CN1098081C - Compound urea drops for ear - Google Patents

Compound urea drops for ear Download PDF

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Publication number
CN1098081C
CN1098081C CN99114254A CN99114254A CN1098081C CN 1098081 C CN1098081 C CN 1098081C CN 99114254 A CN99114254 A CN 99114254A CN 99114254 A CN99114254 A CN 99114254A CN 1098081 C CN1098081 C CN 1098081C
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CN
China
Prior art keywords
distilled water
urea
ear
ears
drops
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN99114254A
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Chinese (zh)
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CN1247064A (en
Inventor
张文继
周晓云
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First Affiliated Hospital of Anhui Medical University
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First Affiliated Hospital of Anhui Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by First Affiliated Hospital of Anhui Medical University filed Critical First Affiliated Hospital of Anhui Medical University
Priority to CN99114254A priority Critical patent/CN1098081C/en
Publication of CN1247064A publication Critical patent/CN1247064A/en
Application granted granted Critical
Publication of CN1098081C publication Critical patent/CN1098081C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The present invention relates to compound urea drops for ears. A plurality of kinds of medicines are added to distilled water to be sufficiently stirred; after the medicines are dissolved, glycerol is added to the distilled water; and a sufficient amount of distilled water is added to prepare the medicine liquid. The compound urea drops for ears are characterized in that the medicines comprise boracic acid, urea and dexamethasone phosphate. The compound urea drops for ears have the functions for promoting the growth of the tympanic membrane, resisting inflammation and maintaining moisture. Moreover, the compound urea drops for ears have the advantages of simple preparation, low cost and convenient use.

Description

Compound urea drops for ear
Technical field:
The present invention relates to a kind of [, exactly is a kind of compound urea drops for ear that promotes the tympanum growth.
Background technology:
The dense property of chronicity otitis media is that very common frequently-occurring disease of hals,Nasen und Ohrenheilkunde and sickness rate are high.Long-term or intermittent flow is dense with in ear clinically, the perforation of ear drum, auditory dysesthesia are characteristics, therefore not only bring misery but also influence life, study and work to the patient, also can cause inside and outside complication of serious cranium and the life security that jeopardizes patient sometimes.Treating this disease at first is that its inflammation is disappeared fully, remakes the tympanum reparation, can cure otitis media.Tympanum is repaiied film and is mostly adopted surgical repair in hospital at present, though healing otitis media, surgical repair not only need the medical care expenses of both expensive, general expenses are 2500-3000 yuan at present, therefore the patient is difficult to bear, and the operation of being in hospital brings the painful study and work that influences to the patient.
Summary of the invention:
Technical problem to be solved by this invention provide a kind of have promote tympanum growth, anti-inflammation, moisture-keeping function, and modulation is simple, cheap, easy to use compound urea drops for ear.
The technical scheme that technical solution problem of the present invention is adopted is:
The present invention is that addend flavor medicine fully stirs in distilled water, makes its dissolving back add glycerol, adds the capacity distilled water again and promptly is modulated into medicinal liquid, it is characterized in that counting the flavor medicated bag and draws together: boric acid, urea element and dexamethasone phosphate, and concrete liquid formula is:
Boric acid 2-6%, urea plain 3-7%, dexamethasone phosphate 0.1-4%, glycerol 15-30%.
Compared with the prior art, profitable fruit of the present invention is embodied in and can cooperates the otitis media patient to implement " choosing perverse method tympanic membrane repairing " effectively, it is chosen to promote the tympanum growth after perverse effectively, anti-inflammation and preserving moisture, thereby the patient need be in hospital, less, cure otitis media under the few situation of change expense in misery.The present invention simultaneously modulates simply, and is cheap, easy to use.
Clinical use is cured 478 ears perforation tympanum.Choose for the first time perverse after, once drip compound urea drops for ear every night, observe after five days, 388 ear perforation rims promptly have red fibrous loop growth, matched group 20 ear drum membranes perforation is chosen and once drip 0.25% chlorine syphilis eye water every night after perverse for the first time, observes after five days, 2 ear perforation rims have a little red fibrous loop growth, and 18 ears do not have significant change.The former promotes the effect of tympanum growth apparently higher than the latter, and X 2 test is shown: X2=53.4 P<0.01.
The specific embodiment:
Embodiment 1:
Get 2g boric acid and put into 35-45 ℃ of distilled water, stirring makes it dissolve back adding 7g urea element, 0.1g dexamethasone phosphate fully, fully stirs, it is dissolved fully, add 15ml glycerol again, add the capacity distilled water, making its total amount is 100ml, and adjusting PH is that 4-8 promptly gets required medicinal liquid.The patient uses, every day sooner or later each once, each 2, evident in efficacy.
Embodiment 2:
Get 6g boric acid and put into 35-45 ℃ of distilled water, stirring makes it dissolve back adding 3g urea element, 0.4g dexamethasone phosphate fully, fully stirs, it is dissolved fully, add 30ml glycerol again, add the capacity distilled water, making its total amount is 100ml, and adjusting PH is that 4-8 promptly gets required medicinal liquid.The patient uses, every day sooner or later each once, each 2, evident in efficacy.
Embodiment 3:
Get 3g boric acid and put into 35-45 ℃ of distilled water, stirring makes it dissolve back adding 6g urea element, 0.3g dexamethasone phosphate fully, fully stirs, it is dissolved fully, add 25ml glycerol again, add the capacity distilled water, making its total amount is 100ml, and adjusting PH is that 4-8 promptly gets required medicinal liquid.The patient uses, every day sooner or later each once, each 2, evident in efficacy.
Embodiment 4:
Get 4g boric acid and put into 35-45 ℃ of distilled water, stirring makes it dissolve back adding 5g urea element, 0.2g dexamethasone phosphate fully, fully stirs, it is dissolved fully, add 20ml glycerol again, add the capacity distilled water, making its total amount is 100ml, and adjusting PH is that 4-8 promptly gets required medicinal liquid.The patient uses, every day sooner or later each once, each 2, evident in efficacy.
Embodiment 5:
Get 5g boric acid and put into 35-45 ℃ of distilled water, stirring makes it dissolve back adding 4g urea element, 0.1g dexamethasone phosphate fully, fully stirs, it is dissolved fully, add 25ml glycerol again, add the capacity distilled water, making its total amount is 100ml, and adjusting PH is that 4-8 promptly gets required medicinal liquid.The patient uses, every day sooner or later each once, each 2, evident in efficacy.

Claims (1)

1, a kind of compound urea drops for ear, in distilled water, add number flavor medicine and fully stir, make its dissolving back add glycerol, add the capacity distilled water again and promptly be modulated into medicinal liquid, it is characterized in that: number flavor medicated bag is drawn together: boric acid, urea element and dexamethasone phosphate, and concrete liquid formula is:
Boric acid 2-6%, urea plain 3-7%, dexamethasone phosphate 0.1-4%, glycerol 15-30%.
CN99114254A 1999-06-09 1999-06-09 Compound urea drops for ear Expired - Fee Related CN1098081C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN99114254A CN1098081C (en) 1999-06-09 1999-06-09 Compound urea drops for ear

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN99114254A CN1098081C (en) 1999-06-09 1999-06-09 Compound urea drops for ear

Publications (2)

Publication Number Publication Date
CN1247064A CN1247064A (en) 2000-03-15
CN1098081C true CN1098081C (en) 2003-01-08

Family

ID=5277360

Family Applications (1)

Application Number Title Priority Date Filing Date
CN99114254A Expired - Fee Related CN1098081C (en) 1999-06-09 1999-06-09 Compound urea drops for ear

Country Status (1)

Country Link
CN (1) CN1098081C (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1137917A (en) * 1996-03-29 1996-12-18 王继德 Compound jiabing ear drops and preparation method thereof
CN1174079A (en) * 1997-08-29 1998-02-25 李凯堂 Medicine for abstaining from drugs and its preparation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1137917A (en) * 1996-03-29 1996-12-18 王继德 Compound jiabing ear drops and preparation method thereof
CN1174079A (en) * 1997-08-29 1998-02-25 李凯堂 Medicine for abstaining from drugs and its preparation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
临床耳鼻咽喉笠1997,11(4) 1997.4.30 金康业等耳炎灵治疗化脓性中耳炎的疗效观察 *
药学实践杂志1997,15(4) 1998.3.31 曲俊兵等复方氯霉素滴耳液的研制和临床观察 *

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