-03 2013-05-08 青岛康地恩药业股份有限公司 Compound praziquantel parasite repellent tablet for pets and preparation method thereof
CN107519169A (en) * 2017-09-14 2017-12-29 中国疾病预防控制中心寄生虫病预防控制所 A kind of composition for driving away echinococcus for canid and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘蜀宝主编: "《药剂学》", 31 July 2007, 河南科学技术出版社 *
管俊昌等主编: "《病原生物学与免疫学》", 31 January 2018, 中国科学技术大学出版社 *

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Application publication date: 20190607