CN109803704A - For providing the equipment of impact type ventilation therapy to patient airway - Google Patents
For providing the equipment of impact type ventilation therapy to patient airway Download PDFInfo
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- CN109803704A CN109803704A CN201780061035.8A CN201780061035A CN109803704A CN 109803704 A CN109803704 A CN 109803704A CN 201780061035 A CN201780061035 A CN 201780061035A CN 109803704 A CN109803704 A CN 109803704A
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- gas
- pressurization
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
- A61H23/006—Percussion or tapping massage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/20—Valves specially adapted to medical respiratory devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
- A61H23/02—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M16/0006—Accessories therefor, e.g. sensors, vibrators, negative pressure with means for creating vibrations in patients' airways
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
- A61M16/0816—Joints or connectors
- A61M16/0841—Joints or connectors for sampling
- A61M16/0858—Pressure sampling ports
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
- A61M16/122—Preparation of respiratory gases or vapours by mixing different gases with dilution
- A61M16/125—Diluting primary gas with ambient air
- A61M16/127—Diluting primary gas with ambient air by Venturi effect, i.e. entrainment mixers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H2205/00—Devices for specific parts of the body
- A61H2205/08—Trunk
- A61H2205/084—Chest
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
- A61M16/022—Control means therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
- A61M16/0808—Condensation traps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/105—Filters
- A61M16/106—Filters in a path
- A61M16/107—Filters in a path in the inspiratory path
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0208—Oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3368—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/42—Reducing noise
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/502—User interfaces, e.g. screens or keyboards
- A61M2205/505—Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Rehabilitation Therapy (AREA)
- Percussion Or Vibration Massage (AREA)
Abstract
The present invention relates to for providing the method and apparatus of impact type ventilation therapy to patient airway, at least one actuator unit is preferably included, is configured to provide gas pressurize, non-fluctuating.At least one patient interface device preferably has structure, the structure is configured to: (i) receives pressurization, non-fluctuating gas from least one actuator unit, and convert thereof into pulsation and pressurization gas, and (ii) by patient connect aperture to patient supply at least one low tidal volumes pulsation and pressurization gas.At least one flexible pipe is preferably configured to provide pressurization, non-fluctuating gas from least one actuator unit at least one patient interface device.Preferably, at least part of patient interface device is disposable, and another part can be it is reusable.Preferably, the present invention uses adaptive dynamic low tide gas ventilating technology.
Description
The U.S. Provisional Patent Application No. US62/369 submitted this application claims on August 2nd, 2016,954 priority should
The full content of patent application is incorporated herein by reference.
Background technique
Respiratory tract is beaten with the wave of coordination by guiding lung mucus using the small hair of referred to as motile cilium
Promote to remove lung mucus to throat rear portion.The disease of such as chronic obstructive pulmonary disease (COPD) shows respiratory tract surface damage,
Inflammation (influencing the ability that cilium moves secretion) is caused, the logical of mucus generation and swelling limitation air-flow is increased
Road further reduced the ability of the discharge mucus of body.
With aging of population, the illness rate of tuberculosis is increasing, country especially high in smoking rate.
Acute and chronic tuberculosis management is still the important health problem with the significant death rate and disease incidence.In addition to inhaling
The other factors such as cigarette, infection and pollution, the density of population and urbanization, immigrant and whole world travelling all may cause tuberculosis prevalence rate
Increase.
The ventilator for providing the pulsation of small-pulse effect high frequency air is increasingly regarded as that alveolar is promoted to raise (therefore Pulmonary volume)
And facilitate effective treatment method that mucus secretion is removed from lung.Air impulsive motion provides dynamic for the air column in patient airway
Can, without triggering He-cloth Er Shi (Hering-Breuer) lung extension reflex, and provide mean airway positive pressure (PAP) effect
It answers.Mean airway positive pressure and oscillation air column help to move mucus, especially when being used in combination with pharmaceutical aerosol, although
Unclear exact operation mechanism.
Unfortunately, almost without the efficient apparatus for being capable of providing impact type ventilation therapy, and those are proved to effective
Device be expensive.
U.S. Patent number US4,592,349 disclose a kind of distal side (to patient) actuator unit comprising decompression is adjusted
Device and pneumatic oscillatory air interruption valve, to supply air impulsive motion to nearside patient interface device by hose comprising sliding text
Qiu Li mechanism, to provide the impact effect of enhancing.However, actuator unit uses pneumatic air interruption valve, need high pressure (high
High-frequency percussion effect could be reliably provided up to 40psi), leads to the noisy actuator unit of large size that power efficiency is low, it is necessary to by
Main power source operation, and manufacturing cost is very high.
U.S. Patent number US7,191,780 discloses a kind of for setting to the low cost of patient's conveying high frequency air pulsation
It is standby.This includes distal side actuator unit, which includes the pressure reducing regulator for constant compression air-source, with
And constructable flow disruption valve, air impulsive motion is supplied to nearside patient interface device by hose.
U.S. Patent number US8,365,727 disclose a kind of distal base unit comprising at least one electrical air
Disconnected valve, the electrical air interruption valve can from actuator unit compressed air source and pressure reducing regulator supply, or can be with
From the regulated pressure source supply for example from hospital air delivery outlet.Then, actuator unit outlet passes through hose to nearside
Patient interface device provides air impulsive motion.
However, (it uses air interruption valve by air arteries and veins to any method for generating impact type ventilation in the driver of distal side
It is dynamic to be transported to nearside patient interface device) it will be by due to including in the hose from distal side actuator unit to patient interface device
Air compressibility and inertia caused by shock effect reduction, and be subjected to the vein compliance due to hose itself and produce
Raw damping.In addition, air interruption valve must bear millions of secondary operation circulations during the actuator unit service life, it is easy
It wears and needs expensive maintenance to replace.
U.S. Patent number US4,592,349 in addition disclose how by using pneumatic servo assist sliding venturi shuttle with
Enhancing is applied to the surge pulsating waveform of patient, to enhance damping surging.However, such as pneumatic air interruption valve
Situation, it is also desirable to the high operating pressure (up to 40psi has relevant large volume, noise and poor efficiency) in actuator unit,
And the injection pressure for being applied to venturi inlet is usually less than 10psi.In addition, sliding venturi shuttle is only opened in one direction
It is dynamic, and double acting sliding venturi shuttle will improve the acutance for being applied to the pressure waveform of patient's lung airway, and therefore improve impact
Effect.
In consideration of it, a kind of low cost, low-power, low noise, effective impact treatment system are needed, the trouble with low cost
Person's interface arrangement operates together.
Summary of the invention
The present invention provides effective system and method, for promoting the mobilization of mucus using impact ventilation, reduces multiple
Therefore polygamy simultaneously reduces costs.It includes the pressurized-gas source from actuator unit, and the pressurized-gas source is with constant pressure
It is supplied to patient interface device.Patient interface device preferably includes single use portion and reusable part: repeatable to make
With air interruption valve is partially preferably used, and single use portion preferably uses venturi system.
The present invention also provides use adaptive dynamic low tide gas (Subtidal) ventilation (adaptive dynamic low tide gas ventilation skill
Art, referring to following definition) protect the effective system and method for injured lung.It is preferably included from actuator unit
Pressurized-gas source, the pressurized-gas source are supplied to patient interface device with constant pressure.Patient interface device preferably includes one
Secondary property part and reusable part: reusable part preferably uses gas halts valve, and single use portion is excellent
Selection of land is using sliding venturi system.
The purpose of the present invention is being preferably provided with effect, continuous, high-frequency impact type respiratory therapy, do not depend on
In expensive consumables.Another object of the present invention is preferably to reduce volume, noise and the complexity of actuator unit, with
Reduce manufacturing cost.A further object of the present invention is preferably to reduce the power consumption of system, to allow convenient transport and battery
Powered operation.Another object of the present invention is preferably to reduce maintenance and cost of serving.Another object of the present invention is excellent
Selection of land provides simple, convenient and wieldy system.
Another object of the present invention be preferably provided with effect, the ventilation of continuous, adaptive dynamic low tide gas is controlled
It treats.Another object of the present invention is preferably to reduce volume, noise and the power consumption for reducing system, with allow convenient transport and
Battery-powered operation.Another object of the present invention is preferably to reduce maintenance and cost of serving.Another object of the present invention
It is that simple, convenient and wieldy system is preferably provided.
According to the first aspect of the invention, the equipment for impinging air pulsation to be transported to patient preferably has at least
One actuator unit, the actuator unit are configured to provide gas pressurize, non-fluctuating.At least one patient interface dress
Setting preferably has structure, which is configured to: (i) receives pressurization, non-fluctuating gas from actuator unit, and by its
It is converted into pulsation and pressurization gas, and (ii) connects aperture by patient and supply at least one low tidal volumes to patient
The pulsation of (sub tidal volume) and pressurization gas.At least one flexible pipe is preferably configured to drive from least one
Dynamic device unit provides pressurization, non-fluctuating gas at least one patient interface device.Preferably, at least one described flexibility
The length of pipe is 1-7 feet.
According to the second aspect of the invention, the patient that impinging air is pulsed is conveyed to patient for connecting aperture by patient
Interface arrangement preferably has at least one gas access, which is configured to receive gas pressurize, non-fluctuating.Extremely
A few gas halts valve is preferably configured to receive pressurization, non-fluctuating gas from actuator unit, and converts thereof into
Pulsation and pressurization gas.At least one venturi valve is preferably configured to: (i) connects from least one described gas halts valve
Pulsation and pressurization gas stream is received, pulsation and pressurization gas is converted into the pulsation of at least one low tidal volumes by (ii)
And pressurization gas, and (iii) by the pulsation of at least one low tidal volumes and pressurization gas be transported to patient connect
Connect aperture.
According to the third aspect of the invention we, the actuator unit for impact type patient treatment preferably has at least one
Gas access, the gas access are configured to provide at least one pressurization, non-fluctuating gas at least one pressure vessel.Institute
It states at least one pressure vessel and is preferably configured to store at least one pressurization, non-fluctuating gas.At least one gas
Body outlet is preferably configured to export at least one pressurization stored, non-fluctuating gas from actuator unit.At least one
Electronic controller is preferably configured to: (i) receives signal from least one patient interface device, and described in (ii) control at least
The operation of one pressure vessel.
According to the fourth aspect of the invention, the equipment ventilated using adaptive dynamic low tide gas ventilating technology to patient
Preferably there is at least one actuator unit, which is configured to provide gas pressurize, non-fluctuating.At least
One patient interface device preferably has structure, which is configured to: (i) receives pressurization, non-arteries and veins from actuator unit
Dynamic gas, and pulsation and pressurization gas is converted thereof into, and (ii) connects aperture by patient and be supplied to patient
The pulsation of few low tidal volumes and pressurization gas.At least one flexible pipe is preferably configured to from least one driver
Unit provides pressurization, non-fluctuating gas at least one patient interface device.Preferably, at least one flexible pipe
Length is 1-7 feet.
According to the fifth aspect of the invention, connecting aperture by patient using adaptive dynamic low tide gas ventilating technology makes to suffer from
The patient interface device of person's ventilation preferably has at least one gas access, which is configured to receive pressurizeing, non-
The gas of pulsation.At least one gas halts valve is preferably configured to receive pressurization, non-fluctuating gas from actuator unit,
And convert thereof into pulsation and pressurization gas.At least one sliding venturi valve be preferably configured to: (i) from it is described at least
One gas halts valve receives pulsation and pressurization air-flow, and it is low that pulsation and pressurization gas is converted at least one by (ii)
The pulsation of tidal volume and pressurization gas, (iii) are defeated by the pulsation of at least one low tidal volumes and pressurization gas
Be sent to patient and connect aperture, and (iv) as air-breathing, outlet valve integrally operation, which means that the conveying of every Lower Low Water gas will be with
With the expiration of a low tidal volumes.
According to the sixth aspect of the invention, the driver of patient's treatment is carried out using adaptive dynamic low tide gas ventilating technology
Unit preferably has at least one gas access, which is configured to provide at least one pressure vessel at least one
Pressurization, non-fluctuating gas.At least one described pressure vessel is preferably configured to store at least one pressurization, non-
The gas of pulsation.At least one gas vent be preferably configured to from actuator unit export storage at least one pressurization,
Non-fluctuating gas.At least one electronic controller is preferably configured to: (i) is received from least one patient interface device to be believed
Number, and the operation of (ii) control at least one pressure vessel.
Detailed description of the invention
The exemplary embodiment of presently preferred features of the present invention is described with reference to the drawings.
Fig. 1 is residential care according to the present invention/treatment embodiment schematic block diagram, it is characterised in that actuator unit
Wireless connection between patient interface device.
Fig. 2 is residential care according to the present invention/treatment embodiment schematic block diagram, it is characterised in that actuator unit
Wired connection between patient interface device.
Fig. 3 is that hospital according to the present invention continuously ventilates the schematic block diagram of embodiment, it is characterised in that actuator unit
Wireless connection between patient interface device.
Fig. 4 is the schematic block diagram according to the embodiment of the actuator unit of Fig. 1 embodiment.
Fig. 5 is the schematic block diagram according to the embodiment of the actuator unit of Fig. 3 embodiment.
Fig. 6 is the patient interface device connector for being used to be attached to patient interface device according to the embodiment of Fig. 1-3
Perspective schematic view.
Fig. 7 a, 7b, 7c and 7d are the patient interface dresses for being attached to patient interface device according to the embodiment of Fig. 1-3
Set the perspective schematic view of connector;Wherein Fig. 7 a is rear perspective view, and Fig. 7 b is front perspective view, and Fig. 7 c is front plan view, figure
7d is side plan view.
Fig. 8 is the schematic block diagram according to the embodiment of the patient interface device of Fig. 1-3 embodiment.
Fig. 9 a is the perspective schematic view of the embodiment of patient interface device according to the present invention;Fig. 9 b is according to the present invention
Patient interface unit another embodiment perspective schematic view.
Figure 10 a is the schematic cross sectional views of the embodiment of patient interface device according to the present invention;Figure 10 b is according to this hair
The schematic cross sectional views of another embodiment of bright patient interface unit.
Figure 11 a is the schematic cross sectional views of the embodiment of patient interface device according to the present invention;Figure 11 b is according to this hair
The schematic cross sectional views of another embodiment of bright patient interface unit.
Figure 12 a is the schematic cross sectional views of the embodiment of patient interface device according to the present invention.Figure 12 b is according to this hair
The schematic cross sectional views of another embodiment of bright patient interface unit.
Figure 13 a is the schematic cross sectional views of the embodiment of patient interface unit according to the present invention;Figure 13 b is according to this hair
The schematic cross sectional views of another embodiment of bright patient interface unit.
Figure 14 a is the schematic cross sectional views of the embodiment of patient interface device according to the present invention;Figure 14 b is according to this hair
The schematic cross sectional views of another embodiment of bright patient interface unit.
Figure 15 a is the schematic cross sectional views of the embodiment of patient interface device according to the present invention;Figure 15 b is according to this hair
The schematic cross sectional views of another embodiment of bright patient interface unit.
Figure 16 a is the schematic cross sectional views of the embodiment of patient interface device according to the present invention;Figure 16 b is according to this hair
The schematic cross sectional views of another embodiment of bright patient interface unit.
Figure 17 a is the schematic cross sectional views of the embodiment of patient interface device according to the present invention;Figure 17 b is according to this hair
The schematic cross sectional views of another embodiment of bright patient interface unit.
Figure 18 a is the schematic cross sectional views of the embodiment of patient interface device according to the present invention;Figure 18 b is according to this hair
The schematic cross sectional views of another embodiment of bright patient interface unit.
Figure 19 a is the schematic cross sectional views of another embodiment of patient interface device according to the present invention;Figure 19 b is basis
The schematic cross sectional views of another embodiment of patient interface unit of the invention.
Figure 20 a is the schematic diagram of gas-entrained Venturi tube structure.Figure 20 b is the schematic diagram of Venturi tube structure.
Figure 21 a is the schematic cross sectional views of another embodiment of patient interface device according to the present invention;Figure 21 b is basis
The schematic cross sectional views of another embodiment of patient interface unit of the invention.
Figure 22 a is the schematic cross sectional views of another embodiment of patient interface device according to the present invention;Figure 22 b is basis
The schematic cross sectional views of another embodiment of patient interface unit of the invention.
Figure 23 a is the schematic cross sectional views of another embodiment of patient interface device according to the present invention;Figure 23 b is basis
The schematic cross sectional views of another embodiment of patient interface unit of the invention.
Figure 24 a is the schematic cross sectional views of another embodiment of patient interface device according to the present invention;Figure 24 b is basis
The schematic cross sectional views of another embodiment of patient interface unit of the invention.
Specific embodiment
Currently preferred exemplary embodiment
General introduction is got up, and the embodiment of the present invention provides family therapy and/or hospitalize device and method, thus at least one
The air flue of a patient provides impact type ventilation therapy.Although preferred embodiment can also the present invention is especially suitable for human patients
For any animal patient.
" adaptive dynamic low tide gas ventilation " (ADSV) technology in this specification may include but be not limited to structure and/or function
One or more of can or any combination thereof, thus patient interface device is: adaptability, because the stream of conveying will be fitted permanently
Answer the physiological parameter of patient;Dynamically, because it has a waveform, energy is brought to recruit air flue and influence Hemodynamics
(flow/pressure/volume permanent change is dynamic);Low tide gas, because it can convey the small size of referred to as low tidal volumes;
And ventilation, because it will affect gas exchanges, oxygen-containing and ventilation.
" controller " in this specification can include but is not limited to run " computer program " of one or more storages
Processing unit and/or for making device and/or unit execute non-transitory " computer-readable Jie of function as described herein
One or more of matter " or any combination.Medium may include compact disk, DVD, ROM, RAM, solid-state memory or can deposit
Store up any other storage device of one or more computer programs.
Term " processor " used herein indicates processing equipment, device, program, circuit, component, system and subsystem,
It is either realized with hardware, the software of tangible realization or the two, and regardless of whether programmable.Term " place used herein
Manage device " include but is not limited to one or more computers, hard-wired circuit, modification of signal device and system, be used for control system
Device and machine, central processing unit, programmable device and system, scene-programmable gate array, specific integrated circuit, piece
Upper system, the system being made of discrete component and/or circuit, state machine, virtual machine, data processor, treatment facility and appoint
What combination above-mentioned.
Term " storage " used herein and " data storage " and " memory " indicate one or more data storage devices,
Device, program, circuit, component, system, subsystem, position and storage medium, for temporarily or permanently retaining data, and
Such reservation data are provided.Term " storage " used herein and " data storage " and " memory " include but is not limited to hard disk,
Solid state drive, flash memory, DRAM, RAM, ROM, cassette and any other medium that mechanized data can be stored.
Fig. 1 and 2 depicts residential care according to the present invention/treatment embodiment.In Fig. 1, driver/source unit 10 is excellent
Selection of land is connected to patient interface device 16 by tracheae 12 and controller 14.Preferably, tracheae 12 preferably includes about 120cm
The Low compliance single-chamber plastic tube of (about 48 inches or 4 feet).Certainly, the length of pipe 12 can be any convenience or desired length
Degree, such as 2,3,4,5,6,7,8,9,10,11,12 feet or above-mentioned any feet, such as 1-7 feet, 2-6 feet, 3-5
Foot is bigger;As common vacuum hose, pipe 12 is also possible to stretchable.In this embodiment, actuator unit
10 preferably have low-power wireless interface 101, are connected to controller 14 via another low-power wireless interface 141.When
So, the power level of these interfaces can be adjusted according to local electric circumstance.In Fig. 2, actuator unit has wireline interface
102, the interface 142 of controller 14 is connected to via wiring 18.
Fig. 3 depicts hospital according to the present invention and continuously ventilates embodiment.In Fig. 3, controller 14, which can be set, to be driven
Dynamic device 10 nearby (or even in driver 10), and is preferably provided in hospital's shell 32, rather than as in Fig. 1 and 2
Patient interface device neighbouring like that.
Actuator unit.
Fig. 4 shows the main component of the actuator unit 10 according to Fig. 1 (family therapy) embodiment, is preferably included in
In plastics or metal shell 400.Power supply unit (PSU)/battery 402 supplies under the control of electronic controller 404 to various parts
Electricity.Liquid crystal display (LCD)/touch screen unit 406 can be used for programming and operating controller 404, and/or monitoring connects from patient
The feedback of mouth device 16, as will be described in more detail.When may need input and/or feed back when, buzzer (or it is other can
Listen and/or visual alert label) 405 preferably to nursing staff provide feedback.Electronic controller 404 passes through 481 control of wiring
One or more preferred brushless direct-current (DC) motors 408.D.c. motor 408 preferably drives scroll compressor 410, will
Non-pulsating air is supplied to the gas access 411 of pressure vessel 412.Surrounding air is via air filter 414 and admission line
416 are supplied to scroll compressor 410.
Pressure vessel 412 preferably includes pressurized tank and connector appropriate.Preferably, pressure vessel 412 had
Safety valve 418 is pressed, to allow air to escape from the pressure vessel 412 of over-voltage.Preferably, safety valve 418 further includes that pressure passes
Sensor 419 sends controller 404 for over-voltage signal by wiring 420.Then, controller 404 can order d.c. motor
408 stop pressurizeing to pressure vessel 412.Pressure vessel 412 preferably has operating pressure sensor 422, detects pressure
Pressure in container 412 simultaneously provides pressure signal to controller via wiring 424.Water collector 426 is preferably coupled to pressure appearance
Device 412, and provided by fluid line 428, fluid connection 428 and Patient interface connector 470 to patient interface device 16
Fluid is described in more detail below.Electric wire 432 preferably will be automatically controlled via electrical connector 434 and Patient interface connector 470
Device 404 processed is connected to patient interface device.Certainly, the connection between actuator unit 10 and patient interface device 16 can be
Line, wireless or both combination.
In use, actuator unit 10 is preferably provided to a few non-pulsating compressed gas source, and using programmable
Electronic controller 404 and touch-screen display 406 are to construct impact session.For example, 404 He of controller can be used in nursing staff
Touch-screen display 406 is supplied to one or more session frequency of impacts of patient interface device 16, such as 100-200 to be arranged
Or 100-400 cycle per minute clock and operating pressure, such as 20-30 or 20-40psi.Controller 404, which can also monitor, to be delivered
It treats and (comes from patient interface device 16) to provide feedback, such as duration for the treatment of, such as 15-30 minutes to nursing staff,
Or 15-60 minutes, patient-proximate's pressure, such as 5-10 or 5-20cmH2O etc..Controller 404 can also be provided to attendant
Information, such as hour use, fault state etc..Touch-screen display 406 is provided to system parameter, monitoring data and any failure
The simple and quick access of situation, and it is best to guide nursing staff to carry out by setting system to be also integrated with built-in agreement
Treatment.
In use, actuator unit 10 preferably provides non-pulsating compressed air source to patient interface device 16.To trouble
The air pressure of such as 10psi of person's interface arrangement is preferably adjusted by electronic controller 404, which is compressor
410 provide power.Electronic controller 404 preferably with 4.3 inches of graphic lcd interfaces with integrated touch screen 406
Connection, to allow nursing staff to configure treatment parameter.Electronic controller 404, which preferably handles to come from, is embedded in patient interface dress
The signal of sensor in setting and (will be described below), and those feedback signals are shown on display 406.Electronic controller
404 preferably also monitor the health status of whole system and the use of nursing staff and/or attendant, and further preferably
The session information of the doctor of ground storage record is to monitor therapeutic advance.For example, can use the setting of controller 404, adjusting, control
Pressure, frequency, time, air-breathing/expiration ratio, vital capacity determination, the alarms such as system, storage etc..
It is preferred in use, actuator unit 10 using the typical 24V@1/4HP brushless motor 408 of small low-voltage come
Drive the oil-free scroll formula compressor 410 powered by electronic controller 404.The preferably cleaning ambient of replaceable filter 414 is empty
Gas is to be supplied to air compressor 410.Compressor 410 preferably fluid supply small, light pressure vessel 412 (its can be or
Composite construction light alloy suitable for low operating pressure (such as 20psi)), then the pressure vessel passes through check valve 429, catchments
Device 426 and connection hose 428 supply patient interface device 16.Pressure in pressure vessel 412 is preferably passed by semiconductor pressure
Sensor 422 monitors, which is supplied to electronic controller 404 for pressure reference signal.Electronic controller 404
Continuously change the energy for arriving direct current (DC) compressor 410, to provide enough air pressures and flow to patient interface device 16,
Energy consumption is reduced to minimum simultaneously, and therefore reduces noise.Pressure vessel (reservoir) 412 is preferably also comprised for pacifying
Full overpressure safety valve 418, it is therefore preferred to have to the appropriate electrical contact feedback system 419 of controller 404, preferably to user
Indicate any fault state.
In use, electronic controller 404 preferably includes memory 405, and agreement setting library is retained in the memory.
This will make nursing staff be easier to be arranged.For example, predefining the pre-programmed setting side for having neuromuscular patient in controller 404
Case is atomized for example, providing 2 minutes, impact in 10 minutes is then carried out at 8Hz, then carries out 5 minutes at 1 hz, and use
Treatment is completed in atomization in 1 minute.
Same in use, actuator unit 10, which preferably includes, is provided by electronic controller 404 and is stored in electronics control
Various alarms and cautionary characteristic in device 404 processed.Nearside patient's high pressure alarm is preferably preset as 60cmH2O, but can mention
For other and/or extra level.If detecting that proximal pressure is more than at patient-proximate's pressure sensor (being described below)
One or more pre-set pressure limits, then electronic controller 404 is preferably programmed to operate police for example at buzzer 405
Report: alarm will sound, and then impact treatment will stop, and show error message on graphic lcd 406.Nearside patient
Low pressure warning can also be preset as such as 5cmH2O, but other and/or additional levels can be used.If in patient pressure
The pressure lower than preset pressure is detected at sensor, then controller 404 is preferably programmed to operation audible alert 405 and shows
Show message.Preferably, display 406 will indicate that nursing staff checks that venturi flow valve and patient interface breathing circuit (will be
Be described below) in leakage, and restart session.In initial system setting, nursing staff can configure expiration feedback letter
Number.Preferably, in the optimum working pressure for determining such as 20psi, (based on patient chest swing, (which reflects intrathoracic punchings
Hit/energy wave transmission validity) and patient comfort (which reflects patients easily to breathe during treatment, inhales
The easy degree of gas and expiration)) after, other than patient-proximate's pressure (for example, 15cmH2O), nursing staff will usually be exhaled
Gas feedback signal is set as such as 10cmH2O, more than the proximal pressure amplitude of measurement.Expiration feedback signal, which preferably includes, to be passed through
The audible buzzer of buzzer 405 helps training patient to pass through the venturi stream in patient interface device during treatment
Amount valve cosily breathes, and introduction patient avoids excessively exhaling.Progressive and stable expiration reduces lung volume, keeps treatment more effective
And a possibility that overwhelming patient is reduced, especially when being in a bad way.In fact, expiration feedback signal is educational, introduction
How patient effectively breathes during treatment, and usually 15 to 30 minutes.By using menu touch screen control, used by figure
Expiration feedback signal is arranged to execute in the expiration alarm setting display screen that family interface (GUI) navigates on display 406.
In order to carry out treatment can except home environment, the power supply of system preferably includes medical grade efficient switch mould
Formula main power source (will be described below), and this is to be preferably adapted to be switched for replaceable battery group 402.In order to mitigate
Weight simultaneously improves portability, and battery pack 402 generally includes lithium ion battery, or in transportation safety (such as commercial airline companies)
It can be such as nickel metal hydride in the case where more concerned.Another power supply device still used convenient for open air, drives
Dynamic device unit includes the non-removable efficient medical grade main power source of integral type, and preferably has automobile accessory power supply
Line obtains 12V power supply in automobile or trailer.
Fig. 5 is the schematic block diagram according to the embodiment of the actuator unit 10 of Implementing Hospital example.Hospital is existed by setting
Hospital air/oxygen (O2) entrance 502 in the wall of shell 500 provides forced air supply.The air/oxygen of supply is via pipe
Line/pipeline 504 is transmitted to inlet filter 506, and is transmitted to inlet pressure transducer 506 via pipeline/pipeline 508.According to
The air/oxygen for supplying how many stress level to one or more patients by Patient interface connector 470, forced air is supplied
One or more pressure vessels 512 should be arrived to 51N.Preferably, forced air passes through 520,522,524 and 520N of pipeline/pipeline
Transmission.Before injecting above-mentioned pressure vessel, this forced air preferably passes through one or more corresponding pressure reducing regulators
532,534 and 530N (being controlled by corresponding 542,534 and 530N of servo motor).Preferably, each pressure vessel 512 is to 51N
With excess pressure valve 5121,51N1 and sensor 5122,51N2, as described above.Moreover, each pressure vessel preferably has work
Pressure sensor 5133,51N3 provide output signal to controller 404, as described above.Similarly, each pressure vessel has
It is connected respectively to water collector 5144,5145,51N4 of 5154,5155 and 51N5 of fluid connector, the installation of these fluid connectors
In Patient interface connector 470, also as described above.
In use, system can operate continuously in a standalone mode, or operate together with other third party's ventilator,
The patient that oneself cannot be breathed for those.When operating in the independent mode, actuator unit 10 is also designed to trouble
Person is failure safe.Different from residential care device, in Implementing Hospital example, actuator unit 10, which is preferably provided with, to be come from
High pressure (usually 75psi) compressed gas (air and/or oxygen) source of hospital outlet, and can have to patient interface device
16 multiple hoses.Patient interface device 16 provides additional function, such as more multisensor preferably to monitor treatment, Yi Jijia
Heat is to provide warm air to patient.
With reference to Fig. 5, in use, actuator unit 10 preferably includes the appropriate medical level power supply suitable for cardiac environment
402.The gas line of actuator unit 10 preferably include the water collector 5144 preferably near each pressure vessel outlet,
5145,51N4, and can also be comprising heating element to preheat the gas for being transported to patient interface device 16.Actuator unit
At least one non-pulsating compressed gas source is preferably supplied to patient interface device 16 by 10.According to clinical needs, gas supply
It can be clean air, oxygen or mixed with external oxygen/air mixer.Alternate embodiment can also include for independent
Oxygen mixer in the actuator unit 10 of system.Actuator unit 10 preferably include at least one pressure reducing regulator 532,
534,530N can be manually adjusted, or preferably by electronic controller 404 it is electronic and power supply.Basic hospital system is preferred
Ground uses single pressure reducing regulator 532, and more complicated system is soft using at least two pressure reducing regulators 532,53N and correlation
Pipe supplies patient interface device 16 --- and adjuster is to provide low pressure feed to patient interface device 16, another adjusting
Device provides the supply of higher pressure for entrainment.
In the embodiment using fail-safe system, each pressure reducing regulator is preferably the design of " failure is closed ",
The redundancy of multiple pressure reducing regulator forms, and patient safety will not be jeopardized in the failure of any one adjuster or processor
In the case of using multiple processors electronic controller 404 be used to ensure continue supply.Actuator unit 10 preferably includes use
In each pressure reducing valve pressure vessel for use as surge tank, because according to hospital infrastructure, it is known that nearby work its
Its device can have an impact pressure stability.Each pressure vessel is preferably used for safety and dependent failure detection contact
Overpressure safety valve, and be also the semiconductor pressure sensor for measuring available pressure.
Electronic controller 404 is preferably connect with liquid crystal picture display and 406 interface of touch screen, allows to construct and show
The operating pressure for treating parameter and every pipeline.Electronic controller 404 preferably monitors hospital by pressure sensor 506
Gas monitor inlet pressure, and preferably sounded an alarm when inlet pressure exceeds tolerance.Electronic controller 404 is also handled
Signal (will be described below) from the sensor being embedded in patient interface device 16 is simultaneously shown on display 406.Electricity
Sub-controller 404 preferably includes look-up table and/or control algolithm, such as proportional integration (PI is a kind of IC chip,
Allow controller that can be used as Closed loop operation, herein in this case, controller will be according to the nearside for being conveyed to patient
The variation adjusting work pressure of pressure), with according to the electronic pressure reducing regulator of feedback regulation of related pressure container pressure sensor,
To provide required operating pressure.Electronic controller 404 also monitors overall system health situation, for example, monitoring is for servicing people
The system and/or component of member, and the session information of storage record is for doctor monitoring patient progress.Electronic controller 404 is excellent
Selection of land includes interface 434 appropriate, such as Ethernet, is connected to hospital network using agreement appropriate (such as HL7), to permit
Perhaps patient parameter is remotely monitored by centralized observation station.
Connector
Fig. 6 is the patient interface device connector for being used to be attached to patient interface device 16 according to the embodiment of Fig. 1-3
470 perspective schematic view.In this embodiment, quickly disconnecting device 470 preferably has cylindrical metal or plastic housing
Body 610, with recessed internal platform 620, which is circular and is arranged in below connector antelabium 612
Depth is at least deep as the height of air cone 650 and/or electrical connection pin 660i to 660n.Air cone 650 supplies forced air
Patient interface device 16 should be arrived, and sells 660i to 660n and telecommunication is provided.Shell 610 be preferably incorporated in shell two sides or
L shape interlock slot 670 on more sides, is locked to the complementary locking structures on patient interface device 16 for connector 470.Pass through
One or more air hoses/680 pressurised air of pipe/pipeline.Preferably, electrical connection wiring 690i to 690n is around sky
The beam in sheath that gas pipeline 680 is wound, as shown in the figure.In this embodiment, connector 470 can be fixed to actuator unit
10 and patient interface device 16 can be removably coupled to.However, connector can be fixed to patient interface device 16 simultaneously
And actuator unit 10 can be removably coupled to.In another embodiment, have on each end of umbilical and connect
Device 470 is connect, umbilical is removably coupled/separated with both actuator unit 10 and patient interface device 16.
Fig. 7 a, 7b, 7c and 7d are the schematic perspectives according to the patient interface device connector 470 of the embodiment of Fig. 1-3
Figure.In these figures, linear (square and/or rectangle, or both combination) solid or hollow housing 710 its at least one
There is the antelabium 712 inwardly rotated on a edge, be constructed for attachment to patient interface device 16.It provides one or more
Through-hole 720 is to be fixed to patient interface device 16 for shell 710 by fixed device (such as screw, angle lever, lever etc.).For
Gas coning 751 and 752 is for supplying high pressure and low-pressure air and/or oxygen;More or fewer air cones can of course be provided.Electricity
Connector 660i to 660n is preferably on two rows of two sides that air cone complementally is arranged in.
In use, actuator unit 10 provides at least one continuous compressed air source to patient interface device 16, and
And also provide electrical connector.In order to avoid obscuring and incorrect connection, patient interface device air hose and connector assembly
Integrated connector is preferably used, wherein fluid pressure line is included in the umbilical with spiral winding electric wire.Connector
470 preferably include the air line tapered coupling of at least one center installation, and wherein electrical connector pin surrounds taper connection
Device radial direction (and/or linearly) be spaced apart, in shell and using the suitable ergonomics lock for being suitble to target user
Determine mechanism, such as a quarter turns lock collar, antelabium and screw etc..It, can be using double in the case where multiple air lines
Chamber fluid connector.Alternatively, patient interface device connector 470 may include linear shell 710, one
Side has tapered air pipe connector, and the other side has electricity pin or planar junction, and preferably in side using removable
It unloads hinge and locking key mechanism is turned using a quarter in the other side, as shown in Figure 7a.In addition, one or more insulation heating units
Part 681 can also exist on heated compression gas to the temperature delivered more suitable for treatment in air hose 680, and the temperature is excellent
Selection of land is monitored by least one temperature sensor 811 (Fig. 8) in patient interface device 16.
Patient interface device
Fig. 8 is the schematic block diagram according to the embodiment of the patient interface device 16 of Fig. 1-3 embodiment.Device 16 is preferably
Including shell 800, pressurized gas inlet pipe/pipeline/hose 810, temperature sensor 811, air interruption valve 820, venturi stream
Measure valve 850 and atomizer 860.Atomizer passes through one or more pipelines 862 by carrying port 864 secretly to air interruption valve 820
Supply drug appropriate.Pulsation and pressurization gas passes through one or more pipe/pipeline/hoses 822 from air interruption valve 820
It is supplied to venturi valve 850.One or more make-up gas (such as oxygen) can by pipeline/pipe/hose 824, by setting
The make-up gas port 826 set in the wall of shell 800 is supplied to pipeline 822.Venturi valve 850 can make exhaled gas by one
One or more expiration ports 854 in wall that a or multiple flexible hose/pipe/pipelines 852 pass through shell 800.Venturi valve
850 preferably pass through the one or more conveyings being arranged in the wall of shell 800 by one or more hose/tube/pipelines 860
One or more pulsation and pressurization gas is supplied to patient in port 862.Preferably, the sensor in venturi valve 850 (will
It is described below) signal is provided to electronic controller 404 by electric wire 870.
In more detail, patient interface device 16 preferably includes: venturi flow valve 850, is used as flow rate pressure and pressure
Power-flow converter;And air interruption valve, generation shock effect is brought to generate the pulse artery of air/gas.Atomizer
860 preferably application drugs are humidified to patient and/or by the breathing gas of patient.Preferably, venturi 850 is designed to provide pressure
Power-flow and flow rate pressure conversion, wherein first gas pulsation preferably generates maximum entrainment from air entrainment port 864, and
And the low tidal volumes for being transported to the gas of patient airway are larger.Then, gradually increasing for the pressure in patient airway will reflect in
In the delivery port 862 of venturi flow valve 850, and according to venturi theory, the intracorporal pressure of valve will increase, and become environment
Pressure, and reduce entrainment flow.Therefore, the low tidal volumes for being transported to patient airway become smaller and smaller and are finally reached balance.
This is referred to as the ventilation exchange of low tide gas;After this stage, each low tidal volumes conveying, a low tide will be breathed out from patients with respiratory tract
The gas of tolerance is simultaneously discharged by valve expiration port 854, all gas exchange will occur, patient will be oxygenated during the entire course for the treatment of
And ventilation.Exhaled gas from patient will leave valve by expiration port 854, which also may include adjustable stream
Dynamic resistance, to promote the stabilization of the upper respiratory tract, especially in the patient of pulmonary exacerbation.
Patient interface device 16 preferably includes air interruption valve 820, can take various forms, suitable for acting on
High frequency pressure pulsations are introduced and/or generated when from the forced air of actuator unit 10.Air interruption valve 820 preferably constructs
At in response to being repeatedly opened and closed inner openings from the signal of controller 404 by electric wire 821, in large-scale frequency
Pulsating pressure force flow is generated in rate and pressure (such as 1-15Hz).Further, it is also possible to which replenishing port 826 is arranged, it is used to receive benefit
It those of is oxygenated patient, is also entrained in port 827 in the mode similar with air entrainment port 864.These ports exist
It can cover when not in use.
With reference to Fig. 9 a and 9b, the patient interface device 16 for being intended to use in short term for family is shown.Preferably, the patient
Interface arrangement 16 is using completely short-term reusable component, because it reduce each use costs, and for example pass through
Certain elements that hand and/or dish-washing machine carry out clean device are acceptable.This reusable component may include sky
Gas interruption valve 820, venturi valve 850, atomizer 860 and/or one or more of various pipelines and port.These are usually
The Bullet structure that single patient uses, patient (usually several days) during short stay reuse, then abandon.
Other than user interface controls 907, patient interface device 16 can also be comprising auxiliary electronic controller 905 and small
Type liquid crystal display 906 carries out minor adjustments to treatment session to provide local visual feedback and also allow.Display and control
Device processed can be set be similar to current video camera system it is hinged turn over/under turn in structure.Air interruption valve 820 is excellent
Selection of land is mounted in the Mechatronic Systems in patient interface device 16.Preferred embodiment does not use needle-valve to provide pulsation to patient
Stream --- any valve for being responsible for conveying Pulsating Flow to patient preferably throws open and closes, and reaches maximum pressure wave, so as to most
Bigization impact effect.This can compress bullet by using the poppet (being described below) and buckling of one or more Electromagnetically-operatings
Spring (also described below) is realized preferably providing nonlinear spring pressure, or is realized by preloading poppet,
The preloading poppet is since the fine drilling in structure generates bias, fine to drill to allow valve moment to open and close
Gas will be allowed to escape, and depressurize the space around poppet, to reduce air drag when poppet is moved forward and backward.It is preferred that
Ground adjusts electronic valve frequency of impact (for example, 100- per minute by the electric signal from actuator unit electronic controller 404
900 circulations) and duty ratio (for example, 0-50 circulation per minute).
In use, air interruption valve 820 is preferably supplied ejection assemblies, which is directed to text for air impulsive motion
In mound in valve 850.This generates subatmospheric region before venturi system around ejection assemblies, which passes through sky
Gas entrainment port is opened to secondary chamber.Atomizer 860 is preferably connected to venturi valve, and mist via entrainment port 864
Change device 860 and preferably supplies venturi valve 850 due to the subatmospheric power in front of venturi and via entrainment port 864, into
One step generates the barometric gradient across atomizer.Atomizer 860 may also include secondary air inlet 869.Secondary inlet 869 is preferred
Ground is covered with one-way flapper valve 871, to limit the evolution of drug containing aerosol, and can be carried secretly by venturi valve 850 in addition to providing
Supplementary therapy air intake except, also reduce undesirable exposure to nursing staff.
One embodiment of atomizer 860 may include aerosol generator, accelerate defeated from bowl by capillarity
The drug containing liquid flow sent, the drug containing liquid flow is to leave at a high speed nozzle.Then injection stream hits spray lance, generate aerosol.Gas
Colloidal sol is inhaled into venturi valve 850 by carrying port 864 secretly.Atomizer 860 can be disposably.Preferred embodiment is using pressure
Electric ultrasonic atomizer 860 is further reduced compressed air consumption and therefore reduces driver because they do not need compressed air
Cell power consumption and noise.Ultrasonic atomizer 860 is intended to be reused and be designed to sterilize completely.In ultrasonic atomizer
It is supersonic generator in 860 comprising: there is the dome orifice plate in the hole being precisely formed, which controls the ruler of aerosol droplets
It is very little;And piezoelectric vibration device, micro- pump action is generated with atomization medicine.Gravity contacts drug with aerosol generator;
Then liquid is drawn through orifice plate and is converted into aerosol.It is connect at display control graphical user interface (GUI) 907 in nursing staff
When receiving corresponding selection, controller operates atomizer.
Venturi flow valve 850 preferably acts as flow rate pressure and pressure-flow converter.Venturi valve 850 is preferably
Aperture 950, expiration port 854 and spray nozzle assemblies are connected including venturi entrainment port 864, patient.Based on venturi original
Reason, the low tidal volumes variable according to the conveying of the air flue feature of patient of venturi valve 850, integrally serves as air-breathing/outlet valve, and
And generate the Positive Airway Pressure of substantially unitary level.
Figure 10 a to 12b shows the static venturi valve 850 with 1002 one of single use portion of patient interface device 16
Embodiment, wherein reusable part 1004 includes electromechanical and/or pneumatically-operated interruption valve.
Figure 10 a and 10b are shown to interrupt including the electromagnetic air of single use portion 1002 and reusable part 1004
System, wherein reusable part 1004 preferably includes solenoid 1010, wherein solenoid armature axis 1012 forms two
Poppet valve system 1020,1022.Single use portion 1002 preferably includes fixed venturi flow valve 850, and repeatable makes
It is preferably screwed in single use portion 1002 via screw thread 1030,1032 before the use with part 1004.Preferably, one mentions
Lift valve 1022 supplies a gas to venturi valve 850, and the second poppet 1020 is by one or more drilling pipes 1025 (Figure 10 a)
It is biased from gas supply device 860.When system is opened, then gas passes through poppet 1020 from 860 to 1025 and passes through two
A lateral narrow pipe drilling evolution.Figure 10 a shows the poppet of closing, and Figure 10 b shows open poppet.The right side of axis 1012
End is used as the poppet 1022 of venturi valve spraying system 850, and secondary biggish poppet 1020 also serves as pressure servo
Valve module is biased in open edge from the chamber adjacent with primary poppet 1022 by narrow drilling pipe by mechanism.Once
Solenoid 1010 is powered, and the power on secondary valve head and the secondary poppet 1020 of biasing quickly open two poppets together
1020,1022, to allow air to be transported to venturi valve 850 by ejection assemblies 860.Biasing gas in secondary poppet 1020
Body pressure is discharged after opening.Once solenoid 1010 powers off, reset spring 1013 is shut off two valves 1020,1022, and
Circulating repetition.Alternatively, voice coil systems can be used for providing valve shaft by replacing solenoid armature with permanent magnet
1012 double-direction control.Furthermore it is possible to occlusion expiratory air port 854 is completely or partially synchronized using secondary solenoid,
To maximize nearside patient expiration positive pressure (PEP) effect.One or more ports 1036,1038 provide entrance and are such as flowed with measuring
The parameter of amount, pressure, spirometer etc..
Figure 11 a and 11b show electromagnetic air and interrupt system comprising single use portion 1102 and reusable part
1104, wherein reusable part 1104 includes solenoid valve 1110 and buckling compressed spring 1113 to provide nonlinear spring
Power.Single use portion 1102 preferably includes fixed venturi valve 850, and reusable part 1104 is preferably using
It is screwed in single use portion by screw thread 1130,1132 before.
Preferably, reusable part 1104 starts poppet 1122 using solenoid 1110, and wherein poppet makes
Open edge is biased in nonlinear spring 1113.Figure 11 a shows the poppet 1122 of closing, and Figure 11 b, which is shown, to be beaten
The poppet 1122 opened --- it is to be noted that the band button spring 1113 of open position.The right end of solenoid armature axis 1112 is used as
The poppet 1122 of venturi valve spraying system 850, and the gas pressure on poppet biases buckling compressed spring 1113,
Therefore poppet 1122 is in the edge opened.Once solenoid 1110 is powered, valve 1122 is opened, then when solenoid 1110 is disconnected
It is closed when electric due to spring 1113.As shown in Figure 10 a and 10b above, alternative solution is with permanent magnet replacement solenoid electricity
Pivot is to allow the double-direction control of valve shaft 1112.It exhales furthermore it is possible to completely or partially synchronize occlusion using secondary solenoid
Air port 854, to maximize nearside patient expiration's positive pressure effect.
Figure 12 a and 12b show electromagnetic air and interrupt system comprising single use portion 1202 and reusable part
1204.Reusable part 1204 preferably includes pneumatically-operated double acting (double acting) shuttle valve 1260, and
Disposable 1202 part preferably includes fixed venturi valve 850.Reusable part 1204 preferably leads to before the use
Screw thread 1230,1232 is crossed to be tightened in single use portion 1202.
Figure 12 a shows the poppet 1222 of closing, and Figure 12 b shows open poppet 1222 --- pay attention to shuttle valve
1212 move from one side to the other.If desired, individual gas feedthroughs 1299 can be used for patient and supply and operate shuttle.
Pneumatic slide shuttle 1260 preferably includes air flue 1261,1262, the gas under pressure is directed to port 1271 in shell,
1272, in 1273,1274.Shuttle valve 1260 generally includes the metal or plastic material of hardening, and is integrated into patient interface device
In 16 reusable part 1204.Preferably, needle-valve 1277,1278 is used to measure the gas being discharged from every side of shuttle ---
Once the gas pressure in the side of shuttle is more than the other side, shuttle is just moved past.Double acting property is conducive to active air impeding shutdown
System 820, to sharpen the pressure fluctuation for being intended to enhance impact treatment effect.In a preferred embodiment, be adjusted needle-valve 1277,
1278 are preferably used motor/servo-system to control, and wherein actuator unit electronic controller 404 includes to be directed to required impact
The calibration table of the needle-valve setting of frequency.Once it is determined that best setting, such as duty ratio, simplify version can be omitted for one or
The needle-valve of multiple drilling pipes.
Figure 13 a and 13b show completely disposable patient interface device 16 comprising whole static venturi valve 850,
It has the pneumatic relay 1305 of integrated single-acting using sliding shuttle valve 1360.Figure 13 a shows in the closed position
Shuttle valve is slided, Figure 13 b shows sliding shuttle valve 1360 in an open position.Obviously, individual gas source can be used respectively
860,1380 to supply patient by venturi valve 850, and for operating shuttle valve 1360.Completely disposable patient interface shuttle valve
1360 use needle-valve 1370 preferably compressed gas to be metered into sliding shuttle valve.Shuttle valve 1360 is preferably by nonlinear buckling
Spring 1313 remains turned-off.When the pressure in 1360 chamber of shuttle valve is more than preset threshold, shuttle overcomes spring pressure, and valve
1360 is mobile to open gas passage 1375.This opens air flue and supplies a gas to text by the drilling 1361 in shuttle 1360
Valve 850 in mound.Second needle-valve 1371 forms chamber when shuttle moves past, and when exhaust, shuttle 1360 is in situ since spring force returns, and dashes forward
The gas so closed to venturi valve 850 is supplied.If necessary to simplified control, then the needle 1371 can be replaced with drilling.
It, can be using sliding venturi valve 850, to pass through when venturi reaches its limit of sports record in the case where needing additional impact
Pressure wave is generated to enhance impact effect.
In use, adjustable gauge needle combination venturi valve 850 controls frequency of impact and duty ratio.Needle-valve can be with hand
Dynamic operation, and electronic controller 404 simply counts operation at any time to obtain frequency of impact.In such case
Under, when sliding shuttle interruption valve can be made of plastics and be molded into patient interface device 16, patient interface device 16 can
To be completely disposable, because of the problem of this is eliminated due to shuttle surface abrasion over time.Figure 13 a and 13b are shown
Single compressed gas source 1380, it is apparent that other gas source, such as oxygen can be provided to patient;And it can be using single
Only source (such as air) controls venturi valve 850.Preferred embodiment for continuous use includes completely disposable suffers from
Person's interface arrangement 16, uses pneumatic shuttle flow disruption valve as shown in the figure, but construct in patient interface connection 470 with
Standard snorkel is used together.When continuous therapeutic device can be used for single patient and usually abandon after a week in continuous use
When, preferably complete disposable system, because infection control prevents from reusing different patients.Do not need patient it
Between carry out disinfection, allow using the low-cost medical grade plastics incompatible with high-temperature sterilization.However, working as reusable part quilt
When being designed to disinfection, it is also possible to using the continuous treatment system of reusable part and single use portion.
As set forth above, it is possible to modify the patient interface device 16 of Figure 13 a and 13b, individual gas is provided for patient with side
It supplies (can be oxygen), and starts shuttle (can be air), therefore reduce the waste of medical oxygen in hospital environment.It is excellent
Selecting embodiment can also include heating element in patient interface device 16, to heat the gas for being supplied to patient.Preferred embodiment
The oxygen that can also be monitored in patient interface device 16 comprising additional sensor in applied treatment, such as sucking gas is dense
It spends score (FiO2).If heating element is embodied as one or more hot lines, this allows each heating element to also serve as hot line
Airspeedometer is to measure gas velocity.Electrical power needed for actuator unit controller 404 also monitors heating element, and can be
The air velocity of the gas passed through is calculated when cooling heating element.Actuator unit controller 404 preferably stores and operates calculation
Method and/or calibration table, preferably include into temperature, reach the gas temperature of patient and the power that is drawn by heating element,
To calculate volume gas flow.Allowed using the second hot wire anemometer by being deposited by electronic controller 404 in expiration port 854
The algorithm of storage and operation calculates the gas volume that patient receives, therefore can observe the air-breathing of patient and circulation of exhaling, and allows to hold
Row vital capacity determination.
Figure 14 a and 14b show the patient interface device 16 of completely disposable Electromagnetically-operating comprising sliding venturi
Valve 850 and external electrical coil 1401, the sliding venturi valve is using the Rare-Earth Magnetic being molded in sliding venturi shuttle ontology 1450
Body 1402, the lateral sliding in disposable shuttle ontology 1460, the external electrical coil are preferably sandwiched in disposable shuttle ontology 1460
Around.Sliding venturi valve 850 accordingly acts as air interruption valve.
Figure 14 a shows the sliding venturi valve 850 in right-hand lay, and air contact maker 1475 is opened.Figure 14 b
The sliding venturi valve 850 in left hand position is shown, and air contact maker 1475 is closed.By a polar DC electric current
The electromagnetic coil 1401 for being applied to external installation forces removable venturi valve 850 to slide in one direction, and reversed polarity
Removable venturi valve 850 is forced to slide along another direction.Since shuttle stroke is usually less than 1/4 inch and shuttle quality most
It is small, therefore shuttle is easy to be up to the speed of 15Hz and rearwardly and a forwardly vibrate.Monitoring electronic equipment energy in electronic controller 404
How electric current in enough detection coils changes as shuttle is mobile, and therefore whether detection shuttle slides, or whether presses step card
Firmly and therefore it is in malfunction.
Preferably, shuttle 1450 has injector 1451, which passes through rigid expanded letter communicating pipe 1453 and feeder house
1452 are in fluid communication, to ensure that the critical distance between injector and venturi inlet 1455 is remained unchanged with shuttle position without
It closes, therefore keeps entrainment appropriate.It is blocked for expanded letter communicating pipe 1453 in the shuttle of left hand position in situ, also serves as air interruption
Valve.In addition, depending on the position of outlet port 1456, adjustable disposable shuttle ontology 1450, so that fully extended shuttle portion
Divide ground or fully occlude expiratory air port 854, to increase mean airway positive pressure (PAP).
Figure 15 a and 15b show the embodiment of another patient interface device 16, are the extensions of Figure 12 a and 12b
Point, wherein it includes the pneumatic bi-directional oscillating air interruption valve 1560 with sliding venturi shuttle 1550.Patient interface device 16
It may include single use portion 1502 and reusable part 1504, be similar to Figure 12 a and 12b.Single use portion 1502 is preferred
Ground includes slidably venturi valve 850, and reusable part 1504 preferably uses Pneumatic double-acting shuttle valve 1570.Figure
15a shows the poppet 1522 of closing, and Figure 15 b shows open poppet 1522 --- pay attention to shuttle valve 1570 and venturi
Valve 850 is connection (for example, by welding poppet 1522 and injection pipe) and moves from one side to the other.If needed
It wants, may respectively be patient's supply and operation shuttle provides individual gas supply 1598,1599.Here, pneumatic shuttle valve 850 is supported
Swinging axle 1512 extends and is in fluid communication with the sliding venturi shuttle 1550 from feeder house 1547.When poppet 1522 is with aforementioned
When mode is opened, 1550 synchronizing moving of shuttle is slided.For the embodiment of Figure 10 a, 10b or Figure 11 a, 11b, phase can be respectively adopted
Same method.
Figure 16 a and 16b show another patient interface device 16, and the electromagnetic sliding valve for combining Figure 14 a and 14b is former
The electromagnetic interrupter of reason and the feature of Figure 10 a, 10b and/or Figure 11 a, 11b.Patient interface device 16 includes as described above
Single use portion 1602 and reusable part 1604.Single use portion 1602 preferably includes the slidably literary of electromagnetic start
Valve 850 in mound, and reusable part 1604 preferably uses the poppet 1622 of electromagnetic start.Figure 16 a shows pass
The poppet 1622 closed, Figure 16 b show open poppet 1622 --- pay attention to shuttle valve 1660 and slidably venturi valve 850
It can independently move.The embodiment provides in terms of the application of surging and the relative timing of sliding venturi valve 850
Maximum flexibility, as shown in the figure.Reusable part 1604 preferably includes solenoid interruption valve 1662 and electromagnetic coil
1663.In the alternative solution similar to Figure 14 a and 14b, coil can be clamped around single use portion 1602, including shell
1630 and slidably venturi valve 850.Furthermore it is possible to completely or partially synchronize occlusion expiratory air using secondary solenoid
Port 854, to maximize nearside patient expiration's positive pressure effect.
Figure 17 a and 17b show another embodiment of compact, completely disposable patient interface device 16.The reality
It applies example and is combined with the sliding venturi valve 850 operated by movable shuttle 1710.Completely disposable patient interface device 16 preferably wraps
Include slidably venturi valve 850 and movable shuttle valve 1740, the modification as Figure 17 a and 17b.This method is prolonging for Figure 13 a and 13b
It stretches, wherein removable shuttle 1710 synchronously starts sliding venturi valve 850 using spring reset 1733 now.Flexural spring 1733
Then providing non-linear effect allows shuttle wherein must reach scheduled 1747 pressure of chamber before spring 1733 provides
1710 slidings suddenly.Air-breather 1790 is shown as with needle-valve 1797 to change duty ratio, which is always adjusted to
Greater than the flow of 1799 needle-valve 1798 of entrance of control frequency.Simplified method can be ventilated using fixed drilling.
Figure 18 a and 18b show another preferred embodiment, and using dual-action forcibly makes slidably venturi valve
850 return, without relying solely on spring pressure.Pneumatically slidably venturi valve 850 preferably uses four needle-valves for double acting
1801,1802,1803,1804 to obtain maximum construction flexibility, and at most using three gas accesses 1821,860,
1823.First gas inlet 860 is used for patient, and can be air, oxygen or the combination in optimal treatment pressure.Second
Gas access 1821 uses two needle-valves 1801,1802 a --- use for sliding venturi valve 850 towards patient
In the accumulation for controlling pressure and slide venturi, another is for ventilating.Third gas entrance 1823 can have and first
The pressure different with second entrance, needle-valve 1803,1804 makes venturi valve 850 to control rate of pressure rise also there are two tool
Original position is returned to, and is ventilated.Four needle-valves and different pressure allow accurate control frequency and duty ratio.Simpler double cropping
It can have the single gas supply to patient and actuator with venturi valve embodiment, and control frequency using single needle-valve
Rate, wherein fixed drilling replaces other needle-valves to set duty ratio or variation (variations) therebetween.
A part of distribution system and one of distribution system in patient interface device 16 in actuator unit 10
The benefit divided includes: that air interruption valve is repositioned onto patient interface device 16 to eliminate the long air column pair connected in hose
The damping effect of surge pulsation, improves hose wall vein compliance and improves efficiency;It reduces to patient and treatment is provided
Property surging needed for system working pressure, reduce system power dissipation and noise;Since patient interface device 16 can be in device
It is simply replaced when end-of-life, without dismantling and retesting actuator unit 10, therefore improves maintenance.
Adaptive dynamic low tide gas ventilation embodiment
Adaptive dynamic low tide gas ventilation embodiment will now be described.About Fig. 8, above description is related to previously described text
Valve in mound, but sliding venturi valve 850 is used to replace previously described venturi valve.
Figure 19 a and 19b show the patient interface device 1600 of completely disposable Electromagnetically-operating comprising slide literary mound
In valve 1850 and external electrical coil 11401, the sliding venturi valve using be molded in sliding venturi shuttle body 11450 in rare earth
Magnet 11402, the lateral sliding in disposable shuttle ontology 11460, the external electrical coil are preferably sandwiched in disposable shuttle ontology
Around 11460.Sliding venturi valve 1850 accordingly acts as air interruption valve.
Figure 19 a shows the sliding venturi valve 1850 in right-hand lay, and air contact maker 11475 is to open
's.Figure 19 b shows the sliding venturi valve 1850 in left hand position, and air contact maker 11475 is closed.By a pole
Property DC electric current be applied to the electromagnetic coil 11401 of external installation removable venturi valve 1850 forced to slide in one direction,
And reversed polarity forces removable venturi valve 1850 to slide along another direction.Since shuttle stroke is usually less than 1/4 inch
And shuttle quality is minimum, therefore shuttle easily can rearwardly and a forwardly be vibrated with the speed for being up to 15Hz.In electronic controller 404
Monitoring electronic equipment be able to detect how the electric current in coil as shuttle is mobile and changes, and therefore detects whether shuttle slides,
Or whether is blocked by step and be therefore in malfunction.
Preferably, shuttle 11450 has injector 11451, which passes through rigid expanded letter communicating pipe 11453 and feeder house
1452 be in fluid communication, with ensure injector and slide venturi inlet 11455 between critical distance remain unchanged and with shuttle position
It sets unrelated, therefore keeps entrainment appropriate.It is blocked for expanded letter communicating pipe 11453 in the shuttle of left hand position in situ, also serves as sky
Gas interruption valve.In addition, depending on the position of outlet port 11456, adjustable disposable shuttle ontology 11450, so that prolonging completely
The shuttle stretched partially or even wholly occludes expiratory air port 854, to increase mean airway positive pressure (PAP).In fact, sliding
Venturi serves as integrated air-breathing, outlet valve.
In operation, when receiving high-pressure pulsating air-flow from interruption valve, venturi ontology is moved away from position of rest (open position
It sets);Simultaneously because Venturi effect, gas, which enters venturi inlet by bar channel and generates flowing, to be accelerated and generates lower than ring
The pressure of border pressure.This promotes gas (from environment, or coming from low tension loop) to be entrained and enter venturi.Because of venturi
There is pipe bigger diameter to restore pressure, and low tidal volumes are transported to trouble so flow will slow down as its delivery port
Person's air flue (Figure 20 a).When its maximum proximal position (occlusion locations) is arrived in driving, block with sliding venturi portion or fully
Exhalation vents port, to reduce the flowing of exhaled gas.When venturi sliding block (is beaten after applying pulsation back to initial position
Open position) when, exhalation vents port fully opens, and gas is allowed to escape (patient expiration).
According to venturi (Venture) theory, when the delivery port of venturi meets obstructions (flow x resistance=pressure)
When, the intrinsic pressure of venturi will increase, and become environmental pressure, and flow entrainment to reduce (Figure 20 b).Therefore, flow
The pressure reached with the horizontal place of air flue is conveyed to be inversely proportional;Therefore, when system is close to required stress level, the ratio of gas is conveyed
Example almost comes from high-pressure pulsating component.
Due to Venturi effect, the flow of conveying is converted into pressure by adapting to thoracic cavity lung resistance (vice versa).This
A little factors allow to optimize assignment of traffic at air flue level, to avoid preferentially ventilating, and allow mean airway pressure opposite
It keeps relative stability in the elasticity and resistance of breathing structure.
In Figure 20 a, V1<V2>V3;And P1>P2<P3.In the flowing acceleration region indicated by arrow Q and R, pressure
It becomes less than environmental pressure and is entrained with gas.In Figure 20 b, when applying resistance (R), venturi design is by reducing stream
Dynamic entrainment is to provide pressure.
In Figure 20 b, theoretical Venturi tube 2001 shows pressure behavior according to the variation of pipe geometry.It is straight when pipe
When diameter reduces at 2003, (Bernoulli effect) will be increased by the flow velocity of limitation, and according to law of conservation of energy, work as generation
When entrainment, pressure must be reduced to 1 from 4, and get lower than environmental pressure P=2.By increasing the diameter of pipe at 2005,
Flow velocity will decline, therefore pressure will be restored.When resistance R is applied to the delivery port of Venturi tube, the pressure in venturi becomes
It is equal with environmental pressure enough to height, and carry secretly and be reduced to zero.
For example, with reference to Figure 19 a and 19b.In operation, when receiving high-pressure pulsating air-flow from interruption valve 11450, venturi
Ontology 1850 is mobile (open position, Figure 19 b) far from position of rest;Meanwhile gas enters venturi inlet by bar channel
11451, it generates flowing and accelerates, and be lower than environmental pressure 11455 since Venturi effect generates.This promotes gas (from ring
Border, or come from low tension loop) carried secretly by 863 and enter venturi.Because Venturi tube has more than its delivery port 11456
Big diameter restores pressure, and low tidal volumes are transported to patient airway so flowing will slow down.When driving to its maximum
When proximal position (occlusion locations), venturi portion or completely obstruction exhalation vents port are slided, to reduce the stream of exhaled gas
Dynamic (Figure 19 a).When venturi sliding block is when returning to initial position (open position) after applying pulsation, exhalation vents port is complete
It is complete to open 854, allow gas to escape (patient expiration) (Figure 19 b).It opens and closes every time and represents a circulation (expiration and suction
Gas);Therefore, if patient is ventilated with the rate of 100-300 or 600 cycles per minutes, mean venturi will open and
Close 100-300 or 600 beat/min.
Figure 21 a and 21b show another 1600 embodiment of patient interface device, are the extensions of Figure 12 a and 12b
Point, wherein it includes the pneumatic bi-directional oscillating air interruption valve 11560 with sliding venturi shuttle 11550.Patient interface device
1600 may include single use portion 11502 and reusable part 11504, be similar to Figure 12 a and 12b.Single use portion
11502 preferably include slidably venturi valve 1850, and reusable part 11504 preferably uses Pneumatic double-acting
Shuttle valve 11570.Figure 20 a shows the poppet 11522 of closing, and Figure 20 b shows open poppet 11522 --- pay attention to shuttle
Valve 11570 and sliding venturi valve 1850 connection (for example, by welding poppet 11522 and injection pipe) are simultaneously mobile from side
To the other side.If desired, may respectively be patient's supply and the individual gas supply 1598,1599 of operation shuttle offer.Here, it props up
The swinging axle 11512 for supportting pneumatic shuttle valve 1850 extends and connects with 11550 fluid of sliding venturi shuttle from feeder house 11547
It is logical.When poppet 11522 is opened in the foregoing manner, 11550 synchronizing moving of shuttle is slided.For Figure 10 a, 10b or Figure 11 a, 11b
Embodiment, identical method can be respectively adopted.In fact, sliding venturi serves as integrated air-breathing, outlet valve.In addition,
Depending on the position of outlet port 11556, adjustable disposable shuttle ontology 11550 so that fully extended shuttle partly or
Expiratory air port 854 is fully occluded, to increase mean airway positive pressure (PAP).In fact, sliding venturi serves as one
Air-breathing, outlet valve.
Figure 22 a and 22b show another patient interface device 1600, combine the electromagnetic sliding valve of Figure 14 a and 14b
Electromagnetic interrupter (the electromagnetic of principle and the feature of Figure 10 a, 10b and/or Figure 11 a, 11b
interrupter).Patient interface device 1600 includes single use portion 11602 as described above and reusable part
11604.Single use portion 11602 preferably includes the sliding venturi valve 1850 of electromagnetic start, and reusable part
11604 preferably use the poppet 11622 of electromagnetic start.Figure 22 a shows the poppet 11622 of closing, and Figure 22 b is shown
The poppet 11622 of opening --- notice that shuttle valve 11660 and sliding venturi valve 1850 can independently move.As shown,
The embodiment provides in terms of the application of adaptive dynamic low tide gas ventilation pulsation and the relative timing of sliding venturi valve 1850
Maximum flexibility.Reusable part 11604 preferably includes solenoid interruption valve 11662 and electromagnetic coil 11663.
In the alternative solution similar to Figure 14 a and 14b, coil can be clamped around single use portion 11602, including shell 11630
With sliding venturi valve 1850.In addition, the position of outlet port 11656 is depended on, adjustable disposable shuttle ontology 11602,
So that fully extended shuttle partially or even wholly occludes expiratory air port 854, to increase mean airway positive pressure (PAP).
In fact, sliding venturi serves as integrated air-breathing, outlet valve.It can be closed using secondary solenoid completely or partially to synchronize
Expiratory air port 854 is filled in, to maximize nearside patient expiration's positive pressure effect.
Another implementation of compact, completely disposable patient interface device 1600 is shown in Figure 23 a and 23b
Example.This embodiment combines the sliding venturi valves 1850 operated by movable shuttle 11710.Complete disposable patient interface device
1600 preferably include sliding venturi valve 1850 and movable shuttle valve 11740, the modification as Figure 17 a and 17b.This method is figure
The extension of 13a and 13b, wherein removable shuttle 11710 synchronously starts sliding venturi valve using spring return 11733 now
1850.Flexural spring 11733 provides non-linear effect, wherein must reach scheduled chamber before spring 11733 provides
Then 11747 pressure allow shuttle 11710 to slide suddenly.Blow vent 11790 is shown as with needle-valve 11797 to change duty ratio,
The duty ratio is always adjusted to be greater than the flow of 11799 needle-valve 11798 of entrance of control frequency.Simplified method can use
Fixed drilling is aerated.In addition, depending on the position of outlet port 11756, sliding venturi valve 1850 will be partly
Or expiratory air port 854 is fully occluded, to increase mean airway positive pressure (PAP).In fact, sliding venturi serves as one
The air-breathing of body, outlet valve.
Figure 24 a and 24b show another preferred embodiment, and using double acting forcibly makes slidably venturi valve
1850 return, and do not depend solely on spring pressure.Pneumatically slidably venturi valve 1850 preferably uses four for double acting
Needle-valve 11801,11802,11803,11804 at most uses three gas accesses to obtain maximum construction flexibility
11821,1860,11882.First gas inlet 860 is used for patient, and can be air, oxygen or be in optimal treatment pressure
The combination of power.Second gas inlet 11821 uses two needle-valves for sliding venturi valve 1850 towards patient
11801,11802 --- one is used to control the accumulation of pressure and slides venturi, another is for ventilating.Third gas enters
Mouth 11823 can have the pressure different from the first and second entrances, and also there are two needle-valves 11803,11804 for tool, to control pressure
Power climbing speed makes sliding venturi valve 1850 return to original position, and ventilates.Four needle-valves and different pressure allow accurate
Control frequency and duty ratio.Simpler double acting sliding venturi valve embodiment can have to the single of patient and actuator
Gas supply, and controls frequency using single needle-valve, wherein fixed drilling set instead of other needle-valves duty ratio or its
Between variation (variations).In addition, depending on the position of outlet port 11856, sliding venturi valve 1850 will portion
Divide ground or fully occlude expiratory air port 854, to increase mean airway positive pressure (PAP).In fact, sliding venturi fills
Air-breathing, outlet valve when one.
Although describing the present invention about the content for being presently believed to be preferred embodiment, it should be appreciated that, this
Invention is not limited to the disclosed embodiments.On the contrary, including in the spirit and scope of the appended claims the present invention is directed to cover
Various modifications and equivalent arrangements.Scope of the appended claims should be endowed broadest interpretation, to repair comprising all these
Change and equivalent structure and function.
It is shown in the accompanying drawings with profile or is all well-known in patient ventilation field by all parts that block indicates,
And their specific structure and operation are not important for implementing operation or optimal mode of the invention.
All U.S. discussed above and foreign patent and patent application are all incorporated by reference into the detailed of preferred embodiment
In thin description.
Claims (20)
1. a kind of for conveying the equipment that impinging air is pulsed to patient comprising:
At least one actuator unit, at least one described actuator unit are configured to provide pressurization, non-fluctuating gas;
At least one patient interface device, at least one described patient interface device have structure, and the structure is configured to:
(i) pressurization, non-fluctuating gas is received from least one described actuator unit, and converted thereof into pulsation and pressurization
Gas;(ii) by patient connect aperture to patient supply at least one low tidal volumes pulsation and pressurization gas;With
And
At least one flexible pipe, at least one described flexible pipe be configured to from least one described actuator unit to it is described at least
One patient interface device provides pressurization, non-fluctuating gas.
2. equipment according to claim 1, wherein (i) at least one described actuator unit, (ii) it is described at least one
Patient interface device, and at least one flexible pipe described in (iii) are configured to logical to the adaptive dynamic low tide gas of patient's offer
Gas air impulsive motion.
3. equipment according to claim 2, wherein at least one described patient interface device is repeatable at least one
Use part.
4. equipment according to claim 3, wherein at least one described patient interface device has at least one sliding text
Valve in mound, it is described at least one sliding venturi valve be configured to: (i) from least one described gas halts valve receive pulsation and
The air-flow of pressurization, (ii) by pulsation and pressurization gas be converted at least one low tidal volumes pulsation and pressurization gas
The pulsation of at least one low tidal volumes and pressurization gas is transported to patient and connects aperture, and (iv) by body, (iii)
It is integrally operated as air-breathing, outlet valve, wherein the expiration of a low tidal volumes will be followed after the conveying of each low tidal volumes.
5. equipment according to claim 1, wherein at least one described patient interface device has at least one disposable
Part.
6. equipment according to claim 1, wherein at least one described patient interface device is repeatable at least one
Use part.
7. equipment according to claim 1, wherein at least one described patient interface device has at least one gas
Disconnected valve, at least one described gas halts valve are configured to by the pressurization, non-fluctuating gas is converted into pulsation and pressurization
Air-flow.
8. equipment according to claim 7, wherein at least one described patient interface device has at least one venturi
Valve, at least one described venturi valve are configured to: (i) receives pulsation and pressurization gas from least one described gas halts valve
Stream, (ii) by pulsation and pressurization gas be converted at least one low tidal volumes pulsation and pressurization gas, and (iii)
The pulsation of at least one low tidal volumes and pressurization gas is transported to patient and connects aperture.
9. equipment according to claim 1 further includes being configured to be detachably connected to the patient interface device
At least one quickly disconnect device, it is described at least one quickly to disconnect device include: (i) at least one electric connector;
(ii) at least one flexible pipe connector, at least one described flexible pipe connector are configured to carrying pressurization, non-fluctuating
Gas.
10. a kind of patient interface device conveys impinging air pulsation to patient for connecting aperture by patient, the patient is connect
Mouthful device includes:
At least one gas access, at least one described gas access are configured to receive gas pressurize, non-fluctuating;
At least one gas halts valve, at least one described gas halts valve are configured to receive from actuator unit pressurization, non-
The gas of pulsation, and convert thereof into pulsation and pressurization gas;And
At least one sliding venturi valve, at least one described sliding venturi valve are configured to: (i) is from least one described gas
Interruption valve receives pulsation and pressurization air-flow, and pulsation and pressurization gas is converted at least one low tidal volumes by (ii)
The pulsation of at least one low tidal volumes and pressurization gas is transported to trouble by pulsation and pressurization gas, and (iii)
Person connects aperture.
11. device according to claim 10, wherein the sliding venturi valve is configured to (iv) as air-breathing, outlet valve
One operation, wherein the expiration of a low tidal volumes will be followed after the conveying of each low tidal volumes.
12. device according to claim 10, wherein at least one the described gas access (i), (ii) it is described at least one
Gas halts valve, and (iii) described sliding venturi valve are configured to provide adaptive dynamic low tide gas ventilation sky to patient
Gaseous pulse is dynamic.
13. device according to claim 10, wherein at least one described sliding venturi valve and patient's connecting hole
Mouth is disposable.
14. device according to claim 13, wherein at least one described gas halts valve is reusable.
15. a kind of actuator unit for impact type patient treatment comprising:
At least one gas access, at least one described gas access are configured to provide at least one pressure vessel at least one
Pressurization, non-fluctuating gas, at least one described pressure vessel construction is at storage at least one pressurization, non-fluctuating
Gas;
At least one gas vent, at least one described gas vent be configured to from the actuator unit export stored to
A kind of few pressurization, non-fluctuating gas;And
At least one electronic controller, at least one described electronic controller are configured to: (i) is filled from least one patient interface
Set reception signal;(ii) controls the operation of at least one pressure vessel.
16. unit according to claim 15, wherein at least one the described gas access (i), (ii) it is described at least one
Gas vent, and at least one electronic controller described in (iii) are configured to logical to the adaptive dynamic low tide gas of patient's offer
Gas air impulsive motion.
17. a kind of provide the equipment that adaptive dynamic low tide gas is ventilated to patient comprising:
At least one gas access, at least one described gas access are configured to provide at least one pressure vessel at least one
Pressurization, non-fluctuating gas, at least one described pressure vessel construction is at storage at least one pressurization, non-fluctuating
Gas;
At least one gas vent, at least one described gas vent are configured to export from least one described pressure vessel and be deposited
At least one pressurization of storage, non-fluctuating gas;With
At least one electronic controller, at least one electronic controller construction are as follows: (i) is received from patient interface device to be believed
Number;(ii) controls the operation of at least one pressure vessel;
At least one flexible pipe, at least one described flexible pipe is configured to will be from the pressurization of at least one gas vent
, non-fluctuating gas be supplied to the patient interface device;And
The patient interface device includes:
At least one patient interface gas access, at least one described patient interface gas access be configured to from it is described at least one
Flexible pipe receives pressurization, non-fluctuating gas;
Patient interface device gas halts valve, the patient interface device gas halts valve are configured to from the patient interface device
Gas access receives pressurization, non-fluctuating gas, and converts thereof into pulsation and pressurization gas;With
At least one sliding venturi valve, at least one described sliding venturi valve are configured to: (i) is from the patient interface device
Gas halts valve receives pulsation and pressurization air-flow;(ii) pulsation and pressurization gas is converted at least one low tide gas
The pulsation of amount and pressurization gas;(iii) conveys the pulsation of at least one low tidal volumes and pressurization gas
Aperture is connected to patient interface device patient.
18. equipment according to claim 17, wherein at least one described electronic controller is connected to the patient interface
Device.
19. equipment according to claim 17, wherein it is disposable that the patient interface device patient, which connects aperture,.
20. a kind of provide the method that adaptive dynamic low tide gas is ventilated to patient comprising:
At least one pressurization, non-fluctuating gas is provided at least one pressure vessel;
Come using at least one electronic controller: (i) receives signal from patient interface device;(ii) control it is described at least one
The operation of pressure vessel;
Pressurization, non-fluctuating gas is provided from least one described pressure vessel to the trouble using at least one flexible pipe
Person's interface arrangement;
The pressurization from least one flexible pipe, non-fluctuating gas is received using patient interface device gas access;
Pressurization, non-fluctuating gas is received from the patient interface device gas access using patient interface device gas halts valve
Body, and convert thereof into pulsation and pressurization gas;And
Slide venturi valve using at least one: (i) is received pulsing and is added from the patient interface device gas halts valve
The air-flow of pressure;(ii) pulsation and pressurization gas is converted into the pulsation of at least one low tidal volumes and pressurization gas;
The pulsation of at least one low tidal volumes and pressurization gas is transported to patient interface device patient's connecting hole by (iii)
Mouthful.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201662369954P | 2016-08-02 | 2016-08-02 | |
US62/369,954 | 2016-08-02 | ||
PCT/US2017/043354 WO2018026549A1 (en) | 2016-08-02 | 2017-07-21 | Apparatus for providing percussive ventilation therapy to a patient airway |
Publications (2)
Publication Number | Publication Date |
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CN109803704A true CN109803704A (en) | 2019-05-24 |
CN109803704B CN109803704B (en) | 2022-06-03 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201780061035.8A Active CN109803704B (en) | 2016-08-02 | 2017-07-21 | Apparatus for providing percussive ventilation therapy to a patient's airway |
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Country | Link |
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US (1) | US10987274B2 (en) |
EP (1) | EP3493870B1 (en) |
CN (1) | CN109803704B (en) |
FI (1) | FI3493870T3 (en) |
WO (1) | WO2018026549A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110433366A (en) * | 2019-08-12 | 2019-11-12 | 杭州市红十字会医院 | A kind of portable drug delivery device for respiratory medicine |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018007997A1 (en) | 2016-07-08 | 2018-01-11 | Trudell Medical International | Smart oscillating positive expiratory pressure device |
EP3551261B1 (en) * | 2016-12-09 | 2022-05-11 | Trudell Medical International | Smart nebulizer |
MX2020007026A (en) | 2018-01-04 | 2020-12-03 | Trudell Medical Int | Smart oscillating positive expiratory pressure device. |
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JP7179407B2 (en) * | 2019-03-13 | 2022-11-29 | マグナメド テクノロジア メディカ エスィ/アー | transport ventilator |
TR201904781A2 (en) * | 2019-03-29 | 2020-10-21 | T C Trakya Ueniversitesi | MICROPROCESSOR CONTROLLED ELECTRO PNEUMATIC SOLUTION REHABILITATION DEVICE |
WO2021038467A1 (en) * | 2019-08-27 | 2021-03-04 | Trudell Medical International | Smart oscillating positive expiratory pressure device |
US10934902B1 (en) * | 2019-11-06 | 2021-03-02 | Caterpillar Inc. | Valve seat insert for high power density and marine engines |
WO2022203944A1 (en) * | 2021-03-25 | 2022-09-29 | Bougatef Adel | Method and apparatus for providing percussive ventilation therapy to a patient airway |
CA3177352A1 (en) * | 2022-02-11 | 2023-08-11 | Fisher & Paykel Healthcare Limited | Positive pressure breathing circuit |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050061318A1 (en) * | 2003-09-22 | 2005-03-24 | Faram Joseph Dee | Continuous high-frequency oscillation breathing treatment apparatus |
CN101622036A (en) * | 2006-11-13 | 2010-01-06 | 阿利吉安斯公司 | Respiratory therapy apparatus and method |
CN102316936A (en) * | 2007-11-19 | 2012-01-11 | 护理联合2200公司 | Respiratory therapy system with electromechanical driver |
CN104334080A (en) * | 2012-05-22 | 2015-02-04 | 皇家飞利浦有限公司 | Cough assistance and measurement system and method cross-reference to related applications |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1138274A (en) * | 1966-03-04 | 1968-12-27 | Liston Fletcher Inc | Therapeutic respirator |
US4118611A (en) | 1977-08-30 | 1978-10-03 | International Business Machines Corporation | Buckling spring torsional snap actuator |
US4197843A (en) | 1978-04-03 | 1980-04-15 | Minnesota Mining And Manufacturing Company | Volume limiting ventilator |
US5862802A (en) | 1981-04-03 | 1999-01-26 | Forrest M. Bird | Ventilator having an oscillatory inspiratory phase and method |
US4592349A (en) | 1981-08-10 | 1986-06-03 | Bird F M | Ventilator having an oscillatory inspiratory phase and method |
US6920875B1 (en) * | 1999-06-15 | 2005-07-26 | Respironics, Inc. | Average volume ventilation |
US6595203B1 (en) | 2000-11-28 | 2003-07-22 | Forrest M. Bird | Apparatus for administering intermittent percussive ventilation and unitary breathing head assembly for use therein |
US6581600B2 (en) | 2001-07-13 | 2003-06-24 | Forrest M. Bird | Interface apparatus and combination and method |
US7210479B2 (en) | 2003-11-07 | 2007-05-01 | Van Den Akker Erik | Hyperoxic breathing system |
US8051854B2 (en) * | 2006-09-15 | 2011-11-08 | Comedica Incorporated | Continuous high-frequency oscillation breathing treatment apparatus |
RU2448742C2 (en) | 2007-04-02 | 2012-04-27 | Эллидженс Корпорейшн | High-frequency oscillating respiratory therapeutic device |
US8347883B2 (en) | 2008-11-17 | 2013-01-08 | Bird F M | Manual controlled bi-phasic intrapulmonary percussive ventilation and methods |
US9114219B2 (en) | 2008-11-19 | 2015-08-25 | Koninklijke Philips N.V. | Insufflating-exsufflating system |
US20120318261A1 (en) * | 2011-06-17 | 2012-12-20 | Nostrum Technology Llc | Valved Holding Chamber With Whistle for the Administration of Inhalable Drugs |
WO2013068918A1 (en) | 2011-11-07 | 2013-05-16 | Koninklijke Philips Electronics N.V. | Systems and methods for intra-pulmonary percussive ventilation integrated in a ventilator |
-
2017
- 2017-07-21 US US15/656,818 patent/US10987274B2/en active Active
- 2017-07-21 EP EP17749002.6A patent/EP3493870B1/en active Active
- 2017-07-21 FI FIEP17749002.6T patent/FI3493870T3/en active
- 2017-07-21 WO PCT/US2017/043354 patent/WO2018026549A1/en unknown
- 2017-07-21 CN CN201780061035.8A patent/CN109803704B/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050061318A1 (en) * | 2003-09-22 | 2005-03-24 | Faram Joseph Dee | Continuous high-frequency oscillation breathing treatment apparatus |
CN101622036A (en) * | 2006-11-13 | 2010-01-06 | 阿利吉安斯公司 | Respiratory therapy apparatus and method |
CN102316936A (en) * | 2007-11-19 | 2012-01-11 | 护理联合2200公司 | Respiratory therapy system with electromechanical driver |
CN104334080A (en) * | 2012-05-22 | 2015-02-04 | 皇家飞利浦有限公司 | Cough assistance and measurement system and method cross-reference to related applications |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110433366A (en) * | 2019-08-12 | 2019-11-12 | 杭州市红十字会医院 | A kind of portable drug delivery device for respiratory medicine |
CN110433366B (en) * | 2019-08-12 | 2022-03-04 | 杭州市红十字会医院 | Portable department of respiration ware of dosing |
Also Published As
Publication number | Publication date |
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US20180036199A1 (en) | 2018-02-08 |
FI3493870T3 (en) | 2023-09-11 |
CN109803704B (en) | 2022-06-03 |
EP3493870B1 (en) | 2023-06-21 |
WO2018026549A1 (en) | 2018-02-08 |
US10987274B2 (en) | 2021-04-27 |
EP3493870A1 (en) | 2019-06-12 |
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