CN109793695A - A kind of skin barrier repair cream and preparation method thereof - Google Patents

A kind of skin barrier repair cream and preparation method thereof Download PDF

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Publication number
CN109793695A
CN109793695A CN201910190561.5A CN201910190561A CN109793695A CN 109793695 A CN109793695 A CN 109793695A CN 201910190561 A CN201910190561 A CN 201910190561A CN 109793695 A CN109793695 A CN 109793695A
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China
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parts
extract
skin barrier
mixture
minutes
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CN201910190561.5A
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Chinese (zh)
Inventor
黄惠先
曾宇和
张丽婕
江华初
陈鑫隆
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Guangzhou Cohen Biotechnology Co Ltd
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Guangzhou Cohen Biotechnology Co Ltd
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Priority to CN201910190561.5A priority Critical patent/CN109793695A/en
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Abstract

The invention discloses a kind of skin barrier repair creams and preparation method thereof, are made of following material quality part: 2-4 parts of cetearyl glucoside, 1-2 parts of cetostearyl alcohol, 5-6 parts of jojoba oil, 2-5 parts of olive oil, -5 parts of Cer EOS, 1-10 parts of cholesterol, 2-3 parts of isopropyl palmitate, 1-3 parts of lanolin, 1-5 parts of isononyl isononanoate, 3-5 parts of glycerol, 1-20 parts of Chinese medicinal plant extract, 3-5 parts of butanediol, 0.5-2 parts of Sodium Hyaluronate, 1-5 parts of niacinamide, 0.2-2 parts of thickener, 0.5-2 parts of decoyl hydroximic acid, 16-74.8 parts of rose wate.Preparation method: mixing insulated and stirred for part material and obtain two kinds of mixtures, and two kinds of mixtures are then mixed insulated and stirred and obtain third mixture, adds Chinese medical extract and decoyl hydroximic acid, ceramide, cholesterol are mixed discharging and obtain finished product.The present invention can enhance reparation skin barrier.

Description

A kind of skin barrier repair cream and preparation method thereof
Technical field
The present invention relates to cosmetic technical fields more particularly to a kind of skin barrier repair cream and preparation method thereof.
Background technique
The stable state of skin barrier is a complicated network regulation process, and growth, differentiation comprising Skin Cell are immunized instead It answers and a variety of pathophysiological processes such as inflammation, extremely most skin barrier caused by environmental factor is secondary to dermatitis The consequence that disease, epidermal proliferation are unbalance with differentiation.Skin barrier damage, can be conducive to the invasion of allergen and microorganism, dermatitis Disease reaction aggravates.Lipid is mainly made of ceramide, free fatty acid and cholesterol between skin keratinocytes.According to skin Composition, one is suitable for improving the repair cream of skin barrier function, it should have barrier maintenance, barrier reparation, barrier enhancing, will swim Combine from lipid, struetural lipid, active constituent these raw materials, is suitable for repairing skin barrier.
The present invention passes through maintenance barrier, repairs barrier, enhancing barrier, these originals of lipid, struetural lipid, active constituent of dissociating Material combines, by different regions, the consumer of all ages and classes, according to different people cutaneous gene examining report, skin physiology, Situation, season, age, the dimension scientific design customization skin care scheme of region seven and preparation have instantly for dermatopathology, skin The repair cream of skin barrier function is repaired very well.
Summary of the invention
In view of the deficiencies of the prior art, technical problem solved by the invention is how to repair skin barrier.
In order to solve the above technical problems, the technical solution adopted by the present invention is that a kind of skin barrier repair cream, by following original Material mass parts be made: 2-4 parts of cetearyl glucoside, 1-2 parts of cetostearyl alcohol, 5-6 parts of jojoba oil, 2-5 parts of olive oil, - 5 parts of Cer EOS, cholesterol 1-10,2-3 parts of isopropyl palmitate, 1-3 parts of lanolin, 1-5 parts of isononyl isononanoate, glycerol 3-5 parts, 1-20 parts of Chinese medicinal plant extract, 3-5 parts of butanediol, 0.5-2 parts of Sodium Hyaluronate, 1-5 parts of niacinamide, thickener 0.2-2 parts, 0.5-2 parts of decoyl hydroximic acid, 16-74.8 parts of rose wate.
Further, the Chinese medicinal plant extract is: dendrobium candidum extract, Herba Saussureae Involueratae extract, ginseng extract At least one of object, Black Ganoderma extract.
Further, the Chinese medicinal plant extract is made of following material quality part: dendrobium candidum extract 10-40 Part, 10-40 parts of Saussurea involucrata extract, 10-40 parts of ginseng root extract, 10-40 parts of Black Ganoderma extract.
Further, the thickener is: carbomer, xanthan gum, hydroxyethyl cellulose, Scleroglucan, Sodium Polyacrylate, Acrylic acid (ester) class/C10-30 alcohol acrylate crosspolymers sodium at least one.
The invention solves another technical problem be to provide the preparation method of above-mentioned skin barrier repair cream.
For this purpose, technical solution provided by the invention is a kind of skin barrier repair cream preparation method, comprising the following steps:
(1) rose wate of formula ratio, glycerol, butanediol, Sodium Hyaluronate, Sodium Polyacrylate are put into kettle, It is heated to 80-85 degrees Celsius, insulated and stirred 10 minutes, obtains the first mixture;
(2) by the cetearyl glucoside of formula ratio, cetostearyl alcohol, jojoba oil, olive oil, palmitinic acid isopropyl Ester, lanolin, isononyl isononanoate are put into oil cauldron, are heated to 80-85 degrees Celsius, insulated and stirred 10 minutes, are obtained second Mixture;
(3) the first mixture, the second mixture are evacuated in emulsion pot, homogeneous 10 minutes, insulated and stirred 20 minutes, are obtained Third mixture.
(4) third mixture is cooled to 45 degrees Celsius, Chinese medical extract and decoyl hydroximic acid, ceramide, gallbladder is added Sterol continues stirring 15 minutes, discharges after detection physical and chemical index is qualified.
Compared with prior art, the invention has the benefit that
(1) the Chinese medicinal plant extract used is made, applied to can be reduced group in sensitive skin repair series skin product Amine release inhibits hyaluronidase activity, and Chinese medicinal plant extracts the irritation for reducing skin care item, have it is mild, releive and repair skin The effect of skin barrier function.
(2) dendrobium candidum extract derives from green natural Chinese medicine class plant in the Chinese medicinal plant extract used, belongs to Very mild bioactive substance, active component content is high, is added not only nonirritant in cosmetics but also has moisture retention.
(3) the pure natural product that Herba Saussureae Involueratae extract is extracted from lanatechead saussurea herb with flower in the Chinese medicinal plant extract used, can Interior free yl, effective delaying skin aging are removed, while percutaneous absorption can be helped and lock moisture, long-acting moisturizing avoids Dry skin is coarse.
(4) its energy delay skin aging of ginseng root extract in the Chinese medicinal plant extract used, prevents dry skin de- Water, increases the elasticity of skin, to play the role of protecting skin gloss tender, prevents and reduce wrinkle of skin, ginseng activity Substance also has the reducing property for inhibiting melanin, keeps skin pure white smooth.
(5) polysaccharide, the polypeptide etc. that Black Ganoderma extract has in the Chinese medicinal plant extract used, which have, significantly delays Aging effect.Promote and adjust immune function.Metabolic balance is adjusted, the synthesis of nucleic acid and protein is promoted.Ganoderma lucidum polysaccharide has aobvious The quasi- SOD activity write, can significantly remove the free radical of body generation, to prevent damage of the free radical to body, it is therefore prevented that rouge The peroxidating of body, protects cell, has delayed cell ageing.
Specific embodiment
A specific embodiment of the invention is further described below with reference to embodiment, but is not to limit of the invention It is fixed.
Embodiment 1:
A kind of skin barrier repair cream, is made of following material quality part: 2.2 parts of cetearyl glucoside, spermaceti are hard 1.2 parts of lipidol, 5.1 parts of jojoba oil, 2.3 parts of olive oil .0 parts of Cer EOS, 1.0 parts of cholesterol, isopropyl palmitate 2 Part, 1.5 parts of lanolin, 2 parts of isononyl isononanoate, 3 parts of glycerol, 1 part of Chinese medicinal plant extract, 4 parts of butanediol, Sodium Hyaluronate 0.5 part, 1 part of niacinamide, 0.24 part of Sodium Polyacrylate, 0.8 part of decoyl hydroximic acid, 71.16 parts of rose wate.
Further, the Chinese medicinal plant extract is made of following material quality part: 40 parts of dendrobium candidum extract, snow 10 parts of lotus extract, 10 parts of ginseng root extract, 40 parts of Black Ganoderma extract.
Embodiment 2:
A kind of skin barrier repair cream, is made of following material quality part: 3 parts of cetearyl glucoside, cetearyl alcohol 1.5 parts of alcohol, 5 parts of jojoba oil, 3 parts of olive oil, Cer NP part, 1.5 parts of cholesterol, 2 parts of isopropyl palmitate, lanolin 2 Part, 3 parts of isononyl isononanoate, 3 parts of glycerol, 12 parts of Chinese medicinal plant extract, 4 parts of butanediol, 0.5 part of Sodium Hyaluronate, nicotinoyl 2 parts of amine, 0.4 part of Sodium Polyacrylate, 1 part of decoyl hydroximic acid, 53.1 parts of rose wate.
Further, the Chinese medicinal plant extract is made of following material quality part: 32 parts of dendrobium candidum extract, snow 16 parts of lotus extract, 25 parts of ginseng root extract, 27 parts of Black Ganoderma extract.
Embodiment 3:
A kind of skin barrier repair cream, is made of following material quality part: 3.2 parts of cetearyl glucoside, spermaceti are hard 1.2 parts of lipidol, 5.5 parts of jojoba oil, 3 parts of olive oil, 5.0 parts of ceramide, 10 parts of cholesterol, 2 parts of isopropyl palmitate, sheep Hair 2.5 parts of rouge, 2 parts of isononyl isononanoate, 3 parts of glycerol, 20 parts of Chinese medicinal plant extract, 4.5 parts of butanediol, Sodium Hyaluronate 2 Part, 5 parts of niacinamide, 0.35 part of Sodium Polyacrylate, 0.8 part of decoyl hydroximic acid, 29.95 parts of rose wate.
Further, the Chinese medicinal plant extract is made of following material quality part: 10 parts of dendrobium candidum extract, snow 40 parts of lotus extract, 40 parts of ginseng root extract, 10 parts of Black Ganoderma extract.
1 to 3 preparation method of above-described embodiment, is made up of following steps:
(1) rose wate of formula ratio, glycerol, butanediol, Sodium Hyaluronate, Sodium Polyacrylate are put into kettle, It is heated to 80-85 degrees Celsius, insulated and stirred 10 minutes, obtains the first mixture;
(2) by the cetearyl glucoside of formula ratio, cetostearyl alcohol, jojoba oil, olive oil, palmitinic acid isopropyl Ester, lanolin, isononyl isononanoate are put into oil cauldron, are heated to 80-85 degrees Celsius, insulated and stirred 10 minutes, are obtained second Mixture;
(3) the first mixture, the second mixture are evacuated in emulsion pot, homogeneous 10 minutes, insulated and stirred 20 minutes, are obtained Third mixture.
(4) third mixture is cooled to 45 degrees Celsius, Chinese medical extract and decoyl hydroximic acid, ceramide, gallbladder is added Sterol continues stirring 15 minutes, discharges after detection physical and chemical index is qualified.
Beneficial effect in order to better illustrate the present invention repairs serial cosmetics for skin barrier, and use is distinctive Cosmetic industry evaluation method is to the both effectiveness progress test analysis experiment of the present invention.
Experimental method: filtering out at least 10 faces as crowd (18~45 years old) that skin barrier is damaged and be used as volunteer, It was surveyed respectively at the 0th day, the 7th day and the 14th day after composition of the embodiment of the present invention is smeared by face by blank control Examination, after surveying its skin moisture content, skin water loss amount is used to evaluate skin barrier function and using product, the reparation of skin Ability.
The experiment recruits volunteer 20 altogether, and effective volunteer is 20 and data are effective.Test has carried out 2 weeks altogether, Using skin moisture content, skin water loss amount is detected before and after sample, compare its difference, as a result respectively such as 1~2 institute of table Show.
1 skin moisture content table of table:
Experimental result: compared with control sides, after sample 2 weeks, the skin moisture content of sample side has apparent increase.
2 skin water loss table of table:
Experimental result: compared with compareing and surveying, after sample 2 weeks, the skin water loss of sample side is decreased obviously.
By experimental result as can be seen that the cosmetics prepared using the present composition, moisture content of skin is obvious after 2 weeks Enhancing and skin water loss amount obviously drop, it will be apparent that increase and repaired skin barrier.
Detailed description is made that embodiments of the present invention in conjunction with the embodiments above, but the present invention be not limited to it is described Embodiment.To those skilled in the art, without departing from the principles and spirit of the present invention, to these realities The mode of applying carries out various change, modification, replacement and variant are still fallen in protection scope of the present invention.

Claims (5)

1. a kind of skin barrier repair cream, which is characterized in that be made of following material quality part: cetearyl glucoside 2-4 Part, 1-2 parts of cetostearyl alcohol, 5-6 parts of jojoba oil, 2-5 parts of olive oil, -5 parts of Cer EOS, cholesterol 1-10, palmitinic acid 2-3 parts of isopropyl ester, 1-3 parts of lanolin, 1-5 parts of isononyl isononanoate, 3-5 parts of glycerol, 1-20 parts of Chinese medicinal plant extract, fourth two 3-5 parts of alcohol, 0.5-2 parts of Sodium Hyaluronate, 1-5 parts of niacinamide, 0.2-2 parts of thickener, 0.5-2 parts of decoyl hydroximic acid, rose 16-74.8 parts of water.
2. skin barrier repair cream according to claim 1, which is characterized in that the Chinese medicinal plant extract is: iron sheet At least one of Herba Dendrobii extract, Herba Saussureae Involueratae extract, ginseng root extract, Black Ganoderma extract.
3. skin barrier repair cream according to claim 2, which is characterized in that the Chinese medicinal plant extract is by following original Expect mass parts composition: 10-40 parts of dendrobium candidum extract, 10-40 parts of Saussurea involucrata extract, 10-40 parts of ginseng root extract, black spirit 10-40 parts of sesame extract.
4. skin barrier repair cream according to claim 1, which is characterized in that the thickener is: carbomer, xanthan Glue, hydroxyethyl cellulose, Scleroglucan, Sodium Polyacrylate, acrylic acid (ester) class/C10-30 alcohol acrylate crosspolymers sodium At least one.
5. a kind of preparation method of such as described in any item skin barrier repair creams of Claims 1-4, which is characterized in that including Following steps:
(1) rose wate of formula ratio, glycerol, butanediol, Sodium Hyaluronate, Sodium Polyacrylate are put into kettle, is heated To 80-85 degrees Celsius, insulated and stirred 10 minutes, the first mixture is obtained;
(2) by the cetearyl glucoside of formula ratio, cetostearyl alcohol, jojoba oil, olive oil, isopropyl palmitate, sheep Hair rouge, isononyl isononanoate are put into oil cauldron, are heated to 80-85 degrees Celsius, insulated and stirred 10 minutes, are obtained the second mixing Object;
(3) the first mixture, the second mixture are evacuated in emulsion pot, homogeneous 10 minutes, insulated and stirred 20 minutes, obtain third Mixture.
(4) third mixture is cooled to 45 degrees Celsius, Chinese medical extract and decoyl hydroximic acid, ceramide, cholesterol is added, Continue stirring 15 minutes, discharges after detection physical and chemical index is qualified.
CN201910190561.5A 2019-03-13 2019-03-13 A kind of skin barrier repair cream and preparation method thereof Withdrawn CN109793695A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110123717A (en) * 2019-06-06 2019-08-16 广州市裕朝化妆品有限公司 It is a kind of for repairing the face cream of skin barrier
CN111728894A (en) * 2020-05-21 2020-10-02 娇时日化(杭州)股份有限公司 Protective cream and preparation process thereof
CN112245381A (en) * 2020-11-12 2021-01-22 珂蓝(重庆)化妆品有限公司 Skin care product capable of resisting oxidation and improving skin defense capacity
CN113143805A (en) * 2021-03-25 2021-07-23 无锡简玺生物科技有限公司 Active composition for improving skin barrier function and preparation method thereof
FR3110424A1 (en) * 2020-05-19 2021-11-26 Aime Inc. Food supplement comprising lactic acid bacteria and Reishi extracts
CN114191357A (en) * 2021-11-17 2022-03-18 广州睿森生物科技有限公司 Anti-fatigue composition and application thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110123717A (en) * 2019-06-06 2019-08-16 广州市裕朝化妆品有限公司 It is a kind of for repairing the face cream of skin barrier
FR3110424A1 (en) * 2020-05-19 2021-11-26 Aime Inc. Food supplement comprising lactic acid bacteria and Reishi extracts
CN111728894A (en) * 2020-05-21 2020-10-02 娇时日化(杭州)股份有限公司 Protective cream and preparation process thereof
CN111728894B (en) * 2020-05-21 2023-01-03 娇时日化(杭州)股份有限公司 Protective cream and preparation process thereof
CN112245381A (en) * 2020-11-12 2021-01-22 珂蓝(重庆)化妆品有限公司 Skin care product capable of resisting oxidation and improving skin defense capacity
CN113143805A (en) * 2021-03-25 2021-07-23 无锡简玺生物科技有限公司 Active composition for improving skin barrier function and preparation method thereof
CN114191357A (en) * 2021-11-17 2022-03-18 广州睿森生物科技有限公司 Anti-fatigue composition and application thereof

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Application publication date: 20190524