CN109731658A - A kind of capsule medicine pulverizes grading plant and its process - Google Patents
A kind of capsule medicine pulverizes grading plant and its process Download PDFInfo
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- CN109731658A CN109731658A CN201910148849.6A CN201910148849A CN109731658A CN 109731658 A CN109731658 A CN 109731658A CN 201910148849 A CN201910148849 A CN 201910148849A CN 109731658 A CN109731658 A CN 109731658A
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Abstract
The present invention provides a kind of capsule medicines to pulverize grading plant and its process, belong to grinding device technical field, including air supply system, pulverize mechanism, classification mechanism and collecting mechanism, air supply system includes oilless air compressor, the air accumulator being connect with oilless air compressor, and with the tank connected air cooling driers of gas storage, air cooling driers are connect with disintegrating mechanism, pulverizing mechanism includes charger, the ultramicro grinding room being connect with charger and the discharge port one being connect with ultramicro grinding room, classification mechanism includes grading room, grading wheel inside grading room is set, the motor being connect with grading wheel, and the discharge port two on grading room top is set, collecting mechanism includes the cyclone collector connecting with discharge port two, and the pulse backblowing bagroom being connect with cyclone collector, pulse backblowing bagroom Connect air-introduced machine.Structure of the invention is novel, and design rationally, once completes the crushing, classification and collection to drug, without dust pollution.
Description
Technical field
The invention belongs to grinding device technical fields, and in particular to a kind of capsule medicine pulverize grading plant and its
Process.
Background technique
Capsule means drug or is filled in empty hard capsule with proper auxiliary materials or is sealed in manufactured solid in soft capsule material
Body preparation can be divided into hard capsule, soft capsule (capsule and pill), spansule, controlled release capsule and capsulae enterosolubilis, main pro ore.Medicine
By drug, the solubility of drug and dissolution rate in absorption site body fluid are influenced the infiltration rate of object.Dissolution rate and drug
Surface area it is directly proportional, the drug of equivalent, particle is smaller, surface area is bigger, is more conducive to the dissolution and absorption of drug.Cause
This, superfine communication technique is had great importance applied to capsule medicine.
Ultramicro grinding and previous purely mechanic crushing are entirely different, are to carry out powder using the methods of supersonic airstream, cold slurry
It is broken.Using this technology, solid matter can be ground into superfine powder of the diameter less than 10 microns, thus, at ultramicro grinding
The powder of reason has good dissolubility, dispersibility, adsorptivity and chemical reactivity.In simple mechanical crushing, part
Mechanical energy overcomes friction to be converted into a large amount of thermal energy, has not only consumed energy but also required granularity is not achieved, and the cell pulverized
Sporoderm-broken rate is up to 90% or more.It does not generate hot-spot phenomenon in crushing process, or even can be crushed under low-temperature condition.
Speed is fast, and moment can be completed, thus, retain the bioactive ingredients of powder, to the maximum extent in favor of required height is made
Quality product.
Authorization Notice No. is that the patent of CN206334745U discloses a kind of fluidized bed airflow powder with removable jet pipe
Crushing device, including pedestal are fixed with crushing chamber enclosure by fastener on the pedestal, are equipped with top in the crushing chamber enclosure
Pulverizing chamber with opening has gap between the pulverizing chamber and feed bin, along the circumferential direction right on the side wall of the pulverizing chamber
Claim to be equipped with the nozzle block that jet pipe is equipped with inside at least two groups, one end of the nozzle block is protruded into inside pulverizing chamber, the other end
Lower part is equipped with jet pipe air inlet, and the jet pipe air inlet is connected with column type rotary air packet by escape pipe;The column type rotation
The top of air packet and the lower part of pulverizing chamber, which are closed, to be connected, and lower part passes through shaft coupling and the rotary joint phase that is installed on chassis interior
Connection.The invention can shorten the grinding time of material, effectively improve the production capacity of ultramicro grinding, but the apparatus function is single.
The patent document of Publication No. CN108097389A discloses a kind of grinding device and breaking method, wherein the powder
Crushing device includes a processing unit and a screening unit, and the processing unit includes a disintegrating mechanism;The screening unit includes
One has a separating mechanism, and a separation chamber of the separating mechanism is connected to the disintegrating mechanism, and the medicinal material is through the crushing
The crushed material that mechanism is formed after crushing is transmitted in the screening unit and carries out screening process, and the institute that will not meet standard value
It states crushed material and is transmitted in the disintegrating mechanism again.The invention complex procedures, and smashing fineness is difficult to disposably reach requirement.
Summary of the invention
The technical problem to be solved by the present invention is in view of the deficiencies of the prior art, provide a kind of capsule medicine ultra micro
Crushing and classification device, the primary crushing, classification and collection completed to drug, without dust pollution.
In order to solve the above technical problems, the technical scheme adopted by the invention is that:
A kind of capsule medicine ultramicro grinding grading plant, including air supply system, the ultramicro grinding being connect with the air supply system
Mechanism, the classification mechanism being connect with the ultramicro grinding mechanism and the collecting mechanism being connect with the classification mechanism,
The air supply system include oilless air compressor, the air accumulator being connect with the oilless air compressor and with the air accumulator
The air cooling driers of connection, the air cooling driers are connect with the disintegrating mechanism,
The ultramicro grinding mechanism include charger, the ultramicro grinding room being connect with the charger and with the ultramicro grinding
The discharge port one of room connection,
The classification mechanism includes grading room, the grading wheel being arranged in inside the grading room, the electricity connecting with the grading wheel
Machine and the discharge port two that the grading room top is arranged in, the feed inlet of the grading room are communicated with the discharge port one,
The collecting mechanism includes the cyclone collector connecting with the discharge port two and connect with the cyclone collector
Pulse backblowing bagroom, the pulse backblowing bagroom connect air-introduced machine.
Preferably, the air accumulator is connect with the air cooling driers by gas transmission pipeline one, the gas conveying
Air filter one is set on pipeline one.
Preferably, the air cooling driers are connect with the ultramicro grinding mechanism by gas transmission pipeline two, the gas
Air filter two is set on body conveyance conduit two.
Preferably, the charger is screw conveyor, the discharge port end of the screw conveyor and the Ultramicro-powder
Broken room connection.
Preferably, the bottom of the pulse backblowing bagroom is connected by gas transmission pipeline three and the air supply system
It connects, pressure gauge and pressure regulator valve is respectively set on the gas transmission pipeline three.
Preferably, the air-introduced machine connects silencer.
Above-mentioned capsule medicine pulverizes the process of grading plant, includes the following steps:
Step S1, air enters the air accumulator through the oilless air compressor, then enters the crushing through the air cooling driers
Mechanism;
Step S2, capsule medicine is delivered in the disintegrating mechanism by the charger, capsule medicine is in the powder
Enter the classification mechanism after crushing in broken mechanism, qualified powder enters the cyclone collector, unqualified return by air inducing
The ultramicro grinding room is crushed again;
Step S3: entering the powder in the cyclone collector by gas solid separation, and most of powder is collected, at least partially through
Air inducing enters the pulse backblowing bagroom, by all being collected after secondary gas solid separation, the gas discharge isolated
To atmosphere.
Compared with prior art, beneficial effects of the present invention are as follows:
The present invention provides a kind of capsule medicines to pulverize grading plant, for being pulverized to capsule medicine,
Classification and collection have height airtightness by reasonable disposition, easy to operate, and design rationally, can obtain the super of smaller particle size
Powder body.
The present invention includes air supply system, connect with air supply system ultramicro grinding mechanism, with pulverize mechanism and connect
Classification mechanism and the collecting mechanism connecting with classification mechanism, air supply system include that oilless air compressor, air accumulator and air are cold
Dry machine provides gas source to pulverize mechanism, as of the invention preferred, between air accumulator and air cooling driers air shooter
Air filter one is set on road one, so that air is obtained primary purification in this way, avoids the impurity effect air cooling driers in air
Service efficiency entered in micronizer structure by gas transmission pipeline two-way, gas by air cooling driers treated air
Conveyance conduit two is equipped with air filter two, makes to obtain air into double purification in this way, further that the air after cold do is miscellaneous
Matter removal, further increases air degree of purity, improves the efficiency of ultramicro grinding.Drug is entered by charger pulverizes room,
It is discharged after pulverizing by discharge port one, and entered in the grading room of classification mechanism through feed inlet, under the action of grading wheel
It is classified, qualified powder is entered in cyclone collector by air inducing by discharge port two, and unqualified powder falls, and returns to crushing
Room is crushed machine separating twice, until being entered in cyclone collector after qualified by air inducing;Into the big portion in cyclone collector
Point powder is collected by gas solid separation, and fraction enters in pulse backblowing bagroom, by pulse backblowing, on cloth bag
Absorption powder reduce, and effectively realize gas solid separation, further collect powder, reduce micro mist and enter environment.
Detailed description of the invention
The present invention will be further described with reference to the accompanying drawing.
Fig. 1: a kind of capsule medicine of the present invention pulverizes the structural schematic diagram of grading plant;
Fig. 2: the structural schematic diagram of the embodiment of the present invention 3;
Fig. 3: the structural schematic diagram of the embodiment of the present invention 4;
Fig. 4: the structural schematic diagram of the embodiment of the present invention 5;
Wherein, 1- oilless air compressor, 2- air accumulator, 3- air cooling driers, 4- charger, 5- pulverize room, 6- grading room, 7-
Motor, 8- discharge port two, 9- cyclone collector, 10- pulse backblowing bagroom, 11- air-introduced machine, 14- gas transmission pipeline
One, 15- air filter one, 16- gas transmission pipeline two, 17- air filter two, 18- gas transmission pipeline three, 19- pressure
Power table, 20- pressure regulator valve, 21- silencer.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Embodiment 1
Refering to fig. 1, a kind of capsule medicine pulverizes grading plant, including air supply system, the ultra micro connecting with air supply system
Disintegrating mechanism, the classification mechanism being connect with ultramicro grinding mechanism and the collecting mechanism being connect with classification mechanism,
Air supply system include oilless air compressor 1, the air accumulator being connect with oilless air compressor 2 and with the tank connected air of gas storage
Cooling driers 3, air cooling driers are connect with disintegrating mechanism,
Mechanism is pulverized to include charger 4, the ultramicro grinding room 5 connecting with charger and go out with what ultramicro grinding room was connect
Material mouth one,
Classification mechanism includes grading room 6, the grading wheel being arranged in inside grading room, the motor connecting with grading wheel 7 and setting
The feed inlet of discharge port 28 on grading room top, grading room is communicated with discharge port one,
Collecting mechanism includes the cyclone collector 9 connecting with discharge port two and the pulse backblowing cloth connecting with cyclone collector
Bag collector 10, pulse backblowing bagroom connect air-introduced machine 11.
Air supply system of the present invention selects transmission medium of the air as capsule medicine.The bottom of air accumulator need to periodically carry out
Draining, mountable automatic water trap realize Auto-drainage.
The present invention pulverizes mechanism and includes charger, pulverizes room and discharge port one, using supersonic airstream powder
Broken technology, the principle of the technology are as follows: the jet pipe that the compressed air of purge drying imports several opposite positions is formed into supersonic gas
Stream, into pulverizing chamber.Capsule medicine is sent by charger to pulverizing chamber to be accelerated by supersonic airstream, becomes high-speed motion jet stream,
It mutually hits, shear on its crosspoint;Due to forming the multiphase flow fluidized bed of high speed in pulverizing chamber, it is strong to substantially increase crushing
Degree and efficiency, to realize ultramicro grinding.The present invention can choose the three flat Supersonic of powder equipment Co., Ltd BPQ of Shanghaiization
Fast airslide disintegrating mill or granary Jinxi disintegrating apparatus Co., Ltd QBN-300 supersonic jet mill, those skilled in the art
Suitable commercial equipment may be selected according to the actual needs of capsule medicine.
Classification mechanism of the present invention includes grading room, grading wheel, motor and discharge port two, the feed inlet of grading room and discharging
Mouth one communicates, wherein the middle part of grading wheel is cavity, and top is communicated with above-mentioned discharge port two, under whole outer profile is presented greatly
Small circular platform type.The function of the mechanism is control powder granularity, so that qualified powder enters collecting mechanism by air inducing, it is unqualified
It returns to ultramicro grinding room and realizes the ultramicro grinding of capsule medicine so on circulate.Material (capsule medicine) with air-flow into
Enter grading room, generates horizontal centrifugal force field under the high speed rotation power effect of grading wheel;It, can by adjusting the revolving speed of grading wheel
The centrifugal force for adjusting material, to control material powder.Grading wheel of the present invention preferably uses vertical grading wheel, can reduce powder pair
The abrasion of grading wheel.The selectable commercial equipment of the present invention, such as: Qingdao essence micro mist equipment Co., Ltd QLF series air-flow
Pulverizing grading machine, Weifang Jinghua Powder Engineering Equipment Co.Ltd AF series gas flow sizing machine, Nanjing temmoku ultramicrotechnique are ground
Study carefully high-accuracy ultrafine powder gas flow sizing machine of development corporation, Ltd. TF etc..
Collecting mechanism of the present invention is in such a way that cyclone collector and pulse backblowing bagroom combine, so on the one hand
The pressure that cloth bag collection can be reduced can make 80 ~ 90% of powder or more to collect in cyclone collector using cyclone collector,
The load for significantly reducing pulse backblowing bagroom reduces phenomena such as bagroom blocks;On the other hand it can protect
Hold stable gas pressure: the grading of classification mechanism is that the leeway active force being subject to according to powder and powder are generated in grading wheel
It is generated in airflow field by centrifugal force comparison, therefore collecting mechanism is during operation, air quantity and wind pressure have to keep steady
It is fixed.The function of pulse backblowing bagroom mainly prevents ultrafine dust from entering environment, reduces dust emission.
As a kind of preferred embodiment of the invention, charger is screw conveyor, the discharge port end of screw conveyor
End is connect with room is pulverized.Capsule medicine is delivered to ultramicro grinding interior by screw conveyor, improves the close of device
Closing property reduces dust pollution.
Above-mentioned capsule medicine pulverizes the process of grading plant, includes the following steps:
Step S1, air enters air accumulator through oilless air compressor, then enters disintegrating mechanism through air cooling driers;
Step S2, capsule medicine is delivered in disintegrating mechanism by charger, capsule medicine crushes in disintegrating mechanism
Enter classification mechanism afterwards, qualified powder enters cyclone collector by air inducing, and unqualified return pulverizes room and carries out powder again
It is broken;
Step S3: into the powder in cyclone collector by gas solid separation, most of powder is collected, at least partially through air inducing
Into pulse backblowing bagroom, by all being collected after secondary gas solid separation, the gas isolated is emitted into atmosphere.
Embodiment 2
Refering to fig. 1, a kind of capsule medicine of the present embodiment pulverizes grading plant, unlike the first embodiment:
Air-introduced machine connects silencer 21.
Air-introduced machine uses HTD series high voltage blower, selects axial admission, single-stage cantilever cfentrifugal blower, blower tool
There is the features such as pressure is high, air quantity is big, low noise, stable, long service life, can economize on electricity 20-50% compared with other blowers, noise
Lower than 75dB, general expenses 30-45% is saved.The function of air-introduced machine be suitable, stable centripetal force is provided for classification mechanism, and
When drain heat, make system generate negative pressure, prevent powder and leak.
Embodiment 3
Referring to Fig.2, a kind of capsule medicine of the present embodiment pulverizes grading plant, it is to be carried out on the basis of embodiment 2
It improves, specifically:
Air accumulator is connect with air cooling driers by gas transmission pipeline 1, and air filter is arranged on gas transmission pipeline one
One 15.
So that air is obtained primary purification through the above technical solution, avoids the cold of the impurity effect air cooling driers in air
Dry efficiency.
According to actual needs, air filter one installs automatic water trap additional to the present invention, to exclude one bottom of air filter
Issuable condensed water.
Embodiment 4
Refering to Fig. 3, a kind of capsule medicine of the present embodiment, which pulverizes grading plant, to be carried out on the basis of embodiment 3
It improves, specifically:
Air cooling driers are connect with ultramicro grinding mechanism by gas transmission pipeline 2 16, and air is arranged on gas transmission pipeline two
Filter 2 17.
Make to obtain air into double purification through the above technical solution, further the air plankton after cold do is removed, is made
Air degree of purity further increases, the air for being purified and drying, and to improve the efficiency pulverized, avoids impurity in ultra micro
Have an adverse effect in crushing process to medicament powder.
According to actual needs, air filter two also installs automatic water trap additional to the present invention, to exclude two bottom of air filter
The issuable condensed water in portion.
Embodiment 5
Refering to Fig. 4, a kind of capsule medicine of the present embodiment, which pulverizes grading plant, to be carried out on the basis of embodiment 4
It improves, specifically:
The bottom of pulse backblowing bagroom is connect by gas transmission pipeline 3 18 with air supply system, gas transmission pipeline three
On pressure gauge 19 and pressure regulator valve 20 is respectively set.
Above-mentioned technical proposal observes convenient for staff and the input pressure of regulating gas.
Embodiment listed by the present invention, part specific embodiment only of the invention is more preferred, can also will be upper
It states embodiment and carries out organic assembling, so that the function that capsule medicine of the invention pulverizes grading plant is more, safety
Can be more preferable, operation is more convenient, controls simpler.
Finally, it is stated that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, this field is common
Other modifications or equivalent replacement that technical staff makes technical solution of the present invention, without departing from technical solution of the present invention
Spirit and scope, be intended to be within the scope of the claims of the invention.
Claims (7)
1. a kind of capsule medicine pulverizes grading plant, it is characterised in that: connect including air supply system, with the air supply system
The ultramicro grinding mechanism connect, the classification mechanism being connect with the ultramicro grinding mechanism and the receipts being connect with the classification mechanism
Collecting mechanism, the air supply system include oilless air compressor, the air accumulator being connect with the oilless air compressor and with the gas storage
Tank connected air cooling driers, the air cooling driers are connect with the disintegrating mechanism, and the ultramicro grinding mechanism includes charging
Machine, the ultramicro grinding room being connect with the charger and the discharge port one being connect with the ultramicro grinding room, the grader
Structure includes grading room, the grading wheel being arranged in inside the grading room, the motor connecting with the grading wheel and is arranged in institute
The discharge port two on grading room top is stated, the feed inlet of the grading room is communicated with the discharge port one, and the collecting mechanism includes
The cyclone collector being connect with the discharge port two and the pulse backblowing bagroom being connect with the cyclone collector,
The pulse backblowing bagroom connects air-introduced machine.
2. a kind of capsule medicine as described in claim 1 pulverizes grading plant, it is characterised in that: the air accumulator with
The air cooling driers are connected by gas transmission pipeline one, and air filter one is arranged on the gas transmission pipeline one.
3. a kind of capsule medicine as claimed in claim 2 pulverizes grading plant, it is characterised in that: the air is cold dry
Machine is connect with the ultramicro grinding mechanism by gas transmission pipeline two, and air filter is arranged on the gas transmission pipeline two
Two.
4. a kind of capsule medicine as described in any one of claims 1-3 pulverizes grading plant, it is characterised in that: described
Charger is screw conveyor, and the discharge port end of the screw conveyor is connect with the ultramicro grinding room.
5. a kind of capsule medicine as claimed in claim 4 pulverizes grading plant, it is characterised in that: the pulse backblowing
The bottom of bagroom is connect by gas transmission pipeline three with the air supply system, on the gas transmission pipeline three respectively
Pressure gauge and pressure regulator valve are set.
6. a kind of capsule medicine as claimed in claim 5 pulverizes grading plant, it is characterised in that: the air-introduced machine connects
Connect silencer.
7. the process that a kind of capsule medicine as claimed in claim 6 pulverizes grading plant, which is characterized in that packet
Include following steps:
Step S1, air enters the air accumulator through the oilless air compressor, then enters the crushing through the air cooling driers
Mechanism;
Step S2, capsule medicine is delivered in the disintegrating mechanism by the charger, capsule medicine is in the powder
Enter the classification mechanism after crushing in broken mechanism, qualified powder enters the cyclone collector, unqualified return by air inducing
The ultramicro grinding room is crushed again;
Step S3: entering the powder in the cyclone collector by gas solid separation, and most of powder is collected, at least partially through
Air inducing enters the pulse backblowing bagroom, by all being collected after secondary gas solid separation, the gas discharge isolated
To atmosphere.
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CN110201767A (en) * | 2019-06-19 | 2019-09-06 | 昆山千亿圆生物科技有限公司 | A kind of the broken wall equipment and its application method of Chinese medicine |
CN112354655A (en) * | 2020-10-21 | 2021-02-12 | 中鸿纳米纤维技术丹阳有限公司 | A smash system for nanometer grinds |
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