CN109789301B - Needle plate seal - Google Patents

Needle plate seal Download PDF

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Publication number
CN109789301B
CN109789301B CN201780052430.XA CN201780052430A CN109789301B CN 109789301 B CN109789301 B CN 109789301B CN 201780052430 A CN201780052430 A CN 201780052430A CN 109789301 B CN109789301 B CN 109789301B
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needle
chamber
drug delivery
stamp
needle plate
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CN109789301A (en
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李昌雨
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

According to an aspect of the present invention, there is provided a needle plate stamp for use in conjunction with a vial containing a liquid drug. The needle plate stamp includes: a viscoelastic coupler detachably connected to the front end opening of the medicine bottle and internally formed with a medicine bottle connecting chamber; a stamp cover including a coupler connection part connected with the viscoelastic coupler and a needle tip guide part communicated with the coupler connection part in front of the coupler connection part, and having a drug transfer chamber formed therein; a needle tip including a tip cover linearly sliding along the needle tip guide and a plurality of non-rotating needle plates disposed in the tip cover, the non-rotating needle plates having a plurality of needles formed in front thereof to be in contact with external skin and a plurality of rear protrusions formed in rear thereof to be received in the drug delivery chamber; and a drug delivery mechanism that closes the space between the vial connection chamber and the drug delivery chamber in a state where the needle tip advances, and opens a drug delivery path between the vial connection chamber and the drug delivery chamber if the needle tip retreats.

Description

Needle plate seal
Technical Field
The present invention relates to a pin plate stamp in which a minute hole is formed in the skin by a non-rotating pin plate and a medicine is injected through the minute hole.
Background
Dial roller arrangements are proposed in the prior art. The dial roller device is detachably coupled to a medicine bottle storing a liquid medicine and having a neck with a certain inner diameter, and includes: a connecting cap detachably coupled to the medicine bottle; a roller guide fixer combined on the upper end of the connecting cover; the needle dial roller is held by a roller guide holder so as to be linearly movable. The dial roller has a plurality of rotating type dials which are pressed to form minute holes while the skin is rotated. Drugs can then be injected into the skin through such tiny holes. However, the conventional dial roller device is complicated in structure and requires many parts, thereby being low in cost performance. In addition, the dial contacting the skin scratches the skin while rotating, and thus an accurate manufacturing process is required. In contrast, a needle stamp in which a plate formed with a plurality of needles presses the skin and presses the skin has been proposed in the related art. However, the conventional needle stamp is used by separately manufacturing a plurality of needles to be combined with a plate, and thus has low cost performance and many structural limitations in providing functions to the skin such as medicines.
Disclosure of Invention
(problem to be solved)
The invention aims to solve the problem of providing the following needle plate stamp: the non-rotating needle plate has a drug delivery chamber communicating with the interior of the drug vial when pressed against the skin, and the rearward end of the non-rotating needle plate enters the drug delivery chamber so that the drug from the drug delivery chamber is transferable along the surface of the needle plate to the needles of the needle plate.
(means for solving the problems)
According to an aspect of the present invention, there is provided a needle plate stamp for use with a medicine bottle containing a medicine in a liquid state, the needle plate stamp including: a viscoelastic coupler detachably connected to the front end opening of the medicine bottle and internally formed with a medicine bottle connecting chamber; a stamp cover including a coupler connection part connected with the viscoelastic coupler and a needle tip guide part communicated with the coupler connection part in front of the coupler connection part, and having a drug transfer chamber formed therein; a needle tip including a tip cover sliding along the needle tip guide and a plurality of non-rotating needle plates disposed inside the tip cover, a plurality of needles contactable to external skin being formed in front of the non-rotating needle plates, and a plurality of rear protrusions received in the drug delivery chamber being formed in rear of the non-rotating needle plates; and a drug delivery mechanism that closes the space between the vial connection chamber and the drug delivery chamber in a state where the needle tip advances, and opens a drug delivery path between the vial connection chamber and the drug delivery chamber if the needle tip retreats.
According to an embodiment, the pin plate stamp further comprises: the stamp core is connected with the needle point at the front end; a viscoelastic membrane disposed between the viscoelastic coupler and the drug delivery chamber; wherein the stamp core comprises: a rod part and a tapered pressing part which is formed at the front end of the rod part and gradually increases the outer diameter as going forward; the drug delivery mechanism includes: and a valve hole formed in the center of the viscoelastic film to be inserted into the rod part, and a valve groove formed in the tapered pressurizing part to be connected to the valve hole and open the space between the drug delivery chamber and the vial connection chamber when the tapered pressurizing part is retracted to expand the valve hole.
According to an embodiment, the pin plate stamp further comprises: the stamp core is connected with the needle point at the front end; wherein the stamp core comprises: a support plate portion supporting the plurality of non-rotating needle plates; and a connecting plate portion that forms a right angle with the support plate portion at a front end portion of the support plate portion and is assembled to the pointed cover, and the pointed cover includes: a sliding cylinder part which is inserted into the inner side surface of the needle point guide part in a sliding way in the medicine transfer chamber and can move forwards to a position contacting with a stopper at the front end of the needle point guide part; and a tip cap front surface portion covering a hollow front end of the slide cylinder portion, and the tip cap front surface portion includes: a plurality of first faller bar slots which accommodate a forward portion of each of the plurality of non-rotating faller bars; and a plurality of needle passing holes respectively connected with the first needle plate slits and passed one by a plurality of needles of the non-rotating needle plate, and the connecting plate portion includes: second needle plate slits formed in matching relation with the first needle plate slits and accommodating rear portions of the non-rotating needle plates; and a plurality of protrusion passing holes connected to the second needle plate slits and passed one by the plurality of rear protrusions of the non-rotating needle plate until the medicine delivery chamber.
According to an embodiment, the first needle plate slit and the second needle plate slit form a maximum width at a boundary position where they meet each other, and the width is gradually narrowed as being farther from the boundary position, the needle passage hole forming width is smaller than a minimum width of the first needle plate slit, and the projection passage hole forming width is smaller than a minimum width of the second needle plate slit.
According to an embodiment, the support plate portion has a width gradually increasing to extend to an inner side of the needlepoint guide portion and allows the medicine to flow to both sides of a thickness portion thereof, the connection plate portion has a shape and a size blocking a flow path of the medicine transfer chamber in a region outside the plurality of second needle plate slits, and the connection plate portion includes a plurality of assembling protrusions fitted into a plurality of assembling grooves formed at front portions of the plurality of needlepoint covers.
(Effect of the invention)
According to the invention, the following needle plate stamp is realized: when the non-rotating needle plate is pressed by the skin, a drug delivery chamber is provided which communicates with the interior of the drug vial, and the rear end of the non-rotating needle plate enters the drug delivery chamber so that the drug of the drug delivery chamber is transferable along the surface of the needle plate to the needles of the needle plate.
Other advantages and effects of the present invention will be understood from the following description of the embodiments.
Drawings
Fig. 1 is a photograph showing a pin plate stamp according to an embodiment of the present invention.
Fig. 2 is a longitudinal sectional view showing a needle plate stamp according to an embodiment of the present invention, and a first longitudinal section can be seen.
Fig. 3 is a longitudinal sectional view showing a needle plate stamp according to an embodiment of the present invention, and a second longitudinal section which crosses at right angles to the first longitudinal section can be seen.
Fig. 4 is a drawing for explaining a tip cover of a needle plate stamp according to an embodiment of the present invention.
Fig. 5 is a drawing for explaining a connecting plate portion of a needle plate stamp according to an embodiment of the present invention.
Detailed description of the invention
Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. The drawings and the description related thereto are provided to assist those having ordinary knowledge in the art in understanding the intent of the present invention. Therefore, the drawings and the description are not to be construed as limiting the scope of the present invention.
FIG. 1 is a photograph showing a pin plate stamp according to an embodiment of the present invention; FIG. 2 is a longitudinal cross-sectional view showing a pin plate stamp according to an embodiment of the invention and showing a first longitudinal section; FIG. 3 is a longitudinal cross-sectional view showing a pin plate stamp according to an embodiment of the present invention, and a second longitudinal section orthogonal to the first longitudinal section can be seen; FIG. 4 is a drawing for explaining a tip cover of a pin plate stamp according to an embodiment of the present invention; fig. 5 is a drawing for explaining a connecting plate portion of a needle plate stamp according to an embodiment of the present invention.
As shown in fig. 1 to 5, a needle plate stamp 1 according to an embodiment of the present invention is used by being coupled to a distal end side opening of a vial 2 containing a liquid medicine. The vial 2 has an opening portion on its front end side and includes a vertical neck 2b having a constant inner diameter. An annular block 2a projecting radially outward is formed at the front end of the neck 2b, and an expanding portion 2c having an inner diameter larger than that of the neck 2b is formed at the rear end of the neck 2 b. The expanding portion 2c connects the inner surface of the neck 2b and the inside of the body of the medicine bottle 2. The medicine may be various kinds of medicines capable of contributing to a needle-punching operation for making a plurality of minute holes in the skin.
According to an embodiment of the present invention, the pin plate stamp 1 includes: viscoelastic coupler 10, stamp cover 20, stamp core 30, and needle tip 40. The stamp cover 20 includes: a rear coupler connecting portion 22 detachably connected to the viscoelastic coupler 10; a needle tip guide 24 which communicates with the coupler connecting part 22 in front of the coupler connecting part 22 and guides the needle tip 40 in front of the linear sliding motion. The viscoelastic coupler 10 includes: a viscoelastic film 18 covering the front end opening of the medicine bottle 2, and a valve hole 19 formed in the center of the viscoelastic film 18, wherein the viscoelastic film 18 separates a medicine transfer chamber C1 inside the stamp cover 20 and a medicine bottle connection chamber C2 directly connected to the medicine bottle 2.
The valve hole 19 is selectively opened and closed by the advance or retreat of the stamp core 30, and a medicine moving path between the medicine transfer chamber C1 and the vial connecting chamber C2 is opened or closed. In addition, the medicine accumulated in the medicine transfer chamber C1 is sucked by the advance of the stamp core 30, thereby discharging the medicine forward.
The viscoelastic coupler 10 is a part of the needle plate stamp 1, and can reliably assemble the needle plate stamp 1 to the vial 2 in a sealed state. In addition, the viscoelastic coupler 10 is detachably attached to the vial 2 by one-click, and is also detachably attached to the stamp cover 20.
The viscoelastic coupler 10 can improve the assembling property with the medicine bottle 2 and the assembling property with the stamp cover 20, and is formed of a silicon material made of a viscoelastic material capable of improving the elastic expansibility and contractibility of a valve hole described in detail below. In addition, the viscoelastic coupler 10 includes: a rear outer tube portion 120a having a circular inner periphery and configured to be closely attached to the outer peripheral surface of the neck 2b of the vial 2 when coupled to the distal end opening of the vial 2; a rear inner tube portion 120b inserted into the opening of the medicine bottle 2 and having a circular outer periphery closely attached to the inner peripheral surface of the neck 2b of the medicine bottle 2; a plate-shaped ring portion 120c which connects the front end inner circumference of the rear outer tube portion 120a and the front end outer circumference of the rear inner tube portion 120b and is closely attached to the front end of the bottle neck 2 b; a front outer cylinder portion 121 which is closely attached to an outer side surface of a lower end projection of the stamp cover 20 when being coupled to the lower end of the stamp cover 20; and a front inner tube section 122 coaxially formed with the front outer tube section 121 and formed inside the front outer tube section 121.
According to the present embodiment, the rear inner tube portion 120b extends rearward longer than the rear outer tube portion 120. In particular, the rear inner tubular portion 120b extends further downward past the rear end of the bottle neck 2b, and is closely attached to the rear end of the bottle neck 2b and the expanded portion 2c located below the rear end of the bottle neck 2 b. The rear inner tube portion 120b has an annular projection 129 projecting at a rear end in the annular direction. When the viscoelastic coupler is coupled to the medicine bottle 2, the annular projection 129 passes through the inside of the neck 2b of the medicine bottle 2 and is inserted after being shrunk and deformed, and covers the rear end of the neck 2b together with recovery, and is caught by the expanded portion 2c behind the neck 2b and strongly abuts against the expanded portion 2 c.
When the viscoelastic coupler 10, which is previously coupled to the stamp cap 20, is coupled to the distal end of the medicine bottle 2, the annular protrusion 129 formed in the rear inner tube portion 120b of the viscoelastic coupler 10 elastically contracts while being inserted into the bottle neck 2b, and then passes through the rear end of the bottle neck 2b and returns to the original state. If the annular projection 129 is restored to the original state, the annular projection 129 has an outer diameter larger than the inner diameter of the neck 2b, whereby the viscoelastic coupler 10 is firmly fixed to the neck of the medicine bottle 2.
The viscoelastic coupler 10 includes an annular retaining cap 121a extending inward from the front end of the front outer tube portion 121, and the annular retaining cap 121a is a part of the viscoelastic coupler 10, has viscoelasticity, elastically deforms so as to fit the rear end projection of the stamp cover 20 inward, and is in close contact with the upper surface of the rear end projection in a fitted state, thereby firmly fixing the stamp cover 20 to the viscoelastic coupler 10 in a sealed state.
As described above, the viscoelastic coupler 10 integrally includes the viscoelastic film 18, and the viscoelastic film 18 is integrally formed in the hollow inside of the front inner tube portion 122. The viscoelastic film 18 has a valve hole 19 in the center, and the valve hole 19 is allowed to be elastically expanded or contracted by an external force by the characteristics of a viscoelastic material, particularly, a silicon material.
The stamp core 30 includes: a rod 31 inserted into the valve hole 19 and extending into the vial connection chamber C2 inside the viscoelastic coupler 10; a tapered pressing portion 32 formed at a front end of the rod portion 31 and having an outer diameter gradually increasing toward the front; a support plate portion 33 extending while gradually increasing in width from the tip of the tapered pressing portion 32 to the inside of the needlepoint guide portion 24 of the stamp cover 20; and a connecting plate part 34 which forms a right angle with the supporting plate part 33 at the front end part of the supporting plate part 33 and is assembled and connected with the tip cap embedded in the tip 40. The support plate portion 33 allows the drug to flow to both sides of the thickness portion thereof.
When the stamp core 30 retreats together with the needlepoint 40, the tapered pressing portion 32 at the tip of the rod 31 retreats, and the viscoelastic film 18 of the viscoelastic coupler 10 is pressed rearward, thereby elastically supporting the stamp core 30. At this time, the drug delivery mechanism described below operates along with and together with the increase in the size of the valve hole 19. The drug delivery mechanism includes a valve groove 322, and the valve groove 322 is formed at a side of the tapered pressurizing part 32 and combined with the valve hole 19 when expanded while pushing the valve hole 19 backward.
The needlepoint 40 includes a needlepoint cover 42 and a plurality of needle plates 44, and moves forward or backward together with the stamp core 30 in a state of being provided at a front end portion of the stamp core 30. The tip cap 42 includes: a slide cylinder 422 which is accommodated in and communicates with the drug delivery chamber C1, is slidably inserted into the inner surface of the needle tip guide 24, and is advanced to a position where it contacts the stopper 242 at the front end of the needle tip guide 24; a tip cap front surface portion 424 covering the hollow front end of the slide cylinder portion 422; wherein the tip cover front surface portion 424 is formed with a plurality of first needle plate slits S1 and a plurality of needle passing holes H1, the plurality of first needle plate slits S1 accommodating front portions of the plurality of needle plates 44, respectively; the plurality of needles are connected to the respective first needle plate slits S1 through the H1 and pass through the needles 443 of the respective needle plates 44 one by one.
As described above, the connecting plate portion 34 is provided at the front end of the stamp core 30, and includes: second needle plate slits S2, which are respectively matched with the plurality of first needle plate slits S1, accommodating rear portions of the respective plurality of needle plates 44; the plurality of projections pass through the holes H2, are connected to the respective second needle plate slits S2, and pass one by the rear projections 442 of the respective needle plates 44.
The connecting plate portion 34 includes a plurality of assembling protrusions 342, and the assembling protrusions 342 are fitted into assembling grooves 4242 formed in the tip cover front surface portion 424, so that the connecting plate portion 34 is assembled to the tip cover front surface portion 424.
On the other hand, each of the plurality of dial 44 includes: a disc body portion 441; a plurality of needles 443 formed to be sharpened forward at the front end of the disk body 441; the rear protrusion 442 extends sharply rearward from the rear end of the disc main body 441. At this time, the needle plate 44, particularly the disk main body portion 441 is accommodated in the drug accumulation slits S1, S2 formed by the mutual engagement of the first needle plate slit S1 and the second needle plate slit S2. Each of the plurality of needles 443 extends forward through the needle passing hole H1 connected to the first needle plate slit S1 to a position contactable with the skin in the recessed groove 4243 of the tip cap front surface portion 424. The groove 4243 means a recessed space into which the skin pressed by the tip cover front face 424 enters.
In addition, each of the plurality of rear protrusions 442 extends to the inside of the drug delivery chamber C1 on the rear side of the web portion 34 through the protrusion passing hole H2 connected to the second needle plate slit S2.
At this time, the first needle plate slit S1 and the second needle plate slit S2 have a shape in which the maximum width is formed at a position where they meet each other and the width is gradually reduced as the distance from the boundary position increases. In addition, the needle passing holes H1 are formed to have a width smaller than the smallest width of the first needle plate slit S1, and the projection passing holes H2 are formed to have a width smaller than the smallest width of the second needle plate slit S2.
The drug accumulation slits H1, H2 formed by such mutual coupling of the first and second needle plate slits S1, S2 are shaped to accumulate a larger amount of drug. Meanwhile, the plurality of needle passing holes H1 individually pass through the plurality of needles 443 provided at the needle plate 44 in a state of being connected to the medicine accumulating slits S1, S2 accommodating one needle plate 44, and thus the medicine can be prevented from overflowing excessively. In addition, the plural projection passing holes H2 individually pass through the plural rear projections 442 provided on the needle plate 44 in a state of being connected to one medicine accumulating slit S1, S2. The medicine enters through the projection through the hole H2 and accumulates in the medicine accumulation slits S1, S2.
On the other hand, the tapered pressurizing portion 32 retreats together with the stamp core 30, and functions to open and close the valve hole 19 formed in the viscoelastic film 18. By the opening and closing operation of the valve hole 19, a medicine transfer path from the medicine bottle connection chamber C2, which is always in communication with the medicine bottle 2, to the medicine transfer chamber C1 in the stamp cover 20 is opened or closed. As described above, the drug delivery chamber C1 is defined by the space between the viscoelastic membrane 18 and the web 34, and the position of the web 34 changes along with the position of the needle tip 40, thereby also changing the volume of the drug delivery chamber C1. The connecting plate portion 34 has a region other than the region of the second needle plate slit S2, and has a shape and a size that entirely blocks the flow path of the drug delivery chamber C1. In contrast, the support plate portion 33 has a plate shape orthogonal to the connecting plate portion 34, and therefore does not block the flow path of the drug delivery chamber C1. The support plate portions 33 may act as rear projections 442 supporting a needle plate 44 which extends through the drug accumulation slots S1, S2 into the drug delivery chamber C1. Each of the rear protrusions 442 is in direct contact with the medicine in the medicine delivery chamber C1 and the rear protrusions 442 are positioned on the virtually same line in line with the needle 443, thereby more effectively delivering the medicine from each of the rear protrusions 442 to the needle 443.
According to the pin plate stamp 1 of the present embodiment, when the pin plate 44 of the needlepoint 40 is pressed by the skin and retreats, the stamp core 30 connected thereto also retreats. When the needlepoint 40 is in a non-pressurized forward state, i.e., a normal state, the medicine transfer path from the medicine bottle 2 to the needlepoint 40 side is blocked, and when the non-rotating needle plate 40 is pressurized backward by a certain distance, the medicine transfer path from the medicine bottle 2 to the non-rotating needle plate 40 side is opened. As such, a means of closing and opening the drug delivery path between the vial connection chamber C2 and the drug delivery chamber C1 by the separation and contact of the needle tip 44 from the skin, and thus the advancement and retraction of the stamp core 30, is defined as a drug delivery mechanism.
The drug delivery mechanism is as follows: when the needlepoint 40 and the stamp core 30 supporting the needlepoint 40 advance, the tapered pressurizing portion 32 blocks the valve hole 19, and thus the viscoelastic film 18 blocking the valve hole 19 blocks the transfer of the medicine between the medicine transfer chamber C1 and the vial connecting chamber C2. When the needle plate 44 is pressed by the skin to retreat the needlepoint 40 and the stamp core 30 supporting the needlepoint 40, the tapered pressurizing portion 32 retreats while expanding the valve hole 19, and the valve groove 322 of the tapered pressurizing portion 32 is connected to the valve hole 19 to open the valve hole 19. If the medicine bottle 2 is laid down below a certain inclination by the opening of the valve hole 19, the medicine in the medicine bottle 2 is transferred to the medicine transfer chamber C1 through the medicine bottle connection chamber C2. In this case, the rear end of the needle plate 44 located rearward is in contact with the medicine in the medicine transfer chamber C1 with the connecting plate 34 as a boundary, and the medicine is accumulated in the medicine accumulation slits S1 and S2 forming the connecting plate 34 and the pointed cap 42, and then the medicine is sucked forward along the side surface of the needle plate 44 with the connecting plate 34 as a reference by the forward suction action of the stamp core 30, so that the medicine can be transferred to the needle 443 of the needle plate 44.
That is, the rod 31 is fitted into the valve hole 19 formed in the viscoelastic film 18 in a sealed state without forming a fine gap, and linearly moves back and forth according to the back and forth movement of the stamp core 30 connected to the needlepoint 40. The tapered pressing portion 32 is formed at the front end of the rod portion 31 and has a tapered shape with a diameter gradually decreasing from a diameter larger than the front end of the rod portion 31 to a lower end having the same diameter as the rod portion 31. When the stamp core 30 is retracted and the viscoelastic film 18 is pressurized by the tapered pressurizing portion 32, the valve hole 19 formed in the viscoelastic film 18 expands in size corresponding to the increase in diameter of the tapered pressurizing portion 32. The valve groove 322 is formed from the outer contour of the tapered pressurization part 32 having the largest diameter to the inner side portion of the tapered pressurization part 32 having the smallest diameter, i.e., the portion meeting the rod part, so that the valve groove 322 is connected to the valve hole 19 during the expansion of the tapered pressurization part 32 into the valve hole 19, allowing the passage of the medicine from the medicine bottle connection chamber C2 to the medicine transfer chamber C1.

Claims (4)

1. A pin plate stamp for use in combination with a vial containing a liquid drug, comprising:
a viscoelastic coupler detachably connected to the front end opening of the vial and having a vial connection chamber formed therein;
a stamp cover including a coupler connection part connected with the viscoelastic coupler and a needle tip guide part communicated with the coupler connection part in front of the coupler connection part, and having a drug transfer chamber formed therein;
a needle tip including a tip cover linearly sliding along the needle tip guide and a plurality of non-rotating needle plates disposed inside the tip cover, a plurality of needles contactable with external skin being formed in front of the non-rotating needle plates, and a plurality of rear protrusions received in the drug delivery chamber being formed in rear of the non-rotating needle plates;
a drug delivery mechanism that closes a drug delivery path between the vial connection chamber and the drug delivery chamber in a state where the needle tip is advanced, and opens the drug delivery path between the vial connection chamber and the drug delivery chamber if the needle tip is retracted;
the stamp core is connected with the needle point at the front end; and
a viscoelastic membrane disposed at the viscoelastic coupler and separating the drug delivery chamber from the vial connection chamber, an
The stamp core includes: a rod part and a tapered pressing part formed at the front end of the rod part and gradually increasing the outer diameter toward the front,
the drug delivery mechanism includes: a valve hole formed in the center of the viscoelastic film to be inserted into the rod part; and a valve groove formed in the tapered pressurizing portion, the valve groove being connected to the valve hole and opening a space between the drug transfer chamber and the vial connecting chamber when the tapered pressurizing portion retracts to expand the valve hole.
2. The needle plate stamp of claim 1, further comprising: the stamp core further comprises: a support plate portion supporting the plurality of non-rotating needle plates; and a connecting plate part which forms a right angle with the supporting plate part at the front end part of the supporting plate part and is assembled on the pointed cover, and
the tip cover includes: a sliding cylinder part which is inserted into the inner side surface of the needle point guide part in a sliding way in the medicine transfer chamber and can move forwards to a position contacting with a stopper at the front end of the needle point guide part; and a tip cap front face covering the hollow front end of the slide cylinder part, and
the tip cap front face includes: a plurality of first faller bar slots which accommodate a forward portion of each of the plurality of non-rotating faller bars; and a plurality of needle passing holes respectively connected to the first needle plate slits and passed one by the plurality of needles of the non-rotating needle plate, and
the web portion includes: second needle plate slits formed in matching relation with the first needle plate slits and accommodating rear portions of the non-rotating needle plates; and a plurality of protrusion passing holes connected to the second needle plate slits and passed one by the plurality of rear protrusions of the non-rotating needle plate until the medicine delivery chamber.
3. The needle plate stamp of claim 2,
the first needle plate slit and the second needle plate slit form a maximum width at a boundary position where they meet each other, and the width is gradually narrowed as being farther from the boundary position, the needle passage hole forms a minimum width smaller than the first needle plate slit, and the protrusion passage hole forms a minimum width smaller than the second needle plate slit.
4. The needle plate stamp of claim 2,
the support plate portion has a width gradually increased to extend to the inside of the needlepoint guide portion and allows the drug to flow to both sides of a thickness portion thereof, the connecting plate portion has a shape and a size that block a flow path of the drug delivery chamber in a region outside the plurality of second needle plate slits, and the connecting plate portion includes a plurality of assembling projections that are fitted into a plurality of assembling grooves formed in a front surface portion of the plurality of sharps.
CN201780052430.XA 2017-03-24 2017-07-31 Needle plate seal Active CN109789301B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020170037436A KR101758041B1 (en) 2017-03-24 2017-03-24 needle plate stamp
KR10-2017-0037436 2017-03-24
PCT/KR2017/008233 WO2018174347A1 (en) 2017-03-24 2017-07-31 Needle plate stamp

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CN109789301A CN109789301A (en) 2019-05-21
CN109789301B true CN109789301B (en) 2021-03-12

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WO (1) WO2018174347A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101758041B1 (en) * 2017-03-24 2017-07-14 이창우 needle plate stamp
CN109529182A (en) * 2018-11-22 2019-03-29 广州美谛医药生物科技有限公司 A kind of feedway and its beauty method of beautifying liquid

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104470577A (en) * 2012-06-12 2015-03-25 Jm生物科技株式会社 Self-injection mechanism for use on skin
KR101559525B1 (en) * 2015-04-06 2015-10-14 주식회사 지엠홀딩스 Beauty Equipment
CN205549218U (en) * 2015-01-29 2016-09-07 黄荣堂 Percutaneous micro-needle tube unit and percutaneous micro-needle tube administration device formed by same
CN106345051A (en) * 2016-11-25 2017-01-25 崔丽林 Miniature injection needle and integrated device thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090048842A (en) * 2007-11-12 2009-05-15 유지형 Roller type neddle
KR20100010105U (en) * 2009-04-07 2010-10-15 주식회사 퓨어메디 Microneedle roller
KR101608179B1 (en) 2015-11-24 2016-03-31 지승구 Device for injecting drug into skin
KR101758041B1 (en) * 2017-03-24 2017-07-14 이창우 needle plate stamp

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104470577A (en) * 2012-06-12 2015-03-25 Jm生物科技株式会社 Self-injection mechanism for use on skin
CN205549218U (en) * 2015-01-29 2016-09-07 黄荣堂 Percutaneous micro-needle tube unit and percutaneous micro-needle tube administration device formed by same
KR101559525B1 (en) * 2015-04-06 2015-10-14 주식회사 지엠홀딩스 Beauty Equipment
CN106345051A (en) * 2016-11-25 2017-01-25 崔丽林 Miniature injection needle and integrated device thereof

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