CN109793224A - It is a kind of for improving the preparation and its application of the substance of skin skin quality - Google Patents
It is a kind of for improving the preparation and its application of the substance of skin skin quality Download PDFInfo
- Publication number
- CN109793224A CN109793224A CN201711140043.XA CN201711140043A CN109793224A CN 109793224 A CN109793224 A CN 109793224A CN 201711140043 A CN201711140043 A CN 201711140043A CN 109793224 A CN109793224 A CN 109793224A
- Authority
- CN
- China
- Prior art keywords
- seeds
- rubber tree
- skin
- unsaponifiable matter
- fatty contents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a kind of preparation of the unsaponifiable matter of seeds of rubber tree fatty contents and its is improving the application in skin skin quality.Substance of the invention is the unsaponifiable matter of the fatty contents of the seed of rubber tree, can be applied to health food, food, in cosmetics, the improvement for skin skin quality.It can be obtained good tender skin effect by eating the health food for being added to the substance, food or being applied directly to skin.
Description
Technical field
The invention belongs to beauty product fields.Specifically, the present invention relates to a kind of substance (rubbers that can improve skin skin quality
The unsaponifiable matter of gum seed fatty contents) and its application.
Background technique
Everybody has a love of beauty, with people's substance, the level of cultural life continuous improvement and society progress,
Skin care is increasingly paid close attention to by people, who has been intended to thin white, lubrication, flexible skin.However, nowadays with life cycle
The change in border and habit, operating pressure is big, radiation increases, diet is unhealthy etc., causes various skin problems, such as dark
Huang, color spot, wrinkle, pore are coarse etc., not only influence beautiful, and serious person can also impact its psychology.
Skin is divided into epidermis, skin corium and three layers of subcutaneous tissue.Epidermis is the outermost layer of skin, rises and protects to human body
Shield, immunization.The living cells of basal layer in epidermis positioned at bottommost constantly can grow and divide, and slowly up push away
Into most surface layer is reached, updates human skin and drain some wastes.And skin corium not only acts as and conveys nutrients to epidermis
The effect of matter, while the fibroblast of skin corium can be metabolized production collagen, elastomer albumen, the cell repair factor
Deng, make skin keep elasticity, moisten, prevent aging.However as the growth at human body age, fibroblast quantity can be reduced,
Secrete collagen, the ability decline of elastomer etc..Therefore skin will appear loose, coarse, flexibility decrease, wrinkle increases
Deng.
For many years, it is improvement skin skin quality, keeps skin soft, it is flexible.Successively there is product and the side of many tender skins
Method.It common are following several:
1. skin care item
Play the role of tender skin by adding some chemical components or bioactive ingredients in skin care item, such as various lotions,
Skin cream, facial mask etc..But skin care item, there is also very big defect, individual difference is obvious, may have the opposite effect, allergy is very
To disfeaturing；Heavy metals exceeding standard；Various nocuousness additives: such as hormone, preservative, pigment.The various adverse reactions of skin care item and danger
Evil has been obvious to all.And tender skin effect is difficult to persistently, and horse back skin quality is deteriorated after deactivating.
2. tender skin class health food
Various vitamins, various collagens, the health care product of tender skin class developed it is multifarious, it is dazzling.However, protecting
The formula of health food is indefinite, and businessman may inside add some harmful chemical components；Health care product is long-term or excessive use
It will cause other body injuries.
3. functional food
Due to skin care item, health care product is harmful, and function then occur is food.Honey amino acid rich in, vitamin,
So that skin is ruddy glossy；Nut is rich in vitamin e, anti-oxidant；Agaric vitamin rich in and minerals can delay
Solve skin melanin deposition, improve the coarse situation of skin etc..Common food does not obviously endanger, and has effect to tender skin.But
Active constituent content in common food is small, and to there is apparent skin quality improvement, daily intake is inadequate, it is necessary to
Super amount long-term takes, this is easy for causing the unbalanced of nutrition, the harm such as anorexia.
4. Novel medical beautifying technique
In recent years, with the development of science and technology, there are some novel facial beautification and skin rejuvenation function technologies, as photon delicate skin, glory are tender
Skin, laser whitening and softening skin etc..They be all by using the intense pulsed light skin of various different wave frequencies, promote skin at distribution
Changing, if active principle converts, pigment is decomposed.This kind of technology takes effect significantly, quick.But what is also had very important lacks
Point: different wavelength can be easy pigment and deepened or the problem of pigment bleaches by different skin pigment absorptions；It is easy because of energy
Too strong burned skin is measured, has certain destruction to skin, keeps skin keratin thinning；It is easy to influence normally perspiring for skin pore
Function etc.
With the development of society, huge development potentiality and the market demand that tender skin product, technology have.However tender skin class of today
There is various problems for product, technology.Therefore developing a kind of has positive effect, tender skin safe, without side-effects to produce on tender skin
Product, technology are necessary.
Summary of the invention
Some is not used to improve the substance (rubber tree of skin skin quality the purpose of the present invention is to provide a kind of in the prior art
The unsaponifiable matter of seed fatty contents) and its application.The substance is the unsaponifiable matter of the fatty contents of the seed of rubber tree,
It can be applied to health food, food, in cosmetics, for improving the skin quality of skin.The object is added to by edible or smearing
Health food, food, the cosmetics of matter can be obtained good tender skin effect.
In order to realize above-mentioned purpose of the invention, the present invention provides the following technical solutions:
The unsaponifiable matter of seeds of rubber tree fatty contents, the unsaponifiable matter of the seeds of rubber tree fatty contents is by following methods
It is prepared:
Using virgin rubber tree species as raw material, after drying shelling, kernel is prepared, kernel passes through mechanical presses method, extraction
The lipoclastic of seeds of rubber tree is made in one or more of method, supercritical extraction, is original with the lipoclastic of seeds of rubber tree
Material is added excessive potassium hydroxide-ethanol solution and carries out saponification, after saponification terminates, under vacuum conditions, heating
Ethyl alcohol is recycled, one of unsaponifiable matter extractant ether, ethyl acetate, n-hexane, No. 6 solvents are added later and is extracted,
Upper layer of extraction liquid is isolated, under vacuum conditions reheating, recycle extractant, remaining liquid is seeds of rubber tree
The unsaponifiable matter of fatty contents.
Invention also provides the unsaponifiable matter containing the seeds of rubber tree fatty contents and health food are normal
The health food formed with carrier.
And food, it is made of the unsaponifiable matter and food common carrier of the seeds of rubber tree fatty contents.
With cosmetics, by the unsaponifiable matter and cosmetics common carrier institute group of the seeds of rubber tree fatty contents
At.
The present invention also provides the unsaponifiable matter of the seeds of rubber tree fatty contents in the health care for improving skin skin quality
Application in food.
Application as mentioned, wherein the seeds of rubber tree fatty contents are as sole active agent.
Present invention further provides the unsaponifiable matter of the seeds of rubber tree fatty contents to improve skin skin quality
Food in application.
And the unsaponifiable matter of the seeds of rubber tree fatty contents is in the cosmetics product for improving skin skin quality
Using.
Application as mentioned, wherein the unsaponifiable matter of the seeds of rubber tree fatty contents as sole active at
Point.
Compared with the existing health food for improving skin skin quality, food, cosmetics, the present invention has the advantage that
1. providing a kind of completely new substance to improve skin skin quality；
2. it is direct-edible, it is also used as skin care item smearing；
3. as may act on Whole Body skin after eating, and being not limited solely to part；
4. having no toxic side effect, it can be eaten for a long time or use.
Specific embodiment
Below by the embodiment of the present invention, property content is described further for the essence of the present invention, but is not limited with this
The fixed present invention.
Embodiment 1
SPF grades of healthy test mices 144, half male and half female, weight are 25 ± 2g.Test mice is divided into 6 groups, every group of male and female are each
12.Take wherein one group be blank group, normal to feed, the seeds of rubber tree that A, B group add various dose in food is fat-soluble
The unsaponifiable matter of substance, C group add the unsaponifiable matter of purple perilla seed liposoluble substance in food, and D group adds olive in food
The unsaponifiable matter of liposoluble substance, E group add the unsaponifiable matter of sunflower seeds liposoluble substance in food.Daily additive amount is such as
Under:
1 experimental group of table and additive amount situation
| Experimental group | Blank group | A | B | C | D | E |
| Additive amount | It does not add | 0.0625g | 0.375g | 0.375g | 0.375g | 0.375g |
By 1 additive amount of table, after feeding 60 days, the sample and apparent outliers of unusual death in removal experiment, remaining
It puts to death, every mouse takes the skin of same area, measures the content of hydroxyproline and collagen in skin respectively.As a result as follows:
2 each group hydroxyproline of table, collagen content
| Group | Valid data Quantity | Hydroxyproline content (mg/g) | Collagen content (mg/g) | Opposite blank pair According to group | Substance height of the present invention Dosage group |
| Blank group | 20 | 36.2±5.3 | 261.1±6.1 | ------ | ------ |
| Test A group | 20 | 52.0±7.1 | 348.3±5.7 | P<0.01 | ------ |
| Test B group | 20 | 57.4±5.2 | 373.8±6.4 | P<0.01 | P<0.05 |
| Test C group | 20 | 42.3±5.5 | 282.1±5.9 | P>0.05 | ------ |
| Test D group | 20 | 40.5±5.7 | 280.7±4.5 | P>0.05 | ------ |
| Test E group | 20 | 38.2±6.6 | 277.5±5.0 | P>0.05 | ------ |
As seen from the results in Table 2, after mouse has eaten the food of the unsaponifiable matter of addition seeds of rubber tree liposoluble substance, in skin
Hydroxyproline and collagen dramatically increase, and incrementss are positively correlated with additive amount.And in an experiment it has also been found that feeding
The mouse fur for adding the food of the unsaponifiable matter of seeds of rubber tree liposoluble substance is more smooth, submissiveer than blank group.
Test result is also shown that the unsaponifiable matter of edible purple perilla seed liposoluble substance, olive liposoluble substance are not saponified
The unsaponifiable matter of object and sunflower seeds liposoluble substance has an impact to the content of hydroxyproline and collagen in mouse skin but not
Significantly.
Embodiment 2
SPF grades of healthy test mices 144, half male and half female, weight are 25 ± 2g.Test mice is divided into 6 groups, every group of male and female are each
12.Take wherein one group be blank group, it is normal to feed.Remaining group smears different material in the same area skin of mouse: A, B group applies
The unsaponifiable matter of different amounts of seeds of rubber tree liposoluble substance is smeared, C group smears the unsaponifiable matter of purple perilla seed liposoluble substance, D
Group smears the unsaponifiable matter of olive liposoluble substance, and E group smears the unsaponifiable matter of sunflower seeds liposoluble substance.Daily applying amount is such as
Under:
The grouping of table 3 and applying amount situation
| Experimental group | Blank group | A | B | C | D | E |
| Applying amount | It does not smear | 0.0625g | 0.375g | 0.375g | 0.375g | 0.375g |
By the applying amount of table 3, after smearing 60 days, the sample and apparent outliers of unusual death in removal experiment,
Remaining execution takes every mouse to smear the skin at position, measures the content of hydroxyproline and collagen in skin respectively.As a result such as
Under:
4 each group each group hydroxyproline of table, collagen content
| Group | Valid data Quantity | Hydroxyproline content (mg/g) | Collagen content (mg/g) | Opposite blank pair According to group | Substance height of the present invention Dosage group |
| Blank group | 20 | 38.3±5.0 | 265.1±6.2 | ------ | ------ |
| Test A group | 20 | 53.7±6.4 | 352.3±4.9 | P<0.01 | ------ |
| Test B group | 20 | 58.8±5.7 | 377.7±5.9 | P<0.01 | P<0.05 |
| Test C group | 20 | 41.5±6.3 | 282.1±6.5 | P>0.05 | ------ |
| Test D group | 20 | 40.7±5.8 | 280.9±4.8 | P>0.05 | ------ |
| Test E group | 20 | 39.0±4.4 | 267.1±5.0 | P>0.05 | ------ |
As shown in Table 4, after the unsaponifiable matter of mouse smearing seeds of rubber tree liposoluble substance, hydroxyproline and collagen egg in skin
It is white to dramatically increase, and incrementss are positively correlated with applying amount.
Test result is also shown that the unsaponifiable matter for smearing sunflower seeds liposoluble substance to hydroxyproline in mouse skin and glue
The content of former albumen has no significant effect, and smears the unsaponifiable matter of olive liposoluble substance and the not soap of purple perilla seed liposoluble substance
Compound has an impact to the content of hydroxyproline in mouse skin and collagen but not significant.
Embodiment 3
Using 100kg virgin rubber tree species as raw material, after drying shelling, kernel 40kg is prepared.Kernel material arrives 80- in heat
100 DEG C, then by static extruding, pressure 50MPa, squeezing out 13kg liquid is substance rubber tree species of the invention
Sub- fatty contents.
Using the lipoclastic of 10kg seeds of rubber tree as raw material, 10kg potassium hydroxide-ethanol solution is added and carries out saponification,
The mass percent concentration of potassium hydroxide in ethanol is 22%.After saponification terminates, under 0.01atm vacuum condition, heating
To 120 DEG C of recycling ethyl alcohol；5kg ether is added later to extract as unsaponifiable matter extractant, isolates upper layer of extraction liquid,
Under 0.01atm vacuum condition, 85 DEG C of recycling extractants are heated to, 400g liquid, rubber tree species as of the invention are obtained
The unsaponifiable matter of the fatty contents of son.
Two women first, second, age are 39 years old, and two people have dry skin, is coarse, relaxation is nonelastic.Usually in life
Two people eat the skin-tendering health-care product skin care of certain brand.Skin is tested with skinanalysis apparatus.
5 first and second liang of people of table eat the skin conditions before substance of the present invention
| Test object | Moisture | Reference value | Oil | Reference value | Coefficient of elasticity | Reference value |
| First | 25.2% | 40-60% | 10.8% | 15-23% | 0.29 | 0.45-0.55 |
| Second | 27.1% | 40-60% | 11.5% | 15-23% | 0.28 | 0.45-0.55 |
After test, first deactivates the skin-tendering health-care product of certain brand, only eats seeds of rubber tree liposoluble substance system disclosed by the invention
At health food, amount be 5 grams/day (by for improve skin skin quality substance in terms of).After 90 days edible, feel that skin has
It is obviously improved, becomes water and moisten, is flexible.It is surveyed with the Fiss Kai Er skin composite index measuring instrument of Kai Er Electronic Instruments Plant, Shenzhen
Try skin, moisture: 48.8%；Oil: 18.6%；Coefficient of elasticity: 0.50.
Second deactivates the skin-tendering health-care product of certain brand, starts the unsaponifiable matter of the edible liposoluble substance extracted from purple perilla seed
Manufactured food, amount are 5 grams/day (in terms of the unsaponifiable matter from the liposoluble substance extracted in purple perilla seed).After 3 months,
The skin skin quality of second improves unobvious.It is tested with the Fiss Kai Er skin composite index measuring instrument of Kai Er Electronic Instruments Plant, Shenzhen
Skin, moisture: 30.5%；Oil: 15.6%；Coefficient of elasticity: 0.33.
Embodiment 4
Using 100kg virgin rubber tree species as raw material, after drying shelling, kernel 40kg is prepared.Kernel material arrives 80- in heat
100 DEG C, then pass through dynamic screw extrusion, the screw extrusion time is 45 seconds or so, and squeezing out 14kg liquid is this hair
Bright substance seeds of rubber tree fatty contents.
Using the lipoclastic of 10kg seeds of rubber tree as raw material, 10kg potassium hydroxide-ethanol solution is added and carries out saponification,
The mass percent concentration of potassium hydroxide in ethanol is 22%.After saponification terminates, under 0.005atm vacuum condition, add
Heat is to 120 DEG C of recycling ethyl alcohol；5kg ethyl acetate is added later to extract as unsaponifiable matter extractant, isolates upper layer of extraction liquid,
Under 0.01atm vacuum condition, 120 DEG C of recycling extractants are heated to, it is of the invention for obtaining the remaining liquid of 430g
The unsaponifiable matter of the fatty contents of seeds of rubber tree.
Two women first, second, age are 40 years old, and the equal skin greasing of two people, dimness, relaxation is nonelastic.Usually in life
Two people eat identical tender skin food and carry out skin care.Skin is tested with skinanalysis apparatus.
6 first and second liang of people of table eat the skin conditions before substance of the present invention
| Test object | Moisture | Reference value | Oil | Reference value | Coefficient of elasticity | Reference value |
| First | 35.3% | 40-60% | 25.6% | 15-23% | 0.31 | 0.45-0.55 |
| Second | 36.2% | 40-60% | 25.1% | 15-23% | 0.32 | 0.45-0.55 |
After test, first stopping eats tender skin food, only eats food made of seeds of rubber tree liposoluble substance disclosed by the invention
Product, amount are 15 grams/day (in terms of for the substance for improving skin skin quality).After 3 months edible, feel that skin has and obviously change
It is kind, become to moisten white, flexible.Skin is tested with the Fiss Kai Er skin composite index measuring instrument of Kai Er Electronic Instruments Plant, Shenzhen
Skin, moisture: 50.5%；Oil: 16.8%；Coefficient of elasticity: 0.49.
Second stopping eats tender skin food, starts food made of the unsaponifiable matter of the edible liposoluble substance extracted from olive
Product, amount are 15 grams/day (in terms of the unsaponifiable matter from the liposoluble substance extracted in olive).After 3 months, the skin skin of second
Matter improves unobvious.Skin is tested with the Fiss Kai Er skin composite index measuring instrument of Kai Er Electronic Instruments Plant, Shenzhen, moisture:
40.5%；Oil: 23.5%；Coefficient of elasticity: 0.37.
Embodiment 5
Using 100kg virgin rubber tree species as raw material, after drying shelling, kernel 40kg is prepared.Then kernel is subjected to extruding
After processing, it is put into the leaching container of sealing, the solvent of 2 times of weight is added.In 55 DEG C of (being lower than solvent boiling point) conditions and normal pressure
Under, material is stirred and is mixed with solvent, material is allowed to come into full contact with solvent.It staticly settles later, leaches solvent, then
120 DEG C (being higher than solvent boiling point temperature) under 100Pa vacuum condition, solvent is allowed to volatilize, staying 19kg liquid is
Substance seeds of rubber tree fatty contents of the invention.
Using the lipoclastic of 10kg seeds of rubber tree as raw material, 10kg potassium hydroxide-ethanol solution is added and carries out saponification,
The mass percent concentration of potassium hydroxide in ethanol is 22%.After saponification terminates, under 0.005atm vacuum condition, add
Heat is to 120 DEG C of recycling ethyl alcohol；N-hexane is added later to extract as unsaponifiable matter extractant, isolates upper layer of extraction liquid,
Under 0.005atm vacuum condition, 120 DEG C of recycling extractants are heated to, obtaining 450g liquid is rubber tree species of the invention
The unsaponifiable matter of the fatty contents of son.
Two women first, second, age are 43 years old, and two people have dry skin, relaxation is nonelastic.Usually two people are equal in life
With identical skin care item skin care.Skin is tested with skinanalysis apparatus.
7 first and second liang of people of table use the skin conditions before substance of the present invention
| Test object | Moisture | Reference value | Oil | Reference value | Coefficient of elasticity | Reference value |
| First | 25.4% | 40-60% | 11.7% | 15-23% | 0.28 | 0.45-0.55 |
| Second | 24.8% | 40-60% | 10.6% | 15-23% | 0.27 | 0.45-0.55 |
After test, first stops using other skin care item, only uses the not soap of seeds of rubber tree liposoluble substance disclosed by the invention
Cosmetics made of compound, usage amount are 30 grams/day (in terms of for the substance for improving skin skin quality).After 3 months, feel
Skin has clear improvement, and becomes water and moistens, is flexible.It is surveyed with the Fiss Kai Er skin composite index of Kai Er Electronic Instruments Plant, Shenzhen
It measures instrument and tests skin, moisture: 47.5%；Oil: 17.7%；Coefficient of elasticity: 0.46.
Second stops using original skin care item, begins to use the unsaponifiable matter system of the liposoluble substance extracted from sunflower seeds
At cosmetics, usage amount be 30 grams/day (in terms of the unsaponifiable matter from the liposoluble substance extracted in sunflower seeds).After 3 months,
The skin skin quality of second improves unobvious.It is tested with the Fiss Kai Er skin composite index measuring instrument of Kai Er Electronic Instruments Plant, Shenzhen
Skin, moisture: 28.3%；Oil: 23.5%；Coefficient of elasticity: 0.31.
Embodiment 6
The unsaponifiable matter of seeds of rubber tree fatty contents of the invention is made by the method in embodiment 3-5, by the part with
Excipient, pelletizing press sheet is added in the ratio of excipient weight ratio 1:1 or 1:2.Tablet can be used as health food or food.
Embodiment 7:
The unsaponifiable matter of seeds of rubber tree fatty contents of the invention is made by the method in embodiment 3-5, the part is taken to wrap
It is rolled in soft capsule material, routinely soft capsule is made in capsule preparations method.Soft capsule can be used as health food or food.
Embodiment 8:
The unsaponifiable matter of seeds of rubber tree fatty contents of the invention is made by the method in embodiment 3-5, takes the part, adds
Upper emulsifier, osmotic pressure regulator and water obtain emulsion for injection by high-pressure homogeneous emulsification.
Embodiment 9:
The unsaponifiable matter of seeds of rubber tree fatty contents of the invention is made by the method in embodiment 3-5, takes the part, then
Tablet is made as follows:
Tablet: the unsaponifiable matter 100mg of seeds of rubber tree fatty contents
Appropriate starch
Appropriate corn pulp
Magnesium Stearate proper quantity
Preparation method: the unsaponifiable matter of seeds of rubber tree fatty contents is mixed with auxiliary agent, sieving, in suitable container
Even mixing, obtained granulating mixture tabletting.
Embodiment 10:
The unsaponifiable matter of seeds of rubber tree fatty contents of the invention is made by the method in embodiment 3-5, takes the part, then
Soft capsule is made as follows:
Soft capsule: the unsaponifiable matter 1000mg of seeds of rubber tree fatty contents
Appropriate gelatin
Appropriate glycerol
Appropriate amount of water
Preparation method: gelatin, glycerol, which are put into distilled water, to impregnate makes gelatin expansion, softening, is then uniformly mixed, obtains
Capsule material glue.Prepared capsule material glue is taken out, is coated in flat plate surface, keeps thickness uniform, then with 90 DEG C or so
Temperature heating, evaporates surface moisture, becomes the cushion compound for having certain toughness, having certain elasticity.Finally with pelleting mold or
Automatic rotation rolling capsule machine, the unsaponifiable matter (1000mg) of seeds of rubber tree fatty contents is fitted into soft capsule skin, is produced
Soft capsule.
Embodiment 11:
The unsaponifiable matter of seeds of rubber tree fatty contents of the invention is made by the method in embodiment 3-5, takes the part, then
Milky lotion is made as follows:
Milky lotion: the unsaponifiable matter 300g of seeds of rubber tree fatty contents
Appropriate emulsifier
Appropriate glycerol
Appropriate hydrosol
Preservative qs
Preparation method: according to formula, by the unsaponifiable matter of seeds of rubber tree fatty contents, emulsifier, glycerol heating mixing adds
Appropriate hydrosol and preservative, mix, and are down to room temperature to get milky lotion is arrived.
Embodiment 12:
Tablet: the unsaponifiable matter 10mg of seeds of rubber tree fatty contents of the invention being made by the method in embodiment 3-5, cream
Sugared 180mg, starch 55mg, magnesium stearate 5mg；
Preparation method: by be made by the method in embodiment 3-5 seeds of rubber tree fatty contents of the invention unsaponifiable matter,
Newborn sugar and starch mixing, is uniformly moistened with water, and the mixture after moistening is sieved and is dried, re-sieving, magnesium stearate is added, so
Afterwards by mixture tabletting, every slice weight 250mg, the unsaponifiable matter content of seeds of rubber tree fatty contents of the invention is 10mg.
Embodiment 13:
Capsule: the unsaponifiable matter of seeds of rubber tree fatty contents of the invention is made by the method in embodiment 3-5
2000g, gelatin 1000g, glycerol 500g, water 1000g；
Preparation method: by gelatin 1000g, glycerol 500g, being put into 1000g water to impregnate makes gelatin expansion, softening, and then stirring is mixed
It closes uniformly, obtains capsule material glue.Prepared capsule material glue is taken out, is coated in flat plate surface, keeps thickness uniform, then uses
90 DEG C or so of temperature heating, evaporates surface moisture, becomes the cushion compound for having certain toughness, having certain elasticity.Finally with pressure
Ball mold rotates rolling capsule machine automatically, and the unsaponifiable matter 1000mg of seeds of rubber tree fatty contents is packed into soft capsule skin
In, soft capsule is made.Every soft capsule weight 1.4g, the unsaponifiable matter content of seeds of rubber tree fatty contents of the invention are
1000mg。
Embodiment 14:
Milky lotion: the unsaponifiable matter 300g of seeds of rubber tree fatty contents of the invention being made by the method in embodiment 3-5,
Emulsifier 80g, glycerol 70g, hydrosol 445g, preservative 5g,.
Preparation method: seeds of rubber tree fatty contents of the invention are made not by the method in embodiment 3-5 in accurate weighing
Saponified 300g, emulsifier 80g, glycerol 75g, mixing, are heated to 70-80 DEG C, mix.Hydrosol 445g(is added to be heated in advance
70-80 DEG C) and preservative 5g, it mixes, is cooled to room temperature.It is filled in the vial of 250mL and encapsulates.
Embodiment 15:
Food: the unsaponifiable matter of seeds of rubber tree fatty contents of the invention is made by the method in embodiment 3-5, by the portion
Divide and reconciled with oil with common edible, is directly becoming food (edible oil).
Preparation method: seeds of rubber tree fatty contents of the invention are made not by the method in embodiment 3-5 in 10kg
It is saponified, it is added in 10kg soybean oil, obtains 20kg blending edible oil.By the filling vial at 500g of blending edible oil,
The unsaponifiable matter content of seeds of rubber tree fatty contents of the invention is 250g.
Claims (10)
1. the unsaponifiable matter of the fatty contents of seeds of rubber tree, it is characterised in that the fatty contents of the seeds of rubber tree are not
It is saponified to be prepared by following methods kind:
Using virgin rubber tree species as raw material, after drying shelling, kernel is prepared, kernel passes through mechanical presses method, extraction
The lipoclastic of seeds of rubber tree is made in one or more of method, supercritical extraction, then with the lipoclastic of seeds of rubber tree
For raw material, excessive potassium hydroxide-ethanol solution is added and carries out saponification, after saponification terminates, under vacuum conditions,
Heating recovery ethyl alcohol, later be added unsaponifiable matter extractant extracted, selected extractant be ether, ethyl acetate, n-hexane,
One of No. 6 solvents isolate upper layer of extraction liquid, under vacuum conditions reheating, recycle extractant, remaining liquid object
Matter is the unsaponifiable matter of the fatty contents of seeds of rubber tree.
2. health food is commonly used by the unsaponifiable matter and health food of seeds of rubber tree fatty contents described in claim 1
Carrier is formed.
3. food, by the unsaponifiable matter and food common carrier institute group of seeds of rubber tree fatty contents described in claim 1
At.
4. cosmetics, by the unsaponifiable matter and cosmetics common carrier of seeds of rubber tree fatty contents described in claim 1
It is formed.
5. the unsaponifiable matter of seeds of rubber tree fatty contents described in claim 1 is in the health food that preparation improves skin quality
Application.
6. application as claimed in claim 5, which is characterized in that the unsaponifiable matter of the seeds of rubber tree fatty contents
As sole active agent.
7. the unsaponifiable matter of seeds of rubber tree fatty contents described in claim 1 answering in the food that preparation improves skin quality
With.
8. application as claimed in claim 7, which is characterized in that the unsaponifiable matter of the seeds of rubber tree fatty contents
As sole active agent.
9. the unsaponifiable matter of seeds of rubber tree fatty contents described in claim 1 is in the cosmetics for improving skin skin quality
Using.
10. application as claimed in claim 9, which is characterized in that the seeds of rubber tree fatty contents are not saponified
Object is as the sole active agent in cosmetics.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711140043.XA CN109793224A (en) | 2017-11-16 | 2017-11-16 | It is a kind of for improving the preparation and its application of the substance of skin skin quality |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711140043.XA CN109793224A (en) | 2017-11-16 | 2017-11-16 | It is a kind of for improving the preparation and its application of the substance of skin skin quality |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109793224A true CN109793224A (en) | 2019-05-24 |
Family
ID=66555704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711140043.XA Withdrawn CN109793224A (en) | 2017-11-16 | 2017-11-16 | It is a kind of for improving the preparation and its application of the substance of skin skin quality |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109793224A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1215059A (en) * | 1997-10-18 | 1999-04-28 | 李世泰 | Extration of steroid compound from rubber seeds |
| CN101288358A (en) * | 2007-04-16 | 2008-10-22 | 中国热带农业科学院热带生物技术研究所 | Rubber seed storage technique |
-
2017
- 2017-11-16 CN CN201711140043.XA patent/CN109793224A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1215059A (en) * | 1997-10-18 | 1999-04-28 | 李世泰 | Extration of steroid compound from rubber seeds |
| CN101288358A (en) * | 2007-04-16 | 2008-10-22 | 中国热带农业科学院热带生物技术研究所 | Rubber seed storage technique |
Non-Patent Citations (2)
| Title |
|---|
| 吴英艳: "植物甾醇的提取研究", 《中国优秀硕士学论文全文数据库工程科技Ι辑》 * |
| 王慧敏: "橡胶籽油的提取、精炼及其氧化稳定性研究", 《中国优秀硕士学论文全文数据库工程科技Ι辑》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105748343B (en) | A kind of natural plant extracts composition and its application in cosmetics | |
| CN106214529A (en) | A kind of food stage hand cream | |
| CN105919906A (en) | Beauty and health care composition | |
| CN105362150A (en) | Hair conditioner | |
| CN108348441A (en) | The lip for containing natural ceramide and rose hip oil as active ingredient protects the composition that applies some make up | |
| CN105394749A (en) | Formula, preparation method and application of astaxanthin-containing health food | |
| CN106722444A (en) | A kind of preparation method of sea-buckthorn chewing tablet | |
| CN109793224A (en) | It is a kind of for improving the preparation and its application of the substance of skin skin quality | |
| CN108653124A (en) | It is a kind of repair damaged skin composition and its application | |
| CN107674789A (en) | A kind of cold process soap with skin-active effect and preparation method thereof | |
| CN109793679A (en) | It is a kind of for improving the preparation and its application of the substance of skin skin quality | |
| CN109793220A (en) | It is a kind of for improving the preparation and its application of the substance of skin skin quality | |
| CN104168906B (en) | American Avocado Tree is used to obtain the purposes in the avocado unsaponifiable matter object rich in saturated aliphatic hydrocarbon and sterol | |
| CN105614861B (en) | Golden flower fibert chewable tablets and preparation method thereof | |
| CN101708173B (en) | Soft capsule and application thereof | |
| CN106539699A (en) | A kind of sericin protective skin cream with pox-eliminating whitening effect and preparation method thereof | |
| CN105686005A (en) | Collagen preparation and production method thereof | |
| KR20190024043A (en) | Chocolate lipstick produced 3D printer | |
| CN100404044C (en) | Chloasma diminishing medicine containing deer foetus and functional food and preparing method | |
| CN108294975A (en) | A kind of alligator oil maintenance composition and its application | |
| CN1293907C (en) | Health article for improving skin water content and preparing method | |
| CN109222111A (en) | A kind of food compositions with beautification function | |
| CN110115382A (en) | A kind of bright soft capsule of benefit that can alleviate visual fatigue and its production method | |
| CN107184574A (en) | A kind of compound vitamin E soft capsule and preparation method thereof | |
| CN107050166A (en) | It is a kind of to treat natural biology degradation element of immunity disease and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20190524 |